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Results 551 - 600 of 647
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Bhalla K K - - 1981
Patients with chronic obstructive airways disease (COAD) who also have hypertension present a particular therapeutic problem, since beta-blockers are likely to cause or aggravate bronchospasm. In this study, 25 patients with COAD and moderate benign essential hypertension were treated with indapamide 2.5 mg daily. Over the 28 week study period, ...
Perloff D - - 1981
The development of vascular complications in patients with hypertension is related to the level of blood pressure. A more representative measure of blood pressure is obtained by repeatedly measuring pressure after a period of rest or activity, and on several occasions. Really satisfactory values are, however, only obtained by multiple ...
Rao R H - - 1981
A group of essential hypertensives were treated for a period of six weeks with groundnut oil or safflower oil compared with a control group who were given a placebo medication. A significant drop in diastolic pressure occurred in the groups receiving the polyunsaturated fatty acid (PUFA) preparation. In another group ...
Grose J H - - 1980
1. Urinary excretion rate of 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), a stable nonenzymatic transformation product of prostacyclin (PGI2), was measured in 13 patients with sustained essential hypertension and in nine normotensive control subjects by a specific radioimmunoassay. 2. Patients with essential hypertension had significantly lower 6-keto-PGF1 alpha excretion rates irrespective ...
Wadden T A - - 1980
Essential hypertension is one of the leading problems seen by a family physician, and it is not easily treated. In some instances, a behavioral therapy may serve as a useful adjunct to the pharmacological treatment of this disease. Evidence indicates that relaxation therapy in combination with medical treatment results in ...
Weidmann P - - 1980
The sympathetic system, the body sodium-fluid volume state, the renin-angiotensin system, functional and structural characteristics of the heart and blood vessels, and some other components are important complementary factors in blood pressure regulation. A deviation from the normal equilibrium among these components, with a persisting non-physiologic increase in pressor factor(s) ...
Scherer B - - 1980
Essential hypertension in infancy, one believed to occur rarely if ever, is now increasingly recognized as a potential precursor of essential hypertension in adulthood. The mechanisms responsible for hypertension in childhood and adolescence are only beginning to be delineated. Renal factors assumed to be operative in juvenile hypertension are involving ...
Mandache F - - 1980
The syndrome of constitutional chronic hyperadrenalism was detected biochemically by blood cathecholamine assays as well as psychically and morphologically in 12.5% of the young apparently healthy subjects from Bucharest, investigated. Experimentally, the enzymatic cellular oxidative process in the adrenal medulla was blocked by chemical sclerosis of the adrenal medulla with ...
Reader R - - 1980
Hypertensive diseases have long been recognized as a major medical problem in Australia, but until the 1950s measures for controlling hypertension were limited and of doubtful effectiveness. Great efforts were made to identify and deal with such remediable primary causes as unilateral renal disease, endocrine disorders of the adrenal cortex ...
Păuşescu E - - 1980
Beside exerting an impressive variety of physiological and pharmacological actions on different systems of the organism, prostaglandins (PGs) may also be main factors in the pathogenesis of essential hypertension. Their role in this process is mostly explained by their multivalent interference with the tissue hormones which regulate the vascular tone ...
McCarron D A - - 1980
Disorders of calcium metabolism are not generally considered important either clinically or pathophysiologically in essential hypertension. Recent reports, though, suggest that increased parathyroid gland function may be one of the more common endocrine disturbances associated with hypertension. We measured serum parathyroid hormone (PTH) concentrations as well as routine blood and ...
de Champlain J - - 1980
Several experimental evidences have shown that, under standarized conditions, circulating catecholamines (CA) or norepinephrine (NE) levels can be used as a valid index of the sympatho-adrenal activity in animal and man. This approach in the study of hypertensive patients has permitted to uncover that about 50% of patients with labile ...
Martins e Silva J - - 1980
Red cell acetylcholinesterase activity (AChE) has been studied in 58 patients suffering from essential hypertension; diastolic blood pressure values were about 130 mm or higher in 45 patients (group A) and lower in 13 (group B). The very significant increase (p < 0.001) of AChE activity in group A has ...
Overlack A - - 1979
1. Urinary kallikrein was measured in 67 patients with essential hypertension and 25 normotensive subjects variously on unrestricted and low sodium diet. Also, the effect of orally applied hog pancreatic kallikrein on elevated blood pressure and kallikrein excretion was evaluated. 2. Urinary kallikrein was reduced in a large subgroup of ...
Garay R P - - 1979
1. The clinical applications of a simple laboratory test for the diagnosis of essential hypertension were further investigated on a large number of patients (124 individuals). 2. The reduced erythrocyte ratio of Na+/K+ net fluxes observed in essential hypertensives might be secondary to a functional defect in a Na+-K+ cotransport ...
Bali L R - - 1979
The long-term effect of relaxation in lowering blood pressure and anxiety was evaluated in this study. Eighteen male Caucasian essential hypertensives with moderate elevations in blood pressure were studied. Relaxation significantly reduced both blood pressure and anxiety. Control procedures had no significant effect. The reductions lasted for 12 months after ...
Harden R A - - 1979
A 49-year-old female with a 30-year history of untreated essential hypertension was noted to have a blood pressure of 290/175 mmHg during evaluation for elective gynecological surgery. At the time of hospitalization she complained chiefly of chronic frontal headaches. Physical examination revealed grade two hypertensive retinopathy, and laboratory studies showed ...
Chodera A - - 1979
The cardio-vascular reactions after i.m. application of 0.4 mg/kg of TA (imipramine, amitryptyline and nortryptyline) were compared in normotonics and patients suffering from essential hypertonia. It was found, that systolic blood pressure decreased significantly after the drugs only in hypertonic patients, whereas diastolic blood pressure fall was marked more in ...
Weidmann P - - 1979
The pathogenic role of the sympathetic system in essential hypertension was evaluated by combined analysis of plasma catecholamine levels and the pressor sensitivity to endogenous norepinephrine. The latter was estimated indirectly by the ratio between changes in blood pressure and those in plasma norepinephrine after adrenergic neuronal blockage with debrisoquine ...
Chan, Won-shing
(Uncorrected OCR) Abstract of thesis entitled: The sustained attention variable as a factor in the response of essential hypertensives to Benson's Meditation Technique Submitted by: Chan Won Shing for the degree of: Master of Social Sciences (Clinical Psychology) at the University of Hong Kong in April, 1979. A cognitive hypothesis ...
Ebbutt A F - - 1979
A multicentre, open study of general practice patients with essential hypertension who were currently being treated with oxprenolol and cyclopenthiazide was undertaken in which the patients were transferred to Trasidrex for 12 weeks. Weight, blood pressure, heart rate and side-effects were assessed pre-trial and at 4-week intervals. A global assessment ...
Cousineau D - - 1978
1. Average supine circulating total catecholamine concentrations were found to be higher than the normal range in about 50% of patients with labile hypertension and in about 30% of patients with sustained essential hypertension. 2. These higher resting concentrations were mainly due to an increase in adrenaline in labile hypertension ...
Fouad F M - - 1978
Cardiac output was determined in 42 young essential hypertensives (15 to 25 yrs); values ranged from 3.86 to 10.30 L./minute. These differences were not related to magnitude of volemia. Correlation of output to weekly blood pressure average (BPav) was not significant; its relationship to intraarterial pressure (BPia) was not significant ...
Hager J L - - 1978
Thirty borderline essential hypertensives were randomly assigned to a portable constant-cuff blood pressure feedback technique or meditation-relaxation. Each technique was taught in the laboratory, then practiced twice daily at home for four weeks. Subjects mailed daily records of their progress. Seven feedback and ten meditation-relaxation subjects completed the program. Both ...
Goldberg A D - - 1978
Continuous recording of intra-arterial blood pressure and electrocardiograms has been performed in 41 ambulant untreated essential hypertensive subjects for periods up to 48 hours. Statistical analysis of the results has revealed: (1) A group of patients who developed a persistent tachycardia during the day. This response was not observed in ...
Frumkin K - - 1978
Many nonpharmacologic (behavioral) techniques are being proposed for the therapy of essential hypertension. The research in this area is reviewed and divided roughly into two categories: the biofeedback and relaxation methodologies. While feedback can be used to lower pressures during laboratory training sessions, studies designed to alter basal blood pressure ...
Simon A C - - 1978
Systemic arterial compliance was measured in 22 patients with permanent essential hypertension and compared with 11 sex- and age-matched normal normal subjects. Determinations were made from analysis of the monoexponential blood pressure-time curve during diastole, according to a simple visco-elastic model. Arterial compliance was significantly decreased (P less than 0.001) ...
Caris T N - - 1978
Traditionally the initial evaluation of a patient with high blood pressure has focused on exluding secondary correctable causes of hypertension. Such all-inclusive evaluations are expensive, time-consuming, and expose the patient to some risk. A complete history, physical examination, and relatively simple laboratory procedures such as CBC, urinalysis, SMA-6 and 12, ...
Ferriss J B - - 1978
Essential hypertension is a quantitative abnormality, the pathological effects and risks increasing with the blood pressure level. In Western countries blood pressure rises with age in most individuals, so essential hypertension is more frequent in middle and older age groups. It is likely that an individual's blood pressure level is ...
Genest J - - 1978
After 30 years of continuous research into the mechanisms of human hypertension, we summarize the results obtained by the members of the multidisciplinary research group on hypertension of the Clinical Research Institute of Montreal on the disturbances of minerlocorticoid activity in a rigorously selected group of patients with early, mild ...
London G M - - 1978
Total effective vascular compliance, hemodynamic parameters, cardiopulmonary (CPBV) and total blood volumes (TBV) were determined in 31 men, including nine normotensive controls and 22 permanent essential hypertensive patients. The effective compliance was calculated from the changes in central venous pressure recorded simultaneously with the changes in blood volume obtained after ...
Voors A W - - 1978
Essential hypertension, a highly prevalent and devastating disease, likely begins in childhood, and presumably might respond at this stage to general preventive measures. The problems encountered in the recording of reproducible blood pressure levels are largely of a quantitative nature, and involve instrument validity, observer (examiner) training, and the interaction ...
Malven P V - - 1978
Brief episodes of apparently unprovoked tachycardia (increased heart rate, HR) lasting about 10--20 min were observed about one h after initiation of experimentation in 10 ovariectomized ewes which were fitted with indwelling vascular cannulae. The incidence of tachycardia episodes varied among ewes, but 99 of 215 (46%) sampling trials contained ...
Benson H - - 1978
We have investigated prospectively the efficacy of two nonpharmacologic relaxation techniques in the therapy of anxiety. A simple, meditational relaxation technique (MT) that elicits the changes of decreased sympathetic nervous system activity was compared to a self-hypnosis technique (HT) in which relaxation, with or without altered perceptions, was suggested. 32 ...
Bloem T J - - 1978
Pindolol was given for 12-15 consecutive weeks to 35 patients for the treatment of essential hypertension. Significant blood pressure reductions were achieved in the group of 28 patients who completed the trial, as tested by the Wilcoxon pair test. There was no difference in antihypertensive effect between a three times ...
Hoyt C S - - 1978
In summary, hypertension is a disproportion between vascular capacity and blood volume. Only a small number of cases are secondary to specific diseases. The vast majority of patients have so-called "essential hypertension". In many cases the causative agent seems to be aldosterone, renin. Angiotensin II or other pressor agents. Psychosocial ...
Sullivan J M - - 1977
Phenytoin or an identically appearing placebo was administered in a double-blind fashion to 20 patients with mild essential hypertension. A significant fall in supine systolic blood pressure was noted 30 minutes to 1 hour after the oral administration of 100 mg phenytoin. No significant antihypertensive effect was observed after the ...
Stumpe K O - - 1977
Plasma-prolactin concentration was up to four times higher in male patients with essential hypertension than in normotensive controls. Oral administration of bromocriptine, a dopaminergic agonist, suppressed plasma-prolactin and lowered arterial pressure. It is proposed that in the hypertensive patients the raised prolactin levels reflect a defect in central dopamine control ...
Walsh P - - 1977
In a study undertaken to evaluate the clinical effectiveness of two behavioral treatments for essential hypertension (biofeedback on arterial pulse-wave velocity and progressive relaxation) 24 hypertensive subjects were randomly assigned to either a relaxation or biofeedback treatment group for 5 weekly sessions. In a second stage of the study 16 ...
Okuwobi B - - 1977
A study of a new beta-adrenergic blocking drug TIMOLOL (Blocadren) in the treatment of essential hypertension has been undertaken. Twelve hypertensive patients previously undiagnosed and untreated were studied. Results with a twice a day dose of the drug showed a satisfactory fall in systolic and diastolic pressures in all but ...
Olsen F - - 1977
By means of the leucocyte migration technique, it has been demonstrated that the migration indices from 19 patients suffering from borderline essential hypertension are significantly different from those of 19 normal persons. These results support the view that delayed hypersensitivity directed against arterial wall components is a possible pathogenetic factor ...
Barnes K L - - 1977
Accumulating evidence suggests that the central nervous system plays a fundamental role in chronic hypertension. On the other hand, the means by which nervous factors influence the long-term control of blood pressure remain obscure. Animal models that replicate some of the functional aspects of essential hypertension in man have been ...
Knutzen V K - - 1977
The effect of various forms of hypertension on perinatal mortality has been investigated. Non-essential, non-proteinuric hypertension had relatively little effect on perinatal mortality, whereas essential and proteinuric forms of hypertension had a marked influence. Diastolic blood pressures of less than 110 mmHg did not influence perinatal mortality. Fetal loss from ...
Parving H H - - 1977
Transcapillary escape rates of albumin and IgG (fractions of intravascular mass of albumin and IgG that pass to the extravascular space per unit time) were determined simultaneously from the initial disappearance of intravenously injected 131I human albumin and 125I human IgG in seven untreated subjects suffering from essential hypertension. The ...
Ishii M - - 1977
Body fluid volumes, cardiac output, PRA and pressor responses to angiotensin II (AT) and norepinephrine (NE) were compared between untreated patients with essential hypertension aged younger than 35 (EH-I) and those aged older than 36 years (EH-II). Men blood volume, total body water and extracellular volume were not significantly different ...
Patel C H - - 1977
Based on clinical, epidemiological, and experimental work, a possible pathogenesis of essential hypertension is outlined. In the light of this possible pathogenesis, a behavioral treatment program is suggested which centers on the regular use of systematic training. Several controlled studies are described in which experimental patients given such training show ...
Scarpelli P T - - 1977
A long-term study was done by means of interative fluorangiography on microvascular retinal permeability versus the blood pressure control carried out in 11 patients with a diastolic blood pressure of greater than or equal to 130 mm Hg and with retinal exudates, haemorrhages and oedema. No matter what the original ...
Chodera A - - 1977
Imipramine in doses of 0.35-0.45 mg/kg body weight usually induces a drop in arterial blood pressure; the drop is statistically significant in patients with essential hypertension. In these patients, a significant increase in excretion of catecholamines in urine was observed when compared with a control group. In both groups no ...
Christensen C M - - 1977
Chlordimeform applied as a 0.06% low pressure spray controlled the northern fowl mite (NFM) for at least 90 days. Tetrachlorvinphos applied as a 0.5% low pressure spray was equally effective. Chi square analysis of NFM population estimates indicated that NFM populations on the untreated control birds stayed essentially the same ...
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