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Da Silva Marine S MS a Endocrinology and Nephrology, CHU de Québec Research Center, 2705 boul. Laurier, QC G1V 4G2, - - 2014
Observational studies support that dairy product intake is associated with a reduced risk of developing type 2 diabetes; however, several clinical studies report conflicting results on the association between dairy product consumption and metabolic parameters. The aim of this study was to determine associations between dairy product consumption and metabolic ...
Millen Aletta M E AM aCardiovascular Pathophysiology and Genomics Research Unit, Schools of Physiology bDepartment of Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa *Aletta M.E. Millen, Carlos D. Libhaber, Angela J. Woodiwiss, and Gavin R. Norton contributed equally to the writing of this - - 2014
AIM:: To determine whether blood pressure (BP) or an excess adiposity, both frequently observed comorbidities that independently relate to left ventricular diastolic dysfunction (LVDD), have a greater impact on LVDD at a community level. We assessed the relative independent impact of an excess adiposity versus BP on indices of LVDD ...
García-Guasch Laín L Cardiology Service, Hospital Veterinari Molins, Barcelona, - - 2014
Obesity is a risk factor in the development of several respiratory diseases. Lung volumes tend to be decreased, especially expiratory reserve volume, increasing expiratory flow limitation during tidal breathing. Barometric whole-body plethysmography is a non-invasive pulmonary function test that allows a dynamic study of breathing patterns. The objective of this ...
Harada Yuka Y Department of Respiratory Medicine, Graduate School of Medicine, Kyoto University, Kyoto, - - 2014
Obesity hypoventilation syndrome (OHS) prevalence was previously estimated at 9% in patients with obstructive sleep apnoea (OSA) in Japan. However, the definition of OSA in that study was based on an apnoea-hypopnoea index (AHI) of ≥ 20/h rather than ≥ 5/h. Therefore, the prevalence of OHS in OSA was not ...
Samuelsson Anne-Maj AM Division of Women's Health, Women's Health Academic Centre, King's College London and King's Health Partners, London, UK - - 2014
Maternal obesity is a major public health problem. Pregnant obese women have increased risk of adverse outcomes for mother and child. Recent observational studies from mother-child cohort studies suggest that obesity during pregnancy is a risk factor for the development of cardiovascular diseases in the child later in life. We ...
Pirozzi Kelly - - 2014
There is a growing body of evidence implicating obesity as having a negative effect on the development and treatment of diabetic foot disease. The aim of this study was to increase the body of knowledge on the effects of obesity on foot function, specifically as it relates to peak plantar ...
Okafor Ci C Department of Medicine, Endocrine and Metabolism Unit, College of Medicine, University of Nigeria, Enugu Campus/University of Nigeria Teaching Hospital, Ituku Ozalla, Enugu, Nigeria ; Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu, - - 2014
Obesity in developing nations is no longer as uncommon as it was thought to be decades ago however paucity of data on the burden of obesity from urban communities was observed by previous workers. To determine the magnitude of obesity and its relationship to blood pressure among urban adult residents ...
Gu Yan Y Department of Otolaryngology, Taizhou Hospital,Wenzhou Medical College, Linhai, Zhejiang, 317000, P.R. - - 2014
In the literature,there are various treatments for pseudocyst of the pinna, but their efficacy is doubtful. [1]Conservative treatments involve chemical irritation or aspiration with pressure dressing. These conservative treatments require a long course, the pseudocyst can recur and often thickness and deformity of pinna are developed [2]. This article is ...
Barnes Maria J MJ Nutrition and Neural Signaling Laboratory, Pennington Biomedical Research Center Baton Rouge, LA, - - 2014
Leptin is a hormone released from adipose tissue. While this hormone normally acts to reduce feeding behavior and increase energy expenditure, in obesity, resistance to these effects occurs even though the hormone is released in large amounts. Although leptin no longer works to suppress feeding in the obese, leptin retains ...
Schiavon Carlos Aurélio CA Research Institute HCor (Hospital do Coração, Heart Hospital) São Paulo, São Paulo, - - 2014
Obesity and overweight are becoming progressively more prevalent worldwide and are independently associated with a significant increase in the risk of cardiovascular diseases. Systemic arterial hypertension is frequently found in association with obesity and contributes significantly to increased cardiovascular risk. We hypothesise that Roux-en-Y gastric bypass (RYGB) surgery, a procedure ...
Li Tai-Shun TS School of Public Health. Wanna Medical College. Wuhu 241002. China.. - - 2014
The aim of the study is to examine the distribution of integrated covariate and its association with blood pressure (BP) among children in Anhui province, China, and assess the predictive value of integrated covariate to children hypertension. A total of 2,828 subjects (1,588 male and 1,240 female) aged 7-17 years ...
Xie Yao Jie YJ Department of Sports Science and Physical Education, the Chinese University of Hong Kong, Hong Kong SAR, - - 2014
To assess the validity of self-reported weight, height, body mass index (BMI), waist circumference and blood pressure compared with standardized clinical measurements and to determine the classification accuracy in overweight/obesity and central adiposity. This pilot study was integrated into a life-course study entitled "Hong Kong Women's Health Study" among 1,253 ...
Petit J S - - 2013
The causes of hemodynamic instability in acute pancreatitis are numerous. Although pericardial effusion during pancreatitis is common, a cardiac tamponade is rarely reported. The diagnosis of compressive cardiac disorders (CDD) by echocardiography is easily reported when the patient is breathing spontaneously; it becomes difficult when the patient is assisted with ...
Daste Thomas - - 2013
A domestic shorthair cat was referred for progressive muscle weakness and dyspnoea. The cat had a 2-month history of severe weight loss, small intestinal diarrhoea, polyphagia and polyuria/polydypsia. Biochemical analysis and venous blood gas evaluation revealed severe hypokalaemia [1.7 mmol/l; reference interval (RI): 3.5-5.1 mmol/l] and hypoventilation (partial pressure of ...
Chikamoto Akira - - 2013
The division of the pancreatic parenchyma using a stapler is important in pancreatic surgery, especially for laparoscopic surgery. However, this procedure has not yet been standardized. We analyzed the effects of the closing speed of stapler jaws using bovine pancreases for each method. Furthermore, we assigned 10 min to the slow ...
Trepte Constantin J C - - 2013
PURPOSE: Severe acute pancreatitis (SAP) remains a life-threatening disease with classic etiology of systemic inflammatory response and mortality between 30 and 50 %. The aim of the present study is to compare two different treatment strategies of goal-directed hemodynamic management and evaluate their impact on survival, microcirculation, tissue oxygenation, and histopathologic ...
Mifkovic A - - 2013
Intra-abdominal hypertension (IAH) contributes to organ dysfunction and leads to the development of the abdominal compartment syndrome (ACS). IAH and ACS are relatively frequent findings in patiens with severe acute pancreatitis (SAP) and are associated with deterioration in organ functions. The most affected are cardiovascular, respiratory and renal functions. The ...
Dai Ruiwu - - 2012
There is not any stable, repeatable, and clinically simulated animal model of isolated pancreatic trauma been established as yet. The aim of our study is to establish a small animal model that mimics the pathophysiology of isolated pancreatic blast trauma and to study the features of traumatic condition in the ...
Truijen Jasper - - 2012
Monitoring of continuous blood pressure and cardiac output is important to prevent hypoperfusion and to guide fluid administration, but only few patients receive such monitoring due to the invasive nature of most of the methods presently available. Noninvasive blood pressure can be determined continuously using finger cuff technology and cardiac ...
Chierichetti Monica - - 2012
: In acute lung injury, atelectasis is common and frequently develops in the dependent and diaphragmatic regions. Attempts to recruit lung with positive pressure constitute a major aim in the management of acute respiratory distress syndrome but are associated with overdistension and injury in nonatelectatic regions. : To test the ...
Mansouri Kaweh - - 2012
Intraocular pressure (IOP) is a major risk factor for glaucoma and lowering IOP remains the mainstay of glaucoma treatment. Current glaucoma management usually relies on single IOP measurements during clinic hours despite the fact that the majority of glaucoma patients have their highest IOP levels outside clinic hours. The fact ...
Bingger P - - 2012
An innovative procedure for measuring blood pressure, with none of the disadvantages of current procedures, is proposed. A highly-flexible capacitive strain gauge has been designed to measure changes in the diameter of a blood vessel; such changes are indicative of blood pressure. The sensor is implanted and wrapped around an ...
Mansouri K - - 2012
Glaucoma is the main cause of irreversible blindness and intraocular pressure (IOP) is its only modifiable risk factor. The importance of robust lowering of IOP for prevention of glaucoma onset and progression is well established. Although IOP is a dynamic parameter with individual circadian rhythms, current management usually relies on single ...
Adebayo A M AM Department of Community Medicine, University College Hospital, - - 2011
Currently, population based medical check up is yet to be explored as a veritable tool for assessing the burden of non-communicable diseases in Nigeria. This study aimed to assess the prevalence of selected lifestyle related diseases during a free medical rally in an urban community. General medical examinations of all ...
Raekallio M R - - 2010
We investigated whether administration of L-659,066, a peripheral α(2) -adrenoceptor antagonist, or verapamil, a calcium-channel antagonist, would prevent the cardiovascular effects of dexmedetomidine. Eleven sheep received three intravenous treatments with a randomized, cross-over design: dexmedetomidine (5 μg/kg, DEX); DEX with L-659,066 (250 μg/kg, DEX + L); and verapamil (0.05 mg/kg) ...
Luewan Suchaya - - 2011
To determine hypotensive effect of nifedipine in the treatment of preterm labor. A descriptive analytic study was conducted on pregnant women treated with nifedipine as tocolytic drug for preterm labor. Maternal blood pressure before and at 15, 30, 45 and 60 min after administration of nifedipine was evaluated and analyzed. Hypotension ...
Pollak P T - - 2010
During the introduction of a new once-daily nifedipine 60 mg osmotic delivery tablet to Canada in 2009, several patients previously maintained at target blood pressure on regimens that included nifedipine 60 mg daily were observed to have > 10 mmHg rises in their systolic pressure during follow-up. The only difference ...
Hashimoto Ryo - - 2010
It has been shown that the calcium antagonist nifedipine upregulates superoxide dismutase (SOD). Although the peroxisome proliferator-activated receptor (PPAR) response element is located in the promoter region of Cu/ZnSOD, it remains unclear whether nifedipine upregulates PPARs and inhibits vascular remodeling. We hypothesthized that nifedipine activates PPARgamma, inhibits vascular remodeling, and ...
Elliott H L - - 2011
A retrospective analysis of the database from A Coronary Disease Trial Investigating Outcome with Nifedipine (ACTION) evaluated the effectiveness of nifedipine gastrointestinal therapeutic system (GITS) (i) in combination with renin angiotensin system (RAS) blockers and (ii) in patients with isolated systolic hypertension (ISH). Analysed on an intention-to-treat basis, treatment groups ...
Yui Yoshiki - - 2010
BACKGROUND: Although antihypertensive therapy reduces cardiovascular events, it is unclear whether there are differences in cardiac remodeling and function between treatments with nifedipine retard and angiotensin-converting enzyme inhibitors (ACE-Is). It is also not clear how antihypertensive therapy influences cardiac remodeling and function. METHODS: Hypertensive patients with coronary artery disease were ...
Nakagawa Kumiko - - 2010
The purpose of this study was to examine the effects of ingestion of grapefruit juice or grapefruit on the hypotensive effect and plasma concentration of dihydropyridine calcium antagonists, i.e., amlodipine and nifedipine. A 50-year-old man with essential hypertension was studied. Grapefruit juice (500 ml) was taken together with the antihypertensive ...
Aydin Mehmet Dumlu - - 2009
Nifedipine is a therapeutic drug in acute attacks of hypertension because of its rapid absorption from oral mucosa. Taste receptors are innervated by glossopharyngeal nerves (GPN) as well as by facial and vagal nerves. Sensory neurons of the GPNs are localised in the petrous ganglion (PG). Transection of the taste ...
Kodama Sunao - - 2009
The aim of the present study was to examine the antihypertensive and antihypertrophic effects of combined treatment with a long-acting calcium antagonist on top of an angiotensin II receptor blocker (ARB) in uncontrolled hypertensive patients. Patients with essential hypertension and a blood pressure > 140/90 mmHg on ARB monotherapy (losartan ...
Beig Mirza Irfan - - 2009
Epileptic seizures are accompanied by changes in autonomic function that in turn influence the cardiovascular system (hypertension and bradyarrhythmia). We have studied possible cardioprotective activity (during the ictal state in conscious animals) of valproic acid, nifedipine, and verapamil, alone and in combination, during pentylenetetrazole (PTZ)-induced seizures. Telemetry system was used ...
Fukuda Michinari - - 2009
The aim of this study was to compare the effects of nifedipine coat-core (once daily formulation) and amlodipine on systemic arterial stiffness in patients with hypertension. Study drugs were assigned by the randomized open-label crossover method. After the blood pressure was maintained below 130/85 mm Hg for 8 months by ...
Pise Mayurika - - 2009
The effectiveness of long acting nifedipine (Nicardia retard 10/20/30 CD) was evaluated on Indian patients in multiple centres. This was an open, prospective, clinical multicentric trial. Nearly 1632 patients satisfying the inclusion criteria were selected and given long acting nifedipine and assessed regularly for a period of one month. The ...
Zemanc?kov? A - - 2009
It is documented that in chronic hypertensive state there is an increased vasodepressor response to calcium channel antagonists such as the dihydropyridine derivate nifedipine. This effect is generally proportional to initial blood pressure as was demonstrated in several models of experimental hypertension. In the present study we investigated the effect ...
Iida Satofumi - - 2008
The aims of the study were 1) to evaluate the pharmacokinetics of nicorandil in healthy subjects and acute heart failure (AHF) patients and 2) to evaluate the exposure-response relationship with pulmonary arterial wedge pressure (PAWP) in AHF patients and to predict an appropriate dosing regimen for nicorandil. Based on the ...
Nakou E - - 2008
OBJECTIVE: The management of obese hypertensive subjects may require the administration of anti-obesity and antihypertensive drugs. Sibutramine use has raised concerns regarding a potential increase in subjects' blood pressure and heart rate. The primary end-points of this study were an evaluation of the effect of sibutramine together with a verapamil ...
Callan Mary Beth - - 2008
BACKGROUND: The safety and feasibility of plateletpheresis using a commercially available apheresis system (COBE Spectra, Gambro BCT) were evaluated in donor dogs, with characterization of its clinical and clinicopathologic effects. STUDY DESIGN AND METHODS: Fourteen adult dogs (18-27.7 kg) underwent a plateletpheresis procedure. Complete blood counts were obtained at baseline, ...
Curwen Jon O - - 2008
Inhibition of vascular endothelial growth factor-A (VEGF) signaling is a key therapeutic approach in oncology given the role of VEGF in angiogenesis and vascular permeability in solid tumors. Clinical trials examining VEGF signaling inhibitors commonly report hypertension. We examined the effect of cediranib, a highly potent VEGF signaling inhibitor, on ...
Soukhova-O'Hare Galia K - - 2008
Obstructive and central apneas during sleep are associated with chronic intermittent hypoxia (CIH) and increased cardiovascular morbidity. Spontaneously hypertensive rats exposed to CIH during postnatal days 4 to 30 develop exaggerated hypertension as adults. We hypothesized that reactive oxygen species and altered L-Ca(2+) channel activity may underlie the postnatal programming ...
Hinoi Toshihide T Department of Internal Medicine, Kure Kyosai Hospital, Kure, Japan. - - 2008
Hypertension and insulin resistance are associated with reduced coronary vasodilatory capacity, possibly caused by structural changes in the coronary resistance vessels. The goal of this study was to compare the effect of an angiotensin receptor blocker (ARB) with that of a calcium channel blocker (CCB) on coronary flow reserve and ...
Tomita Naruya - - 2008
Agents to inhibit the renin-angiotensin system have been reported to suppress the progression of abdominal aortic aneurysm (AAA). However, the effects of calcium channel blockers (CCBs) are still unclear in terms of the inhibition of the progression of AAA. Recently, several effects of CCBs beyond those associated with blood pressure ...
Bell David - - 2008
Chronic inhibition of nitric oxide (NO) synthesis is associated with hypertension, myocardial ischemia, oxidative stress and hypertrophy; expression of adrenomedullin (AM) and intermedin (IMD) and their receptor activity modifying proteins (RAMPs 1-3) is augmented in cardiomyocytes, indicating that the myocardial AM/ IMD system may be activated in response to pressure ...
Ryuzaki Munekazu - - 2007
OBJECTIVE: We developed a new data collection system named i-converter that could transmit data to a website via cellular phone. Using the system, we compared the effects of two calcium channel blockers on the home blood pressure. METHODS: Amlodipine and nifedipine CR were administered to 41 patients with essential hypertension ...
Kamezaki Fumihiko - - 2007
Large-scale clinical studies have indicated that angiotensin receptor blockers (ARBs) have beneficial effects against cardiovascular diseases. We designed this study to compare the effects of an ARB and a calcium channel blocker (CCB) on coronary flow velocity reserve (CFVR), a predictor of cardiovascular events, as estimated using transthoracic Doppler echocardiography. ...
Bäumer Anselm T - - 2007
The vascular NAD(P)H oxidase contributes to endothelial dysfunction and high blood pressure in the spontaneously hypertensive rat by enhancing superoxide production. We investigated the effects of apocynin, a NAD(P)H oxidase inhibitor, on blood pressure and vascular radical and nitric oxide formation in SHR and compared its effects to the calcium ...
Tinel Hanna - - 2007
BACKGROUND: The antihypertensive and organ-protective effects of the combination of the angiotensin II type 1 receptor blocker losartan and the calcium channel blocker nifedipine were examined in Dahl salt-sensitive rats. METHODS: The rats fed with a high-salt diet developed hypertension accompanied by aorta and heart hypertrophy, and impaired renal function. ...
Davenport Kim - - 2007
Drugs are increasingly being used to promote stone passage in renal colic. Diclofenac, nifedipine and tamsulosin cause ureteric smooth muscle relaxation in vitro; however, in clinical trials nifedipine and tamsulosin promote stone passage whereas diclofenac has no apparent benefit. We adapted a ureteric pressure transducer catheter in an attempt to ...
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