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Arora Pankaj P University of Alabama at Birmingham, Birmingham, - - 2014
-A large body of epidemiological and experimental evidence suggests that vitamin D deficiency may promote hypertension. This raises the possibility that vitamin D supplementation could be a simple intervention to reduce blood pressure, but data from prospective, randomized trials are limited. -A double-blind, randomized controlled trial was conducted at 4 ...
Mozaffari-Khosravi Hassan H aDepartment of Nutrition, Faculty of Health bDepartment of Internal Medicine cGeneral Courses Department, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, - - 2014
The present evidence indicates a reverse correlation between vitamin D status and blood pressure (BP). The present study determined the effect of oral vitamin D supplementation on BP in patients with elevated BP and vitamin D deficiency. In this randomized, double-blind, placebo-controlled trial, 42 outpatients with elevated BP and vitamin ...
Hodgson Jonathan M JM School of Medicine and Pharmacology, University of Western Australia,GPO Box - - 2014
High blood pressure (BP) variability, which may be an important determinant of hypertensive end-organ damage, is emerging as an important predictor of cardiovascular health. Dietary antioxidants can influence BP, but their effects on variability are yet to be investigated. The aim of the present study was to assess the effects ...
de Moraes Augusto César Ferreira AC Department of Preventive Medicine, School of Medicine of the University of São Paulo, São Paulo, Brazil; GENUD-Growth, Exercise, Nutrition and Development Research Group, University of Zaragoza, Zaragoza, Spain; Faculty of Health Sciences of the University of Zaragoza, Zaragoza, Spain. Electronic address: - - 2014
Previous research showed that low concentration of biomarkers in the blood during adolescence (i.e., iron status; retinol; and vitamins B6, B12, C, and D) may be involved in the early stages of development of many chronic diseases, such as hypertension. The aim was to evaluate if iron biomarkers and vitamins ...
Li Fu F Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, - - 2014
To observe the effect of cholecystectomy on the changes of motion pattern of Beagle dogs' sphincter of Oddi (SO), and investigate the modulatory role of nitric oxide (NO) and cholecystokinin (CCK) in the regulation of SO. Pressure of common bile duct, SO motility, response to bolus injections of cholecystokinin (CCK, ...
Gurusamy Kurinchi Selvan KS Department of Surgery, Royal Free Campus, UCL Medical School, Royal Free Hospital, Rowland Hill Street, London, UK, NW3 - - 2014
A pneumoperitoneum of 12 to 16 mm Hg is used for laparoscopic cholecystectomy. Lower pressures are claimed to be safe and effective in decreasing cardiopulmonary complications and pain. To assess the benefits and harms of low pressure pneumoperitoneum compared with standard pressure pneumoperitoneum in people undergoing laparoscopic cholecystectomy. We searched ...
Singla Sanjeev S Associate Professor, Department of Surgery, Dayanand Medical College and Hospital , Ludhiana, India - - 2014
Abdominal pain and shoulder tip pain after laparoscopic cholecystectomy are distressing for the patient. Various causes of this pain are peritoneal stretching and diaphragmatic irritation by high intra-abdominal pressure caused by pneumoperitoneum . We designed a study to compare the post operative pain after laparoscopic cholecystectomy at low pressure (7-8 ...
Kundra Pankaj P Departments of *Anaesthesiology and Critical Care §Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research †Department of Anaesthesiology, Sri Lakshmi Narayana Institute of Medical Sciences ‡Department of Anaesthesiology and Critical Care, Mahatma Gandhi Medical College and Research Institute, Pondicherry, - - 2014
Applying appropriate positive end-expiratory pressure (PEEP) to corresponding intra-abdominal pressure (IAP) can improve gas exchange during capnoperitoneum without any hemodynamic effects. A total of 75 patients were randomly allocated to group 0PEEP (n=25), group 5PEEP (n=25), and group 10PEEP (n=25) according to the level of PEEP, in whom capnoperitoneum was ...
Hua Jie J Department of General Surgery, Shanghai Tenth People's Hospital, Tongji University of Medicine, 301 Yanchang Middle Road, Shanghai 200072, China; Department of General Surgery, First Clinical Medical College of Nanjing Medical University, Nanjing, - - 2014
The feasibility and safety of low-pressure pneumoperitoneum in laparoscopic cholecystectomy remain unclear. A meta-analysis of randomized controlled trials comparing low-pressure with standard-pressure pneumoperitoneum was performed. A total of 1,263 patients were included. Low-pressure pneumoperitoneum was associated with significantly decreased postoperative pain. The requirement for increased pressure was significantly greater in ...
Gupta Ranjan - - 2013
Abstract Background: Laparoscopic cholecystectomy at standard-pressure pneumoperitoneum uses a pressure of 12-14 mm Hg, which may cause a variety of adverse physiological changes involving the respiratory, cardiovascular, and hepatorenal systems reflected as subclinical abnormalities in biochemical parameters. The use of low-pressure pneumoperitoneum in the range of 8-10 mm Hg has been shown ...
Vega-Gálvez Antonio A Department of Food Engineering, Universidad de La Serena, Avenida Raúl Bitrán s/n, Box 599, La Serena, Chile ; Center for Advanced Studies in Arid zones, CEAZA, Universidad de La Serena, Avenida Raúl Bitrán s/n, Box 599, La Serena, - - 2014
The aim of this work was to study the effect of high hydrostatic pressure (HHP) on colour, dietary fibre, vitamin C content, polysaccharides content, physico-chemical and structural properties of aloe vera gel at three pressure levels (300, 400 and 500 MPa for 3 min) after 35 days of storage at 4 ± 1 °C. The results ...
Gupta Sampa Dutta - - 2012
The maintenance of oxygenation is a commonly encountered problem in obese patients undergoing laparoscopic cholecystectomy. There is no specific guideline on the ventilation modes for this group of patients. Although several studies have been performed to determine the optimal ventilatory settings in these patients, the answer is yet to be ...
Umar Asif A Department of Surgery, Dr. Ram Manohar Lohia Hospital New Delhi, New Delhi, 110001 India ; Top Floor 25 Kailash Hills, New Delhi, 110065 - - 2013
Biliary diseases known since ages constitute major portion of digestive tract disorders world over. Among these cholelithiasis being the fore runner causing general ill health, thereby requiring surgical intervention for total cure. The study was undertaken in an attempt to compare the hemodynamic changes in patient undergoing laparoscopic cholecystectomy using ...
Ozyuvaci E - - 2012
Transcutaneous, arterial and end-tidal measurements of carbon dioxide were compared in patients (American Society of Anesthesiology physical status classes II and III) with chronic obstructive pulmonary disease (COPD) who underwent laparoscopic cholecystectomy with carbon dioxide insufflation. General anaesthesia was performed in all patients. The Sentec(®) system was used for transcutaneous ...
Vega-Gálvez Antonio A Department of Food Engineering, Universidad de La Serena, Avenida Raúl Bitrán s/n, Box 599, La Serena, Chile; Center for Advanced Studies in Arid zones, CEAZA, Universidad de La Serena, Avenida Raúl Bitrán s/n, Box 599, La Serena, Chile. Electronic address: - - 2011
The aim of this study was to evaluate the effects of high hydrostatic pressure treatment at three pressure levels (300, 400 and 500Mpa) on the functional and quality characteristics of Aloe vera gel including vitamin C and E, aloin, minerals, phenolic content and antioxidant activity. The results show that HHP ...
Harmell Alexandrea L AL Joint Doctoral Program in Clinical Psychology, University of California-San Diego/San Diego State University, CA, - - 2011
To examine whether high levels of self-efficacy for problem-focused coping were significantly related to several resting BP measures in spousal Alzheimer's disease caregivers. Cross-sectional. Participants included 100 older caregivers (mean age = 73.8 ± 8.14 years) providing in home care for a spouse with Alzheimer's disease. All participants completed a ...
Brummett Beverly H - - 2011
To replicate a prior main effect of the serotonin transporter gene promoter (5HTTLPR) genotype on cardiovascular reactivity (CVR) and explore caregiver stress as a potential moderator of 5HTTLPR effects on CVR. On the basis of prior findings, we hypothesized that the more transcriptionally active allele variants would be associated with ...
Futier Emmanuel - - 2010
Pulmonary function is impaired during pneumoperitoneum mainly as a result of atelectasis formation. We studied the effects of 10 cm H2O of positive end-expiratory pressure (PEEP) and PEEP followed by a recruitment maneuver (PEEP+RM) on end-expiratory lung volume (EELV), oxygenation and respiratory mechanics in patients undergoing laparoscopic surgery. Sixty consecutive ...
te Pas Arjan B AB Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands. - - 2011
Neonatal resuscitation guidelines do not specify the gas flow rate during mask ventilation. Investigating the effect of gas flow rates on pressures, volumes delivered and mask leak. Flow 5 and 10 liters/min were tested. In study part 1, pressure ranges were measured when ventilating an intubated manikin with a Neopuff®. ...
Kredel Markus - - 2011
ABSTRACT The separate effects of positive end-expiratory pressure (PEEP) and intravascular volume administration on the histopathologic lung injury were not investigated in experimental lung injury previously. The authors hypothesized that high PEEP and a restrictive volume therapy would yield the best oxygenation and the least degree of lung injury. Pigs ...
Cesana B M - - 2010
The results of meta-analyses on the effectiveness of high positive end-expiratory pressure (PEEP) and prone positioning in acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) are not consistent. In addition, the meta-analyses on the activated protein C in patients with sepsis combine trials with discordant results. Therefore, the aim of ...
Piccin Vivien S - - 2011
To evaluate the effects of different mechanical ventilation (MV) strategies on the mucociliary system. Experimental study. Twenty-seven male New Zealand rabbits. After anesthesia, animals were tracheotomized and ventilated with standard ventilation [tidal volume (Vt) 8 ml/kg, positive end expiratory pressure (PEEP) 5 cmH(2)O, flow 3 L/min, FiO(2) 0.4] for 30 ...
Bouhemad Belaïd - - 2011
In the critically ill patients, lung ultrasound (LUS) is increasingly being used at the bedside for assessing alveolar-interstitial syndrome, lung consolidation, pneumonia, pneumothorax, and pleural effusion. It could be an easily repeatable noninvasive tool for assessing lung recruitment. Our goal was to compare the pressure-volume (PV) curve method with LUS ...
Froessler B - - 2010
Spontaneous ventilation is a popular mode of ventilation for patients with the laryngeal mask airway (LMA). Studies have shown, however, that spontaneous ventilation impairs gas exchange and that assisting or controlling ventilation results in higher oxygen saturation. Atelectasis during general anesthesia is a well described mechanism which impacts on gas ...
Hodd Jack - - 2010
To estimate the ability of simulated tracheal suction, adjusting the positive end expiratory pressure (PEEP) settings on the ventilator or compressing a self-inflating bag to minimize aspiration during cuff deflation and extubation in a bench-top model. During intubation, colonized secretions accumulate in the subglottic space above the endotracheal tube (ETT) ...
Tusman Gerardo - - 2010
BACKGROUND: We studied the effects that the lung recruitment maneuver (RM) and positive end-expiratory pressure (PEEP) have on the elimination of CO(2) per breath (Vtco(2,br)). METHODS: In 7 healthy and 7 lung-lavaged pigs at constant ventilation, PEEP was increased from 0 to 18 cm H(2)O and then decreased to 0 ...
Dargaville Peter A - - 2010
To determine whether, during mechanical ventilation, an optimal positive end-expiratory pressure (PEEP) can be identified by measurement of regional tidal volume and compliance [V (T(reg)), C (RS(reg))]. Sixteen anaesthetized intubated neonatal piglets underwent a stepwise vital capacity manoeuvre performed during pressure control ventilation, with 5 cmH₂O PEEP increments to 25 ...
Rocco Patricia R M - - 2010
In patients with acute lung injury and acute respiratory distress syndrome, a protective mechanical ventilation strategy characterized by low tidal volumes has been associated with reduced mortality. However, such a strategy may result in alveolar collapse, leading to cyclic opening and closing of atelectatic alveoli and distal airways. Thus, recruitment ...
Staffieri Francesco - - 2010
OBJECTIVE: To evaluate the effects of 10 cm H(2)O of positive end-expiratory pressure (PEEP) on lung aeration and gas exchange in mechanically ventilated sheep during general anesthesia induced and maintained with propofol. ANIMALS: 10 healthy adult Bergamasca sheep. PROCEDURES: Sheep were sedated with diazepam (0.4 mg/kg, IV). Anesthesia was induced ...
da Silva Almeida Juliana Roberta - - 2010
BACKGROUND: To evaluate the cardiopulmonary effects of positive end-expiratory pressure (PEEP) equalization to intra-abdominal pressure (IAP) in an experimental model of intra-abdominal hypertension (IAH) and acute lung injury (ALI). METHODS: Eight anesthetized pigs were submitted to IAH of 20 mm Hg with a carbon dioxide insufflator for 30 minutes and ...
Bickenbach Johannes - - 2010
Regional inhomogeneity and alveolar mechanics in a porcine model of acute lung injury (ALI) was evaluated using confocal laser scanning microscopy (CLSM). CLSM was performed through thoracic windows of the upper and lower lobes. Image quantification was conducted by use of a volume air index (VAI). Twelve anesthetized, mechanically ventilated ...
Tripathi Ravi S - - 2010
In ICU patients with acute lung injury, the pulse oximetry saturation (Spo(2)) to fraction of inspired oxygen (Fio(2)) (S/F) ratio is a reliable surrogate measure for the P/F (Pao(2)/Fio(2)) ratio. Our goal was to determine the correlation of the S/F to the P/F in a large sample of patients undergoing ...
Parra Celso Augusto Martins CA CET/SBA of HCFMUSP, São Paulo, SP. - - 2010
Perioperative hypoxemia is common in cardiac surgeries, and atelectasis is the main cause. Besides, we can mention extracorporeal circulation (ECC), dissection of internal thoracic arteries, and previous clinical status of the patient among others as its causes. The present study elaborated an anonymous questionnaire to observe ventilatory strategies for hypoxemia ...
Isgrò Stefano - - 2010
We investigated the effects of periodical high pressure breaths (SIGH) or biphasic positive pressure ventilation (BIPAP) during helmet continuous positive airway pressure (CPAP) in patients with acute hypoxic respiratory failure. We used a recently developed electromechanical expiratory valve (TwinPAP, StarMed, Mirandola, Italy), which is time-cycled between two customizable positive end-expiratory ...
Futier Emmanuel - - 2010
BACKGROUND AND OBJECTIVE: Induction of anaesthesia promotes collapse of dependent lung regions in both obese and nonobese patients. We hypothesized that end-expiratory lung volume (EELV) may be more sensitive than oxygenation to evaluate the effects of positive end-expiratory pressure (PEEP) after anaesthesia induction. METHODS: Forty patients (20 nonobese patients and ...
Marcus Hanke E - - 2010
BACKGROUND: Increasing the cross-sectional area (CSA) of the right internal jugular vein facilitates cannulation and decreases complications. Maneuvers such as the Trendelenburg tilt position and ventilation with a positive end-expiratory pressure (PEEP) may increase the CSA of the right internal jugular vein. We determined the changes in the CSA in ...
Iannuzzi M - - 2010
The aim of this study was to test if different recruitment maneuver (RM) patterns, that achieve the same maximum pressure for the same length of time in humans, have a similar efficacy on alveolar recruitment, intrathoracic vascular pressures and flows, and on cardiac function and ventricular filling. Forty patients were ...
Iannuzzi M - - 2010
AIM: The aim of this study was to test if different recruitment maneuver (RM) patterns that achieve the same maximum pressure for the same length of time in humans have a similar efficacy on alveolar recruitment, intrathoracic vascular pressures and flows, and on cardiac function and ventricular filling. METHODS: Forty ...
Zhang Xiang-Yu - - 2011
Traumatic brain injury or intracranial hemorrhage patients with acute lung injury/acute respiratory distress syndrome need mechanical ventilation. The use of positive end-expiratory pressure (PEEP) in this situation remains controversial. This study explored the impact of PEEP on intracranial pressure (ICP), cerebral perfusion pressure (CPP), central venous pressure (CVP), and mean ...
Dehne Marius G - - 2010
INTRODUCTION: Positive pressure ventilation influences hemodynamics and impairs renal function. The effects of inverse ratio ventilation (IRV) on hormonal response and renal function need to be investigated because this represents a highly invasive form of positive pressure ventilation. MATERIALS AND METHODS: Ten male patients were treated postoperatively for 60 min ...
Lesur Olivier - - 2010
To investigate the hemodynamic and outcome effects of implementing prophylactic positive end-expiratory pressure (PEEP) versus zero end-expiratory pressure (ZEEP) in patients during the postintubation period in the emergency setting. The present study was a prospective, single-centre, interventional, single-blinded randomized trial performed in a 16-bed medical intensive care unit. The study ...
Passath Christina - - 2010
BACKGROUND: Neurally adjusted ventilatory assist (NAVA) delivers airway pressure (Paw) in proportion to neural inspiratory drive as reflected by electrical activity of the diaphragm (EAdi). Changing positive end-expiratory pressure (PEEP) impacts respiratory muscle load and function and, hence, EAdi. We aimed to evaluate how PEEP affects the breathing pattern and ...
Hollenbeck Kerry J - - 2010
We tested whether positive end-expiratory pressure (PEEP) increases right internal jugular vein (RIJV) cross-sectional area (CSA) in 45 ASA physical status I and II adults. All patients received a standardized IV fluid bolus, induction of general anesthesia, tracheal intubation, and mechanical ventilation. We evaluated the CSA of the RIJV using ...
Lumb A B - - 2010
BACKGROUND: Atelectasis is known to develop during anaesthesia and after operation atelectasis leads to impaired oxygenation. Lung recruitment manoeuvres, positive end-expiratory pressure (PEEP), and continuous positive airway pressure (CPAP) have been proposed for reduction of atelectasis but their benefits have not been shown to persist after operation. We proposed that ...
Cabello Belén - - 2010
PURPOSE: To compare cardiovascular and respiratory responses to different spontaneous breathing trials (SBT) in difficult-to-wean patients using T-piece and pressure support ventilation (PSV) with or without positive end-expiratory pressure (PEEP). METHODS: Prospective physiological study. Fourteen patients who were monitored with a Swan-Ganz catheter and had failed a previous T-piece trial ...
Desebbe Olivier - - 2010
BACKGROUND: Pleth variability index (PVI) is a new algorithm allowing automated and continuous monitoring of respiratory variations in the pulse oximetry plethysmographic waveform amplitude. PVI can predict fluid responsiveness noninvasively in mechanically ventilated patients during general anesthesia. We hypothesized that PVI could predict the hemodynamic effects of 10 cm H2O ...
Saner Fuat H - - 2010
STUDY OBJECTIVE: To assess the effect of positive end-expiratory pressure (PEEP) up to 15 cm H(2)O on blood flow throughput of the liver and its effects on systemic hemodynamics in patients following liver transplantation. DESIGN: Prospective, interventional study. SETTING: Intensive care unit (ICU) of a university hospital. PATIENTS: 74 consecutive ...
Tadié Jean-Marc - - 2010
The change in exhaled NO after cardio-pulmonary bypass remains controversial. The aims were to determine whether exhaled NO sources (alveolar or bronchial) are modified after bypass, and whether mechanical ventilation (MV) settings during bypass modify exhaled NO changes. Thirty-two patients were divided into three groups: without MV during bypass and ...
Liu Hui - - 2010
BACKGROUND: High positive end-expiratory pressure (PEEP) and low tidal volume (VT) ventilation is thought to be a protective ventilation strategy. It is hypothesized that the stabilization of collapsible alveoli during expiration contributes to lung protection. However, this hypothesis came from analysis of indirect indices like the analysis of the pressure-volume ...
Gattinoni Luciano - - 2010
PURPOSE OF REVIEW: In the last 2 years, several reports have dealt with recruitment/positive end-expiratory pressure (PEEP) selection. Most of them confirm previous results and few add new information. RECENT FINDINGS: It has been definitely confirmed that opening pressures are different throughout the acute respiratory distress syndrome lung parenchyma, ranging ...
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