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Coelho Prabhu Nayantara N Division of Gastroenterology and Hepatology, Mayo Clinic, 200 1st Street Southwest, Rochester, MN 55905, - - 2015
Acute gastrointestinal bleeding is a common cause for hospitalization. Endoscopic hemostasis plays a central role in the management of lesions with active bleeding or high-risk stigmata for rebleeding. The efficacy and safety of endoscopic hemostasis rely on the identification of lesions suitable for endoscopic therapy, selection of the appropriate hemostatic ...
Bi Wei-Ping WP Wei-Ping Bi, Hui-Bin Man, Department of Internal Medicine, Wendeng Central Hospital, Wendeng 264400, Shandong Province, - - 2014
Gastric ulcer is a common disorder of the digestive system. Current therapeutic regimens largely rely on Western medicine. However, numerous studies have demonstrated that herbal medicines can effectively treat gastric ulcer in humans and various animal models via divergent mechanisms. This review updates the efficacy and safety of herbal medicines ...
Miller Linda L Foundation for the Accreditation of Cellular Therapy, University of Nebraska Medical Center , Omaha, - - 2014
The emergence of regenerative medicine raises new questions about the best ways to ensure the safety and efficacy of stem cell therapies for patients. The Foundation for the Accreditation of Cellular Therapy (FACT) believes minimum requirements for cellular therapy for regenerative medicine will promote patient safety, protect the research environment, ...
Singer Sara J SJ *Harvard School of Public Health †Harvard Medical School ‡Mongan Institute for Health Policy, Massachusetts General Hospital §Division of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Boston, MA ∥Bureau of Health Care Safety and Quality, Massachusetts Department of Public Health, Boston, MA ¶North Shore Medical Center, Salem, MA #Center for Surgery and Public Health, Brigham and Women's Hospital, Boston **Institute for Healthcare Improvement, Cambridge, MA ††Massachusetts Coalition for the Prevention of Medical Errors, Burlington, - - 2014
Ambulatory practices deliver most health care services and contribute to malpractice risk. Yet, policymakers and practitioners often lack information about safety and malpractice risk needed to guide improvement. To assess staff and administrator perceptions of safety and malpractice risk in ambulatory settings. We administered surveys in small-sized to medium-sized primary ...
Almén A A Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, SE-413 45 Gothenburg, Sweden - - 2014
Quality assurance has been identified as an important part of radiation protection and safety for a considerable time period. A rational expansion and improvement of quality assurance is to integrate radiation protection and safety in a management system. The aim of this study was to explore factors influencing the implementing ...
Nute Christine C Cardiothoracic intensive care, University Hospital of Wales, - - 2014
Most nurses are involved in medicines management, which is integral to promoting patient safety. Medicines management is prone to errors, which depending on the error can cause patient injury, increased hospital stay and significant legal expenses. This article describes a new approach to help minimise drug errors within healthcare settings ...
Bala Veenu - - 2014
Dithiocarbamates are considered as the simplest occurring organosulfur compounds exhibiting diverse chemical and medicinal versatility. Dithiocarbamates have been used as pesticide in the 20th century but thereafter they have attracted the interest of medicinal chemists due to their metal binding capacity. Recently a variety of chemical and medicinal properties of ...
McDonald Cameron J CJ Quality Use of Medicines and Pharmacy Research Centre, Sansom Institute, School of Pharmacy and Medical Sciences, University of South Australia, GPO Box 2471, Adelaide, SA, 5001, - - 2014
Concerns with the safety profiles of the newer anticoagulants have been raised because of differences in treatment populations between pre-marketing studies (randomized controlled trials) and clinical practice. Little is known about the potential safety issues and the reporting in spontaneous adverse event databases associated with rivaroxaban. To analyse spontaneous adverse ...
De Hert Stefan S - - 2014
This review summarises the new insights into the physiology of perioperative fluid therapy and analyses recent studies of the safety of the use of HES solutions in the fluid management of critically ill patients. This analysis reveals a number of methodological issues in the three major studies that have initiated ...
Owen Micheal D K MD Iowa State - - 2014
There is interest in more diverse weed management tactics because of evolved herbicide resistances in important weeds in many US and Canada crop systems. While herbicide resistances in weeds is not new, the issue has become critical because of the adoption of simple, convenient and inexpensive crop systems based on ...
Knechtges Paul P Department of Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin. Electronic address: - - 2014
The Toyota Production System, also known as Lean, is a structured approach to continuous quality improvement that has been developed over the past 50 years to transform the automotive manufacturing process. In recent years, these techniques have been successfully applied to quality and safety improvement in the medical field. One ...
Pires Carla C School of Pharmacy, Research Institute for Medicines and Pharmaceutical Sciences, University of Lisbon, Lisbon, - - 2014
Package leaflets are necessary for safe use of medicines. The aims of the present study were: 1) to assess the compliance between the content of the package leaflets and the specifications of the pharmaceutical regulations; and 2) to identify potential safety issues for patients. Qualitative descriptive study, involving all the ...
Panesar Sukhmeet S SS Department of Primary Care and Public Health, Imperial College London, W6 8RP, - - 2014
The aim of this qualitative study is to better understand the types of error occurring during the management of cardiac arrests that led to a death. All patient safety incidents involving management of cardiac arrests and resulting in death which were reported to a national patient safety database over a ...
Julius Alex K AK University of Massachusetts - Amherst, Department of Environmental Conservation, United States. Electronic address: - - 2014
Arboriculture is hazardous work. A consensus safety standard exists, but little is known about compliance with it. This study aimed to determine whether accreditation and certification are associated with safety practices and to identify specific safety practices adhered to most and least. Sixty-three tree care companies in southern New England ...
Rousse Carole C ASN - French Nuclear Safety Authority, 15 rue Louis Lejeune, Montrouge 92541, France - - 2014
The analysis of events is crucial for accident prevention. In 2007, ASN set up a system for the notification of radiation protection events. The majority of them concern the exposure of patients undergoing therapeutic or diagnostic procedures and, to a lesser extent, occupational exposures and the management of radioactive effluents. ...
Cuvelier L L Laboratoire Paragraphe, Equipe C3U, Université Paris 8, 2 rue de la Liberté, 93526 Saint-Denis Cedex, France. Electronic address: - - 2015
This exploratory research aims to understand how teams organize themselves and collectively manage risky dynamic situations. The objective is to assess the plausibility of a model of a collective trade-off between "understanding" and "doing". The empirical study, conducted in the pediatric anesthesia service of a French university hospital, was supported ...
Comer Eamon - - 2014
Here, we describe medicinal chemistry that was accelerated by a diversity-oriented synthesis (DOS) pathway, and in vivo studies of our previously reported macrocyclic antimalarial agent that derived from the synthetic pathway. Structure-activity relationships that focused on both appendage and skeletal features yielded a nanomolar inhibitor of P. falciparum asexual blood-stage ...
Chinou Ioanna I University of Athens, Faculty of Pharmacy, Div. of Pharmacognosy and Chemistry of Natural, Products, University Campus of Zografou, Athens 15771, Greece. Electronic address: - - 2014
According to Directive 2004/24/EC which amended the basic legislation laid down in Directive 2001/83/EC a new European legislation on herbal medicinal products was developed, in order to harmonise the use of herbal medicinal products in member states of the European Union. The objective of this legislation was to ensure the ...
Agos Florence F Orthopedic Surgery Unit, The Queen's Medical Center, Kamehameha 3 Makai, 1301 Punchbowl Street, Honolulu, HI 96813, USA; Surgical Short Stay Unit, The Queen's Medical Center, Kamehameha 3 Makai, 1301 Punchbowl Street, Honolulu, HI 96813, USA. Electronic address: - - 2014
Perioperative hyperglycemia management is an important factor in reducing the risk of surgical site infections (SSIs) in all patients regardless of existing history of diabetes. Reduction of SSIs is one of the quality indicators reported by the National Healthcare Safety Networks of the Centers for Disease Control and Prevention (CDC). ...
Levy Jerrold H JH Duke University School of Medicine, Divisions of Cardiothoracic Anesthesiology and Critical Care, Duke University Hospital, 2301 Erwin Road, Durham, NC 27710, USA. Electronic address: - - 2014
New oral anticoagulants (NOACs) are increasingly replacing vitamin K antagonists and older parenteral agents in clinical practice. NOACs offer several advantages compared with standard agents, including rapid onset of action, fixed dosing, and no requirement for routine coagulation monitoring. However, like all anticoagulants, NOACs carry a risk of bleeding. Here, ...
Klahn Shawna S Department of Small Animal Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, 205 Duck Pond Drive, Blacksburg, VA 24061, USA. Electronic address: - - 2014
Exposure to chemotherapy is a health hazard for all personnel in facilities that store, prepare, or administer antineoplastic agents. Contamination levels have been measured as much as 15 times higher in the veterinary medicine sector than in human facilities. Recent publications in human and veterinary medicine indicate that exposure extends ...
Kiani Fariba F Young Researchers and Elite Club, Shahrekord Branch, Islamic Azad University, Shahrekord, - - 2014
Researchers have found that management safety practices may predict occupational injuries and psychological distresses in the workplace. The present study examined the perception of management safety practices related to injuries reporting and its dimensions among workers of Isfahan Steel Company (ESCO). A self-administered anonymous survey was distributed to 189 workers. ...
Fuentes Eduardo E Cirad, UMR Innovation, 73 Avenue Jean-François Breton, 34398, Montpellier, France, - - 2014
In developing countries, milk quality is often mismanaged in relation to husbandry practices, collection logistics, and the production of small batches. This paper investigates how the management of milk quality from farm to dairy processor impacts on both chemical and hygienic indicators, in a context characterized by farm scale diversity, ...
Bezerra Carvalho Ana Cecília AC Agência Nacional de Vigilância Sanitária, Coordenação de Medicamentos Fitoterápicos, Dinamizados e Notificados. Adress: SIA, Trecho 5, Área especial 57, Bloco A/B. ZIP CODE: 71.200-980, Brasília-DF, Brazil. Electronic address: - - 2014
Ethnopharmacological relevance: Rich Brazilian biodiversity is accompanied by a long acceptance of medicinal plants and traditional knowledge by the Brazilian population. To improve the regulatory framework for herbal medicines in Brazil, ANVISA recently revised it's legislations. Aim of the study: To discuss the new Brazilian standards for herbal medicines regulation. ...
Wiesner Jacqueline J Federal Institute for Drugs and Medical Devices, K.-G.-Kiesinger-Allee 3; 53175 Bonn, Germany. Electronic address: - - 2014
Each application for authorisation of a medicinal product must be accompanied by the particulars and documents referred to in Directive 2001/83/EC on the Community code relating to medicinal products for human use. Details on the documentation needed for traditional herbal medicinal products (THMP) are given in article 16c of the ...
Murphy Sean V SV Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, - - 2014
Additive manufacturing, otherwise known as three-dimensional (3D) printing, is driving major innovations in many areas, such as engineering, manufacturing, art, education and medicine. Recent advances have enabled 3D printing of biocompatible materials, cells and supporting components into complex 3D functional living tissues. 3D bioprinting is being applied to regenerative medicine ...
Wang Yun Fei YF Department of Traditional Chinese Surgery, Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine, 725 South Wan-ping Road, Shanghai, Shanghai, China, - - 2014
Skin and soft-tissue infections (SSTIs) are common infections of the epidermis, dermis or subcutaneous tissue. SSTIs range in severity from minor, self-limiting, superficial infections to deep, aggressive, gangrenous, life-threatening infections. Some classifications divide SSTIs into 'complicated' and 'uncomplicated' infections based on clinical severity. Treatments of SSTIs involves antibiotic therapy, surgical ...
Ryu Seungmi S Interdisciplinary Program for Bioengineering, Seoul National University, Seoul 151-744 - - 2014
Carbon-based materials have been extensively studied for stem cell culture. However, difficulties associated with engineering pure carbon materials into 3D scaffolds have hampered applications in tissue engineering and regenerative medicine. Carbonized polyacrylonitrile (cPAN) could be a promising alternative, as cPAN is a highly ordered carbon isomorph that resembles the graphitic ...
Irving Anne V - - 2014
Reviewing the liability claims management process provides a window into patient safety.
Helitzer D L - - 2014
Limited research has explored pesticide injury prevention among American Indian farmers. In a five-year agricultural intervention, a university-community partnership, including the University of New Mexico School of Medicine, New Mexico State University, Shiprock Area Cooperative Extension Service, and Navajo Nation communities, used a culturally relevant model to introduce and maintain ...
Aronne Louis J LJ Weill Cornell Medical College Medical Director, Center for Weight Management and Metabolic Clinical Research, New York, NY, - - 2014
Over the past decade, treatment for obesity has been limited because of an incomplete understanding of the pathophysiology of obesity, lack of recognition of it as a disease, and limited efficacy of treatment options. Safety concerns related to medical and surgical approaches for obesity have also been a major barrier. ...
Khurana Tina T Department of Anesthesiology and Intensive Care, Maulana Azad Medical College, Lok Nayak Hospital, New Delhi, - - 2014
The anesthetic management of a parturient with an intracranial tumor can be quite challenging for the anesthetist as it requires a fine balance of both maternal and fetal safety. The literature pertaining to anesthetic management of such cases is limited. We describe the anesthetic management and peri-operative concerns of this ...
Kneisl Jeffrey S JS Department of Orthopaedic Surgery, Levine Cancer Institute, Carolinas Healthcare System, Charlotte, North - - 2014
Adult soft tissue sarcomas (STSs) are heterogeneous neoplasms that account for 11,410 new diagnoses and 4,390 deaths per year. This article summarizes recent NCCN guidelines for diagnosis and management of STSs of the extremities and retroperitoneum, as well as gastrointestinal stromal tumors (GIST). AJCC staging and recently reported NCDB data ...
Giangreco Adam A *Lungs for Living Research Centre, Division of Medicine, University College London, Gower Street, London WC1E 6BT, - - 2014
The field of regenerative medicine offers tantalizing hope for the repair and replacement of damaged organs and tissues, with the ultimate goal of restoring normal tissue function. This field represents an enormous range of biological, chemical and biophysical technologies that harness the restorative properties of living materials, especially human cells, ...
Zhang Chao C Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, North Carolina 27157; Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, - - 2014
Repair and reconstruction of damaged tissues and organs has been a major issue in the medical field. Regenerative medicine and tissue engineering, as rapid evolving technologies, may offer alternative treatments and hope for patients with serious defects and end-stage diseases. Most urologic diseases could benefit from the development of regenerative ...
Gressgård Leif Jarle LJ Department of Social Science, International Research Institute of Stavanger, Bergen, - - 2014
In a safety perspective, efficient knowledge management is important for learning purposes and thus to prevent errors from occurring repeatedly. The relationship between knowledge exchange among employees and safety behavior may be of particular importance in distributed organizational systems where similar high-risk activities take place at several locations. This study ...
Crompton Joseph G JG National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA; Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge CB2 2QH, UK; Department of Surgery, University of California Los Angeles, Los Angeles, CA 90095, - - 2014
Regenerative medicine holds great promise in replacing tissues and organs lost to degenerative disease and injury. Application of the principles of cellular reprogramming for the treatment of cancer, however, is not well established. Here, we present an overview of cellular reprogramming techniques used in regenerative medicine, and within this context, ...
Watson Brendan M BM Department of Bioengineering, Rice University, 6500 Main Street, Houston, TX 77030, - - 2014
Disease and injury have resulted in a large, unmet need for functional tissue replacements. Polymeric scaffolds can be used to deliver cells and bioactive signals to address this need for regenerating damaged tissue. Phosphorous-containing polymers have been implemented to improve and accelerate the formation of native tissue both by mimicking ...
Wu Xiaoyan X College of Pharmaceutical Science, Nanjing University of Chinese Medicine, Nanjing, People's Republic of - - 2014
Recently, combination therapy with acupuncture and medicine as a practical strategy to treat diseases has gained increasing attention. The present study aimed to investigate whether acupuncture stimulation at ST.36 had a potential impact on the pharmacokinetics and tissue distribution of lignans. An HPLC-ESI/MS analytical method was established and successfully applied ...
Baillargeon Amanda L AL Graduate Program of Biomedical Engineering, Faculty of Engineering, The University of Western Ontario, London, ON, Canada N6A - - 2014
Degradable biomaterials continue to play a major role in tissue engineering and regenerative medicine as well as for delivering therapeutic agents. Although the chemistry of polyphosphazenes has been studied extensively, a systematic review of their applications for a wide range of biomedical applications is lacking. Polyphosphazenes are synthesized through a ...
Kumar Rakesh R Department of Paediatric and Preventive Dentistry, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, - - 2014
Gingival enlargement or overgrowth (GO) is a common complication of the anticonvulsant drug phenytoin (PHT). GO is evident in almost half of the patients receiving PHT therapy. PHT-induced gingival overgrowth (PGO) is more common in children than in adults and affects both males and females equally. PGO may vary from ...
Shetty Anil A Public and Population Health, Northland District Health Board, Whangarei, New - - 2014
Reducing the rate of acute rheumatic fever nationally by two-thirds by 2017 is a New Zealand Ministry of Health priority. Northland District Health Board (DHB) has high rates of rheumatic fever, disproportionately impacting on Maori children and young people. School-based programmes and general practice both contribute to rheumatic fever prevention ...
Parand Anam A Department of Surgery & Cancer, Imperial College London, London, - - 2014
To review the empirical literature to identify the activities, time spent and engagement of hospital managers in quality of care. A systematic review of the literature. A search was carried out on the databases MEDLINE, PSYCHINFO, EMBASE, HMIC. The search strategy covered three facets: management, quality of care and the ...
Fernández Oscar O Neurology Department & Institute of Clinical Neurosciences, Regional University Hospital, Málaga, - - 2014
Clinical trials demonstrate the efficacy and tolerability of an intervention under experimental conditions, but information on use under daily practice conditions is required to confirm the effectiveness and safety of new management options. Clinical outcomes for THC:CBD oromucosal spray (Sativex®) in patients with treatment-resistant MS spasticity have been collected in ...
Andersson Erik E Stockholm Resilience Centre, Stockholm University, Stockholm, - - 2014
Worldwide conservation goals to protect biodiversity emphasize the need to rethink which objectives are most suitable for different landscapes. Comparing two different Swedish farming landscapes, we used survey data on birds and vascular plants to test whether landscapes with large, intensively managed farms had lower richness and diversity of the ...
Rägo Lembit L Department of Essential Medicines and Health Products, World Health Organization, Geneva, Switzerland. - - 2014
Medicines of uncertain quality, safety and efficacy can be worse than no treatment at all. It is the responsibility of national medicines regulatory authorities to protect patients from harm. Yet, there are great disparities in regulatory capacity globally, preventing large populations from accessing the benefits of advances in the pharmaceutical ...
Correia S I SI 3B's Research Group-Biomaterials, Biodegradables and Biomimetics, University of Minho, , Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, S. Cláudio de Barco, Taipas, Guimarães 4806-909, - - 2014
Tissue engineering and regenerative medicine (TERM) has caused a revolution in present and future trends of medicine and surgery. In different tissues, advanced TERM approaches bring new therapeutic possibilities in general population as well as in young patients and high-level athletes, improving restoration of biological functions and rehabilitation. The mainstream ...
Wang Yan - - 2013
Hydrogel system, as one of the most important biomaterials, is widely studied because of its tremendous potential in regenerative medicine conferred by its wide range of malleable biochemical and physical characteristics, which include its biocompatibility with the elemental biomolecules in vital tissues, its high water retention capability and adjustable soft-tissue-like ...
Solos Ioannis - - 2013
The ancient teacher-disciple tradition is regarded as one of the most celebrated practices within the Chinese medicine world. Such traditions of secrecy, private wisdom and honor are deeply rooted in the theories of Confucianism. This paper only explores the surface of this ancient culture, by investigating relevant popular ancient texts ...
Shang Yuezai - - 2013
Elastin-like polypeptides (ELPs) are artificial biopolymers composed of the pentapeptide repeat Val-Pro-Gly-Xaa-Gly. They are a class of stimuli responsive biopolymers exhibiting an inverse temperature transition, which are particularly attractive in biological applications. In this paper, the methods of synthesizing ELPs and the applications in medicine and biotechnology such as purification ...
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