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Jayakumar Thanasekaran T Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, 110, Taiwan, - - 2014
Stroke is an important cause of mortality and morbidity worldwide but effective therapeutic strategy for the prevention of brain injury in patients with cerebral ischemia is lacking. Although tissue plasminogen activator has been used to treat stroke patients, this therapeutic strategy is confronted with ill side effects and is limited ...
Miao Melissa M Department of Speech Pathology, Faculty of Health Sciences, University of Sydney , Cumberland Campus C43S, Lidcombe New South Wales , Australia - - 2014
Abstract Purpose: Although clinical practice guidelines can facilitate evidence-based practice and improve the health outcomes of stroke patients, they continue to be underutilised. There is limited research into the reasons for this, especially in speech pathology. This study provides the first in-depth, qualitative examination of the barriers and facilitators that ...
Sluggett Janet K JK Quality Use of Medicines and Pharmacy Research Centre, Sansom Institute for Health Research, University of South Australia, Adelaide, SA, Australia. - - 2014
Objective: To examine recent trends in the use of secondary stroke prevention medicines by transient ischaemic attack (TIA) and ischaemic stroke survivors. Design, setting and participants: Retrospective observational study of patients aged ≥ 65 years who were hospitalised with a TIA or ischaemic stroke between January 2000 and December 2009. Use ...
Yuwen Ya Y Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, 100700, - - 2014
To systematically review the clinical practice guidelines (CPGs) for ischemic stroke in Chinese medicine (CM) with the Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument. CM CPGs for ischemic stroke were searched in 5 online databases and hand-searches in CPG-related handbooks published from January 1990 to December 2012. ...
Lio Peter A PA Departments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Ill. Electronic address: - - 2014
Atopic dermatitis is a challenging condition for clinicians and patients. Recent advances were documented in the Atopic Dermatitis Practice Parameter 2012, and we want to provide clinicians with key points from the Atopic Dermatitis Practice Parameter 2012. In this article, we highlight the evidence-based therapy of atopic dermatitis as well ...
Gaire Bhakta Prasad BP Department of Herbal Pharmacology, College of Korean Medicine, Kyung Hee University, Seoul, 130-701, Korea, - - 2014
Scutellaria baicalensis Georgi is the most widely used medicinal plant in traditional Eastern medicine, especially in Chinese medicine. The major phytochemicals isolated from S. baicalensis are flavonoids, glycosides and their glucoronides such as baicalin, baicalein, wogonin etc. More than 30 different kinds of flavonoids are isolated from this plant. S. ...
Miller Joseph J Department of Emergency Medicine, Henry Ford Hospital, Detroit, MI. Electronic address: - - 2014
Elevated blood pressure is present in more than 60% of patients with acute stroke. Moderate to severe hypertension affects stroke outcomes, yet the optimal management has been a gray area in the care of such patients. Although new data are changing the approach, particularly for hemorrhagic events, significant questions remain. ...
Calapai Gioacchino G Department of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy; Operative Unit of Clinical Pharmacology, Azienda Ospedaliera Universitaria Policlinico 'G. Martino', 98125 Messina, - - 2014
This review focuses on contact dermatitis as an adverse effect of a selection of topically used herbal medicinal products for which the European Medicines Agency has completed an evaluation up to the end of November 2013 and for which a Community herbal monograph has been produced. Part 1: Achillea millefolium ...
Souter Caroline C Pharmacy Department, Western General Hospital, Edinburgh, - - 2014
The objectives of this study are to explore stroke patients' and carers' beliefs and concerns about medicines and identify the barriers to medication adherence for secondary stroke prevention. Qualitative semistructured one-on-one interviews were conducted with 30 patients with diagnosis of stroke. Interviews were analysed using the framework approach. The study ...
Harris Joshua D JD Houston Methodist Hospital, Center for Orthopaedics and Sports Medicine, Houston, Texas, U.S.A.; Division of Sports Medicine, Department of Orthopedic Surgery, Rush Medical College of Rush University, Rush University Medical Center, Chicago, Illinois, U.S.A.. Electronic address: - - 2014
The purpose of this investigation is to determine the proportion of sports medicine studies that are labeled as Level I Evidence in 5 journals and compare the quality of surgical and nonsurgical studies using simple quality assessment tools (Consolidated Standards of Reporting Trials [CONSORT] and Jadad). By use of PRISMA ...
Pollack Allan A Family Medicine Research Centre, University of Sydney, New South - - 2014
In 2012, about 50 000 Australians had a stroke (cerebrovascular accident (CVA)). The risk of stroke is associated with increased age, previous stroke or transient ischaemic attack, hypertension, smoking, diabetes mellitus (DM), hypercholesterolaemia and atrial fibrillation/flutter (AF). Australian general practice data from the national BEACH program between April 2000 and ...
McEnery-Stonelake Melissa M From the *University of Massachusetts Medical School; and †UMass Memorial Medical Center, Worcester, - - 2014
Excipients in various formulations of active drugs occasionally include known contact allergens. Their ingestion may trigger dermatitis or cause it to become widespread or refractory to therapy. The aim of this study was to investigate the prevalence of common contact allergens among the excipients of oral antihistamines available in this ...
Berge E E Department of Internal Medicine, Oslo University Hospital, Oslo, - - 2014
The Cochrane Stroke Group was one of the first specialist review groups set up within The Cochrane Collaboration and has been in existence for 20 years. Its key outputs include a number of high profile reviews in the area of the management of stroke, which have become one of the ...
Zhang Qian Q State Key Laboratory of Quality Research in Chinese Medicine, Faculty of Chinese Medicine, Macau University of Science and Technology, Macao 999078, Macao SAR of P. R. - - 2014
Ischemic stroke is a clinical acute disease which causes neurological dysfunction and threatens a patient's life. Because the mechanism of pathology is complicated and most patients miss the best therapeutic window time, the effect of the treatment is not satisfied at present. Numerous studies indicated new vessels not only recuperated ...
Wallach Daniel D Department of Dermatology, Hôpital Tarnier-Cochin, Paris, - - 2014
Atopic dermatitis was described in 1933 but exists since antiquity. We review descriptions of a childhood skin disease compatible with our modern diagnosis of atopic dermatitis, in ancient medicine and in nineteenth century dermatology texts. We identify Hebra's prurigo and Besnier's diathetic prurigo as forerunners of atopic dermatitis, the latter ...
Polívka Jiří J Department of Neurology, Faculty of Medicine in Pilsen, Charles University in Prague, Alej Svodody 80, Pilsen 304 60, Czech Republic ; Department of Neurology, University Hospital Pilsen, Alej Svodody 80, Pilsen 304 60, Czech - - 2014
Primary and secondary prevention of ischemic stroke represents a significant part of stroke management and health care. Although there are official guidelines concerning stroke management, new knowledge are introduced to them with a slight delay. This article provides an overview of current information on primary and secondary prevention of ischemic ...
Nouh Amre A Department of Neurology, Stritch School of Medicine, Loyola University Chicago , Maywood, IL , - - 2014
Posterior circulation strokes represent approximately 20% of all ischemic strokes (1, 2). In contrast to the anterior circulation, several differences in presenting symptoms, clinical evaluation, diagnostic testing, and management strategy exist presenting a challenge to the treating physician. This review will discuss the anatomical, etiological, and clinical classification of PC ...
Zhang Han H 0000-0001-8815-4378 Department of Electrical and Computer Engineering, Cleveland State University, Cleveland, OH 44115, - - 2014
The traditional Chinese medicine (TCM) is explained in the language of engineering cybernetics (EC), an engineering science with the tradition of rigor and long history of practice. The inherent connection is articulated between EC, as a science of interrelations, and the Chinese conception of Wuxing. The combined cybernetic model of ...
Bu Youngmin - - 2013
Although many agents for acute ischemic stroke treatment have been developed from extensive preclinical studies, most have failed in clinical trials. As a result, researchers are seeking other methods or agents based on previous studies. Among the various prospective approaches, vascular protection might be the key for development of therapeutic ...
Yang A-Li - - 2013
Based on the pathophysiology of the brain, advance in angiogenesis induced by stroke, and evidences of Chinese-medicine-mediated angiogenesis, the possibility to study the stroke-treating mechanism of Chinese medicine in angiogenesis was discussed. And regarding our previous work on angiogenesis modulated by qi-tonifying and stasis-eliminating therapy following intracerebral hemorrhage, we proposed ...
Liu Xuan X Shanghai Research Center for TCM Modernization, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P.R. - - 2013
Pharmacology as a modern science was introduced in China approximately 150 years ago, and has been used since then to study traditional Chinese medicine (TCM). Pharmacology has experienced its own development over this time and continues to provide new tools for the study of TCM. In the present review, three ...
Das Sujata S Department of Neuropsychology, Fortis Hospitals, Anandapur, Kolkata, - - 2013
Rising stroke and higher mortality among Indian population needs focused attention for prevention and early management of stroke. In India, very few studies have been carried out to determine the causes of deficiencies in knowledge, attitude and practice (KAP) of stroke among Indians. Study on KAP is essential to improve ...
Rahimi Roja - - 2013
To evaluate the efficacy and tolerability of herbal medicines in inflammatory bowel disease (IBD) by conducting a meta-analysis. Electronic databases were searched for studies investigating efficacy and/or tolerability of herbal medicines in the management of different types of IBD. The search terms were: "herb" or "plant" or "herbal" and "inflammatory ...
Zargaran Arman - - 2013
Stroke or cerebrovascular accident (CVA) is caused by a disturbance of the blood supply to the brain and an accruing loss of brain function. The first recorded observations were in 2455BC and it has been studied intensely by ancient physicians throughout history. In the early medieval period, Ibn Sina (980-1025AD) ...
Wu M L - - 2013
Background. Realgar (arsenic sulfide) is thought to be safe with few reports on toxicities or adverse effects and has been used in Traditional Chinese Medicine for many centuries. Serious realgar poisoning is rare, and we report a fatal case resulted from short-term use of realgar-containing herbal medicine through dermal route. ...
Ellis Harold - - 2013
Claude Bernard is rightly regarded as one of the founders of modern experimental studies in medicine. This year marks the 200th anniversary of his birth, on 12 July 1813 in St. Julien, France, just south of the Swiss border, opposite Geneva.
Dewald Tracy A - - 2013
Anticoagulation for the prevention of stroke is an important aspect of the management of atrial fibrillation. Novel anticoagulants including oral factor Xa inhibitors rivaroxaban and apixaban and the direct thrombin inhibitor dabigatran have emerged as important therapeutic treatment options for prevention of stroke in non-valvular atrial fibrillation. These agents offer ...
Wasser G - - 2013
The course of events in ischemic strokes is normally seen from a point in which the penumbra is already in place. Since there is no known treatment for edema reduction, mainstream medicine focuses on re-opening the occluded vessel. Here we show that reducing the penumbra saves neuronal units from undergoing ...
Elfrink Marlies E C - - 2013
BACKGROUND: The effects of maternal use of medicines during pregnancy on tooth development has scarcely been studied; only negative effects of tetracycline on tooth germs are known (irreversible tooth discoloration and enamel hypoplasia). OBJECTIVE: The aim of this study was to investigate whether antibacterials and anti-allergic and anti-asthma medicines, being ...
Toyoda Kazunori - - 2013
Background: Different aspects of acute stroke management and strategies for stroke prevention derive from two viewpoints: specific traditional and historical backgrounds and evidence-based medicine from modern randomized controlled trials (RCTs), meta-analysis and authorized clinical practice guidelines (GLs). Regarding intracerebral hemorrhage (ICH), Cerebrovascular Diseases published the 2006 European stroke initiative recommendations ...
Kern Rolf - - 2013
Background: Different aspects of acute stroke management and strategies for stroke prevention derive from two viewpoints: specific traditional and historical backgrounds and evidence-based medicine from modern randomized controlled trials (RCTs), meta-analysis and authorized clinical practice guidelines (GLs). Regarding stroke, GLs have been published by national and international organizations in different ...
Andújar Isabel - - 2013
Shikonin is the major constituent of the root of Lithospermum erythrorhizon, which has been used in traditional Chinese medicine to treat external wounds, burns, and dermatitis for centuries. Nowadays, this root is commonly used as an herbal medicine against cancer. Studies carried out over the past 30 years have demonstrated ...
Anderson Jane - - 2013
We conducted a pilot study to determine the feasibility of using videoconferencing for a programme of self-management to prevent stroke (V-STOP). A total of 37 Veterans with a history of stroke, or with multiple risk factors for stroke, were enrolled in the study from two rural sites. The V-STOP intervention ...
Norris Meriel - - 2013
Abstract Purpose: Self-management is being increasingly promoted within chronic conditions including stroke. Concerns have been raised regarding professional ownership of some programmes, yet little is known of the professional's experience. This paper aims to present the views of trained therapists about the utility of a specific self-management approach in stroke ...
Vidal Sarkis Morales - - 2013
Stroke is one of the most common causes of morbidity and mortality in hospitalized patients in the United States. A proper understanding of stroke mechanisms helps to guide specific case management. The only therapy approved by the US Food and Drug Administration for the management of acute ischemic stroke is ...
Rohde Alexia - - 2013
RATIONALEAIMS AND OBJECTIVES: Aphasia affects up to 38% of stroke survivors. Clinical guidelines can improve patient care and outcomes. Given the importance of aphasia management in stroke care, the purpose of this study was to systematically search for, retrieve and assess the quality of currently published clinical guidelines for aphasia ...
Ranta Annemarei - - 2013
Transient ischaemic attacks (TIAs) indicate high risk for stroke and rapid management reduces stroke burden. Rapid specialist access to initiate timely management is often challenging to achieve. To assess the feasibility of implementing a TIA/Stroke electronic decision support (EDS) tool intended to aid general practitioners (GPs) in the timely management ...
Ranta Annemarei - - 2013
Rapid expert management of transient ischemic attacks (TIA) has been shown to reduce the incidence of stroke, but is not always achievable. This study aims to demonstrate that TIA management by stroke experts is indeed more guideline adherent than that of generalists and that a TIA/stroke electronic decision support (EDS) ...
Kim Ellie J Y - - 2012
ETHNOPHARMACOLOGICAL RELEVANCE: While there is an increasing number of toxicity report cases and toxicological studies on Chinese herbal medicines, the guidelines for toxicity evaluation and scheduling of Chinese herbal medicines are lacking. AIM: The aim of this study was to review the current literature on potentially toxic Chinese herbal medicines, ...
Dunnick June K - - 2012
Toxicity studies were conducted by the National Toxicology Program (NTP) to provide information on the potential for toxicity from long-term use of commonly used herbal medicines. Here, we review the findings from these NTP toxicology/carcinogenesis 2-year rodent studies of 7 commonly used herbs. In these studies, the individual herb or ...
Snow Stephanie J - - 2012
OBJECTIVES: To examine how the new concept of stroke as an emergency condition led to the development of new clinical pathways for stroke patients in Newcastle Upon Tyne, implemented through protocols which were then rapidly adopted across the UK and further afield. METHODS: Historical analysis using health policy documents, published ...
Mas Sergi - - 2012
The successful application of pharmacogenetics in routine clinical practice is still a long way from becoming a reality. In order to favor the transfer of pharmacogenetic results to clinical practice, especially in psychiatry, these studies must be optimized. This article reviews the strengths and weaknesses that characterize pharmacogenetic studies in ...
Halperin Jonathan L - - 2012
Nonvalvular atrial fibrillation increases in prevalence with age and often requires long-term oral anticoagulation to prevent ischemic stroke. Vitamin K antagonists are highly effective for stroke prevention. However, suboptimal risk assessment, variability in response, drug and food interactions, and monitoring requirements result in underprescription of warfarin by physicians and poor ...
Lewis David H - - 2012
Stroke and cerebrovascular diseases are major causes of mortality, morbidity, and disability. Nuclear Medicine, primarily via tomographic methods, has made significant contributions to the understanding of the hemodynamic and metabolic consequences of cerebrovascular diseases. In this review, the findings in acute, subacute, and chronic cerebrovascular diseases are described. Many of ...
Demchuk Andrew M - - 2012
Constant efforts are being made in the stroke community to aim for maximum benefit from thrombolytic therapy since the approval of intravenous recombinant tissue plasminogen activator (rt-PA; alteplase) for the management of acute ischaemic stroke. However, fear of symptomatic haemorrhage secondary to thrombolytic therapy has been a major concern for ...
Lazzaro Marc A - - 2012
Guidelines have been established for the management of acute ischemic stroke; however, specific recommendations for endovascular revascularization therapy are lacking. Burgeoning investigation of endovascular revascularization therapies for acute ischemic stroke, rapid device development, and a diverse training background of the providers performing the procedures underscore the need for practice recommendations. ...
Zur Eyal - - 2012
Sodium cromoglicate (cromolyn sodium) is a very well-known medicine that has been used for many years for various allergic conditions. The topical use of this medicine is less known, and there are no commercial medicines of cream, gel, or lotion in most of the world. This article summarizes the clinical ...
Worm Boris B Biology Department, PO Box 15000, Dalhousie University, Halifax, NS, B3H 4R2, Canada. - - 2012
Recently, the global state of marine fisheries and its effects on ecosystems have received much scientific (and public) scrutiny. There is little doubt that global limits to exploitation have been reached and that recovery of depleted stocks must become a cornerstone of fisheries management. Yet, current trends appear to be ...
Srivastava Pooja - - 2012
Pluchea lanceolata (DC.) Oliv. & Hiern, (Family: Asteraceae) is a rapidly spreading perennial herb, considered valuable for the management of anti-inflammatory disease. Scientific reports dealing with phytochemical and pharmacological research and its traditional have been reviewed. Reports have also suggested that its prominent constituents viz. triterpenoids, sterols, flavonoids and lactones ...
Perry Jillian M - - 2012
This article addresses the recognition and management of acute ischemic stroke. It includes a discussion of cerebrovascular anatomy, common ischemic stroke syndromes, and central venous thrombosis. Extensive attention is paid to the initial emergency department management of stroke, addressing medical and systems issues, and treatment of ischemic stroke by thrombolysis.
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