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Lee Eugene W EW Virginia Mason Medical Center, Seattle, WA, USA, - - 2014
Mixed urinary incontinence is a commonly encountered condition for urologists, urogynecologists, and primary care providers. In this review, we discuss the approach to the evaluation and management of patients with simultaneous stress and urgency urinary incontinence. The available evidence for treatment modalities in the setting of mixed urinary incontinence is ...
Biffl Walter L WL Department of Surgery, Denver Health Medical Center/University of Colorado, 777 Bannock Street, MC 0206, Denver, 80204-4507, CO, USA, - - 2014
The optimal management of patients with penetrating abdominal injuries has been debated for decades, since mandatory laparotomy (LAP) gave way to the concept of "selective conservatism." A comprehensive literature review was performed and summarized. A proposed management guideline for patients with penetrating abdominal trauma was created. Indications for immediate laparotomy ...
Masoompour Seyed Masoom SM Shiraz University of Medical Sciences, Shiraz, - - 2014
To determine the level of adherence to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines, we compared our inpatient management of exacerbations of chronic obstructive pulmonary disease (COPD) to these guidelines. This cross-sectional descriptive study was conducted from January 2011 to April 2012 in a 360-bed teaching hospital ...
Franik Sebastian S Nijmegen Centre for Mitochondrial Disorders (NCMD) at the Amalia Children's Hospital, Radboudumc, P.O. Box 9101, 6500 HB, Nijmegen, The - - 2014
Despite major advances in understanding the pathophysiology of mitochondrial diseases, clinical management of these conditions remains largely supportive, and no effective treatment is available. We therefore assumed that the burden of disease combined with the lack of adequate treatment leaves open a big market for complementary and alternative medicine use. ...
Szymanski Konrad M KM Division of Pediatric Urology, Riley Hospital for Children at Indiana University Health, Indianapolis, IN. Electronic address: - - 2014
Early Malone antegrade continence enema (MACE) complications are rare, but can be devastating, particularly if they involve loss of the channel. Management of these complications is not well described. We report on a patient who had her MACE channel successfully salvaged in the immediate postoperative period using a colonoscopic retrograde ...
Schultz Corinna L CL Children's Hospital of Philadelphia, Philadelphia, Pennsylvania2currently with Alfred I. duPont Hospital for Children, Wilmington, - - 2014
In 2011, the American Society of Hematology (ASH) published updated guidelines for the management of childhood immune thrombocytopenia (ITP) recommending management with observation alone when there are mild or no bleeding symptoms, regardless of platelet count. Little is known about practice patterns of newly diagnosed ITP in the United States. ...
Pearce J J University of Edinburgh Medical School, Edinburgh, UK - - 2014
We undertook a retrospective case note review of our monthly multi-speciality penile dermatoses clinic (which includes clinicians from Genitourinary medicine, Dermatology and Urology), to examine conditions presenting to the service, and compare clinical management and outcomes with other similar services in the UK. Over the 3-year study period, 226 patients ...
Fleet J J Department of Ageing and Health,Guy's and St. Thomas' Hospital Foundation Trust,Westminster Bridge Road,London,SE1 - - 2014
ABSTRACT Background: Delirium is a major cause of morbidity and mortality amongst hospital patients. Previous studies have shown that it is often poorly recognized and managed. We wanted to assess the impact of a multifaceted intervention on delirium management. Methods: A pre/post-intervention design was used. The local hospital delirium guideline ...
Fierro Julie L JL Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, - - 2014
Objective. To compare practice patterns regarding the diagnosis and management of streptococcal pharyngitis across pediatric primary care practices. Design. Retrospective cohort study. Setting. All encounters to 25 pediatric primary care practices sharing an electronic health record. Methods. Streptococcal pharyngitis was defined by an International Classification of Diseases, Ninth Revision code for acute pharyngitis, positive ...
Prichard David D Clinical Enteric Neuroscience Translational and Epidemiological Research Program, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 1st Street, Rochester, MN, 55905, USA, - - 2014
Defecatory disorders (DD) and fecal incontinence (FI) are common conditions. DD are primarily attributable to impaired rectoanal function during defecation or structural defects. FI is caused by one or more disturbances of anorectal continence mechanisms. Altered stool consistency may be the primary cause or may unmask anorectal deficits in both ...
- - 2014
THE GOVERNMENT has been criticised by MPs for its lack of urgency in preventing deaths from sepsis. An estimated 37,000 patients in England die of the condition every year because of failings such as delayed examination and inadequate record taking.
Sprinks Jennifer - - 2014
OVERCROWDING IN emergency departments (EDs) must be addressed urgently to ensure patients waiting to be admitted to wards are not put at risk, the College of Emergency Medicine (CEM) has warned.
Patel Lina L Pediatric Emergency Medicine Attending, Assistant Professor, Department of Pediatrics, Division of Pediatric Emergency Medicine, Children's Mercy Hospital & Clinics, University of Missouri-Kansas City, Kansas City, - - 2014
Fingertip crush injuries are common hand injuries in children and often are evaluated initially in an emergency department. Nail bed injuries can be classified into subungual hematomas, simple or stellate lacerations, crush injuries, and avulsions. Emergency department physicians with good knowledge of fingertip anatomy can appropriately manage these injuries so ...
Elgendy Hamed H Department of Anesthesia, King Abdullah Medical City, Makkah, Kingdom Saudi Arabia; Assiut University Hospital, Assiut, Egypt, - - 2014
Tracheobronchial injury (TBI) may lead to catastrophe if remains undetected or managed improperly. The incidence of TBI is less in children as compared with adults due to their pliable chest wall. Its clinical manifestations include persistent pneumothorax, cervical subcutaneous emphysema, pneumomediastinum, cyanosis, and respiratory insufficiency. The recommended airway management is ...
Block Stan L - - 2014
Patients presenting with cervical lymphadenitis are a complex and common occurrence in a general pediatric practice. Although Staphylococcus aureus (often methicillin-resistant S. aureus [MRSA]) and Streptococcus pyogenes predominate as causative pathogens, the next most common pathogens, Bartonella, atypical mycobacterium, and mononucleosis, also must be considered early on. The best way ...
Tomashek Kay M KM Dengue Branch, Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, San Juan, Puerto - - 2014
Dengue is a major cause of morbidity in Puerto Rico and is well-known to its physicians. Early case identification and timely initiation of treatment for patients with severe dengue can reduce medical complications and mortality. To determine clinical management and reporting practices, and assess knowledge of dengue and its management, ...
Bibby Anna C AC Academic Respiratory Unit, North Bristol NHS Trust, Southmead Hospital, - - 2014
Chyle leaks occur when there is interruption to the lymphatic ducts that transport chyle around the body. The loss of this protein-rich, calorie-rich fluid can cause serious complications including dehydration, malnutrition and immunosuppression. Treatment of chyle leaks depends on the underlying cause, which may be surgical, secondary to malignant invasion ...
Lefebvre D D The Royal (Dick) School of Veterinary Studies and Roslin Institute, University of Edinburgh, Easter Bush Veterinary Centre, Easter Bush, Roslin, Midlothian EH25 9RG, - - 2014
There is a need for an improved understanding of equine postoperative ileus (POI), both in terms of clinical definition and optimal management. Although the pharmacological strategies that are used to treat POI continue to evolve, little is known about the supplementary strategies used to prevent and manage this condition. To ...
Shiota Takako - - 2014
Cognitive impairment is one of the side effects of using anticholinergic medicines for overactive bladder; however, its incidence has not been fully reported. We experienced two elderly Japanese patients with overactive bladder who had temporary cognitive impairment caused by anticholinergic medicines. The first case was a 79-year-old female patient to ...
Voss Sarah S Faculty of Health and Applied Sciences, University of the West of England, Bristol, UK. Electronic address: - - 2014
The best method of initial airway management during resuscitation for out of hospital cardiac arrest (OHCA) is unknown. The airway management techniques used currently by UK paramedics during resuscitation for OHCA are not well documented. This study describes the airway management techniques used in the usual practice arm of the ...
Arriola Edurne E Department of Medical Oncology, Hospital del Mar, Passeig Marítim 25-29, 08003 Barcelona; IMIM (Institut Hospital del Mar d'Investigacions Mèdiques), Dr Aiguader 88, 08003 Barcelona, - - 2014
Afatinib is an irreversible ErbB family blocker tyrosine kinase inhibitor (TKI), which has recently been approved for the treatment of patients with EGFR M+ non-small cell lung cancer. As observed with reversible EGFR TKIs, it can induce class-effect adverse events. Appropriate management of afatinib-related adverse events improves quality of life ...
Sayegh Eli T ET Department of Orthopaedic Surgery, Columbia University Medical Center, 630 West 168th Street, New York, 10032-3784, NY, USA, - - 2014
The optimal management of olecranon bursitis is ill-defined. The purposes of this review were to systematically evaluate clinical outcomes for aseptic versus septic bursitis, compare surgical versus nonsurgical management, and examine the roles of corticosteroid injection and aspiration in aseptic bursitis. The English-language literature was searched using PubMed, Cumulative Index ...
Jeyaruban Andrew A Faculty of Medicine, James Cook University, Townsville, Queensland, Australia, - - 2014
This systematic review aims to summarise published evidence that assessed the management of gout in regard to the following: prescription of urate lowering therapy (ULT), monitoring of serum urate levels (sUA) and allopurinol dosing in patients with renal impairment, lifestyle advice and acute management of gout. Studies investigating the management ...
Banayosy Aly El AE Departments of 1Surgery and 2Medicine, Heart and Vascular Institute, Penn State Milton S. Hershey Medical Center, Penn State College of Medicine, Hershey, PA, - - 2014
Left ventricular assist devices (LVADs) have become more important in the management of patients with advanced heart failure. New generation rotary blood pumps demonstrated survival benefits and improved functional status and quality of life in these patients. Although a variety of relevant advances have been achieved in the field of ...
Baheti A D AD Department of Imaging, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Ave, Boston, MA 02215, USA; Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Electronic address: - - 2014
There is increasing focus on intrahepatic cholangiocarcinoma (IHCC) due to its rising incidence worldwide and relatively poor prognosis, with the revised TNM classification (2009) introducing a separate staging system for IHCC for the first time. In this article, we comprehensively review the current role of the radiologist in the diagnosis ...
Yachimski Patrick P Division of Gastroenterology Hepatology & Nutrition, Vanderbilt University Medical Center, Nashville, Tennessee, USA Division of Gastroenterology & Institute for Technology Assessment, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA - - 2014
Barrett's esophagus (BE) develops as a consequence of chronic esophageal acid exposure, and is the major risk factor for esophageal adenocarcinoma (EAC). The practices of endoscopic screening for-and surveillance of-BE, while widespread, have failed to reduce the incidence of EAC. The majority of EACs are diagnosed in patients without a ...
Mawet Jerome J Neurovascular Research Laboratory, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, MA, USA Emergency Headache Center, Lariboisiere Hospital, Assistance Publique-Hopitaux de Paris, France DHU NeuroVasc, - - 2014
Migraine, particularly with aura, increases the risk for ischemic stroke, at least in a subset of patients. The underlying mechanisms are poorly understood and probably multifactorial. We carried out an extended literature review of experimental and clinical evidence supporting the association between migraine and ischemic stroke to identify potential mechanisms ...
Valle Juan W JW University of Manchester, Manchester Health Sciences Centre and Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester M20 4BX, UK. Electronic address: - - 2014
Pancreatic neuroendocrine tumors (pNETs) are infrequent malignancies which manifest in both functional (hormone-secreting) and more commonly non-functional (non-secreting) forms. The oral multitargeted tyrosine kinase inhibitor sunitinib and mammalian target of rapamycin (mTOR) inhibitor everolimus are approved as targeted therapies for patients with well-differentiated, non-resectable disease and evidence of disease progression. ...
Katsuragi Shinji S Department of Obstetrics and Gynecology, Sakakibara Heart Institute, Fuchu, - - 2014
Abstract Objective: We have reported a 7-fold reduction in newborn umbilical arterial (UA) metabolic acidemia after adoption of a rule-based 5-category colour coded fetal heart rate (FHR) management framework. We sought evidence for the relationship being causal by detailed analysis of FHR characteristics and acid-base status before and after training. ...
Ruchlemer Rosa R Department of Hematology, Shaare Zedek Medical Center, 12 Shmuel Biet St., 91031, Jerusalem, Israel, - - 2014
Medicinal cannabis is an invaluable adjunct therapy for pain relief, nausea, anorexia, and mood modification in cancer patients and is available as cookies or cakes, as sublingual drops, as a vaporized mist, or for smoking. However, as with every herb, various microorganisms are carried on its leaves and flowers which ...
Whiteley Ian I Clinical Nurse Consultant in Stomal Therapy and Wound - - 2014
Protecting the perineum from faecal enzymes and preventing faeces from spreading to wounds has been a major challenge for nurses and doctors. Clinicians whose patients are at risk of faecal contamination of wounds have used various methods and many non-standard devices have been trialled, including: large French urinary catheters; rigid ...
Goldstein S S Center for Acute Care Nephrology, Nephrology and Hypertension, The Heart Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 7022, RILF2, Cincinnati, OH 45229, USA - - 2014
Standard treatment practice for the hypotensive patient with poor tissue perfusion is rapid volume resuscitation; in some scenarios, such as septic shock, this is performed with targeted goal-directed endpoints within 6 h of presentation. As a result, patients often develop significant positive fluid accumulation, which has been associated with poor ...
Beck K K Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, - - 2014
To describe a practical approach to the community management of treatment-resistant schizophrenia (TRS). A descriptive review of an approach to the assessment and management of patients with TRS, including the community titration of clozapine treatment, and a report of the management recommendations for the first one hundred patients assessed by ...
Kirby Donald F DF aCenter for Human Nutrition, Digestive Disease Institute bDepartment of Rheumatic and Immunologic Diseases, Orthopedics and Rheumatology Institute, Cleveland Clinic, Cleveland, Ohio, - - 2014
The gastrointestinal tract is the most common extra-cutaneous organ system involved with systemic sclerosis (SSc) affecting approximately 90% of patients. This review summarizes the recent advances in the evaluation and management of gastrointestinal manifestations of SSc. There is a growing body of evidence that uncontrolled GERD can play a significant ...
Hahner Stefanie S Dept of Medicine I, Endocrinology and Diabetology, University Hospital - - 2014
To evaluate current management time lines in adrenal crisis (AC) and to establish time targets and limits for emergency treatment. Patients from a prospective study who had reported an AC (n=46) were contacted and asked about management of their AC. A survey among 24 European endocrinologists collected expert recommendations concerning ...
Haas T T Department of Anaesthesia, University Children's Hospital Zurich, Steinwiesstrasse 75, 8032 Zurich, Switzerland - - 2014
Summary Standard laboratory coagulation tests (SLTs) such as prothrombin time/international normalized ratio or partial thromboplastin time are frequently used to assess coagulopathy and to guide haemostatic interventions. However, this has been challenged by numerous reports, including the current European guidelines for perioperative bleeding management, which question the utility and reliability ...
Wilder C C Emergency Department, Huddersfield Royal Infirmary, Acre Street, Lindley, Huddersfield HD3 3EA, UK. Electronic address: - - 2014
The prevalence of asthma has been rising, particularly in younger age groups. In the 12-month period from February 2012 there were 28 deaths due to asthma in children under 18 in the United Kingdom, the majority of which were preventable. The purpose of this audit was to determine how effective ...
Anderson Jennifer L JL Integrated Research and Development Laboratory, Marshfield Clinic Research Foundation, Marshfield, Wisconsin, - - 2014
The disease burden and impact of canine blastomycosis in Wisconsin is uncertain. We surveyed small-animal veterinary practices to obtain estimates of disease incidence, determine patient outcomes, and investigate variation in diagnostic and treatment strategies used by veterinarians. Veterinarians representing small-animal practices in Wisconsin were contacted by mail with the option ...
Viverito Kristen - - 2014
This study examined the extent to which patients found to have clinically significant hyperglycemia after beginning a new antipsychotic receive guideline concordant management. This retrospective cohort analysis (N=403) used U.S. Department of Veterans Affairs databases and multivariable logistic regression models to examine the association of patient characteristics with the likelihood ...
Montgomery-Cranny Jodie J Dr Specialist Registrar in Oral Medicine in the Department of Oral Medicine, Charles Clifford Dental - - 2014
Dry mouth can be disabling for the patient and challenging for the clinician to manage. Xerostomia is the subjective perception of oral dryness whereas salivary hypofunction is an objectively measured decrease in whole saliva production. Management includes saliva substitutes and stimulants which may only give partial symptom relief.
Barr Susan S Division of Urogynecology, Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, 4301 West Markham, Slot 518, Little Rock, AR 72205, USA. Electronic address: - - 2014
Interstitial cystitis is a diagnosis of exclusion. The definition has expanded over the years to encompass painful bladder syndrome. It is disease state that is often delayed in its diagnosis and difficult to manage. Treatment options include oral and intravesical therapies as well as both minor and major surgical options. ...
Eastwood Glenn M GM Department of Intensive Care, Austin Hospital, Melbourne, VIC, Australia. - - 2014
Intensivists frequently prescribe proton pump inhibitors (PPIs) or histamine-2 receptor blockers (H2RBs) to intensive care unit patients for stress ulcer prophylaxis (SUP). Despite the common use of SUP medicines, there is limited high-level evidence to support the choice between them. To describe self-reported practice of SUP by Australian and New ...
Williams Lance A LA 3rd Department of Pathology, University of Alabama at Birmingham, 619 19th Street South, WPP230F, Birmingham, AL 35249-7331, USA. Electronic address: - - 2014
Every year, new studies are undertaken to address the complex issue of periprocedural management of patients on anticoagulants and antiplatelet medications. In addition, newer drugs add to the confusion among clinicians about how to best manage patients taking these agents. Using the most recent data, guidelines, and personal experience, this ...
Kannai Ruth R Hebrew University, Hadassah School of Medicine, Jerusalem, Israel - - 2014
It finally happened to me: I was sued for malpractice by the family of a patient who had died suddenly. My inner turmoil in the aftermath of this traumatic event affected me deeply. While I was an experienced family doctor dedicated to patient-centered medicine, the event challenged my customary approach ...
Sant'anna Bruno S BS Programa de Pós-Graduação em Aquicultura e Pesca, Instituto de Pesca do Estado de São Paulo, São Paulo, SP, - - 2014
The mangrove crab Ucides cordatus is one of the most exploited crustaceans in Brazil. The present study investigated the breeding season of this species and the period of the "andada" phenomenon, when the crabs are active outside their burrows and perform agonistic behaviors. Furthermore related them to environmental factors, in ...
Lau Dennis H DH Centre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, University of Adelaide and Royal Adelaide Hospital, Adelaide, - - 2014
Recent studies have highlighted significant variations in the management of recent-onset sustained atrial fibrillation (AF). We aim to provide a succinct and clear management algorithm for physicians treating patients with recent-onset sustained AF. We performed a comprehensive search of the literature on the management of recent-onset sustained AF with focus ...
Sandeep P P Department of Nephrology, SVIMS, Tirupati, Andhra Pradesh, - - 2014
We present a patient of who ingested large dose of of atenolol and amlodipine and was treated successfully with continuous venovenous hemodiafiltration. Early recognition of indications for renal support and early initiation of the same is the key to successful management.
X Quan Xiaohong X The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, - - 2014
Atopic dermatitis (Atopic dermatitis, AD) is a kind of chronic recurrent dermatitis. So far, no curative treatment has been found yet. Acupuncture, as a kind of alternative medicine, Flying Needle is a kind of acupuncture, which has a unique curative effectiveness in improving the skin lesion and itch. A single-center, ...
Grzybowski Andrzej - - 2014
Albrecht Scholz (Figure 1) was born in Görlitz (now Zgorzelec, a city located at the Polish-German border, covering both sides of the River Nysa) on September 6, 1940, the youngest of three children. His father was a laryngologist, specializing in voice and hearing impairment. Scholz attended school in his hometown ...
Alyami Fahad F Division of Pediatric Urology, Department of Surgery, University of Toronto; The Hospital for Sick Children, Toronto, - - 2014
Uroflowmetry (UF) is frequently employed in daily pediatric urology practice for diagnostic and follow-up purposes. We assess the utility and cost-effectiveness of UF in the management of patients seen at a tertiary care centre. We retrospectively reviewed the charts of consecutive patients who had a UF between January 1, 2010 ...
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