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Frese Richard C - - 2013
Self-insured healthcare entities should take the following steps to understand, report, and control their exposure to workers' compensation losses: Focus on safety and risk management. Maintain a proper retention. Create'skin in the game" through an allocation. Benchmark the program's performance. Perform frequent analyses and obtain second opinions.
- - 2013
Fellows of the American College of Obstetricians and Gynecologists may choose to limit the scope of their practices to gynecology and, accordingly, may choose not to carry professional liability coverage for obstetrics. The American College of Obstetricians and Gynecologists considers early pregnancy care to be within the scope of gynecology ...
Frese Richard C - - 2013
A healthcare finance leader can guarantee recognition of his or her organization's insurance program and better manage the program's liability by discussing changes in the following areas with an actuary: Claims management. Exposure. Coverage or retention Financial reporting of losses. Management goals. Other insurance and operational matters.
Wallis Laura - - 2013
Recognition by reimbursement and insurance companies remain key issues.
Sinnott Sarah-Jo - - 2013
Copayments are intended to decrease third party expenditure on pharmaceuticals, particularly those regarded as less essential. However, copayments are associated with decreased use of all medicines. Publicly insured populations encompass some vulnerable patient groups such as older individuals and low income groups, who may be especially susceptible to medication non-adherence ...
Sorrel Amy Lynn - - 2013
The end of the 2013 session of the legislature marked the beginning of new leadership at the Texas Department of Insurance (TDI) as Gov. Rick Perry appointed Julia Rathgeber to the helm of the agency in late May. The Senate unanimously confirmed that appointment in June. In an interview with ...
Liu Yongsheng - - 2012
Based on Hippocrates' pangenetic idea, Darwin elaborated his Pangenesis hypothesis to explain a host of phenomena including inherited diseases. The conventional wisdom is that Pangenesis is wrong because it explains the inheritance of acquired characteristics and no evidence was found to support his hypothetical gemmules - molecular carriers of hereditary ...
Fujioka Masahiko - - 2012
Therapeutic effects through G protein-coupled receptors (GPCRs) are promoted by a full agonist, partial agonist, neutral antagonist or inverse agonist. Dramatic change of function such as from a neutral antagonist to a full agonist with minimal variation of ligand structure is a phenomenon that medicinal chemists often encounter. This is ...
Suzuki Hajime - - 2012
Kampo, a form of traditional herbal medical practice, has become a substance of interest for scientific research. Although earlier clinical reports concerning Kampo are abundant, the scientific investigation of Kampo has a very short history. However, the process of acquiring quantifiable clinical trial evidence on herbal medicine is now clearly ...
Yao Chun - - 2012
In spite of the impressive progress in the investigation of hepatic encephalopathy (HE), the complex mechanisms underlying the onset and deterioration of HE are still not fully understood. Currently, none of the existing theories provide conclusive explanations on the symptoms that link liver dysfunction to nervous system disorders and clinical ...
Spong Catherine Y - - 2012
This month, we focus on current research in maternal-fetal medicine. Dr. Spong discusses six recent publications, and each is concluded with a "bottom line" that is the take-home message. The complete reference for each can be found in Box 1 on this page, along with direct links to the abstracts.
Handorf Charles R - - 2011
Molecular medicine is rapidly changing the diagnosis and management of cancer of unknown primary. The science, business, and economics of the genomic revolution have moved at such a pace that coordinating practical application of all available tools, such as gene expression analysis and immunohistochemistry, often seems to clash. In fact, ...
Wang Hongtao - - 2011
Pericarpium Citri Reticulatae and Citri Unshius Pericarpium are important Oriental medicinal materials used in many prescriptions. Among the Citrus species, the dried peels of C. japonica, C. maxima, and C. trifoliata are found to be adulterants and substitutes of Pericarpium Citri Reticulatae and Citri Unshius Pericarpium. In order to develop ...
Zhang Xiuli - - 2011
The herbalome is a project with the objective of globalizing Chinese herbal medicine (CHM) by clarification of its composition, structure, and function; by establishing a standard resource library; and by interpreting the synergistic and complementary mechanisms of multi-components on multi-targets. In phase I, it focuses on the development of systematic ...
- - 2011
The pharmaceutical industry is facing numerous, well-documented challenges - from the effects of patent expirations to high attrition rates in the drug-development pipeline. Future Medicinal Chemistry has invited a group of leaders from academia and industry to express their views on where the industry is heading and speculate as to ...
Pérez-Monté Juan E - - 2011
This article discusses the regulations and requirements of the U.S. Nuclear Regulatory Commission pertaining to the practice of nuclear medicine. Among the regulations and requirements to be discussed include the record keeping requirements and the information to be made available to the U.S. NRC regularly and during inspections. Also examined ...
Cohen Burton J - - 2011
Evidence-based practice (EBP) has emerged as an alternative to traditional social work practice and has ignited a new round in the decades-old debate about the relationship between knowledge and practice in the field. This article identifies several limitations inherent in the EBP perspective and argues that it would be unfortunate ...
McConnell Charles R - - 2011
As part of his or her role in preparing a departmental budget, a manager must often become involved in budgeting for capital expenditures, those purchases that are of a type and sufficient dollar value to be capitalized and depreciated. Depending on the value of a proposed purchase, the department manager ...
Núñez-Vergara L J - - 2011
Chromenopyridines constitute a structurally diverse class of compounds with a wide range of bioactivities and increasing presence in drugs. Here we analyze the scope of the synthetic methodology to access this nucleus with emphasis on multicomponent reactions and robust methodologies. Reactivity issues, medicinal applications and other properties are also reviewed.
Sarris Jerome - - 2011
The field of genetics, which includes the use of 'omic' technologies, is an evolving area of science that has emerging application in phytotherapy. Omic studies include pharmacogenomics, proteomics and metabolomics. Herbal medicines, as monotherapies, or complex formulations such as traditional Chinese herbal prescriptions, may benefit from omic studies, and this ...
Piotti A - - 2012
The study of the dispersal capability of a species can provide essential information for the management and conservation of its genetic variability. Comparison of gene flow rates among populations characterized by different management and evolutionary histories allows one to decipher the role of factors such as isolation and tree density ...
Heim Hans-Karl - - 2011
In the EU, a regulatory framework has been established which defines general conditions for marketing authorisation approval of similar biological medicinal products (SBMPs). In addition, the framework provides product-class specific recommendations for non-clinical evaluation of specific SBMPs containing as active substance recombinant somatropin, granulocyte-colony stimulating factor (G-CSF), erythropoietin, interferon alpha, ...
McCabe Linda L - - 2011
As the cost of whole genome analysis decreases, we have the opportunity to explore the interactions of various gene changes in an individual that lead to their particular phenotype. This will provide the ability to move from the epidemiologic study of groups, in which, the individuals are treated collectively and ...
Dickenson Donna L - - 2011
Whilst India has been debating how to regulate 'surrogacy' the UK has undergone a major consultation on increasing the amount of 'expenses'paid to egg 'donors', while France has recently finished debating its entire package of bioethics regulation and the role of its Biomedicine Agency. Although it is often claimed that ...
Vacca Caludia - - 2011
To suggest a scheme of decision making on pricing for medicines that are part of Free Regulated Regime, a regulation way of the pharmaceutical pricing policy in Colombia. It includes two regulation tools: international reference prices and a cost minimization analysis methodology. Following the current pricing policy, international reference prices ...
Kugler Eileen C - - 2011
A recent report from the Institute of Medicine of the National Academies (IOM) calls for states to amend regulations on the practice of advanced practice registered nurses (APRNs). This article reviews the roles of APRNs, the IOM recommendations, and efforts by national and state stakeholders to remove legal barriers to ...
Lambert Trevor - - 2011
The percentage of newly qualified doctors in the UK who want a career in general practice declined substantially in the 1990s. The English Department of Health expects that half of all doctors will become GPs. To report on choices for general practice made by doctors who qualified in 2000, 2002, ...
Sarwat Maryam - - 2011
Plant based medicines have gained popularity worldwide due to their almost negligible side effects. In India, the three traditional medicinal systems, namely homeopathy, Ayurveda and Siddha rely heavily on plants for medicinal formulations. To prevent the indiscriminate collection of these valuable medicinal plants and for their proper authentication and conservation, ...
Chen Shilin - - 2011
In recent years, genomics has developed rapidly with the application of next-generation sequencing technology. However, very few studies have been carried out on genomics for medicinal plants. This paper introduces the genome research of medicinal plants, including genome sequencing, assembly, annotation, and functional genomics, to set up the foundation for ...
Laing Rachel E - - 2011
Over 10 million SNPs have been discovered to date as the result of both a private and public effort in the past two decades. Extensive investigations on SNPs have been performed to assess clinical applications for pharmacogenomics and Personalized Medicine. Recently, around the 10(th) anniversary of the first publication by ...
Fernald Guy Haskin GH Biomedical Informatics Training Program, Stanford University School of Medicine, Department of Bioengineering, Stanford University, Stanford, CA, - - 2011
Widespread availability of low-cost, full genome sequencing will introduce new challenges for bioinformatics. This review outlines recent developments in sequencing technologies and genome analysis methods for application in personalized medicine. New methods are needed in four areas to realize the potential of personalized medicine: (i) processing large-scale robust genomic data; ...
Agrawal Varun - - 2011
Many patients with chronic kidney disease (CKD) receive care from primary care physicians. Identification and management of CKD complications in primary care is suboptimal. It is not known if current residency curriculum adequately prepares a future internist in this aspect of CKD care. We performed an online questionnaire survey of ...
Agel J - - 2011
Background Published data has demonstrated that collegiate athletes sustain significantly higher game than practice injury rates (13.8 vs 4.0 injuries per 1000 A-Es). Review of this data demonstrates disparities within the practice injury rates with pre-season practice injury rates being significantly higher than in-season and post-season practice rates. Objective Our ...
Rosen Rachel - - 2011
Multichannel intraluminal impedance with pH (pH-MII) has become the criterion standard test for the evaluation of gastroesophageal reflux disease, but it is not clear whether the results of this test change clinical decision making. The goal of the present study was to determine the differences in clinical decision making by ...
Pettker Christian M - - 2011
Patient safety is currently a critical focus within obstetrics. Standardization of intrapartum management, in particular with regard to fetal heart rate monitoring assessment and management, is an important effort to improve obstetrical adverse outcomes. This study explores various strategies to implement standardization of assessment and management. Such measures can impact ...
Miller David A - - 2011
Recent advances in standardized fetal monitoring nomenclature and interpretation make it possible to construct a standardized approach to intrapartum fetal heart rate management that is evidence-based and reflects consensus in the literature.
Barber James T JT - - 2011
Placenta percreta is a complication of pregnancy with significant morbidity and mortality rates. Conservative management may be considered when fertility preservation is desired or to possibly reduce morbidity when there is invasion of pelvic structures. We present 3 cases of antenatally diagnosed placenta percreta that were managed conservatively. A finding ...
Ruetzler Kurt - - 2011
INTRODUCTION: Endotracheal intubation (ETI) is the most widespread method for emergency airway management. Several studies reported that ETI requires considerable skill and experience and if performed incorrectly, may result in serious adverse events. Unrecognized tube misplacement or oesophageal intubation is associated with high prehospital morbidity. This study investigates the usability ...
Planchenault Dominique - - 2011
For hundreds of years, intuitively or deliberately, farmers and breeders have taken advantage of the slow and constant renewal of genetic diversity in their domesticated plants or animals. Their management efficiently combines selection to maintain existing varieties or breeds and selection to extract new biological items meeting incoming necessities and ...
Kemper Alex R AR Duke University, Durham, NC 27705, USA. - - 2011
Staphylococcus aureus is a common cause of skin abscesses. To evaluate primary care pediatricians' management of skin abscesses. A national mail survey of a random sample of 385 general pediatricians conducted from April to June 2010. The response rate was 49%. Most respondents (72%) were aware that the Centers for ...
Harris Tim - - 2011
There is conflicting evidence concerning the role and safety of prehospital intubation, and which providers should deliver it. Success rates for physician-performed rapid sequence induction are reported to be 97-100%, with limited evidence of improved survival in some patient groups. However, there is also evidence that prehospital intubation and ventilation ...
Wadelius Mia - - 2011
A report on the 9th Annual Cold Spring Harbor/Wellcome Trust meeting 'Pharmacogenomics and Personalized Medicine', Hinxton, Cambridge, UK, 29 September to 2 October 2011.
Kirsten Toralf - - 2011
Ontologies are increasingly used to structure and semantically describe entities of domains, such as genes and proteins in life sciences. Their increasing size and the high frequency of updates resulting in a large set of ontology versions necessitates efficient management and analysis of this data. We present GOMMA, a generic ...
Niu Linhai - - 2011
Poor quality control of medicinal herbs has led to instances of toxicity, poisoning and even deaths. The fundamental step in quality control of herbal medicine is accurate identification of herbs. Array-based techniques have recently been adapted to authenticate or identify herbal plants. This article reviews the current array-based techniques, eg ...
Hashizume Makoto - - 2011
Although the incidence of bleeding from gastric varices is relatively low (10%-36%), the bleeding is massive once it has occurred and it increases the patient's mortality. The management of esophageal variceal bleeding is highly differentiated with several effective treatments available. In contrast, bleeding from gastric varices continues to be a ...
Hackney Charles H - - 2011
The motivational aspects of humor are considered from the perspective of terror management theory, testing the hypothesis that exposure to the mortality salience manipulation will result in an alteration in participants' appreciation of humorous material. Participants rated several comic strips, indicating how funny they found the jokes. The differential relevance ...
Guo Xiaorong - - 2011
Scutellaria baicalensis GEORGI (Lamiaceae) is the botanical origin of the well-known traditional Chinese medicine "Huang Qin" (Radix Scutellariae). Due to overexploitation that had induced a decline in natural sources, the dried roots of its congeners, S. amoena, S. rehderiana, and S. viscidula, have been used to adulterate it in recent ...
Marendaz Jean-Luc - - 2011
The present paper highlights a new safety management program, MICE (Management, Information, Control and Emergency), which has been specifically adapted for the academic environment. The process starts with an exhaustive hazard inventory supported by a platform assembling specific hazards encountered in laboratories and their subsequent classification. A proof of concept ...
Hsieh Hsin-Ying - - 2011
Epigenetics is a phenomenon of heritable changes in the chromatin structure of a genomic region, resulting in a transcriptional silent or active state of the region over cell mitosis. Mounting evidence has demonstrated phenotypic consequence of alternations in the patterns of DNA methylation and histone modifications, two of the well-studied ...
García-Sancho Miguel - - 2011
This paper explores the introduction of professional systems engineers and information management practices into the first centralized DNA sequence database, developed at the European Molecular Biology Laboratory (EMBL) during the 1980s. In so doing, it complements the literature on the emergence of an information discourse after World War II and ...
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