Cellular therapy is a novel form of medical or surgical treatment using cells in place of or in addition to traditional chemical drugs. The preparation of cellular products - called advanced therapy medicinal products - ATMP in Europe, requires compliance with good manufacturing practices (GMP). Based on long-term experience in ...

ABSTRACT: Currently most biomedical labs in universities and government funded research institutions use paper lab notebooks for recording experimental data and spreadsheets for managing sample data. One consequence is that sample management and documenting experiments are viewed as separate and distinct activities, notwithstanding that samples and aliquots are an integral ...

An interview with Stephen A. Felt, DVM, MPH, DACLAM, DACVPM, Attending Veterinarian, Assistant Professor, Department of Comparative Medicine, Associate Director, Veterinary Service Center, Director, Laboratory Animal Medicine Residency Program, Stanford University, Stanford, CA.

Little is known about the state of experimentation in the field of medicine during the Medieval Islamic era. With few exceptions, most of the contemporary sources on history of medicine propagate the idea that the roots of experimental medicine in its modern form, including clinical trials and drug-potency studies, first ...

BACKGROUND: The selective non-operative management of penetrating abdominal injury is gaining increasing acceptance. In Great Britain and Ireland, the management of trauma remains the responsibility of general surgeons. This study appraises the acceptance and utilisation of selective non-operative management strategies by British and Irish general surgeons, compared with trauma surgeons ...

: To describe the use of complementary alternative medicines in women with chronic vaginitis and to evaluate epidemiologic factors associated with these treatments. : In this prospective cohort study, patients with chronic vaginitis completed a questionnaire about past diagnoses and treatments. Information regarding demographics, medical and social history, perceived mental ...

This article reviews the management in emergency departments of acutely unwell patients with intestinal obstruction. It describes the diagnostic tests and management required for patients with this condition, suggests that reflecting on practice can help practitioners evaluate the quality of the care they gave and presents a case study involving ...

The aim of the study was to develop an improved management mode in Ämmässuo landfill (Finland) for leachate ammonium-nitrogen removal, to minimize the leachate management costs and secure compliance with the uptrend requirements of regulations for on-site leachate management. With a single sequential batch simulation reactor, the minimum C/N ratio ...

An interview with Gene M. Rukavina, AAS, RVT, RLATG, Training Manager, Division of Laboratory Animal Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA.

Objective: Hyperglycemia is often inadequately treated during hospitalization. To address this, we piloted a Targeted Glycemic Management (TGM) service with the goals of improving clinician awareness of available inpatient glycemic management protocols and improving responsiveness to and frequency of severe hyperglycemia.Methods: Patients with a blood glucose (BG) ≥300 mg/dL who ...

A practical route to tertiary diarylmethylamides or -carbamates from imines, organozinc reagents and acyl chlorides or chloroformates is described. This route involves the formation of an imine, which is used without isolation, followed by its activation by the carbonyl-containing electrophile and the trapping of the acyliminium by an organozinc reagent. ...

Cuminum cyminum and Carum carvi are the sources of cumin and caraway seeds respectively, which have been used since antiquity for the treatment of various indications in traditional healing systems in wide geographical areas. Cumin and caraway seeds are rich sources of essential oils and have been actively researched for ...

To determine whether educational baby books are an effective method for increasing low-income, first-time mothers' safety practices during their child's first 18 months. Primiparous women (n = 167) were randomly assigned to 1 of 3 groups: an educational book group, a noneducational book group, or a no-book group. Home visits ...

The Guidelines to the Practice of Anesthesia Revised Edition 2011 (the guidelines) were prepared by the Canadian Anesthesiologists' Society (CAS), which reserves the right to determine their publication and distribution. Because the guidelines are subject to revision, updated versions are published annually. Whereas previous versions of the guidelines appeared as ...

Hypertension is a chronic condition that can be managed with self-monitoring, lifestyle changes, and medication. The purpose of this study was to describe receipt of physician's treatment advice and use of treatments to manage hypertension among Oklahoma's adult population. A random-digit-dialed telephone survey was administered to noninstitutionalized adult residents of ...

Anaphylaxis during anaesthesia is a rare event that in ∼60-70% of cases is secondary to neuromuscular blocking agents. It has been suggested previously that the recent introduction of sugammadex may provide a novel therapeutic approach to the management of rocuronium-induced anaphylaxis. We describe the case of a 33-yr-old female who ...

Veterinary directories from Canada's 4 western provincial veterinary associations provided source data for compiling demographic profiles of the veterinary profession for the years 1991, 1996, 2001, and 2007. From 1991 to 2007 the number of veterinary practitioners in western Canada increased by 1197 (79%), for a net gain of 75 ...

Huanglongbing is one of the most devastating diseases of citrus (Citrus spp.). One management tactic against huanglongbing is aggressive management of the vector, the Asian citrus psyllid (Diaphorina citri Kuwayama), with insecticide applications. However, D. citri in abandoned groves are not controlled and therefore pose a risk of reinfestation for ...

To assess the knowledge of mothers regarding commonly used Complimentary alternative medicines, their usage and various therapeutic choices for common ailments. A cross-sectional Survey on a predesigned proforma was done from July 2007- August 2007 in the out patient department of a tertiary care hospital. Consent was taken from the ...

Laser hair removal is a rapidly growing aesthetic procedure requested predominantly by women. At a time of falling reimbursement by payers, gynecologists have an opportunity to improve the fiscal health of their practices while delivering a service valued by their patients. As a result, practicing gynecologists should become acquainted with ...

The strategy of the nonfinancial audit is discussed, with specific information for the facial plastic and aesthetic surgeon. The author provides specific questions and a roadmap for the practitioner to follow to complete a nonfinancial audit to expose the strengths and weaknesses of their practice. This article discusses quality, productivity, ...

The purpose of our study was to determine how many radiology practices perform outside readings, what characteristics affect the prevalence and volume of outside readings, and how practices are paid for outside readings. We analyzed data from the American College of Radiology's 2007 Survey of Radiologists, a stratified random sample ...

To examine the gender differences in managing practice and staff members in orthodontic practices. All orthodontists in Virginia and Maryland (n = 427) were surveyed and demographic information was collected. For the crude analyses of the data, a Fisher's exact test or chi(2) test was performed. For the adjusted analyses, ...

In the increasingly competitive market of aesthetic surgery and the unstable predicament of the current economy, managing a successful aesthetic practice becomes ever more difficult. This article introduces the concept of Retailicine, combining essential elements of retail with the core principles of medicine. This new concept stresses the importance of ...

In searching for different patterns of practice, lifestyle, and environment supportive of optimal health, we look to our elders around the world, who in the wisdom that has sustained them, we learn from with careful attention. Thirty-seven elders who live by their traditions participated in the present study. They assisted ...

This article discusses about physicians and their practice in terms of a "brand" that is described as one's persona and unique traits. By developing and portraying the uniqueness and singularity of the physician and the practice, one becomes open and transparent to clients for greatest patient satisfaction. Along with some ...

Comparative analysis of epigenomes offers new opportunities to understand cellular differentiation, mutation effects and disease processes. But the scale and heterogeneity of epigenetic data present numerous computational challenges.

Intestinal failure manifests as diarrhoea, fluid and electrolyte imbalance and malabsorption caused due to surgical resection of small intestine or very rarely due to nonfunctioning of large segment of bowel. Management of short bowel syndrome is quite challenging which requires better understanding of the site and extent of resected segment, ...

Mortality rates vary widely among dialysis facilities even after adjustment with standardized mortality ratios (SMRs). This variation may occur because top-performing facilities use practices not shared by others, because the SMR fails to capture key patient characteristics, or both. Practices were identified that distinguish top- from bottom-performing facilities by SMR. ...

The Using Learning Teams for Reflective Adaptation (ULTRA) study used facilitated reflective adaptive process (RAP) teams to enhance communication and decision making in hopes of improving adherence to multiple clinical guidelines; however, the study failed to show significant clinical improvements. The purpose of this study was to examine qualitative data ...

Hiring for your practice is a big responsibility as well as a commitment of time and resources. To find and place the right person for an opening in your practice, consider all of the tools and methods available to you. Use the Internet to advertise the open position, do background ...

Long-term sustainment of improvements in care continues to challenge primary care practices. During the 2 years after of our Improving Depression Care collaborative, we examined how well practices were sustaining their depression care improvements. Our study design used a qualitative interview follow-up of a modified learning collaborative intervention. We conducted ...

The answer to the question, "Is autonomous practice in neurologic physical therapy defined differently based on the type of practice setting?" is no. Autonomous practice is a characteristic of the physical therapist, embodying excellence, communication and collaboration, and advocacy and caring. It is our belief that many physical therapists already ...

Small general practices are often perceived to provide worse care than larger practices. To describe the comparative performance of small practices on the UK's pay-for-performance scheme, the Quality and Outcomes Framework. Longitudinal analysis (2004-2005 to 2006-2007) of quality scores for 48 clinical activities. Family practices in England (n = 7502). ...

The purpose of this study was to compare Korean and European female professional golfer's reported practice hours and their different understandings about golf training. 55 Korean and 21 European female professional golfers were asked questions about average actual practice days per week, average actual practice hours per day, ideal practice ...

Within construction the masonry trade has particularly high rates of musculoskeletal disorders (MSDs). A NIOSH-sponsored meeting of masonry stakeholders explored current and potential "Best Practices" for reducing MSDs in masonry and identified potential regional differences in use of practices. To verify and better understand the regional effects and other factors ...

The expanding biotechnology landscape offers new intersections with traditional strengths in chemical biology.

This Classic Article is a reprint of the original work by Baron Joseph Lister, On the Antiseptic Principle in the Practice of Surgery. An accompanying biographical sketch of Baron Joseph Lister is available at DOI 10.1007/s11999-010-1319-3 . The Classic Article is (c)1867 and is reprinted with courtesy from Lister J. ...

The rise of new experimental techniques, such as high-throughput combinatorial methods, and the availability of large data sets by means of the Internet have greatly increased the amount of data that must be managed by relatively small projects. Scientific data management systems developed for large projects are often not available, ...

There are chances that the use of larger than recommended dose of Ayurvedic medicines containing aconite can produce drug reactions. Vatsanabha (Aconitum ferox Wall.) is a very well-known ingredient of Ayurvedic formulations and is prescribed as an antipyretic, analgesic, anti-rheumatic, appetizer and digestive. The recommended dose of purified Vatsanabha (A. ...

A poll was conducted at the 2009 Annual Meeting of the American Association of Hip and Knee Surgeons to determine current practices among its members in primary total hip arthroplasty and total knee arthroplasty. This article summarizes the audience responses to a number of multiple choice questions concerning perioperative management ...

The Maturity Matrix (MM) comprises a formative evaluation instrument for primary care practices to self-assess their degree of organisational development in a group setting, guided by an external facilitator. The practice teams discuss organisational development, score their own performance and set improvement goals for the following year. The objective of ...

BACKGROUND: WHO estimates that some 130 million women worldwide are affected, and every year another 2 million girls and young women are at risk of undergoing the practice of FGM. Although Nigeria has a prevalence of 19% in 2003,a reduction from 25% prevalence of 1999 national survey, it still has ...

In this qualitative study, African Americans described 3 orientations about spiritual practices and diabetes self-management: Spiritual practice as effort toward self-management; spiritual practice and self-management as effort toward healing; and spiritual practice as effort toward healing. Spiritual practices may influence diabetes self-management in African Americans and be a resource in ...

While practice-level or team accreditation is not new to primary care in the UK and there are organisational indicators in the Quality and Outcomes Framework (QOF) organisational domain, there is no universal system of accreditation of the quality of organisational aspects of care in the UK. To describe the development, ...

Deliberate practice-that is, engagement in activities specifically designed to improve performance in a domain-is strongly predictive of performance in domains such as music and sports. It has even been suggested that deliberate practice is sufficient to account for expert performance. Less clear is whether basic abilities, such as working memory ...

This study compared the effects of mental practice, physical practice, and no practice on the performance and retention of a novel throwing task. Research supports the effectiveness of mental practice on performance; however, retention of learning has not been adequately investigated. Participants were 152 students ages 18 to 44 years ...

To identify factors that are associated with the scope of practice of FPs and GPs who have office-based practices. Secondary univariable and multivariable analyses of cross-sectional data from the 2001 National Family Physician Workforce Survey conducted by the College of Family Physicians of Canada. Canada. General community of FPs and ...

A medical practice, whether operated by a solo physician or by a group, is a business. For a neurology practice to be successful, it must meet performance measures that ensure its viability. The best method of doing this is to benchmark the practice, both against itself over time and against ...

We conducted a field study in three primary care practices representing different practice types: a solo practice; a certified patient-centered medical home; and a multiphysician, multispecialty practice connected to a local university. All three practices shared a common culture in the way that practice members related to each other. In ...