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Ravera Silvia S Department of Pharmacotherapy and Pharmaceutical Care, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, the - - 2012
To illustrate (i) the criteria and the development of the DRUID categorization system, (ii) the number of medicines that have currently been categorized, (iii) the added value of the DRUID categorization system and (iv) the next steps in the implementation of the DRUID system. The development of the DRUID categorization ...
Medina Miguel Ángel - - 2013
Modern systems biology is already contributing to a radical transformation of molecular life sciences and biomedicine, and it is expected to have a real impact in the clinical setting in the next years. In this review, the emergence of systems biology is contextualized with a historic overview, and its present ...
Safkhani Masoumeh - - 2012
Recently, Chen et al. have proposed a novel tamper resistant prescription RFID access control system, published in the Journal of Medical Systems. In this paper we consider the security of the proposed protocol and identify some existing weaknesses. The main attack is a reader impersonation attack which allows an active adversary ...
Angmo Kunzes - - 2012
The Sowa-rigpa system of traditional healing has been practiced from time immemorial in western Ladakh but its existence is in jeopardy today. Lack of information on various aspects of this system such as treatment methods, materials used for medicine and socio-cultural aspects may affect the long-term survival of this system. ...
Auffray Charles - - 2012
This special issue on "Systems biology and personalized medicine" includes five complementary articles that highlight how functional genomics and computational physiology can contribute to the development of predictive, preventive, personalized and participatory (P4) medicine. Edited by Prof. Leroy Hood and Prof. Charles Auffray.
- - 2012
Cover illustration Focus: "Systems biology and personalized medicine". This focus issue of Biotechnology Journal is edited by Prof. Leroy Hood and Prof. Charles Auffray. We chose this cover to emphasize the participatory element of P4 (predictive, preventive, personalized and participatory) medicine, as participation from all of us is key in ...
Hood Leroy L Institute for Systems Biology, 401 Terry Avenue North, Seattle, WA 98109-5234, USA. - - 2012
Personalized medicine is a term for a revolution in medicine that envisions the individual patient as the central focus of healthcare in the future. The term "personalized medicine", however, fails to reflect the enormous dimensionality of this new medicine that will be predictive, preventive, personalized, and participatory-a vision of medicine ...
Blumenstein Benjamin - - 2012
The study aimed at the identification of favourable land use options for semi-natural grassland management and preservation. Economic assessments of energy recovery by the integrated generation of solid fuel and biogas from biomass (IFBB) in comparison with dry fermentation (DF) and hay combustion systems (HC), beef cattle production (BC) and ...
Delgado Fernando - - 2012
One of the fundamental advances of the transition of the Middle Ages to the Renaissance was the rediscovery of the Greek philosophers. Among the greatest representatives of this epoch we find the Cordovan doctor and philosopher Averroes (Ibn Rushd) who, with his commentaries on the works of Aristotle, brought a ...
Agazarian Yvonne M - - 2012
Abstract Systems-centered therapy (SCT) is derived from a theory of living human systems and practiced in individual and group therapy. Excerpts from an inpatient group illustrate how SCT norms, particularly functional subgrouping and the hierarchy of defense modification, are introduced within the first few minutes of an SCT group. The ...
Hood Leroy - - 2012
Systems biology and the digital revolution are together transforming healthcare to a proactive P4 medicine that is predictive, preventive, personalized and participatory. Systems biology - holistic, global and integrative in approach - has given rise to systems medicine, a systems approach to health and disease. Systems medicine promises to (1) ...
Nam Sejin - - 2012
Clinical documents embody professional clinical knowledge. This paper shows an effective clinical document template (CDT) production system that uses a clinical description entity (CDE) model, a CDE ontology, and a knowledge management system called STEP that manages ontology-based clinical description entities. The ontology represents CDEs and their inter-relations, and the ...
Blobel Bernd - - 2012
Comprehensive interoperability between distributed eHealth/pHealth environments requires that the systems involved are based on a common architectural framework and share common knowledge. The paper deals with the representation of systems by related ontologies. Therefore, the architectural principles ruling the system design and the interrelations of its components also rule the ...
Fieschi M - - 2012
To review the history of AI in Medicine in the 1980's, placing the SPHINX system in the context of other research in this field. Summarize the main systems for AI in medicine developed in the 1970-1980 decade and their relationship to the development of clinical decision-making and consultation systems The ...
Mendonca Satish - - 2012
Extracorporeal methods have been an integral part in the management of poisonings. The elimination of a drug or toxin by extracorporeal techniques (ECT) is governed by the properties of the toxin and the chosen extracorporeal therapy. The various ECT include hemodialysis, hemoperfusion, hemofiltration, continuous renal replacement therapy and peritoneal dialysis, ...
Mafimisebi Taiwo E - - 2012
Smallholder livestock farmers in Nigeria utilize traditional medicines derived from medicinal plants (PMs) for the maintenance of their animals' health. This study was designed to determine the PMs used in the study area and their level of utilization by livestock farmers, compare the level of utilization of PMs across the ...
Summergrad Paul - - 2011
The practice patterns and career paths of physicians who are double-boarded in medicine, family practice, or neurology and psychiatry are not well understood. Given increased attention to integrated medical and psychiatric care, these individuals may play an important role. To compare the practice patterns and career paths of physicians who ...
Chang Todd Pou-Yen - - 2011
Although seen less frequently than acetaminophen or salicylate poisoning, acute iron poisoning remains a dangerous threat, particularly to pediatric patients. Multiple factors-including legal and manufacturing practices-have changed the landscape of iron poisoning over the decades. Despite these changes, diagnosis and management of iron poisoning have minimally evolved, and the current ...
Efferth Thomas - - 2011
It is estimated that three quarters of the world population rely on herbal and traditional medicine as a basis for primary health care. Therefore, it is one of the most important and challenging tasks for scientists working in drug research to investigate the efficacy of herbal medicine, to dissect favorable ...
Fan K L - - 2011
To review the characteristics of the consultation about the management of mercury exposure and identify the controversial issues on the clinical management of individuals with a history of mercury exposure. Descriptive case series. Hong Kong Poison Information Centre, Hong Kong. Persons consulting the Hong Kong Poison Information Centre about individuals ...
Fallen R S - - 2011
The common bedbug (Cimex lectularius) is increasingly prevalent and a source of concern and questions for patients. In addition to a range of cutaneous presentations and potential for serious sequelae, bedbug bites cause significant psychological distress and create an economic burden associated with infestation control. Recognition of characteristic entomology, clinical ...
Singh P - - 2011
Patients with bronchopleural fistula present with specific airway management and ventilatory concerns, which makes the anaesthetic management of these patients challenging. Myasthenia gravis is another condition requiring specific anaesthetic management, with possible unpredictable delays in recovery. A combination of both these conditions in a patient makes management even more difficult. ...
Morris John S - - 2011
Silvanus Bevan was born in Swansea, South Wales, moved to London where he trained as an apothecary, and then in 1715 opened a business at Plough Court off Lombard Street in London. As a committed Quaker he was renowned for honesty and fair-trading and consequently he prospered. In the 1730s ...
Baron Christian - - 2011
Using the Burgess Shale controversies as a case-study, this paper argues that controversies within different domains may interact as to create a situation of "com- plicated intricacies," where the practicing scientist has to navigate through a context of multiple thought collectives. To some extent each of these collectives has its ...
Kinge Tonjock R - - 2011
Inhabitants of the Mount Cameroon region depend on the forest resources of the region for their livelihood, including the diverse use of macrofungi. With the increasing loss of forest due to exploitation and urbanization, they are liable to rapidly lose their indigenous knowledge of the forest resources, especially of mushrooms. ...
Souza Marcy J - - 2011
Numerous analgesics are available for use in animals, but only a few have been used or studied in zoologic species. Tramadol is a relatively new analgesic that is available in an inexpensive, oral form, and is not controlled. Studies examining the effect of tramadol in zoologic species suggest that significant ...
Gunturu Krishna S - - 2011
Although the majority of published cases of lead poisoning come from occupational exposures, some traditional remedies may also contain toxic amounts of lead. Ayurveda is a system of traditional medicine that is native to India and is used in many parts of world as an alternative to standard treatment regimens. ...
Chukwuocha Uche - - 2011
This study was carried out to rapidly access the practice of home management of malaria by caregivers and community health workers in a rural part of South Eastern Nigeria between March and October, 2010. Structured, pretested questionnaires, focus group discussions and oral interviews were used to collect data from 300 ...
Karjalainen Oskari K - - 2011
Herein a practical and scalable route to 1-deoxyaltronojirimycin is presented. The target is achieved in 9 steps and 43% yield featuring only two chromatographic purifications.
Doggrell S A - - 2010
Increasing adherence to medicines should improve glycaemic control and be cost effective in patients with Type 2 diabetes. It is assumed that the intervention of an allied health professional will improve adherence to medicines, but this has not been well documented. The aim of this review was to determine whether ...
Field Emma - - 2010
Gonorrhoea is the second most common notifiable sexually transmissible infection (STI) in Queensland. Notifications have been increasing since 2002. Enhanced surveillance was undertaken in this study in order to evaluate clinical management and add to understanding of the epidemiology of gonorrhoea and in South East Queensland. Information on clinical management ...
Silva-Lima Beatriz - - 2010
A workshop organised by the European Medicines Agency involved assessors and experts present in a Nonclinical Working Group evaluating juvenile animal studies for Paediatric Investigation Plans in collaboration with the Paediatric Committee and the Safety Working Party of the Committee for Human Medicinal Products. The objective of the workshop was ...
Kotlyar Michael - - 2011
Smokeless, spitless tobacco products are being introduced and marketed as cigarette substitutes. Data are needed regarding how smokers interested in cessation would use these products, the levels of resultant toxicant exposure, and the feasibility of using these products as aids for tobacco cessation. Smokers were randomized to receive Camel Snus ...
Osei-Assibey G - - 2010
Minority ethnic/non-White populations are more prone to weight gain and more susceptible to obesity-related complications. The objective of this study was to systematically review dietary and lifestyle interventions for weight management in minority ethnic groups. Electronic databases and reference lists of original studies and reviews were searched for studies on ...
Hirsche Robert C - - 2011
Purpose. The purpose of this study was to explore the experience of people with neurological conditions who take the chronic disease self-management (CDSM) programme. The CDSM programme is used to teach skills to manage chronic conditions, and prevent secondary conditions. Few studies have explored the use of the CDSM programme ...
Abiola A O - - 2010
Domestic refuse remains a major environmental concern in large cities around the world. Its management also continues to be a major challenge. The aim of this study was to assess the effect of health education on the knowledge, attitude and practices of domestic refuse management (DRM) among community members in ...
Gleicher Norbert - - 2010
Medical care should be based on best available evidence. While randomized controlled trials (RCT) are currently considered a gold standard of study design, they are not always available and do not represent the only study format that can lead to best available evidence. This communication argues that overvaluation of RCT ...
Bergsieker Hilary B - - 2010
Pervasive representations of Blacks and Latinos as unintelligent and of Whites as racist may give rise to divergent impression management goals in interracial interactions. We present studies showing that in interracial interactions racial minorities seek to be respected and seen as competent more than Whites do, whereas Whites seek to ...
Fleskens Stijn A J H M - - 2010
OBJECTIVES/HYPOTHESIS: To investigate the current clinical management of laryngeal mucosal premalignant lesions (LMPLs) among otorhinolaryngologists working in university hospitals (tertiary referral centers) and nonuniversity hospitals (secondary referral centers) in The Netherlands. Then to compare the investigated practice with the results published in the literature. STUDY DESIGN: Cross-sectional study. METHODS: A ...
Reagan Janet Thompson - - 2010
A national study of radiologic technologists' radiation safety practices in 2003 documented poor compliance. In addition, the 2003 study found that years of work experience and length of employment at a work site were significantly related to adherence with safety practices. The current study is a refinement and extension of ...
Tong Allison - - 2011
Non-adherence to medication regimens after kidney transplantation is a major risk factor for acute rejection and graft loss, yet little is known about the perspectives of kidney transplant recipients on medicine taking. This study aimed to describe the beliefs, experiences and perspectives of kidney transplant recipients on medicine taking. We ...
Alexander Janice - - 2010
Sudden Oak Death has been impacting California's coastal forests for more than a decade. In that time, and in the absence of a centrally organized and coordinated set of mandatory management actions for this disease in California's wildlands and open spaces, many local communities have initiated their own management programs. ...
Sklenicka Petr - - 2010
The study presented here focuses on visual preferences expressed by respondents for five relatively natural habitat types used in land reclamation projects in the North-West Bohemian brown coal basins (Czech Republic). Respondents evaluated the perceived beauty of the habitat types using a photograph questionnaire, on the basis of the positively ...
King K W - - 2010
Managed turf sites (golf courses) are the most intensively managed landscapes in the urban environment. Yet, long-term watershed scale studies documenting the environmental transport of agrichemicals applied to these systems are rare. The objective of this study was to quantify the surface discharge losses of two commonly applied pesticides (chlorothalonil ...
Pyc Mary A - - 2010
Two recent studies have led to discrepant findings regarding students' decisions to mass or space practice of to-be-learned items: Son (2004) reported that participants chose to mass practice of difficult items more than that of easy items, whereas Benjamin and Bird (2006) reported the opposite. To resolve this apparent discrepancy, ...
Dorn S D - - 2010
Irritable bowel syndrome is an extremely common and costly condition. Because there is no cure, patients must be supported to manage their own condition. To assess systematically the interventions used to support irritable bowel syndrome patient self-management. A search of PubMed, EMBASE, CINAHL and PsycINFO was performed to identify all ...
Belcastro Maria Giovanna - - 2010
The Iberomaurusian necropolis of Taforalt (Morocco, 11-12000 BP), excavated by Roche in the 1950s, contains 28 multiple graves. The funerary practices of the Taforalt population have been the focus of a previous work (Mariotti et al., 2009). In the absence of the excavation records of the necropolis, these funerary practices ...
Subramanian B - - 2010
Congenital fusion of the jaws is the inability to open the mouth at the time of birth. It occurs as a result of fusion of the jaws or fusion of the mandible to zygoma or temporal bone. The authors report four case studies and describe their management protocol.
Tamizuddin Shaista - - 2010
OBJECTIVE: To assess knowledge, attitude and practices regarding Chronic kidney disease (CKD) and referral to Nephrologists on the basis of estimated Glomerular filtration rate (eGFR) reporting with Modification of Diet in Renal Disease (MDRD). METHODS: This is a cross-sectional study. It was conducted at Shifa International Hospital, Islamabad in January ...
Li Mei-Kuen - - 2010
BACKGROUND: Constipation is a common health problem that adversely affects an individual's general health and quality of life. Constipated people usually manage the problem by taking laxatives and by modifying their lifestyle even if such have questionable therapeutic effects. Auriculotherapy, a safe treatment modality in Chinese medicine, has been reported ...
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