Recommendations concerning the intake of vitamin D and/or sunlight exposure in the handling of patients with vitamin D deficiency remain a matter of debate. The present study of the German network of dermato-oncologists (Onkoderm e.V.) refers to an inquiry conducted among general practitioners on this and related issues. Based on ...

Making correct diagnoses is the foundation of clinical practice in traditional Chinese medicine (TCM). The diversity in making diagnoses is one of the leading handicaps for the proper use of TCM. This study explores the key components for the diagnosis of qi deficiency among TCM experts. A modified Delphi process ...

Laboratory medicine practice guidelines (LMPGs) are an important part of clinical laboratory medicine. The Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument has been developed to evaluate the process of practice-guideline development and the quality of reporting. We assessed the applicability of AGREE II in assessing the ...

INTRODUCTION: Little is known of practice patterns on advanced prostate cancer (PC) in Spain. The study objectives were to investigate practice patterns in the management of PC and to determine the adherence to the 2007 Spanish guidelines for the management of PC. MATERIALS AND METHODS: An epidemiological, cross-sectional study was ...

OBJECTIVE: The objective of this study was to assess the quality of clinical practice guidelines providing diagnostic recommendations on pheochromocytoma (PHEO) using the new Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument and to promote the development of clinical guidelines. RESEARCH DESIGN AND METHODS: We searched MEDLINE and ...

The design of lead and drug-like molecules with expected desired properties and feasible chemical synthesis is one of the main objectives of computational and medicinal chemists. Prediction of synthetic feasibility of de novo molecules is often achieved by the use of in-silico tools or by advices received from medicinal and ...

To examine the Eastern-Western difference in the interpretation of Integrative Medicine Attitude Questionnaire (IMAQ) by assessing the psychometric properties of a revised Chinese medicine (CM)-specific version of IMAQ (CM-IMAQ). Factor and Rasch analysis were performed with data collected from a mail survey of 165 Hong Kong Western medical doctors (WMD) ...

PURPOSE: To describe how and why internal medicine clerkship directors (CDs) use locally developed, faculty-written (LFW) examinations. METHOD: In 2009, the Clerkship Directors in Internal Medicine conducted an annual, online, confidential survey of its 107 U.S. and Canadian institutional members, including questions about LFW examinations. Data were analyzed using descriptive ...

Tibetan medicine offers an ancient, timely model for the promotion of health and treatment of disease by teaching individuals to make healthy lifestyle choices. This holistic model consists of analyzing one's unique constitution and recommending supportive lifestyle modifications. An experienced Tibetan medicine practitioner is the gold standard for constitutional assessment. ...

Manager attitude is influential in female employees' perceptions of workplace breastfeeding support. Currently, no instrument is available to assess manager attitude toward supporting women who wish to combine breastfeeding with work. We developed and piloted an instrument to measure manager attitudes toward workplace breastfeeding support entitled the "Managers' Attitude Toward ...

Frequently occurring symptoms with opposite poles like 'Cold ameliorates/aggravates' are regarded valuable for homeopathic practice, but are insufficiently assessed and impossible to handle with conventional repertorisation. In a pilot study 30 questions out of a standard questionnaire in 102 cases responding well to five medicines were analysed and compared with ...

A substantial need exists for developing and validating a range of biomarkers that would address a number of important unmet clinical needs in the MS field. In spite of considerable efforts over last years, very few putative biomarkers have been fully validated or successfully integrated into routine clinical practice. Here, ...

Citation information: Theodossiades J, Myint J, Murdoch IE, Edgar DF & Lawrenson JG. Does optometrists' self-reported practice in glaucoma detection predict actual practice as determined by standardised patients? Ophthalmic Physiol Opt 2012. doi: 10.1111/j.1475-1313.2012.00898.x ABSTRACT: Purpose:  Questionnaires are commonly used as a proxy measure of clinical practice; however their application ...

Chemical absorption with aqueous amine solvents is the most advanced technology for post-combustion capture (PCC) of CO2 from coal-fired power stations and a number of pilot scale programs are evaluating novel solvents, optimising energy efficiency and validating engineering models. However, the development of commercial scale PCC also requires effective solvent ...

The 2011 annual conference of the American Association of Pharmaceutical Scientists, held in Washington DC, USA, hosted a roundtable entitled: 'Update of the US FDA/European Medicines Agency (EMA) harmonization of their bioanalytical guidance - Global Bioanalytical Consortium activity and impact on small and large molecules.' The roundtable was initiated with ...

This article discusses specific issues related to the market access of biosimilars. Biopharmaceuticals are complex molecules produced by living cells. Copies of these medicines, called biosimilars, are not identical to their reference medicine and therefore specific regulatory requirements apply. When considering the use of biosimilars, the question of the degree ...

Medicine vendors fill the gap created by inadequate skilled professionals required for medicine procurement, storage, and distribution in developing countries. To evaluate self-medication practice and medicine knowledge among medicine vendors and to determine if a relationship exists between both. A descriptive, cross-sectional study was conducted, using a pretested questionnaire on ...

Applications of regenerative medicine technology may offer novel therapies for patients with injuries, end-stage organ failure, or other clinical problems. Currently, patients suffering from diseased and injured organs can be treated with transplanted organs. However, there is a severe shortage of donor organs that is worsening yearly as the population ...

Nanomedicine is an interdisciplinary research field where chemistry, physics, biology, engineering, nanotechnology, and medicine meet one other. Many novel nanoparticles have been designed, synthesized, and evaluated for selective targeting of cancer cells, delivering, and releasing the anticancer drugs in a controlled manner. In this review article we discuss the current ...

Three- and four-digit International Classification of Diseases (ICD-10) is not a reliable classification system in primary care. The reliability of the International Classification of Primary Care (ICPC-2) as an alternative coding system has not yet been investigated in a German general practice setting. Cross-sectional data were collected during a one ...

The Mapuche communities living in the urban areas of Chile have undergone radical cultural changes due to Christian conversion. This article analyzes the influence of these changes on the Mapuche ideas and practices of the traditional healers (machi) and patients in Temuco (IX Region), Chile, and the changes and adaptations ...

The present study aims to reflect on, and analyse, one particular approach to the award of a Professional Doctorate. The concept of the 'Professional' Doctorate offers opportunities for the development of work-based skills which transcend professional boundaries. There is now an established basis for Professional Doctorates with many Universities offering ...

Orangutan survival is threatened by habitat loss and illegal killing. Most wild populations will disappear over the next few decades unless threats are abated. Saving orangutans is ultimately in the hands of the governments and people of Indonesia and Malaysia, which need to ensure that habitats of viable orangutan populations ...

The forensic pathologist has always had a central role in the identification of the dead in every day practice, in accidents, and in disasters involving hundreds or thousands of victims. This role has changed in recent years, as advances in forensic odontology, genetics and anthropology have improved the chances of ...

The use of stem cells is galvanizing regenerative medicine research. An analysis of recent trends as typified by articles published between 2009 and 2010 in the journals Cell Transplantation - The Regenerative Medicine Journal and Medical Science Monitor demonstrate the increasing importance of stem cell research as being on the ...

To assess the quality of the first batch of Chinese evidence-based clinical practice guidelines (CPGs) in Traditional Chinese Medicine (TCM) using the Appraisal of Guidelines for Research and Evaluation (AGREE) instrument. Evidence-based CPGs in TCM supported by the World Health Organization Western Pacific Regional Office (WHO/WPRO) and whose development was ...

Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of an unsaturated δ-keto ester derivative with (R)-phenylglycinol and the stereoselective hydrogenation of the resulting tricyclic oxazoloquinolone lactams.

Objectives  The study evaluated the compliance of community pharmacies with legal requirements as laid down by the drug regulatory framework in Pakistan. Methods  An exploratory cross sectional survey was conducted with a total of 371 randomly selected community pharmacies in three cities in Pakistan, namely Islamabad (n = 118), Peshawar (n = 120) and ...

The process of image review and interpretation has become increasingly complex and challenging for today's nuclear medicine physician from many perspectives, especially with regard to workstation integration and reading room ergonomics. With the recent proliferation of hybrid imaging systems, this complexity has increased rapidly, along with the number of studies ...

Interview with Jonathan Thomas We talked to Jonathan Thomas, newly elected Chairman of the California Institute for Regenerative Medicine (CIRM), a few weeks into a role he describes as "the opportunity of the lifetime" to find out what he sees as the key goals for the CIRM and why patient ...

The National Blood Foundation (NBF) support was critical in the author's research career development. The NBF support came in the form of a start-up seed grant that she got from the American Association of Blood Banks, an organization that advances the practice and standards of transfusion medicine and cellular therapies ...

The range of medicines and technologies that are essential for sexual and reproductive health care is well established, but access to them is far from universally assured, particularly in less developed countries. This paper shows how the pharmaceutical industry plays a major role in the lack of access to essential ...

In the context of a competitive knowledge-based economy, the knowledge provided by a firm's founders is one of the most important measures of success. This paper aims to identify the role of national culture on a founder's knowledge practices in a modern organisation. Using data collected from 258 Small to ...

Performance appraisal (PA) is a key human resource activity in organizations. However, in this global economy, we know little about how societal cultures affect PA practices. In this study, we address this gap by focusing on 2 complementary issues: (a) the influence of societal (national) cultural practices on PA practices ...

PARLOUR R and MCCORMACK B. Nursing Inquiry 2011 Blending critical realist and emancipatory practice development methodologies: making critical realism work in nursing research This paper examines the efficacy of facilitation as a practice development intervention in changing practice within an Older Person setting and in implementing evidence into practice. It ...

Abstract Background aims. Regulatory requirements for the manufacturing of cell products for clinical investigation require a significant level of record-keeping, starting early in process development and continuing through to the execution and requisite follow-up of patients on clinical trials. Central to record-keeping is the management of documentation related to patients, ...

Challenges to engage pharmacy customers in medicine dialogues at the counter have been identified comprising a new and extended clinical role for pharmacists in the health care system. This article seeks to expand understanding of factors involved in successful interaction at the pharmacy counter between customers and pharmacy staff to ...

What's known on the subject? and What does the study add? Urology was one of the first specialties to report the introduction of regenerative medicine into clinical practice and has been at the forefront of scientific innovation. Despite the scale of investment and research effort, the promise of regenerative medicine ...

This tutorial review highlights the way in which the Baylis-Hillman reaction has been increasingly attracting the attention of synthetic and medicinal chemists; it not only helps in originating new ideas to create novel methodologies and molecules but also offers intellectual challenges to understand and address the present day needs in ...

The aim of this study was to pay tribute to the memory of extraordinary Croatian Professor of children's and preventive dentistry Sime Kordić on the occasion of the 100th anniversary of his birth. The biography and work of this scientist and teacher were presented, as well as his researches about ...

currie k. & grundy m. (2011) Journal of Nursing Management19, 933-942 Building foundations for the future: the NHS Scotland advanced practice succession planning development pathway Aim  To highlight implications for managers from the implementation of a national advanced practice succession planning development pathway within Scotland. Background  Internationally, advanced practice posts ...

Where does dentistry fit into the field of regenerative medicine? Based on the fact that the goal of regenerative medicine is to restore function to damaged organs and tissues, it is apparent that dentistry, which has long embraced the concept of restoring function of damaged teeth, has embraced this goal ...

Shrines associated with the deity Tongnaab in the Talensi region of northern Ghana formed the centre of a precolonial regional cult that encompassed a variety of peoples in the savannas of the Volta basin. Despite attempts by the British colonial state to destroy the shrines and to suppress ritual activity ...

The history of biomaterials research is seriously surveyed. It is found that an immutable way of thinking for developing biomaterials is rooted deeply in Western medicine and biology. It is necessary to modify or change the current status of thinking. In this paper, the author presents an idea to research ...

The mineral, organic and elemental composition of medicine clays from three shrines in the Tong Hills in northern Ghana (Gbankil, Kusanaab, and Yaane) are assessed to ascertain what additives they might contain and the implications for their recognition, for example in archaeological contexts. These are clays that are widely used ...

Abstract Objectives: The use of complementary and alternative medicine (CAM) has increased in Western countries, with women identified as the primary users. Women's use of CAM in reproductive health is well documented; however, little is known about the use of CAM to enhance fertility, despite anecdotal evidence that this is ...

In Argentina, there are numerous native species which are an important source of natural products and which are traditionally used in medicinal applications. Some of these species are going through an intense extraction process in their natural habitat which may affect their genetic diversity. The aim of this study was ...

On March 9th, 2011, the eminent scholar of Iranian studies, historian, bibliographer, Persian manuscript expert, journalist, biographer and writer, Iraj Afshar passed away at the age of 85 in Tehran. His demise was a great loss to Iranian culture. He edited or wrote around 300 books in various fields of ...

OBJECTIVE: To identify publishers of pharmacotherapeutic information not found in biomedical journals that focuses on evaluating and providing advice on medicines and to develop a search engine to access this information. METHODS: Compiling web sites that publish information on the rational use of medicines and have no commercial interests. Free-access ...

This essay considers the implications of a shift in focus from ideas to practices in the history of alchemy. On the one hand, it is argued, this new attention to practice highlights the diversity of ways that early modern Europeans engaged alchemy, ranging from the literary to the entrepreneurial and ...