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Kaminski Mitchell V MV Jr Mitchell V. Kaminski Jr, MD, FACS, FACN, Fellow, American Colleges of Surgeons and Nutrition, and President/Medical Director, Holistic Wound Healing Service, Niles, Illinois. James J. Drinane, Bsci., Research Associate and Medical Student, Des Moines University, Des Moines, - - 2014
Wound healing is a complex process that is influenced by multiple systemic factors, including nutritional status. While nutritional support is commonly recognized as an important aspect of comprehensive wound management, the focus is typically on replacement of macronutrients, specifically calories and protein. Our experience strongly suggests that micronutrients are equally ...
Singh Rani H RH Division of Medical Genetics, Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, - - 2014
The effectiveness of a phenylalanine-restricted diet to improve the outcome of individuals with phenylalanine hydroxylase deficiency (OMIM no. 261600) has been recognized since the first patients were treated 60 years ago. However, the treatment regime is complex, costly, and often difficult to maintain for the long term. Improvements and refinements ...
Blombery Piers P Department of Haematology, University College London Hospital, London, - - 2014
Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening thrombotic microangiopathy which causes significant morbidity and mortality unless promptly recognized and treated. The underlying pathogenesis of TTP is a severe deficiency in ADAMTS13 activity, a metalloprotease that cleaves ultralarge von Willebrand factor multimers. This deficiency is either autoantibody mediated (acquired TTP) ...
Buroni Federica E - - 2013
The aim of the study was to identify deficiencies in product labelling instructions for reconstitution and in the quality control directions detailed in the technical leaflets (TLs) or summary product characteristic (SPC) sheets of commonly used technetium labelling cold kits. The reconstitution and quality control directions in 25 TLs/SPCs were ...
Carter Sherry L - - 2013
Approximately 70% of the world's population is lactase deficient. This article reviews the evolutionary history of lactase deficiency, recent recommendations to establish screening, and clinical practice guidelines for increased diagnosis of this important, yet often misunderstood condition of malabsorption.
Seshia Shashi S - - 2013
The evidence-based medicine (EBM) paradigm, introduced in 1992, has had a major and positive impact on all aspects of health care. However, widespread use has also uncovered some limitations; these are discussed from the perspectives of two clinicians in this, the first of a two part narrative review. For example, ...
Fadoo Zehra - - 2013
Congenital Factor XIII (FXIII) deficiency is a rare, inherited, autosomal recessive coagulation disorder. Most mutations of this condition are found in the A-subunit with almost half these being missense mutations. Globally, approximately one in three million people suffer from this deficiency. Factor XIII deficiency is associated with severe life threatening ...
Feng Yan - - 2013
Objective. Initial optimized prescription of Chinese herb medicine for unstable angina (UA). Methods. Based on partially observable Markov decision process model (POMDP), we choose hospitalized patients of 3 syndrome elements, such as qi deficiency, blood stasis, and turbid phlegm for the data mining, analysis, and objective evaluation of the diagnosis ...
Almuzaini Tariq T Academic Division of Child Health, University of Nottingham, Derbyshire Children's Hospital, Derby, - - 2013
To determine the extent of substandard and falsified medicines in the UK. A retrospective review of drug alerts and company-led recalls. The Medicines and Healthcare Products Regulatory Agency (MHRA) website search for drug alerts issued between 2001 and 2011. Drug alerts related to quality defect in medicinal products. Relevant data ...
Reinhold Uwe - - 2012
Recommendations concerning the intake of vitamin D and/or sunlight exposure in the handling of patients with vitamin D deficiency remain a matter of debate. The present study of the German network of dermato-oncologists (Onkoderm e.V.) refers to an inquiry conducted among general practitioners on this and related issues. Based on ...
Chiang Hui-Chu - - 2012
Making correct diagnoses is the foundation of clinical practice in traditional Chinese medicine (TCM). The diversity in making diagnoses is one of the leading handicaps for the proper use of TCM. This study explores the key components for the diagnosis of qi deficiency among TCM experts. A modified Delphi process ...
Don-Wauchope Andrew C - - 2012
Laboratory medicine practice guidelines (LMPGs) are an important part of clinical laboratory medicine. The Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument has been developed to evaluate the process of practice-guideline development and the quality of reporting. We assessed the applicability of AGREE II in assessing the ...
Zapatero Almudena - - 2012
INTRODUCTION: Little is known of practice patterns on advanced prostate cancer (PC) in Spain. The study objectives were to investigate practice patterns in the management of PC and to determine the adherence to the 2007 Spanish guidelines for the management of PC. MATERIALS AND METHODS: An epidemiological, cross-sectional study was ...
Yan Juping - - 2012
OBJECTIVE: The objective of this study was to assess the quality of clinical practice guidelines providing diagnostic recommendations on pheochromocytoma (PHEO) using the new Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument and to promote the development of clinical guidelines. RESEARCH DESIGN AND METHODS: We searched MEDLINE and ...
Bonnet Pascal - - 2012
The design of lead and drug-like molecules with expected desired properties and feasible chemical synthesis is one of the main objectives of computational and medicinal chemists. Prediction of synthetic feasibility of de novo molecules is often achieved by the use of in-silico tools or by advices received from medicinal and ...
Chung Vincent C H - - 2012
To examine the Eastern-Western difference in the interpretation of Integrative Medicine Attitude Questionnaire (IMAQ) by assessing the psychometric properties of a revised Chinese medicine (CM)-specific version of IMAQ (CM-IMAQ). Factor and Rasch analysis were performed with data collected from a mail survey of 165 Hong Kong Western medical doctors (WMD) ...
Kelly William F - - 2012
PURPOSE: To describe how and why internal medicine clerkship directors (CDs) use locally developed, faculty-written (LFW) examinations. METHOD: In 2009, the Clerkship Directors in Internal Medicine conducted an annual, online, confidential survey of its 107 U.S. and Canadian institutional members, including questions about LFW examinations. Data were analyzed using descriptive ...
Cameron Miriam E - - 2012
Tibetan medicine offers an ancient, timely model for the promotion of health and treatment of disease by teaching individuals to make healthy lifestyle choices. This holistic model consists of analyzing one's unique constitution and recommending supportive lifestyle modifications. An experienced Tibetan medicine practitioner is the gold standard for constitutional assessment. ...
Chow Tan - - 2012
Manager attitude is influential in female employees' perceptions of workplace breastfeeding support. Currently, no instrument is available to assess manager attitude toward supporting women who wish to combine breastfeeding with work. We developed and piloted an instrument to measure manager attitudes toward workplace breastfeeding support entitled the "Managers' Attitude Toward ...
Rutten Lex Alb - - 2012
Frequently occurring symptoms with opposite poles like 'Cold ameliorates/aggravates' are regarded valuable for homeopathic practice, but are insufficiently assessed and impossible to handle with conventional repertorisation. In a pilot study 30 questions out of a standard questionnaire in 102 cases responding well to five medicines were analysed and compared with ...
Rajasekharan Sathyanath - - 2012
A substantial need exists for developing and validating a range of biomarkers that would address a number of important unmet clinical needs in the MS field. In spite of considerable efforts over last years, very few putative biomarkers have been fully validated or successfully integrated into routine clinical practice. Here, ...
Theodossiades Julia - - 2012
Citation information: Theodossiades J, Myint J, Murdoch IE, Edgar DF & Lawrenson JG. Does optometrists' self-reported practice in glaucoma detection predict actual practice as determined by standardised patients? Ophthalmic Physiol Opt 2012. doi: 10.1111/j.1475-1313.2012.00898.x ABSTRACT: Purpose:  Questionnaires are commonly used as a proxy measure of clinical practice; however their application ...
Reynolds Alicia J - - 2012
Chemical absorption with aqueous amine solvents is the most advanced technology for post-combustion capture (PCC) of CO2 from coal-fired power stations and a number of pilot scale programs are evaluating novel solvents, optimising energy efficiency and validating engineering models. However, the development of commercial scale PCC also requires effective solvent ...
Garofolo Fabio - - 2012
The 2011 annual conference of the American Association of Pharmaceutical Scientists, held in Washington DC, USA, hosted a roundtable entitled: 'Update of the US FDA/European Medicines Agency (EMA) harmonization of their bioanalytical guidance - Global Bioanalytical Consortium activity and impact on small and large molecules.' The roundtable was initiated with ...
Simoens Steven - - 2012
This article discusses specific issues related to the market access of biosimilars. Biopharmaceuticals are complex molecules produced by living cells. Copies of these medicines, called biosimilars, are not identical to their reference medicine and therefore specific regulatory requirements apply. When considering the use of biosimilars, the question of the degree ...
Atala Anthony - - 2012
Applications of regenerative medicine technology may offer novel therapies for patients with injuries, end-stage organ failure, or other clinical problems. Currently, patients suffering from diseased and injured organs can be treated with transplanted organs. However, there is a severe shortage of donor organs that is worsening yearly as the population ...
Majumdar Debatosh - - 2012
Nanomedicine is an interdisciplinary research field where chemistry, physics, biology, engineering, nanotechnology, and medicine meet one other. Many novel nanoparticles have been designed, synthesized, and evaluated for selective targeting of cancer cells, delivering, and releasing the anticancer drugs in a controlled manner. In this review article we discuss the current ...
Frese T - - 2012
Three- and four-digit International Classification of Diseases (ICD-10) is not a reliable classification system in primary care. The reliability of the International Classification of Primary Care (ICPC-2) as an alternative coding system has not yet been investigated in a German general practice setting. Cross-sectional data were collected during a one ...
Auta Asa - - 2012
Medicine vendors fill the gap created by inadequate skilled professionals required for medicine procurement, storage, and distribution in developing countries. To evaluate self-medication practice and medicine knowledge among medicine vendors and to determine if a relationship exists between both. A descriptive, cross-sectional study was conducted, using a pretested questionnaire on ...
Farkas Henriette H 3rd Department of Internal Medicine, Semmelweis University, Kutvolgyi ut 4, H-1225 Budapest, - - 2012
Hereditary angioedema resulting from the deficiency of the C1 inhibitor (HAE-C1-INH) is a rare, but potentially life-threatening disorder characterized by paroxysmal episodes of subcutaneous or submucosal edema. Early diagnosis is essential. Management is aimed at the prompt elimination of full-fledged attacks, as well as at the prevention of edematous episodes. ...
Torri Maria Costanza - - 2011
The Mapuche communities living in the urban areas of Chile have undergone radical cultural changes due to Christian conversion. This article analyzes the influence of these changes on the Mapuche ideas and practices of the traditional healers (machi) and patients in Temuco (IX Region), Chile, and the changes and adaptations ...
Fulton John - - 2012
The present study aims to reflect on, and analyse, one particular approach to the award of a Professional Doctorate. The concept of the 'Professional' Doctorate offers opportunities for the development of work-based skills which transcend professional boundaries. There is now an established basis for Professional Doctorates with many Universities offering ...
Meijaard Erik - - 2011
Orangutan survival is threatened by habitat loss and illegal killing. Most wild populations will disappear over the next few decades unless threats are abated. Saving orangutans is ultimately in the hands of the governments and people of Indonesia and Malaysia, which need to ensure that habitats of viable orangutan populations ...
Schuliar Yves - - 2011
The forensic pathologist has always had a central role in the identification of the dead in every day practice, in accidents, and in disasters involving hundreds or thousands of victims. This role has changed in recent years, as advances in forensic odontology, genetics and anthropology have improved the chances of ...
Eve David J - - 2011
The use of stem cells is galvanizing regenerative medicine research. An analysis of recent trends as typified by articles published between 2009 and 2010 in the journals Cell Transplantation - The Regenerative Medicine Journal and Medical Science Monitor demonstrate the increasing importance of stem cell research as being on the ...
Yu Wen-Ya - - 2011
To assess the quality of the first batch of Chinese evidence-based clinical practice guidelines (CPGs) in Traditional Chinese Medicine (TCM) using the Appraisal of Guidelines for Research and Evaluation (AGREE) instrument. Evidence-based CPGs in TCM supported by the World Health Organization Western Pacific Regional Office (WHO/WPRO) and whose development was ...
Amat Mercedes - - 2011
Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of an unsaturated δ-keto ester derivative with (R)-phenylglycinol and the stereoselective hydrogenation of the resulting tricyclic oxazoloquinolone lactams.
Hussain Azhar - - 2012
Objectives  The study evaluated the compliance of community pharmacies with legal requirements as laid down by the drug regulatory framework in Pakistan. Methods  An exploratory cross sectional survey was conducted with a total of 371 randomly selected community pharmacies in three cities in Pakistan, namely Islamabad (n = 118), Peshawar (n = 120) and ...
Zemariame Nigist - - 2011
The process of image review and interpretation has become increasingly complex and challenging for today's nuclear medicine physician from many perspectives, especially with regard to workstation integration and reading room ergonomics. With the recent proliferation of hybrid imaging systems, this complexity has increased rapidly, along with the number of studies ...
Thomas Jonathan - - 2011
Interview with Jonathan Thomas We talked to Jonathan Thomas, newly elected Chairman of the California Institute for Regenerative Medicine (CIRM), a few weeks into a role he describes as "the opportunity of the lifetime" to find out what he sees as the key goals for the CIRM and why patient ...
Cottingham Jane - - 2011
The range of medicines and technologies that are essential for sexual and reproductive health care is well established, but access to them is far from universally assured, particularly in less developed countries. This paper shows how the pharmaceutical industry plays a major role in the lack of access to essential ...
Cegarra-Navarro Juan Gabriel - - 2011
In the context of a competitive knowledge-based economy, the knowledge provided by a firm's founders is one of the most important measures of success. This paper aims to identify the role of national culture on a founder's knowledge practices in a modern organisation. Using data collected from 258 Small to ...
Chai Li - - 2011
The National Blood Foundation (NBF) support was critical in the author's research career development. The NBF support came in the form of a start-up seed grant that she got from the American Association of Blood Banks, an organization that advances the practice and standards of transfusion medicine and cellular therapies ...
Peretz Hilla - - 2011
Performance appraisal (PA) is a key human resource activity in organizations. However, in this global economy, we know little about how societal cultures affect PA practices. In this study, we address this gap by focusing on 2 complementary issues: (a) the influence of societal (national) cultural practices on PA practices ...
Parlour Randal - - 2011
PARLOUR R and MCCORMACK B. Nursing Inquiry 2011 Blending critical realist and emancipatory practice development methodologies: making critical realism work in nursing research This paper examines the efficacy of facilitation as a practice development intervention in changing practice within an Older Person setting and in implementing evidence into practice. It ...
Russom Diana - - 2011
Abstract Background aims. Regulatory requirements for the manufacturing of cell products for clinical investigation require a significant level of record-keeping, starting early in process development and continuing through to the execution and requisite follow-up of patients on clinical trials. Central to record-keeping is the management of documentation related to patients, ...
Kaae Susanne - - 2011
Challenges to engage pharmacy customers in medicine dialogues at the counter have been identified comprising a new and extended clinical role for pharmacists in the health care system. This article seeks to expand understanding of factors involved in successful interaction at the pharmacy counter between customers and pharmacy staff to ...
Wezel Felix - - 2011
What's known on the subject? and What does the study add? Urology was one of the first specialties to report the introduction of regenerative medicine into clinical practice and has been at the forefront of scientific innovation. Despite the scale of investment and research effort, the promise of regenerative medicine ...
Basavaiah Deevi - - 2011
This tutorial review highlights the way in which the Baylis-Hillman reaction has been increasingly attracting the attention of synthetic and medicinal chemists; it not only helps in originating new ideas to create novel methodologies and molecules but also offers intellectual challenges to understand and address the present day needs in ...
Brisky Livia - - 2011
The aim of this study was to pay tribute to the memory of extraordinary Croatian Professor of children's and preventive dentistry Sime Kordić on the occasion of the 100th anniversary of his birth. The biography and work of this scientist and teacher were presented, as well as his researches about ...
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