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Wallace Michael P MP Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, - - 2014
Much of current pharmacological practice focuses on identifying the single 'best' treatment (or course of treatments) for a particular disease. Recently, however, focus has begun to shift towards a more patient-centric rather than disease-centric approach, where personal characteristics are used to identify the optimal treatment for an individual. Adaptive treatment ...
Assina Rachid R Department of Neurological Surgery, New Jersey Medical School, Rutgers University, Newark, New - - 2014
Both the history of headache and the practice of craniotomy can be traced to antiquity. From ancient times through the present day, numerous civilizations and scholars have performed craniotomy in attempts to treat headache. Today, surgical intervention for headache management is becoming increasingly more common due to improved technology and ...
Dréno B B Department of Dermato cancerology, University Hospital Hotel Dieu, Nantes, - - 2014
Actinic keratoses (AK) are common photo-induced cutaneous lesions that may progress to invasive squamous-cell carcinoma and serve as a risk marker for skin cancer. Although numerous studies present the various therapeutic options for AK, publications that can be used to pragmatically guide dermatologists in their daily practice are limited. National ...
Eustace K K St Vincent's Hospital, Department of Dermatology, Dublin 4, - - 2014
The treatment of orofacial granulomatosis (OFG) remains challenging, and spontaneous remission is rare. We report a 43 year old male who initially presented to dermatology in 2007 following referral from oral medicine, with a 15 year history of swollen and cracked lips. Examination revealed thickened, indurated and fissured lips, cobblestoning ...
Reese Erika E Fort Belvoir Community Hospital, 9300 Dewitt Loop, Fort Belvoir, - - 2014
Marine envenomations are an important part of sports medicine. Marine sport is practiced widely, and many aquatic envenomations require quick recognition and timely action to ensure the safety and recovery of victims. Even a basic knowledge of treatments of various envenomations could help clinicians be more effective in acute treatment. ...
Wright Lakiea S LS Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA, - - 2014
In the modern era, the prevalence of asthma and allergies are increasing. It has been speculated that environmental exposures are contributing to this rise. Several studies demonstrate that common indoor allergen exposures exacerbate asthma. Minimizing exposure to allergens and remediating the environment play a critical role in the treatment of ...
Blum Johannes - - 2014
Treatment of cutaneous leishmaniasis (CL) and mucosal leishmaniasis (ML) in travelers is still controversial. Over the last decade, national and international consortia have published recommendations for treating CL in travelers. These guidelines harmonize many issues, but there are some discrepancies. Leishmania parasites causing CL can now be genotyped by polymerase ...
Spasovski Goce G State University Hospital Skopje, Skopje, - - 2014
Hyponatraemia, defined as a serum sodium concentration <135 mmol/l, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. It can lead to a wide spectrum of clinical symptoms, from subtle to severe or even life threatening, and is associated with increased mortality, morbidity and ...
Nimrouzi Majid M Research Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, - - 2014
Traditional Persian medicine is based on humoral medical concepts. In the case of abundant blood in the body, tabi'at (body nature) deals with this imbalance by elimination of the morbid substances via some controlling mechanisms. If tabi'at could not react properly, the physician should prescribe an intervention to let the ...
Spasovski Goce G State University Hospital Skopje, Skopje, - - 2014
Hyponatraemia, defined as a serum sodium concentration <135 mmol/L, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. Hyponatraemia is present in 15-20 % of emergency admissions to hospital and occurs in up to 20 % of critically ill patients. Symptomatology may vary from subtle to severe ...
- - 2014
The Kidney Disease: Improving Global Outcomes (KDIGO) organization developed clinical practice guidelines on lipid management for all adults and children with chronic kidney disease (CKD). Thirteen recommendations were obtained from the available evidence outlining a three-step management including assessment in all, treatment in many, and follow-up measurements in few. A ...
Kabir Mohammad Humayun - - 2014
The number of tribes present within Bangladesh has been estimated to approximate one hundred and fifty. Information on traditional medicinal practices, particularly of the smaller tribes and their clans is lacking. It was the objective of the study to document the tribal medicinal practices of the Deb barma clan of ...
Balhara Kamna S - - 2014
This article describes the epidemiology and presentation of human envenomation from marine organisms. Venom pathophysiology, envenomation presentation, and treatment options are discussed for sea snake, stingray, spiny fish, jellyfish, octopus, cone snail, sea urchin, and sponge envenomation. The authors describe the management of common exposures that cause morbidity as well ...
Fanfair Robyn Neblett RN Division of STD Prevention, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, US Centers for Disease Control and Prevention, Atlanta, - - 2014
Sexually transmitted diseases (STDs) and their associated syndromes are extremely common in clinical practice. Early diagnosis, appropriate treatment, and partner management are important to ensure sexual, physical, and reproductive health in our patients.
Wells R A RA Sunnybrook Health Sciences Centre, Toronto, - - 2014
Myelodysplastic syndromes (mdss) constitute a heterogeneous group of malignant hematologic disorders characterized by marrow dysplasia, ineffective hematopoiesis, peripheral blood cytopenias, and pronounced risk of progression to acute myeloid leukemia. Azacitidine has emerged as an important treatment option and is recommended by the Canadian Consortium on Evidence-Based Care in mds as ...
Diamond George A GA Division of Cardiology, Cedars-Sinai Medical Center, and the Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, - - 2014
Although randomized trials and observational studies are used as the evidentiary basis of clinical practice guidelines, they are not always in agreement. Limitations in the process of randomization in the former and the selective referral of patients for treatment as a consequence of clinical "risk stratification" in the latter are ...
Karsdal Morten A MA Nordic Bioscience, Herlev Hovedgade, DK-2730, Herlev, - - 2014
Ethical, clinical and economic considerations highlight the pressing need to advance the identification of optimal treatments for each individual patient. PHC may provide significant benefit in the treatment of a number of clinical indications, characterised by costly therapy, low response rates and significant problems associated with trial and error prescription, ...
McAlindon T E TE Division of Rheumatology, Tufts Medical Center, Boston, MA, USA. Electronic address: - - 2014
To develop concise, up-to-date, patient-focused, evidence-based, expert consensus guidelines for the management of knee osteoarthritis, intended to inform patients, physicians, and allied health care professionals worldwide. Thirteen experts from relevant medical disciplines (primary care, rheumatology, orthopedics, physical therapy, physical medicine and rehabilitation, and evidence-based medicine), three continents and ten countries ...
Ramsberger Gail G Department of Speech, Language, and Hearing - - 2014
Given the proliferation of tablets and smartphones, there is a rising desire to use these technologies and apps in clinical practice. This article offers best-practice guidelines for integrating apps into aphasia rehabilitation. In concert with evidence-based practice guidelines, it describes the steps for deciding which apps to consider and how ...
Jang Su Hee - - 2014
During their reproductive years about 10% of women experience some kind of symptoms before menstruation (PMS) in a degree that affects their quality of life (QOL). Acupuncture and herbal medicine has been a recent favorable therapeutic approach. Thus we aimed to review the effects of acupuncture and herbal medicine in ...
Daniel Gregory B - - 2014
Thyroid scintigraphy is performed in cats and dogs and has been used to a limited degree in other species such as the horse. Thyroid scintigraphy is most commonly used to aid in the diagnosis and treatment management of feline hyperthyroidism but is also used in the evaluation of canine hypothyroidism ...
Mori Amani Thomas AT Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway ; School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, - - 2014
Insufficient access to essential medicines is a major health challenge in developing countries. Despite the importance of Standard Treatment Guidelines and National Essential Medicine Lists in facilitating access to medicines, little is known about how they are updated. This study aims to describe the process of updating the Standard Treatment ...
Blanco Fernando F Universidad de Deusto, Departamento de Fundamentos y Métodos de la Psicología, Bilbao, - - 2014
Some alternative medicines enjoy widespread use, and in certain situations are preferred over conventional, validated treatments in spite of the fact that they fail to prove effective when tested scientifically. We propose that the causal illusion, a basic cognitive bias, underlies the belief in the effectiveness of bogus treatments. Therefore, ...
Spasovski Goce G State University Hospital Skopje, Skopje, - - 2014
Hyponatraemia, defined as a serum sodium concentration <135 mmol/l, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. It can lead to a wide spectrum of clinical symptoms, from subtle to severe or even life threatening, and is associated with increased mortality, morbidity and length ...
Liu Ping P Key Laboratory of Traditional Chinese Medicine Resource and Compound Prescription of the Ministry of Education, Hubei University of Chinese Medicine, Wuhan 430065, - - 2014
Traditional Chinese medicine (TCM) is practiced in the Chinese health care system for more than 2,000 years. In recent years, herbal medicines, which are used to treat Alzheimer's disease (AD) in China based on TCM or modern pharmacological theories have attracted considerable attention. In this paper, we discuss etiology and ...
Homisak Lynn - - 2014
Successful practices do not follow others, but rather make their own paths and follow their own agendas. When doctors hear about a new treatment or technology, there are those who are early adopters and will embrace anything new and exciting, while others are followers and wait until all the bugs ...
Blay Jean-Yves JY 1Department of Medecine, Centre Léon Bérard 2Unité INSERM 1052, CRCL Eq 11 Centre Léon Bérard 3Université Claude Bernard Lyon 1, Lyon, - - 2013
The current refinement of nosological classification of sarcoma which integrates molecular typing with a growing number of subtypes contrasts with the one-size-fits-all approach proposed in clinical practice guidelines for both local treatment and systemic treatment in the past. However, there is a growing proportion of sarcomas in which specific treatment ...
Kamal Rama M RM Nijmegen Institute for Scientist-Practitioners in Addiction (NISPA), 6525 ED Nijmegen, The Netherlands; Novadic-Kentron Addiction Care Network, 5260 AE Vught, The Netherlands. Electronic address: - - 2013
GHB dependent patients can suffer from a severe and sometimes life-threatening withdrawal syndrome. Therefore, most of the patients are treated within inpatient settings. However, some prefers an outpatient approach to treatment. The aim of this study was to develop decision rules for addiction physicians to determine whether an outpatient or ...
Scott James S - - 2013
11b-Hydroxysteroid dehydrogenase type 1 (11b-HSD1) is the enzyme primarily responsible for the regulation of intracellular cortisol levels. Inhibition of 11b-HSD1 is an attractive mechanism for the treatment of obesity and other elements of the metabolic syndrome. Emerging literature also supports a potential role in the treatment of other unmet medical ...
Russell David F - - 2013
Osteoarthritis of the lateral tarsometatarsal joints is less common than that which is seen in the 1st-3rd tarsometatarsal joints. Despite a suspected increase in incidence of tarsometatarsal arthritis and consequently the burden of disability and economic impact, guidelines for treatment and decision making remain scarce. When conservative treatment fails, lateral ...
Bronstein Marcello D - - 2013
Evidence-based treatment guidelines have undoubtedly advanced medical practice and supported optimal management of acromegaly, but their application may be hampered by limited access to the latest treatment options. In this retrospective, narrative review, the authors revisited existing treatment guidelines for acromegaly in Latin America. These were considered in conjunction with ...
Altahan Abdulrahman M - - 2013
Abstract We have reviewed the clinical literature with reference to the local applicability of guidelines for the diagnosis and management of multiple sclerosis (MS) in the Middle East. There is a substantial burden of MS in the region: the prevalence of the disease appears to have increased markedly in recent ...
Papiris Spyros A - - 2013
Fibrotic interstitial lung diseases (ILDs) are commonly encountered in scleroderma where they significantly influence prognosis. The mainstay of treatment in idiopathic fibrotic ILDs for the past 30 years was based on the combined administration of prednisone and cyclophosphamide (CYC) or prednisone, azathioprine plus N-acetyl cysteine, recently proved ineffective and harmful. Rheumatologists ...
de Ziegler Dominique - - 2013
Risk and safety management (RSM) is receiving increasing attention in medicine, with the goals of reducing medical error and increasing quality of care. The principles and tools of RSM can and should be applied to assisted reproductive technology (ART), a field that has already made significant progress in reducing the ...
Magge Suma S - - 2013
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder, characterized by chronic or recurrent abdominal pain with constipation, diarrhea and/or an alternation of the two, and often bloating. Complementary and alternative medicine (CAM) consists of a group of medical treatments that are not commonly considered to be a part of ...
Kogure Toshiaki - - 2013
Rheumatoid arthritis (RA) is a heterogeneous disease. In rheumatology, researchers have not identified useful clinical markers to predict the effects of biological agents or of nonbiological, antirheumatic drugs before administration. Since the advent of biological agents, therapeutic strategies for RA have focused on early detection and early intensive treatment. Although ...
Jordan Karin - - 2013
Over the past decades major improvements in the management of chemotherapy induced nausea and vomiting (CINV) were obtained. With the correct use of antiemetic drugs, CINV can be prevented in almost 70%, and even up to, 80% of patients. Treatment guidelines enable physicians to integrate the latest clinical research into ...
Palencia Herrejón E - - 2013
In 2004 was published the first edition of the "Surviving sepsis campaign" guidelines for the management of severe sepsis and septic shock, opening a new era in the treatment of this syndrome. The paradox is that guidelines application have produced positive results despite including in some cases treatments proven ineffective. ...
Fancelli Claudia - - 2013
Pediculosis capitis is a worldwide health problem. One of the most important factor in effective head lice eradication is to ensure that infestation is adequately recognized and treated. Our survey investigated the knowledge and practice among primary care Italian pediatricians regarding to the prevention and treatment of head lice. The ...
Li Qianwen - - 2013
To assess the efficacy of Traditional Chinese Medicine (TCM) on constipation-predominant irritable bowel syndrome by focusing on the liver. Databases (domestic and foreign) were searched with the key words "irritable bowel syndrome'", "constipation", and "Chinese medicine"; the relevant articles were retrieved and evaluated. Cure rate, "remarkable efficacy", recurrence rate and ...
Malone Michael A - - 2013
Many patients suffering from pain and dysfunction attributable to musculoskeletal conditions will use some form of complementary and alternative medicine (CAM). Unfortunately, there is a paucity of both the quantity and quality of CAM treatments for specific musculoskeletal conditions. Many CAM treatments are used for a variety of musculoskeletal conditions, ...
Swerdlow Russell H - - 2013
Here we discuss a specific therapeutic strategy we call "bioenergetic medicine". Bioenergetic medicine refers to the manipulation of bioenergetic fluxes to positively affect health. Bioenergetic medicine approaches rely heavily on the law of mass action, and impact systems that monitor and respond to the manipulated flux. Since classically defined energy ...
Taylor Samantha - - 2013
Practical relevance: Chronic kidney disease (CKD) is common in humans as well as in cats, and is a significant human health problem. In feline medicine, despite recent research and improvements in our understanding of the condition, management remains limited by late diagnosis and an inadequate ability to prevent progression of ...
Byrd Zackary O - - 2013
EDUCATIONAL OBJECTIVES As a result of reading this article, physicians should be able to: 1. Understand the etiology, epidemiology, and importance of treatment of isolated subtalar dislocation. 2. Understand the most common management practices when treating isolated subtalar dislocation and identify variations in management that may affect prognosis. 3. Consolidate ...
Robin Xavier - - 2013
Network medicine aims at unraveling the cell signaling networks to propose personalized treatments for patients suffering from complex diseases. In this short review, we show the relevance of network medicine to cancer treatment by outlining the potential convergence points of the most recent technological and scientific developments in both drug ...
Huang Tzu-Ping - - 2013
Presentation of a case illustrating the benefits of traditional Chinese herbal granules for treatment of immune thrombocytopenic purpura in children. A 4-year-old girl presented with persistent immune thrombocytopenic purpura refractory to the first-line conventional treatment of steroids and intravenous immunoglobulin over 7 months. She was brought to the traditional Chinese ...
Becker Emily M - - 2013
Treatment manuals are currently the most common way treatments are disseminated to practicing clinicians, although little is known about the rates with which practicing therapists incorporate these manuals into their practice. In light of a widely acknowledged research-practice gap, understanding how often therapists are using manuals is important for shaping ...
Pastuszczak Maciej M Department of Dermatology, Jagiellonian University Medical College, Krakow, Poland. Head: Prof. Anna Wojas-Pelc MD, - - 2013
Syphilis continues to be an important epidemiologic problem. For a few years a steady increase in the incidence of this sexually transmitted disease has been observed. Advances in medical science obligate the doctor to use only such diagnostic and therapeutic approaches that are scientifically proven. Based on the European (IUSTI) ...
Kulkarni Anil D - - 2013
The principal objective of this paper is to demonstrate the role of taste and flavor in health from the ancient science of Ayurveda to modern medicine; specifically their mechanisms androles in space medicine and their clinical relevance in modern heath care. It also describes the brief history of the use ...
Sand Cézar R van der - - 2013
No local studies evaluating the knowledge of cardiologists on the management of atrial fibrillation (AF) and their adherence to these guidelines are available. To evaluate the knowledge of cardiologists on the guidelines and clinical practices for the treatment of AF, correlating it to the time since medical graduation. Cross-sectional study ...
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