A large proportion of drugs employed in clinical practice come from plants. The development of new medical agents is a lengthy and time-consuming process, with the identification of extracts with putative therapeutic effects, the isolation of active ingredients and pre-clinical studies to investigate their pharmacological profile. We propose a shortcut ...

OBJECTIVE: To examine the clinical problem of newly diagnosed diabetes/hyperglycemia in hospitals, and to develop a management strategy. METHODS: A review of the literature on outcomes and management of such patients. RESULTS: There are very few published papers on this subject, the majority being in patients with cardiovascular disease. However, ...

The specific aims of this study were to describe the experience of self-managing type 2 diabetes among rural dwelling African Americans, to identify facilitators and barriers to self-management, to describe the use of prescribed and alternative therapies, and to elicit recommendations for programs of diabetes care. Ten focus groups were ...

Individuals with diabetes receive more nutrition advice than other population segments yet little is known about how well they comply or differ in nutrient intake from the rest of the population. The present study determined the mean macronutrient intake, glycaemic index (GI), and glycaemic load (GL) of a cohort of ...

Bitter gourd (Momordica charantia) is a vegetable with pantropical distribution. It contains substances with antidiabetic properties such as charantin, vicine, and polypeptide-p, as well as other unspecific bioactive components such as antioxidants. Metabolic and hypoglycemic effects of bitter gourd extracts have been demonstrated in cell culture, animal, and human studies. ...

PURPOSE: To review special considerations in the management of adults 65 years of age and older with diabetes mellitus (DM) with particular attention to initiation of insulin in the management of type 2 DM (DM2), Medicare eligibility for insulin pump therapy, and intensive insulin therapy in both type 1 DM ...

OBJECTIVE: To develop a multidisciplinary team, the Diabetes Inpatient Safety Committee (DPSC), to effectively address the many barriers to achieving glycemic control in the inpatient setting. Methods: The development, implementation, and successes of the DPSC are described. RESULTS: By focusing on prevention of severe hypoglycemia, the DPSC identified and addressed ...

Dermatologic problems are common in diabetes, with approximately 30% of patients experiencing some cutaneous involvement during the course of their illness. Skin manifestations generally appear during the course of the disease in patients known to have diabetes, but they may also be the first presenting sign of diabetes or even ...

Diabetes mellitus has now assumed epidemic proportions in many countries of the world. With the present population of 19.4 million diabetics, and approximately 60 million by the year 2025, India would rank first in its share of the global burden of diabetes. Diabetes mellitus is characterized by derangement in carbohydrate, ...

Diabetes is a chronic incurable illness that adversely affects the lives of millions worldwide. This research project applies computing technology (in the form of Artificial Intelligence and 3D visualization) to provide a new mechanism to help improve the day to day management of blood sugar levels for diabetic patients.

OBJECTIVE: To determine the association among diabetes-related bullying, diabetes self-management, metabolic control, and depression in children and adolescents with type I diabetes (TID). STUDY DESIGN: Measures of diabetes-related bullying and depression were administered to 167 youth with TID at their regularly scheduled diabetes care visits. Parents were administered a clinician-rated ...

OBJECTIVE: To examine whether spontaneous causal attributions for blood glucose events were associated with blood glucose control (HbA(1c) [A1C]), self-management, and adjustment to diabetes. RESEARCH DESIGN AND METHODS: A total of 62 adults (31 female) with type 1 diabetes, recruited from a diabetes specialist clinic, with a mean age of ...

Fixed combination psychotropics, such as a combination of a tricyclic and a typical antipsychotic, were widely prescribed a generation ago. These products were plagued by a number of problems, including serious side effects, which caused them to fall out of favor. More recently, a fixed combination of the atypical antipsychotic ...

During the month of Ramadan, Muslims fast every day from dawn to sunset. In the healthy subject, this fasting does not have any harmful consequences on health. However, it can induce several complications for patients with diabetes. The aim of this review twofold: first, it seeks to give some clues ...

OBJECTIVE: To describe the glycaemic control, diabetes care and prevalence of complications in youth with type 2 diabetes from the Western Pacific Region. RESEARCH DESIGN AND METHODS: Cross-sectional, clinic-based audit of 331 patients aged < 18 years from 56 centres in Australia, China-Beijing, China-Shanghai, China-Hong Kong, Indonesia, Japan, South Korea, ...

Complementary and alternative medicine (CAM) is a growing form of self-care and is related to other healthy behaviors. This study examines the relationship between CAM use and diabetes self-management. A survey of rural older African American, Native American, and White adults with diabetes was conducted. Data were collected on diabetes ...

Diabetes is an increasingly common condition and hence, managing dying patients with diabetes as a co-morbidity will become a frequent challenge. It is uncertain whether there is net beneficence in preventing hyperglycaemia in diabetic patients during the terminal phase or whether the distress involved in administering therapy and blood glucose ...

Type 1 diabetes is a chronic disease that can lead to many serious complications if not properly managed. The patient and physician must work together to optimize glucose control involving both insulin administration and caloric intake. Exercise has numerous benefits and the type 1 diabetic should take advantage of these ...

Over the past years RNA interference (RNAi) has exploded as a new approach to manipulate gene expression in mammalian systems. More recently, RNAi has acquired interest as a potential therapeutic strategy. This review focuses on the potential therapeutic use of RNAi for metabolic diseases, the current understanding of RNAi biology, ...

Multivessel diffuse coronary arteriopathy is the hallmark of chronic diabetic patients. The ideal method of revascularising this group of patients is controversial. This review examines the various modalities available in the revascularisation of coronary artery disease in diabetic patients. Various trials have been conducted to compare the effectiveness of surgical ...

The goal of this research was to develop and evaluate measures of adolescent diabetes management self-efficacy and outcome expectations that reflect developmentally relevant, situation-specific challenges to current diabetes regimens. Self-efficacy for diabetes management, expected outcomes of adherence, adherence to the diabetes regimen, and glycemic control were assessed in 168 adolescents ...

Dermatologic events are considered the most relevant elements of the toxicity profile of epidermal growth factor receptor (EGFR) inhibitors. However, some nondermatologic adverse events can also be common. Although these toxicities are rarely severe, they may have fatal outcomes if not managed appropriately. For example, gefitinib (Iressa) and erlotinib (Tarceva) ...

The ESPEN guidelines on enteral nutrition are the first evidence-based European recommendations for enteral nutrition. They were established by European experts for a variety of disease groups. During guideline development it became evident that terms and definitions in clinical nutrition have been used inconsistently depending on medical disciplines as well ...

A collection of pus in the pleural space (empyema) is a dangerous condition that is usually a complication of pneumonia. Empyema can be associated with a delayed response of pneumonia to antibacterial treatment. It can lead to septicaemia, disseminated abscesses and prolonged hospitalisation. Reported mortality rates are typically 7-33%, but ...

Type 2 diabetes is increasing at an alarming rate in minority youth in the United States. Early diagnosis is important so that a treatment plan including diabetes self-management education, medical nutrition therapy, exercise, and behavioral modification can be developed to optimize blood glucose level. Prevention and treatment of hypertension and ...

OBJECTIVE: To determine whether women with pregestational diabetes obtained long-term benefits from an intensive diabetes management program during pregnancy. RESEARCH DESIGN AND METHODS: Women with pregestational diabetes who had attended an intensive diabetes management program in pregnancy between 1991 and 1999 were interviewed regarding diabetes self-management behaviors and current glycemic ...

Surgery induces a 'stress' state leading to post-operative hyperglycaemia. To investigate this effect on patients with Type 2 Diabetes Mellitus, we reviewed the records of 50 diabetic patients who underwent surgery without intraoperative insulin. Demographic features together with pre-operative and post-operative blood glucose readings were noted. 27.3% of patients with ...

Patients with diabetes mellitus are at higher risk for complications from surgery than their nondiabetic counterparts. Evidence-based guidance on the perioperative management of diabetic patients is still very limited. Management is best guided by careful preoperative and postoperative consideration of diet, antidiabetic medication regimens, and the likelihood of specific complications ...

AIMS: In this study, the effect of stress management training on glycemic control has been investigated in type 1 diabetic patients. METHODS: The participants were 60 type 1 diabetic patients (aged 16-30). 30 Subjects attended in 3-month stress management training classes during which the prescribed insulin remained constant, but the ...

OBJECTIVES: The study's objective was to audit current diet and disease management in a community-based sample of people with type 1 diabetes. METHODS: The study involved adults with type 1 diabetes and control subjects. Reported amounts of dietary intake were collected. Indices of diabetes control were determined by standard methods. ...

The benefits derived from regular physical activity include improved cardiovascular fitness, increased lean mass, improved blood lipid profile, enhanced psychosocial well-being, and decreased body adiposity. The benefits for children with diabetes may also include blood glucose control and enhanced insulin sensitivity. However, for these children, engagement in vigorous physical activity ...

Tropical forest people often suffer from the same processes that threaten biodiversity. An improved knowledge of what is important to local people could improve decision making. This article examines the usefulness of explicitly asking what is important to local people. Our examples draw on biodiversity surveys in East Kalimantan (Indonesian ...

The extent of interaction between smoking and diabetes has been under-appreciated. Smokers had more diabetes, and when diabetes patients smoke, the combined mortality effect was greater than either the addition or multiplication of these two medical problems. Patients seen in the office are usually more interested in reducing blood glucose ...

A study was conducted to investigate the efficiency of coagulation and flocculation processes for removing colour from a semi-aerobic landfill leachate from one of the landfill sites in Malaysia. Four types of coagulant namely aluminium (III) sulphate (alum), ferric (III) chloride, ferrous (II) sulphate and ferric (III) sulphate were studied ...

PURPOSE: The purpose of this study was to describe factors that facilitate or hinder diabetes self-management and elicit participants' preferences and recommendations about the essential components of a culturally competent diabetes self-management program. METHODS: Latino patients with type 2 diabetes and their family caregivers were interviewed in focus groups. Four ...

Lupine is a medicinal food plant with potential value in the management of diabetes. In white mice, extracts of seeds of the white lupine [Lupinus albus (L. termis L.)] were associated with increased tolerance to an oral glucose bolus. Antihyperglycemic activity was present in extracts of the whole seed but ...

OBJECTIVE: To review new pharmacologic therapies and technologies relevant to the management of diabetes and its complications. METHODS: New treatment options for diabetes, made available through research efforts during the past 2 decades, are discussed. RESULTS: Several new drugs and drug classes for the management of diabetes are under development, ...

Chronic diabetes requires systematic disease management that considers the patients' personal characteristics such as age and sex. The bureaucratic complexity of the Korean medical system lowers the efficiency of diabetes management. The present study developed a miniature blood glucose meter interfaced through the serial port of a cellular phone. The ...

Nutrition therapy is an integral part of the management of gestational diabetes mellitus (GDM). Four leading nutrition and diabetes organizations, the Canadian Diabetes Association (CDA), Dietitians of Canada (DC), Diabète Québec (DQ), and the Ordre professionnel des diététistes du Québec (OPDQ), formed a partnership to develop evidence-based nutrition practice guidelines ...

This paper presents results of an extensive field monitoring program of a proprietary stormwater treatment technology called the Stormvault. Analysis of 39 storms indicates that the system effectively and consistently reduced total suspended solids (TSS) average event mean concentration (EMC) from 70.6+/-17.0 mg/L to 41.2+/-3.7 mg/L. Results were comparable to ...

Assisting diabetes patients to self manage blood glucose test and insulin injection is of great importance for their healthcare. This study presented a PDA based system to manage the personal glucose level data interfaced with a small glucometer through a serial port. The data stored in the PDA can be ...

Dietary advice from health professionals can play a significant part in preventing and managing type 2 diabetes. Overweight and obesity are strongly associated with this condition, and individually tailored advice on weight loss and maintaining an appropriate weight are useful, together with encouragement to take appropriate exercise. Current thinking about ...

Water soluble cranberry-based phytochemical combinations with oregano, rosemary, and Rhodiola rosea were evaluated for total phenolic content, related antioxidant activity and inhibition of diabetes management-related alpha -glucosidase, pancreatic alpha-amylase inhibition, and hypertension-related ACE-I inhibitory activities. Water extracts of oregano had 114.9 mg/g DW of phenolics which was highest among all ...

Obesity and type-2 diabetes can be considered diseases of physical inactivity. Physically activity protects against type-2 diabetes through its positive effects on weight management and on the metabolic pathways involved in glycemic control that are not weight-dependent. Increasing physical activity is one of the most effective strategies both for preventing ...

BACKGROUND: Insulin is the recommend therapeutic agent of choice for the management of Cystic Fibrosis Related Diabetes (CFRD), despite only sub-optimal reductions in glycemic control and increased morbidity and mortality reported by centers using this agent. The newer insulin sensitizing agents demonstrated to have anti-inflammatory mechanisms may provide an alternative ...

OBJECTIVE: To identify the effectiveness of case management for community elderly with hypertension (HT), diabetes mellitus, and hypercholesterolemia (HC) (the so-called three highs). DESIGN AND SETTING: Secondary data of the first and 3-month-after visiting records were extracted from 33 Public Health Centers in Taiwan. PARTICIPANTS: Seven hundred and sixty-six clients ...

Developing a Web-based tool that involves the input, buy-in, and collaboration of multiple stakeholders and contractors is a complex process. Several elements facilitated the development of the Web-based Diabetes Indicators and Data Sources Internet Tool (DIDIT). The DIDIT is designed to enhance the ability of staff within the state-based Diabetes ...

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, which is also associated with a substantial risk of mortality and morbidity from stroke, thromboembolism, heart failure and hospitalisations. On a epidemiological basis, diabetes mellitus is commonly associated with AF. Nonetheless, AF is also associated with vascular disease and hypertension, ...

Large and usually unpredictable variation in species interaction strength has been a major roadblock to applying local experimental results to large-scale management and conservation issues. Recent studies explicitly considering benthic-pelagic coupling are starting to shed light on, and find regularities in, the causes of such large-scale variation in coastal ecosystems. ...

With the increasing number of diagnosed diabetics in the general population, dental health care providers can anticipate a greater number of diabetics in their practices. Familiarity with the systemic and oral signs and symptoms of DM may facilitate its diagnosis, and contribute to the quality of the individual's overall health. ...