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Bandula Steve S From the UCL Centre for Medical Imaging (S.B., S.P., S.A.T.), UCL Institute for Liver and Digestive Health, Division of Medicine (W.M.R., R.J.), and UCL Institute for Cardiovascular Science (J.C.M.), University College London, Gower St, London WC1E 6BT, England; and Department of Cellular Pathology, UCL Medical School, Royal Free Campus, London, England (A.R.H., - - 2014
Purpose To prospectively evaluate hepatic extracellular volume ( ECV extracellular volume fraction ) fraction measurement at equilibrium computed tomographic (CT) imaging compared with both fibrosis quantified with histologic analysis and the enhanced liver fibrosis panel ( ELF enhanced liver fibrosis ) in a cohort of patients with chronic hepatitis. Materials ...
Teke Memik M Department of Radiology, Medical School, Dicle University, Yeni┼čehir, Diyarbakir, 21280, Turkey, - - 2014
The main objective of this study was to describe the characteristic imaging features of cerebral and spinal hydatid disease (HD) in magnetic resonance imaging (MRI) and computed tomography (CT) in order to provide more effective differential diagnoses in endemic regions. We also aimed to use MRI and CT to evaluate ...
Krämer Christiane C Department of Gastroenterology and Hepatology, University of Cologne, Cologne, Germany; Department III of Internal Medicine, Heart Centre of the University of Cologne, Cologne, Germany. Electronic address: - - 2014
The present study was conducted to assess the diagnostic accuracy of Acoustic Structure Quantification (ASQ) ultrasound software in liver biopsy of patients with liver fibrosis and cirrhosis. Eighty patients (47 ± 14 y, 41 men) with chronic liver diseases underwent ultrasound examination of the liver and liver biopsy. In addition to the standard-care ...
Bender Benjamin B Department of Diagnostic and Interventional Neuroradiology, MR Research Group, University Hospital Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany, - - 2014
Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS) is a rare autosomal dominant disease caused by mutations within the colony stimulating factor 1 receptor (CSF1R) gene. While a small number of reports on imaging findings in routine MRI exist, reported imaging findings in DWI and spectroscopy are scarce, and limited to ...
Ichikawa Shintaro S Department of Radiology, University of Yamanashi, Yamanashi, - - 2014
To evaluate the use of intravoxel incoherent motion (IVIM) imaging for staging hepatic fibrosis, and compare its staging ability with that of magnetic resonance elastography (MRE). This study included 129 patients with pathologically staged liver fibrosis, and 53 patients with healthy livers. All patients underwent both MRE and IVIM imaging. ...
Chen Cuiyun C Shandong Medical Imaging Research Institute, Shandong University, Jinan, Shandong 250100, China; Department of Radiology, People's Hospital of Zhengzhou University, Zhengzhou, Henan 450003, - - 2014
The diagnosis of liver fibrosis is a difficult task at any time using conventional clinical imaging. Intravoxel incoherent motion (IVIM) can be used to investigate both diffusion and perfusion changes in tissues. This study was designed to determine the value of IVIM in the diagnosis and staging of liver fibrosis. ...
Paulin Gregory A GA Imaging Research Laboratories, Robarts Research Institute, University of Western Ontario, London, Canada; Department of Medical Biophysics, University of Western Ontario, London, - - 2014
To evaluate cystic fibrosis (CF) subjects over 4 years using (3) He magnetic resonance imaging (MRI), pulmonary function tests, and track hospitalization and physician visits. Five CF adults provided written informed consent to an approved protocol and underwent MRI, spirometry, and plethysmography at baseline, 7 days, and 4 ± 1 years later. ...
Tiddens Harm A W M HA Department of Pediatric Pulmonology, Erasmus MC-Sophia Children's Hospital, Wytemaweg 80, 3015, CN, Rotterdam, The Netherlands, - - 2014
Despite our current treatment, many cystic fibrosis (CF) patients still show progressive bronchiectasis and small airways disease. Adequate detection and monitoring of progression of these structural abnormalities is needed to personalize treatment to the severity of CF lung disease of the patient. Chest computed tomography (CT) is the gold standard ...
Lamb Peter - - 2014
Quantifying the amount and characterizing the severity of liver fibrosis has direct clinical implications for patient diagnosis and treatment. Although this task is often accomplished through liver biopsy, the clinical utility of this procedure is disputed. Several imaging-based techniques for staging liver fibrosis have emerged, such as magnetic resonance elastography ...
Gong Wu-Xian WX Shandong Medical Imaging Research Institute, Shandong University, Jinan 250012, China. Electronic address: - - 2014
The aim of this study was to analyze HRCT and MRI findings in patients with X-linked non-syndromic deafness and a POU3f4 mutation. HRCT and MRI data of four patients (males, 2-19 years old) with a POU3f4 mutation were collected and a retrospective review was performed. Cochlea, internal auditory canal (IAC), ...
Goto Taichi - - 2014
Vacuum annealed polycrystalline cerium substituted yttrium iron garnet (CeYIG) films deposited by radio frequency magnetron sputtering on non-garnet substrates were used in nonreciprocal racetrack resonators. CeYIG annealed at 800°C for 30 min provided a large Faraday rotation angle, close to the single crystal value. Crystallinity, magnetic properties, refractive indices and ...
Choi Seung Hee SH Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
Several imaging-based indices were constructed quantitatively using the emphysema index (EI) and fibrosis score (FS) on high-resolution computed tomography (HRCT). We evaluated the ability of these indices to predict mortality compared to physiologic results. Additionally, prognostic predictive factors were compared among subgroups with biopsy-proven fibrotic idiopathic interstitial pneumonia (IIP) (biopsy-proven ...
Chikenji Takako T Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, United States of - - 2014
Carpal tunnel syndrome (CTS) is an idiopathic disease that results from increased fibrosis of the subsynovial connective tissue (SSCT). A recent study found overexpression of both transforming growth factor-β (TGF-β) and connective tissue growth factor (CTGF) in the SSCT of CTS patients. This study investigated TGF-β and CTGF expression in ...
Zarei Sara S Computational Science Research Center, San Diego State University, San Diego, California, United States of - - 2014
Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) scan are the two ubiquitous imaging sources that physicians use to diagnose patients with Cystic Fibrosis (CF) or any other Chronic Obstructive Pulmonary Disease (COPD). Unfortunately the cost constraints limit the frequent usage of these medical imaging procedures. In addition, even though ...
Kim Honsoul H Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Republic of - - 2014
The diagnosis and monitoring of liver fibrosis is an important clinical issue; however, this is usually achieved by invasive methods such as biopsy. We aimed to determine whether histogram analysis of hepatobiliary phase images of gadoxetic acid-enhanced magnetic resonance imaging (MRI) can provide non-invasive quantitative measurement of liver fibrosis. This ...
Lu Pu-Xuan PX Department of Radiology, The Shenzhen No. 3 People's Hospital, Guangdong Medical College, Shenzhen, - - 2014
This study was aimed to determine whether pure molecular-based diffusion coefficient (D) and perfusion-related diffusion parameters (perfusion fraction f, perfusion-related diffusion coefficient D*) differ in healthy livers and fibrotic livers through intra-voxel incoherent motion (IVIM) MR imaging. 17 healthy volunteers and 34 patients with histopathologically confirmed liver fibrosis patients (stage ...
Notni Johannes - - 2013
A killer application? Recently, fully integrated full-body positron-emission tomography (PET) and magnetic-resonance imaging (MRI) scanners were brought to market, allowing simultaneous recording of complementary 3D data sets. By using bimodal PET/MRI probes (see figure), in vivo 3D mapping of various parameters with medical relevance could become feasible.
Strauch Frederick W - - 2012
An all-resonant method is proposed to control the quantum state of superconducting resonators. This approach uses a tunable artificial atom linearly coupled to resonators, and allows for efficient routes to Fock state synthesis, qudit logic operations, and synthesis of NOON states. This resonant approach is theoretically analyzed, and found to ...
Ito Katsuhiko - - 2012
The larval head cuticle and anal plates of the silkworm mutant cheek and tail spot (cts) have chocolate-colored spots, unlike the entirely white appearance of the wild-type (WT) strain. We report the identification and characterization of the gene responsible for the cts mutation. Positional cloning revealed a cts candidate on ...
Wayakanon Praween - - 2012
Connexin 43 (Cx43) is a major gap junction (GJ) protein found in many mammalian cell types. The C-terminal (CT) domain of Cx43 has unique characteristics in terms of amino acid (aa) sequence and its length differs from other connexins. This CT domain can be associated with protein partners to regulate ...
Li Guan-Wu - - 2011
PURPOSE: To explore the evidence of regular alteration of bone quality in osteoporosis dynamically examined by MRS and micro-CT, comparing with histopathology. METHODS: Forty rabbits were allocated into two groups. Group A were used as sham. Group B underwent bilateral ovariectomy (OVX) combined with daily intramuscular methylprednisolone, underwent MR spectroscopy, ...
Li Yonggang - - 2011
Magnetic Fe(2)O(3) nanorods with low cell toxicity were successfully synthesized via a wet-chemical method. In vivo studies with a rabbit model show that the nanorods exhibit excellent T(2) signal enhancement. This work demonstrates that magnetic nanorods may provide a new type of MR enhancement agent for use in biomedical applications.
Kono Hitoshi - - 2011
  To clarify the mechanism of osteoporosis in adolescent idiopathic scoliosis (AIS), we investigated radiological and histological changes in the cervical vertebrae of a chicken thoracic scoliosis model. Forty newly hatched broiler chicks were randomly divided into four equal groups: sham-operated chickens serving as control (CON), pinealectomized chickens (PNX), sham-operated ...
Cho Eun-Jin - - 2011
OBJECTIVES:: To investigate the efficiency of magnetic resonance imaging (MRI) contrast agents employing vascular endothelial growth factor (VEGF121)/rGel conjugated MnFe2O4 nanocrystals for imaging of neovasculature using a bladder tumor model. MATERIALS AND METHODS:: VEGF121/rGel was conjugated to MnFe2O4 nanoparticles (MNPs). The targeting efficiency and detection capability of the VEGF121/rGel-MNPs were ...
Tsai Hsin-Yu - - 2011
In computed tomography (CT), the term "artifact" is applied to any systematic discrepancy between the CT numbers in the reconstructed image and the true attenuation coefficients of the object. A partial ring artifact in cardiac CT has a unique pattern and has not been previously reported in real clinical practice. ...
Sahul Zakir H ZH Experimental Nuclear Cardiology Laboratory, Yale University School of Medicine, New Haven, CT 06520-8017, - - 2011
Matrix metalloproteinases (MMPs) are known to modulate left ventricular (LV) remodeling after a myocardial infarction (MI). However, the temporal and spatial variation of MMP activation and their relationship to mechanical dysfunction after MI remain undefined. MI was surgically induced in pigs (n = 23) and cine magnetic resonance (MR) and ...
Parker Scott L - - 2011
Object Pedicle screws provide efficient stabilization along all 3 columns of the spine, but they can be technically demanding to place, with malposition rates ranging from 5% to 10%. Intraoperative electromyographic (EMG) monitoring has the capacity to objectively identify a screw breaching the medial pedicle cortex that is in proximity ...
Tsalafoutas Ioannis A - - 2011
PURPOSE: To experimentally investigate the effect of the scan field of view (SFOV) selection and table height settings on the Computed Tomography Dose Index (CTDI) and the implications concerning patient effective and skin dose. METHODS: Air-kerma length product (AKLP) measurements were carried out in a helical CT scanner using a ...
Houtz Carlton G - - 2011
Evaluate the accuracy for shoulder magnetic resonance imaging (MRI) interpretations of typical community radiologists and compare this to selected fellowship trained musculoskeletal radiologists. The MRIs of 104 shoulders of 100 consecutive different patients who had undergone shoulder arthroscopy by a single surgeon were included in this prospective study. The 104 ...
Eyibilen Ahmet - - 2011
Laryngoptosis is a rare anomaly of the larynx. The larynx is localized in a position lower than its normal position. A 15-year-old boy presented with hoarseness of voice. Physical examination showed that the larynx was in an abnormal position. There were no palpated tracheal rings. A low-pitched monotonic voice was ...
Shah Sundeep - - 2011
Littoral cell angioma (LCA) is a rare primary splenic vascular tumor arising from the littoral cells that line the splenic sinuses of the red pulp. Definitive diagnosis of this entity depends on histology and immunochemical studies, for which splenectomy is usually performed. We present three image-guided percutaneous core biopsy proven ...
Villa Chiara - - 2011
AIM: To evaluate the diagnostic ability of contrast-enhanced Magnetic Resonance Imaging (MRI) in assessment of the activity of perianal fistulas in Crohn's disease (CD) patients, compared to clinical data. MATERIALS AND METHODS: Fifty CD patients (25 men; mean[SD] age: 40.4[12.6] years) with known or suspected perianal fistulas underwent perianal space ...
Liu Shao-Cheng - - 2011
For around 50 years, various approaches to the vidian neurectomy have been advocated. This indicates that there is no single surgical technique that is superior to all others. In this report, we analyze the included angle between the posterior end of middle turbinate and the anterior opening of the vidian canal. ...
Campana S - - 2011
Biomechanical modelling of the spine is of high clinical significance, either for implant evaluation or for surgery planning. Nevertheless, assessment of patient specific material properties still remains an issue, especially the viscoelastic characteristics of lumbar intervertebral discs (IVD). MRI, a dedicated system for IVD examination, provides a signal that is ...
Sansare K - - 2011
X-rays were discovered in 1895 and since then much has been written about Wilhelm Roentgen and the events surrounding the discovery. However, there have been only scattered references in the literature about the early workers who dedicated their life, and death, to X-rays. Radiology has come of age since then. ...
Uchiyama Hitoshi T - - 2011
To comprehend figurative utterances such as metaphor or sarcasm, a listener must both judge the literal meaning of the statement and infer the speaker's intended meaning (mentalizing; Amodio and Frith, 2006). To delineate the neural substrates of pragmatic comprehension, we conducted functional magnetic resonance imaging (fMRI) with 20 normal adult ...
Rapoport Natalya N Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, USA. - - 2011
Perfluorocarbon nanoemulsions can deliver lipophilic therapeutic agents to solid tumors and simultaneously provide for monitoring nanocarrier biodistribution via ultrasonography and/or (19)F MRI. In the first generation of block copolymer stabilized perfluorocarbon nanoemulsions, perfluoropentane (PFP) was used as the droplet forming compound. Although manifesting excellent therapeutic and ultrasound imaging properties, PFP ...
Mohammed El Romyssa - - 2011
Abstract The diagnosis and management of spontaneous otogenic pneumocephalus with literature review is described. A young sportsman experienced headache and fluctuating mass in his occiput during increased physical activity. A large extradural intracranial pneumocephalus with corresponding emphysema was imaged on a CT scan. Transmastoid identification and plugging of temporal bone ...
Pourat Nadereh - - 2011
BACKGROUND:: Chlamydia trachomatis (CT) guidelines call for annual screening of all sexually active young females. In previous studies, Medicaid health maintenance organizations (HMOs) did not consistently recommend CT and other sexually transmitted disease guidelines, but physicians with HMO practices were more likely to comply with guidelines than those without HMO ...
Guignand D - - 2011
In case of hindfoot pain, diagnosis of calcaneonavicular tarsal coalition may be missed on X-ray due to the absence of any visible synostosis. All other possible etiologies (too-long anterior process (TLAP) of the calcaneum, synchondrosis, syndesmosis) must be investigated. The literature tends to recommend imaging associating standard X-ray and CT, ...
Lim Se-Woong - - 2011
RATIONALE AND OBJECTIVES: The aim of this study was to assess the feasibility of thermally cross-linked superparamagnetic iron oxide nanoparticle contrast (TCL-SPION) in magnetic resonance (MR) imaging (MRI) for the detection of lymph node metastasis in experimental model. MATERIALS AND METHODS: B16F1 human melanoma cells were subcutaneously injected into the ...
Shu Yilai - - 2011
OBJECTIVES/HYPOTHESIS: To investigate the potential usefulness of indirect computed tomography lymphography (CT-LG) with iopamidol in the detection of cervical lymph node metastases in a VX2 rabbit tongue cancer model. STUDY DESIGN: Randomized controlled trial. METHODS: Thirty-seven rabbits were randomly divided into control (n = 7) and tongue tumor-bearing (n = ...
Bhattacharjee Shomoresh - - 2011
Recent publications have highlighted the use of fluorine 18 fluorodeoxyglucose (F-FDG) positron emission tomography (PET) as a moderately sensitive, noninvasive diagnostic test for medium- and large-vessel vasculitis. We report the atypical case of a patient with biopsy-proven granulomatous vasculitis of the aorta in addition to a non-small cell lung cancer, ...
Cramer Gregory D - - 2011
This project determined the feasibility of conducting larger studies assessing the relationship between cavitation and zygapophyseal (Z) joint gapping following spinal manipulative therapy (SMT). Five healthy volunteers (average age, 25.4 years) were screened and examined against inclusion and exclusion criteria. High-signal magnetic resonance imaging (MRI) markers were fixed to T12, ...
Sormani Mp - - 2010
Recent studies have provided evidence for using magnetic resonance imaging (MRI) active lesions as surrogate for relapses and disability progression in multiple sclerosis (MS). However, the validity of MRI metrics as surrogate endpoints in MS is controversial. Furthermore, the extrapolation of previous results to novel therapies is not warranted. We ...
Amiri Houshang - - 2011
We report cell endocytosis, drug release, NMR relaxometry and in vitro MRI studies on a novel class of superparamagnetic colloidal nanocrystal clusters (CNCs) with various biocompatible coatings. It is shown that the transverse relaxivity r2, the parameter representing the MRI efficiency in negative contrast agents, for the PVA-coated, PEGF-coated, and ...
Ray Simon - - 2010
Functional mitral regurgitation (MR) is common, clinically important, and mechanistically complex. Its assessment by echocardiography can be challenging, and particular care is needed in the quantification of severity. Echocardiographers need to be aware of the potential limitations of flow convergence and vena contracta methods in assessing severity and alert to ...
Niggemann Pascal - - 2010
The aim was to investigate the effect of patient position on the size of the cisterna chyli using positional MRI. The cisterna chyli is usually the only large lymphatic vessel that can be found on cross-sectional imaging. Not much is known about its postural behavior. However, animal studies suggest that ...
Rizzo Julie A - - 2010
As more endovascular interventions are being used in the carotid circulation, including carotid angioplasty and stenting, a reliable imaging modality is needed to follow the results. Currently, duplex ultrasonography, magnetic resonance angiography (MRA), and angiography are the main modalities used. This report presents a case of MRA and duplex ultrasonography ...
Meng Jie - - 2010
Endohedral metallofullerenes, a novel form of carbon-related nanomaterials, currently attract wide attention for their potential applications in biomedical fields such as therapeutic medicine. Most endohedral metallofullerenes are synthesized using C60 or higher molecular weight fullerenes because of the limited interior volume of fullerene. It is known that the encapsulated metal ...
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