Search Results
Results 101 - 150 of 892
1 2 3 4 5 6 7 8 9 10 >
Burton Emma J EJ Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, UK. - - 2012
The objective of this study was to determine the neuropathological correlates of regional medial temporal lobe volume measures on magnetic resonance imaging (MRI) in subjects with Lewy body dementia (LBD). Twenty-three autopsy-confirmed LBD cases with an MRI scan close to death (mean 1.5 years) were studied. MRI-based volumetric measures were ...
Dechambenoit Pierre - - 2011
Combining porosity and magnetic ordering in a single material presents a significant challenge since magnetic exchange generally requires short bridges between the spin carriers, whereas porosity usually relies on the use of long diamagnetic connecting ligands. Despite this apparent incompatibility, notable successes have been achieved of late in generating truly ...
Konstantopoulos Aristides - - 2011
To quantify the human corneal inflammatory response in treated bacterial keratitis with long-wavelength anterior segment optical coherence tomography (AS-OCT). Patients with clinically suspected bacterial keratitis were recruited from the corneal service at Southampton Eye Unit, UK. Patients underwent AS-OCT and slit-lamp examination on presentation (day 0) and days 3, 7, ...
Larkin Ann M - - 2011
Purpose. We quantify the additional radiation exposure in terms of effective dose incurred by patients in the CT portion of SPECT/CT examinations. Methods. The effective dose from a variety of common nuclear medicine procedures is calculated and summarized. The extra exposure from the CT portion of the examination is summarized ...
Schmitz-Valckenberg Steffen - - 2011
To analyze outer retinal changes within the atrophic lesion in patients with geographic atrophy (GA) secondary to age-related macular degeneration. Twenty-one simultaneously obtained fundus autofluorescence (FAF, excitation, 488 nm; emission, 500-700 nm) and spectral-domain optical coherence tomography (SD-OCT) scans (Spectralis HRA+OCT; Heidelberg Engineering, Heidelberg, Germany) of 21 GA patients (mean ...
Iida Hiroji - - 2011
The general method of measuring the half-value layer (HVL) for X-ray computed tomography (CT) using square aluminum-sheet filters is inconvenient in that the X-ray tube has to be set to stationary mode. To avoid this inconvenience, we investigated a new method using copper-pipe filters that cover the ionization chamber (copper-pipe ...
Saranu Srinivasa - - 2011
Magnetic nanoparticles are promising candidates for next generation high density magnetic data storage devices. Data storage requires precise control of the magnetic properties of materials, in which the magnetic anisotropy plays a dominant role. Since the total magneto-crystalline anisotropy energy scales with the particle volume, the storage density in media ...
Zuo Xi-Nian - - 2011
Neuroimaging community usually employs spatial smoothing to denoise magnetic resonance imaging (MRI) data, e.g., Gaussian smoothing kernels. Such an isotropic diffusion (ISD) based smoothing is widely adopted for denoising purpose due to its easy implementation and efficient computation. Beyond these advantages, Gaussian smoothing kernels tend to blur the edges, curvature ...
Callahan Jason J Peter MacCallum Cancer Centre, Centre for Molecular Imaging, St Andrews Place, East Melbourne, Victoria, Australia. - - 2011
Lesion movement during positron emission tomography (PET) scan acquisition due to normal respiration is a common source of artefact. A PET scan is acquired in multiple couch positions of between 2 and 5 min duration with the patient breathing freely. A PET-avid lesion will become blurred if affected by respiratory ...
Zhang Yi Y University of TexasHealth Science Center, San Antonio, TX, - - 2011
To demonstrate blood oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) of vascular oxygenation changes in normal, unanesthetized human retinas associated with oxygen and carbogen challenge. MRI was performed with a 3-T human scanner and a custom-made surface-coil detector on normal volunteers. BOLD MRI with inversion recovery was used to suppress ...
Benavente-Pérez Alexandra - - 2010
To evaluate the repeatability and reproducibility of subfoveal choroidal thickness (CT) calculations performed manually using optical coherence tomography (OCT). The CT was imaged in vivo at each of two visits on 11 healthy volunteers (mean age, 35.72 ± 13.19 years) using the spectral domain OCT. CT was manually measured after ...
Saikia Parykshit - - 2010
To describe a presentation of painless posterior scleritis. This study was an interventional case report. An 18-year-old boy was admitted to the authors' clinic with symptoms of low degree of vision and no ocular pain. Ophthalmologic examination, ocular ultrasonography, magnetic resonance imaging, fundus fluorescein angiography (FFA), optical coherence tomography (OCT), ...
Ichhpujani Parul - - 2010
The iStent (Glaukos Corporation, Laguna Hills, CA) is a 1-mm, titanium trabecular bypass stent implanted across the inner wall of Schlemm's canal under direct gonioscopy. This study was designed to determine the best modality to identify iStent placement when gonioscopic visualization is not possible. In this in vitro study on ...
Moon Sucbei S Beckman Laser Institute, University of California, Irvine, Irvine, CA 92612, - - 2010
A forward-view optical coherence tomography (OCT) scanning catheter has been developed based on a fiber-cantilever piezotube scanner by using a semi-resonant scan strategy for a better scan performance. A compact endoscope catheter was fabricated by using a tubular piezoelectric actuator with quartered electrodes in combination with a resonant fiber cantilever. ...
Basiruddin S K - - 2010
A magnetic quantum dot (MQD) based cellular nanoprobe, composed of a magnetic oxide nanoparticle component and a quantum dot component, has been synthesized and used for both imaging and separation. The successful synthesis is based on a reverse micelle based polyacrylate coating in the presence of component nanoparticles, followed by ...
Lim Eun-Kyung - - 2010
We fabricated multimode nanoprobes for acquisition of biological information at different object levels, i.e., in vivo detection and ex vivo validation for characterizing tumor angiogenesis. Fluorescent magnetic nanoprobes (FMNPs) were synthesized by using amphiphilic pyrenyl polyethylene glycol (Py-PEG) and superparamagnetic MnFe(2)O(4) nanocrystals (MNCs). Py-PEG, which is synthesized by conjugation of ...
Nair Govind G Graduate School of Biomedical Science, University of Massachusetts Medical School, Worcester, MA, - - 2011
The retina is nourished by two unique (retinal and choroidal) circulations. The lack of depth-resolved blood volume (BV) imaging techniques hampers investigation of vascular-specific regulation of the retina in vivo. This study presents a high-resolution, laminar-specific magnetic resonance imaging (MRI) study to image retinal and choroidal BVs, their responses to ...
Kim Hoe Suk - - 2010
A combination of reporter genes for magnetic resonance imaging (MRI) and optical imaging can provide an additional level of noninvasive and quantitative information about biological processes occurring in deep tissues. We developed a bimodal lentiviral vector to monitor deep tissue events using MRI to detect myc-tagged human ferritin heavy chain ...
Kiilgaard Jens Folke - - 2011
Background:  Intraocular silicone oil may migrate into the optic nerve or the cerebral ventricles, but little is known about the frequency of these events. The aim of this prospective neuroimaging study was to determine the frequency of extraocular silicone oil migration in humans operated for retinal detachment. Methods:  Nineteen patients ...
Jańczewski Dominik - - 2011
Fluorescent optical probes have been intensively used in the area of bio-imaging. In this review article, we describe the recent advancements in the synthesis and application of bimodal magnetic-fluorescent probes for bioimaging. The bimodal probes consist of fluorescent [semiconducting quantum dots (e.g., CdSe/ZnS) or rare-earth doped (e.g., NaYF(4) :Yb,Er)] nanoparticles ...
Howes Philip - - 2010
Hybrid nanoparticles which incorporate multiple functionalities, such as fluorescence and magnetism, can exhibit enhanced efficiency and versatility by performing several tasks in parallel. In this study, magnetic-fluorescent semiconductor polymer nanospheres (MF-SPNs) have been synthesized by encapsulation of hydrophobic conjugated polymers and iron oxide nanoparticles in phospholipid micelles. Four fluorescent conjugated ...
Tseng Hung-Yu - - 2010
Preparation of a high-concentration Au nanoring (NR) water solution and its applications to the enhancement of image contrast in optical coherence tomography (OCT) and the generation of the photothermal effect in a bio-sample through localized surface plasmon (LSP) resonance are demonstrated. Au NRs are first fabricated on a sapphire substrate ...
Byrne A J - - 2010
Dry skin (also known as xerosis) is a cutaneous reaction pattern indicative of abnormal desquamation, which has not only cosmetic considerations, but can also lead to the penetration of irritants and allergens through the stratum corneum (SC). Over the last few decades, our understanding of the structure, composition, formation and ...
Gros Stephanie J - - 2010
We describe the development of an aggressive orthotopic metastatic model of esophageal cancer, which is visualized in real time with combined magnetic resonance imaging (MRI) and fluorescence imaging. The aim of the study was to describe the development of a novel model of metastatic tumor disease of esophageal carcinoma and ...
Wan Jiaqi - - 2010
Bifunctional nanoprobes with both magnetic and optical contrast have been developed for ultra-sensitive brain tumor imaging at the cellular level. The nanoprobes were synthesized by simultaneously incorporating a magnetite nanoparticle cluster and fluorescence dyes into silica encapsulation by a sol-gel approach under ultrasonic treatment. The nanoprobes maintain superparamagnetic behavior at ...
You Youngmin Y Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, - - 2010
A paramagnetic manganese complex of a fluorescein-based probe affords a dual-modality zinc sensor featuring an improved fluorescence dynamic range and an MRI readout.
Khurana Rahul N - - 2010
PURPOSE: To compare fluorescein leakage from choroidal neovascularization (CNV) with signs of intraretinal or subretinal fluid on time-domain optical coherence tomography (TD-OCT) and spectral-domain optical coherence tomography (SD-OCT) in patients receiving anti-vascular endothelial growth factor (anti-VEGF) therapy for CNV caused by age-related macular degeneration (AMD). DESIGN: Retrospective, consecutive case series. ...
Tanitame Keizo - - 2010
PURPOSE: To compare a half-Fourier single-shot rapid acquisition with relaxation enhancement (RARE) sequence with a balanced steady-state free precession (b-SSFP) sequence in the evaluation of the eye using magnetic resonance (MR) microscopy imaging and to clarify the usefulness of RARE microscopy imaging in evaluating nonoperative glaucoma patients and patients who ...
Li Yan Y Center for Ophthalmic Optics and Lasers, Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, - - 2010
To evaluate the repeatability of Fourier-domain optical coherence tomography (OCT) pachymetric mapping and compare central corneal thickness (CCT) measurements by OCT, ultrasound pachymetry, and scanning-slit tomography. Doheny Eye Institute, University of Southern California, Los Angeles, California, USA. A Fourier-domain OCT system was used to map the corneal thickness in normal ...
John Renu R Department of Bioengineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, - - 2010
Dynamic magnetomotion of magnetic nanoparticles (MNPs) detected with magnetomotive optical coherence tomography (MM-OCT) represents a new methodology for contrast enhancement and therapeutic interventions in molecular imaging. In this study, we demonstrate in vivo imaging of dynamic functionalized iron oxide MNPs using MM-OCT in a preclinical mammary tumor model. Using targeted ...
Guo Kevin K Department of Radiology, Washington University, St. Louis, MO 63110, - - 2010
A new gadolinium chelating NIR fluorescent molecular probe increases T(1) relaxivity of water protons, facilitating combined optical and magnetic resonance imaging.
Roberts David W - - 2011
The aim of this study was to investigate the relationships between intraoperative fluorescence, features on MR imaging, and neuropathological parameters in 11 cases of newly diagnosed glioblastoma multiforme (GBM) treated using protoporphyrin IX (PpIX) fluorescence-guided resection. In 11 patients with a newly diagnosed GBM, δ-aminolevulinic acid (ALA) was administered to ...
Bear David M - - 2010
Optical coherence tomography (OCT) and T2 mapping are emerging clinical imaging technologies with potential to detect subsurface changes in cartilage retaining a macroscopically intact articular surface. This study tests the hypothesis that OCT correlates with magnetic resonance imaging (MRI) T2 values, and that OCT signal is sensitive to cartilage matrix ...
Hong Samin - - 2010
PURPOSE: To verify the effect of the scan angle of the optic nerve head (ONH) on measurements of peripapillary retinal nerve fiber layer (RNFL) thickness by using spectral-domain optical coherence tomography (OCT). METHODS: Both eyes of 64 healthy volunteers were scanned by the optic disc cube 200 x 200 scan ...
Cooper Michael L - - 2010
There is considerable research activity in multiresonator optical circuits in silicon photonics, e.g., for higher-order filters, advanced modulation format coding/decoding, or coupled-resonator optical waveguide delay lines. In diagnostics of such structures, it is usually not possible to measure each individual microring resonator without adding separate input and output waveguides to ...
Zheng Kathy - - 2010
Current treatments for osteoarthritis are pain relief and total joint arthroplasty. There is a clinical need for early osteoarthritis diagnostic methods for potential preventive interventions. The resolution achieved with radiography, magnetic resonance imaging (MRI), and arthroscopy is too limited for the assessment of early disease. The high resolution, small fiber-optic ...
Davis Scott C SC Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA. - - 2010
This report demonstrates the diagnostic potential of magnetic resonance imaging (MRI)-coupled fluorescence molecular tomography (FMT) to determine epidermal growth factor receptor (EGFR) status in brain cancer. Two orthotopic glioma xenograft models were used in this study: one represented high EGFR expression and the other low expression. Nude mice were inoculated ...
Guo Hai - - 2010
Rational combination of different functional lanthanide materials within a single nanocrystal presents a feasible way to develop a multifunctional nanoplatform for various biomedical applications. The conventional methods of synthesizing and integrating two kinds of material together generally involve laborious procedures, whilst codoping different functional ions inside a single lanthanide nanocrystal ...
Han Ian C - - 2010
To characterize the types and frequencies of image artifacts associated with macular scanning using 2 common spectral-domain optical coherence tomography (SD OCT) instruments and to evaluate the impact of artifacts on foveal thickness measurements. Retrospective, observational chart review. For the Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA), scans of 98 ...
Schwarze Thomas - - 2010
The [6.6](9,10)anthracenophane 1 (Scheme 1) is a selective fluoroionophore for the detection of PdCl(2) with a large fluorescence enhancement factor (I/I(0) > 250).
Barber W C WC DxRay Inc., 19355 Business Center Dr. Suite 10, Northridge, CA 91324, USA. - - 2010
Initial results from a novel dual modality preclinical imager which combines non-contact fluorescence tomography (FT) and x-ray computed tomography (CT) for preclinical functional and anatomical in vivo imaging are presented. The anatomical data from CT provides a priori information to the FT reconstruction to create overlaid functional and anatomical images ...
Sun Pan P Department of Chemistry, Northeastern University, Shenyang 110004, PR - - 2010
The synthesis of a new kind of magnetic, fluorescent multifunctional nanoparticles (approximately 30 nm in diameter) was demonstrated, where multiple fluorescent CdTe quantum dots (QDs) are covalently linked to and assembled around individual silica-coated superparamagnetic Fe(3)O(4) nanoparticles and active carboxylic groups are presented on the surface for easy bioconjugation with ...
Danielli Amos - - 2010
A magnetic modulation biosensing system (MMB) [1,2] rapidly and homogeneously detected biological targets at low concentrations without any washing or separation step. When the IL-8 target was present, a 'sandwich'-based assay attached magnetic beads with IL-8 capture antibody to streptavidin coupled fluorescent protein via the IL-8 target and a biotinylated ...
Garc?a-Alonso Javier - - 2010
Saccharomyces cerevisiae containing fluorescent markers are ideal candidates for applications in microfluidic screening systems as fluorescence signal is emitted without the need of additional reagents. Here we develop a method for magnetic functionalization of such cells which allows their handling and immobilization in micro-screening devices. After exposure of the magnetized ...
Patra M - - 2009
Electrical transport properties as a function of magnetic field and time have been investigated in polycrystalline, Nd(0.84)Sr(0.16)CoO(3). A strong exchange bias (EB) effect is observed associated with the fairly large intragranular magnetoresistance (MR). The EB effect observed in the MR curve is compared with the EB effect manifested in the ...
Zhu Zhenshu - - 2010
Paclitaxel (PTX)-loaded poly(N-vinylpyrrolidone)-b-poly(epsilon-caprolactone) (PVP-b-PCL) nanoparticles with high drug payload were successfully prepared by a modified nano-precipitation method and characterized by transmission electron microscopy (TEM), atomic force microscopy (AFM), dynamic light scattering (DLS) and zeta potential. The satisfactory drug loading content (>25%) and high encapsulation efficiency (>85%) were achieved. The in ...
Hellgren Kerstin - - 2009
PURPOSE: We aimed to evaluate visual fields (VFs) and optic disc morphology in very low birthweight (VLBW) adolescents compared with age- and gender-matched controls, and to relate the findings to magnetic resonance imaging (MRI) results. METHODS: Fifty-nine VLBW adolescents and 55 age- and gender-matched controls with normal birthweight were examined. ...
Setua Sonali - - 2010
Targeted cancer imaging using rare-earth oxide nanocrystals, free from heavy metals (Cd, Se, Te, Hg and Pb), showing bright red-fluorescence and magnetic resonance imaging (MRI) is presented. Y(2)O(3) nanocrystals (YO NC) doped in situ with fluorescent (Eu(3+)) and paramagnetic (Gd(3+)) impurities and conjugated with a potential cancer targeting ligand, folic ...
Sturzu Alexander - - 2010
The extracellular glycoprotein Tenascin-C (TN-C) is highly upregulated in gliomas. Therefore, many chemotherapies with radiolabeled antibodies against TN-C have been performed. However, TN-Cs binding partner Syndecan-4 did not play any role as a therapeutic or imaging target in gliomas. We constructed an imaging compound containing the magnetic resonance imaging (MRI) ...
Sadda Srinivas R - - 2010
To investigate the relationship between B-scan density and retinal thickness measurements obtained by spectral domain optical coherence tomography (SDOCT) in eyes with retinal disease. Data were collected from 115 patients who underwent volume OCT imaging with Cirrus HD-OCT using the 512 x 128 horizontal raster protocol. Raw OCT data, including ...
1 2 3 4 5 6 7 8 9 10 >