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Sangfelt Per P Gastroenterology Research Group, Department of Medical Sciences, Uppsala University Hospital, - - 2014
Despite high risk of cholangiocellular adenocarcinoma (CCA) it is unclear how surveillance of patients with primary sclerosing cholangitis (PSC) should be performed. We evaluated a follow-up algorithm of brush cytology and positron emission tomography/computed tomography with [18F]fluorodeoxyglucose ([18F]FDG-PET/CT), measured as the maximum standardized uptake values normalized to the liver background ...
Ratnarajah Nagulan N Department of Biomedical Engineering, National University of Singapore, - - 2014
Accurate and consistent segmentation of brain white matter bundles at neonatal stage plays an important role in understanding brain development and detecting white matter abnormalities for the prediction of psychiatric disorders. Due to the complexity of white matter anatomy and the spatial resolution of diffusion-weighted MR imaging, multiple fiber bundles ...
Mohandas Aravind A 1 Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins School of Medicine, 601 N Caroline St, JHOC 3235, Baltimore, MD - - 2014
OBJECTIVE. FDG PET/CT has a growing role in the diagnosis and management of nasopharyngeal carcinoma (NPC). FDG PET has greater efficacy for N and M staging than other modalities, which enables the treating oncologists to select the appropriate mode of treatment. FDG PET/CT helps in radiation therapy planning, provides valuable ...
Chiaravalloti Agostino A Department of Biomedicine and Prevention, University Tor Vergata, Rome (AC, RD, CRC, LT, MC, MG, AO, GS, OS); Azienda Ospedaliera S. Coce e Carle, Hematology, Cuneo (AG); and IRCCS Neuromed, Pozzilli (OS), - - 2014
The objective of this study was to compare the diagnostic accuracy of positron emission tomography/low-dose computed tomography (PET/ldCT) versus the same technique implemented by contrast-enhanced computed tomography (ceCT) in staging Hodgkin's disease (HD).Forty patients (18 men and 22 women, mean age 30 ± 9.6) with biopsy-proven HD underwent a PET/ldCT study for ...
Agate Laura L Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Via Paradisa 2, 56127, Pisa, Italy, - - 2014
DTC patients having detectable Tg and negative post-therapeutic (131)I-WBS have to be investigated by different imaging techniques to detect metastases. Comparison of neck US, CT and [18F]-FDG PET scan. In 49 DTC patients with biochemical disease, neck was examined by US, CT and [18F]-FDG PET. FNA was performed and Tg ...
Matsuzaki Ippei I Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, - - 2014
Magnetic anchor-guided endoscopic submucosal dissection (MAG-ESD) was developed to reduce adverse events such as bleeding and perforation and to facilitate ESD. However, the external electromagnet required miniaturization to make it suitable for daily clinical practice. To evaluate the feasibility of simplified MAG-ESD using permanent magnets. Case series. Nagoya University Hospital. ...
Santhanam Prasanna P Section of Endocrinology, Department of Internal Medicine, Joan C Edwards School of Medicine, Marshall University, 25701, - - 2014
(18) F-FDOPA (6-[18F]-L-fluoro-L-3, 4-dihydroxyphenylalanine) based PET/CT imaging can be a useful tool for the detection of different neuroendocrine tumours (NETs). (18) F-FDOPA is taken up into the cells via the neutral amino acid transporter (LAT1/4F2hc). This transporter is also coupled to the mammalian target of rapamycin (mTOR) signalling pathway. (18) ...
Even-Sapir Einat E Department of Nuclear Medicine, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, Tel-Aviv 64239, Israel. Electronic address: - - 2014
Production of (18)F-labeled tracers, including (18)F-fluoride, has been simplified, and bone imaging using (18)F-fluoride PET with computed tomography (PET/CT) is relevant once again. (18)F-Fluoride PET/CT imaging should be considered for the assessment of bone abnormality in clinical practice, not only in patients with cancer but also in benign scenarios. Accumulated ...
Girard Olivier M OM Aix Marseille Université, CRMBM-CEMEREM UMR 7339, CNRS - AMU, Marseille, - - 2014
Recently a new MR endogenous contrast mechanism was reported. It allows specifically imaging the magnetization transfer (MT) effect arising from inhomogeneously broadened components of the NMR spectrum, and was hence dubbed ihMT. Such unique NMR lineshape properties are presumably occurring in myelin because of its specifically ordered, multilayered sheath structure. ...
Astolfo Alberto A Swiss Light Source, 5232 Villigen, PSI, Switzerland; Australian Synchrotron, Imaging and Medical Beam Line (IMBL), Clayton, Victoria, Australia. Electronic address: - - 2014
The use of alginate based microcapsules to deliver drugs and cells with a minimal host interaction is increasingly being proposed. A proficient method to track the position of the microcapsules during such therapies, particularly if they are amenable to commonly used instrumentation, would greatly help the development of such treatments. ...
Basu Sandip S From the *Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA; †Radiation Medicine Centre (BARC), Tata Memorial Centre Annexe, Parel, Bombay, Maharashtra, India; ‡Department of Radiology, University Medical Center Utrecht, Utrecht, Utrecht, the Netherlands; §Department of Orthopedic Surgery, Penn Presbyterian Medical Center, Philadelphia, PA; ¶Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, PA; and ∥Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, Delhi, - - 2014
This study aims to assess and compare the value of FDG PET with combined In-labeled leukocyte/Tc-sulfur colloid bone marrow (WBC/BM) imaging for diagnosing infection in hip and knee prostheses. In this prospective study, patients with painful hip or knee arthroplasty, who were scheduled to undergo clinical and diagnostic evaluation for ...
Thill Marc M Department of Gynecology and Obstetrics, Breast Center, AGAPLESION Markus Hospital, Frankfurt am Main, - - 2014
A positive margin in breast conserving surgery is associated with an increased risk of local recurrence. Failure to achieve clear margins results in re-excision procedures. Methods for intraoperative assessment of margins have been developed, such as frozen section analysis, touch preparation cytology, near-infrared fluorescence optical imaging, x-ray diffraction technology, high-frequency ...
Batchelor Luke J LJ Institut de Chimie Moléculaire et des Matériaux d'Orsay, Université Paris-Sud, 91405 Orsay Cedex, France. - - 2014
A dysprosium(iii) complex, exhibiting slow relaxation of magnetization, was prepared. Crystallographic studies showed a perturbation of local symmetry upon deprotonation of the ligand, with concomitant faster relaxation of magnetization. This was attributed to a large shift in the direction of the main magnetic axis, as indicated by ab initio calculations.
Treglia Giorgio G Department of Nuclear Medicine and PET/CT Center, Oncology Institute of Southern Switzerland, Bellinzona, - - 2014
The aim of the study was to meta-analyze published data about prevalence and malignancy risk of focal colorectal incidentalomas (FCIs) detected by Fluorine-18-Fluorodeoxyglucose positron emission tomography or positron emission tomography/computed tomography ((18)F-FDG-PET or PET/CT). A comprehensive computer literature search of studies published through July 31(st) 2012 regarding FCIs detected by ...
Leinonen Ville - - 2014
PET imaging of amyloid-beta (Abeta) in vivo holds promise for aiding in earlier diagnosis and intervention in Alzheimer's disease (AD) and mild cognitive impairment. AD-like Abeta pathology is a common comorbidity in patients with idiopathic normal pressure hydrocephalus (iNPH). Fifty patients with iNPH needing ventriculo-peritoneal shunting or intracranial pressure monitoring ...
Liu Xin X From the Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology of Chinese Academy of Sciences, Shenzhen Key Laboratory for MRI, 1068 Xueyuan Ave, Shenzhen, Guangdong 518055, China (X.L., N.Z., H.Z.); Beijing Center for Mathematical and Information Disciplinary Sciences, Beijing, China (X.L., H.Z.); Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, Calif (Z.F., D.L.); Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China (Q.Y.); and Department of Radiology, Peking University Shenzhen Hospital, Shenzhen, China (F.F., - - 2014
Purpose To assess image quality and diagnostic performance of unenhanced magnetic resonance (MR) angiography with use of flow-sensitive dephasing (FSD)-prepared steady-state free precession (SSFP) of the foot arteries in patients with diabetes. Materials and Methods This prospective study was approved by institutional review board. Informed consent was obtained from all ...
Stefano A A Institute for Molecular Bioimaging and Physiology (IBFM), National Research Council (CNR) Cefalù‑Segrate, Cefalù, Palermo, Italy - - - 2014
The aim of this work is to evaluate the metabolic impact of Partial Volume Correction (PVC) on the measurement of the Standard Uptake Value (SUV) from [18F]FDG PET-CT oncological studies for treatment monitoring purpose. Twenty-nine breast cancer patients with bone lesions (42 lesions in total) underwent [18F]FDG PET-CT studies after ...
Abellán Gonzalo G Instituto de Ciencia Molecular, Univ. de Valencia, Catedrático José Beltrán 2, 46980, Paterna, Valencia, - - 2014
A magnetic photoresponsive hybrid material is prepared by intercalation of a switchable trans-azobenzene-4,4'-dicarboxylate guest in the interlamellar space offered by a ferromagnetic Co(2+) Al(3+) -layered double hydroxide (LDH) host. Magnetic switching is triggered by compression/modification of the in-plane structure coupled the guest's isomerization causing a change in the magnetization of ...
Grant Frederick D FD Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA; Joint Program in Nuclear Medicine, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Electronic address: - - 2014
(18)F-FDG PET and PET/CT have a wide variety of indications in children and young adults. Oncologic indications are the most common, but others include neurology, sports medicine, cardiology, and infection imaging. Accurate interpretation of pediatric (18)F-FDG PET and PET/CT requires a technically adequate study and knowledgeable interpretation of the images. ...
Højgaard Liselotte L Department of Clinical Physiology, Nuclear Medicine & PET, Faculty of Health and Medical Sciences, Rigshospitalet, University of Copenhagen, KF 4011, Blegdamsvej 9, DK 2100, Copenhagen, Denmark. Electronic address: - - 2014
Positron emission tomography (PET)/computed tomography with FDG of the head and neck region is mainly used for the diagnosis of head and neck cancer, for staging, treatment evaluation, relapse, and planning of surgery and radio therapy. This article is a practical guide of imaging techniques, including a detailed protocol for ...
Pottier Géraldine - - 2014
Rheumatoid arthritis (RA) is a chronic disease, affecting 0.5-1% of adults in industrialized countries, in which systemic inflammation and synovitis drive joint destruction. [18F]DPA-714 is a specific tracer of the 18 kDa Translocator Protein (TSPO), which is overexpressed on activated macrophages, and proposed as a biomarker of neuroinflammation. Today, diagnosis ...
Brennan Sandra B SB Breast Imaging Section, Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY. Electronic address: - - 2014
Magnetic resonance Imaging-guided breast biopsy is an essential component of breast imaging practices offering breast magnetic resonance imaging. Careful planning and preparation allow for an efficient and successful biopsy. Deliberate positioning and controlled compression are keys to a comfortable and cooperative patient. The biopsy is only complete once imaging-histologic correlation ...
de Lartigue J J Jane de Lartigue Scientific Communications, Camberley, UK. - - 2014
Alzheimer's disease (AD) is a progressive, neurodegenerative disease likely to dramatically increase in prevalence in the next few decades. Currently, the only method for definitive diagnosis is to determine the presence of β-amyloid in the brain of AD patients at autopsy. Flutemetamol (18F) (Vizamyl™) is a novel (18)F-labeled radiotracer for ...
Ida Masahiro M Department of Radiology, Tokyo Metropolitan Ebara Hospital, Tokyo, - - 2014
To compare the lesion contrast and signal to noise ratio (SNR) obtained with T1-weighted pointwise encoding time reduction with radial acquisition (PETRA) to those of Magnetization-Prepared RApid Gradient-Echo (MPRAGE) for contrast-enhanced imaging of primary and metastatic intracranial tumors, and to investigate whether PETRA is able to reduce acoustic noise for ...
Rotstein Benjamin H BH Division of Nuclear Medicine and Molecular Imaging & Center for Advanced Medical Imaging Sciences, Massachusetts General Hospital , Boston, Massachusetts 02114, United States ; Department of Radiology, Harvard Medical School , Boston, Massachusetts 02114, United - - 2014
Bexarotene (Targretin) is a retinoid X receptor (RXR) agonist that has applications for treatment of T cell lymphoma and proposed mechanisms of action in Alzheimer's disease that have been the subject of recent controversy. Carbon-11 labeled bexarotene ([(11)C-carbonyl]4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid) was synthesized using a Cu-mediated cross-coupling reaction employing an arylboronate precursor ...
Weiler-Sagie Michal M Nuclear Medicine Department, Rambam Health Care Campus, Haifa, Israel, - - 2014
Fluoro-deoxyglucose positron emmission tomography combined with computed tomography (FDG-PET/CT) is superior to iliac bone marrow biopsy (iBMB) for detection of bone marrow involvement (BMI) in staging of Hodgkin's lymphoma (HL). The present study aims to characterize the patterns and distribution of BMI in HL as determined by FDG-PET/CT. Reports of ...
Benveniste Ana P AP Department of Diagnostic Radiology,The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: - - 2014
(18)F-fluorodeoxyglucose positron emission computed tomography (FDG PET-CT) is widely used in the initial staging and response evaluation of patients with malignancy. This review describes a spectrum of benign breast findings incidentally detected by FDG PET-CT at staging that may be misinterpreted as malignancy. We describe the pattern of distribution and ...
Jones Robert P RP From the *Department of Radiology, Stanford University Medical Center, and †Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, Stanford University Medical Center, Stanford, - - 2014
A 57-year-old male patient with a history of metastatic melanoma and sclerotic bone lesions seen on CT was referred for F NaF PET/CT evaluation of active skeletal metastases. While the bone lesions had no uptake and were therefore thought to represent sequela of previously treated disease, an unexpected area of ...
Saranathan Manojkumar M From the Departments of *Radiology, †Electrical Engineering, and ‡Neurology and Neurological Sciences, Stanford University, Stanford, - - 2014
The aim of this study was to optimize the 3-dimensional (3D) fluid attenuated inversion recovery (FLAIR) pulse sequence for isotropic high-spatial-resolution imaging of white matter (WM) and cortical lesions at 7 T. We added a magnetization-prepared (MP) FLAIR module to a Cube 3D fast spin echo sequence and optimized the ...
Kitajima Kazuhiro K Department of Radiology and of Obstetrics and Gynecology of Kobe University Graduate School of Medicine, Kobe, Japan. Electronic address: - - 2014
To investigate the fusion of pelvic magnetic resonance imaging (MRI) and fluorodeoxyglucose positron emission tomography (PET) for assessment of locoregional extension and nodal staging of cervical cancer. PET/computed tomography (CT), MRI, and non-fused and fusion of PET and MRI for assessing the extent of the primary tumor and metastasis to ...
Surasi Devaki Shilpa DS Division of Molecular Imaging and Therapeutics, Department of Radiology, University of Alabama at Birmingham, Birmingham, - - 2014
For many types of cancer, (18)F-FDG PET/CT is commonly used in evaluation and management, including tumor diagnosis, staging, restaging, treatment monitoring, and radiation therapy planning. Meticulous patient preparation including restrictions of diet and activity and management of blood glucose levels in diabetic patients, as well as an awareness of the ...
Heusch Philipp P University Dusseldorf, Medical Faculty, Department of Diagnostic and Interventional Radiology, Dusseldorf, - - 2014
Therapeutic decisions in non-small cell lung cancer (NSCLC) patients depend on the tumor stage. PET/CT with (18)F-FDG is widely accepted as the diagnostic standard of care. The purpose of this study was to compare a dedicated pulmonary (18)F-FDG PET/MR imaging protocol with (18)F-FDG PET/CT for primary and locoregional lymph node ...
Ota Naotoshi - - 2014
We compared the efficacies of ¹⁸F-fluoride positron emission tomography (¹⁸F-fluoride PET)/CT, ¹⁸F-fludeoxyglucose PET (¹⁸F-FDG PET)/CT, and ⁹⁹mTc bone scintigraphy [planar and single photon emission CT (SPECT)] for the detection of bone metastases in patients with differentiated thyroid carcinoma (DTC). We examined 11 patients (8 females and 3 males; mean age ...
Murakami Koji K Division of Nuclear Medicine, Department of Diagnostic Radiology, School of Medicine, Keio University, 35 Shinanomachi, Shinjyuku-ku, Tokyo, 160-8582, Japan. - - 2014
Recent advancement in computed tomography (CT) enables us to obtain high spatial resolution image and made it possible to construct extensive high-definition three-dimensional (3D) images. But a lack of contrast resolution in CT alone is still remained problem. Meanwhile, as fluorodeoxyglucose-positron emission tomography (PET) can visualize tumors in high contrast, ...
Hodolic Marina M Department for nuclear medicine, University Medical Centre, Ljubljana, - - 2014
Fluorocholine(18F) (FCH) was introduced at the beginning of April 2010 in France, Slovenia and three other EU member states for the localisation of bone metastases of prostate cancer with PET. The aim of the study was to compare the evolution of diagnostic imaging in patients with prostate cancer using a ...
Lodder W L WL Department of Head and Neck Oncology and Surgery, Netherlands Cancer Institute - Antoni van Leeuwenhoek, Amsterdam, The - - 2014
Aim: Preoperative detection of extranodal spread (ENS) in head and neck cancer can have important consequences for patient management. The aim of this study was to determine whether 18-fluorodeoxyglucose positron emission tomography ([18F]FDG PET) or a combination with Magnetic Resonance Imaging (MRI) could more accurately predict ENS, especially with the ...
Shah N Jon NJ Institute of Neuroscience and Medicine, INM-4: Medical Imaging Physics, Forschungszentrum Jülich GmbH, Jülich, Germany; Department of Neurology, Faculty of Medicine, JARA, RWTH Aachen University, Aachen, - - 2014
Simultaneous, hybrid MR-PET is expected to improve PET image resolution in the plane perpendicular to the static magnetic field of the scanner. Previous papers have reported this either by simulation or experiment with simple sources and detector arrangements. Here, we extend those studies using a realistic brain phantom in a ...
Annunziata Salvatore S Institute of Nuclear Medicine, Catholic University of the Sacred Heart, Largo Agostino Gemelli 8, 00168 Rome, - - 2014
Objective. To meta-analyze published data about the diagnostic accuracy of fluorine-18-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET) or PET/computed tomography (PET/CT) for primary tumor evaluation in patients with cholangiocarcinoma (CCa). Methods. A comprehensive literature search of studies published through December 31, 2013, was performed. Pooled sensitivity and specificity were calculated on ...
Ye Hu H Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of - - 2014
Head movement during a dynamic brain PET/CT imaging results in mismatch between CT and dynamic PET images. It can cause artifacts in CT-based attenuation corrected PET images, thus affecting both the qualitative and quantitative aspects of the dynamic PET images and the derived parametric images. In this study, we developed ...
Agulla Jesús J Department of Neurology, Neurovascular Area, Clinical Neurosciences Research Laboratory, Hospital Clínico Universitario, Health Research Institute of Santiago de Compostela (IDIS), University of Santiago de Compostela, E-15706 Santiago de Compostela, Spain.; Research Unit, University Hospital of Salamanca and Institute of Health Sciences of Castilla and Leon, E-37007 Salamanca, - - 2013
In order to provide sufficient sensibility for detection, selection of an adequate payload of imaging probe is critical, during the design of MRI theranostic nanoplatforms. This fact is particularly crucial for in vivo applications in the brain, where delivery of macromolecules is limited by the blood-brain barrier. Here we report ...
Lee Soo Jin SJ Department of Nuclear Medicine, Seoul National University Hospital, 28 Yeongun-dong, Jongro-gu, Seoul, 110-744 - - 2014
The new modality of an integrated positron emission tomography/magnetic resonance imaging (PET/MRI) has recently been introduced but not validated. Our objective was to evaluate clinical performance of (18)F-fluoro-2-deoxyglucose ((18)F-FDG) PET/MRI in patients with head and neck cancer. This retrospective study was conducted between January 2013 and February 2013. Ten patients ...
Zheng Jia-He - - 2013
Radiofrequency ablation (RFA), an effective, locally directed therapy for unresectable liver metastases, can improve the survival of patients. As a functional imaging approach, F-fluorodeoxyglucose positron emission tomography (F-FDG PET) or PET-computed tomography (PET-CT) may play a crucial role in the follow-up after RFA. Our objective was to evaluate the diagnostic ...
Rahim Sania S Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: - - 2013
Positron emission mammography (PEM) has better spatial resolution than positron emission tomography/computed tomography (PET/CT), or PET/CT. We evaluated the feasibility of extremity imaging with PEM using PET as a standard. Fourteen patients underwent sequential PET/CT and PEM. PEM visualized with equal or improved resolution all of the lesions identified on ...
Nguyen Christopher - - 2013
The aim of this study was to implement and optimize a novel application of diffusion-prepared balanced steady-state free precession (bSSFP) to perform in vivo cardiac diffusion-weighted MRI. Diffusion-prepared sequences have the flexibility to diffusion encode with a multi-shot image readout. The diffusion preparation was optimized to reduce sensitivity to cardiac ...
Chen Jun - - 2013
Monodispersed Bi2S3-QD@SiO2-PEG nanoparticles are prepared by a one-pot method in a reverse microemulsion system, which exhibited remarkable performances in CT and fluorescence imaging in vitro and in vivo.
Naswa Niraj - - 2013
This study aimed to compare the diagnostic performance of Ga-DOTANOC PET/CT with F-FDG PET/CT in the patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs). Data of 51 patients with definite histological diagnosis of GEP-NET who underwent both Ga-DOTA-NOC PET-CT and F-FDG PET-CT within a span of 15 days were selected for this ...
Aksoy Sabire Yılmaz - - 2013
The demand for arthroplasty is rapidly growing as a result of the ageing of the population. Although complications such as heterotrophic ossification, fracture and dislocation are relatively rare, differentiating aseptic loosening, the most common complication of arthroplasty from infection, is a major challenge for clinicians. Radionuclide imaging is currently the ...
Viswanathan Chitra - - 2013
The role of Positron Emission Tomography/Computed Tomography (PET/CT) in the evaluation of various gynecologic malignancies in light of current available data is presented and illustrated with imaging examples, pearls, and common pitfalls. 18F-fluorodeoxyglucose PET/CT is being increasingly used in management of gynecologic malignancy and has useful applications in cervical, ovarian, ...
Li Jinxing - - 2013
We demonstrate a template electrosynthesis for large-scale low-cost preparation of remarkably small magnetically driven tailored-made helical nanoswimmers that display efficient propulsion behavior and hold considerable promise for future miniature devices in the human body.
Qiu Lin - - 2013
Pediatric lymphomas (PL) are the third most common malignancy and account for 10% to 15% of all cancers in the pediatric age group. Accurate classification and staging are important for appropriate prognosis and treatment of pediatric Hodgkin's lymphoma (PHL) and non-Hodgkin's lymphomas (PNHL) and impact patient prognosis significantly. The role ...
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