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Diehl-Schmid Janine J Department of Psychiatry and Psychotherapy, Technische Universität München, München, - - 2014
The term frontotemporal lobar degeneration (FTLD) refers to a group of neurodegenerative disorders that target the frontal and temporal lobes. It accounts for approximately 10 % of pathologically confirmed dementias but has been demonstrated to be as prevalent as Alzheimer's disease in patients below the age of 65. The 3 major ...
Chen Bo B Department of Neurology, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, P.R. - - 2014
Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis, a recently defined and frequently misdiagnosed disease characterized by psychiatric symptoms, seizures, movement disorders and autonomic dysfunction, has been observed predominantly in young females with ovarian teratoma. Conventional imaging techniques, including computed tomography (CT) and magnetic resonance imaging (MRI), are often ineffective for diagnosis of the ...
Giannantoni Nadia Mariagrazia NM Institute of Neurology, Catholic University, Rome, - - 2014
Neurofibromatosis type 1 (NF1) is a heterogeneous, common, neurocutaneous disorder presenting different complications during a life span, including cerebrovascular dysplasia. To our knowledge this is the first reported case of NF1 associated with vertebrobasilar dolichoectasia and pontine ischemic stroke. We describe a 57-year-old man with NF1 who presented an acute ...
de Flores Robin R INSERM, U1077, Caen, France; Université de Caen Basse-Normandie, UMR-S1077, Caen, France; Ecole Pratique des Hautes Etudes, UMR-S1077, Caen, France; CHU de Caen, U1077, Caen, - - 2014
Growing interest has developed in hippocampal subfield volumetry over the past few years and an increasing number of studies use the automatic segmentation algorithm implemented in FreeSurfer. However, this approach has not been validated on standard resolution T1-weighted magnetic resonance (MR) as used in most studies. We aimed at comparing ...
Bonnici K S KS Department of Acute Medicine, Chelsea & Westminster Hospital NHS Trust , London , - - 2014
Introduction. Corrosive ingestions are common, although most ingestions do not result in clinically significant effects. Limited guidance is available on the role of endoscopy and/or computerised tomography (CT) in the investigation of individuals with corrosive ingestion, and the present data regarding predictors of poor outcome are confusing. Furthermore, whilst there ...
Burgess Alison A From the Physical Sciences Platform (A.B., S.Y., O.H., N.E., K.H.) and Biological Sciences Platform (S.D., I.A.), Sunnybrook Research Institute, 2075 Bayview Ave, C713, Toronto, ON, Canada M4N 3M5; Department of Laboratory Medicine and Pathobiology (S.D., I.A.) and Department of Medical Biophysics (K.H.), University of Toronto, Toronto, Ontario, - - 2014
Purpose To validate whether repeated magnetic resonance (MR) imaging-guided focused ultrasound treatments targeted to the hippocampus, a brain structure relevant for Alzheimer disease (AD), could modulate pathologic abnormalities, plasticity, and behavior in a mouse model. Materials and Methods All animal procedures were approved by the Animal Care Committee and are ...
Ishida Atsushi - - 2014
Vasospasm is the most common cause of complication after a subarachnoid hemorrhage and tremendous efforts have been made to prevent it. A subarachnoid clot is the cause of the vasospasm and dissolving and washing it out is considered to be the best practice. Cisternal irrigation with urokinase and ascorbic acid ...
Tepmongkol Supatporn S Division of Nuclear Medicine, Department of Radiology, Faculty of Medicine, Chulalongkorn University, Rama 4 Road, Pathumwan, Bangkok, 10330, Thailand, - - 2014
Extratemporal lobe epilepsy is difficult to localize. We aimed to define the best parameter(s) of SPECT for confirmation of seizure origin among the region of maximum cerebral perfusion in ictal phase (MP), maximum change of cerebral perfusion from interictal to ictal phase (MC), and maximum extent of hyperperfusion in ictal ...
Zou Jian-Xun JX Department of Radiology, Lishui People's Hospital, Lishui 323000, PR China. Electronic address: - - 2014
The purpose of this study was to investigate the changes in the cerebral blood flow (CBF) and spectrum variables in the posterior cingulate region of patients with AD under the detection of arterial spin labeling (ASL) and magnetic resonance spectroscopy (MRS). A total of 20 AD patients (8 males and ...
Imabayashi Etsuko E Integrative Brain Imaging Center, National Center of Neurology and Psychiatry, Tokyo, 187-8551, Japan, - - 2014
Statistical analysis in neuroimaging (referred to as "neurostatistical imaging") is important in clinical neurology. Here, neurostatistical imaging and its superiority for diagnosing dementia are reviewed. In neurodegenerative dementia, the proportional distribution of brain perfusion, metabolism, or atrophy is important for understanding the symptoms and status of patients and for identifying ...
Vuorinen Miika M Department of Neurology, School of Medicine, University of Eastern Finland, Kuopio, - - 2014
Background: CAIDE Dementia Risk Score is a validated tool for estimating 20-year dementia risk in the general population based on a midlife risk profile. Objective: To investigate the associations between CAIDE score and dementia-related brain changes up to 30 years later on magnetic resonance imaging (MRI). Methods: Participants in the ...
Thordardottir Steinunn S Karolinska Institutet, Department NVS, Division of Neurogeriatrics, Center for Alzheimer Disease Research, Huddinge, Sweden Department of Geriatric Medicine, Karolinska University Hospital Huddinge, Stockholm, - - 2014
Background: It is currently believed that therapeutic interventions will be most effective when introduced at the preclinical stage of Alzheimer's disease (AD). This underlines the importance of biomarkers to detect AD pathology in vivo before clinical disease onset. Objective: To examine the evolution of cerebrospinal fluid (CSF) biomarker and brain ...
Broski Stephen M SM From the Departments of Radiology (S.M.B., C.H.H., G.B.J., V.J.L., P.J.P.), Immunology (G.B.J.), and Medical Illustration (R.F.M.), Mayo Clinic, 200 First St SW, Rochester, MN - - 2014
Movement disorders with parkinsonian features are common, and in recent years imaging has assumed a greater role in diagnosis and management. Thus, it is important that radiologists become familiar with the most common imaging patterns of parkinsonism, especially given the significant clinical overlap and diagnostic difficulty associated with these disorders. ...
Rodkong A A Department of Radiological Technology, Faculty of Associated Medical Sciences, Chiang Mai University, - - 2014
Reduction of cortical thickness and Hippocampal volume (HV) in Methamphetamine abusers (MA) has been reported. However, change of white matter volume (WMV) in MA group is inconclusive. We aim to compare cortical thickness, Hippocampal volume (HV), and WMV per intra-cranial volume (ICV) among MA in Thai adolescents. 3D T1-wighted high ...
Ni Jun J J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA The Department of Neurology, Peking Union Medical College Hospital, Peking, - - 2014
The extent of cortical involvement of cerebral amyloid angiopathy (CAA)-related microbleeds (CMBs) remains unclear. We examined five consecutive patients with probable CAA and three non-demented elderly subjects with ultra-high-field 7T MRI, to identify the precise location of CAA-related CMBs. In five CAA patients, 169 of a total of 170 lobar ...
Aylward Elizabeth H EH Seattle Children's Research Institute, Seattle, Washington, - - 2014
An abundance of research shows that magnetic resonance imaging (MRI) striatal volumes decrease long before diagnosis of Huntington's disease (HD) and closely track disease progression. Additional research indicates that these volumetric measures meet important criteria for a biomarker that can be used in clinical trials: They are 1) objectively measureable; ...
De Cocker Laurens J L LJ Department of Radiology, University Medical Center Utrecht, Utrecht, The - - 2014
Background: Small cerebellar cavities (≤15 mm) are often observed coincidentally in ageing subjects and have also been associated with migraine. Although generally assumed to be of ischaemic origin, descriptive imaging studies are sparse and imaging findings have not been correlated with histopathology. We aimed to investigate whether small ischaemic cavities ...
Erdener Sefik Evren SE Department of Neurology, School of Medicine, Hacettepe University, Ankara, Turkey - - 2014
In dacrystic seizures lacrimation has previously been reported as an ictal autonomic event accompanying emotional and somatic signs. However, it has not been observed as an isolated event in autonomic seizures. We report a patient experiencing complex partial seizures characterized by lacrimation as the initial and most prominent ictal event, ...
Augustinack Jean C JC Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, - - 2014
H.M., Henry Molaison, was one of the world's most famous amnesic patients. His amnesia was caused by an experimental brain operation, bilateral medial temporal lobe resection, carried out in 1953 to relieve intractable epilepsy. He died on December 2, 2008, and that night we conducted a wide variety of in ...
Uchiyama Shigeharu S Department of Orthopaedic Surgery, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto, 390-8621, Japan, - - 2014
The clinical characteristics of wild-type transthyretin amyloid deposition among patients with carpal tunnel syndrome (CTS) have not been well investigated. One-hundred and seven patients with idiopathic CTS who underwent carpal tunnel release were enrolled. They underwent physical examination of the hand, nerve-conduction study, and magnetic resonance imaging (MRI) study of ...
Thurfjell Lennart L GE Healthcare, Uppsala, Sweden Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden - - 2014
Clinical trials of the PET amyloid imaging agent (18)F-flutemetamol have used visual assessment to classify PET scans as negative or positive for brain amyloid. However, quantification provides additional information about regional and global tracer uptake and may have utility for image assessment over time and across different centers. Using postmortem ...
Bocchetta Martina M LENITEM (Laboratory of Epidemiology, Neuroimaging and Telemedicine), IRCCS Istituto Centro S. Giovanni di Dio Fatebenefratelli, Brescia, Italy; Department of Molecular and Translational Medicine, University of Brescia, Brescia, - - 2014
We investigated the use of Alzheimer's disease (AD) biomarkers in European Alzheimer's Disease Consortium centers and assessed their perceived usefulness for the etiologic diagnosis of mild cognitive impairment (MCI). We surveyed availability, frequency of use, and confidence in diagnostic usefulness of markers of brain amyloidosis (amyloid positron emission tomography [PET], ...
Tubbs R Shane RS Pediatric Neurosurgery, Children's Hospital of Alabama, Birmingham, AL, USA, - - 2014
Few innovations in the method of tunneling shunt tubing for cerebrospinal fluid (CSF) shunt diversion have been made since this treatment of hydrocephalus was first developed. Therefore, this feasibility study was performed with the hope of identifying an improved technique that could potentially carry fewer complications. On 10 cadaver sides ...
Willette Auriel A AA Laboratory of Neurosciences, National Institute on Aging, Biomedical Research Center, 251 Bayview Boulevard, Baltimore, MD 21224, - - 2014
Identifying predictors of mild cognitive impairment (MCI) and Alzheimer׳s disease (AD) can lead to more accurate diagnosis and facilitate clinical trial participation. We identified 320 participants (93 cognitively normal or CN, 162 MCI, 65 AD) with baseline magnetic resonance imaging (MRI) data, cerebrospinal fluid biomarkers, and cognition data in the ...
Kawashiri Shin-Ya SY Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences , Nagasaki , - - 2014
A 43-year-old Japanese woman with adult T-cell leukemia (ATL) developed rheumatoid arthritis-like polyarthritis with dermatitis and skin erosion. Her rheumatoid factor and C-reactive protein results were positive. Musculoskeletal ultrasonography showed intra-articular and peritendinous power Doppler signal-positive synovitis. Plain magnetic resonance imaging showed synovitis of the above lesion and remarkable bone ...
Göbel K K Department of Radiology, Medical Physics, University Medical Center Freiburg, Freiburg, - - 2014
The aim of this study was to demonstrate the feasibility of a custom-made phased-array microcoil within a 400 MHz animal system for the morphological characterization of human skin tissue in correlation with histopathology. A dedicated 7-channel microcoil-based MR detector arranged in a phased-array geometry was developed to combine the advantages of ...
Koehler M J MJ Department of Dermatology, SRH Waldklinikum Gera, Gera, Germany; Department of Dermatology, University Hospital Jena, Jena, - - 2014
In vivo multiphoton tomography (MPT) of human skin has become a valuable tool for non-invasive examination of morphological and biophysical skin properties and their alterations. So far, skin changes after UVB irradiation were mainly evaluated clinically and histologically. The present study aimed at non-invasive imaging of histological changes during acute ...
Watson Rosie R Institute for Ageing and Health, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne, United Kingdom; Department of Aged Care, The Royal Melbourne Hospital, Parkville, Australia. Electronic address: - - 2014
To compare magnetic resonance imaging (MRI) patterns of cortical thinning in subjects with dementia with Lewy bodies (DLB), Alzheimer's disease (AD), and normal aging and investigate the relationship between cortical thickness and clinical measures. Study participants (31 DLB, 30 AD, and 33 healthy comparison subjects) underwent 3-Tesla T1-weighted MRI and ...
AlSharif Shaza S McGill University Health Center, Royal Victoria Hospital, 687 Pine Avenue West, Montreal, PQ, H3H 1A1, - - 2014
We report a case of 43-year-old man who presented with an enlarging, painless, palpable mass in the left breast for one year associated with surface blue discoloration of the skin. Mammogram showed a well-defined 2.3-cm mass with microcalcifications. Ultrasound revealed a well-defined, subcutaneous hypoechoic mass adherent to the skin with ...
Brickman Adam M AM Taub Institute for Research on Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA; Gertrude H. Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA; Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA. Electronic address: - - 2014
Accumulating evidence implicates small vessel cerebrovascular disease, visualized as white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging, in the pathogenesis and diagnosis of Alzheimer's disease (AD). Cross-sectional volumetric measures of WMH, particularly in the parietal lobes, are associated with increased risk of AD. In the present study, we sought ...
Chance Aaron A Division of Neurological Surgery, Departments of Pediatric Surgery and Neurosurgery, University of Texas Health Science Center at Houston, Children's Memorial Hermann Hospital, and Mischer Neuroscience Institute, 6431 Fannin Street, MSB 5.144, Houston, TX, 77030, - - 2014
Hydrocephalus is common in patients with open neural tube defects (NTDs), but association with closed NTDs has rarely been reported. We describe three patients with untreated closed NTDs who required surgery for hydrocephalus. Case 1: A full-term newborn presented with a skin-covered midline lumbar spine lipoma. Magnetic resonance imaging (MRI) ...
Iino Morio M Department of Legal Medicine (Forensic Medicine), Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan. Electronic address: - - 2014
A 9months-old infant has died of scald burn by the hot water from the fallen electric pot at home. Postmortem computed tomography (CT) scanning prior to autopsy contributed to exclude the possibilities of old and new bone fractures or hidden massive hemorrhages. This procedure helped the pathologists to avoid dissecting ...
Winters Stephen J SJ Division of Endocrinology, Metabolism and Diabetes (SJW), University of Louisville School of Medicine, Louisville, Kentucky; Department of Radiation Oncology (CS), University of Louisville School of Medicine, Louisville, Kentucky; Brain Tumor Center (TV), Norton Neuroscience Institute; and Departments of Pathology (MRN), Radiology (DCC), Norton Health Care, Louisville, - - 2014
: A 60-year-old man with Addison's disease, primary hypothyroidism and type 2 diabetes mellitus who was treated with stable doses of hydrocortisone and fludrocortisone developed increasing skin pigmentation and a bitemporal hemianopia. The plasma ACTH level was 14,464 pg/mL, and an invasive pituitary macroadenoma with suprasellar extension was found on ...
Spaccarelli Natalie N Hospital of the University of Pennsylvania, 3400 Spruce Street 4283, Philadelphia, Pennsylvania, 19104, USA. - - 2014
Primary cutaneous lymphomas (PCLs) include both cutaneous T-cell and B-cell lymphomas and comprise the second most common type of extra-nodal non-Hodgkin's lymphomas. The treatment and prognosis of PCLs typically depend on the extent of disease. In evaluating extent of disease in oncological processes, computed tomography (CT) provides a purely anatomical ...
Karunanithi Sellam S From the Departments of *Nuclear Medicine, and †Pathology, All India Institute of Medical Sciences, New Delhi, - - 2014
Dermatofibrosarcoma protuberans (DFSP) is an uncommon cutaneous soft tissue sarcoma tumor that arises from the dermis of the skin. Sarcomas of the intestines are rare, and a DFSP arising from the small intestine is a very rare occurrence. Here we present F-FDG PET/CT imaging findings of a 60-year-old man with ...
Mallinson Paul Ian PI 1 Department of Radiology, Vancouver General Hospital and University of British Columbia, 899 W 12th Ave, Vancouver, BC V5Z 1M9, - - 2014
OBJECTIVE. The objective of our study was to discover the types and incidence of artifacts in dual-energy CT (DECT) using datasets of 50 consecutive patients who underwent a four-limb DECT protocol for the evaluation of suspected gout. Identification of artifacts and techniques for artifact reduction are discussed. CONCLUSION. Artifacts commonly ...
Islam M N MN Dr Mohammad Nazrul Islam, Assistant Professor & Head, Department of Neuro Radiology & Imaging, National Institute of Neuro Sciences & Hospital, Sher-E-Bangla Nagar, Dhaka - - 2014
Imaging cerebral infarction in first few hours after the onset of clinical symptoms is a challenge. The role of stroke imaging underwent a paradigm shift from confirmation of infarction from and exclusion of hemorrhage to the detection of the tissue at risk that may be rescued with restoration of circulation. ...
Matera Giovanni G Institute of Microbiology, Department of Health Sciences, "Magna Graecia" University, Catanzaro, - - 2014
Late/chronic Lyme neuroborreliosis (LNB) represents a challenging entity whose diagnosis requires a combination of clinical and laboratory findings, surrounded by much controversy. Here we describe a patient who had a peculiar form of late LNB with CNS lesions shown by magnetic resonance imaging (MRI), and epileptic seizures, etiologically diagnosed by ...
Ilott Andrew J AJ Department of Chemistry, New York University, 100 Washington Square East, New York, NY 10003, - - 2014
While experiments on metals have been performed since the early days of NMR (and DNP), the use of bulk metal is normally avoided. Instead, often powders have been used in combination with low fields, so that skin depth effects could be neglected. Another complicating factor of acquiring NMR spectra or ...
Gerrish Amy C AC Department of Imaging, Leicester Royal Infirmary, Leicester, - - 2014
Diffusion tensor imaging is increasingly available on clinical magnetic resonance scanners and can be acquired in a relatively short time. There has been an explosion of applications in the research field but the use to the practicing radiologist may seem obscure. This paper aims to highlight how diffusion tensor imaging ...
Liu Jun J Department of Radiology, Second Xiangya Hospital, Central South University, Changsha, Hunan Province, China ; Department of Biomedical Engineering and Radiology, School of Medicine, Wayne State University, 3990 John R St, Detroit, MI, USA ; School of Public Administration, Central South University, Changsha, Hunan Province, - - 2014
Previous neuropathological studies regarding traumatic brain injury have primarily focused on changes in large structures, for example, the clinical prognosis after cerebral contusion, intracerebral hematoma, and epidural and subdural hematoma. In fact, many smaller injuries can also lead to severe neurological disorders. For example, cerebral microbleeds result in the dysfunction ...
Yang Minglei M Department of Biomedical Engineering, School of Medicine, Tsinghua University, Room C249, Beijing, 100084, People's Republic of China, - - 2014
Ultrasound-MRI/CT fusion imaging is widely used in minimal invasive surgeries, such as liver biopsy and tumor ablation. However, respiration-induced quasi-periodic liver motion and deformation cause unacceptable misalignment of the fusion images (i.e., fusion error). A subject-specific liver motion model based on skin-mounted position sensor and corresponding ultrasound liver image sequence ...
Chung Jae-Joon JJ Department of Radiology and Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 135-720, Korea, - - 2014
This study was done to investigate the efficacy of a lead shield in protecting the tissues outside the primary beams, such as the breast and thyroid, by measurement of the entrance skin dose during CT of the brain, neck, abdomen, and lumbar spine. Institutional Review Board approval was obtained. This ...
Lapa Constantin C From the Departments of *Nuclear Medicine, and †Hematology and Oncology, Universitätsklinikum Würzburg, Würzburg, - - 2014
A 63-year-old man with a 1-year course of IgA-λ multiple myeloma (MM) and a history of autologous stem cell transplantation presented with multiple nontender, nodular violaceous skin lesions that were located predominantly on his trunk. Diagnostic workup using F-FDG PET/CT revealed disseminated disease including highly hypermetabolic (sub)cutaneous lesions, consistent with ...
Jiang Zhaohua Z Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China. Electronic address: - - 2014
The surgical treatment of microcystic lymphatic malformations (LMs) has historically been difficult and frustrating because of a high recurrence rate due to incomplete resection. However, complete removal of the multifocal and extensive lesions rely on accurate imaging diagnosis and effective repair methods for the resulting large defect. The purpose of ...
Juan Yu-Hsiang YH 1 Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, L1, ASB-1, 75 Francis St, Boston, MA - - 2014
OBJECTIVE. The purpose of this article is to enlighten radiologists with the clinical presentation, multimodality imaging features, local recurrence, distant spread, differential diagnosis, and prognosis of skin and subcutaneous malignancies. CONCLUSION. Cutaneous and subcutaneous malignancies represent the most common type of cancer and frequently present with overlapping imaging appearances. CT, ...
Sasaki Makoto M Division of Clinical Radiology Service, Kyoto University - - 2014
The purpose of this study was to evaluate the accuracy of positional verification during overall radiation treatment periods in accelerated partial breast irradiation using one or more surgical clips. We first investigated the appropriate computed tomography (CT) slice thickness and detectability of clips for a matching criterion in a phantom ...
Cyrulnik Amanda A - - 2014
Multicentric reticulohistiocytosis (MR) is a rare debilitating disease that involves the skin and joints. It most commonly affects white individuals but has been reported in other ethnic groups including black individuals, Native Americans, and Asians. The Hispanic population is largely underrepresented in the epidemiology of MR. We describe 2 Hispanic ...
Santra Amburanjan A Department of Nuclear Medicine, Medical College, Kolkata, West Bengal, - - 2014
There is a growing health burden in developing countries due to recent trends of increasing incidence of neurodegenerative diseases. To reduce the healthcare cost and effective management of dementia illness, early diagnosis, accurate differentiation and their progression assessment is becoming crucially important. We are utilizing (99m)Tc-d, l-hexamethyl propyleneamine oxime (HMPAO) ...
Lin Ai-Ling AL Sanders-Brown Center on Aging, Department of Pharmacology & Nutritional Sciences, University of Kentucky, Lexington, KY, - - 2014
Brain metabolism declines with age and do so in an accelerated manner in neurodegenerative disorders. Noninvasive neuroimaging techniques have played an important role to identify the metabolic biomarkers in aging brain. Particularly, PET with fluorine-18 ((18)F)-labeled 2-fluoro-2-deoxy-d-glucose tracer and proton magnetic resonance spectroscopy (MRS) have been widely used to monitor ...
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