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Teixido Michael T MT From the *Thomas Jefferson University, Philadelphia, Pennsylvania; †Christiana Care Health Systems, Newark, Delaware; ‡Loma Linda Medical Center Loma Linda, California; §Colden & Seymour ENT and Allergy, Newburyport, Massachusetts; ‚ą•University of Delaware, Newark, Delaware; ¶Division of Otolaryngology-Head and Neck Surgery, Saad Specialist Hospital, Al-Khobar, Saudi Arabia; and #Division of Otolaryngology-Head and Neck Surgery, College of Medicine, The Pennsylvania State University, Hershey, - - 2014
In the current study, we attempted to determine normative inner ear volumetric measurements generated from three-dimensional computed tomography (CT) images. In addition, we investigated a correlation between the axial length and the volume of the labyrinth and discussed clinical outcomes of this correlation. Amira 5.2.2 software was used to create ...
Yoon Jeong Hee JH From the *Department of Radiology, Seoul National University Hospital, †Institute of Radiation Medicine, Seoul National University College of Medicine; ‡Siemens Healthcare; and §Department of Pathology, Seoul National University Hospital, Seoul, South - - 2014
The purpose of this study was to determine whether hepatic extracellular volume fractions (fECVs) measured using multiphasic liver computed tomography (CT) can be used to quantify the severity of hepatic fibrosis (HF). This retrospective study was approved by our institutional review board, and the requirement for informed consent was waived. ...
Colen Rivka R RR From the Department of Radiology, University of Texas MD Anderson Cancer Center, 1400 Pressler St, Unit 1482, Houston, TX 77030 (R.R.C., J.W., S.K.S., P.O.Z.); Department of Biomedical Informatics, Emory University, Atlanta, Ga (D.A.G.); and Department of Neurosurgery, Baylor College of Medicine, Houston, Tex - - 2014
Purpose To identify the molecular profiles of cell death as defined by necrosis volumes at magnetic resonance (MR) imaging and uncover sex-specific molecular signatures potentially driving oncogenesis and cell death in glioblastoma ( GBM glioblastoma ). Materials and Methods This retrospective study was HIPAA compliant and had institutional review board ...
Zeng Shu-Xiong SX Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai, - - 2014
Sexual curiosity and the quest for sexual excitement are the most frequent reasons for patients to introduce foreign bodies into the urethra or the bladder. Imagination and surgical skill are essential for urologists to retrieve such vesical foreign bodies. The aim of this study was to describe a novel method ...
Takahashi Teruyuki T Department of Radiology, Hiroshima Red Cross Hospital and Atomic-bomb Survivors Hospital, Hiroshima, - - 2014
Although several studies have shown the diagnostic and prognostic value of CT-based attenuation correction (AC) of single photon emission computed tomography (SPECT) images for diagnosing coronary artery disease (CAD), this issue remains a matter of debate. To clarify the characteristics of CT-AC SPECT images that might potentially improve diagnostic performance, ...
Daniels M L A ML Department of Medicine, UNC School of Medicine, Chapel Hill, NC 27599, USA. Electronic address: - - 2014
To develop and validate a simple, reproducible method to assess dural sac size using standard imaging technology. This study was institutional review board-approved. Two readers, blinded to the diagnoses, measured anterior-posterior (AP) and transverse (TR) dural sac diameter (DSD), and AP vertebral body diameter (VBD) of the lumbar vertebrae using ...
Hassler Eva Maria EM Ludwig Boltzmann Institute for Clinical Forensic Imaging, Universitätsplatz 4/II, 8010, Graz, - - 2014
In clinical forensic medicine, hematomas and other externally visible injuries build the basis for the reconstruction of events. However, dating of subcutaneous hematomas based on their external aspect is difficult. Magnetic resonance imaging (MRI) has proven its use in dating intracranial hemorrhage. Thus, the aim was to investigate if MRI ...
Long Liu Yan LY Department of Plastic and Cosmetic Surgery, Chongqing Southwest Hospital, Third Millitary Medical University, Chongqing, - - 2014
The present study was to examine the distribution of lymphatic vessels in the penis of normal adult males, which could provide an anatomical basis for improvement of incisions in penile lengthening surgery, and may also help to prevent postoperative refractory edema. Thirteen normal adult male volunteers were recruited for this ...
Kranz Georg S GS Departments of Psychiatry and Psychotherapy - - 2014
Biological causes underpinning the well known gender dimorphisms in human behavior, cognition, and emotion have received increased attention in recent years. The advent of diffusion-weighted magnetic resonance imaging has permitted the investigation of the white matter microstructure in unprecedented detail. Here, we aimed to study the potential influences of biological ...
Shirodkar Chetan G CG Department of Critical Care Medicine and Department of Radiology, Yashoda Multi-Speciality Hospital, Somajiguda, Hyderabad, Telangana, - - 2014
The aim was to evaluate efficacy of optic nerve sheath diameter (ONSD) by ultrasound as a noninvasive method for detecting raised intracranial pressure (ICP) in intensive care unit, to compare with computed tomography/magnetic resonance imaging (MRI) findings of raised ICP and to prognosticate ONSD value with treatment. We conducted a ...
Gufler Hubert H Department of Diagnostic Radiology, Martin-Luther-University Halle-Wittenberg, 06120 Halle (Saale), - - 2014
Knowledge of cranial suture morphology is crucial in emergency medicine, forensic medicine, and maxillofacial reconstructive surgery. This study assessed the visibility of sutures of the orbit and periorbital region on multidetector computed tomography. Multidetector computed tomography scans of 200 patients (127 males, 73 females; mean age 51.3 years; range, 6-92 ...
Tan Winson Jianhong WJ Department of General Surgery, Singapore General Hospital, Singapore. Electronic address: - - 2014
Although computed tomography (CT) has reduced negative appendectomy rates, its radiation risk remains a concern. We compared the performance statistics of the Alvarado Score (AS) with those of CT scan in the evaluation of suspected appendicitis, with the aim of identifying a subset of patients who will benefit from CT ...
Park Moon Soo MS Department of Orthopaedic Surgery, Medical College of Hallym University, 896, Pyeongchon-dong, Dongan-gu, Anyang-si, Gyeonggi-do, 431-070, Republic of Korea. Electronic address: - - 2014
The benefits of oblique magnetic resonance imaging (MRI) reformations to assess cervical neural foramina have been reported previously in clinical and cadaveric studies. But there is a paucity of literature investigating intra- and interobserver variabilities for assessing cervical foraminal stenosis using oblique MRI views. To determine the value of oblique ...
Fidalgo L E LE Departamento de Ciencias Clínicas Veterinarias, Universidad de Santiago de Compostela, Lugo, - - 2014
This study was conducted to assess the reliability of computed tomography (CT) for diagnosing bot fly infestations by Cephenemyia stimulator (Clark) (Diptera: Oestridae) in roe deer (Capreolus capreolus L.) (Artiodactyla: Cervidae). For this purpose, the heads of 30 animals were analysed, firstly by CT and then by necropsy, which was ...
Guo Yu-Jiao YJ Department of Oral and Maxillofacial Radiology, Peking University School and Hospital of - - 2014
An otherwise healthy 14-year-old male was referred to our hospital for the evaluation of a mass which was noticed two months ago. The mass located in the left submandibular area. Comprehensive imaging examinations including panoramic radiography, computed tomography (CT) and positron emission tomography- computed tomography (PET-CT) were performed. Appropriate surgical ...
Hua Wei W Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, Shanghai 200063, P.R. China; East China University of Political Science and Law, Shanghai 200042, - - 2014
The aim of this study was to evaluate the correlation between age and the parameters of medial epiphysis of clavicle based on CT volume rendering (VR) images. The CT images of the medial clavicle from 795 teenagers (387 male and 408 female) between 15 and 25 years were collected in ...
Takatsu Yasuo Y Department of Radiology, Osaka Red Cross Hospital, Osaka, Japan Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan - - 2014
Relaxation time of female reproductive organs affects the tissue contrast of magnetic resonance image (MRI), and is used for quantitative analysis. To evaluate the relaxation times of normal female reproductive organs in the luteal phase of the menstrual cycle. On a 1.5-T MRI, relaxation times were measured in pelvic tissues ...
Mondelli Mauro M EMG Service, Health District no.7, Siena, - - 2014
Objective Some anthropometric measures were reported in association with carpal tunnel syndrome (CTS). Our aim was to detect optimal cut-offs of body, hand/wrist measures to correctly identify CTS patients using receiver-operating characteristic (ROC) curves. Methods We enrolled one CTS case for two controls regardless of age and gender. CTS diagnosis ...
Mabry Christian C Louisiana State University Health Sciences Center in New - - 2014
A 61-year-old male with a past medical history of chronic, uncontrolled hypertension received a non-contrasted computed tomogram (CT) of the chest and abdomen to investigate for possible Conn syndrome. This noncontrast study showed some areas of nodularity around the vertebral bodies bilaterally and extending into the posterior mediastinal region. A ...
Liu Weiming W Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Tiantan Xili 6, 100050 Beijing, - - 2014
To describe an association of growth hormone (GH) secreting pituitary microadenomas and empty sella (ES), which has been described in case reports - the underlying mechanisms are unclear. We retrospectively analyzed patients operated for GH-producing pituitary adenomas between February 2004 and February 2009. Magnetic resonance imaging (MRI), computed tomography (CT) ...
Vaitkus Paul T PT Cardiology Division (Mail Stop 111D), Bay Pines VA Medical Center, PO Box 5005, 10000 Bay Pines Blvd, Bay Pines, FL 33744 USA. - - 2014
Transcatheter aortic valve replacement (TAVR) can be complicated by significant paravalvular leak (PVL). Optimal selection of TAVR prosthesis size can minimize the risk of clinically significant PVL. The aim of this study was to assess the utility of a proprietary software package, HeartNavigator (Philips), in selecting TAVR prosthesis to minimize ...
van Gool Matthijs H MH Department of Surgical Oncology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The - - 2014
To prospectively evaluate diagnostic computed tomography (CT) and (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) for identification of histopathologic response to neoadjuvant erlotinib, an epidermal growth factor receptor-tyrosine kinase inhibitor in patients with resectable non-small cell lung cancer (NSCLC). This study was designed as an open-label phase 2 trial, performed in ...
Frellesen Claudia C Department of Diagnostic and Interventional Radiology, Clinic of the Goethe University, Theodor-Stern-Kai 7, 60590, Frankfurt, - - 2014
To investigate the impact of automated attenuation-based tube potential selection on image quality and exposure parameters in polytrauma patients undergoing contrast-enhanced thoraco-abdominal CT. One hundred patients were examined on a 16-slice device at 120 kV with 190 ref.mAs and automated mA modulation only. Another 100 patients underwent 128-slice CT with automated ...
Parekh Parth J PJ Eastern Virginia Medical School, Department of Internal Medicine , Norfolk, VA , - - 2014
Introduction: The prevalence of gastroesophageal reflux disease continues to increase with the aging population and the obesity epidemic. Therapeutic failures can have significant detrimental effects in patients. Recently, dexlansoprazole MR and esomeprazole strontium were introduced to the class of proton pump inhibitors (PPIs). Areas covered: This article will review the ...
Prabhakaran S S From the Departments of Neurology (S.P., R.A.B.) and Radiology (M.S., A.R.H., A.S., M.C.H., S.A.A.), Northwestern University, Chicago, Illinois; and Department of Neurology (V.H.L., J.J.C.), Rush University Medical Center, Chicago, Illinois; and Department of Economics and Decision Sciences (F.D.-V.), Western Illinois University, Macomb, - - 2014
Controversy exists about the role of perfusion imaging in patient selection for endovascular reperfusion therapy in acute ischemic stroke. We hypothesized that perfusion imaging versus noncontrast CT- based selection would be associated with improved functional outcomes at 3 months. We reviewed consecutive patients with anterior circulation strokes treated with endovascular ...
Thomeer Maarten G MG Department of Radiology, Erasmus Medical Center, Rotterdam, The - - 2014
Hepatocellular adenoma (HCA) is a generally benign liver tumor with the potential for malignancy and bleeding. HCAs are categorized into four subtypes on the basis of genetic and pathological features: hepatocyte nuclear factor 1α-mutated HCA, β-catenin-mutated HCA, inflammatory HCA, and unclassified HCA. Magnetic resonance imaging (MRI) plays an important role ...
Hegazy Abdelmonem A AA Anatomy Department, Faculty of Medicine, Zagazig University, Zagazig 44519, - - 2014
Despite the increasing recognition of the functional and clinical importance of lumbar lordosis, little is known about its description, particularly in Egypt. At the same time, magnetic resonance imaging (MRI) has been introduced as a noninvasive diagnostic technique. The aim of this study was to investigate the anatomy of the ...
Eslami Sohrab S Laboratory for Computational Sensing and Robotics (LCSR) at the Johns Hopkins University, Baltimore, MD, - - 2013
This paper undertakes the modular design and development of a minimally invasive surgical manipulator for MRI-guided transperineal prostate interventions. Severe constraints for the MRI-compatibility to hold the minimum artifact on the image quality and dimensions restraint of the bore scanner shadow the design procedure. Regarding the constructive design, the manipulator ...
Van Vugt Raoul R Department of Surgery and Trauma, Radboud University Nijmegen Medical Center, PO Box 9101, Nijmegen, Netherlands, 6500 - - 2013
Trauma is the fifth leading cause of death worldwide, and in people younger than 40 years of age, it is the leading cause of death. During the resuscitation of trauma patients at the emergency department, there are two different commonly used diagnostic strategies. Conventionally, there is the use of physical ...
Wiegerinck E M A - - 2013
The choice of preferred access route for transcatheter aortic valve implantation (TAVI) is mainly guided by the minimal aorto-femoral tract diameter. Currently, projection angiography (XA) and CT-angiography (CTA) are used interchangeably to assess this diameter in the TAVI work-up. We aimed to assess the agreement of XA and CTA diameter ...
Truong Hong H National Institutes of Health, Bethesda, Maryland, - - 2013
Prior studies of volumetric effects of 5α-reductase inhibitors (5ARIs) on the prostate have used transrectal ultrasound which provides poor differentiation of prostatic zones. We utilized high-resolution prostate MRI to evaluate the true dynamic effects of 5ARI in men who underwent multiple MRIs. A retrospective study of patients who underwent serial ...
Learned K O - - 2013
BACKGROUND AND PURPOSE:Absorbable gelatin-thrombin matrix is increasingly being used in neurosurgical procedures; unlike other hemostats, the stable matrix is left undisturbed and fills the surgical bed after achieving hemostasis. We investigated the immediate postoperative radiographic imaging appearance of the gelatin-thrombin matrix in intracranial operative beds.MATERIALS AND METHODS:Thirty-one consecutive patients (18 ...
Lartizien Carole - - 2013
We have designed a computer aided diagnosis system to discriminate between hypermetabolic cancer lesions and hypermetabolic inflammatory or physiological but noncancerous processes in FDG PET/CT exams of lymphoma patients. Detection performance of the support vector machine (SVM) classifier was assessed based on feature sets including 105 PET and CT characteristics ...
Beloueche-Babari M M Cancer Research UK and EPSRC Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Sutton, Surrey SM2 5PT, - - 2013
Non-invasive imaging biomarkers underpin the development of molecularly targeted anti-cancer drugs. This study evaluates tumour apparent diffusion coefficient (ADC), measured by diffusion-weighted magnetic resonance imaging (DW-MRI), as a biomarker of response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) in human tumour xenografts. Nude mice bearing human BRAF(V600D) WM266.4 melanoma or ...
Yamano Shigeru - - 2013
Patients with a history of ischemic stroke are known to develop new ischemic stroke. While asymptomatic, the presence and progression of silent brain infarcts and white matter lesions on magnetic resonance imaging are associated with an increased risk of future strokes. Both angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers ...
Niemann Tilo - - 2013
To evaluate the clinical impact of automatic tube voltage selection on chest CT angiography (CTA). Ninety-three patients were prospectively evaluated with a CT protocol aimed at comparing two successive CTAs acquired under similar technical conditions except for the kV selection: (1) the initial CTA was systematically obtained at 120 kVp and ...
Sampath Deepak - - 2013
The phosphatidylinositol 3-kinase (PI3K) pathway is a central mediator of vascular endothelial growth factor (VEGF)-driven angiogenesis. The discovery of small molecule inhibitors that selectively target PI3K or PI3K and mammalian target of rapamycin (mTOR) provides an opportunity to pharmacologically determine the contribution of these key signaling nodes in VEGF-A-driven tumor ...
Betz Martina - - 2013
Solely size-based response criteria may be unreliable in patients with gastrointestinal stromal tumors (GIST) treated with tyrosine kinase inhibitors, because they typically underestimate responses to treatment. As GISTs are generally hypervascularized and novel targeted drugs knowingly affect angiogenic signaling pathways, perfusion measurements are expected to deliver important information about their ...
Kaste Sue C - - 2013
PURPOSE: To evaluate the growing skeleton for potential altered skeletalgenesis associated with antiangiogenesis therapy. PATIENTS AND METHODS: Knee radiographs and magnetic resonance imaging (MRI) were prospectively obtained on patients enrolled on two consecutive clinical trials using vandetanib, a potent oral (VEGF receptor 2) VEGFR-2 inhibitor alone or combined with dasatinib, ...
Di Minno M N D - - 2013
Magnetic resonance imaging (MRI) and ultrasonography (US) are increasingly used in haemophilia A (HA) to detect early joint changes. A total of 40 clinically asymptomatic joints, never involved by bleeding events ["healthy joints" (HJ)], were evaluated by MRI and, in parallel, by US in 20 young subjects with severe HA ...
Schaden Eva - - 2013
PURPOSE: Adequate monitoring of the effect of the direct thrombin inhibitor argatroban may facilitate individualized dosing and perioperative management of anticoagulation. Ecarin Clotting Time is proposed for this purpose, but has the major disadvantage of limited availability. There is a point-of-care applicable ecarin-activated test modification for rotational thrombelastometry (ROTEM®) which ...
Delorenzo Christine - - 2013
Pre-treatment differences in serotonergic binding between those who remit to antidepressant treatment and those who do not have been found using Positron Emission Tomography (PET). To investigate these differences, an exploratory study was performed using a second imaging modality, diffusion-weighted MRI (DW-MRI). Eighteen antidepressant-free subjects with Major Depressive Disorder received ...
Duncan K K Department of Pathology, University of Iowa Roy J and Lucille A Carver College of Medicine, Iowa City, IA, - - 2013
(18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) and computed tomography (CT) are useful imaging modalities for evaluating tumor progression and treatment responses in genetically engineered mouse models of solid human cancers, but the potential of integrated FDG-PET/CT for assessing tumor development and new interventions in transgenic mouse models of human blood cancers ...
Haslem Bryce D BD Department of Medicine, Division of Gastroenterology & Hepatology, Univeristy of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA. - - 2013
Eosinophilic esophagitis was first reported in 1978, and since then it has been increasingly recognized as one of the major etiologies for dysphagia, food impaction, and food regurgitation. To the best of our knowledge, no case of eosinophilic esophagitis (excluding esophageal eosinophilia not responsive to proton pump inhibitor treatment) has ...
Cho Steve Y - - 2012
Prostate-specific membrane antigen (PSMA) is a type II integral membrane protein expressed on the surface of prostate cancer (PCa) cells, particularly in androgen-independent, advanced, and metastatic disease. Previously, we demonstrated that N-[N-[(S)-1,3-dicarboxypropyl]carbamoyl]-4-(18)F-fluorobenzyl-L-cysteine ((18)F-DCFBC) could image an experimental model of PSMA-positive PCa using PET. Here, we describe the initial clinical experience ...
Adjobo-Hermans Merel J W - - 2012
Phospholipase C (PLC) β isoforms are implicated in various physiological processes and pathologies. However, mechanistic insight into the localization and activation of each of the isoforms is limited. Therefore, it is crucial to gain more in-depth knowledge as to the regulation of the different isoforms. Here we describe the subcellular ...
Yeh Hsin-Hsien HH Department of Experimental Diagnostic Imaging, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, - - 2013
Epigenetic modifications mediated by histone deacetylases (HDACs) play important roles in the mechanisms of different neurologic diseases and HDAC inhibitors (HDACIs) have shown promise in therapy. However, pharmacodynamic profiles of many HDACIs in the brain remain largely unknown due to the lack of validated methods for noninvasive imaging of HDAC ...
Desar Ingrid M E - - 2012
Selumetinib (AZD6244, ARRY-142886) is a potent, selective, uncompetitive inhibitor of MEK 1 / 2, part of the RAF/MEK/ERK protein kinase signal cascade, which is responsible for tumor. This pilot study was used to explore if (18)F-fluoro-l-thymidine (FLT), a thymidine analogue positron emission tomography (PET) tracer and a surrogate marker for ...
Schwarz Sebastian - - 2012
Iron oxide-based magnetic nanoparticles (MNPs) offer unique properties for cell tracking by magnetic resonance imaging (MRI) in cellular immunotherapy. In this study, we investigated the uptake of chemically engineered NPs into antigen-presenting dendritic cells (DCs). DCs are expected to perceive MNPs as foreign antigens, thus exhibiting the capability to immunologically ...
Nanni M - - 2011
Objectives: To report the antenatal pictures of a fetus with multiple intracranial lipomas. Methods: A 36-year-old primigravida, 33 weeks of gestation, was referred to our ultrasound laboratory due to sonographic suspicion of an intracranial hemorrhage. Results: At 2D and 3D ultrasound imaging, three separated round-shaped hyperechoic intracranial masses compatible with ...
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