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Bedoya Maria A MA 1 Department of Radiology, The Children's Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA - - 2014
OBJECTIVE. The purpose of this study is to use dynamic contrast-enhanced MRI to evaluate the perfusion characteristics of the proximal femur in the growing skeleton. MATERIALS AND METHODS. We evaluated 159 subjects (mean age, 5.67 years) who underwent a well-controlled protocol of contrast-enhanced MRI of the abdomen and hips. Perfusion ...
Kivrak Pfiffner Fatma F University Hospital Zurich, Plastic and Reconstructive Surgery, Zurich, Switzerland ; - - 2014
Adequate vascularization in biomaterials is essential for tissue regeneration and repair. Current models do not allow easy analysis of vascularization of implants in vivo, leaving it a highly desirable goal. A tool that allows to monitor the perfusion capacity of such biomaterials non-invasively in a cheap, efficient and reliable in ...
Bickelhaupt S S Department of Radiology, University Hospital Zürich, Zürich, Switzerland Department of Radiology, German Cancer Research Center (DKFZ), Heidelberg, - - 2014
Small bowel motility analyses using magnetic resonance imaging (MRI) could reduce current invasive techniques in animal studies and comply with the 'three Rs' rule for human animal experimentation. Thus we investigated the feasibility of in vivo small bowel motility analyses in mice using dynamic MRI acquisitions. All experimental procedures were approved ...
Schütz Gunnar G Bayer HealthCare AG, Berlin, - - 2014
When diagnosing cancer, assessing the nodal stage is tremendously important in determining the patient's prognosis. Computed tomography (CT) and magnetic resonance (MR) imaging (MRI) assessments of the regional lymph node (LN) size and shape are currently used for the initial nodal staging in clinical settings, although this approach has a ...
Jeun Minhong M Biomedical Research Institute, Korea Institute of Science and Technology (KIST) , Seoul 136-791, Republic of - - 2014
A superparamagnetic nanoferrite (SPNF) with high magnetic moment, AC magnetically induced heating (AC-heating) capacity, and good biocompatibility is the most vital part of magnetic fluid hyperthermia for utilizing it in the clinics. Herein, we precisely tune magnetic properties and AC-heating characteristics of MgxMn1-xFe2O4 SPNF via chemically controlling the cations' concentration ...
Abbas Kausar K Purdue University, School of Electrical and Computer Engineering, West Lafayette, Indiana, United States ; - - 2014
Long-term neurological damage as a result of head trauma while playing sports is a major concern for football athletes today. Repetitive concussions have been linked to many neurological disorders. Recently, it has been reported that repetitive sub-concussive events can be a significant source of accrued damage. Since football athletes can ...
Yu Y Y Department of Radiology, The First Affiliated Hospital of Soochow University, No. 188, Shi Zi Street, Suzhou 215006, Jiangsu, - - 2014
To explore the value of CT spectral imaging in the differential diagnosis of necrotic hepatocellular carcinoma (nHCC) and hepatic abscess (HA) during the arterial phase (AP) and portal venous phase (PP). Sixty patients with 36 nHCCs and 24 HAs underwent spectral CT during AP and PP. Iodine or water concentration ...
Mulligan Kyle R KR Orthopedics Research Laboratory of McGill University, Montreal General Hospital, 687 Pine Avenue West Suite L-4.65, Montreal, QC, H3A 1A1, - - 2014
The aim of the study was to investigate if axial T1ρ MR images had similar accuracy as established sagittal T1ρ MRI for the assessment of proteoglycan concentration and content in intervertebral degenerated discs (IDDs). T1ρ and T2-weighted MR images of 12 intervertebral discs (IVDs) from 3 harvested human lumbar spines ...
Dykes Thomas M TM Department of Radiology, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania. Electronic address: - - 2014
Establish 3 performance benchmarks for intravenous contrast extravasation during CT examinations: extravasation frequency, distribution of extravasation volumes, and severity of injury. Evaluate the effectiveness of implementing practice quality improvement (PQI) methodology in improving performance for these 3 benchmarks. The Society of Abdominal Radiology and ACR developed a registry collecting data ...
Yao Jie J Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, School of Biological Science and Medical Engineering, Beihang University, 100191 Beijing, China; National Key Lab of Virtual Reality Technology, Beihang University, 100191 Beijing, - - 2014
Patellofemoral (PF) maltracking is a critical factor predisposing to PF pain syndrome. Many novel techniques of measuring patellar tracking remain research tools. This study aimed to develop a method to measure the in vivo patellar tracking and finite helical axis (FHA) by using a static magnetic resonance (MR) based methodology. ...
Curcic J J Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; Division of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, - - 2014
The mechanism of reflux protection may involve a 'flap valve' at the oesophago-gastric junction (OGJ). To assess the effects of baclofen, a gamma-aminobutyric acid receptor type-B (GABA-B) agonist known to suppress reflux events, on the 'functional anatomy' of the OGJ and proximal stomach after a large test meal. Twelve healthy ...
Mariano Rodolfo Nicolás - - 2014
An amphiphilic Gd(III) complex has been efficiently loaded in polylactic-co-glycolic acid nanoparticles (PLGA-NP) to yield a novel, high sensitive MRI contrast agent for imaging guided drug delivery applications. As the Gd(III) complex is soluble in organic solvents, the nanoparticles were prepared as oil/water emulsions. PLGA-NP were stable, in buffer, for ...
Zeng ChengCai C College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325027, Zhejiang Province, P. R. - - 2014
A type of novel macromolecular colloid was prepared from gadolinium-based poly(l-succinimide) and gold nanoparticles (GNPs) with AuS covalent bonds. The colloid displayed improved stability in aqueous media and regular arrays in partial region. Moreover, these materials enhanced the contrast 9 times more than that of the corresponding uncoated Au compound ...
Buchenberg Waltraud B WB Department of Radiology, University Medical Center Freiburg, Medical Physics, Freiburg, - - 2014
Blood flow causes induced voltages via the magnetohydrodynamic (MHD) effect distorting electrograms (EGMs) made during magnetic resonance imaging. To investigate the MHD effect in this context MHD voltages occurring inside the human heart were simulated in an in vitro model system inside a 1.5 T MR system. The model was ...
Nsanzineza I I Department of Physics, Syracuse University, Syracuse, New York 13244-1130, - - 2014
Vortices trapped in thin-film superconducting microwave resonators can have a significant influence on the resonator performance. Using a variable-linewidth geometry for a weakly coupled resonator, we are able to observe the effects of a single vortex trapped in the resonator through field cooling. For resonant modes where the vortex is ...
Shemesh Noam N Department of Chemical Physics, Weizmann Institute of Science, Rehovot, - - 2014
Interruptions in cerebral blood flow may lead to devastating neural outcomes. Magnetic resonance has a central role in diagnosing and monitoring these insufficiencies, as well as in understanding their underlying metabolic consequences. Magnetic resonance spectroscopy (MRS) in particular can probe ischemia via the signatures of endogenous metabolites including lactic acid ...
Lim Elizabeth Yenn Lynn EY ORL Department, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia, - - 2014
High acoustic noise level is one of the unavoidable side effects of 3 T magnetic resonance imaging (MRI). A case of hearing loss after 3 T MRI has been reported in this institution and hence this study. The objective of this study was to determine whether temporary threshold shift (TTS) in high ...
van Grinsven S S Department of Orthopaedics, Rijnstate Hospital, PO Box 9555, 6800 TA, Arnhem, The Netherlands. Electronic address: - - 2014
To prospectively evaluate the influence of observer experience, consensus assessment, and abduction and external rotation (ABER) view on the diagnostic performance of magnetic resonance arthrography (MRA) in patients with traumatic anterior-shoulder instability (TASI). Fifty-eight MRA examinations (of which 51 had additional ABER views) were assessed by six radiologists (R1-R6) and ...
Lugez Elodie E Laboratory for Percutaneous Surgery, School of Computing, Queen's University, Kingston, ON, K7L 3N6, - - 2014
Electromagnetic (EM) tracking of instruments within a clinical setting is notorious for fluctuating measurement performance. Position location measurement uncertainty of an EM system was characterized in various environments, including control, clinical, cone beam computed tomography (CBCT), and CT scanner environments. Static and dynamic effects of CBCT and CT scanning on ...
Wijlemans Joost W JW From the *Department of Radiology, and †Imaging Division, University Medical Center Utrecht, Utrecht, The Netherlands; ‡Philips Medical Systems MR, Vantaa, Finland; and §Image Sciences Institute, University Medical Center Utrecht, Utrecht, The - - 2014
Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) allows for noninvasive thermal ablation under real-time temperature imaging guidance. The purpose of this study was to assess the feasibility and safety of MR-HIFU ablation of liver tissue in a clinically acceptable setting. The experimental protocol was designed with a clinical ablation procedure of ...
Smuck Matthew M PM&R Section, Department of Orthopaedic Surgery, Stanford University, Redwood City, California, - - 2014
To quantitatively evaluate interval magnetic resonance imaging (MRI) changes in disc morphology following plasma-mediated percutaneous discectomy. A retrospective comparison of pretreatment and posttreatment MRIs at a single university spine clinic. From a group of 60 consecutively treated patients, 15 met the study inclusion and exclusion criteria. All had either failed ...
Osti Michael M Department for Trauma Surgery and Sports Traumatology, Academic Hospital Feldkirch, Carinagasse 47, 6800, Feldkirch, Austria, - - 2014
For intra- and postoperative evaluation of precise and anatomic graft tunnel position, radiographs (XR) and computed tomography (CT) scans have been suggested. The purpose of this study was to evaluate the reliability and validity of XR and CT for quality assessment following PCL reconstruction. Postoperative radiographs and CT scans were ...
Iwaki Shimpei S Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. - - 2014
Gadolinium(iii) ion (Gd(3+)) complexes are widely used as contrast agents in magnetic resonance imaging (MRI), and many attempts have been made to couple them to sensor moieties in order to visualize biological phenomena of interest inside the body. However, the low sensitivity of MRI has made it difficult to develop ...
Shi Dejing D Department of Ophthalmology, Forth Affiliated Hospital of Harbin Medical University, Harbin, P.R. - - 2014
The aim of this study was to evaluate effects of intermediate frequency magnetic fields (IFMF) generated by a wireless power transmission (WPT) based on magnetic resonance from the perspective of cellular genotoxicity on cultured human lens epithelial cells (HLECs). We evaluated the effects of exposure to 90 kHz magnetic fields at ...
Fries Peter P Clinic of Diagnostic and Interventional Radiology (Geb. 50.1), Saarland University Medical Center, Homburg, - - 2014
Magnetic resonance imaging (MRI) performed at ultra-high field strengths beyond 3 Tesla (T) has become increasingly prevalent in research and preclinical applications. As such, the inevitable clinical implementation of such systems lies on the horizon. The major benefit of ultra-high field MRI is the markedly increased signal-to-noise ratios achievable, enabling acquisition ...
Siebenrock Klaus A KA Department of Orthopaedic Surgery, Inselspital, University of Bern, Freiburgstrasse, 3010, Bern, Switzerland, - - 2014
Cam-type femoroacetabular impingement (FAI) resulting from an abnormal nonspherical femoral head shape leads to chondrolabral damage and is considered a cause of early osteoarthritis. A previously developed experimental ovine FAI model induces a cam-type impingement that results in localized chondrolabral damage, replicating the patterns found in the human hip. Biochemical ...
Tampieri Anna - - 2014
A bio-inspired mineralization process was applied to develop biomimetic hybrid scaffolds made of (Fe2+/Fe3+)-doped hydroxyapatite nanocrystals nucleated on self-assembling collagen fibers and endowed with superparamagnetic properties minimizing the formation of potentially cytotoxic magnetic phases such as magnetite or other iron oxide phases. Magnetic composites were prepared at different temperatures and ...
Mulas Gilberto G Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy; Porto Conte Ricerche Srl, Tramariglio, Alghero (SS), - - 2014
Purpose: To describe and quantify the different relaxation mechanisms operating in suspensions of liposomes that encapsulate paramagnetic lanthanide(III) complexes. Theory and Methods: The transverse relaxation rate of lanthanide-loaded liposomes receives contribution from the exchange between intraliposomal and bulk water protons, and from magnetic susceptibility effects. Phospholipids vesicles encapsulating different Ln(III)-HPDO3A ...
Zhang Zhentao Z From the Department of Internal Medicine, University of Texas Southwestern at Austin, Austin, - - 2014
Paradichlorobenzene (PDB) is an aromatic compound found in several household insect repellents and deodorizers. Paradichlorobenzene may cause dependence and damage when inhaled or ingested. Prior cases of PDB neurotoxicity involved ingestion or inhalation of mothballs or occupational exposure. We report the first case of PDB neurotoxicity from chronic toilet bowl ...
Romano Andrea A San Raffaele Foundation Rome, Rehabilitation Facility Ceglie Messapica, Progetto Merit RBNE08E8CZ, Via della Pisana 235, 00163, Rome, Italy, - - 2014
To assess what kind of information MR examination in flexed and extended positions provides in Down syndrome subjects with suspected cranio-cervical instability. Between 2005 and 2008, 35 subjects with DS were recruited in the study. Ethics committee approval was granted and a signed informed consent was obtained from the parents. ...
Gräfe J L JL Department of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, Ontario, Canada - - 2014
Gadolinium (Gd) based contrast agents are routinely used as part of many magnetic resonance imaging (MRI) procedures. The widespread use of these agents and concerns about Gd toxicity, motivated us to develop a monitoring procedure that could non-invasively measure quantitatively potential retention of toxic free Gd in tissues after use ...
Carrera Inés I Division of Diagnostic Imaging, Vetsuisse Faculty, University of Zurich, 8057 Zurich, - - 2014
Objective-To investigate clinical use of proton magnetic resonance spectroscopy ((1)H MRS) and to compare metabolic brain bioprofiles of dogs with and without hepatic encephalopathy. Animals-6 dogs with hepatic encephalopathy and 12 control dogs. Procedures-Conventional MRI and single-voxel (1)H MRS were performed with a 3-T magnet. Images for routine MRI planes ...
Fujiwara Shunro S Neurospin, Bâtiment 145, CEA-Saclay, Gif-sur-Yvette, 91191 Gif-sur-Yvette, France; Department of Neurosurgery, Iwate Medical University, 19-1 Uchimaru, Morioka, 0208505 Iwate, - - 2014
Pathological iron deposits in the brain, especially within basal ganglia, are linked to severe neurodegenerative disorders like Parkinson's disease. As iron induces local changes in magnetic susceptibility, its presence can be visualized with magnetic resonance imaging (MRI). The usual approach, based on iron induced changes in magnetic relaxation (T2/T2'), is ...
Kim Sung Mo SM Department of Radiology, Chonnam National University Hwasun Hospital, Hwasun 519-763, - - 2014
To compare gadoxetic acid injection rates of 0.5 mL/s and 1 mL/s for hepatic arterial-phase magnetic resonance (MR) imaging. In this prospective study, 101 consecutive patients with suspected focal liver lesions were included and randomly divided into two groups. Each group underwent dynamic liver MR imaging using a 3.0-T scanner ...
Meng Fan F Department of Orthopeadics,Tianjin First Central Hospital,Tianjin 300192,China; Institute of Orthopeadics,Chinese PLA General Hospital,Beijing - - 2014
Objective To establish a new animal model of osteonecrosis of the femoral head by local ethanol injection in emu. Methods Eight milliliter ethanol was injected slowly to the operated femoral head with customized probe in twenty adult male emus. Postoperatively,hip magnetic resonance imaging was performed at 1,4,8,12 weeks. After emus ...
von Morze Cornelius C Department of Radiology and Biomedical Imaging, University of California, San Francisco. Electronic address: - - 2014
In this work we demonstrate for the first time directly detected manganese-55 ((55)Mn) MRI using a clinical 3T MRI scanner designed for human hyperpolarized (13)C clinical studies with no additional hardware modifications. Due to the similar frequency of the (55)Mn and (13)C resonances, the use of aqueous permanganate for large, ...
Gharagouzloo Codi Amir CA Nanomedicine Science and Technology Center, Northeastern University, Boston, Massachusetts, USA; Department of Bioengineering, Northeastern University, Boston, Massachusetts, - - 2014
Conventional MRI using contrast agents is semiquantitative because it is inherently sensitive to extravoxular susceptibility artifacts, field inhomogeneity, partial voluming, perivascular effects, and motion/flow artifacts. Herein we demonstrate a quantitative contrast-enhanced MRI technique using ultrashort time-to-echo pulse sequences for measuring clinically relevant concentrations of ferumoxytol, a superparamagnetic iron oxide nanoparticle ...
Dreiser Jan J Institute of Condensed Matter Physics, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne (Switzerland); Swiss Light Source, Paul Scherrer Institut, 5232 Villigen PSI (Switzerland). - - 2014
The low-temperature magnetic properties of the endohedral metallofullerene HoSc2 N@C80 have been studied by superconducting quantum interference device (SQUID) magnetometry. Alternating current (ac) susceptibility measurements reveal that this molecule exhibits slow relaxation of magnetization in a small applied field with timescales in the order of milliseconds. The equilibrium magnetic properties ...
Ochi Tomoko T Department of Radiology, Nara Medical - - 2014
Purpose: As stereotactic radiotherapy (SRT) becomes widespread, precise information including number, location, and margin of lesions is required when magnetic resonance (MR) imaging of brain metastasis is performed. We compare methods using 2 separate injections and a single injection for the administration of a double dose of contrast medium for ...
Yamaguchi Oura Mao M Department of Neurology and Gerontology, Institute for Biomedical Sciences, Iwate Medical University, Morioka, Japan. Electronic address: - - 2014
Cilostazol is an antiplatelet agent that can induce the regression of atherosclerosis. However, its long-term effects on plaque involution of the cervical carotid arteries remain unknown. Thus, we aimed to evaluate the effect of long-term cilostazol administration on carotid plaques using quantitative magnetic resonance (MR) plaque imaging. Sixteen consecutive patients ...
Wang Yu - - 2014
CXCR4/SDF-1 has been found to be related to the initiation of neuroinflammation in ischemic brain. Herein, we aimed to monitor the changes of neuorinflammation after AMD3100 treatment using TSPO specific PET tracer in a mouse model of stroke. The transient MCAO model was established with Balb/C mice. Success of the ...
Gendler Andrew A WestVet Emergency and Specialty Center, Garden City, ID - - 2014
Comprehensive evaluation of canine elbow joint dysfunction includes assessment of articular cartilage, which can noninvasively be performed with contrast arthrography. Aims of this prospective study were to compare positive contrast computed tomographic (CT) arthrography and histomorphometry measures of cartilage thickness in normal canine elbows, and to determine the optimal contrast ...
Wang Z Z Institute for Medical Science and Technology, University of Dundee, Dundee, - - 2014
Feasibility studies are needed to demonstrate that safe and effective manipulation of bowel during Minimal Access Surgery (MAS) can be obtained by use of magnetic force. This paper characterises two classes of magnetic particles: stainless steel microparticles (SS-μPs) and iron oxide nanoparticles (IO-nPs) in terms of their magnetisation, chemical composition, ...
Shen Lihua L Department of Biomaterials, College of Materials, Xiamen University, Xiamen, 361005, P.R. - - 2014
Self-assembly of viral coating proteins encapsulating functional nanoparticles provides a new class of biomaterials with robust chemical and physical properties for potential applications in functional imaging, and therapeutic or diagnostic agent delivery. Herein, a straightforward method is demonstrated for efficient encapsidation of magnetic nanoparticles into the engineered virus-like particle (VLP) ...
Do Mi Ae MA Department of Advanced Organic Materials Science and Engineering, Kyungpook National University, Daegu 702-701, Republic of - - 2014
The development of iron oxide nanoparticles (IONPs) with enhanced r2 relaxivity is important for achieving greater sensitivity in in vivo magnetic resonance (MR) imaging. In this study, it was considered that polyethyleneimine (PEI) could play a role in varying the particle and cluster sizes in IONP synthesis, leading to different ...
Meshcheriakova O O Graduate School of Excellence "Materials Science in Mainz" Johannes Gutenberg-Universtität, 55099 Mainz, Germany and Max-Planck-Institut für Chemische Physik fester Stoffe, Nöthnitzer Strasse 40, 01187 Dresden, - - 2014
Noncollinear magnets provide essential ingredients for the next generation memory technology. It is a new prospect for the Heusler materials, already well known due to the diverse range of other fundamental characteristics. Here, we present a combined experimental and theoretical study of novel noncollinear tetragonal Mn_{2}RhSn Heusler material exhibiting unusually ...
Sasaki Daisuke D Graduate School of Engineering, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657-8501, - - 2014
Central metabolite profiles from glucose in microbial communities during methanogenic process were compared between a stable methanogenic reactor (MR) and a deteriorated reactor (DR). The concentrations of intracellular metabolites related to the Embden-Meyerhof and pentose phosphate pathways, with the exception of pyruvate, remained high in the MR, showing increased carbon ...
Morgan Alexandra R AR Bioxydyn Ltd, Manchester, UK; Centre for Imaging Sciences and Biomedical Imaging Institute, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK. Electronic address: - - 2014
Oxygen-enhanced MRI (OE-MRI) biomarkers have potential value in assessment of COPD, but need further evaluation before treatment-induced changes can be interpreted. The objective was to evaluate how OE-MRI parameters of regional ventilation and oxygen uptake respond to standard pharmacological interventions in COPD, and how the response compares to that of ...
Bharucha Adil E AE Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R.) Program, Division of Gastroenterology and Hepatology, College of Medicine, Mayo Clinic, 200 First St. S.W., Rochester, MN 55905, United States. Electronic address: - - 2014
To assess if erythromycin increases gastric emptying and hence improves small intestinal distention during MR enterography. Gastric, small intestinal, and large intestinal volumes were assessed with MR after neutral oral contrast (1350ml in 45min) and balanced randomization to erythromycin (200mg i.v., age 31±3y, 13 females), or placebo (37±3y, 13 females) ...
Molan Abdul-Lateef - - 2014
The effects of condensed tannins (CTs) extracted from pine bark on egg hatching, larval development and the viability of infective L3 larvae of Trichostrongylus colubriformis (Giles, 1892) and Teladorsagia circumcincta (Stadelmann, 1894) (syn. Ostertagia circumcincta) were evaluated using in vitro bioassays. Significant inhibitory effects of CTs were obtained on the ...
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