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Bülow Robin R Department of Radiology and Neuroradiology, University Medicine, Ernst Moritz Arndt University Greifswald, Ferdinand-Sauerbruch-Straße 1, Greifswald, 17475, Germany, - - 2014
To investigate the frequency of pancreatic duct (PD) variants and their effect on pancreatic exocrine function in a population-based study using non-invasive secretin-stimulated magnetic resonance cholangiopancreatography (sMRCP). Nine hundred and ninety-five volunteers, 457 women and 538 men, aged 51.9 ± 13.4 years, underwent navigator-triggered, T2-weighted, 3D turbo spin echo MRCP on a 1.5 T ...
Kim Ji Eun JE Department of Radiology, Gyeongsang National University School of Medicine, Jinju, - - 2014
The purpose of the study is to describe the CT findings of poorly differentiated (PD) colorectal adenocarcinoma (CRAC) compared with those of well- (WD) or moderately differentiated (MD) CRAC. One hundred and thirteen patients with pathologically proven PD (n = 26), WD (n = 35), or MD (n = 52) CRACs and who had undergone preoperative, ...
Prodoehl Janey J Physical Therapy Program, Midwestern University, 555 31st Street, Downers Grove, IL, - - 2014
Neuroimaging advances over the past several decades have provided increased understanding of the structural and functional brain changes that occur with Parkinson's disease (PD). Examination of resting state functional magnetic resonance imaging (rs-fMRI) provides a noninvasive method that focuses on low-frequency spontaneous fluctuations in the blood-oxygenation-level-dependent signal that occurs when ...
Suto Hirofumi H Corporate Research and Development Center, Toshiba Corporation, Komukai-Toshiba-cho, Saiwai-ku, Kawasaki 212-8582, - - 2014
Technology for detecting the magnetization direction of nanoscale magnetic material is crucial for realizing high-density magnetic recording devices. Conventionally, a magnetoresistive device is used that changes its resistivity in accordance with the direction of the stray field from an objective magnet. However, when several magnets are near such a device, ...
Xiao Yiming Y McConnell Brain Imaging Center, Montreal Neurological Institute and Hospital, 3801 University Street, Montreal, QC, H3A 2B4, Canada, - - 2014
Parkinson's disease (PD) is the second leading neurodegenerative disease after Alzheimer's disease. In PD research and its surgical treatment, such as deep brain stimulation (DBS), anatomical structural identification and references for spatial normalization are essential, and human brain atlases/templates are proven highly instrumental. However, two shortcomings affect current templates used ...
Fernandez Laura - - 2014
Controlling anisotropy and exchange coupling in patterned magnetic nanostructures is the key for developing advanced magnetic storage and spintronic devices. We report on the antiferromagnetic interaction between a Co nanodot array and its supporting GdAu2 nanotemplate that induces large anisotropy values in individual Co nanodots. In clear contrast with non-magnetic ...
Capín Esmeralda E Unidad de Imagen, Área del Corazón, Hospital Universitario Central de Asturias, Oviedo, Asturias, - - 2014
Caseous calcification of the mitral annulus is an infrequent echocardiographic finding. The differential diagnosis includes other entities like tumors, abscess or thrombus. Both cardiac CT and cardiac MRI may be useful for its definitive diagnosis.
Feng Jie-Ying JY Department of Radiology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, PR - - 2014
The putaminal abnormalities detected on 1.5 T magnetic resonance imaging (MRI), such as putaminal atrophy, slit-like hyperintense rim, and hypointensity in the putamen on T2-weighted (T2W) imaging are important signs on differentiating multiple system atrophy with parkinsonism (MSA-P) from Parkinson's disease (PD). However, the putaminal abnormalities may have different manifestations on ...
Sako Wataru W Center for Neurosciences, The Feinstein Institute for Medical Research, Manhasset, NY, - - 2014
Background: Parkinson's disease (PD) involves the degeneration of dopaminergic neurons in substantia nigra compacta. However, it is still a contentious issue whether magnetic resonance imaging (MRI) can detect the nigral volume loss in PD patients. Objective: We synthesized the results of published research on SN volumetry using a meta-analysis method ...
Kamagata Koji K Department of Radiology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan, - - 2014
Diffusional kurtosis imaging (DKI) is a more sensitive technique than conventional diffusion tensor imaging (DTI) for assessing tissue microstructure. In particular, it quantifies the microstructural integrity of white matter, even in the presence of crossing fibers. The aim of this preliminary study was to compare how DKI and DTI show ...
Hsiao Ing-Tsung IT Healthy Aging Research Center, and Department of Medical Imaging and Radiological Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan; Molecular Imaging Center and Department of Nuclear Medicine, Chang Gung Memorial Hospital, Taoyuan, - - 2014
(99m)Tc-TRODAT-1 is the first clinical routine (99m)Tc radiopharmaceutical to evaluate dopamine neurons loss in Parkinson's disease (PD). (18)F-AV-133 is a novel PET radiotracer targeting the vesicular monoamine transporter type 2 (VMAT2) to detect monoaminergic terminal reduction in PD patients. The aim of this study is to compare both images in ...
Choo Hye Jung HJ 1 Department of Radiology, College of Medicine, Inje University Busan Paik Hospital, Gaegeum-dong Jin-gu, Busan 614-735, Republic of - - 2014
OBJECTIVE. The purpose of this study is to evaluate the frequency and MRI characteristics of multibanded anterior talofibular ligaments in normal ankles and to characterize the tear types of multibanded anterior talofibular ligaments in sprained ankles using a 3D isotropic proton density (PD)-weighted fast spin-echo (FSE) MRI sequence. SUBJECTS AND ...
Schwarz Stefan T ST Radiological Sciences, Division of Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, United - - 2014
There is no well-established in vivo marker of nigral degeneration in Parkinson's disease (PD). An ideal imaging marker would directly mirror the loss of substantia nigra dopaminergic neurones, which is most prominent in sub-regions called nigrosomes. High-resolution, iron-sensitive, magnetic resonance imaging (MRI) at 7T allows direct nigrosome-1 visualisation in healthy ...
Kim Borah B Department of Psychiatry, CHA Bundang Medical Center, CHA University, Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of - - 2014
The frontal cortex might play an important role in the fear network, and white matter (WM) integrity could be related to the pathophysiology of panic disorder (PD). A few studies have investigated alterations of WM integrity in PD. The aim of this study was to determine frontal WM integrity differences ...
Meijer Frederick Ja FJ Department of Radiology, Nuclear medicine, Radboud University Nijmegen Medical Center, Geert Grooteplein 10, 6500 HB, Nijmegen, The - - 2014
In this review article, conventional brain MRI and advanced MRI techniques in Parkinson`s disease (PD) are discussed, with emphasis on clinical relevance. Conventional brain MRI sequences generally demonstrate limited abnormalities specific for PD and in clinical practice brain MRI is mainly used to exclude other pathology. Possibly, brain MRI at ...
Salvatore C - - 2013
Supervised machine learning has been proposed as a revolutionary approach, for identifying sensitive medical image biomarkers (or combination of them) allowing for automatic, diagnosis of individual subjects. The aim of this work was to assess the feasibility of a supervised, machine learning algorithm for the assisted diagnosis of patients with ...
El Habnouni Sarah - - 2013
Hydrophobic macromolecular contrast agents (MMCAs) are highly desirable to provide safe and efficient magnetic resonance (MR) visibility to implantable medical devices. In this study, we report on the synthesis and evaluation of novel biodegradable poly(ε-caprolactone)-based MMCAs. Poly(α-propargyl-ε-caprolactone-co-ε-caprolactone)s containing 2, 5 and 10 mol% of propargyl groups have been prepared by ...
Benadiba Marcel - - 2013
The pathophysiology of Parkinson's disease (PD) has not yet been completely elucidated. However, during the past few years, significant progress has been made in understanding the intra- and extracellular mechanisms by which proteins such as alpha-synuclein and neuroinflammatory molecules may display impaired function and/or expression in PD. Recent developments in ...
Wang Deng-Bin DB Department of Radiology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China. - - 2013
To determine the magnetic resonance cholangiopancreatography (MRCP) and magnetic resonance imaging (MRI) features of pancreatitis with pancreas divisum (PD) and the differences vs pancreatitis without divisum. Institutional review board approval was obtained and the informed consent requirement was waived for this HIPAA-compliant study. During one year period, 1439 consecutive patients ...
Koo Chiwan - - 2013
Magnetic resonance (MR) microscopy typically employs microcoils for enhanced local signal-to-noise ratio (SNR). Planar (surface) microcoils, in particular, offer the potential to be configured into array elements as well as to enable the imaging of extremely small samples because of the uniformity and precision provided by microfabrication techniques. Microcoils, in ...
Lavdas Eleftherios - - 2013
The purpose of this study, is to compare the sequences: 1) proton density (PD) BLADE (BLADE is a PROPELLER-equivalent implementation of the Siemens Medical System) with fat saturation (FS) coronal (COR), 2) PD FS COR, 3) multi-planar reconstruction (MPR) with 3mm slice thickness and 4) multi-planar reconstruction (MPR) with 1.5mm ...
Blazejewska Anna I AI Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, Nottingham, - - 2013
This study assessed whether high-resolution 7 T MRI allowed direct in vivo visualization of nigrosomes, substructures of the substantia nigra pars compacta (SNpc) undergoing the greatest and earliest dopaminergic cell loss in Parkinson disease (PD), and whether any disease-specific changes could be detected in patients with PD. Postmortem (PM) midbrains, ...
Sterling Nicholas W - - 2013
Parkinson's disease (PD) is marked pathologically by nigrostriatal dopaminergic terminal loss. Histopathological and in vivo labeling studies demonstrate that this loss occurs most extensively in the caudal putamen and caudate head. Previous structural studies have suggested reduced striatal volume and atrophy of the caudate head in PD subjects. The spatial distribution ...
Christopher Leigh - - 2013
Cognitive impairment occurs frequently in Parkinson's disease (PD) and the concept of Mild Cognitive Impairment in PD (PD-MCI) has recently emerged. Patients with mild impairment are at risk of developing dementia, and thus it is a topic of growing interest. Many previous studies have investigated the neural correlates of cognitive ...
Baglieri A - - 2013
Magnetic resonance imaging (MRI) provides an in vivo assessment of cortical and subcortical regions affected in Parkinson's disease (PD). This review summarizes the most important conventional and non-conventional MRI techniques applied in this field. Standard neuroimaging techniques have played a marginal role in the diagnosis and follow-up of PD, essentially ...
Catana Ciprian C Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA. - - 2013
PET and MR imaging are modalities routinely used for clinical and research applications. Integrated scanners capable of acquiring PET and MR imaging data in the same session, sequentially or simultaneously, have recently become available for human use. In this article, we describe some of the technical advances that allowed the ...
Martinez Gary V GV Department of Cancer Imaging and Metabolism, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, - - 2013
A scaffold bearing eight terminal alkyne groups was synthesized from sucrose, and copies of an azide-terminated Gd-DOTA complex were attached via copper(I)-catalyzed azide-alkyne cycloaddition. The resulting contrast agent (CA) was administered by gavage to C3H mice. Passage of the CA through the gastrointestinal (GI) tract was followed by T1-weighted magnetic ...
Orimo Satoshi - - 2013
Brain MRI is essential for differentiating Parkinson's disease (PD) from other parkinsonian syndromes. The purpose of performing brain MRI is not to make a diagnosis of PD but is to exclude other parkinsonian syndromes. Recently, several new MRI techniques such as voxel based morphometry, relaxometry, magnetization transfer, spectroscopy, tractography, and ...
Garraux Gaëtan G Cyclotron Research Centre, Sart Tilman B30, University of Liège, 4000 Liège, Belgium ; Department of Neurology, University Hospital Centre, Sart Tilman B35, 4000 Liège, - - 2013
Most available pattern recognition methods in neuroimaging address binary classification problems. Here, we used relevance vector machine (RVM) in combination with booststrap resampling ('bagging') for non-hierarchical multiclass classification. The method was tested on 120 cerebral (18)fluorodeoxyglucose (FDG) positron emission tomography (PET) scans performed in patients who exhibited parkinsonian clinical features ...
Chiavazza Enrico - - 2012
Scalar coupling relaxation, which is usually only associated with closely resonant nuclei (e.g., (79)Br-(13)C), can be a very effective relaxation mechanism. While working on hyperpolarized [5-(13)C]glutamine, fast liquid-state polarization decay during transfer to the MRI scanner was observed. This behavior could hypothetically be explained by substantial T(1) shortening due to ...
Ziegler David A - - 2012
OBJECTIVE To test the hypothesis that degeneration of the substantia nigra pars compacta (SNc) precedes that of the cholinergic basal forebrain (BF) in Parkinson disease (PD) using new multispectral structural magnetic resonance (MR) imaging tools to measure the volumes of the SNc and BF. DESIGN Matched case-control study. SETTING The ...
Mancinelli M - - 2012
The interferometric coupling of pairs of resonators in a resonator sequence generates coupled ring induced transparency (CRIT) resonances. These have quality factors an order of magnitude greater than those of single resonators. We show that it is possible to engineer CRIT resonances in tapered SCISSOR (Side Coupled Integrated Space Sequence ...
Burbidge S - - 2013
To assess the relative roles of computed tomography (CT) and diagnostic laparoscopy in the staging process of patients with potentially curable gastric cancer. Fifty-two patients underwent laparoscopy and CT as part of staging; 36 patients underwent surgery without laparoscopy. Pathological findings at laparoscopy or surgery were compared with initial CT ...
Pagan Fernando L - - 2012
Current diagnostic modalities in Parkinson's disease (PD) are limited by the fact that they identify PD by the presence of motor symptoms; by this point, over 60 percent of all dopamine neurons within specific regions of the basal ganglia may have been lost. Nonmotor symptoms manifest in PD long before ...
Hundt Walter - - 2012
We have investigated the effect of targeted gene therapy on the melanoma cell line M21, using a combination of bioluminescence imaging (BLI) and magnetic resonance imaging (MRI). M21 cells transfected with a plasmid containing either an hsp70 (Hspa1b) or a CMV promoter fragment, along with the luciferase reporter gene, were ...
Chen Huanjun - - 2012
A fano resonance is observed in highly symmetric nanostructures comprising Au nanosphere cores and dielectric shells. It arises from the interference between the narrow plasmon resonance of the Au nanosphere core and the broad scattering background of the dielectric shell. The Fano resonance behavior is dependent on the gap distance ...
Kato Maho - - 2012
To evaluate computed tomography (CT) and magnetic resonance (MR) imaging findings of posterior mediastinal ganglioneuromas. Of 14 pathologically confirmed ganglioneuromas seen in 13 patients, 13 were evaluated by CT images with and without contrast, 11 were evaluated with conventional spin-echo MR images, and 5 were evaluated with contrast-enhanced MR examination. ...
Duigenan Shauna - - 2012
The CT and MRI features of ovarian torsion are illustrated with gross pathologic correlation. Ovarian enlargement with or without an underlying mass is the finding most frequently associated with torsion, but it is nonspecific. A twisted pedicle, although not often detected on imaging, is pathognomonic when seen. Subacute ovarian hemorrhage ...
Yong Ee Ling - - 2012
Ozonation is widely employed in water treatment to purify water. The R(ct) concept, which is defined as the ratio of OH exposure to ozone exposure, has been commonly used to quantify the OH concentration generating from ozone decomposition and model the removal of organic pollutant. Due to its empirical nature, ...
Li Xinchun - - 2012
To analyze the imaging findings of ovarian thecoma and to better understand the tumor features based on aspect of computed tomography and magnetic resonance images. Nineteen ovarian thecomas confirmed by histopathologic examination were analyzed retrospectively. Image characteristics were analyzed and compared with those of the pathologic features. The mean diameter ...
Jaganathan Sriram - - 2012
The synovium, a specialized vascular tissue, lines the diarthrodial joints, bursae, and tendon sheaths of the body. It helps in nourishment of articular structures. The synovium is affected by a variety of disorders that can be either localized or systemic. Although normal synovium is barely perceptible on magnetic resonance imaging, ...
Mogensen Signe Sloth - - 2012
Central precocious puberty may result from organic brain lesions, but is most frequently of idiopathic origin. Clinical or biochemical factors which could predict a pathological brain MRI in girls with CPP have been searched for. With the recent decline in age at pubertal onset among US and European girls, it ...
Skorpil Mikael - - 2012
Pathological studies have shown that Parkinson's disease (PD) at early stages affects the olfactory bulb (OB) followed by an involvement of substantia nigra (SN) and other brain regions. Emerging imaging methodologies detect alterations in certain brain regions of living PD patients, which may support proper diagnosis and monitor disease progression. ...
Sumikawa Hiromitsu - - 2011
OBJECTIVES: The aim of this study was to correlate high-resolution CT (HRCT) findings at the site of biopsy with the whole lung CT and pathologic diagnoses in usual interstitial pneumonia (UIP) and nonspecific interstitial pneumonia (NSIP). METHODS: The study included 35 patients (25 UIP and 10 NSIP) diagnosed both pathologically ...
Yamamoto Asako - - 2011
Chondromyxoid fibroma (CMF) of the rib is exceedingly unusual and few detailed image findings have been reported. Plain radiograph, computed tomography (CT), and magnetic resonance (MR) imaging findings and pathological aspects of a case of CMF of the right 2nd rib in a 15-year-old woman are reported, which was difficult ...
Campanella H - - 2011
We report on a new approach for magnetic imaging, highly sensitive even in the presence of external, strong magnetic fields. Based on FIB-assisted fabricated high-aspect-ratio rare-earth nanomagnets, we produce groundbreaking magnetic force tips with hard magnetic character where we combine a high aspect ratio (shape anisotropy) together with strong crystalline ...
Joutsa Juho - - 2011
Several magnetic resonance imaging (MRI) studies in substance use disorders have shown brain white matter integrity abnormalities, but there are no studies in pathological gambling, a form of behavioral addiction. Our objective was to investigate possible changes in regional brain gray and white matter volumes, and axonal white matter integrity ...
Sze Kong Hung - - 2011
One way to overcome the intrinsically low sensitivity of Nuclear Magnetic Resonance spectroscopy is to enhance the signal by dynamic nuclear polarization (DNP), where the polarization of high-gyromagnetic ratio (γ) electrons is transferred to the surrounding nuclei using microwave (MW) irradiation. Recent developments in DNP instrumentations and applications have shown ...
O'Brien Thomas - - 2011
OBJECTIVE: To compare digital radiography (DR), computed tomography (CT), and magnetic resonance imaging (MRI) for detection of pathology of the distal aspect of the third metacarpal bone (MC3) and to assess whether arthrography would improve detection of articular cartilage or subchondral bone cracking. STUDY DESIGN: Cross-sectional study. SAMPLE POPULATION: Limb ...
Sacerdote Michael G - - 2011
Adrenal hemorrhage is rarely suspected clinically, exhibits no specific clinical symptoms or laboratory findings, and yet is immediately life-threatening when bilateral. Recognition of adrenal hematomas is complicated by the variable appearance of these lesions. We survey the ways in which adrenal hematomas can appear on CT and provide strategies for ...
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