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Michel Krijn B KB Department of Biology, Universiteit Antwerpen, Universiteitsplein 1, B-2610, Antwerpen, - - 2014
Cover illustration. Skeletal body plan of the Atlantic mudskipper (Periophthalmus barbarus) from a lateral view. The mudskipper uses its fish feeding apparatus to successfully feed in the terrestrial environment. Each color represents a unit of fused or otherwise firmly interconnected ossified structures. Presented from a micro CT-scan using Amira (FEI ...
Lee Sonia S Musculoskeletal Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, California, - - 2014
To develop a semi-quantitative MR-based hip osteoarthritis (OA) evaluation system (Scoring hip osteoarthritis with MRI, SHOMRI), and to test its reproducibility and face validity. The study involved 98 subjects with informed consent. Three-Tesla MR imaging of hip was performed in three planes with intermediate-weighted fat saturated FSE sequences. Two radiologists ...
Mhlanga Joyce C JC Division of Nuclear Medicine, The Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, - - 2014
The aim of this study was to prospectively determine the feasibility and compare the novel use of a positron emission mammography (PEM) scanner with standard PET/CT for evaluating hand osteoarthritis (OA) with (18)F-FDG. Institutional review board approval and written informed consent were obtained for this HIPAA-compliant prospective study in which ...
Yoon Hai-Jeon HJ From the Department of Nuclear Medicine, Ewha Womans University School of Medicine, Seoul, - - 2014
F-FDG and Tc-MDP are excreted through the renal system. For the most part, radiotracers are uniformly distributed in the bladder; however, their distribution can exhibit unique patterns in certain situations. We present a case of stratified urine activity in a floppy neobladder on nuclear medicine imaging performed just after CT ...
Rausch I I Ivo Rausch, Centre for medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, Vienna, Austria, Tel. +43/1/404 005 54 50, Fax +43/1/4040 03 98 89 E-mail: - - 2014
Aim: To gather information on clinical operations, quality control (QC) standards and adoption of guidelines for FDG-PET/CT imaging in Austrian PET/CT centres. Methods: A written survey composed of 68 questions related to A) PET/CT centre and installation, B) standard protocol parameters for FDG-PET/CT imaging of oncology patients, and C) standard ...
Leitner Lorenz - - 2014
The control of the lower urinary tract is a complex, multilevel process involving both the peripheral and central nervous system. Due to lesions of the neuraxis, most spinal cord injury patients suffer from neurogenic lower urinary tract dysfunction, which may jeopardise upper urinary tract function and has a negative impact ...
Bracht T T Cardiff University Brain Research Imaging Centre (CUBRIC), School of Psychology,Cardiff - - 2014
Background. The medial forebrain bundle (MFB) is an important pathway of the reward system. Two branches have been described using diffusion magnetic resonance imaging (MRI)-based tractography: the infero-medial MFB (imMFB) and the supero-lateral MFB (slMFB). Previous studies point to white-matter microstructural alterations of the slMFB in major depressive disorder (MDD) ...
Lovati Arianna B AB Cell and Tissue Engineering Laboratory, Hand Surgery Unit, IRCCS Galeazzi Orthopaedic Institute, Cell and Tissue Engineering Laboratory, Gruppo Ospedaliero San Donato Foundation and Mouse and Animal Pathology Laboratory (MAP Lab), Filarete Foundation, Milan, - - 2014
The aims of this study were to determine whether micro-CT is a reliable investigation method to evaluate the severity of OA in the trapezium and to develop a novel micro-CT scoring system based on a quantitative assessment of the subchondral bone thickness in order to better assess OA through an ...
Liao Wei-Chih WC Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC; Division of Gastroenterology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Taipei Municipal Gan-Dau Hospital, Taipei, Taiwan, - - 2014
Lupus mesenteric enteritis is an uncommon condition in systemic lupus erythematosus (SLE) patients with acute abdominal pain. We describe a 28-year-old woman with a 3-day history of watery diarrhea and intermittent vomiting. Abdominal ultrasonography revealed thickening of the intestinal wall and edema with the lumen filled with fluid in this ...
Junker Daniel D Department of Radiology, Medical University Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria, - - 2014
Evaluation of the Prostate Imaging Reporting and Data System (PI-RADS) scoring system for classifying multi-parametric magnetic resonance imaging findings of the prostate using whole-mount step-section slides as reference standard. Prospective inclusion of 50 consecutive patients with biopsy-proven prostate cancer (PCa). All patients received a multi-parametric MRI of the prostate, consisting ...
Yağci Ramazan R Department of Ophthalmology (R.Y., S.A.), Pamukkale University Medical School, Denizli, Turkey; Department of Ophthalmology (E.G.), Erciş State Hospital, Van, Turkey; Department of Ophthalmology (B.F.G.), Turgut Ozal University Medical School, Ankara, Turkey; Department of Ophthalmology (F.U.), Trabzon Arakli Bayram Halil Devlet Hastanesi, Trabzon, Turkey; and Department of Ophthalmology (I.F.H.), Gazi University Medical School, Ankara, - - 2014
To quantify the difference between anterior chamber parameters determined by the Galilei dual Scheimpflug analyzer after uneventful cataract surgery in normotensive eyes. In this study, 39 eyes of 30 patients (11 men and 19 women) who had uneventful cataract surgery with phacoemulsification were evaluated preoperatively, and at 1 month postoperatively ...
Goß Karin K 1. Physikalisches Institut, Universität Stuttgart, Pfaffenwaldring 57, D-70550, Stuttgart, Germany. - - 2014
Molecular magnetism is considered an area where magnetic phenomena that are usually difficult to demonstrate can emerge with particular clarity. Over the years, however, less understandable systems have appeared in the literature of molecular magnetic materials, in some cases showing features that hint at the spontaneous emergence of global structures ...
Tseng Jing-Ren JR Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan, - - 2014
We report two unusual cases of suppurative meningomyelitis and ventriculitis which were successfully detected by FDG PET/CT. The extent of disease and response to treatment were well-delineated. Our data suggest that FDG PET/CT may be clinically useful in patients with rare infections of the central nervous system.
Calamante Fernando F Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, - - 2014
This article is intended to provide guidelines for the minimum level of safety and operational knowledge that an MR system operator should exhibit in order to safely perform an MR procedure in a human subject in a research setting. This article represents the position of the International Society for Magnetic ...
Plunk Matthew R MR Department of Radiology, University of Washington School of Medicine, Seattle, - - 2014
Congenital malformations detected in any fetal system using ultrasound may be further evaluated with magnetic resonance imaging (MRI) to improve counseling, to plan deliveries appropriately, and sometimes to enable fetal interventions. In this first half of a 2-part review, the history and safety factors regarding fetal MRI, as well as ...
Julià-Sapé Margarida M Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Cerdanyola del Vallès, Spain; Departament de Bioquímica i Biologia Molecular, Unitat de Bioquímica de Biociències, Edifici Cs, Universitat Autònoma de Barcelona, UAB, Cerdanyola del Vallès, Spain; Institut de Biotecnologia i de Biomedicina (IBB), Universitat Autònoma de Barcelona, UAB, Cerdanyola del Vallès, - - 2014
In a previous study, we have shown the added value of (1) H MRS for the neuroradiological characterisation of adult human brain tumours. In that study, several methods of MRS analysis were used, and a software program, the International Network for Pattern Recognition of Tumours Using Magnetic Resonance Decision Support ...
Nakazawa Hisato H Department of Radiological Sciences, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan Nagoya Radiosurgery Center, Nagoya Kyoritsu Hospital, Nagoya, Aichi, Japan - - 2014
We assessed the geometric distortion of 1.5-Tesla (T) and 3.0-T magnetic resonance (MR) images with the Leksell skull frame system using three types of cranial quick fixation screws (QFSs) of different materials-aluminum, aluminum with tungsten tip, and titanium-for skull frame fixation. Two kinds of acrylic phantoms were placed on a ...
Liu NingFei N Department of Plastic and Reconstructive Surgery, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, - - 2014
Background Imaging of the lymphatic system is difficult because of its structural and anatomical characteristics, and the conventional diagnostic method, radionuclide-based imaging, has the disadvantage of poor resolution. Magnetic resonance (MR) imaging has been shown the capability of depicting lymphatic channels in lymphedema recently. The purpose of this study was to ...
Hirsch Karen G KG Stanford Neurocritical Care Program, Stanford Stroke Center, Stanford University Medical Center, Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, - - 2014
To develop a qualitative brain magnetic resonance imaging (MRI) scoring system for comatose cardiac arrest patients that can be used in clinical practice. Consecutive comatose postcardiac arrest patients were prospectively enrolled. Routine MR brain sequences were scored by two independent blinded experts. Predefined brain regions were qualitatively scored on the ...
Bonfiglioli R - - 2014
Alterations of the cardiac autonomic nervous system play an important role in the pathway of many heart diseases. Nuclear imaging tools have been demonstrated to be useful for global and regional assessment of myocardial innervation. We used 11C-meta-hydroxy-ephedrine (11C-mHED), a catecholamine analogue, as a radiotracer usable with a PET/CT scanner ...
Mitchell Donald G DG Thomas Jefferson University, Philadelphia, - - 2014
To improve standardization and consensus regarding performance, interpreting and reporting CT and MRI examinations of the liver in patients at risk for hepatocellular carcinoma (HCC), LI-RADS (Liver Imaging Reporting and Data System) was launched in March, 2011, and adopted by many clinical practices throughout the world. LI-RADS categorizes nodules recognized ...
Seilmayer Martin M Helmholtz-Zentrum Dresden-Rossendorf, P.O. Box 510119, D-01314 Dresden, - - 2014
The azimuthal version of the magnetorotational instability (MRI) is a nonaxisymmetric instability of a hydrodynamically stable differentially rotating flow under the influence of a purely or predominantly azimuthal magnetic field. It may be of considerable importance for destabilizing accretion disks, and plays a central role in the concept of the ...
Kok A C AC Department of Orthopedic Surgery, Orthopedic Research Center Amsterdam, Academic Medical Center Amsterdam, Amsterdam, The Netherlands. Electronic address: - - 2014
Talar osteochondral defects (OCDs) are imaged using magnetic resonance imaging (MRI) or computed tomography (CT). For extensive follow-up, ultrasound might be a fast, non-invasive alternative that images both bone and cartilage. In this study the potential of ultrasound, as compared with CT, in the imaging and grading of OCDs is ...
Zikou Anastasia K AK Department of Radiology, Medical School, University of Ioannina, Ioannina, - - 2014
To investigate structural brain changes in inflammatory bowel disease (IBD). Brain magnetic resonance imaging (MRI) was performed on 18 IBD patients (aged 45.16 ± 14.71 years) and 20 aged-matched control subjects. The imaging protocol consisted of a sagittal-FLAIR, a T1-weighted high-resolution three-dimensional spoiled gradient-echo sequence, and a multisession spin-echo echo-planar diffusion-weighted sequence. Differences ...
Weiss M M Mayo Weiss MD, Department of Nuclear Medicine, Ludwig-Maximilians-University of Munich, Marchioninistr.15, 81377 Muenchen, Germany, Tel. +49/(0)89/70 95 76 38, E-mail: - - 2014
Purpose: To compare the diagnostic accuracy of magnetic resonance imaging (MR-lymphangiography) and lymphoscintigraphy for assessment of focal lesions of the peripheral lymphatic system. Patients with focal lymphatic transport disorders might benefit from surgi-cal interventions. Patients, methods: We examined by lymphoscintigraphy and MR-lymphangiography a total of 85 lower limbs in 46 ...
Zibly Zion Z Department of Neurological Surgery, The Charles Clore Hospitalization Tower, West Wing Sheba Medical Center, Ramat Gan, Israel. Electronic address: - - 2014
Stereotaxic sonoablative surgery by MRI guided high intensity focused ultrasound (FUS) holds great potential in disorders of the central nervous system (CNS). We previously described the ExAblate 2000 system (InSightec, Tirat Carmel, Israel), currently in use for various pathologies including uterine, liver, and, breast tumors, and referred to as the ...
Brea Álvarez B B Radiodiagnóstico. Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, España. Electronic address: - - 2014
Perineural spread is the dissemination of some types of head and neck tumors along nervous structures. Perineural spread has negative repercussions on treatment because it requires more extensive resection and larger fields of irradiation. Moreover, perineural spread is associated with increased local recurrence, and it is considered an independent indicator ...
Yang Z Z From the Department of Neurosurgery (Z.Y., B.H., Z.J., J.C., Y.Z., Y.F., J.L.), Changhai Hospital, Second Military Medical University, Shanghai, China; and Siemens Ltd. China (J.G., J.H., J.B.), Healthcare Sector, Angiography & Interventional X-ray - - 2014
The intracerebral hemorrhage drainage through minimally invasive approach is emerging as an alternative for traditional craniotomy, due to its improved survival rate and reduced complication rate. In this study, we investigated the feasibility and safety of a flat detector CT-based puncture planning and navigation system for minimally invasive hematoma drainage ...
Ioannidis Panagiotis P 2nd Department of Neurology, AHEPA University Hospital, Thessaloniki St. Kyriakidi 1, 54636, Thessaloniki, Greece, - - 2014
Concomitant central nervous system (CNS) involvement in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is rare. Although the spinal nerve roots may present MRI abnormalities in CIDP, hitherto, the spinal cord has been investigated in a single study. We retrospectively investigated clinically and with MRI a cohort of patients with definite CIDP ...
Joly Olivier O Institute of Neuroscience, Newcastle University, Newcastle, NE2 4HH, UK, - - 2014
Idiopathic scoliosis (IS) is a frequent 3D structural deformity of the spine with a multi-factorial aetiology which remains largely unclear. In the last decade, human magnetic resonance imaging (MRI) morphometry studies (e.g. cortical thickness, 2D shape of the corpus callosum) have aimed to investigate the potential contribution of the central ...
Sarica Ozgur O From the Department of Radiology, Taksim Education and Research Hospital, Istanbul, - - 2014
This study aims to evaluate the strength of magnetic resonance (MR) lesion descriptors for malignancy and to determine the effectiveness of a scoring system that combines BI-RADS parameters with additional criteria. Three hundred thirty-nine histopathologically proven lesions that had undergone MR imaging were analyzed retrospectively. Based on the Fischer scoring ...
Yam Benjamin L BL Department of Radiology, Hospital of the University of Pennsylvania, Perelman School of Medicine at the University of Pennsylvania, 34th and Spruce Streets, Philadelphia, PA 19104-4283, - - 2014
Although ultrasound, computed tomography, and cholescintigraphy play essential roles in the evaluation of suspected biliary abnormalities, magnetic resonance (MR) imaging and MR cholangiopancreatography can be used to evaluate inconclusive findings and provide a comprehensive noninvasive assessment of the biliary tract and gallbladder. This article reviews standard MR and MR cholangiopancreatography ...
Fallone Biagio Gino BG Cross Cancer Institute, University of Alberta, Edmonton, Alberta, Canada. Electronic address: - - 2014
We have successfully built linac-magnetic resonance imaging (MR) systems based on a linac waveguide placed between open MR planes (perpendicular) or through the central opening of one of the planes (parallel) to improve dosimetric properties. It rotates on a gantry to irradiate at any angle. Irradiation during MR imaging and ...
Mutic Sasa S Department of Radiation Oncology, Washington University School of Medicine, St. Louis, MO. Electronic address: - - 2014
A description of the first commercially available magnetic resonance imaging (MRI)-guided radiation therapy (RT) system is provided. The system consists of a split 0.35-T MR scanner straddling 3 (60)Co heads mounted on a ring gantry, each head equipped with independent doubly focused multileaf collimators. The MR and RT systems share ...
Jaffray David A DA Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada; Techna Institute, University Health Network, Toronto, Ontario, Canada. Electronic address: - - 2014
Magnetic resonance (MR) imaging is routinely employed in the design of radiotherapy (RT) treatment plans for many disease sites. It is evident that tighter integration of MR imaging into the RT process would increase confidence in dose placement and facilitate the integration of new MR imaging information (including anatomical and ...
Liney Gary P GP Ingham Institute for Applied Medical Research, Liverpool, Sydney, New South Wales, Australia; Department of Medical Physics, University of Wollongong, Wollongong, New South Wales, Australia. Electronic address: - - 2014
Magnetic resonance imaging (MRI) has a number of benefits for the planning of radiotherapy (RT), but its uptake into clinical practice has often been restricted to specialist research sites. There is often a lack of detailed MRI knowledge within the RT community and an apprehension of geometric distortions, both of ...
Jha Reena C RC 1 Department of Radiology, Medstar Georgetown University Hospital, 3800 Reservoir Rd, NW, Washington, DC - - 2014
OBJECTIVE. The purpose of this article is to review the imaging features and Liver Imaging Reporting and Data System (LI-RADS) categorization of benign and likely benign entities, including typical cirrhotic nodules, distinctive nodular observations, and benign entities that may simulate hepatocellular carcinoma. CONCLUSION. LI-RADS is a system of standardized criteria ...
Fiorella David D Department of Neurological Surgery, Stony Brook University Medical Center, Stony Brook, New York, - - 2014
The Apollo system (Penumbra Inc, Alameda, California, USA) is a low profile irrigation-aspiration system designed for the evacuation of intracranial hemorrhage. To demonstrate the feasibility of using Apollo in combination with cone beam CT guidance. Parenchymal (n=1) and mixed parenchymal-intraventricular hematomas (n=1) were created in cadaver heads using a transvascular ...
Lim Hyun Kyong HK Department of Radiology, Seoul National University College of Medicine, Seoul 110-744, Korea. ; Department of Radiology, SMG-SNU Boramae Medical Center, Seoul 156-707, - - 2014
To investigate the interobserver reproducibility and diagnostic feasibility of a visual grading system for assessing atrophy of the supraspinatus muscle on magnetic resonance imaging (MRI). Three independent radiologists retrospectively evaluated the occupying ratio of the supraspinatus muscle in the supraspinatus fossa on 192 shoulder MRI examinations in 188 patients using ...
Suh Hee Jung HJ Cancer Prevention & Detection Center, National Cancer Center, Goyang 410-769, - - 2014
Magnetic resonance imaging (MRI) of the breast is used for various indications. Contrary to computed tomography as a staging tool, breast MRI focuses on the breast parenchyma and axilla. In spite of narrow field of view, many structures such as the anterior portion of the lungs, mediastinum, bony structures and ...
Kartal Aslı Gülfer AG The Department of Emergency Medicine, Faculty of Medicine, Kocaeli University, Kocaeli, - - 2014
Vertigo is a common presenting complaint resulting from central or peripheral etiologies. Because central causes may be life-threatening, ascertaining the nature of the vertigo is crucial in the emergency department (ED). With a broad range of potential etiologies, distinguishing central causes from benign peripheral causes is a diagnostic challenge. Cranial ...
Schimmöller Lars L Department of Diagnostic and Interventional Radiology, University Dusseldorf, Medical Faculty, Moorenstr. 5, 40225, Dusseldorf, Germany, - - 2014
This study evaluated the accuracy of MR sequences [T2-, diffusion-weighted, and dynamic contrast-enhanced (T2WI, DWI, and DCE) imaging] at 3T, based on the European Society of Urogenital Radiology (ESUR) scoring system [Prostate Imaging Reporting and Data System (PI-RADS)] using MR-guided in-bore prostate biopsies as reference standard. In 235 consecutive patients ...
Tanaka Toshihiro T Department of Radiology, Nara Medical University, Kashihara, - - 2014
Hybrid CT/angiography (angio) system and C-arm cone-beam CT provide cross-sectional imaging as an adjunct to angiography. Current interventional oncologic procedures can be conducted precisely using these two technologies. In this article, several cases using a hybrid CT/angio system are shown first, and then the advantages and disadvantages of the hybrid ...
Arealis Georgios G Orthopedic Department, Queen's Hospital, Burton on Trent, UK. Electronic address: - - 2014
Distal radius fractures are very common upper limb injuries irrespective of the patient's age. The aim of our study is to evaluate the reliability of the three systems that are often used for their classification (AO - Arbeitsgemeinschaft für Osteosynthesefragen/Association for the Study of Internal Fixation, Fernandez and Universal) and ...
van den Berg Rosaline R Department of Rheumatology, Leiden University Medical Center, Leiden, The - - 2014
Investigating changes in patient classification (ASAS (Assessment of SpondyloArthritis international Society) axSpA criteria) based on evaluation of images of the sacro-iliac joints (MRI-SI and X-SI) by local and central readers. The DESIR cohort included patients with inflammatory back pain (IBP; ≥3 months, but <3 years), suggestive of axSpA. Local radiologists/rheumatologists (local-reading) and ...
Bentley R T RT Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, IN, - - 2014
The primary study objective was to determine whether clinical examination and magnetic resonance imaging (MRI) can underestimate canine gliomatosis cerebri (GC); we also investigated immunohistochemical features. Seven dogs with GC were studied; four recruited specifically because of minimal MRI changes. Neuroanatomic localization and the distribution of MRI, gross and sub-gross ...
Nowak J J From the Reference Center for Neuroradiology (J.N., C.S., F.B., M.W.-M.), University Hospital of Würzburg, Würzburg, Germany; Department of Radiology, Pathology Research (C.S.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Department of Radiology and Neuroradiology (F.B.), University of Witten/Herdecke, Cologne-Merheim Medical Center, Cologne, Germany; Department of Neuropathology (T.P.), Brain Tumor Reference Center, Bonn, Germany; and Department of Pediatric Hematology and Oncology (C.F., K.v.H., S.R.), University Medical Center Hamburg-Eppendorf, Hamburg, Germany. - - 2014
Ependymoblastoma is a malignant embryonal tumor that develops in early childhood and has a dismal prognosis. Categorized by the World Health Organization as a subgroup of CNS-primitive neuroectodermal tumor, ependymoblastoma is histologically defined by "ependymoblastic rosettes." Because it is so rare, little is known about specific MR imaging characteristics of ...
Ginsburg Shoshana B SB Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, - - 2014
To identify computer-extracted features for central gland and peripheral zone prostate cancer localization on multiparametric magnetic resonance imaging (MRI). Preoperative T2-weighted (T2w), diffusion-weighted imaging (DWI), and dynamic contrast-enhanced (DCE) MRI were acquired from 23 men with confirmed prostate cancer. Following radical prostatectomy, the cancer extent was delineated by a pathologist ...
Ho Chi Long CL Department of Diagnostic Radiology, Singapore General Hospital, 4 Outram Road, Singapore 169608. Electronic address: - - 2014
The purpose of our study is to differentiate primary central nervous system lymphoma (PCNSL) from high-grade glioma (HGG) using perfusion-weighted imaging (PWI) and magnetic resonance spectroscopy (MRS). We retrospectively reviewed 30 patients who underwent PWI and MRS at short and intermediate echo time (TE), and subsequently classified into PCNSL and ...
Riva Nilo N From the Neuropathology Unit, Institute of Experimental Neurology (NR, LC, TD, GD, FC, GC, AQ) and Division of Neuroscience (NR, LC, DU, FB, FC, PP, UDC, GC, AQ), IRCCS San Raffaele Scientific Institute; Laboratory of Molecular Neurobiology, Department of Neuroscience, IRCCS Istituto di Ricerche Farmacologiche Mario Negri (MP, GS, CB); Department of Neurorehabilitation Sciences, Casa Cura Policlinico (MC); and Vita e Salute San Raffaele University (GC), Milan, - - 2014
Growing evidence indicates that alterations within the peripheral nervous system (PNS) are involved at an early stage in the amyotrophic lateral sclerosis (ALS) pathogenetic cascade. In this study, magnetic resonance imaging (MRI), neurophysiologic analyses, and histologic analyses were used to monitor the extent of PNS damage in the hSOD-1 ALS ...
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