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Roosenburg S S Department of Radiology and Nuclear Medicine, Radboud University Medical Center , 6500 HB Nijmegen, The - - 2014
Cholecystokinin-2 (CCK-2) receptors, overexpressed in cancer types such as small cell lung cancers (SCLC) and medullary thyroid carcinomas (MTC), may serve as targets for peptide receptor radionuclide imaging. A variety of CCK and gastrin analogues has been developed, but a major drawback is metabolic instability or high kidney uptake. The ...
Hynes S L SL Division of Plastic and Reconstructive Surgery, The Hospital for Sick Children, Toronto, Ontario, - - 2014
We describe the CT angiography protocol and surgical technique utilized at our institution for single-stage release of adjacent web-spaces in non-Apert syndactyly. In a series of seven consecutive hands we analyse syndactyly anatomy, CT angiographic findings, operative details, and complications. Outcomes were assessed with a functional activity evaluation, range of ...
Verburg Frederik A FA From the *Department of Nuclear Medicine, RWTH Aachen University Hospital, Aachen, Germany; †Department of Nuclear Medicine, Maastricht University Medical Center, Maastricht, The Netherlands; ‡Department of Pathology, University Hospital Düsseldorf, Düsseldorf, Germany; and §Department of Endocrinology, RWTH Aachen University Hospital, Aachen, - - 2014
A 51-year-old man with a history of metastatic medullary thyroid cancer (MTC) presented with high adrenocorticotropin (ACTH) and urinary free cortisol levels. The diagnosis of ectopic ACTH production, a rare MTC complication, was established in this patient. PET/CT using the somatostatin analogue DOTA-(Tyr)-octreotate labeled with gallium (Ga-DOTATATE) was performed, showing ...
Lococo Filippo F Unit of Thoracic Surgery, IRCCS-Arcispedale Santa Maria Nuova, Reggio Emilia, Italy . - - 2014
Bronchial carcinoids (BC) are rare well-differentiated neuroendocrine tumours (NET) sub-classified into typical (TC) and atypical carcinoids (AC). A correct pathological identification in the pre-operative setting is a key element for planning the best strategy of care, considering the different biological behavior of TC and AC. Controversial results have been reported ...
Sharma Punit P Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, - - 2014
Neuroendocrine tumors (NETs) are rare neoplasms characterized by overexpression of somatostatin receptors (SSTRs). Functional imaging plays a crucial role in management of NETs. Recently, positron emission tomography/computed tomography (PET/CT) with (68)Gallium ((68)Ga)-labeled somatostatin analogues has shown excellent results for imaging of NETs and better results than conventional SSTR scintigraphy. In ...
Berkolaiko Gregory G Department of Mathematics, Texas A&M University, , College Station, TX 77843-3368, - - 2014
We prove an analogue of the magnetic nodal theorem on quantum graphs: the number of zeros of the nth eigenfunction of the Schrödinger operator on a quantum graph is related to the stability of the nth eigenvalue of the perturbation of the operator by magnetic potential. More precisely, we consider ...
Wehner Tim T Department of Clinical Neurophysiology, National Hospital for Neurology and Neurosurgery, London, United Kingdom; Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College of London, London, United - - 2013
Functional imaging studies complement structural magnetic resonance imaging (MRI) in the assessment of patients with brain tumor-associated focal epilepsy. (11) C-Methionine (MET) and (18) F-fluoro-ethyl-l-tyrosine (FET) are amino acid analogues that highlight metabolically active areas in positron emission tomography (PET). Ictal single photon emission computed tomography (SPECT) can provide information ...
Schuster David M - - 2013
We prospectively evaluated the amino acid analogue PET radiotracer anti-1-amino-3-[(18)F]fluorocyclobutane-1-carboxylic acid (anti-3-[(18)F]FACBC) compared to (111)In-capromab-pendetide SPECT-CT in the detection of recurrent prostate carcinoma. 93 patients met inclusion criteria for this analysis who underwent both anti-3-[(18)F]FACBC PET-CT and (111)In-capromab-pendetide SPECT-CT for suspected recurrent prostate carcinoma within 90 days. Reference standards were ...
Panagiotidis Emmanouil E Institute of Nuclear Medicine, University College London Hospitals NHS Trust, London, - - 2014
The most widely used PET radiopharmaceutical in daily clinical practice is (18)F-fluorodeoxyglucose (FDG). The evaluation of glycolytic metabolism by (18)F-FDG is potentially useful in identifying high-risk patients with aggressive neuroendocrine disease associated with a poor outcome. Although the use of new somatostatin analogues labeled with 68-Gallium for PET has significantly ...
Skoura Evangelia E Nuclear Medicine Department, Evangelismos Hospital, Athens, - - 2013
Inherited and sporadic medullary thyroid cancer (MTC) is an uncommon and medically challenging malignancy. Even if the extent of initial surgery is deemed adequate, the recurrence rate remains high, up to 50% in most series. Measurement of serum calcitonin is important in the follow-up of patients with MTC, and reliably ...
Coronado Eugenio - - 2013
The magnetoresistance (MR) effect of thin films of the Prussian Blue Analogue (PBA) Cr5.5(CN)12·11.5H2O, prepared by electrochemical deposition, has been measured using the standard two-point probe method. This molecule-based ferrimagnetic material, with a Tc = 240 K, exhibits MR up to 2% at 6 T and 200 K.
Goizueta-Adame Carlos C - - 2013
The study describes the arthoscopic use of resorbable pins for the internal derangement of the temporomandibular joint with McCain's technique. Clinical and image features are reported retrospectively. Twenty-seven consecutive patients (34 joints) were included. Symptomatic internal derangement and anterior-medial disc displacement with or without reduction in magnetic resonance images (MRI) ...
Kim Sang Woo - - 2013
To suggest a new useful diagnostic technique, principles of the selective excitation technique-magnetic resonance images (Proset-MRI), and to know the precise radiologic findings that can prove symptomatic foraminal and extraforaminal stenosis at L5-S1. Nineteen patients with symptomatic L5-S1 stenosis were checked by Proset-MRI. Four patients were performed decompressive surgery and ...
Lee J-S - - 2013
A number of recent transport and magnetization studies have shown signs of ferromagnetism in the LaAlO3/SrTiO3 heterostructure, an unexpected property with no bulk analogue in the constituent materials. However, no experiment thus far has provided direct information on the host of the magnetism. Here we report spectroscopic investigations of the ...
Law W Phillip - - 2013
Gallium-68 ((68) Ga)-labelled somatostatin analogue imaging by positron emission tomography (PET) is increasingly replacing single photon (such as (111) In-labelled octreotide) imaging in the detection and staging of carcinoid and other neuroendocrine tumours. Among other tissues, pituitary uptake of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-octreotate (DOTA-TATE) and other somatostatin analogues is physiological. DOTA-TATE also ...
Scott Julia A - - 2012
To date, growth of the human fetal cerebellum has been estimated primarily from linear measurements from ultrasound and 2D magnetic resonance imaging (MRI). In this study, we use 3D analytical methods to develop normative growth trajectories for the cerebellum in utero. We measured cerebellar volume, linear dimensions, and local surface ...
Beatty Brian Lee - - 2012
Modern manatees have a unique type of tooth development, continually forming identical new molars in the posterior end of each quadrant of their mouths, and then progressively moving teeth anteriorly, only to reabsorb roots and spit out worn crowns. This process is not only developmentally complex, but requires space in ...
Erickson Laura C - - 2012
We piloted a suite of approaches aimed to facilitate a successful series of up to four brain and muscle (31)Phosphorus-Magnetic Resonance Spectroscopy ((31)P-MRS) scans performed in one session in 12 awake, non-sedated subjects (ages 6-18), 6 with autism spectrum disorders (ASD) and 6 controls. We targeted advanced preparation, parental input, ...
Brustad Eric M - - 2012
New tools that allow dynamic visualization of molecular neural events are important for studying the basis of brain activity and disease. Sensors that permit ligand-sensitive magnetic resonance imaging (MRI) are useful reagents due to the noninvasive nature and good temporal and spatial resolution of MR methods. Paramagnetic metalloproteins can be ...
Yu Jian-Xin - - 2012
There is increasing interest in the development of reporter agents to reveal enzyme activity in vivo using small animal imaging. We have previously demonstrated the feasibility of detecting lacZ gene activity using the commercially available 3,4-cyclohexenoesculetin-β-D-galactopyranoside (S-Gal™) as a (1)H MRI reporter. Specifically, β-galactosidase (β-gal) releases the aglycone, which forms ...
Tessler Franklin N - - 2012
Our goal was to investigate the effect of displayed image magnification on perception of the size of hepatic lesions on abdominal computed tomography (CT) scans. Institutional review board approval and informed observer consent were obtained. Three experienced radiologists reviewed 90 CT image pairs in one session. Each image pair demonstrated ...
Jones M - - 2012
This paper presents the design of the 'Tree Hugger', an open access, transportable, 1.1MHz (1)H nuclear magnetic resonance imaging system for the in situ analysis of living trees in the forest. A unique construction employing NdFeB blocks embedded in a reinforced carbon fibre frame is used to achieve access up ...
Ebrahimi Behzad - - 2012
Functional blood oxygenation level-dependent (BOLD) magnetic resonance imaging is a powerful tool to assess renal function, but BOLD analysis using T2* image differentiation of cortex and medulla is laborious and prone to errors. We developed and validated an alternative compartmental analysis method to differentiate renal cortical and medullary BOLD relaxivity ...
Jung Brian C BC Department of Neurology, The Johns Hopkins University, School of Medicine, Baltimore, MD 21287, - - 2012
In this study, we used manual delineation of high-resolution magnetic resonance imaging (MRI) to determine the spatial and temporal characteristics of the cerebellar atrophy in spinocerebellar ataxia type 2 (SCA2). Ten subjects with SCA2 were compared to ten controls. The volume of the pons, the total cerebellum, and the individual ...
Kao Hung-Wen - - 2012
OBJECTIVES: To investigate the ability of susceptibility-weighted imaging (SWI) to predict stroke evolution in comparison with perfusion-weighted imaging (PWI). METHODS: In a retrospective analysis of 15 patients with non-lacunar ischaemic stroke studied no later than 24 h after symptom onset, we used the Alberta Stroke Program Early CT Score (ASPECTS) to ...
Evans Benjamin A - - 2012
Magnetic elastomers have been widely pursued for sensing and actuation applications. Silicone-based magnetic elastomers have a number of advantages over other materials such as hydrogels, but aggregation of magnetic nanoparticles within silicones is difficult to prevent. Aggregation inherently limits the minimum size of fabricated structures and leads to non-uniform response ...
Dʼsouza Maria Mathew - - 2012
A 58-year-old woman with breast carcinoma, after mastectomy, radiotherapy, and chemotherapy, underwent a whole-body F-18 FDG PET/CT for restaging, which revealed multiple skeletal metastasis. Hypometabolism was noted in the right frontal lobe. The patient subsequently underwent a C-11 methionine brain scan, which demonstrated multiple dural-based metastatic foci confirmed on contrast-enhanced ...
Moon Sung Gyu - - 2012
The purposes of this study were to assess chronologic changes in normal growth plate after radiofrequency-induced thermal injury and to evaluate the feasibility of MRI for revealing alteration of the growth plate. Radiofrequency ablation was performed on the right proximal tibia of 13 8-week-old New Zealand White rabbits. An 18-gauge ...
Kósa Gábor G School of Mechanical Engineering, Faculty of Engineering, Tel Aviv University, Tel Aviv, Israel. - - 2012
Capsule endoscopy is a promising technique for diagnosing diseases in the digestive system. Here we design and characterize a miniature swimming mechanism that uses the magnetic fields of the MRI for both propulsion and wireless powering of the capsule. Our method uses both the static and the radio frequency (RF) ...
Nakano Sachiko - - 2012
PURPOSE: To evaluate the findings of hepatic metastases from malignant pheochromocytoma/paraganglioma on non-contrast-enhanced and contrast-enhanced ultrasonography (US) and compare them with other imaging modalities. SUBJECTS AND METHODS: US was performed on eight patients with 65 hepatic metastases. Non-contrast computed tomography (CT), meta-iodo-benzyl-guanidine scintigraphy ((123)I-MIBG), and fluorine-18-fluorodeoxyglucose positron emission tomography (FDG-PET) ...
Saliba Issam - - 2012
OBJECTIVE: To assess the correlation between the enlarged vestibular aqueduct (EVA) diameter and (1) the hearing loss level (mild, moderate, severe and profound and (2) the hearing evolution. The secondary objective was to obtain measurement limits on the coronal plane of the temporal bone CT scan for the diagnosis of ...
Zhang Shuo - - 2012
PURPOSE: To evaluate the use of a novel real-time magnetic resonance imaging (MRI) technique for the assessment of normal swallowing dynamics. MATERIALS AND METHODS: In a cohort of 10 healthy subjects, real-time MRI movies at 24.3 frames per second were obtained in sagittal, coronal, and axial orientation during self-controlled swallows ...
Cai Kejia K Center for Magnetic Resonance and Optical Imaging, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, - - 2012
Glutamate, a major neurotransmitter in the brain, shows a pH- and concentration-dependent chemical exchange saturation transfer effect (GluCEST) between its amine group and bulk water, with potential for in vivo imaging by nuclear magnetic resonance. GluCEST asymmetry is observed ∼3 p.p.m. downfield from bulk water. Middle cerebral artery occlusion in ...
Bagepally Bhavani Shankara - - 2012
Introduction: Apolipoprotein E4 (ApoE ε4) polymorphism is a known genetic risk factor for Alzheimer's disease (AD). Objectives: To evaluate the role of ApoE ε4 on white matter structural integrity in AD. Methods: Subjects were 32 patients with probable AD (ApoE ε4-positive: n = 15) and 18 matched controls (ApoE ε4-positive: ...
Korkusuz Huedayi - - 2012
PURPOSE: To evaluate hyperintense Gd-DTPA- compared with hyper- and hypointense Gd-EOB-DTPA-enhanced magnet resonance imaging (MRI) in c-myc/TGFα transgenic mice for detecting hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Twenty HCC-bearing transgenic mice with overexpression of the protooncogene c-myc and transforming growth factor-alpha (TGF-α) were analyzed. MRI was performed using a 3-T ...
Tuite Paul J PJ Department of Neurology, University of Minnesota, MMC 295, 420 Delaware St SE, Minneapolis, MN 55455, USA. - - 2012
In addition to classic midbrain pathology, Parkinson's disease (PD) is accompanied by changes in pontine and medullary brainstem structures. These additional abnormalities may underlie non-motor features as well as play a role in motor disability. Methods: Using novel magnetic resonance imaging (MRI) methods based on rotating frame adiabatic R(1ρ) (i.e., ...
Swarte Renate M C - - 2012
OBJECTIVE: (a) To relate MRI patterns of brain injury to somatosensory evoked potentials (SEPs), and (b) to determine the prognostic value of SEPs in addition to continuous EEG monitoring (cEEG) and cerebral imaging, in term asphyxiated newborns. METHODS: Fifty one consecutive neonates were studied. Survivors were followed for at least ...
Amato M P - - 2012
OBJECTIVE:To evaluate cognitive changes in a cohort of radiologically isolated syndromes (RIS) suggestive of multiple sclerosis (MS) and to assess their relationship with quantitative magnetic resonance (MR) measures such as white matter (WM), lesion loads, and cerebral atrophy. METHODS:We assessed the cognitive performance in a group of 29 subjects with ...
Camus V - - 2012
Positron emission tomography (PET) imaging of brain amyloid load has been suggested as a core biomarker for Alzheimer's disease (AD). The aim of this study was to test the feasibility of using PET imaging with (18)F-AV-45 (florbetapir) in a routine clinical environment to differentiate between patients with mild to moderate ...
Henriksen Otto M - - 2012
PURPOSE: To investigate the within and between subject variability of quantitative cerebral blood flow (CBF) measurements in normal subjects using various MRI techniques and positron emission tomography (PET). MATERIALS AND METHODS: Repeated CBF measurements were performed in 17 healthy, young subjects using three different MRI techniques: arterial spin labeling (ASL), ...
Auboiroux Vincent - - 2012
MR acoustic radiation force imaging (ARFI) is an elegant adjunct to MR-guided high intensity focused ultrasound for treatment planning and optimization, permitting in situ assessment of the focusing and targeting quality. The thermal effect of high intensity focused ultrasound pulses associated with ARFI measurements is recommended to be monitored on ...
Zhou Anqi - - 2012
PURPOSE: To systematically evaluate and compare the performance of water-saturated and nonwater-saturated T1-weighted 3.0 T magnetic resonance imaging (MRI) in the application of visceral adipose tissue (VAT) quantification. MATERIALS AND METHODS: Forty-five patients underwent abdomen MRI using two different sequences at 3.0 T: 1) a traditional T1-weighted gradient echo sequence, ...
Chiba Yasuyoshi - - 2012
Object Immunotherapy targeting the Wilms tumor 1 (WT1) gene product is a promising treatment modality for patients with malignant gliomas, and there have been reports of encouraging results. It has become clear, however, that Gd-enhanced MR imaging does not reflect prognosis, thereby necessitating a more robust imaging evaluation system for ...
Shrot Shai - - 2012
Organophosphates are highly toxic substances, which cause severe brain damage. The hallmark of the brain injury is major convulsions. The goal of this study was to assess the spatial and temporal MR changes in the brain of paraoxon intoxicated rats. T2-weighted MRI and (1) H-MR-spectroscopy were conducted before intoxication, 3 ...
van den Bogaard S J A - - 2012
BACKGROUND AND PURPOSE:MTI has the potential to detect abnormalities in normal-appearing white and gray matter on conventional MR imaging. Early detection methods and disease progression markers are needed in HD research. Therefore, we investigated MTI parameters and their clinical correlates in premanifest and manifest HD.MATERIALS AND METHODS:From the Leiden TRACK-HD ...
Guo Peng-Hu - - 2012
A toroidal magnetic moment in the absence of a conventional total magnetic moment was first observed in a novel tetranuclear dysprosium cluster with nonmagnetic ground state. The toroidal state is quite robust with respect to variations of the exchange parameters.
Bala Kumar S - - 2012
We model a very large, tunable magnetoresistance (MR) in a graphene nanoribbon field-effect transistor, without artificial engineering of ferromagnetic contacts. A high MR of nearly 100% (about 50%) is obtained at low temperature (room temperature). We show that the MR ratio can be further tuned by using conventional electric field, ...
Lee Byeonghee - - 2012
We report Lorentz force-induced actuation of a silicon microcantilever having an integrated resistive heater. Oscillating current through the cantilever interacts with the magnetic field around a NdFeB permanent magnet and induces a Lorentz force that deflects the cantilever. The same current induces cantilever heating. With AC currents as low as ...
Vandendriessche Stefaan - - 2012
We have measured the magnetization-induced second harmonic generation (MSHG) of a nanocomposite consisting of iron oxide nanoparticles in a polymer film. The existing theoretical framework is extended to include DC magnetic fields in order to characterize the MSHG signal and analyze the measurements. Additionally, magnetic hysteresis loops are measured for ...
Watanabe Masaki - - 2012
Noncontrast computed tomography (NCCT) has been considered the standard test for determining eligibility for thrombolysis from the beginning of the thrombolytic era. CT angiography (CTA) reveals the cranio-cervical vessel and the occlusion site. Furthermore, the source image (SI) of the CTA (CTA-SI) reflects cerebral blood volume and can detect the ...
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