T(2) was used in this study to assess tendon microstructure. Two unloaded digital extensor tendons were bent such that their long axes were imaged throughout 180° with respect to B(0) . T(2) -weighted images reveal periodic banding (∼200 μm) when tendons were oriented at ±55° with respect to B(0) . ...

The upregulation of low-density lipoprotein (LDL) transporters in tumour cells has been exploited to deliver a sufficient amount of gadolinium/boron/ligand (Gd/B/L) probes for neutron capture therapy, a binary chemio-radiotherapy for cancer treatment. The Gd/B/L probe consists of a carborane unit (ten B atoms) bearing an aliphatic chain on one side ...

OBJECTIVE: Bucket-handle tear is a displaced vertical longitudinal tear of the meniscus. Several signs of the tear have been described on MRI but none in the axial plane. We propose to describe such a sign named the V-sign that is seen at the junction of the displaced fragment and the ...

PURPOSE: To evaluate image quality of dose-reduced CT of the paranasal-sinus using an iterative reconstruction technique. METHODS: In this study 80 patients (mean age: 46.9±18 years) underwent CT of the paranasalsinus (Siemens Definition, Forchheim, Germany), with either standard settings (A: 120kV, 60mAs) reconstructed with conventional filtered back projection (FBP) or ...

Systemic thrombolysis rapidly improves right ventricular (RV) dysfunction in patients with acute pulmonary embolism (PE) but is associated with major bleeding complications in up to 20%. The efficacy of low-dose, catheter-directed ultrasound-accelerated thrombolysis (USAT) on the reversal of RV dysfunction is unknown. We performed a retrospective analysis of 24 PE ...

OBJECTIVES:: To evaluate dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters in the prediction of the immediate therapeutic response of MR-guided high-intensity focused ultrasound (HIFU) therapy in the treatment of symptomatic uterine fibroids MATERIALS AND METHODS:: Institutional review board approved this study, and informed consent was obtained from all participants. A ...

The variation of the native T(1) (T(10) ) of different tissues and B(1) transmission-field inhomogeneity at 3 T are major contributors of errors in the quantification of breast dynamic contrast-enhanced MRI. To address these issues, we have introduced new enhancement indices derived from saturation-recovery snapshot-FLASH (SRSF) images. The stability of ...

Abstract Objective: To examine and compare the maxillofacial characteristics affecting chin deviation three-dimensionally in facial asymmetry patients with mandibular retrusion and mandibular prognathism. Materials and Methods: Maxillofacial computed tomography (CT) scan data were obtained from 48 orthognathic surgery patients (24 cases of mandibular retrusion and 24 cases of mandibular prognathism) ...

The successful delivery of anti-cancer drugs relies on the simultaneous capability to actively target a specific location, a sufficient lifetime in the active form in the circulation, and traceability and quantification of drug distribution via in vivo medical imaging. Herein, a highly magnetic nanocarrier (HMNC) composed of an Fe(3)O(4) core and ...

OBJECTIVES: Atherosclerotic plaque features, such as fibrous cap erosion, ulceration and rupture and presence of haemorrhage in carotid plaque are two important characteristics associated with subsequent cerebrovascular events and juxtaluminal haemorrhage/thrombus (JLH/T) indicates these two high-risk characteristics. This study aims to investigate the association between JLH/T and subsequent events in ...

Abstract Purpose: To validate a newly developed semi-automatic multispectral magnetic resonance imaging (MRI) tool for quantitatively monitoring aneurysm sac contents in patients after endovascular aneurysm repair (EVAR). Methods: MRI studies from 24 EVAR patients were retrospectively analyzed. The precontrast T(1)-weighted and T(2)-weighted and the postcontrast T(1)-weighted images were displayed simultaneously. ...

Animal models of partial hepatic ischemia-reperfusion injury (IRI) have potential benefits for decision making and clinical management after liver transplantation or massive hepatic resection. We evaluated changes in apparent diffusion coefficient (ADC) in rabbits with partial hepatic IRI using 3.0 T magnetic resonance diffusion-weighted imaging (DWI). Rabbits underwent 60 minutes ...

In this study, a static magnetic field influence on development and viability in two different species, Drosophila melanogaster and Drosophila hydei, was investigated. Both species completed development (egg-adult), in and out of the static magnetic field induced by double horseshoe magnet. Treated vials with eggs were placed in the gap ...

The purpose of this study was to determine the ex vivo ability of dual-energy dual-source CT (DSCT) with additional tin filtration to differentiate among five groups of human renal stone types. Forty-three renal stones of 10 types were categorized into five primary groups on the basis of effective atomic numbers, ...

The purpose of our study was to evaluate the value of dual-source dual-energy CT with colored iodine overlay for detection of endoleaks after endovascular abdominal aortic aneurysm repair. We also calculated the potential dose reduction by using a dual-energy CT single-phase protocol. From November 2007 to November 2009, 74 patients ...

The aim of this study was to develop a signal-inducing bone cement for magnetic resonance imaging (MRI)-guided cementoplasty of the spine. This MRI cement would allow precise and controlled injection of cement into pathologic lesions of the bone. We mixed conventional polymethylmethacrylate bone cement (PMMA; 5 ml methylmethacrylate and 12 g polymethylmethacrylate) ...

: The aim of this study was to analyze the differences in deficits in fine motor control and pinch grip force between patients with minimal, moderate/mild, or severe carpal tunnel syndrome (CTS) and healthy age- and hand dominance-matched controls. : A case-control study was conducted. The subtests of the Purdue ...

The purpose of this study was to evaluate the image quality (IQ) of dual-source CT (DSCT) versus single-source CT (SSCT). A total of 100 patients underwent 64-section CT coronary angiography (50 DSCT, 50 SSCT). Three observers evaluated the IQ of each coronary segment using a four-point scale (1, excellent; 2, ...

The purpose of this study was to determine the finding most predictive for characterizing hypervascular hepatocellular carcinoma (HCC) measuring 1 cm or less at gadoxetic acid-enhanced MRI that includes diffusion-weighted images. In this retrospective study, between May 2008 and June 2009, 66 patients with 108 hypervascular HCCs 1 cm or ...

Treatment for newly diagnosed anaplastic oligodendroglial tumors is controversial. Radiotherapy (RT) alone and in combination with chemotherapy (CT) are the most well studied strategies. However, CT alone is often advocated, especially in cases with 1p19q codeletion. We retrospectively identified 1013 adults diagnosed from 1981-2007 treated initially with RT alone (n ...

Cold preservation injury influences islet graft function. Reliable tools for real-time assessment of pancreas viability before islet isolation are lacking. Phosphorus magnetic resonance spectroscopy ((31)P-MRS) was used immediately after organ harvest to study rat pancreases at 4°C to 6°C in five randomized preservation groups: Marshall's solution, static two-layer method (TLM), ...

The purpose of our study was to evaluate the effect of a low tube voltage-high tube current-time product technique for portal phase abdominal CT of thin adults. This study included 25 patients who had undergone portal phase abdominal CT at 120 kVp in the preceding 6 months. All were scanned ...

The purpose of this article is to describe the development of an automated tool for retrieving texts from CT dose report images. Optical character recognition was adopted to perform text recognitions of CT dose report images. The developed tool is able to automate the process of analyzing multiple CT examinations, ...

OBJECTIVE: To compare dose and image quality of 64-slice, first and second generation dual-energy CT (DECT) for CT pulmonary angiography (CTPA). METHODS: Totally 120 patients, 30 in each group, underwent CTPA on a first generation (group 1: single-energy, 120 kV/145 mAs; group 2: DE, 140/80 kV, 70/350 mAs) or second generation dual-source ...

Object Accurate real-time imaging of coinfused surrogate tracers can be used to determine the convective distribution of therapeutic agents. To assess the effect that a concentration of a Gd-based surrogate tracer has on the accuracy of determining the convective distribution, the authors infused different concentrations of Gd-diethylenetriamine pentaacetic acid (DTPA) ...

OBJECTIVES: Technetium-99m (Tc)-sestamibi is the current radionuclide of choice for parathyroid localization in primary hyperparathyroidism (PH). However, there are only sporadic reports about brown tumor visualization in whole-body Tc-sestamibi scans. This study aimed to systematically evaluate brown tumor uptake in whole-body Tc-sestamibi scans and in whole-body bone scans as well. ...

PURPOSE: The purpose of our study was to compare diffusion-weighted MR imaging (DWI) with conventional dynamic MRI in terms of the assessment of small intrahepatic metastases from hepatocellular carcinoma (HCC). MATERIALS AND METHODS: In 24 patients with multifocal, small (≤2 cm) intrahepatic metastatic foci of advanced HCC, a total of ...

Aim: To evaluate diffusion-weighted MR imaging (DWI), gadoxetic acid-enhanced MR imaging and the combination of both methods in the detection, classification, and characterization of focal liver lesions (FLL). Methods: A total of 119 FLL (28 HCCs, 39 metastases, 15 FNHs, 11 adenomas, 13 hemangiomas, 13 cysts) were retrospectively analyzed in ...

ABSTRACT: BACKGROUND: The preoperative detection of emphysema like changes (ELCs) is necessary for the successful treatment of pneumothorax. High resolution computed tomography (HRCT) has been used for the preoperative detection of ELCs. However, the traditional HRCT method uses only the axial view, which is perpendicular to the distribution of ELCs. ...

PURPOSE: To compare the incidence of contrast medium-induced acute kidney injury (AKI) after intravenous (IV) administration of iodixanol for computed tomographic (CT) angiography versus intraarterial (IA) injection of iodixanol or low osmolar contrast medium (LOCM) for digital subtraction angiography (DSA) within the same population suspected of peripheral arterial occlusive disease ...

Backgound Magnetic resonance imaging (MRI) with several sequences may provide a valuable additional modality for evaluating the grade of invasiveness lesions. Diffusion-weighted magnetic resonance imaging (DWI) represents the biological characteristics of tissues. Purpose To retrospectively evaluate the usefulness of DWI for evaluating the invasiveness of small lung adenocarcinomas. Material and ...

In a group of oncologic patients undergoing (18)F-FDG PET/CT, we compared 4 different protocols of hydration to investigate their impact on image quality and to choose the best practice. METHODS: One hundred twenty subjects undergoing (18)F-FDG PET/CT were randomized into 4 groups: group A, receiving free oral hydration; group B, ...

The choice of injected dose of (18)F-FDG and acquisition time is important in obtaining consistently high-quality PET images. The aim of this study was to determine the optimal acquisition protocols based on patient weight for 3-dimensional lutetium oxyorthosilicate PET/CT. METHODS: This study was a retrospective analysis of 76 patients ranging ...

The purpose of this study was to investigate how the choice of the scanned region affects organ doses in CT. ImPACT CT Patient Dosimetry Calculator (version 1.0) was used to compute absorbed doses to eight organs of interest in medical radiation dosimetry. For 13 dosimetry data sets, the authors calculated ...

The treatment capacity of an integrated constructed treatment system (CTS) was explored which was designed to reduce phosphorus (P) from secondary effluents. The integrated CTS was combined with vertical-flow constructed wetland, floating bed and sand filter. The vertical wetland was filled from the bottom to the top with gravels, steel ...

PURPOSE: To evaluate the effect of a small field of view (FOV) for step-and-shoot coronary computed tomography angiography (CCTA) on craniocaudal z-coverage per scan step, image quality, and radiation exposure. METHODS: 53 patients underwent prospectively ECG-gated CCTA on a 256-slice MDCT scanner using either a FOV>250mm (group 1, n=29) or ...

The aim of the study was to evaluate the uptake of [(18)F]-1-deoxy-1-fluoro-scyllo-inositol ([(18)F]-scyllo-inositol) in human breast cancer (BC) and glioma xenografts, as well as in inflammatory tissue, in immunocompromised mice. Studies of [(18)F]-2-fluoro-2-deoxy-d-glucose ([(18)F]-FDG) under the same conditions were also performed. Radiosynthesis of [(18)F]-scyllo-inositol was automated using a commercial synthesis ...

The standardized uptake value (SUV) is a quantitative measure of FDG tumor uptake frequently used as a tool to monitor therapeutic response. This study aims to (i) assess the reproducibility and uncertainty of SUV max and SUV mean, due to purely statistical, i.e., nonbiological, effects and (ii) to establish the ...

Electromagnetic fields have been proposed to enhance healing of cartilage defects by stimulation of chondrocyte proliferation, proteoglycan synthesis as well as decreasing pain and improving motion in osteoarthritic patients. However, the effects of a moderate-intensity static magnetic field on cartilage repair have not been investigated. This study tries to determine ...

Clear depiction of the common bile duct is important when evaluating neonatal cholestasis in order to differentiate biliary atresia from other diseases. During MR cholangiopancreatography, the T2-shortening effect of gadolinium can increase the contrast-to-noise ratio (CNR) of the bile duct and enhance its depiction. The purpose of this study was ...

We wanted to validate the additional merit of the thinner coronal reformation images from multidetector CT (MDCT) for making the diagnosis of hepatic cysts. For the 90 benign hepatic cysts confirmed on MRI, the transverse (5-mm thickness) and additional coronal (2-mm thickness) reformation images from MDCT were compared with each ...

We wanted to evaluate the image quality, diagnostic accuracy and radiation exposure of 64-slice dual-source CT (DSCT) coronary angiography according to the heart rate in symptomatic patients during daily clinical practice. We performed a retrospective search for the DSCT coronary angiography reports of 729 consecutive symptomatic patients. For the 131 ...

ABSTRACT: The methods of the published manuscript [Jasmin et al, Optimized labeling of bone marrow mesenchymal cells with superparamagnetic iron oxide nanoparticles and in vivo visualization by magnetic resonance imaging. Journal of Nanobiotechnology 2011, 9:4] state that an incorrect concentration of Feridex was used (25 ug/ml). Instead, the methods should ...

Aim  Conventional white-light endoscopy is currently the gold standard for the detection and treatment of colorectal polyps. However, up to a fifth of polyps may be missed on initial examination, especially flat and small mucosal lesions. This study reviews the literature reporting on the use of new advances in endoscopic ...

The application of computer-aided detection (CAD) is expected to improve reader sensitivity and to reduce inter-observer variance in computed tomographic (CT) colonography. However, current CAD systems display a large number of false-positive (FP) detections. The reviewing of a large number of FP CAD detections increases interpretation time, and it may ...

To evaluate the utility of gadoxetic acid-enhanced hepatocyte-phase magnetic resonance imaging (MRI) in characterization of T1-weighted hyperintense nodules within cirrhotic liver. This retrospective study was approved by our Institutional Review Board. Thirty-four nodules hyperintense in unenhanced T1-weighted MRI with histopathological confirmation from a collection of 19 patients were included. Tumor ...

The aim of this study was to evaluate the effect of liquid crystal display (LCD) monitor type and observer experience on the diagnostic performance in soft-copy interpretations of maxillary sinus inflammatory lesions on panoramic radiographs. Ninety maxillary sinuses on panoramic images were grouped into negative and positive groups according to ...

Topical nasal sprays are commonly prescribed for sinonasal disease. Nasal drops applied in a head-down position are described alternatively to sprays. Multiple research methods have investigated the deposition pattern of intranasal medications, each with limitations. This pilot study analyzed the use of a conebeam computed tomography (CBCT) scanner to study ...

To evaluate the potential difference in post-contrast T(1) relaxation time of the meniscus (T(1Gd) ) between osteoarthritic patients (OA) and healthy subjects (HS), and to verify if charge density has any influence on meniscal T(1Gd) . We performed a retrospective analysis of meniscal T(1) relaxation time on data previously acquired ...

The purpose of this study was to determine the utility of three-dimensional (3D) automatic exposure control (AEC) for low-dose CT examination in a chest phantom study. A chest CT phantom including simulated focal ground-glass opacities (GGOs) and nodules was scanned with a 64-detector row CT with and without AEC. Performance ...