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Vathana Chhut Serey CS 1Department of Pathology at Sihanouk Hospital Center of HOPE, Cambodia 2Department of Pathology in Aurich, - - 2014
Cambodia is one of underserved countries in Southeast Asia and is still suffering from its terrible history in the last 30 years when no pathologist survived from the genocide of Khmer Rouge regime. Today only 8 pathologists, mostly under qualified, are on service for more than 14 million inhabitants. There ...
Tempaku Akira A Department of Neurosurgery, Hokuto Hospital, Hokkaido 080-0833, - - 2014
Ameloblastic carcinoma, secondary type, is an extremely rare odontogenic malignant tumor. The present study reports the case of a 58-year-old male with ameloblastic carcinoma that extended into the intracranial space close to the internal carotid artery. Surgical excision was performed, as headaches were being caused via compression by the mass. ...
Hong San-Fu SF Department of Otorhinolaryngology, Head and Neck Surgery, Changhua Christian Hospital, 135 Nanxiao St, Changhua City, Changhua County, 500, Taiwan, - - 2014
The aim of this study was to assess the clinical usefulness of three-dimensional (3D) color Doppler ultrasonography with a novel predictive model in the detection of cervical metastasis of untreated head and neck squamous cell carcinoma patients. We assessed cervical lymph node metastasis in 52 head and neck squamous cell ...
Sirin Selma S From the *Department of Diagnostic and Interventional Radiology and Neuroradiology, and †Clinic for Pediatrics II, University Hospital Essen, University of Duisburg-Essen, Essen, - - 2014
Magnetic resonance colonography (MRC) is a well-accepted, noninvasive imaging modality for the depiction of inflammatory bowel disease. Diffusion-weighted imaging (DWI) is very helpful to display inflammatory lesions. The aim of this retrospective study was to assess whether intravenous contrast is needed to depict inflammatory lesions in bowel magnetic resonance imaging ...
Mileto Achille A From the Department of Radiology (A.M., R.C.N., D.M., L.M.H.) and Carl E. Ravin Advanced Imaging Laboratories (K.R.C.), Duke University Medical Center, Box 3808, Erwin Rd, 2301 Durham, NC - - 2014
Purpose To determine whether contrast material-enhanced dual-energy multidetector computed tomography (CT) with material decomposition analysis allows differentiation of adrenal adenomas from nonadenomatous lesions and to compare findings with those of nonenhanced multidetector CT. Materials and Methods This retrospective HIPAA-compliant study was approved by the institutional review board of Duke University, ...
- - 2014
The rules on pet travel are due to change in December 2014.
Ababneh Bashar B Co-primary authors (contributed equally) Division of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Texas, - - 2014
Calcification in atherosclerotic plaques has been viewed as a marker of plaque stability, but whether calcification accumulates in specific anatomic sites in the carotid artery is unknown. We determined the burden and distribution of calcified plaque in carotid endarterectomy (CEA) tissues. A total of 22 CEA tissues were imaged with ...
Porcel José M - - 2014
BackgroundThe role of FDG-PET imaging for diagnosing malignant pleural effusions is not well defined. The aim of this study was to summarize the evidence for its use in ruling in or out the malignant origin of a pleural effusion and/or thickening. MethodsMeta-analysis of diagnostic accuracy studies published in the Cochrane ...
Lisanti Christopher J CJ 1 Department of Radiology, San Antonio Military Medical Center, 3851 Roger Brooke Dr, Fort Sam Houston, San Antonio, TX - - 2014
OBJECTIVE. The purpose of this study is to compare CT urography (CTU) with unenhanced CT in the evaluation of upper urinary tracts in adults younger than 50 years with asymptomatic microscopic hematuria. MATERIALS AND METHODS. In this study, 1516 CTU examinations were reviewed in adults younger than 50 years. Inclusion ...
Choi Jin-Young JY From the Department of Radiology, Research Institute of Radiological Science, Yonsei University Health System, Seoul, Korea (J.Y.C.); Department of Radiology and Institute of Radiation Medicine, Seoul National University Hospital, Seoul, Korea (J.M.L.); and Liver Imaging Group, Department of Radiology, University of California, San Diego Medical Center, 408 Dickinson St, San Diego, CA 92103-8226 - - 2014
Computed tomography (CT) and magnetic resonance (MR) imaging play critical roles in the diagnosis and staging of hepatocellular carcinoma (HCC). The first article of this two-part review discusses key concepts of HCC development, growth, and spread, emphasizing those features with imaging correlates and hence most relevant to radiologists; state-of-the-art CT ...
Filippo Massimo De MD Department of Surgical Sciences, Section of Diagnostic Imaging, University Hospital of Parma, Parma, Italy. - - 2014
We aimed to assess the correlation between pulmonary hemorrhage and pneumothorax in computed tomography (CT)-guided transthoracic fine needle aspiration (TTFNA), particularly its possible value as protection against the development of pneumotorax. We reviewed the CT images of 538 patients (364 males and 174 females, mean age 70 years, range 36-90 ...
Chen Yu Y Department of Diagnostic Radiology, Cancer Institute and Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, No. 17 Panjiayuannanli Chaoyang District, Beijing, 100021, - - 2014
To compare the diagnostic performance of contrast-enhanced ultrasound (CEUS) with MRI for complex cystic renal masses. The study received approval from our Ethics Committee, and all subjects provided informed consent. Seventy-one complex cystic renal masses were assessed using CEUS and MRI in 59 patients (44 men and 15 women; age ...
Liu Dan D From the Departments of Diagnostic Radiology (D.L., P.L.K.) and Surgery (A.C.Y.C., R.T.P.P.), Queen Mary Hospital, University of Hong Kong, 102 Pokfulam Rd, Hong Kong; and School of Nursing, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong - - 2014
Purpose To evaluate alternative schedules for surveillance computed tomography (CT) for patients who underwent hepatectomy for hepatocellular carcinoma (HCC) and to demonstrate an appropriate schedule on the basis of stratification for risk of recurrence. Materials and Methods CT and pathologic reports for consecutive patients with HCC who underwent hepatectomy at ...
Kojima Katsuhide K Department of Diagnostic Radiology 2, Kawasaki Hospital, Kawasaki Medical School, 2-1-80, Nakasange Kita-ku, Okayama, 700-8505, Japan, - - 2014
Pulmonary alveolar proteinosis (PAP) is a rare diffuse lung disease caused by abnormal intra-alveolar surfactant accumulation; it commonly appears as a "crazy-paving" pattern on high-resolution computed tomography. Here, we report a rare case of autoimmune PAP appearing as localized ground-glass opacity. An 82-year-old woman underwent chest computed tomography (CT) at ...
Ryu In Sun IS Department of Otolaryngology, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Republic of - - 2014
Accurate tumor staging including involvement of laryngeal cartilage is important to treatment planning. Clinicians rely on imaging findings and determine initial laryngectomy for T4-stage cancer with functionless larynx or extralaryngeal spread (ELS). We examined the accuracy and prognostic value of preoperative CT findings for tumor staging in patients with locally ...
Munich Stephan A SA Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois. Electronic address: - - 2014
Iodine-based contrast medium used in diagnostic and therapeutic cerebrovascular imaging may cause renal toxicity, especially in patients with underlying renal impairment. Contrast dilution may impede efforts of the neurointerventionalist to treat intracranial vascular pathology. A 36-year-old man with renal impairment presented with an unruptured A1 segment anterior cerebral artery aneurysm. ...
Grady A T AT From the Departments of Radiology (A.T.G., T.P.T., K.R.C., R.T.G., J.K.H.), Surgery (J.A.S.), and Radiation Oncology (J.K.H.), Duke Cancer Institute (J.A.S.), and Duke Clinical Research Institute (J.A.S.), Duke University Medical Center, Durham, North - - 2014
Variability in radiologists' reporting styles and recommendations for incidental thyroid nodules can lead to confusion among clinicians and may contribute to inconsistent patient care. Our aim was to describe reporting practices of radiologists for incidental thyroid nodules seen on CT and MR imaging and to determine factors that influence reporting ...
Zanotti-Fregonara Paolo - - 2014
The imaging of translocator 18kDa protein (TSPO) in living human brain with radioligands by positron emission tomography (PET) has become an important means for the study of neuroinflammatory conditions occurring in several neuropsychiatric disorders. The widely used prototypical PET radioligand, [(11)C](R)-PK 11195 ([(11)C](R)-1; [N-methyl-(11C)](R)-N-sec-butyl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide), gives low PET signal and is ...
Zegarra-Linares Ricardo - - 2014
Abstract We report the case of a 15-year-old girl who presented with a history of recurrent bitemporal headaches for the last 2 months. In the prior few days, she complained of neck pain, emesis, phonophobia and photophobia, but no fever. Additional symptoms included polydipsia, polyuria and weight gain in the ...
Polyak Andras A National "F.J.C." Research Institute for Radiobiology and Radiohygiene (NRIRR), Budapest, Hungary. Electronic address: - - 2014
A new biocompatible, biodegradable, self-assembled chitosan-based nanoparticulate product was successfully synthesized and radiolabeled with technetium-99m, and studied as a potential new SPECT or SPECT/CT imaging agent for diagnosis of folate receptor overexpressing tumors. In the present study we examined the conditions of a preclinical application of this labeled nanosystem in ...
Lukas Scott E SE McLean Imaging Center, McLean Hospital, NIC Mail Stop 319, 115 Mill St., Belmont, MA 02478; Behavioral Psychopharmacology Research Laboratory, McLean Hospital, NIC Mail Stop 319, 115 Mill St., Belmont, MA 02478; Harvard Medical School, McLean Hospital, NIC Mail Stop 319, 115 Mill St., Belmont, MA 02478. Electronic address: - - 2014
While the recent application of brain imaging to study CNS stimulants has offered new insights into the fundamental factors that contribute to their use and abuse, many gaps remain. Brain circuits that mediate pleasure, dependence, craving and relapse are anatomically, neurophysiologically and neurochemically distinct from one another, which has guided ...
Yang Jun J MIMR-PHI Medical Research Institute, Clayton, Victoria 3168, - - 2014
The mineralocorticoid receptor (MR) plays a central role in salt and water homeostasis via the kidney; however, inappropriate activation of the MR in the heart can lead to heart failure. A selective MR modulator that antagonizes MR signaling in the heart but not the kidney would provide the cardiovascular protection ...
Ambrosini Valentina V Nuclear Medicine, S.Orsola-Malpighi University Hospital, via Massarenti 9, Bologna 40138, Italy. Electronic address: - - 2014
Somatostatin receptors (SSTR) are expressed on neuroendocrine cells widely dispersed in the human body. Neuroendocrine tumors (NET) are characterized by increased SSTR expression and may virtually arise anywhere in the human body. The diagnostic flowchart of NET patients has been completely revolutionized in the past few years as a consequence ...
Kamaleshwaran Koramadai Karuppusamy KK Department of Nuclear Medicine, PET/CT and Radionuclide Therapy, Comprehensive Cancer Care Centre, Kovai Medical Centre and Hospital Limited, Coimbatore, Tamil Nadu, - - 2014
Pulmonary sclerosing hemangioma (PSH), or the alternative name of "sclerosing pneumocytoma," is a rare benign neoplasm. PSH is often asymptomatic and presents as a solitary or multiple pulmonary nodules on radiologic imaging studies. Few articles have been reported to describe the fluorodeoxyglucose positron emission tomography (FDG PET) findings about PSH. ...
D'souza Maria M MM Department of Positron Emission Tomography Imaging, Institute of Nuclear Medicine and Allied Sciences, Delhi, - - 2014
A 37-year-old male who underwent a central hepatectomy of the liver for hepatocellular carcinoma (HCC) was referred for an (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) study to rule out tumor recurrence or metastases. The scan showed a recurrent hepatic mass at the operative site, along with low-grade uptake in ...
Gupta Madan Mohan MM Department of Radiodiagnosis, Meghrajji Pethrajji. Shah Govt. Medical College and Guru Govind Singh Government Hospital, Jamnagar, Gujarat, - - 2014
Multifocal osteosarcoma is diagnosed when there are two or more lesions in the skeleton without presence of pulmonary metastases. It is further classified as synchronous type when the patient is demonstrated to have more than one lesion simultaneously at presentation and is known as Synchronous Multifocal Osteogenicsarcoma (MOGS). We report ...
Karunanithi Sellam S Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, - - 2014
The central nervous system metastasis from nasopharyngeal carcinoma (NPC) is an extremely rare occurrence, although direct intracranial invasion is not infrequent in patients with NPC. Herein we report a case of a 62-year-old male with NPC, in whom the asymptomatic cauda equina metastasis was detected on staging (18)F-Fluordeoxyglucose positron emission ...
Malkova Natalia V NV Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125; and - - 2014
Maternal infection during pregnancy increases the risk for schizophrenia in offspring. In rodent models, maternal immune activation (MIA) yields offspring with schizophrenia-like behaviors. None of these behaviors are, however, specific to schizophrenia. The presence of hallucinations is a key diagnostic symptom of schizophrenia. In mice, this symptom can be defined ...
Tang Dewei D Vanderbilt University Institute of Imaging Science (VUIIS), Vanderbilt University Medical Center, 1161 21st Ave. S., AA 1105 MCN, Nashville, TN, 37232-2310, - - 2014
Translocator protein (TSPO) concentrations are elevated in glioma, suggesting a role for TSPO positron emission tomography (PET) imaging in this setting. In preclinical PET studies, we evaluated a novel, high-affinity TSPO PET ligand, [(18)F]VUIIS1008, in healthy mice and glioma-bearing rats. Dynamic PET data were acquired simultaneously with [(18)F]VUIIS1008 injection, with ...
Dawson Dana K DK Cardiovascular Medicine Research Unit, University of Aberdeen, Aberdeen, United Kingdom. Electronic address: - - 2014
Insufficient precision remains in accurately identifying left ventricular noncompaction (LVNC) from the healthy normal morphologic spectrum. We aim to provide a better distinction between normal left ventricular trabeculations and LVNC. We used a previously well-defined cohort of 120 healthy volunteers for normal reference values of the trabecular/compacted ratio derived from ...
Lai Ji Ching - - 2014
A new SELEX protocol for the development of DNA aptamers has been demonstrated, referred to as Magnetic-Assisted Rapid Aptamer Selection (MARAS). This method uses magnetic beads and an externally-applied rotating magnetic field to provide the competitive mechanism for the selection aptamers with different affinities to the molecular target. The MARAS ...
Park Jihyun J Department of Nuclear Medicine, Korea Cancer Center Hospital, 75, Nowon-ro, Nowon-gu, Seoul, 139-706 Republic of - - 2014
Increased (18)F-fluorodeoxyglucose (FDG) uptake of brown fat on (18)F-FDG positron emission tomography (PET) originating from physiological activation is a common incidental finding and is usually located in the neck, shoulder, and supraclavicular areas. We present a case of an incidental pheochromocytoma showing diffusely increased (18)F-FDG uptake in bilateral perirenal fat ...
Aparici Carina Mari CM Department Radiology, Nuclear Medicine Section, UCSF, San Francisco, CA, - - 2014
We present a case of a 60-year-old white male with a history of papillary renal cell carcinoma (PRCC) status postpartial nepherectomy. He was followed-up annually with abdominal computed tomography (CT) scans to monitor for tumor recurrence. A solitary metastatic bony lesion was detected by CT 4 years after partial nephrectomy ...
Lu Hong H Department of Radiology, Affiliated Haikou Hospital, Xiangya School of Medicine, Central South University, Haikou, Hainan Province, - - 2014
After traumatic brain injury, vasogenic and cytotoxic edema appear sequentially on the involved side. Neuroimaging investigations of edema on the injured side have employed apparent diffusion coefficient measurements in diffusion tensor imaging. We investigated the changes occurring on the injured and uninjured sides using diffusion tensor imaging/apparent diffusion coefficient and ...
Kalavagunta Chaitanya C Center of Magnetic Resonance Research, University of Minnesota, Minneapolis, Minnesota, - - 2014
To present a novel registration approach called LATIS (Local Affine Transformation guided by Internal Structures) for coregistering post prostatectomy pseudo-whole mount (PWM) pathological sections with in vivo MRI (magnetic resonance imaging) images. Thirty-five patients with biopsy-proven prostate cancer were imaged at 3T with an endorectal coil. Excised prostate specimens underwent ...
Yoon Hai-Jeon HJ Department of Nuclear Medicine, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 110-744, - - 2014
Imaging biomarkers from functional imaging modalities were assessed as potential surrogate markers of disease status. Specifically, in this prospective study, we investigated the relationships between functional imaging parameters and histological prognostic factors and breast cancer subtypes. In total, 43 patients with large or locally advanced invasive ductal carcinoma (IDC) were ...
Pugash Denise D Department of Radiology, British Columbia Women's Hospital and University of British Columbia, Vancouver, - - 2014
Thanatophoric dysplasia, hypochondroplasia and achondroplasia are all caused by FGFR3 (fibroblast growth factor receptor 3) mutations. Neuropathological findings of temporal lobe dysplasia are found in thanatophoric dysplasia, and recently, temporal and occipital lobe abnormalities have been described in brain imaging studies of children with hypochondroplasia. We describe twins discordant for ...
Peter Luisa L From the *Department of General and Visceral Surgery, Zentralklinik Bad Berka, ENETS Center of Excellence; †Laboratory of Pathology and Cytology; and ‡Department of Molecular Radiotherapy/Center for Molecular Imaging (PET/CT), Zentralklinik Bad Berka, ENETS Center of Excellence, Bad Berka, - - 2014
Ga somatostatin receptor PET/CT, currently the most sensitive imaging modality for well-differentiated neuroendocrine tumors, is based on the molecular imaging of somatostatin receptors (SSTRs) that are expressed in different tumor entities such as neuroendocrine neoplasms, lymphomas, meningiomas, or renal cell cancer (RCC). Most neuroendocrine neoplasms show a high expression of ...
Jadhav Swati S Department of Endocrinology, KEM hospital, Mumbai, - - 2014
Localisation of phosphatonin producing mesenchymal tumours in patients with primary tumour-induced osteomalacia (pTIO) is challenging. Functional imaging plays an important role in the localisation of these tumours. We studied the relative performance of different functional imaging modalities ((18) F-FDG PET CT, (99) Tc HYNIC TOC SPECT CT and (68) Ga ...
Pirayesh Elahe E Department of Nuclear Medicine, Shohada e Tajrish Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran; - - 2014
The diagnostic usefulness of somatostatin receptor scintigraphy in the localization of tumors has been evaluated in several studies. Here, we present the case of a patient with a subserosal myoma diagnosed by (99m)Tc-labeled octreotide acetate scintigraphy. Oval and ring-shaped areas of hyperactivity in the pelvis were confirmed on MR imaging ...
Stoessl A Jon - - 2014
Positron emission tomography (PET) is a powerful technique to quantitatively assess brain function in vivo. In Parkinson's disease (PD), PET can assist in the identification of dopamine deficiency, the characterization of dopamine and other neurotransmitter receptors and transporters, serve as a biomarker and provide insights into motor and non-motor complications ...
Kuhn Felix P FP Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, Zurich 8091, Switzerland. - - 2014
Quantitative measures of 11C-raclopride receptor binding can be used as a correlate of postsynaptic D2 receptor density in the striatum, allowing 11C-raclopride positron emission tomography (PET) to be used for the differentiation of Parkinson's disease from atypical parkinsonian syndromes. Comparison with reference values is recommended to establish a reliable diagnosis. ...
Munro Kirsty I KI MRC Centre for Reproductive Health, University of Edinburgh, Edinburgh, United - - 2014
There are no long-term medical treatments for uterine fibroids, and non-invasive biomarkers are needed to evaluate novel therapeutic interventions. The aim of this study was to determine whether serial dynamic contrast-enhanced MRI (DCE-MRI) and magnetization transfer MRI (MT-MRI) are able to detect changes that accompany volume reduction in patients administered ...
de Herder Wouter W WW Section of Endocrinology, Department of Internal Medicine, Erasmus MC, 's Gravendijkwal 230, 3015 CE Rotterdam, The - - 2014
For patients with neuroendocrine tumours (NETs) of the gastrointestinal tract and pancreas (GEP) (GEP-NETs), excellent care should ideally be provided by a multidisciplinary team of skilled health care professionals. In these patients, a combination of nuclear medicine imaging and conventional radiological imaging techniques is usually mandatory for primary tumour visualisation, ...
Choi Hongyoon H Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea; Department of Molecular Medicine and Biopharmaceutical Science, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of - - 2014
Metabotropic glutamate receptor 5 (mGluR5) that regulates glutamatergic neurotransmission contributes to pathophysiology of epilepsy. In this study, we monitored the changes of mGluR5 in vivo using [11C]ABP688 PET during the epileptogenesis in a pilocarpine-induced epilepsy rat model. In vivo mGluR5 images were acquired using [11C]ABP688 microPET/CT in pilocarpine-induced chronic epilepsy ...
Sengoku Renpei R Department of Neurology, The Jikei University School of Medicine, - - 2014
We herein report that the clinical, laboratory, and radiographic features and positron emission tomography (PET) imaging may provide valuable clues to the pathogenesis of cerebral amyloid angiopathy (CAA)-associated encephalopathy, which currently remains unclear. We herein describe two cases of encephalopathy with CAA, with an emphasis on PET imaging with (11)C-Pittsburgh ...
Padma Subramanyam S Department of Nuclear Medicine and PETCT, Amrita Institute of Medical Sciences and Research Centre, Cochin, Kerala, - - 2014
With technological advancements and wider availability of multimodality imaging, incidental lesions are frequently identified in patients undergoing various imaging studies. We report here a case of multiloculated disseminated perineural or Tarlov cysts (TCs). The primary aim of our study was to (1) provide a comprehensive review of the clinical, imaging ...
Chakraborty Dhritiman D Department of Nuclear Medicine and PET, Postgraduate Institute of Medical Education and Research, Chandigarh, - - 2014
Bladder carcinoma is the most frequent tumor of the urinary tract and accounts 7% of all malignancies in men and 2% of all malignancies in women. This retrospective study was carried out to assess the diagnostic utility of F18-fludeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in the imaging evaluation of ...
Mytsyk Yulian Y Department of Radiology, Lviv National Medical University, Lviv, - - 2014
Diffusion-weighted imaging (DWI) is an MRI modality using strong bipolar gradients to create a sensitivity of the signal to the thermally-induced Brownian motions of water molecules and in vivo measurement of molecular diffusion. The apparent diffusion coefficient (ADC) is a quantitative parameter calculated from DWI images which is used as ...
Song Hong H University of Maryland School of Medicine, United - - 2013
'Classic' cardiotonic steroids (CTS) such as digoxin and ouabain selectively inhibit Na(+),K(+)-ATPase (the Na(+) pump) and, via Na/Ca exchange (NCX), exert cardiotonic and vasotonic effects. CTS action is more complex than previously thought: prolonged subcutaneous administration of ouabain, but not digoxin, induces hypertension, and digoxin antagonizes ouabain's hypertensinogenic effect. We ...
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