PURPOSE: To test the potential of magnetic resonance imaging (MRI) in early detection of left ventricular (LV) dysfunction in patients with pulmonary regurgitation and normal LV ejection fraction after repair of tetralogy of Fallot. MATERIALS AND METHODS: Patients (n = 18) with repaired tetralogy of Fallot and pulmonary regurgitation were ...

ABSTRACT: BACKGROUND: Conventional magnetic resonance imaging (MRI) has improved the diagnosis and monitoring of multiple sclerosis (MS). In clinical trials, MRI has been found to detect treatment effects with greater sensitivity than clinical measures; however, clinical and MRI outcomes tend to correlate poorly. METHODS: In this observational study, patients (n=550; ...

PURPOSE: We evaluated the relationships between the cerebral metabolic rate of glucose (CMRglu) measured by dynamic (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) and the clinical and neuropsychological assessment before and after the surgical procedure in idiopathic normal pressure hydrocephalus (INPH) patients. METHODS: Eleven selected INPH patients underwent clinical assessment ...

OBJECTIVE: To characterize clinical and radiologic features of patients with central pontine myelinolysis (CPM) and identify variables that predict outcome.PATIENTS AND METHODS: We retrospectively studied patients diagnosed as having CPM identified by a search of Mayo Clinic medical records from January 1, 1999, through December 31, 2010. Diagnosis was made ...

BACKGROUND AND PURPOSE:Patients with MR imaging-negative epilepsy could have subtle FCD. Our aim was to determine if structural changes could be identified by using DTI in children with intractable epilepsy, from MR imaging-visible FCD and MR imaging-negative localization-related epilepsy, that were concordant with the epileptogenic zone as defined by using ...

BACKGROUND AND PURPOSE:EAF consists of exceedingly rare lesions and presently lacks specific imaging reports. The purpose of this study was to determine the CT and MR imaging features of nasal cavity EAF.MATERIALS AND METHODS:We retrospectively reviewed 6 patients with histology-proven EAF in the nasal cavity. All 6 patients underwent CT ...

A non-viral gene delivery nanovehicle based on Alkyl-PEI2k capped MnO nanoclusters was synthesized via a simple, facile method and used for efficient siRNA delivery and magnetic resonance imaging.

OBJECTIVES: To evaluate magnetic resonance imaging (MRI) findings in patients with primary biliary cirrhosis (PBC) and to determine the value of diffusion-weighted imaging (DWI) in the assessment of liver fibrosis. MATERIALS AND METHODS: The following MRI findings were reviewed in 44 patients: periportal T2-weighted hyperintensity, periportal halo sign (T1- and ...

PURPOSE: To evaluate the intermediate- and long-term imaging manifestations of radiotherapy on normal-appearing brain tissue in patients with treated gliomas using 7T susceptibility-weighted imaging (SWI). METHODS AND MATERIALS: SWI was performed on 25 patients with stable gliomas on a 7 Tesla magnet. Microbleeds were identified as discrete foci of susceptibility ...

We study the extent to which procalcitonin (Pro-CT) and/or C-reactive protein (CRP) may be helpful in the early triage of febrile patients admitted to a general internal medicine ward. This is a prospective, observational study on 62 admitted patients in whom a temperature >38°C had been observed the day before ...

Inflammation and angiogenesis are hypothesized to be important factors contributing to plaque vulnerability, whereas calcification is suggested to confer stability. To investigate this in vivo, we combined CT angiography and PET and compared the findings with immunohistochemistry for patients undergoing carotid endarterectomy. METHODS: Twenty-one consecutive patients (18 men, 3 women; ...

Testicular lymphoma represents the commonest testicular malignancy in men older than 50 years. MR imaging of the scrotum is an efficient supplemental diagnostic tool in the evaluation of scrotal diseases. We report two cases of primary diffuse large B-cell testicular lymphoma, presented in men over the age of 50 years. MR imaging ...

PURPOSE: The purpose of this study was to describe the MR imaging findings of cervical lymphadenopathy in patients with Kikuchi disease (histiocytic necrotizing lymphadenitis). MATERIALS AND METHODS: Nine patients with Kikuchi disease underwent MR imaging with a 1.5T unit including diffusion-weighted (DW) imaging and five of nine underwent gadolinium-enhanced MR ...

OBJECTIVES: To highlight a case series of 3 cases of focal cortical dysplasia that were unrecognized for many years though the patients were seen by various neurologists and received the appropriate neuroimaging studies, and to retrospectively characterize the clinical elements, neuroimaging, electroencephalography, and pathologic findings in these cases. DESIGN: Retrospective ...

PURPOSE: To determine if tissue magnetic susceptibility is a more direct marker of tissue iron content than other MR markers of iron. This study presents the first quantitative, in vivo measurements of the susceptibility of the substantia nigra in patients with Parkinson's disease. MATERIALS AND METHODS: Nine patients and 11 ...

White matter (WM) tract damage was assessed in patients with the behavioral variant frontotemporal dementia (bvFTD) and the 3 primary progressive aphasia (PPA) variants and compared with the corresponding brain atrophy patterns. Thirteen bvFTD and 20 PPA patients were studied. Tract-based spatial statistics and voxel-based morphometry were used. Patients with ...

OBJECTIVE: To assess the role of multidetector CT angiography (MDCTA) in the diagnosis of acute mesenteric ischemia (AMI) and to compare the diagnostic utility of axial images with reconstructed images. MATERIALS AND METHODS: In this Institute Review Board approved prospective study, MDCTA was performed on 31 patients who presented with ...

BACKGROUND: The purpose of this study was to analyze the detectability of colorectal neoplasia with fluorine-18-2-fluoro-2-deoxy-D: -glucose positron emission tomography/computed tomography (FDG-PET/CT). METHODS: Data for a total of 492 patients who had undergone both PET/CT and colonoscopy were analyzed. After the findings of PET/CT and colonoscopy were determined independently, the ...

OBJECTIVE:: To assess patient and medication factors that contribute to metronidazole toxicity. DATA SOURCES:: We searched PUBMED from 1965 through April 7, 2011, and performed a hand search of bibliographies. STUDY SELECTION:: Case reports or case series reporting metronidazole-induced central nervous toxicity. DATA EXTRACTION:: Two authors independently abstracted demographics, metronidazole ...

PURPOSE: Quantitative assessment of 3D clinical indices may be crucial for elbow surgery planning. 3D parametric modeling from bi-planar radiographs was successfully proposed for spine and lower limb clinical investigation as an alternative for CT-scan. The aim of this study was to adapt this method to the upper limb with ...

BACKGROUND: The localization of enlarged parathyroid glands might, depending on size, histology, and concomitant goiter, be difficult in some patients. In the presented study, contrast-enhanced ultrasonography (CEUS) was applied as a new diagnostic tool to detect the site of parathyroid lesions. METHODS: Thirty patients underwent operation for primary hyperparathyroidism (pHPT) ...

BACKGROUND AND PURPOSE: Several retrospective studies suggested that contrast extravasation on CT angiography predicts hematoma expansion, poor outcome, and mortality in primary intracerebral hemorrhage. We aimed to determine the predictive value of contrast extravasation on multidetector CT angiography for clinical outcome in a prospective study. METHODS: In 160 consecutive patients ...

ABSTRACT: BACKGROUND: The indications, complexity and capabilities of cardiovascular magnetic resonance (CMR) have rapidly expanded. Whether actual service provision and training have developed in parallel is unknown. METHODS: We undertook a systematic telephone and postal survey of all public hospitals on behalf of the British Society of Cardiovascular Magnetic Resonance ...

OBJECTIVE: To evaluate the role of (68)Ga-labelled [1, 4, 7, 10-tetraazacyclododecane-1, 4, 7, 10-tetraacetic acid]-1-NaI(3)-Octreotide ((68)Ga-DOTA-NOC) whole body positron emission tomography-computed tomography (PET-CT) as a functional imaging approach for phaeochromocytoma and paraganglioma. METHODS: Thirty-five unrelated patients (Median age-34.4 years; range: 15-71) were evaluated in this prospective study. PET-CT was performed after ...

Abnormal high cerebral iron deposition may be implicated in chronic neurologic disorders, including multiple sclerosis (MS). R2* relaxometry has been recently validated in a postmortem study to indicate brain iron accumulation in a quantitative manner. We used this technique to assess brain iron levels in different stages of MS and ...

Current research suggests that effort indices designed for the detection of malingered neurocognitive functioning do not have adequate sensitivity or specificity for use in cases where malingered mental retardation (MR) is the issue. Therefore, development and validation of reliable, objective measures for the detection of malingered MR have become imperative ...

ABSTRACT: BACKGROUND: The application of advanced 3T MRI imaging techniques to study recovery after subarachnoid hemorrhage (SAH) is complicated by the presence of image artifacts produced by implanted aneurysm clips. To characterize the effect of these artifacts on image quality, we sought to: 1) quantify extent of image artifact in ...

Purpose:To measure diagnostic performance in the detection of hepatocellular carcinoma (HCC) by using the most recent technology and multiphase gadolinium-enhanced magnetic resonance (MR) imaging and to compare with earlier results at the same institution.Materials and Methods:This retrospective study was institutional review board approved and HIPAA compliant. Informed consent was obtained. ...

Purpose:To evaluate the diagnostic performance and effect on therapeutic management of 64-section computed tomographic (CT) angiography in the assessment of steno-occlusive disease in patients with peripheral arterial disease (PAD), with conventional digital subtraction angiography (DSA) as the reference standard.Materials and Methods:The study protocol was approved by the institutional review board, ...

BackgroundA systematic comparison of magnetic resonance imaging (MRI) options for glioma diagnosis is lacking.PurposeTo investigate multiple MR-derived image features with respect to diagnostic accuracy in tumor grading and survival prediction in glioma patients.Material and MethodsT1 pre- and post-contrast, T2 and dynamic susceptibility contrast scans of 74 glioma patients with histologically ...

: Facial allotransplantation requires a detailed arterial and venous assessment for surgical planning. Target vessels are often depleted by multiple reconstructive attempts or the severe facial injury itself. The purpose of this study was to retrospectively compare the diagnostic performance of computed tomography and magnetic resonance angiography in the preoperative ...

OBJECTIVE:: A systematic review to determine whether the diffusion-weighted (DW) magnetic resonance imaging scan can reliably detect residual or recurrent cholesteatoma after mastoid surgery. DESIGN:: A systematic review. DATA SOURCES:: Databases including EMBASE, MEDLINE, CINAHL, Web of Science, and Cochrane Review were searched for studies published without language restriction from ...

OBJECTIVE: The purpose of this study was to evaluate the technical feasibility of CT colonography of patients who have undergone sigmoid colostomy after abdominoperineal resection. MATERIALS AND METHODS: Seven men and 11 women (mean age, 57.2 ± 14.5 [SD] years) who had undergone abdominoperineal resection with sigmoid colostomy for rectal ...

BACKGROUND: The aim of this study was to evaluate the peritoneal computed tomography (CT) attenuation values and relate them to the severity of peritonitis in patients with gastrointestinal tract (GI) perforations. METHODS: A total of 56 consecutive patients with GI perforations who underwent CT scan and emergency laparotomy in our ...

INTRODUCTION: The aim of this study was to evaluate the efficacy of F-18-fluorodeoxyglucose positron emission tomography (FDG-PET) scanning in the staging of oesophageal adenocarcinoma. METHODS: One hundred four patients with biopsy-proven adenocarcinoma underwent (18)F-FDG-PET scan. FDG avid lesions were further investigated to their diagnostic conclusion. RESULTS: Nineteen patients (18.26%) were ...

OBJECTIVE: The aim of this study was to predict recurrence of hepatocellular carcinoma (HCC) from baseline dynamic CT images. MATERIALS AND METHODS: This retrospective study included 191 consecutive patients who underwent surgical resection or radiofrequency ablation (RFA) between January 2005 and September 2009 for the treatment of HCC. Enhancement on ...

: Evaluating the status of disease progression is critical for planning a therapeutic strategy for esophageal cancer. In this regard, F-18 fluorodeoxyglucose-labeled positron emission tomography (PET) is one of the most useful diagnostic modalities. However, there is room to improve its diagnostic performance, such as distinguishing lymph nodal metastases from ...

OBJECTIVE:: Three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) magnetic resonance imaging (MRI) has recently been applied to the inner ear, but the relationship between 3D-FLAIR findings and audiovestibular function has been unclear in patients with sudden sensorineural hearing loss (SSNHL). We therefore used 3D-FLAIR MRI to investigate vestibular lesions in patients with ...

OBJECTIVE: Magnetic resonance imaging (MRI) is commonly used in autoimmune inflammatory arthritis to define disease activity and damage, but its role in gout remains unclear. The aim of our study was to identify and describe the MRI features of gout. METHODS: Over a 10-year period we identified patients with gout ...

OBJECTIVE: The purpose of this article is to determine the negative appendectomy rates of patients who did and did not undergo preoperative CT and to determine, more specifically, whether men benefit from preoperative CT. MATERIALS AND METHODS: We identified 512 patients who had a nonincidental appendectomy between July 1, 2002, ...

OBJECTIVE: The objective of our study was to evaluate whether there is injury to the transverse ligament of the atlas in patients with acute whiplash. MATERIALS AND METHODS: Ninety patients with an acute (< 48 hours) symptomatic whiplash-associated injury and 90 healthy age- and sex-matched asymptomatic control subjects (mean age ...

: The purpose of this study is to evaluate the performance of gallium-67 scan (GS) and F-18 fluorodeoxyglucose (FDG) PET scan in lymphoma staging and recurrence detection by comparing the 2 imaging studies in the same patient. : A total of 42 patients from the period between July 2002 and ...

OBJECTIVE: The objective of our study was to retrospectively determine whether segmental enhancement inversion or other CT patterns seen at enhanced biphasic MDCT are predictive for the diagnosis of renal oncocytoma. MATERIALS AND METHODS: Twenty-nine patients with 32 oncocytomas diagnosed by either biopsy or resection who had undergone enhanced biphasic ...

: Because of paucity of data available regarding the utility of PET/CT in the diagnosis and staging of patients with olfactory neuroblastoma (ONB), we retrospectively analyzed the efficacy of PET/CT in 9 patients with ONB. : Whole-body F-18 FDG PET/CT was performed in 7 patients with newly diagnosed ONB, as ...

Objectives- Diagnosis of white matter damage by cranial ultrasound imaging is still subject to interobserver variability and has limited sensitivity for predicting abnormal neurodevelopment later in life. In this study, we evaluated the ability of a semiautomated method based on ultrasound texture analysis to identify patterns that correlate with the ...

Purpose: The choice of CT protocol can greatly impact patient dose and image quality. Since acquiring multiple scans at different techniques on a given patient is undesirable, the ability to predict image quality changes starting from a high quality exam can be quite useful. While existing methods allow one to ...

Background: We evaluated how comprehensive assessment of coronary artery lesions and their hemodynamic relevance by means of hybrid positron emission tomography (PET) and computed tomography (CT) imaging would affect decision-making in coronary artery bypass surgery (CABG), compared with using invasive coronary angiography (ICA) alone.Methods: After undergoing ICA, 27 patients (21 ...

This study sought to characterize the shape of regurgitant orifice area (ROA) and mitral apparatus in various forms of mitral regurgitation (MR) by cardiac magnetic resonance (CMR). ROA is an accepted parameter of MR severity. However, there are little data on the shape of the ROA in various forms of ...

Aim: The aim of this study was to evaluate the accuracy and clinical impact of single-reader breast MR (BMR) used as a clinical 'problem solving' tool. Methods: Observational, retrospective, ethics approved data collection for all BMR were from May 2006 to February 2009 (n = 143). Cases were stratified into groups according ...

Minor head injury (MHI) is a common injury seen in Emergency Departments (ED). Computed tomography (CT) scan of the brain is a good method of investigation to diagnose intracranial lesions, but there is a disagreement about indications in MHI patients. We surveyed the post-traumatic symptoms, signs or past historical matters ...