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Deviers Alexandra A Département de Radiothérapie, Institut Claudius Regaud, Toulouse, France; UMR (Unité Mixte de Recherche) 825, Institut National de la Santé et de la Recherche Médicale, Toulouse, France; INP (Institut National Polytechnique), ENVT (Ecole Nationale Vétérinaire de Toulouse), Unité d'Anatomie-Imagerie-Embryologie, Université de Toulouse, Toulouse, - - 2014
Because lactate accumulation is considered a surrogate for hypoxia and tumor radiation resistance, we studied the spatial distribution of the lactate-to-N-acetyl-aspartate ratio (LNR) before radiation therapy (RT) with 3D proton magnetic resonance spectroscopic imaging (3D-(1)H-MRSI) and assessed its impact on local tumor control in glioblastoma (GBM). Fourteen patients with newly ...
Lim Tze Yee TY The University of Texas at Houston Graduate School of Biomedical Sciences, 6767 Bertner Avenue, Houston, TX 77030, USA. Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, - - 2014
Brachytherapy, a radiotherapy technique for treating prostate cancer, involves the implantation of numerous radioactive seeds into the prostate. While the implanted seeds can be easily identified on a computed tomography image, distinguishing the prostate and surrounding soft tissues is not as straightforward. Magnetic resonance imaging (MRI) offers superior anatomical delineation, ...
Goubergrits Leonid L Biofluid Mechanics Laboratory, Charité-Universitätsmedizin, Berlin, Germany; Non-Invasive Cardiac Imaging in Congenital Heart Disease Unit, Charité-Universitätsmedizin, Berlin, and German Heart Institute, Berlin, - - 2014
To reduce the need for diagnostic catheterization and optimize treatment in a variety of congenital heart diseases, magnetic resonance imaging (MRI)-based computational fluid dynamics (CFD) is proposed. However, data about the accuracy of CFD in a clinical context are still sparse. To fill this gap, this study compares MRI-based CFD ...
Voultsinou Despoina - - 2014
A 40-year-old male presented with visuospatial processing disturbances. Family history was free. Conventional and advanced magnetic resonance imaging (MRI) studies were performed. On T2 and fluid attenuation inversion recovery images, an increased signal intensity extra-axial lesion was demonstrated. Post-contrast scans depicted homogeneous intense contrast medium enhancement. T2FNx01 star sequence was ...
Howells Fleur M FM Department of Psychiatry and Mental Health, Faculty of Health Sciences, University of Cape Town, South Africa. Electronic address: - - 2014
Methamphetamine (MA) use has been shown to decrease n-acetyl-aspartate (NAA), a marker of neuronal integrity and viability, on (1)H magnetic resonance spectroscopy ((1)H-MRS). However, little work has compared (1)H-MRS in MA dependent individuals and MA dependent individuals with MA induced psychotic disorder (MAP). Twenty six participants with MA dependence (sixteen ...
Donahue Manus J MJ 1] Department of Radiology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA [2] Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee, USA [3] Department of Neurology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA [4] Department of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee, - - 2014
Commonly used neuroimaging approaches in humans exploit hemodynamic or metabolic indicators of brain function. However, fundamental gaps remain in our ability to relate such hemo-metabolic reactivity to neurotransmission, with recent reports providing paradoxical information regarding the relationship among basal perfusion, functional imaging contrast, and neurotransmission in awake humans. Here, sequential ...
Li Kangan K Department of Radiology, Shanghai First People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, People's Republic of - - 2014
We report in vitro and in vivo magnetic resonance (MR) imaging of C6 glioma cells with a novel acetylated 3-aminopropyltrimethoxysilane (APTS)-coated iron oxide nanoparticles (Fe3O4 NPs). In the present study, APTS-coated Fe3O4 NPs were formed via a one-step hydrothermal approach and then chemically modified with acetic anhydride to generate surface ...
Padang Ratnasari - - 2013
Despite early repair, patients with aortic coarctation (CoA) continue to have a reduced life expectancy due to the development of late complications. We sought to define the rate of aortic abnormalities in patients with previous CoA repair, referred for surveillance magnetic resonance (MR) imaging. We evaluated 59 asymptomatic adults consecutively ...
Leite Ricardo André Amorim - - 2013
Objective To analyze the agreement rate of proton magnetic spectroscopy with magnetic resonance image (MRI) and surface electroence-phalography (EEG) in extratemporal neocortical epilepsies. Methods A cross-sectional study, type series of cases included 33 patients, age range 13-59 years old, of both gender, presenting structural alteration identified by MRI (75.8%) or ...
Hetherington Hoby P - - 2013
Up to 19% of veterans returning from the wars in Iraq and Afghanistan have a history of mild traumatic brain injury with 70% associated with blast exposure. Tragically, 20-50% of this group reports persistent symptoms, including memory loss. Unfortunately, routine clinical imaging is typically normal, making diagnosis and clinical management ...
Lee Hae-Ahm - - 2013
Rationale: Inhibition of histone deacetylases (HDAC) results in attenuated development of hypertension in DOCA-induced hypertensive rats and spontaneously hypertensive rats. However, the molecular mechanism remains elusive. Objective: We hypothesized that HDAC inhibition (HDACi) attenuates transcriptional activity of mineralocorticoid receptor (MR) through its acetylation and prevents development of hypertension in DOCA-induced ...
Solanki Guirish A - - 2013
Mucopolysaccharidosis IVA (MPS IVA), also known as Morquio-Brailsford or Morquio A syndrome, is a lysosomal storage disorder caused by a deficiency of the enzyme N-acetyl-galactosamine-6-sulphate sulphatase (GALNS). MPS IVA is multisystemic but manifests primarily as a progressive skeletal dysplasia. Spinal involvement is a major cause of morbidity and mortality in ...
Fayed Nicolás - - 2013
This work aimed to determine whether (1)H magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) are correlated with years of meditation and psychological variables in long-term Zen meditators compared to healthy non-meditator controls. Design. Controlled, cross-sectional study. Sample. Meditators were recruited from ...
Tafazoli Sharwin S Ahmanson-Lovelace Brain Mapping Center in the Department of Neurology, 660 Charles Young Dr. So. Los Angeles, CA 90095, - - 2013
Neuroimaging studies in multiple modalities have implicated the left or right dorsolateral prefrontal cortex (here, middle frontal gyrus) in attentional functions, in ADHD, and in dopamine agonist treatment of ADHD. The far lateral location of this cortex in the brain, however, has made it difficult to study with magnetic resonance ...
Lu Yu-Yu - - 2012
The purpose of the current study was to conduct a systematic review and meta-analysis of the published literature to evaluate the diagnostic accuracy of FDG PET or PET/CT for intramedullary and extramedullary lesions in multiple myeloma. The authors conducted a systematic MEDLINE search of published articles. Two reviewers independently assessed ...
Wang Ying - - 2012
Compression devices applied to the lower limb can help improve venous flow by deforming the muscles and veins. In this study, a two-dimensional finite element model using displacement boundary conditions was employed to simulate the deformations of deep veins in the calf under external compression. Magnetic resonance (MR) scans were ...
Kotsenas Amy L - - 2012
The role of the posterior elements in generating axial back and neck pain is well established; the imaging detection of posterior element pain generators remains problematic. Morphologic imaging findings have proved to be nonspecific and are frequently present in asymptomatic patients. Edema, inflammation, and hypervascularity are more specific for sites ...
Hsu Chijen - - 2012
The indications for cardiovascular implantable electronic devices (CIEDs) are ever expanding, seemingly in parallel to the similar widespread increase in the use of magnetic resonance imaging (MRI), where there are clear advantages of imaging with no ionizing radiation and superior tissue contrast. However, CIEDs have traditionally been considered an absolute ...
Wu Lian-Ming - - 2012
Background and Aim:  To obtain diagnostic performance values of diffusion-weighted magnetic resonance imaging (DWI) and fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography/compute tomography (PET/CT) in the detection of pancreatic malignancy. Methods:  We performed a meta-analysis of all available studies of the diagnostic performance of DWI and PET/CT for pancreatic malignancy. ...
Tang Qi - - 2012
The increasing magnetic strengths used for magnetic resonance imaging (MRI) combined with a greater number of MRI patients with cochlear implants (CIs) raises possible safety issues. This paper reviews the interactions between MRI and CI, and assesses MRI compatibility and safety of CIs at 0.2, 0.3, 1.0, 1.5 and 3.0 ...
Arndt Susan - - 2012
We describe for the first time localized necrotizing meningoencephalitis as the cause of functional hearing loss, facial nerve palsy, and vertigo after cochlear implant (CI) surgery. Magnet resonance imaging (MRI) and computed tomography scans before CI surgery and after 3 years showed no abnormalities, especially no evidence of a tumor ...
Cartwright Michael S MS Department of Neurology, Center for Worker Health, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA. - - 2012
To determine the prevalence of carpal tunnel syndrome (CTS) in Latino poultry-processing workers. Symptoms and nerve conduction studies were used to prospectively assess 287 Latino poultry-processing workers and 226 Latinos in other manual-labor occupations. The prevalence of CTS was higher in poultry-processing (8.7%) compared with nonpoultry manual workers (4.0%; P ...
Storandt Martha M Department of Psychology, Washington University, St. Louis, Missouri, - - 2012
Relations among antecedent biomarkers of Alzheimer disease (AD) were evaluated using causal modeling; although correlation cannot be equated to causation, causation does require correlation. Individuals aged 43 to 89 years (N = 220) enrolled as cognitively normal controls in longitudinal studies had clinical and psychometric assessment, structural magnetic resonance imaging ...
von Bodman Christian - - 2012
PURPOSE: We determined whether pelvic soft tissue and bony dimensions on endorectal magnetic resonance imaging influence the recovery of continence after radical prostatectomy, and whether adding significant magnetic resonance imaging variables to a statistical model improves the prediction of continence recovery. MATERIALS AND METHODS: Between 2001 and 2004, 967 men ...
Hasan Khader M KM Department of Diagnostic and Interventional Imaging, University of Texas Health Science Center at Houston, Houston, Texas, USA. - - 2012
To investigate the utility of multimodal quantitative MRI (qMRI) and atlas-based methods to identify characteristics of lesion-driven injury and neurodegeneration in relapsing remitting multiple sclerosis (RRMS). This work is health insurance portability and accountability act compliant. High resolution T1-weighted, dual echo, and fluid-attenuated inversion recovery and diffusion tensor MRI images ...
Yang Lei - - 2012
In China, dust samplers were originally designed to collect 'total dust' for a short term during production, which is different from the widely adopted sampling strategy for dust. With the aim to provide the conversion factor from Chinese total dust to US and German respirable dust and to look at ...
Shen Guangjian - - 2012
To observe the outcomes of 1H- MR-spectroscopy (MRS) guided gamma knife surgery for treatment of glioma. MATERIAL and Twenty patients with glioma diagnosed pathologically were randomly divided into MRI group and MRI plus MRS group. The target volume was defined as the tumor enhanced area plus the surrounding area with ...
Sotiriadis Alexandros - - 2011
OBJECTIVE: To systematically review published data on the neurodevelopment of children that were diagnosed prenatally with isolated agenesis of the corpus callosum. STUDY DESIGN: Medline and Scopus searches (1960-July 2011); cross-referencing of retrieved articles. RESULTS: Sixteen reports (132 cases of apparently isolated agenesis of the corpus callosum) were included in ...
Klement William - - 2011
OBJECTIVE: Using an automatic data-driven approach, this paper develops a prediction model that achieves more balanced performance (in terms of sensitivity and specificity) than the Canadian Assessment of Tomography for Childhood Head Injury (CATCH) rule, when predicting the need for computed tomography (CT) imaging of children after a minor head ...
Carmichael Owen O Department of Neurology, School of Medicine, University of California, Davis, Davis, CA, USA. - - 2012
Hippocampal injury in the Alzheimer's disease (AD) pathological process is region-specific and magnetic resonance imaging (MRI)-based measures of localized hippocampus (HP) atrophy are known to detect region-specific changes associated with clinical AD, but it is unclear whether these measures provide information that is independent of that already provided by measures ...
Barua Nilakshi - - 2011
In the present study antimycobacterial activity of a set of synthesized chalcone derivatives against Mycobacterium tuberculosis H37Rv were investigated by quantitative structure-activity relationship (QSAR) analysis using density functional theory (DFT) and molecular mechanics (MM+) based descriptors in both gas and solvent phases. The best molecular descriptors identified were hardness, E(HOMO) ...
Patil Anuja - - 2011
BACKGROUND: The purpose of this study was to determine the prevalence of carpal tunnel syndrome (CTS) among dairy workers. METHODS: Sixty-six dairy parlor workers and 58 non-parlor workers at dairies in Texas, New Mexico, and Colorado participated in structured interviews regarding demographics, work history, and hand symptoms. All participants had ...
Sano Kohei - - 2011
We aimed to establish a magnetic resonance imaging (MRI) protocol for the sensitive and specific imaging of functional molecules with a pre-targeting strategy utilizing the streptavidin-biotin interaction. Membrane type-1 matrix metalloproteinase (MT1-MMP) was selected as the target molecule. The biotinylated polyamidoamine dendrimer (PAMAM)-based contrast agent (Bt-PAMAM-DTPA(Gd)) was prepared, and its ...
Kenton Brian J - - 2011
The mechanical design of a high-bandwidth, short-range vertical positioning stage is described for integration with a commercial scanning probe microscope (SPM) for dual-stage actuation to significantly improve scanning performance. The vertical motion of the sample platform is driven by a stiff and compact piezo-stack actuator and guided by a novel ...
Yoo Jung-Wan - - 2011
To date, clinico-physiologic indices have not been compared with quantitative CT imaging indices in determining the risk of chronic obstructive pulmonary disease (COPD) exacerbation. We therefore compared clinico-physiologic and CT imaging indices as risk factors for COPD exacerbation in patients with COPD. We retrospectively analyzed 260 COPD patients from pulmonary ...
Murray Alison D - - 2011
The cognitive reserve hypothesis explains the disparity between clinical and pathological phenotypes and why, in two individuals with the same extent of neuropathology, one may be demented while the other remains cognitively intact. We examined the balance between brain magnetic resonance imaging measures of the two most common pathologies associated ...
Greene Sarah J - - 2011
Atrophy within the hippocampus (HP) as measured by magnetic resonance imaging (MRI) is a promising biomarker for the progression to Alzheimer's disease (AD). Subregions of the HP along the longitudinal axis have been found to demonstrate unique function, as well as undergo differential changes in the progression to AD. Little ...
Kayhanian Masoud - - 2012
This paper describes a study that used permeability measurement along with physical and hydrological characteristics of 20 pervious concrete pavements in parking lots throughout California. The permeability was measured at five locations: the main entrance, an area with no traffic, and three separate measurements within a parking space at each ...
Koutsouleris Nikolaos N Department of Psychiatry and Psychotherapy, Ludwig-Maximilian-University, Nussbaumstrasse 7, 80336 Munich, Germany. - - 2012
Reliable prognostic biomarkers are needed for the early recognition of psychosis. Recently, multivariate machine learning methods have demonstrated the feasibility to predict illness onset in clinically defined at-risk individuals using structural magnetic resonance imaging (MRI) data. However, it remains unclear whether these findings could be replicated in independent populations. We ...
Kim Kyung Ah - - 2011
PURPOSE: To determine whether peritumoral hypointensity seen on hepatobiliary phase images of preoperative gadoxetate disodium-enhanced magnetic resonance imaging (EOB-MRI) is useful for predicting microvascular invasion of hepatocellular carcinoma (HCC). MATERIALS AND METHODS: This study was approved by the Institutional Review Board. In all, 104 HCC masses in 104 patients who ...
Marchant Natalie L NL Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720, USA. - - 2012
The present study evaluated cerebrovascular disease (CVD), β-amyloid (Aβ), and cognition in clinically normal elderly adults. Fifty-four participants underwent magnetic resonance imaging (MRI), Pittsburgh compound B (PIB)-positron emission tomography (PET) imaging, and neuropsychological evaluation. High white matter hyperintensity burden and/or presence of infarct defined CVD status (CVD-: n = 27; ...
Roberts R Edward - - 2013
In recent years, diffusion-weighted magnetic resonance imaging (DW-MRI) has been increasingly used to explore the relationship between white matter structure and cognitive function. This technique uses the passive diffusion of water molecules to infer properties of the surrounding tissue. DW-MRI has been extensively employed to investigate how individual differences in ...
Sarro L - - 2011
BACKGROUND AND PURPOSE:ALS is predominantly a disease of the motor system, but cognitive and behavioral symptoms also are observed. DT MR imaging is sensitive to microstructural changes occurring in WM tracts of patients with ALS. In this study, we investigated the association between cognitive functions and extramotor WM tract abnormalities ...
Sormani M P - - 2011
In multiple sclerosis (MS), the aim of therapies is to prevent the accumulation of irreversible disability. This is difficult to assess given the short time course of clinical trials. MRI markers and relapses are often used as surrogate of disability in MS studies, but their validity remains controversial. We sought ...
Kaimal Vinod - - 2011
Nanovesicles composed of the phospholipid dioleylphosphatidylserine (DOPS) and a fusogenic protein, saposin C (SapC), selectively target and induce apoptotic cell death in a variety of human cancer cells in vitro and in vivo. We tested whether such tumor-homing nanovesicles are capable of delivering fluorescent probes and magnetic resonance (MR) contrast ...
Basu Sandip - - 2011
Increasingly, integrated positron emission tomography-computed tomography (PET/CT) imaging is playing a crucial role in the assessment of patients with known or suspected malignant pleural mesothelioma (MPM). Based on the data reported in the literature, this combined modality is likely to become the instrument of choice for examining patients of MPM. ...
Desikan Rahul S RS Department of Radiology, University of California-San Diego, La Jolla 92037, - - 2011
The relationship between neurodegeneration and the 2 hallmark proteins of Alzheimer's disease, amyloid-β (Aβ) and tau, is still unclear. Here, we examined 286 nondemented participants (107 cognitively normal older adults and 179 memory impaired individuals) who underwent longitudinal magnetic resonance (MR) imaging and lumbar puncture. Using mixed effects models, we ...
Grossman Elan J - - 2012
Conventional imaging is unable to detect damage that accounts for permanent cognitive impairment in patients with mild traumatic brain injury (mTBI). While diffusion tensor imaging (DTI) can help to detect diffuse axonal injury (DAI), it is a limited indicator of tissue complexity. It has also been suggested that the thalamus ...
Kitzler Hagen H HH Department of Neuroadiology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307 Dresden, Germany. - - 2012
Recent multiple sclerosis (MS) MRI research has highlighted the need to move beyond the lesion-centric view and to develop and validate new MR imaging strategies that quantify the invisible burden of disease in the brain and establish much more sensitive and specific surrogate markers of clinical disability. One of the ...
Langer Jill E - - 2011
To assess the impact of correlating findings from iodine I 123 (¹²³I) radionuclide scans and thyroid ultrasonography on the decision to perform fine-needle aspiration (FNA) biopsy of thyroid nodules. Iodine 123 scans and sonographic images of adult patients who had both examinations performed within 6 months of each other at ...
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