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Wu Ying Wei YW aDepartment of Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China Departments of bRadiology cPsychiatry, Mt. Sinai School of Medicine, New York, New York, - - 2014
We studied the effect of oxygen inhalation during resting state functional MRI scanning in healthy control individuals. We hypothesized that resting state networks would be modified under hyperoxic conditions. Thirty-four normal volunteers were recruited for this study. All participants were scanned twice: once while breathing atmospheric air and once under ...
Jiang H H Department of Stomatology, Chinese PLA General Hospital, Beijing, - - 2014
Chewing-side preference (CSP) may be associated with temporomandibular disorders. However, little information exists regarding whether CSP will lead to osseous changes of temporomandibular joint (TMJ) in asymptomatic participants. The aim of this study was to investigate the relationship between osseous morphology of TMJ in asymptomatic participants with CSP and without ...
Maksymowych Walter P WP From the Department of Medicine; Department of Radiology and Diagnostic Imaging, Spondyloarthritis Research Consortium of Canada (SPARCC) Center, University of Alberta, Edmonton, Alberta, Canada; the Department of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand; the Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, University of Copenhagen, Denmark. Supported by a research fellowship grant from the SPARCC and a grant from the Danish Council for Independent Research in the Medical Sciences to Dr. Pedersen. Dr. Maksymowych is a Medical Scientist of Alberta Innovates Health Solutions. W.P. Maksymowych, FRCP(C), Professor; S. Wichuk, BSc, Research Associate, Department of Medicine; R.G. Lambert, FRCP(C), Professor, Department of Radiology and Diagnostic Imaging, Spondyloarthritis Research Consortium of Canada Center, University of Alberta; P. Chiowchanwisawakit, MD, Department of Medicine, Siriraj Hospital, Mahidol University; S.J. Pedersen, MD, Rheumatologist, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, University of Copenhagen. Address correspondence to Dr. W.P. Maksymowych, Professor of Medicine, University of Alberta, 562 Heritage Medical Research Building, Edmonton, Alberta T6G 2S2, Canada. E-mail: walter.maksymowych@ualberta.ca. Accepted for publication September 2, - - 2014
There is an unmet need for reliable assessment of structural progression in the sacroiliac joints (SIJ) of patients with spondyloarthritis (SpA), but radiography is unreliable and lacks responsiveness. We aimed to develop and validate a new scoring method for structural lesions based on magnetic resonance imaging (MRI), the Spondyloarthritis Research ...
Esmaeili Amin A M.Sc. in Engineering Systems, Industrial and Manufacturing Engineering Department, Wichita State University, KS, - - 2014
To aid radiologists by measuring the carbon footprint of CT scans by quantifying in-hospital and out-of-hospital energy use and to assess public health impacts. The study followed a standard life cycle assessment protocol to measure energy from a CT scan then expanding to all hospital electrical energy related to CT ...
Coenen Adriaan A From the Departments of Radiology (A.C., M.M.L., A. Kurata, A.Kono, A.D., R.G.C., M.L.D., M.O., R.J.M.v.G, K.N.) and Cardiology (A.C., M.M.L., A.D., R.G.C., F.J.G., R.J.M.v.G., K.N.), Erasmus University Medical Center, 's-Gravendijkwal 230, Rotterdam 3015 CE, the - - 2014
Purpose To validate an on-site algorithm for computation of fractional flow reserve ( FFR fractional flow reserve ) from coronary computed tomographic (CT) angiography data against invasively measured FFR fractional flow reserve and to test its diagnostic performance as compared with that of coronary CT angiography. Materials and Methods The ...
Ann Soe Hee SH Division of Cardiology, Ulsan University Hospital, University of Ulsan College of Medicine, 290-3 Jeonha-dong, Dong-gu, Ulsan, 682-714, South - - 2014
Coronary artery calcium (CAC) measurement has been utilized as an important indicator of coronary artery disease and predictor of cardiovascular risk. The reproducibility of CAC measurements makes it clinically useful for the assessment of progression and regression of coronary atherosclerosis. This study assessed the reproducibility of the Agatston CAC score ...
Grosse Ulrich U From the *Diagnostic and Interventional Radiology, and †Section on Experimental Radiology, University Hospital Tuebingen; and ‡Department of Medical Oncology, Hematology and Rheumatology, Eberhard-Karls-University, Tübingen, - - 2014
On a 3-T magnetic resonance scanner, morphologic and perfusion changes of 9 patients with rheumatoid arthritis were evaluated after start of anti-interleukin 6 receptor antibody Tocilizumab (TCZ) treatment. Morphologic and perfusion-based magnetic resonance imaging (MRI) parameters were assessed before and 4, 12, and 24 after the start of TCZ treatment. ...
Chen Jennifer J Division of Trauma, Surgical Critical Care and Acute Care Surgery, Department of Surgery, Allegheny General Hospital, Pittsburgh, PA. Electronic address: - - 2014
Rib fractures (RIBFX) are a common injury and are associated with substantial morbidity and mortality. Using a previously published RIBFX scoring system, we sought to validate the system by applying it to a larger patient population. We hypothesized that the RIBFX scoring system reliably predicts morbidity and mortality in patients ...
Caputo Nicholas D ND From the Department of Emergency Medicine (N.D.C., C.S.), Lincoln Medical and Mental Health Center, Bronx; and Department of Emergency Medicine (G.L., K.S.), Icahn School of Medicine, Mount Sinai Hospital, New York, New - - 2014
Traumatic injury in the United States is the Number 1 cause of mortality for patients 1 year to 44 years of age. Studies suggest that early identification of major injury leads to better outcomes for patients. Imaging, such as computed tomography (CT), is routinely used to help determine the presence ...
Maqdes Ali A Hôpital Centre de Chirurgie Orthopédie et de la Main, 10 av Achille Baumann, 67400, Illkirch-Graffenstaden, France, - - 2014
The X index is a measure of the antero-inferior glenoid bone loss on unilateral 2D CT-scans in the preoperative analysis of chronic anterior shoulder instability. Recurrence rate was shown to be higher after stabilization surgery if X index is superior or equal to 0.4. The objective of this study was ...
Gent Yoony Y J YY From the Department of Rheumatology, Department of Radiology and Nuclear Medicine, Department of Clinical Epidemiology and Biostatistics, Vrije Universiteit University Medical Center; Department of Rheumatology, Jan van Breemen Research Institute/Reade, Amsterdam, the Netherlands. Y.Y.J. Gent, MD; A.E. Voskuyl, MD, PhD; C.J. van der Laken, MD, PhD, Department of Rheumatology; N. Ahmadi, MD; N. Hoetjes; C. van Kuijk, MD, PhD, Professor; O.S. Hoekstra, MD, PhD, Professor, Department of Radiology and Nuclear Medicine; M. Boers, MD, PhD, Professor, Department of Clinical Epidemiology and Biostatistics, VU University Medical Center; K. Britsemmer, MD; F. Turkstra, MD, PhD, Department of Rheumatology, Jan van Breemen Research Institute/Reade. Address correspondence to Dr. C.J. van der Laken, Department of Rheumatology, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands. E-mail: j.vanderlaken@vumc.nl. Accepted for publication July 24, - - 2014
To determine whether macrophage targeting by (R)-(11)C-PK11195 positron emission tomography (PET) can visualize subclinical joint inflammation in patients with rheumatoid arthritis (RA) without clinical arthritis during or after treatment, with flare as clinical outcome measure. (R)-(11)C-PK11195 PET and contrast-enhanced magnetic resonance imaging (MRI) of hands/wrists were performed in 29 patients ...
Runhaar J J Department of General Practice, Erasmus MC, University Medical Center, The Netherlands. Electronic address: - - 2014
Recently, the MRI Osteoarthritis Knee Score (MOAKS), a new semi-quantitative magnetic resonance imaging (MRI) scoring tool, was introduced by a panel of experienced researchers in osteoarthritis (OA). The MOAKS is primarily applicable to quantify OA status, since the interpretation of change in the MOAKS features was not described. In order ...
Wenham C Y J CY Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, UK; NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK. Electronic address: - - 2014
Sensitive biomarkers are needed to understand synovial response to therapy in osteoarthritis (OA). Dynamic, contrast-enhanced magnetic resonance imaging (DCE MRI) provides quantitative, novel measures of synovial inflammation. This exploratory study examined DCE-assessed synovial response to intra-articular corticosteroid (IACS). People with ACR clinical criteria OA knee underwent 3 T MRI pre- and ...
Klahr Paul P Philips Healthcare, ADI Business Unit, Cleveland, Ohio - - 2014
4D-CT can be performed using two acquisition modes. One employs a cine axial scan and the other acquires the data using a very low pitch helical acquisition. This study evaluates the longitudinal resolutions of each of these methods by creating slice sensitivity profiles (SSP). An SSP phantom was scanned using ...
Fujimoto E E Department of Orthopedic Surgery, Chugoku Rousai Hospital, 1-5-1 Hirotagaya, Kure, Hiroshima 737-0193, Japan. Electronic address: - - 2014
The purpose of this study was to analyze serial changes in the magnetic resonance imaging (MRI) signals of autograft hamstrings single bundle posterior cruciate ligament (PCL) reconstruction and the effects of remnant preservation (augmentation). Twenty-two isolated PCL injuries were arthroscopically reconstructed or augmented with hamstring tendons. MRI scans were obtained ...
McMahon Paul J PJ University of Pittsburgh Medical Center, Neurosurgery, Pittsburgh, Pennsylvania, United States ; - - 2014
Glial Fibrillary Acidic Protein and its breakdown products (GFAP-BDP) are brain specific proteins released into serum as part of the pathophysiologic response following traumatic brain injury (TBI). We performed a multicenter trial to validate and characterize the use of GFAP-BDP levels in the diagnosis of intracranial injury in a broad ...
Porcel José M - - 2014
Background:Chest computed tomography (CT) has become an integral part of the work-up for undiagnosed pleural effusions. We aimed to develop a CT scan-based scoring system for differentiating between benign and malignant pleural effusions. Methods:A number of chest CT abnormalities were compared between 228 patients with benign and 115 with malignant ...
Kim Hyun J HJ Center for Computer Vision and Imaging Biomarkers; Department of Radiological Science, David Geffen School of Medicine, UCLA, Los Angeles, California; Department of Biostatistics, Fielding School of Public Health, UCLA, Los Angeles, CA 90024. Electronic address: - - 2014
Median survival of patients with idiopathic pulmonary fibrosis (IPF) is 2-5 years. Sensitive imaging metrics can play a role in detecting early changes in therapeutic development. The aim of the present study was to compare known computed tomography (CT) histogram kurtosis and a classifier-based quantitative score to assess baseline severity and ...
He Mu M Center for In Vivo Microscopy, Duke University Medical Center, Durham, North - - 2014
Clinical deployment of hyperpolarized (129)Xe magnetic resonance imaging requires accurate quantification and visualization of the ventilation defect percentage (VDP). Here, we improve the robustness of our previous semiautomated analysis method to reduce operator dependence, correct for B1 inhomogeneity and vascular structures, and extend the analysis to display multiple intensity clusters. ...
Haugen Ida K IK Department of Rheumatology, Diakonhjemmet Hospital, Oslo, - - 2014
To examine whether MRI features predict radiographic progression including erosive evolution in patients from the Oslo hand osteoarthritis (OA) cohort, which is the first longitudinal hand OA study with available MRI. We included 74 patients (91% female, mean (SD) age of 67.9 (5.3) years) with MRI of the dominant hand ...
Gnannt Ralph R From the *Institute of Diagnostic and Interventional Radiology, and †Department of Surgery, Swiss Hepato-Pancreato-Biliary and Transplantation Center, University Hospital Zurich; and ‡Division of Biostatistics, Institute of Social and Preventive Medicine, University of Zurich, Zurich, - - 2014
Mortality from abdominal abscesses ranges from 30% in treated cases up to 80% to 100% in patients with undrained or nonoperated abscesses. Various computed tomographic (CT) imaging features have been suggested to indicate infection of postoperative abdominal fluid collections; however, features are nonspecific and substantial overlap between infected and noninfected ...
Morishita Y Y Department of Orthopedic Surgery, Spinal Injuries Center, Iizuka, - - 2014
Study Design:Retrospective clinical study.Objective:To elucidate the pathophysiology of rapid progressive clinical deterioration following the onset of cervical myelopathy.Setting:Spinal Injuries Center, Fukuoka, Japan.Methods:A total of 43 cervical spondylotic myelopathy (CSM) patients were treated surgically by a senior surgeon. All patients showed intramedullary intensity changes on magnetic resonance (MR) imaging. Overall, eight ...
Henry L - - 2014
The purpose of this study was to examine 3-month neuropsychological outcomes following mTBI (GCS 13-15) in participants with and without positive CT scans. 321 participants with mTBI (GCS score >12) from the prospective multicenter Transforming Research and Clinical Knowledge (TRACK-TBI) study were included in the current analyses, 44% of whom ...
Arliani Gustavo Gonçalves GG Centro de Traumatologia do Esporte (CETE), Departamento de Ortopedia e Traumatologia, Universidade Federal de São Paulo (UNIFESP/EPM-DOT), - - 2014
This study aims to compare the prevalence of osteoarthritis in two groups: one comprising former professional soccer players and the other comprising non-professional-athlete participants. Twenty-seven male former professional soccer players and 30 male volunteers from different non-sports professional areas participated in the study. All participants underwent bilateral knee radiography and ...
Igbinedion B O BO Radiology Department, College of Medical Sciences, University of Benin, Edo, - - 2014
AIMS AND OBJECTIVES The aim was to determine CT measured ocular biometry in Mid-Western Nigeria which may be employed on other Nigerians and Black Africans. PATIENTS AND METHODS The ocular images of 200 patients that had normal cranial CT scans without ocular abnormality or complaints were retrospectively retrieved and analysed. ...
Raj Rahul R 1Department of Neurosurgery, 2Department of Intensive Care, Helsinki University Hospital, - - 2014
Early computerized tomography (CT) abnormalities are important predictors of outcome after traumatic brain injury (TBI). To develop a novel CT scoring system ("Helsinki CT score") and compare it to the Marshall CT classification and the Rotterdam CT score in predicting long-term outcome of patients with TBI. 869 consecutive TBI patients ...
Calder Alistair D AD Radiology Department, Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London, WC1N 3JH, UK, - - 2014
Chest CT has been proposed as a surrogate outcome measure in the evaluation of cystic fibrosis lung disease. Quantitative evaluation of chest CT findings requires application of a scoring system to derive numerical values. Several scoring systems are in use. These mostly rely on a subjective judgement of the severity ...
Bryant Mark M Department of Diagnostic and Interventional Radiology, University of Heidelberg, Heidelberg, - - 2014
Distinct morphological emphysema phenotypes were assessed by CT to show characteristic perfusion defect patterns. Forty-one patients with severe emphysema (GOLD III/IV) underwent three-dimensional high resolution computed tomography (3D-HRCT) and contrast-enhanced magnetic resonance (MR) perfusion. 3D-HRCT data was visually analyzed for emphysema phenotyping and quantification by consensus of three experts in ...
Lashley Morgan J J O MJ Equine Veterinary Clinic 'De Raaphorst', Raaphorstlaan 18b, NL-2245 BG Wassenaar, The - - 2014
Among veterinary surgeons, interest has recently increased in the role of the horse's neck as a causative factor in complex locomotor disturbances. Specifically, controversy surrounds the trend for the head to be carried behind the vertical (BHV) in contravention of Fédération Equestre Internationale (FEI) rules. The aim of this study ...
Yamada Yoshitake Y Department of Diagnostic Radiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, - - 2014
Dual-energy CT technology enables acquisition of virtual unenhanced (VUE) images from contrast-enhanced scans. To assess the feasibility of coronary artery calcium (CAC) scoring on VUE images derived from fast kVp-switching dual-energy coronary CT angiography. Twenty-seven patients underwent true noncontrast CAC-scoring CT followed by routine single-energy (120-kVp) and fast kVp-switching dual-energy ...
Ahmed Wehab W Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, Postal zone 2300 RC, 2333 ZA, Leiden, The - - 2014
Potentially, Agatston coronary artery calcium (CAC) score could be calculated on contrast computed tomography coronary angiography (CTA). This will make a separate non-contrast CT scan superfluous. This study aims to assess the performance of a novel fully automatic algorithm to detect and quantify the Agatston CAC score in contrast CTA ...
Gupta Divya D Department of Otorhinolaryngology and Head and Neck Surgery, Maulana Azad Medical College and Associated Lok Nayak Hospital, 2, Bahadur Shah Zafar Marg, New Delhi-110002, India and - - 2014
The aim of the present study was to correlate olfactory dysfunction determined with psychophysical testing with nasal endoscopy, computed tomography (CT) scan, and patient's self-assessed olfactory deficit in patients of chronic rhinosinusitis (CRS) before and after sinus surgery. It was a prospective cohort study comprising of a total of 40 ...
Willemink Martin J MJ From the Departments of Radiology (M.J.W., R.A.P.T., T.L., R.P.J.B., A.M.R.S., P.A.d.J.) and Anatomy (R.L.A.W.B.), Utrecht University Medical Center, PO Box 85500, E01.132, 3508 GA Utrecht, the Netherlands; Department of Radiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands (R.V.); Department of Radiology, Maastricht University Medical Center, Maastricht, the Netherlands (M.D., J.E.W.); Department of Radiology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands (M.P.); and Department of Radiology, UZ Brussel, Brussels, Belgium (N.B., - - 2014
Purpose To determine the intervendor variability of Agatston scoring determined with state-of-the-art computed tomographic (CT) systems from the four major vendors in an ex vivo setup and to simulate the subsequent effects on cardiovascular risk reclassification in a large population-based cohort. Materials and Methods Research ethics board approval was not ...
Hsu Bailing B Nuclear Science and Engineering Institute, University of Missouri-Columbia, Columbia, MO, - - 2014
Conventional dual-head single photon emission computed tomography (SPECT)/CT systems capable of fast dynamic SPECT (DySPECT) imaging have a potential for flow quantitation. This study introduced a new method to quantify myocardial blood flow (MBF) and myocardial flow reserve (MFR) with DySPECT scan and evaluated the diagnostic performance of detecting coronary ...
Preti Antonio A Genneruxi Medical Center, Cagliari, Italy; IRCCS Centro San Giovanni di Dio-Fatebenefratelli, via Pilastroni 4, 20125 Brescia, - - 2014
The impact of alcohol on brain morphology was studied in a large group of cognitively intact people whose consumption of alcohol was below the threshold for abuse. Participants were 367 healthy subjects, aged 18 years or older, who underwent magnetic resonance imaging (MRI) for reasons other than cognitive impairment. MRI ...
Kumar Mohit M Supramolecular Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Jakkur P.O., Bangalore-560064 (India), Fax: - - 2014
Charge-transfer (CT) assemblies of aromatic donor (D) and acceptor (A) molecules have recently gained attention as a promising material for organic electronics and ferroelectrics. Two major factors which govern their functions are the strength of CT interaction and their supramolecular nanostructuring. Here we present coronene-naphthalenediimide (NDI)-based novel D-A pairs that ...
Shetty Abijit A Department of Urology, Medical Trust Hospital, Kochi, Kerala, - - 2014
Live donor nephrectomy has gained popularity on account of the laparoscopic technique, to overcome a small donor pool. Laparoscopic donor nephrectomy requires a precise study of the vascular and morphological renal anatomy, as laparoscopy is technically challenging due to the limited field of vision. In-depth knowledge of the renal anatomy ...
Malomo A O - - 2014
Eighty two (82) consecutive patients who presented with mechanical brain injury to the Accident and Emergency department of our hospital and were assessed with cranial Computerized Tomographic Scan between November 2005 and April 2006 were included in the study. Demographic data were obtained at admission. Clinical severity of head injury ...
Zhou Xiang-Xue XX Department of Neurology, The East Area of the First Affiliated Hospital, Guangzhou, - - 2014
The aim of this study was to evaluate the feasibility of characterizing the brain-mineral deposition in patients with Wilson disease (WD) using susceptibility-weighted imaging (SWI). The study enrolled 30 WD patients and 20 age-matched healthy controls. Neurological symptoms were scored using the modified Young Scale. The hepatic function indices, serum ...
Hahn Lewis D LD 1 Department of Radiology, Yale University School of Medicine, 333 Cedar St, New Haven, CT - - 2014
OBJECTIVE. The objective of our study was to catalog the anatomic features shown on preoperative CT that precluded living-donor liver donation. MATERIALS AND METHODS. We retrospectively reviewed the records of 159 consecutive candidates who were evaluated for potential right or left lobe liver donation from November 2007 to January 2012 ...
Chiang H-J HJ Liver Transplantation Program and Departments of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taiwan; Department of Medical Imaging and Radiological Sciences, College of Health Science, Kaohsiung Medical University, - - 2014
Hepatic steatosis can cause substantial problems for both donors and recipients in living donor liver transplantation (LDLT). The aim of this study is to evaluate the accuracy of the magnetic resonance IDEAL (iterative decomposition of water and fat with echo asymmetry and least squares estimation) sequence in quantifying the liver ...
Hou Dailun D Division of Computed Tomography, Department of Radiology, Shandong University School of Medicine, Thoracic Hospital, Shandong, China - - 2014
Background The aim of this study was to determine whether the diagnosis of intracranial tuberculosis (TB) can be improved when multi-slice computed tomography (MSCT) scans are taken with a 5-min delay after contrast media application. Material and Methods Pre- and post-contrast CT scans of the head were obtained from 30 ...
Xu Haotong H Postdoctoral Workstation, the General Surgery Center of the Peoples' Liberation Army, Chengdu Army General Hospital, Chengdu, Sichuan, P. R. China; Department of Radiology, Sichuan Provincial People's Hospital Supo, Chengdu, Sichuan, P. R. - - 2014
Because computed tomography (CT) has advantages for visualizing the manifestation of necrosis and local complications, a series of scoring systems based on CT manifestations have been developed for assessing the clinical outcomes of acute pancreatitis (AP), including the CT severity index (CTSI), modified CTSI, etc. Despite the internationally accepted CTSI ...
Medan Guy - - 2014
We present a new method for rigid registration of CT scans in Radon space. The inputs are the two 3D Radon transforms of the CT scans, one densely sampled and the other sparsely sampled. The output s the rigid transformation that best matches them. The algorithm starts by finding the ...
Klink T T Diagnostic, Interventional, and Pediatric Radiology, INSELSPITAL - Bern University Hospital, - - 2013
Purpose: To assess liver remnant volume regeneration and maintenance, and complications in the long-time follow-up of donors after living donor liver transplantation using CT and MRI. Materials and Methods: 47 donors with a mean age of 33.5 years who donated liver tissue for transplantation and who were available for follow-up ...
Dazzi Francisco Leôncio - - 2013
A crucial aspect of living-donor liver transplant is the risk imposed to the donor due to a procedure performed in a healthy individual that can lead to a high postoperative morbidity rate AIM: To correlate the pre- and intraoperative hepatic imaging findings of living adult donors. From 2003 to 2008 ...
Ragab Aly A University of Chicago Hospitals, - - 2013
A correct preoperative definition of the hepatic duct confluence anatomy of right liver living donors is a pivotal step in determining their candidacy for donation and planning the surgery. The purposes of this study are to evaluate the accuracy of three-dimensional Magnetic Resonance Cholangiography (3D MRCP) when compared with intraoperative ...
Segedi Maja M Department of Surgery, University of British Columbia, Vancouver, BC, Canada. - - 2013
The aim of the present study was to determine the utility of computed tomography (CT) and magnetic resonance imaging (MRI) anatomic mapping in the detection of biliary and vascular anomalies prior to a living liver donor (LLD) operation. A retrospective study of all LLD patient charts, operative and radiology reports ...
Danielsen Else R - - 2013
α-Mannosidosis, OMIM #248500, is an autosomal recessive lysosomal storage disease caused by acidic α-mannosidase deficiency. Treatment options include bone marrow transplantation (BMT) and, possibly in the future, enzyme replacement therapy. Brain magnetic resonance spectroscopy (MRS) enables non-invasive monitoring of cerebral treatment effect. Accumulated cerebral mannose-containing oligosaccharides were demonstrated by MRS ...
Bertagna Francesco - - 2012
Context:Thyroid incidentaloma diagnosed by 2-[18F]-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (F-18-FDG-PET/CT) is defined as a thyroid uptake incidentally and newly detected in a patient studied for nonthyroid purpose. In this review, we have comprehensively analyzed the diagnostic and clinical significance of F-18-FDG-PET/CT thyroid incidentalomas revealed during studies performed for an unrelated ...
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