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Koolen Bas B BB aDepartment of Nuclear Medicine, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands bDepartment of Nuclear Medicine, Hospital Clínic Barcelona, Barcelona cCorpuscular Physics Institute (IFIC), Valencia, - - 2014
The aim of the study was to evaluate the heterogeneity of primary tumor F-fluorodeoxyglucose (F-FDG) uptake in breast cancer patients using a dedicated breast PET. A positron emission tomography/computed tomography (PET/CT) of the thorax was performed 60 min after administration of 180-240 MBq of F-FDG in patients with breast cancer. ...
Liu Jianhua J Department of Radiology, The Second Hospital of Jilin University, Changchun, 130041 P. R. China. drliujh@yahoo.com Hanxueli6613@sina.cn - - 2014
Photothermal therapy, as a physical therapeutic technique to kill cancer, has generated a great deal of interest. Photothermal agents hence play a critical role in this modern therapy. We report the use of transition metal oxides as photothermal agents based on PEGylated WO3-x nanoparticles. The well-prepared nanoparticles presented effective results ...
You Xiao-Guang XG Department of Radiology and Cancer Institute, Hainan Medical College Hospital, Haikou City, Hainan Province, 570102, - - 2014
A new method for imaging the tumor human vascular endothelial growth factor 165 (VEGF 165) is presented. A magnetic resonance imaging (MRI) probe was prepared by crosslinking ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles to the aptamer for tumor vascular endothelial growth factor 165 (VEGF165-aptamer). The molecular probe was evaluated for ...
Liu Song S From the *Departments of Radiology, †Gastrointestinal Surgery, and ‡Gastroenterology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China; and §Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, - - 2014
The objective of our study was to assess the clinical feasibility of diffusion-weighted (DW) magnetic resonance (MR) imaging in preoperative T staging of gastric cancer prospectively. Forty-five patients underwent axial T2-weighted (T2W) and DW (b, 0 and 1000 seconds/mm) MR imaging. Two radiologists interpreted the images for detection and staging ...
Levine Benjamin D BD Department of Radiological Sciences, UCLA-Santa Monica Medical Center and Orthopedic Hospital, 1250 16th Street, Suite 2340, Santa Monica, CA, 90404, USA, - - 2014
Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) represents a rare subclassification of peripheral T-cell lymphoma (PTCL). We present a case of a 21-year-old female who presented with a 1-month history of pain in the left buttock and hip, tender left inguinal lymph nodes, fevers, and night sweats. Percutaneous core needle biopsy was ...
Murrone Domenico - - 2014
Cavernous hemangiomas are rare benign bone tumors and those at the level of the cranial bones are even rarer. A 50-year-old woman of Italian ethnicity presented with a frontal mass. A computed tomography scan showed an osteolytic lesion and a magnetic resonance imaging scan revealed a hypointense lesion on the ...
Liu Hui - - 2014
Development of novel nanomaterials-based contrast agents for targeted computed tomography (CT) imaging of tumors still remains a great challenge. Here we describe a novel approach to fabricating lactobionic acid (LA)-modified dendrimer-entrapped gold nanoparticles (LA-Au DENPs) for in vitro and in vivo targeted CT imaging of human hepatocellular carcinoma. In this ...
Zhang Shaomin S Departments of aRadiology bOncology, Shengjing Hospital of China Medical University, Shenyang cPhilips Healthcare, Beijing, - - 2014
The aim of the study was to determine the standardized uptake value (SUV) threshold on gross tumor volume from PET images (PET-GTV) that generates the maximal spatial overlap with MRI-defined GTV (MR-GTV) in locally advanced cervical cancer with the aid of hybrid PET/MRI. Twenty-seven patients with cervical carcinomas underwent F-FDG ...
Fathi Kazerooni Anahita A Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran, - - 2014
Glioblastoma multiforme (GBM) brain tumor is heterogeneous in nature, so its quantification depends on how to accurately segment different parts of the tumor, i.e. viable tumor, edema and necrosis. This procedure becomes more effective when metabolic and functional information, provided by physiological magnetic resonance (MR) imaging modalities, like diffusion-weighted-imaging (DWI) ...
Wang Wei W Department of Radiology, Fudan University Shanghai Cancer Center, Shanghai, PR - - 2014
Intraductal papilloma (IDP) is the most common pathological finding in women with pathological nipple discharge. Magnetic resonance imaging (MRI) has shown potential for characterizing breast tumors; however, MRI findings of IDPs are inconclusive, and certain diagnostic standards are lacking.Purpose: To characterize the MRI features of IDP from a relatively large ...
Mayerhoefer Marius E ME Department of Radiology and Nuclear Medicine, Medical University of - - 2014
To determine the value of diffusion-weighted magnetic resonance imaging (DWI-MRI) for pre-therapeutic imaging of fluorodeoxyglucose (FDG)-avid lymphoma and lymphoma with variable FDG-avidity. Treatment-naïve lymphoma patients that were referred for whole-body staging were included in this prospective study. Group A included patients with FDG-avid lymphoma (e.g., Hodgkin, diffuse large B-cell, and ...
Brodsky Michael C MC Departments of Ophthalmology (MCB) and Neurology (MCB, GFK), Mayo Clinic, Rochester, - - 2014
: We diagnosed chiasmal glioma in an 8-month-old infant who had spasmus nutans that spontaneously resolved. Magnetic resonance imaging showed no interval change in tumor size over the next 8 months. Clinical resolution of spasmus nutans does not preclude chiasmal glioma as the underlying cause.
An Lu L The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Normal University, Shanghai 200234, PR - - 2014
A series of hollow silica nanospheres (HSNSs) with sizes ranging from 100 to 400 nm were synthesized and used for primary ultrasound imaging (US) efficiency assessment. The 400 nm HSNSs were chosen as platform for conjugation with Gd-DTPA and cyclo-arginine-glycine-aspartic acid c(RGD) peptide to construct US and magnetic resonance imaging (MRI) dual-modal ...
Shah Muhammad M From the Division of Nuclear Medicine, Department of Radiology, Montefiore Medical Center and the Albert Einstein College of Medicine of Yeshiva University, Bronx, - - 2014
Retroperitoneal hemangioma is a rare but clinically significant condition that can be challenging to diagnose and characterize on anatomical imaging alone. We present a case of an 80-year-old woman with diabetes and hypertension, who was found to have an abdominal mass diagnosed first on CT abdomen and pelvis in March ...
Koyasu Sho S 1 Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, - - 2014
OBJECTIVE. The purpose of this study was to determine whether pretreatment quantitative and visual parameters seen on PET/CT using (18)F-FDG add prognostic information for clinical staging in patients with head and neck cancer. MATERIALS AND METHODS. We enrolled 108 patients with histologically proven oral, oropharyngeal, hypopharyngeal, and laryngeal squamous cell ...
Schieda Nicola N Department of Medical Imaging, The Ottawa Hospital, The University of Ottawa, 1053 Carling Avenue, Ottawa, Ontario, Canada, K1Y 4E9, - - 2014
Prostatic ductal adenocarcinoma (DCa) is an aggressive variant. The purpose of this study was to determine if T2 signal intensity (SI) differs from conventional adenocarcinoma (CCa). A retrospective study of patients who underwent preoperative MRI and prostatectomy between 2009 and 2012 was performed. T2 SI ratios (SIR) for tumour (T) ...
Liu Qiuming - - 2014
Presented in this paper is the preparation of a new theranostic vesicle which exhibits excellent in vitro and in vivo T1 magnetic resonance (MR) imaging contrast effect and good anticancer drug delivery ability. The theranostic vesicle has been easily prepared based on an amphiphilic biocompatible and biodegradable dibock copolymer, poly(ethyleneglycol)-block-poly(L-lactic-co-glycolic ...
Jeong Young Jin YJ Department of Nuclear Medicine, Dong-A University Medical Center, 1, 3ga, Dongdaesin-dong, Seo-gu, Busan, 602-715, South - - 2014
The aim of this study was to evaluate the clinical impact of the preoperative (18)F-FDG PET/CT in the initial workup of breast cancer with clinically negative axillary nodes. Whether the status of the clinical axillary nodal involvement can be considered a parameter for making a decision to omit the preoperative ...
Li Jia J Department of Ultrasound, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao tong University, Shanghai, PR China. Electronic address: - - 2014
The aim of this study was to characterize the ultrasound (US) and computed tomography (CT) findings of primary acinic cell carcinoma (AciCC) of the parotid gland. Seventy patients (70 lesions) with histopathologically proven AciCC underwent US or CT examination. The following characteristics were assessed on US images: size, shape, border, ...
Tanaka Yoko - - 2014
Myofibroma is a benign tumor composed of myoid spindle cells. The prevalence of myofibroma in the oral cavity is very low, with the mandible being the most common site. This report describes an adult case of myofibroma that arose on the mandible and includes magnetic resonance imaging (MRI) and positron ...
Song Le L From the Department of Nuclear Medicine, Peking University Third Hospital, Beijing, People's Republic of - - 2014
Solitary fibrous tumor of the liver was rarely documented. F-FDG PET/CT imaging of malignant hepatic solitary fibrous tumor in a 49-year-old male patient was reported. The multifocal hepatic lesions demonstrated avid FDG uptake. FDG PET/CT might be potentially useful in the differentiation of benign and malignant solitary fibrous tumor.
Wu Bin B Department of Radiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, - - 2014
Objectives: To study MR imaging diagnosis of ovarian fibrothecomas. Methods: MR imaging appearances of 27 ovarian fibrothecomas in 26 female patients confirmed by surgical pathology were retrospectively reviewed, and correlated with clinical and histological findings. Results: Most patients were postmenopausal women in 73.1% (19/26) of cases. 38.5% patients (10/26) showed ...
Kwee Sandi A SA The Queen's Medical Center, Honolulu, - - 2014
This study investigated the prognostic significance of metabolically active tumor volume (MATV) measurements applied to (18)F-fluorocholine PET/CT in castration-resistant prostate cancer (CRPC). (18)F-fluorocholine PET/CT imaging was performed on 30 patients with CRPC. Metastatic disease was quantified on the basis of maximum standardized uptake value (SUVmax), MATV, and total lesion activity ...
Andreano Anita A Center of Biostatistics for Clinical Epidemiology, Department of Health Sciences, University of Milano-Bicocca, Via Cadore 48, Monza, MB, 20900, - - 2014
To compare the diagnostic accuracy of dynamic contrast-enhanced (DCE) and diffusion-weighted (DW) MR imaging in detecting deep myometrial invasion in endometrial cancer, using surgical-pathological staging as reference standard. After searching a wide range of electronic databases and screening titles/abstracts, we obtained full papers for potentially eligible studies and evaluated according ...
Yu Jing J Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing, 100871, - - 2014
Fe5 C2 NPs exhibit a high contrast in magnetic resonance imaging (MRI), superior photoacoustic tomography improvements, and efficient photothermal therapy (PTT) due to their unique core/shell structure, with a magnetic core and carbon shell. By conjugating a new class of affinity proteins (ZHER2:342 ), they can target to tumor cells ...
Samén Erik - - 2014
Vascular endothelial growth factor receptor 2 (VEGFR2) is a crucial mediator of tumour angiogenesis. High expression levels of the receptor have been correlated to poor prognosis in cancer patients. Reliable imaging biomarkers for stratifying patients for anti-angiogenic therapy could therefore be valuable for increasing treatment success rates. The aim of ...
Andrulis Mindaugas M Institute of Pathology, University of Heidelberg, Heidelberg, - - 2014
To investigate how plasma cell infiltration patterns detected by MRI match the plasma cell distribution in bone marrow biopsy. We assessed 50 patients with monoclonal plasma cell disorders of all clinical stages. MRI infiltration pattern was compared with matched BM histology from the same anatomic region. MRI revealed a minimal ...
Yamada Ichiro I From the Departments of Diagnostic Radiology and Oncology (I.Y.), Pediatrics, Perinatal and Maternal Medicine (N.M.), Esophagogastric Surgery (T.K., Y.T.), and Pathology (E.I., D.K., Y.E.), Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan; Department of Physiology, Keio University School of Medicine, Tokyo, Japan (K.H., H.O.); and Central Institute for Experimental Animals, Kawasaki, Kanagawa, Japan - - 2014
Purpose To determine the feasibility of diffusion-tensor magnetic resonance (MR) imaging and tractography as a means of evaluating the depth of mural invasion by esophageal carcinomas. Materials and Methods This study was approved by the institutional review board, and written informed consent was obtained from each patient. Twenty esophageal specimens, ...
Caivano R R I.R.C.C.S. -C.R.O.B. , Rionero in Vulture (Pz) , Italy - - 2014
Purpose: Evaluate the role of diffusion-weighted-imaging (DWI) in the diagnosis and staging of gastric carcinoma. Materials and methods: A total of 31 patients with gastric adenocarcinoma, which underwent preoperative staging with 3Tesla Magnetic Resonance Imaging (MRI), were enrolled. Two radiologists evaluated the tumor staging in DWI. Results were compared to ...
Treglia Giorgio G From the *Department of Nuclear Medicine and PET/CT Center, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland; †Institute of Pathology, Locarno, Switzerland; and ‡Chair of Nuclear Medicine, University of Brescia and Spedali Civili di Brescia, Brescia, - - 2014
We report a case of squamous cell carcinoma of the tonsil incidentally detected by F-choline PET/CT. A 55-year-old male patient with a history of prostate cancer underwent F-choline PET/CT for restaging. PET/CT revealed a focal area of increased F-choline uptake corresponding to the left tonsil. No other areas of abnormal ...
Tanaka Kenichi K From the Departments of *Radiology, and †Otolaryngology, Faculty of Medicine, Kagawa University, Kagawa, - - 2014
Olfactory neuroblastoma is an uncommon malignant neoplasm of the superior nasal cavity. We report a case of a 78-year-old woman who presented with frontal headache and proptosis of the right eye. CT revealed a nasoethmoid mass with diffuse calcifications. FDG PET/CT demonstrated intense FDG uptake by a main nasoethmoid tumor ...
Muto Satoru S Department of Urology, Teikyo University School of Medicine, Tokyo, - - 2014
To investigate the clinical effectiveness of proton magnetic resonance spectroscopy in predicting local recurrence or residual disease after high-intensity focused ultrasound for treatment of localized prostate cancer. The present study included patients with localized prostate cancer who underwent high-intensity focused ultrasound of whole-gland ablation as primary therapy. Clinicopathological variables including ...
Parikh Jyoti J From the Departments of Radiology (J.P., H.V., V.G.), Clinical Oncology (J.G., A.T.), and Medical Oncology (J.M., M.H.), Guys and St Thomas' Hospitals NHS Foundation Trust, Westminster Bridge Road, London SE1 7EH, England; Division of Imaging Sciences and Biomedical Engineering, King's College, London, England (M.S., G.C., V.G.); and Institute of Nuclear Medicine, University College London, London, England - - 2014
Purpose To evaluate whether changes in magnetic resonance (MR) imaging heterogeneity may aid assessment for pathologic complete response (pCR) to neoadjuvant chemotherapy (NACT) in primary breast cancer and to compare pCR with standard Response Evaluation Criteria in Solid Tumors response. Materials and Methods Institutional review board approval, with waiver of ...
Aryal Santosh S Department of Translational Imaging, Houston Methodist Research Institute, Houston, TX, 77030, - - 2014
Hybrid PET/MRI scanners have the potential to provide fundamental molecular, cellular, and anatomic information essential for optimizing therapeutic and surgical interventions. However, their full utilization is currently limited by the lack of truly multi-modal contrast agents capable of exploiting the strengths of each modality. Here, we report on the development ...
Tahara Keiichiro K Department of Radiology, Kitakyushu Municipal Medical Center, 2-1-1 Bashaku, Kokurakita-ku, Kitakyushu, - - 2014
We report a rare case of crystal-storing histiocytosis (CSH) associated with marginal-zone lymphoma. A 91-year-old woman with a history of breast cancer presented with masses of the posterior neck, right breast, and left upper arm. An enlarging mass of the neck was removed and was histologically diagnosed as CSH, associated ...
Ippolito Davide D Department of Diagnostic Radiology, University of Milano-Bicocca, Milan, Italy, - - 2014
To assess the diagnostic value of dynamic contrast-enhanced (DCE) perfusion-magnetic resonance imaging (MRI) in detection, characterization and grading of endometrial cancer, using histopathological analysis as the standard of reference. Eighty patients with histologically proven endometrial carcinoma who underwent MRI (1.5 T magnet) of the pelvis for staging purposes were enrolled in ...
Tsuboyama Takahiro T From the Departments of *Radiology, †Pathology, and ‡Nuclear Medicine, Osaka University Graduate School of Medicine, Osaka, - - 2014
The objectives of this study were to correlate fluorodeoxyglucose uptake in ovarian masses on positron emission tomography/computed tomography (PET/CT) with pathological grades of malignancy and subtypes and to determine the appropriate approach for combining PET/CT and contrast-enhanced magnetic resonance imaging (CE-MRI) to characterize ovarian masses. A retrospective study was conducted ...
Reiner Caecilia S CS Institute of Diagnostic and Interventional Radiology (C.S.R., F.M., G.P., T.P., H.A.). Electronic address: - - 2014
To evaluate computed tomography (CT) perfusion for assessment of early treatment response after transarterial radioembolization of patients with liver malignancy. Dynamic contrast-enhanced CT liver perfusion was performed before and 4 weeks after transarterial radioembolization in 40 patients (25 men and 15 women; mean age, 64 y ± 11; range, 35-80 ...
Pallone Matthew J MJ Thayer School of Engineering, Dartmouth College, Hanover, NH, - - 2014
Wire localization for excision of nonpalpable breast cancer is an inefficient and inexact technique. A total of 18 women with palpable invasive breast cancers underwent preoperative prone and supine magnetic resonance imaging (MRI). Intraoperatively, the edges of the tumor were palpated and marked on the skin surface. The breast was ...
Doll C C Radiation Oncology Department, University Medical Center Freiburg, Robert-Koch-Str. 3, 79106, Freiburg/Breisgau, - - 2014
The integration of positron emission tomography (PET) information for target volume delineation in radiation treatment planning is routine in many centers. In contrast to automatic contouring, research on visual-manual delineation is scarce. The present study investigates the dependency of manual delineation on experience and qualification. A total of 44 international ...
Chuang Yao-Chen YC Department of Biological Science and Technology, Institute of Molecular Medicine and Bioengineering, National Chiao Tung University, 75 Bo-Ai Street, Hsinchu 30068, - - 2014
A novel dual functional theranosis platform is developed based on manganese magnetism-engineered iron oxide (MnMEIO) and gold nanorods (AuNRs) to combine magnetic resonance (MR) imaging and photothermal therapy in one nanocluster. The platform showed improved T2-weighted MR imaging and exhibited a near-infrared (NIR) induced temperature elevation due to the unique ...
Watanabe Shinya S Department of Neurosurgery, Faculty of Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, 305-8575, - - 2014
Due to the rarity of skull Langerhans cell histiocytosis (LCH), correlations between abnormalities on magnetic resonance imaging (MRI) and pathological findings have not been fully evaluated. Only a few reports have as yet compared MRI of LCH infiltration and histological diagnostic features. A 22-year-old man with an unremarkable past medical ...
Hammond E M EM The Gray Institute for Radiation Oncology and Biology, Department of Oncology, University of Oxford, Oxford, - - 2014
Hypoxia was identified as a microenvironmental component of solid tumours over 60 years ago and was immediately recognised as a potential barrier to therapy through the reliance of radiotherapy on oxygen to elicit maximal cytotoxicity. Over the last two decades both clinical and experimental studies have markedly enhanced our understanding ...
Wu Guang-Yu GY Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, No. 1630, Dongfang Road, Pudong, Shanghai 200120, PR - - 2014
To evaluate the performance of computed tomographic urography (CTU), static-fluid magnetic resonance urography (static-fluid MRU) and combinations of CTU, static-fluid MRU and diffusion weighted imaging (DWI) in the diagnosis of upper urinary tract cancer. Between January 2010 and June 2011, patients with suspected UUT cancer underwent CTU, static-fluid MRU and ...
Yesuratnam A A Department of Radiology, The Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, - - 2014
The aim of this study was to investigate the correlation between tumour thickness (TT) on intraoral ultrasound (US) and magnetic resonance imaging (MRI) with the histologically determined TT of tongue cancers. Secondary objectives included evaluation of potential confounders that affect this association and the predictive value for simultaneous neck dissection. ...
Zhao Ri-Sheng RS 1Department of Colorectal Surgery, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China 2Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China 3School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China 4Department of Surgery, University of Michigan, Ann Arbor, - - 2014
Magnetic resonance imaging and endoluminal ultrasound play an important role in the restaging of locally advanced rectal cancer after preoperative chemoradiotherapy, yet their diagnostic accuracy is still controversial. Meta-analysis was performed to estimate the diagnostic performance of MRI and endoluminal ultrasound. Electronic databases from 1996 to March 2012 were searched. ...
Sporea Ioan I Department of Gastroenterology and Hepatology, "Victor Babeș" University of Medicine and Pharmacy Timișoara, - - 2014
Abdominal ultrasound is one of the most popular imaging methods due to its feasibility, low cost and accessibility. Contrast Enhanced Ultrasound (CEUS) with second generation contrast agents became in the last years a useful tool for the characterization of focal liver lesions (FLL) so that EFSUMB issued guidelines for its ...
Kajiwara Takeshi T Department of Gastroenterology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Ehime 791-0280, - - 2014
Positron emission tomography/computed tomography (PET/CT) with (18)F-fluoro-2-deoxyglucose (FDG-PET/CT) has become established in cancer imaging, and derived maximum standardized uptake values (SUVmax) add functional information regarding cancer, including esophageal squamous cell carcinoma (ESCC). The aim of the present study was to determine the clinical significance and association of tumor progression using ...
Saklani Avanish P AP Avanish P Saklani, Sung Uk Bae, Nam Kyu Kim, Section of Colon and Rectal Surgery, Department of Surgery, Yonsei University College of Medicine, Seoul 120527, South - - 2014
Magnetic resonance imaging (MRI) in rectal cancer was first investigated in 1999 and has become almost mandatory in planning rectal cancer treatment. MRI has a high accuracy in predicting circumferential resection margin involvement and is used to plan neoadjuvant therapy. The accuracy of MRI in assessing mesorectal lymph nodes remains ...
Filss Christian P CP Institute of Neuroscience and Medicine (INM-3, -4, -5), Research Center Jülich, Jülich, - - 2014
PET using O-(2-(18)F-fluoroethyl)-l-tyrosine ((18)F-FET) provides important diagnostic information in addition to that from conventional MR imaging on tumor extent and activity of cerebral gliomas. Recent studies suggest that perfusion-weighted MR imaging (PWI), especially maps of regional cerebral blood volume (rCBV), may provide similar diagnostic information. In this study, we directly ...
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