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Rootman Jack J *Department of Ophthalmology and Visual Sciences, †Department of Pathology and Laboratory Medicine, and ‡Department of Radiology, University of British Columbia and the Vancouver General Hospital, Vancouver, British Columbia, - - 2014
To describe the authors' experience with orbital vascular malformations using the International Society for the Study of Vascular Anomalies (ISSVA) classification and the preferred radiologic techniques. Review of clinical and radiologic experience from 1976 to 2012. This article presents the findings from several studies conducted on vascular malformations of the ...
Jeong Jin Hyeok JH Department of Otolaryngology-Head and Neck Surgery, College of Medicine, Hanyang University, Seoul, - - 2014
The ciliary epithelial cells in the paranasal sinuses produce nasal nitric oxide (NO) continuously and plays a variety of roles in the paranasal sinuses. The purpose of this study was to assess whether we can use the levels of nasal NO (nNO) and exhaled NO (eNO) as a tool for ...
Friel Michael T - - 2013
Patients with unilateral cleft lip and palate (CLP) deformities commonly develop nasal airway obstruction, necessitating septoplasty at the time of definitive rhinoplasty. We assessed the contribution of the bony septum to airway obstruction using computed tomography (CT) and cone beam CT (CBCT). A 2-year retrospective review of all subjects with ...
Svenningsen Sarah - - 2013
Hyperpolarised (3)He MRI provides a way to visualise regional pulmonary functional abnormalities that in asthma are thought to be related to airway morphological abnormalities. However, the exact aetiology of ventilation defects in asthma is not well understood. To better understand the determinants of ventilation defects in asthma, we evaluated well-established ...
Connes Philippe - - 2013
Cerebral vasculopathy is the most severe complication to affect children with sickle cell anaemia and its pathophysiology is complex. Traditionally, small-vessel occlusion by intravascular sickling and sludging was considered to underlie the strokes but, in the last 20 years, progressive major cerebral vessel involvement has become recognized as the principal responsible ...
Guo Jun - - 2012
The marginal delineation of gliomas cannot be defined by conventional imaging due to their infiltrative growth pattern. Here we investigate the relationship between changes in glioma metabolism by proton magnetic resonance spectroscopic imaging ((1)H-MRSI) and histopathological findings in order to determine an optimal threshold value of choline/N-acetyl-aspartate (Cho/NAA) that can ...
Oka Hidehiro - - 2012
We describe the clinicopathological features of 25 brainstem gliomas (BSGs). Twenty BSGs located in the pons and were all in children. Four BSGs located in the medulla oblongata were in 2 children and 2 adults. One (in a child) was located in the midbrain. Radiological findings on MR images were ...
Miyazaki Mitsue - - 2012
Until recently, time-of-flight (TOF) and phase contrast (PC) were the only non-contrast MR angiography (NC-MRA) techniques practically used in clinical. In the decade, NC-MRA have been gained a revival of an interest among the MR researchers and scientists, in part because of safety concerns related to the possible link between ...
Smits Marion - - 2012
Smits M, Visch-Brink EG, van de Sandt-Koenderman ME, van der Lugt A. Advanced magnetic resonance neuroimaging of language function recovery after aphasic stroke: a technical review. Arch Phys Med Rehabil 2012;93(1 Suppl 1):S4-14. Two advanced magnetic resonance neuroimaging techniques, functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI), have ...
Degnan Andrew J - - 2012
Managing asymptomatic carotid atherosclerosis with a view to preventing ischemic stroke is a challenging task. As the annual risk of stroke in untreated asymptomatic patients on average is less than the risk of surgical intervention, the key question is how to identify those asymptomatic individuals whose risk of stroke is ...
Miyazaki Mitsue - - 2012
Until recently, time-of-flight (TOF) and phase contrast (PC) were the only non-contrast MR angiography (NC-MRA) techniques practically used in clinical. In the decade, NC-MRA have been gained a revival of an interest among the MR researchers and scientists, in part because of safety concerns related to the possible link between ...
Blankholm Anne Dorte - - 2012
Non-contrast-enhanced magnetic resonance angiography has gained renewed interest since the discovery of the association between gadolinium-based contrast agents and nephrogenic systemic fibrosis. The following article is an overview of the different magnetic resonance angiography sequences, the technical possibilities and new developments. Clinical options and recent advancements will be highlighted, and ...
Hoeffner E G - - 2011
SUMMARY:The beginning of neuroradiology can be traced to the early 1900s with the use of skull radiographs. Ventriculography and pneumoencephalography were introduced in 1918 and 1919, respectively, and carotid angiography, in 1927. Technical advances were made in these procedures during the next 40 years that lead to improved diagnosis of ...
Sun X - - 2011
Magnetic nanoparticles (MNPs) have been studied widely as a powerful diagnostic probe and therapeutic agent for biomedical applications. In recent years, they are also found to be sensitive to magnetoresistive (MR) devices and MNP-MR biochips are predicted to be more affordable, portable and sensitive than the conventional optical detection methods. ...
Sharp David J DJ The Computational, Cognitive and Clinical Neuroimaging Laboratory, The Division of Experimental Medicine, The Centre for Neuroscience, Imperial College London, Hammersmith Hospital Campus, London, UK. - - 2011
Traumatic brain injury (TBI) often results in traumatic axonal injury (TAI). This is difficult to identify using conventional neuroimaging methods. We review recent work that uses advanced imaging methods to identify TAI following mild (m)TBI. Susceptibility-weighted imaging (SWI) is a highly sensitive way of identifying microbleeds, which are a marker ...
Hulvershorn Leslie A LA Mood and Emotional Disorders Across the Lifespan Center, Department of Psychiatry, Indiana University School of Medicine, Indianapolis, IN, USA. - - 2011
Child and adolescent psychiatric neuroimaging research typically lags behind similar advances in adult disorders. While the pediatric depression imaging literature is less developed, a recent surge in interest has created the need for a synthetic review of this work. Major findings from pediatric volumetric and functional magnetic resonance imaging (fMRI), ...
Lederlin Mathieu - - 2011
Coronary artery imaging in children is challenging, with high demands both on temporal and spatial resolution due to high heart rates and smaller anatomy. Although invasive conventional coronary angiography remains the benchmark technique, over the past 10 years, CT and MRI have emerged in the field of coronary imaging. The choice ...
Shapiro L M LM Department of Radiology, Stanford University, Stanford, CA 94305, - - 2012
Conventional, static magnetic resonance imaging (MRI) is able to provide a vast amount of information regarding the anatomy and pathology of the musculoskeletal system. However, patients, especially those whose pain is position dependent or elucidated by movement, may benefit from more advanced imaging techniques that allow for the acquisition of ...
Stoop Esther M - - 2012
Screening for colorectal cancer is widely recommended, but the preferred strategy remains unidentified. We aimed to compare participation and diagnostic yield between screening with colonoscopy and with non-cathartic CT colonography. Members of the general population, aged 50-75 years, and living in the regions of Amsterdam or Rotterdam, identified via the ...
Dijkhuizen Rick M RM Biomedical MR Imaging and Spectroscopy Group, Image Sciences Institute, University Medical Center Utrecht, Building Nieuw Gildestein, Yalelaan 2, 3584 CM Utrecht, The - - 2011
Traumatic brain injury is a heterogeneous and multifaceted neurological disorder that involves diverse pathophysiological pathways and mechanisms. Thorough characterization and monitoring of the brain's status after neurotrauma is therefore highly complicated. Magnetic resonance imaging (MRI) provides a versatile tool for in vivo spatiotemporal assessment of various aspects of central nervous ...
Morató-López A E - - 2011
The urachal mucinous adenocarcinoma is a rare malignant neoplasm located between the bladder and the umbilicus. It is usually found in an advanced stage at the moment of diagnosis. We have analyzed a clinical case in which the PET-CT study provided valuable morphological and metabolic information for diagnosis and staging.
Costa Flávia Martins - - 2011
Magnetic resonance (MR) imaging is an important modality for the preoperative and posttreatment evaluation of musculoskeletal tumors. In some cases, MR imaging is unable to offer information about the extension of tumoral necrosis and the presence of viable cells. Advanced MR imaging techniques are now used in association with conventional ...
Dvorak Ryan A - - 2011
Nuclear medicine has long played an important role in the noninvasive evaluation of known or suspected coronary artery disease. The development of single photon emission computed tomography (SPECT) led to improved assessments of myocardial perfusion, and the use of electrocardiographic gating made accurate measurements of ventricular wall motion, ejection fractions, ...
Webb Andrew - - 2011
Nuclear magnetic resonance and magnetic resonance imaging are two of the most important techniques in analytical chemistry and non-invasive medical imaging, respectively. They share a common physical basis, one aspect of which is a low intrinsic sensitivity relative to complementary techniques. Encouragingly, recent advances in physics, chemistry, engineering and data ...
Falk Erling - - 2011
The High-Risk Plaque (HRP) Initiative is a research and development effort to advance the understanding, recognition, and management of asymptomatic individuals at risk for a near-term atherothrombotic event such as myocardial infarction or stroke. Clinical studies using the newest technologies have been initiated, including the BioImage Study in which novel ...
Degnan A J - - 2011
SUMMARY:Intracranial atherosclerotic disease may constitute the most common cause of ischemic stroke worldwide; yet, in the developed world, imaging research has largely focused on extracranial atherosclerosis. Many studies in populations of Asian, African, and Hispanic descent demonstrate the preponderance of intracranial stenosis compared with carotid stenosis. This review examines the ...
Pula John H - - 2011
PURPOSE OF REVIEW: Radiologic imaging is indispensible for the diagnosis and management of many neuro-ophthalmologic conditions. Advances in the radioimaging of neuro-ophthalmologic disorders may evolve from the clinical or the radiological side, meaning there is a constant stream of new information for the clinician. RECENT FINDINGS: Functional MRI, diffusion tensor ...
Bulas Dorothy - - 2011
Advances in high-resolution prenatal ultrasound and fetal magnetic resonance (MR) imaging have changed the practice of obstetrics by allowing better visualization of intrathoracic and neck structures and better estimation of lung volumes. More accurate prenatal diagnosis has increased options for pregnancy management and treatment, delivery planning, and postnatal care. Anyone ...
Bailey Thomas M - - 2011
Cumulative patient radiation dose is a hot topic making headlines today. Responsible for almost two thirds of the medical radiation dose given to patients, computed tomography (CT) has been the major target of these news articles. Through this review of peer reviewed publications, an examination of the relationship between the ...
Chaudhary Vikas - - 2011
Pituitary lesions, albeit relatively infrequent, can significantly alter the quality of life. This article highlights the role of advanced imaging modalities in evaluating pituitary-hypothalamic axis lesions. Magnetic resonance imaging (MRI) is the examination of choice for evaluating hypothalamic-pituitary-related endocrine diseases. Advanced MR techniques discussed in this article include dynamic contrast-enhanced ...
Petrirena Gregorio J - - 2011
PURPOSE OF REVIEW: To highlight the most recent advances in PET imaging of brain tumors, aiming at expanding the referring physician's knowledge in the field, the sine qua non for translating PET into the practice of neuro-oncology. RECENT FINDINGS: The role of PET with amino acid tracers in the setting ...
Hutton Brian F - - 2011
Abstract Statistical iterative reconstruction is now widely used in clinical practice and has contributed to significant improvement in image quality in recent years. Although primarily used for reconstruction in emission tomography (both single photon emission computed tomography (SPECT) and positron emission tomography (PET)) there is increasing interest in also applying ...
Quaranta-Leoni Francesco M - - 2011
PURPOSE OF REVIEW: The introduction of hydrogel socket and orbital expanders has modified the approach towards the rehabilitation of congenital anophthalmia. This study highlights the most recent advances for the treatment of congenital anophthalmia based on personal experience and the review of recent literature. RECENT FINDINGS: Hydrogel socket expanders may ...
Rice Samuel L - - 2011
Although (18)F-fluorodeoxyglucose ((18)F-FDG) is still the most widely used positron emission tomography (PET) radiotracer, there are a few well-known limitations to its use. The last decade has seen the development of new PET probes for in vivo visualization of specific molecular targets, along with important technical advances in the production ...
Sinha Rakesh - - 2011
In recent years, advances in scanner technology and competition from other specialties have produced rapid changes in the way the intestines are imaged. MRI and CT scan along with the traditional enteroclysis examination have emerged at the forefront of intestinal imaging. Functional modalities such as diffusion and perfusion imaging are ...
Castaneda Rosalinda T - - 2011
BACKGROUND: Human embryonic stem cells (hESC) can generate cardiomyocytes (CM), which offer promising treatments for cardiomyopathies in children. However, challenges for clinical translation result from loss of transplanted cell from target sites and high cell death. An imaging technique that noninvasively and repetitively monitors transplanted hESC-CM could guide improvements in ...
Bäuerle Tobias - - 2011
The aim of this study was to investigate the effect of inhibiting α(v) β(3) /α(v) β(5) integrins by cilengitide in experimentally induced breast cancer bone metastases using noninvasive imaging techniques. For this purpose, nude rats bearing established breast cancer bone metastases were treated with cilengitide, a small molecule inhibitor of ...
Zhang Jian - - 2011
Although limbic structure changes have been found in chronic and recent onset post-traumatic stress disorder (PTSD) patients, there are few studies about brain structure changes in recent onset PTSD patients after a single extreme and prolonged trauma. In the current study, 20 coal mine flood disaster survivors underwent magnetic resonance ...
Park Hee Myung - - 2011
Magnetic resonance electrical impedance tomography (MREIT) has been introduced as a non-invasive modality to visualize the internal conductivity and/or current density of an electrically conductive object by the injection of current. In order to measure a magnetic flux density signal in MREIT, the phase difference approach in an interleaved encoding ...
Saito Anneyuko I - - 2011
OBJECTIVE: Using 5-bulk-density heterogeneous dose calculation, we investigated whether contrast-enhanced (CE+) computed tomography (CT) will affect dose-calculation accuracy in the thoracic area. METHODS: We analyzed 17 radiation-oncology patients who underwent thoracic CE+ CTs. Full-resolution CT and 5-bulk-density plans were generated using an adaptive convolution algorithm. Bulk densities for air, lung, ...
Matsusaki Shimpei - - 2011
A 72-year-old man was admitted to our hospital for further investigation of pancreatic mass. Ultrasonography revealed hypoechoic mass with hyperechoic and aechoic area. Contrast enhanced ultrasonography (CE-US) revealed a vascular image in the lesion. CT showed some enhanced parts of low density mass in the pancreatic body, which was recognized ...
Lambert Jonathan - - 2011
Dose planning requires a CT scan which provides the electron density distribution for dose calculation. MR provides superior soft tissue contrast compared to CT and the use of MR-alone for prostate planning would provide further benefits such as lower cost to the patient. This study compares the accuracy of MR-alone ...
Hayashi Kensei - - 2011
AIM: To differentiate between solid serous cystadenoma (SSCA) and endocrine tumor (ET) of the pancreas using dynamic CT findings. MATERIALS AND METHODS: Between 2001 and 2008, there were 3 SSCA and 15 ET surgically resected in our institute, for whom preoperative multidetector-row CT were available. Various CT features were retrospectively ...
Yamashiro Tsuneo - - 2011
The aim of this study is to evaluate the relationship between lung function and kurtosis or skewness of lung density histograms on computed tomography (CT) in smokers. Forty-six smokers (age range 46?81 years), enrolled in the Lung Tissue Research Consortium, underwent pulmonary function tests (PFT) and chest CT at full ...
Sriram Renuka - - 2011
Coronary disease risk increases inversely with high-density lipoprotein (HDL) level. The measurement of the biodistribution and clearance of HDL in vivo, however, has posed a technical challenge. This study presents an approach to the development of a lipoprotein MRI agent by linking gadolinium methanethiosulfonate (Gd[MTS-ADO3A]) to a selective cysteine mutation ...
Schlemmer H-P - - 2011
Radiotherapy has been considerably improved by three-dimensional intensity-modulated radiation therapy (imRT). The technique of dose painting affords precise adaption of the dose distribution to the complex geometry of the tumor including an improved block out of surrounding healthy structures. Progress in image-guided radiotherapy enables tracking of tumor and healthy organs ...
Liu Guanshu - - 2011
In recent years, several reporter genes have been designed for non-invasive magnetic resonance imaging (MRI). Here, we offer a brief summary of recent advances in MRI reporter gene technology, as well as elaborated protocols for cloning, expression, and imaging of reporter genes based on a chemical exchange saturation transfer (CEST) ...
Hogers Bianca - - 2011
Non-invasive imaging of embryonic development has been an ultimate goal for embryologists for many years. Due to advances in MRI hardware and software, the extremely high spatial resolution necessary to study embryos can now be obtained. Fixed embryos can be scanned to visualize the complex 3D morphology of the developing ...
Baranova Ancha - - 2011
With great advancements in the therapeutic modalities used for the treatment of chronic liver diseases, the accurate assessment of liver fibrosis is a vital need for successful individualized management of disease activity in patients. The lack of accurate, reproducible and easily applied methods for fibrosis assessment has been the major ...
Sakata Naoaki - - 2010
BACKGROUNS/AIMS: There are few studies about the assessment of pancreatic function using computed tomography (CT) volumetry. In this study, we examined the correlation between CT volumetry and endocrine parameters (blood glucose and HbA1c) of the pancreas. METHODS: A total of 68 patients underwent enhanced CT for pancreatic disease from January ...
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