Search Results
Results 1 - 50 of 2687
1 2 3 4 5 6 7 8 9 10 >
Mykhaylyk Olga O Institute of Experimental Oncology, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Strasse 22, Munich, 81675, Germany, - - 2015
This chapter describes how to design and conduct experiments to deliver siRNA to adherent cell cultures in vitro by magnetic force-assisted transfection using self-assembled complexes of small interfering RNA (siRNA) and cationic lipids or polymers that are associated with magnetic nanoparticles (MNPs). These magnetic complexes are targeted to the cell ...
Georgiadis Andrew G AG Department of Orthopaedic Surgery, Henry Ford Hospital, Detroit, MI, - - 2014
The terms "femoral anteversion" and "femoral torsion" have often been used interchangeably in the orthopaedic literature, yet they represent distinct anatomical entities. Anteversion refers to anterior tilt of the femoral neck, whereas torsion describes rotation of the femoral shaft. Together, these and other transverse plane differences describe what may be ...
Abedini-Nassab Roozbeh - - 2014
Cell manipulation is instrumental in most biological applications. One of the most promising methods in handling cells and other biological particles is the magnetic manipulation technique. In this technique, magnetic nanoparticles are employed to magnetize cells. Such cells then can be manipulated, sorted, or separated by applying an external magnetic ...
Jin Xiulong X Shanghai Engineering Research Center of Medical Device and Technology at Med-X, School of Biomedical Engineering, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai, 200030, China. - - 2014
With the increasing need for multi-purpose analysis in the biomedical field, traditional single diagnosis methods cannot meet the requirements. Therefore new multifunctional technologies and materials for the integration of sample collection, sensing and imaging are in great demand. Core-shell nanoparticles offer a unique platform to combine multifunctions in a single ...
Lukas Vanessa A VA Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, - - 2014
To evaluate the sensitivity and specificity of classification of pathomimetically degraded bovine nasal cartilage at 3 Tesla and 37°C using univariate MRI measurements of both pure parameter values and intensities of parameter-weighted images. Pre- and posttrypsin degradation values of T1 , T2 , T2 *, magnetization transfer ratio (MTR), and ...
Gruner Christiane C Echocardiography Laboratory, University Hospital Zurich, Zurich, - - 2014
Echocardiographic quantification of mitral regurgitation (MR) can be challenging if the valve geometry is significantly altered. Our aim was to compare the quantification of MR by the recently developed real time three-dimensional (3D) volume color flow Doppler (RT-VCFD) method to the conventional two-dimensional (2D) echocardiographic methods during the MitraClip procedure. ...
Maritim Samuel S Department of Biomedical Engineering, Yale University, New Haven, CT, 06520, USA, - - 2014
Purposely designed magnetic resonance imaging (MRI) probes encapsulated in liposomes, which alter contrast by their paramagnetic effect on longitudinal (T1) and transverse (T2) relaxation times of tissue water, hold promise for molecular imaging. However, a challenge with liposomal MRI probes that are solely dependent on enhancement of water relaxation is ...
Xie Mei M University of Electronic Science and Technology of China, No. 2006, Xiyuan Ave, West Hi-Tech Zone, Chengdu, 611731, Sichuan, - - 2014
Markov random field (MRF) model is an effective method for brain tissue classification, which has been applied in MR image segmentation for decades. However, it falls short of the expected classification in MR images with intensity inhomogeneity for the bias field is not considered in the formulation. In this paper, ...
Ahlawat Shivani S The Russell H. Morgan Department of Radiology & Radiological Science, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD, 21287, USA, - - 2014
High-resolution multidetector computed tomography (MDCT) has played a pivotal role in assessing patients following trauma; however, recent advancements in technology including dual-energy CT, as well as multiplanar and three-dimensional (3D) capabilities, are expanding the potential clinical applications of CT to include nontraumatic pathologies. This article will review optimal technical parameters ...
Numano Tomokazu T Department of Radiological Science, Graduate School of Human Health Science, Tokyo Metropolitan University, 7-2-10, Higashiogu, Arakawa-ku, Tokyo, Japan; Human Technology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST). Electronic address: - - 2014
To demonstrate the feasibility of a novel MR Elastography (MRE) technique based on a conventional gradient-echo type multi-echo MR sequence which does not need additional bipolar magnetic field gradients (motion encoding gradient: MEG), yet is sensitive to vibration. In a gradient-echo type multi-echo MR sequence, several images are produced from ...
Briley-Saebo Karen K Department of Basic Science and Craniofacial Biology, New York University, New York, NY, - - 2014
Oxidation-specific epitopes (OSE) within developing atherosclerotic lesions are key antigens that drive innate and adaptive immune responses in atherosclerosis, leading to chronic inflammation. Oxidized phospholipids and malondialdehyde-lysine epitopes are well-characterized OSE present in human atherosclerotic lesions, particularly in pathologically defined vulnerable plaques. Using murine and human OSE-specific antibodies as targeting ...
Itatani Ryo R From the *Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University; and †Department of Radiology, Kumamoto Chuo Hospital, Tainoshima, Kumamoto, - - 2014
The objective of this study was to evaluate the clinical utility of 3-dimensional (3D) balanced turbo-field-echo (BTFE) magnetic resonance cholangiopancreatography (MRCP) with gate and track acquisition at 3 T. Using a 3-T unit, we subjected 52 consecutive patients to 3D BTFE MRCP with the navigator-gated technique and 3D turbo-spin-echo volume ...
Ley C J CJ Department of Clinical Sciences, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, - - 2014
Validated non-invasive detection methods for early osteoarthritis (OA) are required for OA prevention and early intervention treatment strategies. To evaluate radiography and low-field magnetic resonance imaging (MRI) for the detection of early stage OA osteochondral lesions in equine centrodistal joints using microscopy as the reference standard. Prospective imaging of live ...
Liu Jun - - 2014
Monoclinic Gd2O3:Eu3+ nanoparticles (NPs) possess favorable magnetic and optical properties for biomedical application. However, how to obtain its small enough NPs still remains a challenge. Here, we combined the standard solid state reaction with the laser ablation in liquids (LAL) technique to fabricate sub-10 nm monoclinic Gd2O3:Eu3+ NPs and explained ...
Dregely Isabel I Nuklearmedizinische Klinik, Klinikum rechts der Isar der Technischen Universität München, Munich, Germany, - - 2014
To implement and evaluate a dedicated receiver array coil for simultaneous positron emission tomography/magnetic resonance (PET/MR) imaging in breast cancer. A 16-channel receiver coil design was optimized for simultaneous PET/MR imaging. To assess MR performance, the signal-to-noise ratio, parallel imaging capability and image quality was evaluated in phantoms, volunteers and ...
Cheng Kai - - 2014
Development of multifunctional nanoparticle-based probes for dual T1- and T2- weighted magnetic resonance imaging (MRI) could allow us to image and diagnose the tumors or other abnormalities in an exceptionally accurate and reliable manner. In this study, by fusing distinct nanocrystals via solid-state interfaces, hybrid hetero-nanostructures were built to combine ...
Kim Hye Jin HJ From the Department of Radiology and Research Institute of Radiology (H.J.K., S.S.L., J.H.B., S.H.P., A.Y.K., H.K.H.) and Department of Surgery (J.C.K., C.S.Y.), University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-Gil, Songa-Gu, Seoul 138-736, - - 2014
Purpose To prospectively compare diagnostic performance of diffusion-weighted ( DW diffusion weighted ) imaging, gadoxetic acid-enhanced magnetic resonance (MR) imaging, both techniques combined (combined MR imaging), and computed tomography (CT) for detecting colorectal hepatic metastases and evaluate incremental value of MR for patients with potentially curable colorectal hepatic metastases detected ...
Zhao Huilin H From the Departments of Radiology (H.Z., X.L., Y.C., J.X.) and Neurosurgery (J. Wan), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 1630 Dongfang Road, Shanghai 200127, China; Philips Research North America, Briarliff Manor, NY (J. Wang); Department of Radiology, University of Washington, Seattle, Wash (J. Wang, D.S.H., C.Y.); and Biomedical Engineering & Center for Biomedical Imaging Research, School of Medicine, Tsinghua University, Beijing, China - - 2014
Purpose To assess fast three-dimensional ( 3D three-dimensional ) black-blood ( BB black blood ) magnetic resonance (MR) imaging as a noninvasive alternative to intraarterial digital subtraction angiography ( DSA digital subtraction angiography ) at quantifying moderate to severe carotid artery atherosclerotic disease. Materials and Methods Local ethics committee approval ...
Arthurs Owen J OJ Department of Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, Great Ormond Street, London, WC1N 3JH, UK, - - 2014
Just as there is a range of paediatric imaging techniques available during life, a similar repertoire is available as part of the foetal and perinatal postmortem examination. In this article, we review the literature regarding the diagnostic utility of postmortem radiography, US, CT and MRI in this clinical setting. There ...
Sterman Daniel H - - 2014
Introduction:Bronchoscopic Trans-Parenchymal Nodule Access (BTPNA) is a novel approach to accessing pulmonary nodules (PN). This real-time, image-guided approach was evaluated for safety, accuracy, and yield in the healthy canine model. Methods:A novel, inorganic model of sub-centimeter pulmonary nodules (PN) was developed, consisting of 0.25 cc aliquots of calcium hydroxylapatite (Radiesse) ...
Yuh Esther L EL ‡Brain and Spinal Cord Injury Center, San Francisco General Hospital and Trauma Center, San Francisco, California; §Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California; ¶Department of Neurosurgery, University of Utah, Salt Lake City, Utah; ‖Department of Neurosurgery, University of California, San Francisco, San Francisco, - - 2014
: Concussion is a significant public health problem that is receiving increased attention from physicians, the media, and the public. Recent studies suggest that persistent symptoms after concussion/mild traumatic brain injury (mTBI) may arise from structural or metabolic alterations in the brain, despite normal conventional neuroimaging studies. New, advanced neuroimaging ...
Wu Xin X 1 All authors: Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, NYU Langone Medical Center, 660 First Ave, 2nd Fl, New York, NY - - 2014
OBJECTIVE. Traditional fat-suppressed T1-weighted spin-echo or turbo spin-echo (TSE) sequences (T1-weighted images) may be degraded by motion and pulsation artifacts in head-and-neck studies. Our purpose is to evaluate the role of a fat-suppressed T1-weighted 3D radial gradient-recalled echo sequence (radial-volumetric interpolated breath-hold examination [VIBE]) in the head and neck as ...
Gou Shuiping S Xidian University, Xi'an, - - 2014
Objectives: MRI guided radiotherapy is particularly attractive for abdominal targets with low CT contrast. To fully utilize this modality for pancreas tracking, automated segmentation tools are needed. A hybrid gradient, region growth and shape constraint (hGReS) method to segment 2D upper abdominal dynamic MRI is developed for this purpose. Methods: ...
Siebelt M M Department of Orthopaedics, Orthopaedic Research Laboratory, Erasmus MC, The - - 2014
Hip osteoarthritis (OA) is characterized by cartilage degradation, subchondral bone sclerosis and osteophyte formation. Nowadays, OA is thought to develop via different etiologies that all lead to a similar form of end stage joint degradation. One of these subtypes is related to an abnormal shaped hip joint, like acetabular dysplasia ...
Guermazi A A Department of Radiology, Boston University School of Medicine, Boston, MA, USA. Electronic address: - - 2014
The aim of this review is to describe imaging techniques for evaluation of non-osteochondral structures such as the synovium, menisci in the knee, labrum in the hip, ligaments and muscles and to review the literature from recent clinical and epidemiological studies of OA. This is a non-systematic narrative review of ...
Zhang Zhijun Z School of Medicine, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, Oregon - - 2014
Rigid registration of intraoperative ultrasound (US) and preoperative CT image is important for providing real-time guidance during operations. However, due to the low spatial and temporal resolutions and the dissimilarity between US and CT, accurate registration of CT and US images is still a challenging problem. The authors propose an ...
Ozcan Umit Aksoy UA Department of Radiology, Acibadem University School of Medicine, Istanbul, Turkey. Electronic address: - - 2014
Background and purpose: In sedated pediatric brains, 2D-FLAIR causes increased signal intensity of the cerebrospinal fluid (CSF) leading to false-positive diagnoses. Our aim is to determine whether increased CSF signal intensity is observed on 3D-FLAIR images. Methods: In this institutional review board-approved study, a 2-year retrospective analysis of our MRI ...
Damato Antonio L AL Department of Radiation Oncology, Dana-Farber Cancer Institute/Brigham and Women's Hospital, Boston, Massachusetts - - 2014
To investigate the use of a system using electromagnetic tracking (EMT), post-processing and an error-detection algorithm for detecting errors and resolving uncertainties in high-dose-rate brachytherapy catheter digitization for treatment planning. EMT was used to localize 15 catheters inserted into a phantom using a stepwise acquisition technique. Five distinct acquisition experiments ...
Vogel Patrick - - 2014
While magnetic particle imaging (MPI) constitutes a novel biomedical imaging technique for tracking superpara magnetic nanoparticles in vivo, unlike magnetic resonance imaging (MRI), it cannot provide anatomical background information. Until now these two modalities have been performed in separate scanners and image co-registration has been hampered by the need to ...
Larson David B DB Department of Radiology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA, 94305-5105, USA, - - 2014
Modern CT is a powerful yet increasingly complex technology that continues to rapidly evolve; optimal clinical implementation as well as appropriate quality management and improvement in CT are challenging but attainable. This article outlines the organizational structure on which a CT quality management and improvement program can be built, followed ...
Cody Dianna D DD Department of Imaging Physics, University of Texas M.D. Anderson Cancer Center, 1400 Pressler Ave., Unit 1472, Houston, TX, 77030, USA, - - 2014
When determining a strategy for pediatric CT scanning, clinical staff can either elect to adjust routine adult-protocol parameter settings on a case-by-case basis or rely on pre-set pediatric protocol parameters. The advantages of the latter approach are the topic of this manuscript. This paper outlines specific options to consider, including ...
Shehata Monda L ML From the Department of Radiology, Mercy Catholic Medical Center, Darby, Pa (M.L.S., M.R.H., O.M.T.); Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass (T.A.B.); and Department of Radiology, Hannover Medical School, OE 8220, Carl-Neuberg-Str 1, 30625 Hannover, Germany (D.H., - - 2014
Coronary microcirculatory dysfunction has a fundamental role in the pathophysiology of ischemic coronary artery disease (CAD) as well as various other cardiovascular disorders. Invasive coronary angiography remains the standard of reference for diagnosis of CAD. Nevertheless, it has been well acknowledged that the degree of luminal narrowing of epicardial coronary ...
Salgado Rodrigo A RA From the Departments of Radiology (R.A.S., B.J.O.d.B., P.M.P.), Cardiology (B.S., P.L.V.H., C.V., J.B.), and Cardiothoracic Surgery (I.R.), Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem-Antwerp, Belgium; and Departments of Radiology (R.P.J.B., T.L.), Cardiothoracic Surgery (M.P.B.), and Cardiology (P.R.S.), University Medical Center Utrecht, Utrecht, the - - 2014
Transcatheter aortic valve replacement represents one of the most exciting medical technical developments in recent years, offering a much-needed therapeutic alternative for patients with severe aortic valve stenosis who, due to comorbidities and advanced age, are considered to be inoperable or at high surgical risk. The efficacy of this procedure ...
Rajiah Prabhakar P From the Cardiothoracic Imaging Section, Department of Radiology, University Hospitals Case Medical Center, Case Western Reserve University School of Medicine, 11100 Euclid Ave, Cleveland, OH 44106 (P.R.); and Cardiovascular Imaging Laboratory, Imaging Institute, Cleveland Clinic Foundation, Cleveland, Ohio - - 2014
Although 3-T magnetic resonance (MR) imaging is well established in neuroradiology and musculoskeletal imaging, it is in the nascent stages in cardiovascular imaging applications, and there is limited literature on this topic. The primary advantage of 3 T over 1.5 T is a higher signal-to-noise ratio (SNR), which can be ...
Huska Jonathan L JL Department of Clinical Studies (Huska, Gaitero, Brisson, Nykamp), Department of Biomedical Sciences (Thomason), Department of Population Medicine (Sears), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G - - 2014
Presence of residual material following mini-hemilaminectomy in dogs (n = 9) with spontaneous thoracolumbar intervertebral disc extrusion was prospectively investigated. Volume of extruded disc material within the vertebral canal and the proportion of residual material were determined using pre- and post-operative magnetic resonance imaging. The degree of spinal cord compression, ...
Li Jing-Sheng - - 2014
Using computed tomography (CT) or magnetic resonance (MR) images to construct 3D knee models has been widely used in biomedical engineering research. Statistical shape modeling (SSM) method is an alternative way to provide a fast, cost-efficient, and subject-specific knee modeling technique. This study aimed to evaluate the feasibility of using ...
Okumura Eiichiro E Department of Medical Radiological Technology, Kagoshima Medical Technology - - 2014
If patient information, such as identification number or patient name, has been entered incorrectly in a picture archiving and communication system (PACS) environment, the image may be stored in the wrong place. To prevent such cases of misfiling, we have developed an automated patient recognition system for chest CT images. ...
Ghariq Eidrees E C.J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, Zuid-Holland, The Netherlands. Electronic address: - - 2014
Dual-echo arterial spin labeling (DE-ASL) enables the simultaneous acquisition of BOLD and CBF fMRI data and is often used for calibrated BOLD and cerebrovascular CO2 reactivity measurements. DE-ASL, like all ASL techniques, suffers from a low intrinsic CBF SNR, which can be improved by suppressing the background signal via the ...
Steinseifer Isabell K IK Department of Radiology and Nuclear Medicine (766), Radboud University Medical Center, Nijmegen, The - - 2014
Volume selection in (1) H MR spectroscopic imaging (MRSI) of the prostate is commonly performed with low-bandwidth refocusing pulses. However, their large chemical shift displacement error (CSDE) causes lipid signal contamination in the spectral range of interest. Application of high-bandwidth adiabatic pulses is limited by radiofrequency (RF) power deposition. In ...
de Graaf Robin A RA Department of Diagnostic Radiology, Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, Connecticut, - - 2014
Carbon-13 ((13) C) magnetic resonance spectroscopy (MRS) has an intrinsically low NMR sensitivity that often leads to large acquisition volumes or long scan times. While the use of higher magnetic fields can overcome the sensitivity limitations, high radiofrequency (RF) power deposition associated with proton-decoupling limits the achievable gain. Two-dimensional (2D) ...
Chang Han Soo HS Department of Neurosurgery, Saitama Medical Center, Saitama Medical University, - - 2014
Study Design. Prospective Controlled TrialObjective. To describe a newly-found increased flow signal in phase-contrast magnetic resonance imaging observed in compressed segments of the spinal cord in patients with cervical spondylotic myelopathy (CSM)Summary of Background Data. Derangement of cerebrospinal fluid (CSF) movement in the spine is a well-known cause of syringomyelia. ...
Rangarajan Krithika K Krithika Rangarajan, Chandan J Das, Atin Kumar, Arun Kumar Gupta, Department of Radiodiagnosis, All India Institute of Medical Sciences, Ansari Nagar East, New Delhi 110029, - - 2014
Recognition and characterization of central nervous system infections poses a formidable challenge to the neuro-radiologist. Imaging plays a vital role, the lesions typically being relatively inaccessible to tisue sampling. The results of an accurate diagnosis are endlessly rewarding, given the availability of excellent pharmacological regimen. The availability of numerous magnetic ...
Hennedige Tiffany T Tiffany Hennedige, Gopinathan Anil, Department of Diagnostic Imaging, National University Health and Yong Loo Lin School of Medicine, Singapore 119074, - - 2014
Living donor liver transplant (LDLT) is a major surgical undertaking. Detailed pre-operative assessment of the vascular and biliary anatomy is crucial for safe and successful harvesting of the graft and transplantation. Computed tomography (CT) and magnetic resonance imaging (MRI) are currently the imaging modalities of choice in pre-operative evaluation. These ...
Saien Soudeh S Department of Computing Engineering, Bu-Ali Sina University, Hamedan, Iran. Electronic address: - - 2014
This work is focused on application of a new technique in the first steps of computer-aided detection (CAD) of lung nodules. The scheme includes segmenting the lung volume and detecting most of the nodules with a low number of false positive (FP) objects. The juxtapleural nodules were properly included and ...
Noda Yoshifumi Y Department of Radiology, Gifu University Hospital, 1-1 Yanagido, Gifu 501-1194, - - 2014
To quantitatively assess magnetic resonance (MR) imaging findings that help predict early post-therapeutic response in fibroids following uterine artery embolization (UAE). Fifteen patients with a total of 52 fibroids underwent UAE. The signal intensity ratio (SIR) on T1-, T2-, diffusion weighted and gadolinium-enhanced images were calculated by dividing the mean ...
Bayer Thomas T Department of Radiology, University of Erlangen-Nuremberg, Maximiliansplatz 1, 91054, Erlangen, Germany, - - 2014
The objectives of this study were the evaluation of flexor tendon pulley rupture of the fingers in the crimp grip position using magnetic resonance imaging (MRI) and the comparison of the results with MRI in the neutral position in a cadaver study. MRI in the crimp grip position and in ...
Swy Eric R ER Department of Radiology, Michigan State University, East Lansing, MI 48824, USA. - - 2014
Reports of molecular and cellular imaging using computed tomography (CT) are rapidly increasing. Many of these reports use gold nanoparticles. Bismuth has similar CT contrast properties to gold while being approximately 1000-fold less expensive. Herein we report the design, fabrication, characterization, and CT and fluorescence imaging properties of a novel, ...
Steele M A MA Nutreco Canada Agresearch, Guelph, Ontario, Canada N1G 4T2. Electronic address: - - 2014
Rumen development in calves has been evaluated by measuring papillae length, width, and density using microscopy for over 50 yr. Although common in the literature, disadvantages to this method exist, such as large variations in rumen papillae size and shape, small numbers of total papillae being measured, and the time ...
Klippel Stefan - - 2014
We demonstrate a concept for multi-channel MRI cell-labeling using encapsulated laser-polarized xenon. Two mammalian cell populations, each labeled with different synthetic xenon nanocarriers, either cryptophane-A cages or PFOB nanodroplets, are imaged by frequency selective saturation transfer (Hyper-CEST) resulting in a switchable 'two-color' xenon-MRI contrast. With fast and sensitive detection of ...
Caetano Rosângela R Institute of Social Medicine, State University of Rio de Janeiro (Universidade do Estado do Rio de Janeiro - UERJ), Rio de Janeiro, - - 2014
Background A meta-analysis aimed to evaluate the accuracy of positron emission tomography (PET) and PET-CT for detecting recurrence of differentiated thyroid carcinoma (DTC) not identified by (131) I whole body scintigraphy (WBS). Methods MEDLINE, EMBASE, LILACS and Cochrane databases were searched for studies published between January/1985 and March/2012. Systematic methods ...
1 2 3 4 5 6 7 8 9 10 >