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Qiu DA-Sheng DS Department of PET/CT, Hubei Cancer Hospital, Wuhan 430079, P.R. - - 2014
Metastatic tumours presenting as soft tissue metastasis (STM) are relatively rare. STM represents metastasis to the muscle and subcutaneous tissues. The majority of the currently available clinical or radiological data on STM consist of isolated case reports or reviews. The aim of this study was to report the manifestations, origin ...
Liu Lin L Dept. of Electrical & Computer Engineering, University of Florida, Gainesville, FL - - 2014
A fiber-optic 3D confocal scanning microendoscope employing MEMS scanners for both lateral and axial scan was designed and constructed. The MEMS 3D scan engine achieved a lateral scan range of over ± 26° with a 2D MEMS scanning micromirror and a depth scan of over 400 μm with a 1D ...
Liu Yiyan Y From the Nuclear Medicine Service, Department of Radiology, New Jersey Medical School, Rutgers University, Newark, - - 2014
A 53-year-old woman with bilateral proptosis and diffuse lymphadenopathy had FDG PET/CT for the evaluation of lymphoma. There were significant enlargements of the lacrimal glands, thickening of the intraorbital muscles, prominent parotid/submandibular glands, and FDG-avid lymphadenopathy in the neck, right axilla, and mediastinum. The findings were suggestive of either lymphoma ...
Eastman Joseph T JT Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, - - 2014
Cover illustration. Notothenioid fishes lack swim bladders, but species live temporarily or permanently in the water column. Without swim bladder, skeletal mass becomes a key determinant of buoyancy. In this issue of the Journal of Morphology, Joseph Eastman and coauthors (pp. 841-861 10.1002/jmor.20258) quantify the degree of skeletal ossification in ...
Mick Curtis G CG 1 All authors: Department of Radiology, University of Kansas Medical Center, 3901 Rainbow Blvd, Mail Stop 4032, Kansas City, KS - - 2014
OBJECTIVE. This literature review details the history, pharmacokinetics, and utility of (18)F-sodium fluoride (Na(18)F) PET/CT in detecting osseous metastases compared with the current standard of care, technetium-99m methylene diphosphonate ((99m)Tc-MDP) bone scintigraphy. Additional discussion highlights solutions to impediments for broader implementation of this modality and insight into the complementary roles ...
Göya Cemil C Departments of Radiology (C.G., C.H., S.H., M.G.Ç., M.T., A.B.) and Internal Medicine (M.S.D., M.K.), Medical School, Dicle University, Diyarbakır, - - 2014
To compare the diagnostic success rate of acoustic radiation force impulse (ARFI) elastography with those of sonography and computed tomography (CT) for acute pancreatitis at hospital admission. B-mode sonography and ARFI elastography were performed on 88 patients with symptoms of acute pancreatitis and 50 healthy control participants who were admitted ...
Yoshida Soichiro S Department of Urology, Tokyo Medical and Dental University Graduate School, Tokyo, - - 2014
Diffusion-weighted magnetic resonance imaging is a type of functional imaging that is increasingly being applied in the management of upper tract urothelial carcinoma and bladder cancer. The image contrast is derived from differences in the Brownian motion of water molecules in tissues. The homogenous high signal intensity of upper tract ...
Yoo Roh-Eul RE Department of Radiology, Seoul National University Hospital, 28 Yongon-Dong, Chongno-Gu, Seoul, Republic of - - 2014
Müllerian duct anomalies (MDAs) represent a wide spectrum of developmental abnormalities related to various gynecologic and obstetric complications, including primary amenorrhea, infertility, and endometriosis. The use of diverse imaging modalities, in conjunction with clinical information, provide important clues to the diagnosis of MDAs. Diagnostic imaging work-up for MDAs often begins ...
Ba Lei L Department of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Henan, PR China Department of Radiology, Taizhou Cancer Hospital, Zhejiang, PR - - 2014
Primitive neuroectodermal tumors (PNETs) constitute a rare type of malignant neuroectodermal tumors that have chromosomal translocations identical to Ewing's sarcoma (ES), and the characteristics of this disease remain unclear. To describe the clinical, radiological, and pathological features of peripheral PNETs (pPNETs) to enhance their recognition. The clinical, imaging, and pathologic ...
Pinney James R JR Bioengineering and Therapeutic Sciences, University of California, San Francisco , 1700 Fourth Street, Byers Hall Room 203, San Francisco, California 94158, United - - 2014
Adapting ways to functionalize polymer materials is becoming increasingly important to their implementation in translational biomedical sciences. By tuning the mechanical, chemical, and biological qualities of these materials, their applications can be broadened, opening the door for more advanced integration into modern medical techniques. Here, we report on a method ...
Boelmans Kai K Department of Psychiatry, Memory Clinic, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany, - - 2014
Increased deposition of α-synuclein in Parkinson's disease (PD) is known to be prominent in the brainstem and discussed to be clinically relevant for motor and non-motor features. Whether structural magnetic resonance imaging is capable to detect degraded tissue microstructure caused by increased deposition of α-synuclein at this predilection site in ...
Lezaic Luka L Department for Nuclear Medicine, University Medical Centre Ljubljana, Zaloska 7, 1525, Ljubljana, Slovenia, - - 2014
Primary hyperparathyroidism is a common endocrine disorder which is diagnosed biochemically and for which therapy is surgical. A prerequisite for minimally invasive surgery, which minimizes morbidity and cost, is accurate localization of the involved gland(s). The aim of this study was to evaluate the usefulness of (18)F-fluorocholine PET/CT for preoperative ...
Loch Ronald R Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO. Electronic address: - - 2014
Prostate cancer is among the most common causes of cancer and cancer deaths in men. Screening methods and optimal treatments have become controversial in recent years. Prostate magnetic resonance imaging (MRI) is gaining popularity as a tool to assist diagnosis, risk assessment, and staging. However, implementation into clinical practice can ...
Srisajjakul Sitthipong S Department of Radiology,Siriraj Hospital , Mahidol University, Bangkok, - - 2014
Placental adhesive disorder (PAD) is a serious pregnancy complication which occurs when the chorionic villi invade the myometrium. Placenta previa and prior cesarean section are the two important risk factors. PAD is classified on the basis of the depth of myometrial invasion( placenta accreta, placenta increta and placenta percreta). Magnetic ...
Hu Zhenhua - - 2014
Multimodality imaging of positron emission tomography/computed tomography (PET/CT) provides both the metabolic information and anatomic structure which is significantly superior to either PET or CT alone and has greatly improved its clinical applications. Due to the higher soft-tissue contrast of magnetic resonance imaging (MRI) and no extra ionizing radiation, PET/MRI ...
Marty G D GD Animal Health Centre, Ministry of Agriculture, Abbotsford, BC, - - 2014
Piscine reovirus (PRV) was common among wild and farmed salmonids in British Columbia, western Canada, from 1987 to 2013. Salmonid tissues tested for PRV by real-time rRT-PCR included sections from archived paraffin blocks from 1974 to 2008 (n = 363) and fresh-frozen hearts from 2013 (n = 916). The earliest PRV-positive sample was from ...
Eley Karen A KA Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK, - - 2014
To determine the potential of novel gradient echo parameters, "Black Bone" MRI as an alternative to CT in the identification of normal and prematurely fused cranial sutures both in 2D and 3D imaging. Thirteen children with a clinical diagnosis of craniosynostosis underwent "Black Bone" MRI in addition to routine cranial ...
van Niekerk Cornelis G CG Department of Pathology, Radboud University Medical Centre, P.O. Box 9101, 6500 HB, Nijmegen, The - - 2014
To correlate pharmacokinetic parameters of 3-T dynamic contrast-enhanced (DCE-)MRI with histopathologic microvascular and lymphatic parameters in organ-confined prostate cancer. In 18 patients with unilateral peripheral zone (pT2a) tumours who underwent DCE-MRI prior to radical prostatectomy (RP), the following pharmacokinetic parameters were assessed: permeability surface area volume transfer constant (K (trans)), ...
Alperin Noam N 1Department of Radiology, 2Department of Neurological Surgery, University of Miami, Miami, FL 3Department of Radiology, University of Munich, Munich, Germany 4Neurological Sursgery, University of Pittsburgh, PA, - - 2014
It has been well documented that along with tonsillar herniation, Chiari Malformation Type I (CMI) is associated with smaller posterior cranial fossa (PCF) and altered CSF flow and tissue motion in the cranio-cervical junction (CCJ). This study assesses the relationship between PCF volumetry and CSF and tissue dynamics toward a ...
Wang Yi Y Radiology, Weill Medical College of Cornell University, New York, New York, USA; Biomedical Engineering, Cornell University, Ithaca, New York, USA; Biomedical Engineering, Kyung Hee University, Seoul, South - - 2014
In MRI, the main magnetic field polarizes the electron cloud of a molecule, generating a chemical shift for observer protons within the molecule and a magnetic susceptibility inhomogeneity field for observer protons outside the molecule. The number of water protons surrounding a molecule for detecting its magnetic susceptibility is vastly ...
Naswa N N Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, - - 2014
Paragangliomas, or glomus tumors, are neoplasms arising from extra-adrenal chromaffin tissue. They frequently cause symptoms by over-production of catecholamines with known predilection to multicentricity. We describe the case of a patient with bilateral carotid body tumor who underwent a preoperative (68)Gallium labeled [1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid]-1-NaI3-Octreotide ((68)Ga-DOTANOC) positron emission tomography/computed tomography (PET/CT) ...
Pereira Hélder H 3B's Research Group - Biomaterials, Biodegradables and Biomimetics, Univ. Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, S. Cláudio de Barco, 4806-909 Taipas, Guimarães, Portugal; ICVS/3B's - PT Government Associated Laboratory, Portugal; Clínica Espregueira-Mendes F.C. Porto Stadium - FIFA Medical Centre of Excellence; Orthopedic Department Centro Hospitalar Póvoa de Varzim - Vila do Conde, Portugal. Electronic address: - - 2014
To overcome current limitations of Tissue Engineering strategies, deeper comprehension on meniscus biology is required. This study aims to combine biomechanical segmental analysis of fresh human meniscus tissues and its correlation with architectural and cellular characterization. Morphologically intact menisci, from 44 live donors were studied after division into three radial ...
Laifer-Narin Sherelle L SL Department of Radiology, New York Presbyterian Columbia University Medical Center, New York, NY. Electronic address: - - 2014
Postpartum and posttermination complications are common causes of morbidity and mortality in women of reproductive age. These complications can be broadly categorized into vascular, infectious, surgical, and neoplastic etiologies, or are due to ectopic implantation of placental or endometrial tissue. Causes of postpartum vascular complications include retained products of conception, ...
Jiang Xiaoyu X Department of Chemistry, Washington University, St. Louis, - - 2014
To quantify the effectiveness of SB415286, a specific inhibitor of GSK-3β, as a neuroprotectant against radiation-induced central nervous system (brain) necrosis in a mouse model. Cohorts of mice were treated with SB415286 or dimethyl sulfoxide (DMSO) prior to irradiation with a single 45-Gy fraction targeted to the left hemisphere (brain) ...
Chapiro Julius J From the Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology, The Johns Hopkins Hospital, Sheikh Zayed Tower, Suite 7203, 1800 Orleans St, Baltimore, MD 21287 (J.C., M.L., R.D., R.S., Z.W., V.T., L.J.S., I.R.K., J.F.G.); Department of Pathology, The Johns Hopkins Hospital, Baltimore, Md (L.D.W., T.C.); Philips Research, Medisys, Suresnes, France (D.L.); and Johns Hopkins Bloomberg School of Public Health, Baltimore, Md - - 2014
Purpose To evaluate the diagnostic performance of three-dimensional (3D) quantitative enhancement-based and diffusion-weighted volumetric magnetic resonance (MR) imaging assessment of hepatocellular carcinoma (HCC) lesions in determining the extent of pathologic tumor necrosis after transarterial chemoembolization (TACE). Materials and Methods This institutional review board-approved retrospective study included 17 patients with HCC ...
Ou Yangming Y Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, - - 2014
To evaluate DRAMMS, an attribute-based deformable registration algorithm, compared to other intensity-based algorithms, for longitudinal breast MRI registration, and to show its applicability in quantifying tumor changes over the course of neoadjuvant chemotherapy. Breast magnetic resonance images from 14 women undergoing neoadjuvant chemotherapy were analyzed. The accuracy of DRAMMS versus ...
Qi Xiaojun X Department of Radiology, Laboratory of Medical Imaging and Interventional Radiology, The First Hospital of China Medical University, 155 Nanjing Bei St, Shenyang, 110001, People's Republic of - - 2014
Hypericin (HYP) has been found avid to necrosis in small animal studies. We sought to evaluate the tissue distribution of (131)I-HYP in a large animal model and to explore the theranostic utilities of (131)I-HYP after radiofrequency ablation (RFA). This animal experiment was approved by the institutional ethics committee. Twenty-five male ...
Bluemke David A DA National Institutes of Health, Bethesda, MD - - 2014
Incidental findings are an important topic in diagnostic imaging. Because of the comprehensive nature of computed tomography (CT) scanning, incidental findings are found seemingly on almost every CT scan performed for a wide variety of reasons in a radiology department. Many of these incidental findings are benign and immediately dismissed, ...
Cole Lisa E LE Department of Aerospace and Mechanical Engineering, Bioengineering Graduate Program and ‡Harper Cancer Research Institute, University of Notre Dame , Notre Dame, Indiana 46556, United - - 2014
Microcalcifications are deposits of hydroxyapatite (HA) mineral within breast tissue and the most common abnormality detected by mammography when screening for breast cancer due to exhibiting greater X-ray attenuation than the surrounding tissue. However, the detection of microcalcifications is limited by the sensitivity and specificity of mammography. Therefore, the objective ...
Pachowsky Milena L ML High Field MR Centre, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria; Department of Trauma and Orthopaedic Surgery, University Hospital of Erlangen, Erlangen, - - 2014
The aim of this study was to determine in vivo high-resolution morphological and biochemical gender related differences in cartilage repair tissue (MACT). Forty patients were examined clinically and by MR scans at 3T-MRI (coronal 3D True-FISP sequence for morphologic assessment and multi-echo spin-echo T2-mapping for biochemical assessment of healthy cartilage ...
Kahkouee Shahram S Department of Radiology, National Research Institute of Tuberculosis and Lung Diseases, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Teherán, - - 2014
To evaluate the chest computed tomography (CT) findings of patients with isolated bronchial anthracofibrosis confirmed by bronchoscopy and histopathology. Fifty-eight patients with isolated bronchial anthracofibrosis (29 females; mean age, 70 years) were enrolled in this study. The diagnosis of bronchial anthracofibrosis was made based on both bronchoscopy and pathology findings ...
Nascimento Duarte D Serviço de Imagiologia do Serviço de Saúde da Região Autónoma da Madeira, Avenida Luís de Camões, nº 57, 9004-514, Funchal, Portugal, - - 2014
Bone tumours and tumour-like lesions are frequently encountered by radiologists. Although radiographs are the primary screening technique, magnetic resonance imaging (MRI) can help narrow the differential or make a specific diagnosis when a lesion is indeterminate or shows signs of aggressiveness. MRI can extend the diagnostic evaluation by demonstrating several ...
Christen Thomas T 1] Inserm, U836, Grenoble, France [2] Université Grenoble Alpes, Grenoble Institut des Neurosciences, Grenoble, - - 2014
A quantitative estimate of cerebral blood oxygen saturation is of critical importance in the investigation of cerebrovascular disease. While positron emission tomography can map in vivo the oxygen level in blood, it has limited availability and requires ionizing radiation. Magnetic resonance imaging (MRI) offers an alternative through the blood oxygen ...
Patriciu Alexandru A Electrical and Computer Engineering Department, McMaster University, 1280 Main St. West, Hamilton, ON, Canada. Electronic address: - - 2014
We present a breast tissue stabilization device that can be used in magnetic resonance imaging-guided biopsy. The device employs adjustable support plates with an optimized geometry to minimize the biopsy target displacement using smaller compression than the conventional parallel plates approach. It is expected that the reduced compression will cause ...
Mahvash Mehran M Department of Neurosurgery, Clinic of Köln-Merheim, University of Witten-Herdecke, Köln, Germany. Electronic address: - - 2014
Intracerebral hemorrhage (ICH) is the most significant complication of Deep Brain Stimulation (DBS). To prevent ICH, stereotactic contrast enhanced T1-weighted images are used to visualize vessels as source of hemorrhage. Susceptibility-Weighted Imaging (SWI) is an MRI sequence with improved visualization of susceptibility differences between tissues, particularly sensitive for brain veins. ...
Wiggenraad Ruud R Radiotherapy Centre West, Lijnbaan 32, 2501 CK, The Hague, The Netherlands, - - 2014
Stereotactic radiotherapy (SRT) of brain metastasis can lead to lesion growth caused by radiation toxicity. The pathophysiology of this so-called pseudo-progression is poorly understood. The purpose of this study was to evaluate the use of MRI cine-loops for describing the consecutive events in this radiation induced lesion growth. Ten patients ...
Bertolotto Michele M Department of Radiology, University of Trieste, Ospedale di Cattinara, Strada di Fiume 447, 34149, Trieste, - - 2014
Primary lymphoma of the spermatic cord is a rare disease accounting for about 1.6% of primary spermatic cord tumors. We hereby present a new case in which color Doppler ultrasound (US), contrast-enhanced US, and MRI suggested a specific diagnosis that was subsequently confirmed pathologically. Color Doppler US revealed mostly hypoechoic, ...
Oh Jong-Ryool JR From the *Department of Nuclear Medicine, Raphael Hospital; †Department of Nuclear Medicine, Kyungpook National University School of Medicine and Hospital; and ‡Department of Internal Medicine, Raphael Hospital, Daegu, Republic of - - 2014
Radioiodine is highly specific for detecting functioning thyroid tissue in the body. However, an unexpected radioiodine uptake can cause various false-positive results in whole-body scanning. We report a case of a 47-year-old woman who showed strong and focal uptake in the right pelvic area suggesting metastasis on the posttreatment whole-body ...
García-Talavera Paloma P From the Department of Nuclear Medicine, Hospital Clínico de Valladolid, Valladolid, - - 2014
A patient with primary hyperparathyroidism underwent radio-guided surgery by means of a γ-probe and a hand-held γ-camera. Before surgery, a parathyroid double-phase planar scintigraphy and an early SPECT/CT with Tc-MIBI were performed and suggested an ectopic parathyroid adenoma with early washout. The hand-held γ-camera was very useful for the localization ...
Salem Usama U From the *Department of Diagnostic Radiology, The University of Texas, MD Anderson Cancer Center, Houston, TX; †Department of Diagnostic Radiology, National Cancer Institute, Cairo University, Cairo, Egypt; and ‡Department of Hematopathology, The University of Texas, MD Anderson Cancer Center, Houston, - - 2014
A 70-year-old woman with squamous cell carcinoma of the lung and chronic lymphocytic leukemia/small lymphocytic lymphoma underwent PET/CT for initial staging. There was avid focal asymmetrical uptake at the left shoulder, concerning for metastasis. Magnetic resonance imaging performed for further evaluation showed an enhancing soft tissue process at the rotator ...
Lococo Filippo F From the *Unit of Thoracic Surgery, IRCCS-Arcispedale Santa Maria Nuova, Reggio Emilia, Italy; †Department of Nuclear Medicine, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland; ‡Department of Nuclear Medicine, IRCCS-Arcispedale Santa Maria Nuova, Reggio Emilia, Italy; and §Unit of Head and Neck Surgery, IRCCS-Arcispedale Santa Maria Nuova, Reggio Emilia, - - 2014
Herein we describe a rare case of neuroglial heterotopia (ectopic mature cerebral tissue) incidentally detected by F-FDG PET/CT. A 52-year-old female patient underwent F-FDG PET/CT for metabolic characterization of a left pulmonary nodule. F-FDG PET/CT revealed increased radiopharmaceutical uptake corresponding to the pulmonary nodule pathologically described as adenocarcinoma. Furthermore, an ...
Rahmathulla Gazanfar G The Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Department of Neurological Surgery, Neurological and Taussig Cancer Institutes, Cleveland Clinic, Cleveland, Ohio, - - 2014
Magnetic resonance imaging-guided laser interstitial thermal therapy (LITT) is a minimally invasive treatment modality with recent increasing use to ablate brain tumors. When originally introduced in the late 1980s, the inability to precisely monitor and control the thermal ablation limited the adoption of LITT in neuro-oncology. Popularized as a means ...
Khawaja Ranish Deedar Ali RD Division of Thoracic Radiology, MGH Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, USA. Electronic address: - - 2014
To assess lesion detection and diagnostic image quality of filtered back projection (FBP) reconstruction technique in ultra low-dose chest CT examinations. In this IRB-approved ongoing prospective clinical study, 116 CT-image-series at four different radiation-doses were performed for 29 patients (age, 57-87 years; F:M - 15:12; BMI 16-32kg/m(2)). All patients provided ...
Allen Brian C BC Abdominal Imaging, Department of Radiology, Wake Forest Baptist Medical Center, Wake Forest University School of Medicine, Medical Center Boulevard, 3rd Floor MRI, Winston-Salem, NC 27157-1088, USA. Electronic address: - - 2014
Magnetic resonance enterography (MRE) utilization has increased for the evaluation of small bowel diseases over the last several years. In addition to performing similarly to computed tomography enterography (CTE) in the evaluation of inflammatory bowel disease, MRE lacks ionizing radiation, can image the small bowel dynamically, and provides excellent soft ...
Roth Christopher G CG Department of Radiology, TJUH, Methodist, Thomas Jefferson University, 2301 South Broad Street, Philadelphia, PA 19148, USA. Electronic address: - - 2014
Magnetic resonance (MR) imaging surpasses all other imaging modalities in characterizing liver lesions by virtue of the exquisite tissue contrast, specificity for various tissue types, and extreme sensitivity to contrast enhancement. In addition to differentiating benign from malignant lesions, MR imaging generally discriminates between the various malignant liver lesions. Hepatocellular ...
Rinkinen Jacob J From the *Section of Plastic Surgery, Department of Surgery, and †Department of Biostatistics, University of Michigan; ‡Morphomics Analysis Group, Ann Arbor, MI; and §Department of Statistics and ∥Center for Statistical Science, Peking University, Beijing, - - 2014
Preoperative computed tomography (CT) evaluation of patients with nonsyndromic craniosynostosis (NSC) has focused on the bony cranial vault while ignoring the surrounding soft tissues. In this study, we posit that novel CT-derived temporal muscle and temporal fat pad morphomics (tissue thickness, area, and volume) can be used to calculate temporal ...
Gupta Kamini K Department of Radiodiagnosis, Dayanand Medical College and Hospital, Ludhiana, Punjab, - - 2014
Objective: The purpose of this study was to analyze the computed tomography (CT) features of fungal sinusitis and to correlate them with nasal endoscopy and histopathological findings. Materials and Methods: Our study included 16 patients of either sex and any age group who presented in the otorhinolaryngology clinic at our ...
Kauppinen Risto A RA School of Experimental Psychology and Clinical Research and Imaging Centre, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK. Electronic address: - - 2014
Ischaemia is a condition in which blood flow either drops to zero or proceeds at severely decreased levels that cannot supply sufficient oxidizable substrates to maintain energy metabolism in vivo. Brain, a highly oxidative organ, is particularly susceptible to ischaemia. Ischaemia leads to loss of consciousness in seconds and, if ...
Tsien Christina C Department of Radiation Oncology, University of Michigan Hospital and Health Systems, Ann Arbor, MI. Electronic address: - - 2014
In this article, we review the clinical applications of diffusion magnetic resonance imaging (MRI) in the radiotherapy treatment of several key clinical sites, including those of the central nervous system, the head and neck, the prostate, and the cervix. Diffusion-weighted MRI (DWI) is an imaging technique that is rapidly gaining ...
Matsuo Masayuki M Radiation Biology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, - - 2014
The tumor microenvironment is characterized by hypoxia, low pH, and high interstitial fluid pressure. Hypoxic regions in tumors with low partial pressure of oxygen (pO2) levels can result in resistance to radiotherapy, thus causing local failure. Therefore, it would be desirable to noninvasively measure pO2 levels in the tumor before, ...
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