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Brakenhoff Lkpm L Departments of Gastroenterology and Hepatology, Leiden University Medical Centre , The - - 2014
Objectives: To assess whether subclinical inflammatory changes are present on magnetic resonance imaging (MRI) in patients with inflammatory bowel disease (IBD) and arthralgia. Method: In this pilot study, painful hand joints [metacarpophalangeal (MCP), proximal interphalangeal (PIP), and/or distal interphalangeal (DIP)] of 11 IBD patients (age 18-45 years) with continuous pain ...
Ghadiri Mahtab M Brain and Mind Research Institute, University of Sydney, Sydney, New South Wales, - - 2014
A 42-year-old white man presented with cognitive impairment and behavioral changes followed by rapidly progressive motor and gait impairment. Magnetic resonance imaging revealed striking multifocal white matter signal change, areas of restricted diffusion, diffuse callosal signal change, and atrophy and hyperintensity of the corticospinal tracts. A broad range of etiologies ...
Boy Fatma Nur FN Department of Radiology, Fatih Sultan Mehmet Training and Research Hospital, E-5 Karayolu Uzeri, 34752 Atasehir, Istanbul, Turkey. Electronic address: - - 2014
To retrospectively evaluate the accuracy of multi-parametric magnetic resonance (MR) imaging including fat saturated (FS) T2-weighted, short-tau inversion recovery (STIR), diffusion-weighted (DW-MR), and dynamic-contrast-enhanced MR (DCE-MR) imaging techniques in the diagnosis of early inflammatory sacroiliitis and determine the additional value of DW-MR and DCE-MR images according to recently defined 'Assessment ...
Kim Boeun - - 2014
Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) are functional magnetic resonance (MR) imaging techniques that detect the water diffusion. DWI and ADC were applied to the intracranial lesions in two dogs with non-infectious inflammatory disease and brain tumor using low field magnet. Cavitated lesions showed hypointense center with hyperintense ...
Jolepalem Prashant P Department of Diagnostic Radiology and Molecular Imaging, Oakland University William Beaumont School of Medicine and Beaumont Health System, Royal Oak, Michigan; - - 2014
On (18)F-FDG PET, inflammatory processes can be one of the most confounding factors for interpretation, particularly when the presentation of the process is atypical, as it was in the case of sarcoidosis reported here. Clinicians should be aware that sarcoidosis may mimic lung malignancies and lymphomas, regardless of typical or ...
Wang Yu Y Jiangsu Key Laboratory of Molecular Imaging and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School of Southeast University, Nanjing, 210009, - - 2014
The inflammatory response in injured brain parenchyma after traumatic brain injury (TBI) is crucial in the pathological process. In order to follow microglia activation and neuroinflammation after TBI, we performed PET imaging in a rat model of TBI using (18)F-labeled DPA-714, a ligand of the 18-kDa translocator protein (TSPO). TBI ...
Wang Shi-Cun SC PET/CT Center, Anhui Provincial Hospital, Hefei, Anhui, - - 2014
Rheumatoid arthritis (RA) is a phenotypically heterogeneous, chronic, destructive inflammatory disease of the synovial joints. A number of imaging tools are currently available for evaluation of inflammatory conditions. By targeting the upgraded glucose uptake of infiltrating granulocytes and tissue macrophages, positron emission tomography/computed tomography with fluorine-18 fluorodeoxyglucose ((18) F-FDG PET/CT) ...
Jarraya Mohamed M Department of Radiology, Musculoskeletal Section, Boston University School of Medicine, Boston, MA, USA, - - 2014
Proliferative myositis (PM) along with proliferative fasciitis and nodular fasciitis are a group of pseudosarcomatous myofibroblastic proliferations. Although the histologic presentation of each is almost identical, the magnetic resonance imaging (MRI) appearance of proliferative myositis is closer to that of inflammatory myopathies. We report a case of PM in which ...
Leclerc-Jacob S S Department of Rheumatology, Henri Poincare University, Nancy Teaching Hospital, Nancy, - - 2014
Magnetic resonance imaging (MRI) colonography or enterography is increasingly used to assess disease activity and complications in inflammatory bowel disease (IBD). However, no study has evaluated the role of this imaging technique to assess sacroiliitis. The primary objective was to assess the prevalence of inflammatory sacroiliitis on MRI performed for ...
Shoda Hirofumi H Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo , Tokyo , - - 2014
Abstract A 75-year-old woman was admitted to our department because of backache and multiple joint pain. Serum C-reactive protein (CRP) level was 6.8 mg/dL, and serum rheumatoid factor and anti-citrullinated peptide antibody were negative. Magnetic resonance imaging (MRI) showed bone edema and synovitis of the sacroiliac joints. (18)Fluorodeoxyglucose-positron emission tomography ((18)FDG-PET) ...
Chan J M S JM Regional Vascular Unit, St Mary's Hospital, Imperial College Healthcare NHS Trust, Imperial College London, - - 2014
Identification of those patients with high-risk asymptomatic carotid plaques remains an elusive but essential step in stroke prevention. Inflammation is a key process in plaque destabilization and the propensity of atherosclerotic lesions to cause clinical sequelae. There is currently no clinical imaging technique available to assess the degree of inflammation ...
Leppert Ilana R IR Montreal Neurological Institute, 3801 University St, WB325, Montreal, QC, H3A 2B4, Canada, - - 2014
Gadolinium (Gd) enhancement of multiple sclerosis (MS) lesions on MRI scans is a commonly used outcome measure in therapeutic trials. However, enhancement depends on MRI acquisition parameters that might significantly alter detectability. We investigated how the difference in blood-brain barrier (BBB) permeability threshold between MRI protocols affects lesion detection and ...
Xiong Ying Y Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong Universitiy of Science and Technology, Wuhan, 430030, China, - - 2014
This study aimed to investigate inflammatory edema after cerebral ischemia through 7.0T MRI and proton magnetic resonance spectroscopy (MRS). All SD rats were randomly divided into sham operated group and middle cerebral artery occlusion (MCAO)-1 day, -3 day and -7 day groups. MRI scan of the brain was performed on ...
Young Benjamin D BD Department of Large Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, - - 2014
Magnetic resonance (MR) imaging characteristics are commonly used to help predict intracranial disease categories in dogs, however, few large studies have objectively evaluated these characteristics. The purpose of this retrospective study was to evaluate MR characteristics that have been used to differentiate neoplastic, inflammatory, and vascular intracranial diseases in a ...
Garcia-Ovejero Daniel D Hospital Nacional de Parapléjicos, SESCAM, Laboratorio de Neuroinflamación, Toledo, Spain ; - - 2014
Progesterone is an anti-inflammatory and promyelinating agent after spinal cord injury but its effectiveness on functional recovery is still controversial. In the current study, we tested the effects of chronic progesterone administration on tissue preservation and functional recovery in a clinically relevant model of spinal cord lesion (thoracic contusion). Using ...
Vandemoortele Thomas T Department of Thoracic Oncology, Pleural Diseases and Interventional Pulmonology, Hôpital Nord, Marseille, - - 2014
The FDG-PET (fluorine-18 fluorodeoxyglucose positron emission tomography) scan is used with increasing frequency to investigate pleural abnormalities and to determine the possibility of neoplastic invasion. However, false-positive findings are not uncommon and talc pleurodesis has been reported to cause hypermetabolic pleural thickenings up to 5 years after the procedure. We ...
Shibata Eisuke E Department of Radiology, Tokyo Metropolitan Police Hospital, 4-22-1 Nakano, Nakano-ku, Tokyo, 164-8541, Japan, - - 2014
To illustrate the CT findings of gastrointestinal anisakiasis. The Institutional Review Board approving this retrospective study waived the requirement for informed consent. Review of our emergency department's clinical records from September 2008 to January 2012 identified 41 consecutive patients who were diagnosed with gastrointestinal anisakiasis. 20 patients were diagnosed with ...
Vogel-Claussen Jens J MHH, Hannover, Germany ; - - 2014
Rationale: There is a need to develop novel non-invasive imaging biomarkers that help to evaluate anti-inflammatory asthma treatments. Objectives: To investigate whether the extent of the segmental lung edema measured noninvasively using TIRM MRI (Turbo-Inversion Recovery-Magnitude magnetic resonance imaging) corresponds to the severity of the regional allergic reaction determined by ...
Huang L-K LK Department of Radiology, Taipei Veterans General Hospital, Taipei, - - 2014
The risk of pulmonary tuberculosis (PTB) may increase with increased use of anti-tumour necrosis factor (TNF) treatment in inflammatory arthritis. To evaluate the impact of anti-TNF treatment on radiological manifestations of PTB. Between January 2007 and December 2012, the chest radiographs (CXRs) of 23 consecutive patients with newly diagnosed PTB ...
Ilic Vesna V Department of Nuclear Medicine, Lausanne University Hospital, Lausanne, - - 2014
Positron emission tomography (PET)/CT plays a major role in staging, assessing response to treatment and during follow-up of paediatric Hodgkin's lymphoma (HL). Owing to high sensitivity to detect viable tumoural tissue, negative PET/CT is highly predictive of survival. However, (18)F-FDG is not specific for malignant disease and may concentrate in ...
Aliaga Esther Sánchez ES Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: - - 2014
Diagnosis of multiple sclerosis (MS) is based on the demonstration of dissemination of lesions in space (DIS) and in time (DIT), as well as on the exclusion of an alternative neurologic disorder. As a paraclinical tool brain and/or spinal cord magnetic resonance imaging (MRI), showing typical lesion morphology, characteristic distribution ...
Skret-Magierło Joanna J Instytut Połoznictwa i Ratownictwa Medycznego, Uniwersytet Rzeszowski, Polska. - - 2014
Intracranial subdural hematoma is an exceptionally rare but life-threating complication of epidural and spinal anesthesia. The diagnosis is rather difficult because the initial symptoms mimic post-dural puncture headache. A 33-year-old primipara was admitted to the hospital at 38 weeks gestation for a cesarean section due to premature rupture of membranes ...
Seyam Raouf R Department of Urology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi - - 2014
A 32 year old lady presented with recurrent left flank pain for 4 weeks and chronic lower back pain. CT without contrast showed no stones and mild left hydronephrosis. CT of the spine suggested an inflammatory process at L5-S1 vertebra. The diagnosis was supported by a bone scan. Incidentally, the ...
Yan Zhongyu Z From the Department of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, - - 2013
Inflammatory myofibroblastic tumor (IMT) is chronic inflammatory lesions of unknown origins. The preoperative diagnosis for tumors in the sinonasal cavity is difficult to distinguish between IMT and aggressive malignancy in most cases. The purpose of this study was to evaluate the imaging features of IMT distinguishing the 2 types of ...
Wu Peilin - - 2013
Cancer is becoming the largest threat to human health. Apart from classical anti-cancer therapies such as surgery, chemotherapies, and radiotherapy, many new therapies are being developed or translated into clinical use. These therapies include various neoadjuvant chemotherapies, minimally invasive treatments, and molecular-targeted therapies. However, none of these methods benefit all ...
Poggenborg René Panduro RP Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Copenhagen University Hospital at Glostrup, Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, Division of Rheumatology, Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands, Optimus Clinical Research, University of New South Wales, Kogarah, NSW, Australia, Department of Rheumatology and Medicine, Copenhagen University Hospital at Gentofte, Department of Radiology, Copenhagen University Hospital at Herlev, Copenhagen, Denmark and Image Analysis Ltd, Leeds, - - 2013
Objective. In a comparative conventional MRI, dynamic contrast-enhanced (DCE)-MRI, CT and radiography study, the authors aimed to monitor whether inflammation is reduced or even eliminated and damage halted in PsA patients receiving anti-TNF therapy.Methods. A 48-week prospective open-label investigator-initiated trial of 41 biologic-naive patients treated with 40 mg adalimumab every ...
Gandjbakhch Frédérique F From the Department of Rheumatology, Pitie Salpetriere Hospital, APHP, Université Paris 6-UPMC, Paris, France; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK; Department of Rheumatology, Slagelse Hospital, Slagelse, Denmark; Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway; Hull York Medical School, University of York, York, UK; Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen, Denmark; and Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; St. George Hospital, University of NSW, Sydney, Australia; King Christian X's Hospital for Rheumatic Diseases, University of Southern Denmark, Odense, Denmark; and Department of Molecular Medicine and Pathology, Faculty of Medicine and Health Sciences, University of Auckland, Auckland, New - - 2013
To assess the predictive value of magnetic resonance imaging (MRI)-detected subclinical inflammation for subsequent radiographic progression in a longitudinal study of patients with rheumatoid arthritis (RA) in clinical remission or low disease activity (LDA), and to determine cutoffs for an MRI inflammatory activity acceptable state in RA in which radiographic ...
Gupta Rajesh R Department of Medicine, Akron General Medical Center, Akron, Ohio; - - 2013
Acute cerebellitis is an inflammatory process that usually affects bilateral cerebellar hemispheres in the pediatric population. Pseudotumoral hemicerebellitis is an extremely rare presentation in which unilateral cerebellar involvement mimics a tumor that can exert significant mass effect on the surrounding structures, which may require surgical intervention. Magnetic resonance imaging characteristics ...
Eisele Philipp - - 2013
In multiple sclerosis (MS) occasionally acute lesions show a reduced apparent diffusion coefficient (ADC) on magnetic resonance imaging (MRI); however, the underlying mechanism of this phenomenon is not known. We compared cerebrospinal fluid (CSF) findings with diffusion MRI signal characteristics of acute lesions in 25 patients with MS or a ...
Jaruszewski Kristen M KM Department of Pharmaceutics and Brain Barriers Research Center, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA; Molecular Neurobiology Laboratory, Department of Neurology, Neuroscience and Biochemistry/Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA; Department of Pharmaceutics, College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL 32307, - - 2014
Cerebral amyloid angiopathy (CAA) results from the accumulation of Aβ proteins primarily within the media and adventitia of small arteries and capillaries of the cortex and leptomeninges. CAA affects a majority of Alzheimer's disease (AD) patients and is associated with a rapid decline in cognitive reserve. Unfortunately, there is no ...
Do Bao Anh - - 2013
Inflammatory myofibroblastic tumor (IMT) is a borderline neoplasm with uncertain malignant potential. It is a rare disease also referred to as an inflammatory pseudotumor, a plasma cell granuloma, and an inflammatory fibrosarcoma. IMT rarely also involves the head and neck region with only 50 cases of laryngeal IMT reported in ...
Burns Natalie S - - 2013
OBJECTIVE. The orbit contains structures from which a wide spectrum of disease can arise. This article focuses on orbital anatomy and a simple compartmental approach to evaluating the orbit on diagnostic imaging. The characteristic findings of key fetal structural diseases and a wide spectrum of pediatric orbital disorders, including inflammatory ...
Panebianco Valeria - - 2013
Aim: To evaluate the efficacy of dynamic contrast-enhanced magnetic resonance (DCE-MR) in the response to anti-angiogenic-targeted agents in patients with metastatic renal cell cancer (mRCC). Twenty-eight consecutive patients with sub-diaphragmatic metastases from mRCC were included in the protocol after signed informed consent. Baseline characteristics were collected and patients were first ...
Cakmakci Emin E Department of Radiology, Sisli Etfal Training and Research Hospital, Istanbul, - - 2013
To compare the findings obtained by computerised tomography (CT) enterography, which uses oral neutral contrast material and non-contrasted diffusion-weighted magnetic resonance imaging (DW-MRI) technique and reveal the diagnostic value of DW-MRI in patients with inflammatory bowel diseases. Patients with established or clinically suspect diagnosis of inflammatory bowel disease were included ...
Shin Sung Ui - - 2013
To determine the different computed tomography (CT) findings of lymphedema, cellulitis, and generalized edema in the lower leg. CT images of 44 patients with confirmed lymphedema (n = 19), cellulitis (n = 11), or generalized edema (n = 14) were retrospectively reviewed. The following characteristics were evaluated: extent of edema, laterality, skin thickening, honeycombing, taller than ...
Uchino Rie R Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, - - 2014
Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis is diagnosed on the basis of pancreatic pain and hyperamylasemia. However, because the diagnosis of abdominal pain is not objective, there may be some cases of painless pancreatitis among patients with post-ERCP hyperamylasemia (PEH). We reviewed the computed tomography (CT) findings of PEH cases to ...
Paparo Francesco - - 2013
Inflammatory involvement of the spine and sacroiliac joints is the most peculiar feature of seronegative spondyloarthropathies (SpA), which include ankylosing spondylitis, psoriatic arthritis, reactive arthritis (Reiter's syndrome), enteropathic spondylitis (related to inflammatory bowel diseases) and undifferentiated spondyloarthropathies. SAPHO syndrome may also be considered a SpA, but there is no clear ...
Park Jun Young JY Division of Gastroenterology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
Inflammatory pseudotumor (IPT) of the liver is a rare disease characterized by chronic infiltration of inflammatory cells. However, the clinical characteristics and outcomes of IPT remain uncertain. Clinical features, image findings, and outcomes of 55 patients with histologically proven IPT were evaluated. They consisted of 26 men and 19 women ...
Dong Aisheng - - 2013
A 59-year-old man, who had a 3-year history of paroxysmal atrial fibrillation, was referred to our hospital because of palpitation for 12 hours. Atrial fibrillation was confirmed by ECG. F-FDG PET/CT scan was performed showing diffuse FDG uptake of the bilateral atrial walls. Enhanced chest CT showed that the bilateral ...
Muller-Felber Wolfgang - - 2013
Diagnostic approach and treatment of idiopathic inflammatory myopathies have changed considerably during the past decades. In this review, new insights in the pathogenesis, the role of muscle biopsy, and magnetic resonance imaging in the diagnostic process in children with suspected myositis are discussed. Current treatment strategies and complication management is ...
Wattjes Mike P - - 2013
Natalizumab is a monoclonal antibody against α4-integrin approved for the treatment of multiple sclerosis (MS) due to a positive effect on clinical and magnetic resonance imaging (MRI) outcome measures. However, one relatively rare but serious side effect of this drug is a higher risk of developing progressive multifocal leukoencephalopathy (PML). ...
Perlman Scott B - - 2013
PET/CT imaging has become an important part of the evaluation of patients with many types of cancer. This imaging modality can also be used to image areas of active inflammation, such as those occurring in patients with active inflammatory bowel disease (IBD) (Crohn's disease and ulcerative colitis). The standard methods ...
Sobic-Saranovic Dragana - - 2013
The objective of this review is to highlight the clinical utility of FDG-PET/CT for evaluation of patients with chronic sarcoidosis. The emphasis was on the potential advantages and disadvantages of this technique in these patients based on which recommendations were made. The advantage of FDG-PET/CT technique is that it can ...
Hammer Matthew R - - 2013
Noninvasive, nonionizing, multiparametric magnetic resonance (MR) imaging of the pelvis using a field strength of 3 T now provides a comprehensive assessment of perineal involvement in pediatric Crohn disease. MR imaging accurately evaluates inflammatory disease activity, and allows determination of the number and course of fistula tracts as well as their ...
Towbin Alexander J - - 2013
The term inflammatory bowel disease (IBD) is used to describe multiple idiopathic disorders of the gastrointestinal tract. As many as one-quarter of patients with IBD initially present in childhood or adolescence. Multiple methods can be used to diagnose IBD in this age group, including computed tomographic (CT) enterography, magnetic resonance ...
Hamans Bob - - 2013
BackgroundAnti-angiogenic treatment of glioblastoma characteristically results in therapy resistance and tumor progression via diffuse infiltration. Monitoring tumor progression in these patients is thwarted because therapy results in tumor invisibility in contrast-enhanced (CE) MRI. To address this problem, we examined whether tumor progression could be monitored by metabolic mapping using (1)H ...
Berzaczy Dominik - - 2013
We present a case of carotidynia that we believe supports its classification as a distinct inflammatory disease entity. Doppler sonography and cervical magnetic resonance imaging are appropriate imaging modalities for diagnosing presumed carotidynia.
Karam Adib R - - 2013
To describe the different patterns of gallbladder lumen opacification on gadoxetate disodium-enhanced liver magnetic resonance imaging (MRI). One hundred eighty-seven MRI examinations were reviewed by two abdominal imaging radiologists who described the different patterns of gallbladder opacification, based on comparing the post-contrast to the pre-contrast images. Four patterns of gallbladder ...
Vendhan Kanimozhi - - 2013
To describe and profile abnormalities of the lumbar spine in a cohort of patients with enthesitis related arthritis (ERA) as compared to a control group of adolescents with mechanical back pain. We performed a retrospective review of MRI lumbar spine scans of 79 patients (58 cases, 21 controls). The study ...
Koski Anniina Kaisa Elina - - 2013
Computed tomography (CT) is the most commonly used radiological response evaluation method in contemporary oncology. However, it may not be optimally suitable for assessment of oncolytic virus treatments due to paradoxical inflammatory tumor swellings, which result from virus treatments, particularly when viruses are armed with immunostimulatory molecules. Here we investigated ...
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