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Schievink Wouter I WI Department of Neurosurgery, Cedars-Sinai Medical Center, 127 South San Vicente Boulevard, Sixth Floor, A-6600, Los Angeles, CA, 90048, USA, - - 2014
Intracranial hypotension is known to occur as a result of spinal cerebrospinal fluid (CSF) leaking, which may be iatrogenic, traumatic, or spontaneous. Headache is usually, but not always, orthostatic. Spontaneous cases are recognized more readily than in previous decades as a result of a greater awareness of clinical presentations and typical ...
Vargas M I MI From the Divisions of Neuroradiology (M.I.V., I.B.-N., K.O.L.), Radiology (J.G., B.M.D.), and Neurology (R.S.), Geneva University Hospitals, Geneva, Switzerland; and Division of Radiology (J.-L.D.), Strasbourg University Hospitals, Strasbourg, France. - - 2014
Ischemia of the spinal cord is a rare entity with a poor prognosis. Brain ischemia is no longer a diagnostic challenge; on the contrary, ischemia of the spinal cord remains difficult, particularly in children. In this article, we illustrate the principal causes in children and adults, clinical presentation, different techniques ...
Bondoc Andrew B AB Imaging Program, Lawson Health Research Institute, London, Ontario, Canada; Department of Medical Biophysics, Western University, London, Ontario, - - 2014
The purpose of this study was to measure changes in cardiac function as cardiomyopathy progresses in a mouse model of Duchenne muscular dystrophy using 3-D ECG-gated echocardiography. This study is the first to correlate cardiac volumes acquired using 3-D echocardiography with those acquired using retrospectively gated micro-computed tomography (CT). Both ...
Ahmad Z Z University of Cambridge, - - 2014
Computed tomography (CT) of the spine has remained an important tool in the investigation of spinal pathology. This article helps to explain the basics of CT of the lumbar spine to allow the clinician better use of this diagnostic tool.
Ratnarajah Abarna A Acute Medicine, Frimley Park Hospital, Frimley, UK - - 2014
We describe the case of a young female presenting with myalgia, mildly raised creatine kinase and a rash. The discussion emphasises the importance of a systematic approach to muscle symptoms, the value of a detailed hand examination and the importance of magnetic resonance imaging in the investigation of muscular symptoms.
Vilchez Carlos C Department of Radiology, CEDIMAT, Plaza de la Salud, Santo Domingo, Dominican Republic, - - 2014
In tropical spastic paraparesis, spinal cord atrophy is a well-known finding in magnetic resonance imaging. But in contrast to histological reports, focal lesions of the spinal cord have only been described in imaging reports in exceptional acute cases. Here, we looked for such focal lesions and for alterations of diffusion ...
Renard Dimitri D Department of Neurology, CHU Nîmes, Hôpital Caremeau, Place du Pr Debré, 30029 Nîmes Cedex 4, France. Electronic address: - - 2014
The pathophysiological mechanism of white matter lesions (WML) and dilated Virchow-Robin spaces (DVRS), both frequently encountered in myotonic dystrophy 1 (DM1), is unclear. We studied the spatial co-existence of WML and DVRS in 6 DM1 patients with a 1.5T or 3T brain MRI. Co-localisation with DVRS was found in 86% ...
Sarawagi Radha R Associate Professor, Department of Radiodiagnosis, Mahatma Gandhi Medical College & Research Institute , Pillaiyarkuppam, Pondicherry, India - - 2014
We report three cases of Hirayama disease, cervical flexion myelopathy presenting as unilateral or bilateral asymmetric muscular atrophy of forearm and hand involving C7 - T1 myotomes in young males. MRI revealed asymmetric cord atrophy, altered signal intensity of cord, posterior dural detachment and enlarged posterior epidural space with multiple ...
Leyendecker Pierre P From the *Service de Biophysique et de Médecine Nucléaire, Hôpitaux Universitaires de Strasbourg, Strasbourg, France; †ICube, Université de Strasbourg/CNRS UMR 7357, Strasbourg, France; ‡Fédération de Médecine Translationnelle de Strasbourg (FMTS), Faculté de Médecine, Strasbourg, France; §Cabinet Radiologie Imagerie de Bischwiller, Bischwiller, France; and ¶Département de Radiothérapie, Centre Paul Strauss, Strasbourg, - - 2014
We report the results of whole body F-fluorocholine (FCH) PET/CT in a single patient with biochemical suspicion of prostate adenocarcinoma relapse and recent history of minor head injury. PET showed an intense area of increased FCH uptake in the right parietal bone, without any morphological abnormality on either CT or ...
Wilson James M - - 2014
The best method of identifying regions within pancreatic tumours that might benefit from an increased radiotherapy dose is not known. We investigated the utility of pre-treatment FDG-PET in predicting the spatial distribution of residual metabolic activity following chemoradiotherapy (CRT) in locally advanced pancreatic cancer (LAPC). 17 patients had FDG-PET/CT scans ...
Murphy Grainne G Joint Department of Medical Imaging, University Health Network, Mount Sinai Hospital and Women's College Hospital, University of Toronto, 610 University Ave., Toronto, ON M5G 2M9, - - 2014
Noncutaneous melanomas (NCM) are diverse and relatively uncommon. They often differ from cutaneous melanomas in their epidemiology, genetic profile and biological behavior. Despite the growing body of evidence regarding the utility of PET/CT in cutaneous melanoma, the data on its use in NCM is scarce. In this review we will ...
Issadore D D School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, PA 19104, - - 2014
Magnetic biosensors, based on nanomaterials and miniature electronics, have emerged as a powerful diagnostic platform. Benefiting from the inherently negligible magnetic background of biological objects, magnetic detection is highly selective even in complex biological media. The sensing thus requires minimal sample purification and yet achieves a high signal-to-background contrast. Moreover, ...
Riou Olivier - - 2014
To assess the feasibility and benefit of integrating four-dimensional (4D) Positron Emission Tomography (PET) - computed tomography (CT) for liver stereotactic body radiation therapy (SBRT) planning. 8 patients with 14 metastases were accrued in the study. They all underwent a non-gated PET and a 4D PET centered on the liver. ...
Barral M M Department of Abdominal Imaging, Hôpital Lariboisière, Assistance publique-Hôpitaux de Paris, 2, rue Ambroise-Paré, 75010 Paris, - - 2014
Acute colitis is often diagnosed on multidetector row computed tomography (MDCT) because patients with this condition present with abdominal pain and a variety of nonspecific symptoms. Acute colitis has multiple causes with varying degrees of severity. Analysis of the extent of colonic involvement, presence of specific MDCT imaging features and ...
Rauscher Isabel I German Cancer Consortium (DKTK), Heidelberg, - - 2014
PET/MR is a new multimodal imaging technique that is expected to improve diagnostic performance, especially in oncologic patients in certain indications. Apart from the clinical relevance of PET with (18)F-FDG, various other tracers exist and are increasingly used, which allow insights into multiple physiologic and biologic processes. In this review, ...
Diop A D AD Clermont-Ferrand University Hospital, Estaing University Hospital, Department of Radiology and Medical Imaging, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand cedex 1, - - 2014
Invasive peritoneal disease includes more than just peritoneal carcinomatosis. Although this is the most common aetiology, especially when a primary is found, other conditions may be responsible for peritoneal invasion. A rigorous analysis of CT features taken together with the clinical and biological context usually allows the main differential diagnoses, ...
Armao Diane D Department of Radiology and Department of Pathology and Laboratory Medicine, UNC Health Care System, Chapel Hill, NC, USA; Department of Physician Assistant Studies, Elon University, Elon, NC, USA. - - 2014
Concerns have increased about the potential health risks of ionizing radiation from computed tomography (CT) scans. This paper discusses the biological effects of radiation, describes research findings related to CT use, cites strategies for radiation dose reduction, and emphasizes the need to be judicious in ordering CT scans for children.
Hedgire Sandeep S SS Department of Abdominal Imaging and Intervention, Massachusetts General Hospital 55 Fruit St, Boston, 02114 MA, USA. Electronic address: - - 2014
The purpose of this study was to assess the attenuation characteristics of the Alloderm Biologic Mesh Spacer (ABMS) in the abdomen and pelvis. Of nine patients with ABMS, five underwent multidetector computed tomographic scans at 1, 4, and 7 months postsurgery. Two patients underwent positron emission tomography-computed tomography (PET-CT). The ...
Brioli Annamaria A Centre for Myeloma Research, Division of Molecular Pathology, The Institute of Cancer Research, London, - - 2014
The 14th International Myeloma Workshop Kyoto, Japan, 3-7 April 2013 The International Myeloma Workshop (IMW) is a biannual meeting that gathers experts in multiple myeloma (MM) from all over the world and scientists interested in clinical and biological aspects of myeloma. The 2013 IMW was held in Kyoto, Japan and ...
Li Junfeng J Department of Radiology, Heping Hospital Affiliated to Changzhi Medical College, No. 110, Yan'an Road (South), Changzhi City, Shanxi Province, China. Electronic address: - - 2014
Triple-negative breast cancer (TNBC), which characterized by distinct biological and clinical pathological features, has a worse prognosis because the lack of effective therapeutic targets. Breast MR is the most accurate imaging modality for diagnosis of breast cancer currently. MR imaging recognition could assist in diagnosis, pretreatment planning and prognosis evaluation ...
Saito Hideo H Department of Neurosurgery and Cyclotron Research Center, Iwate Medical University, Morioka, - - 2014
Lhermitte-Duclos disease is a rare disorder characterized by a slowly enlarging mass in the cerebellum. The exact nature of this lesion remains unclear, but it has been variously characterized as hypertrophy, hamartoma or benign neoplasm. Single-photon emission computed tomography (SPECT) with (123)I-iomazenil and (99m)Tc-ethyl cysteinate dimer (ECD) display central benzodiazepine ...
Lipfert Jan J Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of - - 2014
Single-molecule techniques make it possible to investigate the behavior of individual biological molecules in solution in real time. These techniques include so-called force spectroscopy approaches such as atomic force microscopy, optical tweezers, flow stretching, and magnetic tweezers. Amongst these approaches, magnetic tweezers have distinguished themselves by their ability to apply ...
Yeo Dong-Myung DM Department of Radiology, Seoul St. Mary's Hospital, Catholic University of Korea, Seoul, Republic of - - 2013
To investigate whether quantitative parameters derived from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) are correlated with angiogenesis and biologic aggressiveness of rectal cancer. A total of 46 patients with rectal cancer underwent DCE-MRI. Using a two-compartmental model, quantitative parameters (K(trans) , kep , ve , and iAUC) were calculated from ...
Stramare Roberto R Section of Radiology, Department of Medicine, University of Padua, Via Giustiniani 2, 35128, Padua, - - 2013
This study was done to propose a study protocol for patients with rheumatoid arthritis (RA) treated with biological agents, by evaluating the contribution of contrast-enhanced magnetic resonance (CE-MR) imaging, a software programme that calculates the volume of synovitis on CE-MR images, and contrast-enhanced ultrasound (CEUS). Sixteen patients with RA receiving ...
Maffione Anna Margherita - - 2013
FDG PET/CT has a recognized high predictive power to assess the response to neoadjuvant chemoradiation therapy (CRT) in patients affected by locally advanced rectal cancer (LARC), but a relatively high number of false-positive findings decrease its specificity: with the aim to solve this problem, a new method of imaging analysis ...
Doura Tomohiro - - 2013
We report a new strategy for designing a signal off-to-on-type (19)F MRI chemical probe that operates in biological environments. The present strategy is based on the control of adherence of a (19)F MRI chemical probe to certain blood proteins, accompanied by a change in transverse relaxation time of (19)F nuclei.
Naumann H D - - 2013
The effect of molecular weight of condensed tannins (CT) from a variety of warm-season perennial legumes commonly consumed by sheep and goats on anthelmintic activity has not been previously explored. The objectives of this study were to determine if molecular weight of CT from warm-season perennial legumes could predict the ...
Cao Binrui - - 2013
Magnetic nanoparticles (MNPs), which can be aligned along a magnetic field, were applied to generate large-scale assemblies of biological nanofibers with the orientation of the constituent nanofibers defined by the applied magnetic field. When decorated with MNPs, these nanofibers could be guided by the external magnetic field to become oriented ...
Gebhardt P - - 2013
Positron emission tomography/computer tomography (PET/CT) is an established method in preclinical research in small animal disease models and the clinical diagnosis of cancer. It combines functional information of the positron-emitting biomarker with the anatomical data obtained from the CT image. Thus, it allows for 4D in vivo investigation of biological ...
Romero-Aburto Rebeca - - 2013
Fluorinated graphene oxide (FGO) is reported for the first time as a magnetically responsive drug carrier that can serve both as a magnetic resonance imaging (MRI) and photoacoustic contrast agent, under preclinical settings, and as a type of photothermal therapy. Its hydrophilic nature facilitates biocompatibility. FGO as a broad wavelength ...
Ellingson Benjamin M - - 2013
To outline the pathogenesis of cervical spondylotic myelopathy (CSM), the correlative abnormalities observed on standard magnetic resonance imaging (MRI), the biological implications and current status of diffusion tensor imaging (DTI), and MR spectroscopy (MRS) as clinical tools, and future directions of MR technology in the management of CSM patients. A ...
Belloli Sara - - 2013
The prognosis of malignant gliomas remains largely unsatisfactory for the intrinsic characteristics of the pathology and for the delayed diagnosis. Multimodal imaging based on PET and MRI may assess the dynamics of disease onset and progression allowing the validation of preclinical models of glioblastoma multiforme (GBM). The aim of this ...
Leibfarth Sara - - 2013
Background. Combined positron emission tomography (PET)/magnetic resonance imaging (MRI) is highly promising for biologically individualized radiotherapy (RT). Hence, the purpose of this work was to develop an accurate and robust registration strategy to integrate combined PET/MR data into RT treatment planning. Material and methods. Eight patient datasets consisting of an ...
Niyazi Maximilian - - 2013
This study compared manually delineated gross tumour volume (GTV) and automatically generated biological tumour volume (BTV) based on fluoro-deoxy-glucose (FDG) positron emission tomography (PET)/CT to assess the robustness of predefined PET algorithms for radiotherapy (RT) planning in routine clinical practice. RT-planning data from 20 consecutive patients (lung- (40%), oesophageal- (25%), ...
Giurazza F - - 2013
Together with race, stature and age, sex is a main component of the biological identity. Thanks to its proportional correlation with parts of the human body, sex can be evaluated form the skeleton.
Liu Guocai - - 2013
To more accurately and precisely delineate a biologic target volume (BTV) for the positron emission tomography (PET)-guided radiotherapy treatment planning, we proposed a novel Hierarchical Mumford-Shah Vector Model (HMSMv), where the image-vector was composed of the molecular biological characteristics such as contrast, busyness and the standard uptake value (SUV) of ...
Sham E - - 2013
A range of nuclear magnetic resonance (NMR) techniques are employed to provide novel, non-invasive measurements of both the structure and transport properties of porous media following a biologically mediated calcite precipitation reaction. Both a model glass bead pack and a sandstone rock core were considered. Structure was probed using magnetic ...
Manfredi Riccardo - - 2013
To describe MR imaging features of non-hyperfunctioning neuroendocrine pancreatic tumours by comparing them to histopathology and to determine the accuracy of MR imaging in predicting biological behaviour. After institutional review board approval, we retrospectively reviewed 45 patients with pathologically proven NF-NET of the pancreas and ≥1 preoperative MR/MRCP examinations. Of ...
Chen Wengen - - 2013
A significant majority of atherosclerotic plaque ruptures occur in coronary arteries exhibiting none or only modest luminal narrowing on coronary angiography. Emerging data suggest the biological composition of an atherosclerotic plaque (vulnerability to rupture) rather than its degree of stenosis or size is the major determinants for acute clinical events. ...
Ramirez-Giraldo Juan C - - 2013
OBJECTIVE. The purpose of this study is to evaluate radiation dose reduction strategies in perfusion CT by using a biologic phantom. MATERIALS AND METHODS. A formalin-preserved porcine liver was submerged in a 32-cm-wide acrylic phantom filled with water. The portal vein was connected to a continuous flow pump. The phantom ...
Lee Jae-Hyun - - 2013
Various bio-medical applications of magnetic nanoparticles have been explored during the past few decades. As tools that hold great potential for advancing biological sciences, magnetic nanoparticles have been used as platform materials for enhanced magnetic resonance imaging (MRI) agents, biological separation and magnetic drug delivery systems, and magnetic hyperthermia treatment. ...
Leung Katherine - - 2013
Pheochromocytomas are relatively rare neuroendocrine tumors of the adrenal medulla. Their variable clinical presentation and biologic behavior often make accurate diagnosis challenging. A variable spectrum of imaging appearances--some of which may also mimic other diseases--has been recognized. This article reviews the epidemiology; associations; and clinical, biochemical, pathologic, and multimodality imaging ...
Wakefield Jennie C JC Cancer Research UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, DownsRd, Sutton, SM2 5PT, United - - 2013
Functional MR techniques report on a variety of biologic features of tumors: dynamic contrast-enhanced, diffusion-weighted, and intrinsic susceptibility-weighted MRI and MR spectroscopy reflect, at a simplistic level, vascularity, cellularity, hypoxic status, and metabolism, respectively. This article reviews the evidence for each of the functional MR readouts to determine these clinical ...
Psimadas Dimitrios - - 2013
Abstract The application of combined diagnosis and therapy through nanotechnology applications is attracting increasing attention worldwide. Polymeric self-assembled nanoparticles (NPs) have been studied for this purpose. Micelles and vesicles with or without a magnetic core can efficiently carry diagnostic and/or therapeutic agents to a desired target. The biological behavior of ...
Naswa Niraj - - 2013
Because of the increasing clinical importance of gastric carcinoids and the difficulty in diagnosing them, the need for non-invasive diagnostic methods is growing. Currently, the only reliable method is upper gastrointestinal endoscopy with biopsy. We report the case of a 32-year-old male where a combination of functional imaging studies ((18)F-fluorodeoxyglucose-positron ...
Phinikaridou Alkystis - - 2013
Despite advances in prevention, risk assessment and treatment, coronary artery disease (CAD) remains the leading cause of morbidity and mortality in Western countries. The lion's share is due to acute coronary syndromes (ACS), which are predominantly triggered by plaque rupture or erosion and subsequent coronary thrombosis. As the majority of ...
Shumei Ma - - 2012
Abstract Purpose: With the widespread use of computed tomography (CT), the risks of low-dose radiation from CT have been increasingly highlighted. This study aims to illustrate the CT -induced biological effects and analyze the potential beneficial or harmful outcomes so as to provide radiologists reasonable advice on CT usage. Materials ...
Mocharla Vani P - - 2012
CA II makes a good PET: Discovering positron emission tomography (PET) probes with high target affinities is challenging. PET probe discovery using in situ click chemistry uses (19) F-bearing fragments as (18) F surrogates. This ensures that the lead hits and PET probes have equivalent chemical or biological characteristics, making PET probe discovery ...
Pizzuti L M - - 2012
Imaging techniques, such as ultrasound imaging (US), computed tomography (CT), positron emission tomography-CT (PET-CT) or PET-magnetic resonance imaging (MRI), are highly accurate procedure in the lymph node enlargement detection, but none of them has the same sensitivity in the biological definition and in the cause of enlargement identification. Therefore, a ...
Adan Ana - - 2012
The interest in the systematic study of the circadian typology (CT) is relatively recent and has developed rapidly in the two last decades. All the existing data suggest that this individual difference affects our biological and psychological functioning, not only in health, but also in disease. In the present study, ...
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