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Situ Weijun - - 2014
Abstract Objective: Schizophrenia is a severe psychiatric illness. Although magnetic resonance imaging (MRI) has been widely used for detecting the brain structural and functional abnormalities in patients with schizophrenia, the findings are highly inconsistent between reports. This study is to investigate the structural changes in the brain of schizophrenic patients. ...
DeRosse Pamela P Center for Translational Psychiatry, The Feinstein Institute for Medical Research, Manhasset, NY; Division of Psychiatry Research, The Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, Glen Oaks, NY; - - 2014
Previous studies of nonclinical samples exhibiting schizotypal traits have provided support for the existence of a continuous distribution of psychotic symptoms in the general population. Few studies, however, have examined the neural correlates of psychometric schizotypy using structural and diffusion tensor imaging (DTI). Healthy volunteers between the ages of 18 ...
Kenk Miran M Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, - - 2014
Neuroinflammation and abnormal immune responses have been implicated in schizophrenia (SCZ). Past studies using positron emission tomography (PET) that examined neuroinflammation in patients with SCZ in vivo using the translocator protein 18kDa (TSPO) target were limited by the insensitivity of the first-generation imaging agent [(11)C]-PK11195, scanners used, and the small ...
Zhang Tianhao T Center for Biomedical Image Computing and Analytics, and Department of Radiology, University of Pennsylvania, Philadelphia, PA; These authors contributed equally to the article; - - 2014
Schizophrenia is a multifaceted mental disorder characterized by cognitive, perceptual, and affective symptom dimensions. This heterogeneity at the phenomenological level may be subserved by complex and heterogeneous patterns of structural abnormalities. Thus, delineating such patterns may improve the insight into the variability of disease and facilitate future magnetic resonance imaging-based ...
Salavati Bahar B Institute of Medical Science, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto, Ontario, - - 2014
Cognitive deficits are commonly observed in patients with schizophrenia. Converging lines of evidence suggest that these deficits are associated with impaired long-term potentiation (LTP). In our systematic review, this hypothesis is evaluated using neuroimaging literature focused on proton magnetic resonance spectroscopy, positron emission tomography, and single-photon emission computed tomography. The ...
Moran Marcel E ME National Institute of Mental Health, National Institutes of Health, Bethesda, - - 2014
Background: Diffusion tensor imaging is a neuroimaging method that quantifies white matter (WM) integrity and brain connectivity based on the diffusion of water in the brain. White matter has been hypothesized to be of great importance in the development of schizophrenia as part of the dysconnectivity model. Childhood-onset schizophrenia (COS), ...
Giedd Jay N JN Child Psychiatry Branch, NIMH, National Institutes of Mental Health, Bethesda, Maryland, - - 2014
The advent of magnetic resonance imaging, which safely allows in vivo quantification of anatomical and physiologic features of the brain, has revolutionized pediatric neuroscience. Longitudinal studies are useful for the characterization of developmental trajectories (i.e. changes in imaging measures by age). Developmental trajectories (as opposed to static measures) have proven ...
Rosa P G P PG Laboratory of Psychiatric Neuroimaging (LIM-21), Department and Institute of Psychiatry, Faculty of Medicine,University of São - - 2014
Background. Magnetic resonance imaging (MRI) studies have shown that brain abnormalities in psychosis might be progressive during the first years of illness. We sought to determine whether first-episode psychosis (FEP) subjects show progressive regional grey matter (GM) changes compared with controls, and whether those changes are associated with diagnosis, illness ...
Laurent Pierre-Eloi PE 1 Laboratoire d'Imagerie Interventionnelle Expérimentale, Aix-Marseille Université, 27 Blvd Jean Moulin, 13385 Marseille cedex 5, - - 2014
OBJECTIVE. The purpose of our study was to define the postmortem CT semiology of gas collections linked to putrefaction, postmortem "off-gassing," and decompression illness after fatal diving accidents and to establish postmortem CT diagnostic criteria to distinguish the different causes of death in diving. SUBJECTS AND METHODS. A 4-year prospective ...
Whipple E - - 2014
This study aims to compare neuroimaging measures of gray matter thickness and volume in the medial prefrontal and parietal areas of combat veterans with and without Post-Traumatic Stress Disorder (PTSD) and blast exposure. Secondary objectives include investigating the relationship between neuropsychological and imaging data. Twenty post-9/11 male combat veterans were ...
Tang Li-Rong LR Center of the Treatment in Depressive Disorders, Beijing Anding Hospital, Capital Medical University, Beijing 100088, China; Department of Radiology, Beijing Anding Hospital, Capital Medical University, Beijing 100088, - - 2014
Bipolar depression (BD) is a common psychiatric illness characterized by deficits in emotional and cognitive processing. Abnormalities in the subregions of the insula are common findings in neuroanatomical studies of patients with bipolar disorder. However, the specific relationships between morphometric changes in specific insular subregions and the pathogenesis of BD ...
Plitman Eric E Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, - - 2014
Findings from neuroimaging studies in patients with schizophrenia suggest widespread structural changes although the mechanisms through which these changes occur are currently unknown. Glutamatergic activity appears to be increased in the early phases of schizophrenia and may contribute to these structural alterations through an excitotoxic effect. The primary aim of ...
Jaiswal Manish - - 2014
We report the development of thermo-responsive magnetic hydrogels based on poly(N-isopropylacrylamide) encapsulation of Fe3O4 magnetic nanostructures (MNS). In particular, we examined the effects of hydrogels encapsulated with poly-ethylene glycol (PEG) and polyhedral oligomeric silsesquioxane (POSS) surface modified Fe3O4 MNS on magnetic resonance (MR) T2 (transverse spin relaxation) contrast enhancement and ...
Garg Vasant V Department of Radiology, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, OH, 44106, USA, - - 2014
To evaluate the feasibility and efficacy of CT-guided percutaneous administration and off-label use of Spot sterile carbon stain (GI Supply, Camp Hill, PA) to a single PET-positive mesenteric lymph node to allow identification during subsequent laparoscopic resection. An asymptomatic 61-year-old male veteran with past medical history only for benign prostatic ...
Meyerhoff Dieter J DJ Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA. Electronic address: - - 2014
This chapter critically reviews brain proton magnetic resonance spectroscopy ((1)H MRS) studies performed since 1994 in individuals with alcohol use disorders (AUD). We describe the neurochemicals that can be measured in vivo at the most common magnetic field strengths, summarize our knowledge about their general brain functions, and briefly explain ...
Chaim Tiffany M TM Laboratory of Psychiatric Neuroimaging, Department and Institute of Psychiatry, Faculty of Medicine, University of São Paulo, Sao Paulo, Sao Paulo, Brazil; Center for Interdisciplinary Research on Applied Neurosciences, University of São Paulo, Sao Paulo, São Paulo, Brazil; Program for Attention Deficit Hyperactivity Disorder, Department and Institute of Psychiatry, Faculty of Medicine, University of São Paulo, Sao Paulo, Sao Paulo, - - 2014
Attention-Deficit/Hiperactivity Disorder (ADHD) is a prevalent disorder, but its neuroanatomical circuitry is still relatively understudied, especially in the adult population. The few morphometric magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) studies available to date have found heterogeneous results. This may be at least partly attributable to some well-known ...
Zapałowicz K K dr med. Krzysztof Zapałowicz, Klinika Neurochirurgii i Chirurgii Nerwów Obwodowych, Uniwersytet Medyczny w Łodzi, Uniwersytecki Szpital Kliniczny im. WAM-CSW, ul. Żeromskiego 113, 90-549 Łódź, Polska, e-mail: - - 2013
The authors describe the use of bone cement containing calcium phosphate for vertebroplasty of the cavity in the base of odontoid process. A 23-year-old female patient was operated on by incision in lateral cervical area (anterior open access). After a blunt dissection, the working cannula (Kyphon) was introduced under fluoroscopic ...
Hu He - - 2013
The objective of this study was to evaluate the targeted T1-magnetic resonance imaging (MRI), quantitative biodistribution and toxicity of aptamer (AS411) conjugated Mn3O4@SiO2 core-shell nanoprobes (NPs) in human cervical carcinoma tumor-bearing mice. The NPs were firstly prepared by encapsulating a hydrophobic Mn3O4 core within an amino functionalized silica shell. The ...
Jing Zhang - - 2013
OBJECTIVE: This study aims to investigate the clinical performance of three-dimensional (3D) fast-recovery fast spin-echo (FRFSE) magnetic resonance dacryocystography (MRD) with topical administration of sterile saline solution for the assessment of the lacrimal drainage system (LDS). METHODS: A total of 13 healthy volunteers underwent both 3D-FRFSE MRD and two-dimensional (2D)-impulse ...
Yu Jiahui - - 2013
This research is aimed to develop a kind of poly(ethylene glycol) shell-sheddable magnetic nanomicelle as the carrier of doxorubicin (Dox) in order to enhance its cellular uptake ability, and achieve synchronous magnetic resonance imaging (MRI)-visible function. Firstly, the five-member rings in poly (l-succinimide) (PSI) were successively opened by the amino ...
Zaphiratos Valerie - - 2013
Sterile magnetic drapes are frequently used during surgery to hold metal instruments on the sterile field. Magnetic fields may potentially interfere with the function of cardiovascular implantable electronic devices such as pacemakers and implantable cardioverter defibrillators. In this study, we evaluated the potential magnetic interference of magnetic drapes on pacemaker ...
Muthiah Muthunarayanan - - 2013
The aim of this study is to prepare biocompatible and targetable nanoparticles in lymph nodes (LNs) for lymph node-specific magnetic resonance (MR) imaging. Mannan-coated superparamagnetic iron oxide nanoparticles (SPIONs) (mannan-SPION), carboxylic mannan-coated SPION (CM-SPION), and β-glucan-coated SPION (Glucan-SPION) have been developed to target antigen-presenting cells (APCs), for lymph node detection ...
Deli Martin - - 2012
PURPOSE: To assess the performance of sterile saline solution as the sole contrast agent for percutaneous magnetic resonance imaging (MRI)-guided epidural injections at 1.5 T. METHODS: A retrospective analysis of two different techniques of MRI-guided epidural injections was performed with either gadolinium-enhanced saline solution or sterile saline solution for documentation ...
Mi Peng - - 2012
Nanodevices for magnetic resonance imaging of cancer were self-assembled to core-shell micellar structures by metal complex formation of K(2)PtCl(6) with diethylenetriaminepentaacetic acid gadolinium (III) dihydrogen (Gd-DTPA), a T(1)-contrast agent, and poly(ethylene glycol)-b-poly{N-[N'-(2-aminoethyl)-2-aminoethyl]aspartamide} (PEG-b-PAsp(DET)) copolymer in aqueous solution. Gd-DTPA-loaded polymeric micelles (Gd-DTPA/m) showed a hydrodynamic diameter of 45 nm and a core ...
Dehvari Khalilalrahman - - 2012
Amyloid-β (Aβ) oligomers are more likely to be the pathogenic agents of Alzheimer's disease. Development of multiple approaches in detection and clearance pathway for Aβ, may eventually lead to diagnosis and treatments of AD. Following this concept, we proposed temperature-responsive magnetic drug delivery system (DDS). This system designed to enhance ...
Hammond Nancy A - - 2012
Contrast-enhanced multiphase CT and dynamic gadolinium-enhanced MR have been validated in the literature as outstanding modalities for the evaluation of pancreatic pathology. In addition to the more frequently seen pancreatic adenocarcinoma, neuroendocrine tumors of the pancreas and cystic lesions such as serous and mucinous cystadenomas and IPMNs, a variety of ...
Bhattacharya Anish - - 2012
ABSTRACT: Labeled leukocyte scintigraphy has been used as an indicator of pancreatic necrosis in patients with acute pancreatitis and proposed for the detection of infection in peripancreatic fluid collections. The authors present a PET/CT scan showing abnormal uptake of F-Fluorodeoxyglucose-labeled autologous leukocytes in a pancreatic pseudocyst, from which aspirated fluid ...
Iglesias-García J - - 2012
Differential diagnosis of solid pancreatic lesions remains as an important clinical challenge, mainly for the differentiation between mass forming chronic pancreatitis, autoimmune pancreatitis and pancreatic adenocarcinoma. Endoscopic ultrasound (EUS), computed tomography (CT) and magnetic resonance imaging (MRI) can all provide valuable and complementary information in this setting. Among them, EUS ...
Fukukura Yoshihiko - - 2012
To compare the apparent diffusion coefficients (ADCs) of pancreatic adenocarcinomas that appear hyperintense with clearly defined borders (clear hyperintense) with those that do not show clear hyperintense borders on diffusion-weighted magnetic resonance (MR) images. Institutional review board approval was obtained and informed consent was waived. Eighty patients with histologically confirmed ...
Tirkes Temel - - 2012
Pancreatic magnetic resonance (MR) imaging has become a useful tool in evaluating pancreatic disorders. Technical innovations in MR imaging have evolved over the last decade, with most sequences being performed in one or a few breath-holds. Three-dimensional sequences with thin, contiguous slices allow for improved spatial resolution on the postgadolinium ...
Fukukura Yoshihiko - - 2012
Purpose:To compare the apparent diffusion coefficients (ADCs) of pancreatic adenocarcinomas that appear hyperintense with clearly defined borders (clear hyperintense) with those that do not show clear hyperintense borders on diffusion-weighted magnetic resonance (MR) images.Materials and Methods:Institutional review board approval was obtained and informed consent was waived. Eighty patients with histologically ...
Bashir Mustafa R - - 2012
Multidetector-row CT (MDCT) imaging of the pancreas has important roles in diagnosis, staging, and treatment monitoring of a vast array of pancreatic diseases. Optimizing MDCT protocols not only requires an understanding of expected pathologies but also must take into account cumulative radiation dose considerations.
Arifin Dian R DR Russell H. Morgan Department of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, - - 2012
Microencapsulation is a commonly used technique for immunoprotection of engrafted therapeutic cells. We investigated a library of capsule formulations to determine the most optimal formulation for pancreatic beta islet cell transplantation, using barium as the gelating ion and clinical-grade protamine sulfate (PS) as a new cationic capsule cross-linker. Barium-gelated alginate/PS/alginate ...
Deprez F C - - 2012
We report the case of an 82-year-old female presenting with acute epigastric abdominal pain after traumatic blow on the epigastrum. High-resolution multimodal imaging comprising Ultrasound, CT and MR, correlation with laboratory blood analyses and a 6 months CT follow-up allowed us to make a definite diagnosis of traumatic heterotopic pancreatitis. ...
Moncayo Valeria M - - 2012
A 72-year-old woman with a history of diabetes mellitus presented with severe episodes of hypoglycemia, associated with diaphoresis and somnolence, for 1 year. Workup revealed high insulin and c-peptide. Given the clinical suspicion of an insulinoma, an MRI was performed, which demonstrated abnormal enhancement in the pancreatic head. An octreotide ...
Hur Bo Yun - - 2012
PURPOSE: To determine the characteristic magnetic resonance imaging (MRI) features of mass-forming autoimmune pancreatitis (AIP), which allow its differentiation from pancreatic adenocarcinoma (PAC). MATERIALS AND METHODS: MR images of 37 patients with either pathologically proven, mass-forming AIPs (n = 9) or PACs (n = 28) were retrospectively reviewed. The pancreatic ...
Kim J H - - 2012
Iron-containing fragmented islets or free iron released from dying cells could confound the interpretation of MRI of iron nanoparticle-labeled islets. Exclusion of small hypointense spots could be a useful strategy to avoid such artifact. We investigated whether this strategy could improve the estimation of functioning islet mass after islet transplantation. ...
Dinia Lavinia - - 2012
OBJECTIVE: To prospectively evaluate longitudinal changes in white matter lesions (WMLs) in migraineurs with aura, by magnetic resonance imaging (MRI), and to correlate WMLs modifications with patients' clinical characteristics. METHODS: Forty-one consecutive migraineurs with aura were followed for a mean time of 33.2 months. Patients underwent MRI at baseline and ...
Szabó Nikoletta - - 2012
Migraine is a common and disabling neurological disease. The pathomechanism that underlies the disorder is not entirely understood, and reliable biomarkers are missing. In the current analysis we looked for microstructural alterations of the brain white matter in migraine patients by means of diffusion-weighted magnetic resonance imaging. The measurements were ...
Tüzün Erdem - - 2012
Anti-N-methyl-D: -aspartate receptor (NMDAR) encephalitis has been recently identified as a fulminant encephalopathy, presenting with a variety of symptoms including behavioral change, amnesia and seizures suggesting cortical gray matter involvement. A 42-year-old woman presented with acute-onset clinical and magnetic resonance imaging (MRI) findings indicating brainstem and diencephalon involvement. Her neuropsychological ...
Asano Kenichiro - - 2012
Primary bone xanthoma is a rare type of tumor, and those developing primarily within the skull are even more unusual. In this case, a primary bone xanthoma of the clivus without endocrine or metabolic complications represents the first of this type to be reported. The patient, a 24-year-old woman, initially ...
Norikane Takashi - - 2012
A 53-year-old man who presented with mild headache and ophthalmodynia underwent carbon-11 methionine (MET) positron emission tomography (PET). MET PET images demonstrated intense uptake in the periphery of the brain, significantly higher than the physiological uptake in the brain. Biopsy specimens from the pachymeninx indicated hypertrophic pachymeningitis with IgG4-positive plasma ...
Kobayashi Shinjiro - - 2012
A 62-year-old man was admitted with dyspnea. Computed tomography (CT) revealed left massive pleural effusion and a cystic lesion in the posterior mediastinal compartment extending to the pancreatic head via the esophageal hiatus. The pleural effusion had a high amylase content. Based on these findings, we diagnosed mediastinal pancreatic pseudocyst ...
Shimizu Shuya - - 2012
Autoimmune pancreatitis (AIP) is characterized by irregular narrowing of the main pancreatic duct (MPD), and narrowing of the MPD is an essential criterion for the diagnosis of focal/segmental AIP according to the Japanese diagnostic criteria 2011. We report a 55-year-old man in whom magnetic resonance imaging showed two masses in ...
Gonoi Wataru - - 2012
Meandering main pancreatic duct (MMPD), which comprises loop type and reverse-Z type main pancreatic duct (MPD), has long been discussed its relation to pancreatitis. However, no previous study has investigated its clinical significance. We aimed to determine the non-biased prevalence and the effect of MMPD on idiopathic pancreatitis using non-invasive ...
Cagnin Annachiara A Department of Neurosciences, University of Padova, Via Giustiniani 5, Padua, Italy. - - 2012
The development of focal hand dystonia after a traumatic injury of the central or the peripheral nervous system is a rare condition with multifactorial predisposing factors. We report on a patient who developed focal dystonia of the left hand after a cervical whiplash injury. Magnetic resonance imaging did not show ...
Triantopoulou Charikleia - - 2012
Metastatic lesions of the pancreas are uncommon, accounting for approximately 2% of pancreatic malignancies. Many tumours involve the pancreas secondarily and may manifest with different clinical and imaging characteristics. Although many patients have widespread disease, isolated metastases can be found. Surgical management is associated with improved survival in these cases. ...
Tepper Stewart J - - 2011
Background.- Progression of migraine toward a more disabling chronic form of at least 15 days/month is linked with frequency of attacks. Magnetic resonance imaging (MRI) findings of iron accumulation in the brain, especially in periaqueductal gray and red nucleus, have been correlated with both duration of illness and frequency of ...
Segard Julien - - 2011
We conducted a retrospective study of 291 patients aged 75 years or older who were admitted to the emergency department and who underwent a computed tomography (CT) brain scan. Our aims were to assess the reasons for requesting an urgent CT brain scan, to record the diagnostic yield of cerebral ...
Chen Clark C - - 2011
BACKGROUND:: Entrapped temporal horn syndrome secondary to obstructive neoplastic lesions is most frequently treated by surgical excision of the offending lesion. Here we describe an alternate approach involving temporal horn to prepontine cistern shunting followed by radiosurgery of the offending lesion. METHODS: A 41-year-old woman with a history of meningomatosis ...
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