Search Results
Results 301 - 350 of 984
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Glenn Orit A - - 2009
MRI is being increasingly used to assess for fetal abnormalities. Although significant progress in the field of fetal MRI has occurred during the past 20 years, continued technical advances will likely contribute to significant growth of the field. Moreover, with continued hardware and software improvements, additional MRI sequences will likely ...
Wise L David - - 2009
BACKGROUND: This laboratory has been investigating the utility of X-ray micro-computed tomography (micro-CT) to produce high-resolution, 3D images of skeletal structures in common laboratory species. The present investigation uses micro-CT evaluation of skeletons from rabbit fetuses exposed to the known teratogen, hydroxyurea. METHODS: Groups of 4-6 mated Dutch Belted female ...
Lin Chien-Heng - - 2009
Cebocephaly is a very rare congenital midline facial anomaly characterized by a blind-ended single nostril and ocular hypotelorism, and is usually combined with alobar holoprosencephaly. We report here a case of alobar holoprosencephaly with cebocephaly and craniosynostosis. Chromosomal analysis revealed normal karyotyping. The facial dysmorphism was characterized by the single ...
Huibers Marieke - - 2009
We describe a case concerning alobar holoprosencephaly and proboscis diagnosed at 20+3 weeks gestation during routine sonographic scanning. The internal neural and craniofacial malformations of the fetus were confirmed using magnetic resonance imaging (MRI). Amniocentesis demonstrated trisomy 13 of a male fetus.
Wise L David - - 2009
BACKGROUND: Assessment of developmental toxicity has historically included assessment of fetal skeletal morphology after alizarin red staining. X-ray micro-computed tomography (micro-CT) produces high-resolution images of skeletal structures and was investigated as an alternative method. METHODS: Groups of 5 mated Crl:CD (SD) female rats each were administered vehicle or boric acid ...
Aslan Halil - - 2009
We describe the abnormal sonographic findings in the brain of a 26-week fetus, which increased the suspicion of isolated lissencephaly. Follow-up ultrasound examination and MRI depicted diffuse cortical agyria, microcephaly, hypotelorism, and proptosis. Cordocentesis showed a normal 46,XY karyotype, and no short arm deletion of chromosome 17 was detectable. Postmortem ...
Hankinson Todd C - - 2009
OBJECT: Pediatric neurosurgeons are increasingly called on to provide prognostic data regarding the antenatal diagnosis of ventriculomegaly. This study was designed to determine if there is a correlation between prenatal MR imaging results and the need for ventricular shunt placement during the neonatal period. METHODS: The authors retrospectively reviewed the ...
Linduska N - - 2009
INTRODUCTION: The purpose of this study was to evaluate whether currently available fetal Magnetic Resonance Imaging (MRI/MR) techniques are sufficient for the assessment of placental pathologies. We hypothesized that placental pathologies as detected and evaluated by MRI, would correlate with histological findings. PATIENTS AND METHODS: In a retrospective study, 45 ...
Koplay Mustafa - - 2009
Holoprosencephaly (HPE) and polycystic kidney disease (PKD) are genetically heterogeneous anomalies which can make up part of various syndromes or chromosomal anomalies. Due to the rapid lethality prognosis, early and precise prenatal diagnosis would be of great value. This case report describes extensive PKD involvement, already present in utero, in ...
Liu Feng - - 2010
Magnetic Resonance Imaging (MRI) is a promising tool for the noninvasive, longitudinal study of developing primate brains. We developed a protocol to scan pregnant baboons serially at 3T for up to 3h per session. This protocol includes procedures for animal preparation, anesthesia, MRI scanning, and post-scan animal care. We applied ...
Guibaud Laurent - - 2009
More than 20 years after its introduction, magnetic resonance imaging (MRI) is now considered a useful complementary tool in the imaging work-up of fetal brain structural anomalies, but its real contribution in neuro-fetal imaging is still controversial. Our purpose is to present an overview of the most valuable indications of ...
Pugash Denise - - 2009
Fetal magnetic resonance spectroscopy (MRS) is technically feasible in utero and demonstrates similar findings to those observed in neonatal populations. MRS can provide additional information to conventional T1- and T2-weighted imaging of the fetal brain. It is of particular use when subtle changes are present on conventional fetal MRI sequences, ...
Huang Hao - - 2009
The human brain is extraordinarily complex, and yet its origin is a simple tubular structure. Characterizing its anatomy at different stages of human fetal brain development not only aids in understanding this highly ordered process but also provides clues to detecting abnormalities caused by genetic or environmental factors. During the ...
Rutherford Mary A MA Medical Research Council Clinical Sciences Centre, Imperial College, Hammersmith Hospital, London, UK. - - 2009
Fetal magnetic resonance imaging (MRI) is a relatively new clinical application but is becoming increasingly used in fetal medicine in combination with the established technique of antenatal ultrasound. A review of the literature to date provides information for clinicians to help assess which patients they should be referring for fetal ...
Behairy Noha H - - 2010
OBJECTIVE: The objective of our study is to evaluate the contribution of adding MRI findings to sonographic data when assessing fetal anomalies and to determine how this addition may affect the management of pregnancy. STUDY DESIGN: We prospectively examined 26 fetuses who had sonographically suspected congenital anomalies over a period ...
Sawada Kazuhiko - - 2009
The aim of this study was to spatio-temporally clarify gross structural changes in the forebrain of cynomolgus monkey fetuses using 7-tesla magnetic resonance imaging (MRI). T(1)-weighted coronal, horizontal, and sagittal MR slices of fixed left cerebral hemispheres were obtained from one male fetus at embryonic days (EDs) 70-150. The timetable ...
Klein Olivier - - 2009
BACKGROUND: Cervical myelocystocele (CMC) is a very rare congenital malformation and belongs to the spectrum of skin-covered (occult) dysraphisms. Only 15 cases have been so far reported throughout the literature. We report the first case of CMC whose diagnosis was established prenatally by ultrasound imaging (US) followed by fetal magnetic ...
Wright C C Maternal and Fetal Health Research Centre, 1st Floor St Mary's Hospital, Hathersage Road, Manchester M13 0JH, UK. - - 2010
The role of magnetic resonance imaging (MRI) in fetal imaging is expanding. The depth of structural information provided by MRI means it is more than just a useful adjunct to ultrasound, as several structures are more clearly visualised and many of the limitations of ultrasound are avoided. Currently, MRI is ...
Tilea B - - 2009
To provide normal magnetic resonance imaging (MRI) reference biometric data of the fetal brain, to evaluate reproducibility and gender effect, to compare the two cerebral hemispheres and to compare MRI with ultrasonographic biometry, in a large cohort. Normal cerebral fetal MRI examinations were collected prospectively and several parameters were measured: ...
B Ganesh Rao - - 2009
MRI is a useful supplement to USG for the assessment of fetal brain malformations. Superior soft tissue contrast and the ability to depict sulcation and myelination are the strengths of MRI. Subtle or inconclusive USG abnormalities can be confirmed or ruled out by MRI. In some cases, additional findings detected ...
Dill P - - 2009
Fetal magnetic resonance imaging (MRI) is a well-established second line imaging modality in identifying complex pathologies of the central nervous system (CNS), especially when ultrasound (US) findings are equivocal. It may enable an early and precise diagnosis, which is essential in terms of management of pregnancy and pre-, peri- and ...
Sommerville R Brian - - 2009
Eosinophilic vasculitis has been described as part of the Churg-Strauss syndrome, but affects the central nervous system (CNS) in <10% of cases. A 39-year-old woman with a history of migraine without aura presented to an institution in an acute confusional state with concurrent headache and left-sided weakness. Laboratory evaluation showed ...
Ogbole Godwin - - 2009
Intracranial lipomas are rare benign neoplasms accounting for <0.1% of all primary brain tumours. Most lipomas were incidentally detected by autopsy or computed tomography (CT).These slow growing benign lesions are usually asymptomatic and rarely require surgery. We report the case of a 70-year-old Nigerian woman who presented with persistent headaches ...
Sergides I G - - 2009
Pituitary apoplexy is when there is acute haemorrhage into a pituitary adenoma. It presents with headache and altered consciousness with loss of pituitary function. Many cases have bitemporal hemianopia. Subarachnoid haemorrhage is in the differential diagnosis, but does not cause a similar visual field defect. Magnetic resonance imaging is required ...
Vaidhyanath Ram - - 2009
Severe acute headache is a common presenting symptom to an accident and emergency department. Spontaneous intracranial hypotension (SIH) is an increasingly recognised cause of these symptoms and has characteristic clinical and imaging findings. SIH is characterised by headache worse on standing, low opening cerebrospinal fluid pressures at lumbar puncture and ...
Otera Yuka - - 2009
INTRODUCTION: Proximal focal femoral deficiency (PFFD) is a rare skeletal disorder characterized by failure in development of the subtrochanteric region of the femoral shaft, with varying degrees of shortening of the proximal femur. OBJECTIVE: To investigate the potential of helical computed tomography as a prenatal diagnostic tool for bony abnormalities. ...
Astley Susan J - - 2009
Clinical and research advancements in the field of fetal alcohol spectrum disorders (FASD) require accurate and valid identification of FASD clinical subgroups. A comprehensive neuropsychological battery, coupled with magnetic resonance imaging, (MRI), MR spectroscopy (MRS), and functional MRI (fMRI) were administered to children with fetal alcohol spectrum disorders (FASD) to ...
Borrell Antoni - - 2009
First trimester sonographic markers are the only markers achieving detection rates above 50% in the prenatal detection of fetal aneuploidy. Although potentially they are the best markers, some concerns have arisen about its clinical application. Pitfalls may be due to inability to examine the markers, incorrect assessment, or incorrect interpretation ...
Benoist G - - 2008
OBJECTIVE: To evaluate the relative contributions to the diagnosis of fetal brain abnormalities of targeted ultrasound examination and magnetic resonance imaging (MRI) in fetuses infected with cytomegalovirus (CMV). METHODS: This was a retrospective analysis of targeted brain ultrasound examination and fetal brain MRI performed in fetuses diagnosed with CMV infection ...
Tutschek B - - 2008
Three-dimensional (3D) ultrasound volume acquisition, analysis and display of fetal structures have enhanced their visualization and greatly improved the general understanding of their anatomy and pathology. The dynamic display of volume data generally depends on proprietary software, usually supplied with the ultrasound system, and on the operator's ability to maneuver ...
Messing-Jünger A M AM Abteilung für Neurochirurgie, Asklepios Kinderklinik Sankt Augustin, Universität Bonn, Sankt Augustin, Germany. - - 2009
Specific conditions of the mother sometimes reduce the quality of ultrasound. In these cases, fetal magnetic resonance imaging (MRI) can be performed after gestational week (GW) 18. Interpretation of subtle disorders or malformations becomes safe not before GW 23. Clinical development of children with central nervous system (CNS) disorders is ...
Tang P H - - 2009
BACKGROUND AND PURPOSE: Anomalies associated with callosal agenesis (ACC) found postnatally have been well documented. However, to our knowledge, no detailed MR imaging analysis of associated anomalies has been reported in a large cohort of fetuses with ACC. This study will assess those anomalies and compare them with postnatal cohorts ...
Jani J - - 2008
OBJECTIVES: To investigate the potential value of antenatally determined total fetal lung volume (TFLV) by magnetic resonance imaging (MRI) in the prediction of the postnatal survival in congenital diaphragmatic hernia (CDH). METHODS: We examined fetuses with isolated CDH, in which MRI was used at 22-38 weeks of gestation to measure ...
Dicuonzo Franca - - 2008
Fetal stroke can occur between the 14th week of pregnancy and the beginning of labor. The incidence is approximately 17-35 of 100,000 live births. Risk factors are correlated to the mother, the pregnancy, or the factors associated with the fetus itself. Computerized tomography and magnetic resonance imaging are the most ...
Baughman W Christopher - - 2008
Placenta accreta (PA) encompasses various types of abnormal placentation in which chorionic villi attach directly to or invade the myometrium. PA is a significant cause of maternal morbidity and mortality and is now the most common reason for emergent postpartum hysterectomy. Its prevalence has risen tenfold in the United States ...
Pistorius Lourens R - - 2008
Much has been written recently about the relative merits and demerits of fetal imaging with ultrasound and magnetic resonance imaging (MRI). Unfortunately, the arguments often generate more heat than light. We attempted to identify the strengths and weaknesses of each modality from the literature, and to arrive at some practical ...
Saleem Sahar N - - 2008
OBJECTIVE: The purpose of this study was to evaluate the feasibility of imaging the fetal heart with a balanced steady-state free precession MRI sequence along the body and cardiac axes after inadequate echocardiography. SUBJECTS AND METHODS: After technically inadequate echocardiography, MRI was performed on 20 fetuses (mean gestational age, 24 ...
Jelin Angie C - - 2008
OBJECTIVE: This study was undertaken to evaluate intracranial magnetic resonance imaging abnormalities in the surviving fetus after a cotwin demise. STUDY DESIGN: This is a retrospective observational study evaluating the intracranial findings of surviving twins after demise of a monochorionic cotwin. A total of 47 cases of cotwin demise were ...
Cannie M - - 2008
OBJECTIVE: To quantify the degree of intrathoracic liver herniation by magnetic resonance imaging (MRI) and evaluate its effect on postnatal survival in fetuses with isolated congenital diaphragmatic hernia (CDH). METHODS: Forty fetuses that were expectantly managed and that were delivered after 32 weeks' gestation were included in this study. On ...
Bardo Dianna - - 2008
Magnetic resonance imaging (MRI) has become an important complementary imaging modality for evaluation of fetal and placental abnormalities over the past decade. MRI can function as a problem solver and help in patient counseling by confirming a suspected diagnosis, offering alternative diagnoses, and identifying additional abnormalities. This article addresses the ...
Hershkovitz R - - 2008
OBJECTIVE: To determine the incidence of prenatal isolated abnormal number of ribs, using three-dimensional (3D) ultrasound. METHODS: This was a prospective study of low-risk women with singleton pregnancy and normal fetal anatomy scan. 3D examinations of the fetal ribs were carried out at the time of the routine anomaly scan ...
Herman-Sucharska Izabela - - 2009
Sonography is the method of choice for prenatal malformation screening but it does not always provide sufficient information for correct diagnosis or adequate abnormality evaluation. Fetal magnetic resonance imaging (MRI) is considered as a valuable second line imaging tool for confirmation, completion and correction of sonographic findings. Fetal MRI has ...
Zhang Yanzhong - - 2008
The development of bioinspired or biomimetic materials is essential and has formed one of the most important paradigms in today's tissue engineering research. This paper reports a novel biomimetic nanocomposite nanofibers of hydroxyapatite/chitosan (HAp/CTS) prepared by combining an in situ co-precipitation synthesis approach with an electrospinning process. A model HAp/CTS ...
Mong Andrew - - 2008
BACKGROUND: Congenital high airway obstruction syndrome (CHAOS) is a rare disorder defined as any fetal abnormality that obstructs the larynx or trachea. Prompt airway intervention at delivery after accurate prenatal diagnosis may allow survival of this otherwise fatal condition. OBJECTIVE: To identify prenatal MRI findings in CHAOS, to compare these ...
Miyakoshi Kei - - 2008
Fetal scalp hemangioma in the occipital region is extremely rare and its accurate diagnosis is essential for perinatal management. We present a case of occipital scalp hemangioma diagnosed by prenatal sonography and magnetic resonance imaging (MRI). An echogenic mass measuring 29 mm x 23 mm x 30 mm was found ...
Picone Olivier - - 2008
OBJECTIVE: To evaluate whether fetal brain magnetic resonance imaging (MRI) adds useful information to the one obtained by ultrasound in fetuses with cytomegalovirus (CMV) infection. METHODS: MRI and ultrasonographic findings were analyzed retrospectively in 38 fetuses with proven congenital CMV infection. Both techniques were performed on the same week at ...
Hung Jeng-Hsiu - - 2008
A 28-year-old woman, gravida 1, para 0, was referred to our fetal diagnosis unit at 28(+2) gestational weeks because no fetal movements were detected. On 2-D ultrasonography, the cephalic axial view showed multiple hypoechoic spaces in the fetal brain, both cerebral cortex and occipital lobe showed bilateral defects, and the ...
Hatab Mustapha R - - 2008
OBJECTIVE: We sought to compare the fetal biometric values head and abdominal circumferences, biparietal and occipital-frontal diameters, and left and right ventricular atrial diameters obtained with contemporaneous sonography and 3D MRI reconstructions in term pregnancies. SUBJECTS AND METHODS: A total of 107 nulliparous women evaluated as having uncomplicated pregnancies and ...
Vázquez E - - 2008
Alexander disease (AD) is a rare neurodegenerative disorder characterized by megalencephaly, leukoencephalopathy, and Rosenthal fibers within astrocytes. This report describes the case of a female patient with sonography-detected ventriculomegaly at 32 weeks' gestation and distinctive MR imaging features at 33 and 36 weeks' gestation, at birth, and at 2 months ...
Manganaro L - - 2009
PURPOSE: To review our experience with fetal magnetic resonance imaging (MRI) to evaluate congenital heart disease (CHD). METHODS: We performed fetal MRI in 32 fetuses with an echocardiographically assessed CHD. Both direct and indirect signs of CHD were investigated. Direct signs considered were: morpho-volumetric abnormalities of the heart; malrotations; ventricular ...
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