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Muppa Radhika R Professor and Head, Department of Pedodontics, Panineeya Mahavidyalaya Institute of Dental Sciences and Research Centre, Hyderabad, Telangana, - - 2014
Endodontic therapy is successful only when thorough knowledge of root canal morphology is understood. Dens invaginatus is malformation of teeth resulting from invagination of tooth before biological mineralization occurs. It is clinically significant with an early pulpal involvement and chronic periapical lesion, which are often associated with this anomaly. The ...
Weis Joshua J JJ Division of General Surgery and Trauma, Department of Surgery, University of Pittsburgh, Pittsburgh, - - 2014
Many institutions now use empiric full-body computed tomography (CT) as a standard step in the initial workup of stable trauma patients. Recent data suggest that these scans may reveal unexpected injuries and improve survival in patients with polytrauma. However, patients who are unstable on presentation are often taken to the ...
Kucera Tomas T Department of Orthopaedic Surgery, Charles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Sokolska 581, 500 05, Hradec Kralove, Czech Republic, - - 2014
The purpose of the present study was to evaluate the role of diagnostic tools and management options for patients with pyogenic sacroiliitis, including potential complications. This retrospective study included 16 patients with pyogenic sacroiliitis who were admitted to a single orthopaedic centre between 2007 and 2012. The following data were ...
Black David F DF Radiology Department, Mayo Clinic, Rochester, - - 2014
Requests for after-hours emergent spine MR imaging seem to be increasing. We sought to review the trend in after hours spine MRI utilization at our institution and to determine how these results impacted therapeutic intervention. Following Institutional Review Board approval, reports from 179 after hours spinal MRI's performed over the ...
Baek Hye Jin HJ Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-Gil, Songpa-Gu, Seoul, 138-736, Republic of - - 2014
To determine the optimal clinical and CT findings for differentiating Kikuchi's disease (KD) and tuberculous lymphadenitis (TB) in patients presenting with cervical lymphadenopathy. From 2006 to 2010, 87 consecutive patients who were finally diagnosed with KD or TB were enrolled. Two radiologists performed independent analysis of contrast-enhanced neck CT images ...
Pandey Aditya S AS Department of Neurosurgery, University of Michigan, 1500 E. Medical Center Drive, Room 3552 TC, Ann Arbor, MI, 48109-5338, USA, - - 2014
Craniocervical arterial dissections (CCADs) represent a preventable cause of acute ischemic stroke (AIS). Our objective was to describe clinical presentation, imaging features, treatment strategies, and report clinical and imaging outcomes of CCADs at a large pediatric tertiary referral center. Electronic medical records were queried using variations of the word dissection ...
Seifen Tanja T Department of Nuclear Medicine and Endocrinology, Paracelsus Medical University Salzburg, Müllner Hauptstrasse 48, A-5020, Salzburg, - - 2014
We evaluated (18)F-fluoride PET/CT for the diagnosis of screw loosening after intervertebral fusion stabilization and compared the results with those from functional radiography. A group of 59 patients with pain in the region of previous intervertebral fusion stabilization and suspicion of implant instability due to screw loosening were investigated with ...
Wavreille Vincent V Department of Veterinary Clinical Sciences, Ohio State University, Columbus, - - 2014
To describe the magnetic resonance imaging (MRI), arthroscopic, and histopathologic changes in dogs with medial coronoid disease and to identify potential relationships between these findings. Retrospective case series. Twenty-five diseased medial coronoid processes (MCP) were collected from 19 dogs with a confirmed diagnosis of medial coronoid disease that were surgically ...
Kobayashi Naomi N Departments of aOrthopaedic Surgery bRadiology, Yokohama City University, Yokohama, - - 2014
The imaging diagnosis of osteoarthritis (OA) of the hip, especially in its early stages, is a technically challenging but essential aspect of our increased understanding of the pathophysiology of this disorder. We recently applied F-fluoride PET for the detection of abnormal bone turnover in early-stage OA. In our current study, ...
Lotfipour Ashley K AK From the *Ronald Reagan UCLA Medical Center, Los Angeles; †UCLA-Santa Monica Hospital, Santa Monica; and ‡Department of Health Policy & Management, UCLA Fielding School of Public Health; §Department of Biostatistics, UCLA School of Public Health; ∥Pfleger Liver Institute; and ¶Division of Digestive Diseases, UCLA Medical Center, Los Angeles, - - 2014
Under current guidelines, patients diagnosed with cirrhosis are to undergo initial and continued screening endoscopy for esophageal varices throughout the course of disease. Recent literature suggests that computed tomography (CT) of the abdomen is adequately sensitive for detecting grade 3 varices, those in need of immediate intervention. This study presents ...
Clayton Benjamin B Cardiology Department, Derriford Hospital, Plymouth, PL6 8DH, - - 2014
To assess the safety of our clinical practice using off-label intravenous metoprolol to facilitate computed tomographic (CT) coronary angiography METHODS: A retrospective analysis of scan reports and hospital admissions data was conducted to identify adverse events occurring following CT coronary angiography in patients who had received intravenous metoprolol prior to ...
Magalhães Rui R Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Porto, - - 2014
Background: The impact of public health interventions to reduce disability after stroke may be underestimated if only the modest effects on short-term disability are measured. We estimated the impact of differences in short-term functional outcome on long-term functional outcome. Methods: In a prospective community-based study from October 1998 to September ...
Haase Matthias M Division for Specific - - 2014
Context: Pharmacological inhibition of mineralocorticoid receptor (MR) signalling in patients with primary aldosteronism (PA) re-establishes aldosterone synthesis by non-diseased zona glomerulosa cells through activation of the renin-angiotensin-aldosterone-system (RAAS). In this context, current guidelines recommend discontinuing MR blockade for diagnostic procedures, including adrenal vein sampling (AVS). Discontinuation of MR blockade in ...
van Onna M M Department of Medicine, Division of Rheumatology, Maastricht University Medical Centre, and School for Public Health and Primary Care (CAPHRI), University of Maastricht , The - - 2014
Objectives: To describe the distribution and evolution over time of bone marrow oedema (BME) on magnetic resonance imaging of the sacroiliac joint (MRI-SIJ) in patients with recent-onset inflammatory back pain (IBP) suspected for axial spondyloarthritis (axSpA). Method: A 2-year follow-up study with annual MRI-SIJ was conducted in patients with IBP ...
Dammacco Franco F Guido Baccelli Unit, Department of Internal Medicine and Clinical Oncology, Policlinico, University of Bari Medical School, Piazza G. Cesare, n. 11, 70124, Bari, Italy, - - 2014
Conventional radiographic skeletal survey has been for many years the gold standard to detect the occurrence of osteolytic lesions in patients with multiple myeloma (MM). However, the introduction of more sensitive imaging procedures has resulted in an updated anatomic and functional Durie and Salmon "plus" staging system and has remarkably ...
Freesmeyer Martin M Clinic of Nuclear Medicine, Jena University Hospital, Bachstrasse. 18, 07740, Jena, Germany, - - 2014
Benign thyroid diseases are widely common in western societies. However, the volumetry of the thyroid gland, especially when enlarged or abnormally formed, proves to be a challenge in clinical routine. The aim of this study was to develop a simple and rapid threshold-based isocontour extraction method for thyroid volumetry from ...
Goudsmedt Françis F Department of General Surgery, AZ Sint Jan Brugge-Oostende, Ruddershove 10, Brugge, Belgium, - - 2014
Even though internal hernia (IH) after a laparoscopic Roux-en-Y gastric bypass (LRYGB) is a well-known entity for bariatric surgeons and radiologists, accurate diagnosis remains difficult. The aim of this study was to evaluate the sensitivity and specificity of ten different CT findings in patients with a proven internal hernia after ...
Nayak Anjali B AB Department of Pediatrics, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, 90095, USA, - - 2014
Exposure to gadolinium-based contrast agents (GBCA) in patients with chronic kidney disease (CKD) has been associated with the development of a potentially fatal disorder, nephrogenic systemic fibrosis (NSF). Although contrast-enhanced computed tomography (CT) is an alternative to magnetic resonance imaging (MRI), it carries the risk of radiation exposure and further ...
Taher Ali T AT American University of Beirut, Beirut, - - 2014
Liver iron concentration (LIC) assessment by magnetic resonance imaging (MRI) remains the gold standard to diagnose iron overload and guide iron chelation therapy in patients with non-transfusion-dependent thalassaemia (NTDT). However, limited access to MRI technology and expertise worldwide makes it practical to also use serum ferritin assessments. The THALASSA (assessment ...
Kottke Raimund R Department of Diagnostic Imaging, University Children's Hospital Zürich, - - 2014
Contrast-enhanced magnetic resonance imaging (MRI) is highly sensitive for assessing temporomandibular joint (TMJ) involvement in juvenile idiopathic arthritis (JIA), but only sparse data exist on normal TMJ appearance in children. To determine normal MRI appearance and enhancement pattern of pediatric TMJ as basis for diagnosing early arthritis. In 27 children ...
Rudmik Luke L Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Calgary, Calgary, Alberta, - - 2014
Idiopathic olfactory loss is a common clinical scenario encountered by otolaryngologists. While trying to allocate limited health care resources appropriately, the decision to obtain a magnetic resonance imaging (MRI) scan to investigate for a rare intracranial abnormality can be difficult. To evaluate the cost-effectiveness of ordering routine MRI in patients ...
Heidari Kamran K Department of Emergency Medicine, Loghman Hakim Hospital - - 2014
Abstract Primary objective: To identify if demographics, clinical and computed tomographic (CT) characteristics at first presentation and S100B concentrations at 3 and 6 hours after mild traumatic brain injury (MTBI) predict the development of post-concussion syndrome (PCS) after 1 month. Research design and methods: All consecutive MTBI patients (Glasgow Coma ...
Abdulrahman Yassir Y Trauma Surgery Section, Hamad General Hospital (HGH), P.O Box 3050, Doha, Qatar, - - 2014
The clinical significance of extended Focused Assessment with Sonography for Trauma (EFAST) for diagnosis of pneumothorax is not well defined. To investigate the utility of EFAST in blunt chest trauma (BCT) patients. A single blinded, prospective study. Participants: All patients admitted with BCT (2011-2013). Level 1 trauma center in Qatar. ...
Jaguszewski Milosz M Cardiology, University Heart Center, University Hospital Zurich, Switzerland, Raemistrasse 100, CH-8091, Zurich, - - 2014
Objectives: The aim of the study was to examine frequency, size and localization of peri-device leaks after percutaneous left atrial appendage(LAA)-closure with the AMPLATZER-Cardiac-Plug (ACP) by using a multimodal imaging approach, i.e. combined cardiac-CT and TEE follow-up. Background: Catheter-based LAA-occlusion using ACP aims to reduce the risk of stroke in ...
Martin Jon J Bradford Royal Infirmary, Bradford, - - 2014
PET with computed tomography (PET-CT) is an important imaging modality in the assessment of patients with cancer. The glucose analogue fluorine-18 2'-fluorodeoxyglucose (F-FDG) is a commonly used tracer in PET-CT. As we serve a diverse population with a high prevalence of diabetes mellitus (DM) and malignant disease, we wished to ...
van der Valk Fleur M FM Department of Vascular Medicine, Academic Medical Center, Amsterdam, the - - 2014
Understanding how leukocytes impact atherogenesis contributes critically to our concept of atherosclerosis development and the identification of potential therapeutic targets. The study evaluates an in vivo imaging approach to visualize peripheral blood mononuclear cell (PBMC) accumulation in atherosclerotic lesions of cardiovascular (CV) patients using hybrid single-photon emission computed tomography/computed tomography (SPECT/CT). ...
De Bonis Michele M From the Department of Cardiac Surgery, IRCCS San Raffaele Scientific Institute, Milan, Italy (M.D.B., E.L., G.L.C., N.B., F.P., M.C., T.N., O.A.); Department of Cardiac Surgery, University Hospital of Zurich, Zurich, Switzerland (F.M.); and Department of Cardiac Surgery, S. Croce Hospital, Cuneo, Italy (F.B.). - - 2014
To assess the long-term results of the edge-to-edge mitral repair performed without annuloplasty in degenerative mitral regurgitation (MR). From 1993 to 2002, 61 patients with degenerative MR were treated with an isolated edge-to-edge suture without any annuloplasty. Annuloplasty was omitted in 36 patients because of heavy annular calcification and in ...
Shin Na-Young NY Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, - - 2014
The aim of this study was to investigate whether pretreatment imaging modalities, including [18F]fluorodeoxyglucose positron emission tomography-computed tomography (PET-CT) and CT/magnetic resonance imaging (MRI) are helpful for the selection of patient groups requiring contralateral neck dissection in patients with hypopharyngeal squamous cell carcinoma (SCC). A total of 72 consecutive patients ...
Askar Mohamed H MH Department of Otolaryngology-Head and Neck Surgery, Tanta University, Tanta, - - 2014
This study aimed to evaluate the non-Food and Drug Administration-approved off-label use of a 10F Foley catheter as a tool during endoscopic frontal sinus surgery. A cohort of 40 patients with chronic frontal rhinosinusitis was prospectively evaluated using the Sino-Nasal Outcome Test (SNOT-22), computed tomography (CT) imaging, and endoscopic examination. ...
Gafter-Gvili Anat A Department of Medicine E, Institute of Hematology, Davidoff Cancer Center, Infectious Disease Unit, Associate Director, Chairman of the Research Authority, Department of Nuclear Medicine, Beilinson Hospital, Rabin Medical Center, Petah-Tikva, and the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Department of Medicine E, Institute of Hematology, Davidoff Cancer Center, Infectious Disease Unit, Associate Director, Chairman of the Research Authority, Department of Nuclear Medicine, Beilinson Hospital, Rabin Medical Center, Petah-Tikva, and the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Department of Medicine E, Institute of Hematology, Davidoff Cancer Center, Infectious Disease Unit, Associate Director, Chairman of the Research Authority, Department of Nuclear Medicine, Beilinson Hospital, Rabin Medical Center, Petah-Tikva, and the Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel. - - 2014
The diagnosis of patients with fever of unknown origin (FUO) remains a challenging medical problem. We aimed to assess the diagnostic contribution of FDG-PET/CT for the evaluation of FUO. We performed a 4-year retrospective single-center study of all hospitalized patients that underwent FDG-PET/CT for evaluation of FUO. The final diagnosis ...
Liu Ping P Department of Neurology & Brain Medical Center, the First Affiliated Hospital of Medical School of Zhejiang University, Hangzhou 310003, Zhejiang, - - 2014
Early and correct diagnosis of Parkinson's disease (PD) is critical for patient counseling and therapeutic management. The diagnostic accuracy of transcranial sonography of substantia nigra (SN-TCS) for early stage PD patients remains controversial. Dopamine transporter (DAT) imaging is sensitive to detect presynaptic dopamine neuronal dysfunction, and has been studied as ...
Postels Douglas G DG International Neurologic and Psychiatric Epidemiology Program, Michigan State University, East Lansing, Michigan; Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan; Department of Neurology, University of Rochester, Rochester, New York; Blantyre Malaria Project, University of Malawi College of Medicine, Blantyre, Malawi; College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan; Department of Radiology, Queen Elizabeth Central Hospital, Blantyre, Malawi; Department of Anatomy, University of St. Andrews, St. Andrews, Scotland; Department of Imaging Sciences, University of Rochester, Rochester, New York - - 2014
Our goals were to understand the brain magnetic resonance imaging (MRI) findings in children with retinopathy-negative cerebral malaria (CM) and investigate whether any findings on acute MRI were associated with adverse outcomes. We performed MRI scans on children admitted to the hospital in Blantyre, Malawi with clinically defined CM. Two ...
Lee Kwang-Hyun KH Department of Orthopedic Surgery, Hanyang University College of Medicine, Seoul, South - - 2014
To assess the incidence rate of carpal tunnel syndrome (CTS) in patients with rheumatoid arthritis (RA) and investigate the correlations between CTS and disease activity and duration in patients with RA. This retrospective cohort study was conducted to assess the incidence rate of CTS in 1070 patients with RA who ...
Gao P H PH Department of Radiology, Linyi People's Hospital, Shandong University, Linyi, Shandong, People's Republic of - - 2014
Isolated middle cerebral artery dissection (MCAD) is a rare but important clinical entity. The purpose of this study is to demonstrate the clinical and magnetic resonance imaging (MRI) features of symptomatic unruptured isolated MCAD. We retrospectively analyzed clinical characteristics and MRI features of eight consecutive ischemic stroke patients diagnosed with ...
Asada Shigeki S Department of Orthopaedic Surgery, Kinki University Faculty of Medicine, Japan. Electronic address: - - 2014
The patient-specific guide for total knee arthroplasty (TKA) is created from the data provided by magnetic resonance imaging (MRI) or computed tomography (CT) scans. It remains unknown which imaging technology is suitable for the patient-specific guide. The purpose of this study was to compare the accuracy of implant positioning and ...
Tauhid Shahamat S Department of Neurology, Brigham and Women's Hospital, Laboratory for Neuroimaging Research, Partners MS Center, Harvard Medical School, Boston, MA, - - 2014
While disease categories (i.e. clinical phenotypes) of multiple sclerosis (MS) are established, there remains MRI heterogeneity among patients within those definitions. MRI-defined lesions and atrophy show only moderate inter-correlations, suggesting that they represent partly different processes in MS. We assessed the ability of MRI-based categorization of cerebral lesions and atrophy ...
Pompe Esther E Department of Radiology and Internal Medicine-Geriatrics, University Medical Center Utrecht, Postbus 85500, Postbox: E.03.511, 3508, GA, Utrecht, Netherlands, - - 2014
The objective is to evaluate the effect of intravenous contrast media on bone mineral density (BMD) assessment by comparing unenhanced and contrast-enhanced computed tomography (CT) examinations performed for other indications. One hundred and fifty-two patients (99 without and 53 with malignant neoplasm) who underwent both unenhanced and two contrast-enhanced (arterial ...
Gatson Joshua W JW Departments of Surgery - - 2014
Object In previous studies of traumatic brain injury (TBI), neural biomarkers of injury correlate with injury severity and predict neurological outcome. The object of this paper was to characterize neurofilament-H (NFL-H) as a predictor of injury severity in patients who have suffered mild TBI (mTBI). Thus, the authors hypothesized that ...
Wei Hongxing H Department of Nuclear Medicine, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 10037, People's Republic of - - 2014
To compare the accuracy of end-diastolic and end-systolic volumes (EDV, ESV) and LV ejection fraction (LVEF) measured by both GSPECT and GPET, using cardiac magnetic resonance imaging (CMR) as a reference. Furthermore, the impacts of severe perfusion defects, akinetic/dyskinetic segments, and residual viable myocardium on the accuracy of LV functional ...
Aoyama Tatsuro T Department of Neurosurgery, Aichi Medical University, - - 2014
Object The object of this study was to evaluate the radiographic characteristics of C-2 using multiplanar CT measurements for anchor screw placement in patients with C-1 assimilation (C1A). Insertion of a C-2 pedicle screw in the setting of C1A is relatively difficult and technically demanding, and there has been no ...
Kiekara Tommi T Medical Imaging Centre, Tampere University Hospital, Finland. Electronic address: - - 2014
This study aimed to evaluate the association between magnetic resonance imaging (MRI) findings of tunnel communication and increased graft signal intensity (SI) and clinical evaluation of knee stability and outcome after double-bundle (DB) anterior cruciate ligament (ACL) reconstruction. Fifty-nine patients were evaluated with 1.5 T MRI and with clinical evaluation 2 years ...
Fuster David D Nuclear Medicine Department, Hospital Clinic, Villarroel 170, 08036, Barcelona, Spain, - - 2014
To prospectively compare (18)F-FDG PET/CT and MRI in the diagnosis of haematogenous spondylodiscitis METHODS: The study included 26 patients (12 women, 14 men; mean age 59 ± 17 years) with clinical symptoms of infection of the spine. Patients who had had prior spinal surgery or any type of antibiotic therapy in the previous ...
Legrand L L From the Departments of Radiology (L.L., M.T., O.N., M.E., C.M., J.-F.M., C.O.) and Neurology (G.T., J.-L.M, J.-C.B.), Université Paris Descartes Sorbonne Paris Cité, Centre de Psychiatrie et Neurosciences, Institut National de la Santé et de la Recherche Médicale S894, Centre Hospitalier Sainte-Anne, Paris, - - 2014
In acute stroke with proximal artery occlusion, FLAIR vascular hyperintensities observed beyond the boundaries of the cortical lesion on DWI (newly defined "FLAIR vascular hyperintensity-DWI mismatch") may be a marker of tissue at risk of infarction. Our aim was to compare the occurrence of FLAIR vascular hyperintensity-DWI mismatch relative to ...
Germans Menno R MR Deparment of Neurosurgery, Neurosurgical Center Amsterdam, Academic Medical Center (AMC), H2-241 Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands, - - 2014
In 15 % of all spontaneous subarachnoid hemorrhages (SAH), no intracranial vascular pathology is found. Those non-aneurysmal hemorrhages are categorized into perimesencephalic SAH (PMSAH) and non-perimesencephalic SAH (NPSAH). Searching for spinal pathology might reveal a cause for the hemorrhage in some patients. Our goal was to assess the yield of magnetic ...
Focardi Marta M Department of Cardiovascular Diseases, University of Siena, Viale Bracci 1, Policlinico 'Le Scotte', Siena 53100, - - 2014
Right ventricle fractional area change (RVFAC), tissue Doppler and M-mode measurements of tricuspid systolic motion [tricuspid Sm and tricuspid annular plane systolic excursion (TAPSE)], and 3D echocardiography are the current non-invasive methods for the quantification of RV systolic function; RV deformation analysis by speckle-tracking echocardiography (STE) has recently allowed the ...
Kim Eu Hyun EH Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222, Banpo-daero, Seocho-gu, Seoul, 137-701, Republic of - - 2014
To evaluate imaging findings of hepatic epithelioid hemangioendothelioma (HEH), with emphasis on solitary form at the initial presentation. Ten cases of pathologically confirmed HEH were retrospectively reviewed; seven patients had CT and MR images and three had only CT images. Two radiologists assessed the followings in consensus: lesion number, size, location, ...
Jiang Libing - - 2014
IntroductionThe purpose of this meta-analysis was to explore the value of whole-body computed tomography (WBCT) in major trauma patients (MTPs).MethodsA comprehensive search for articles from Jan 1, 1980 to Dec 31, 2013 was conducted through PubMed, Cochrane Library database, China biology medical literature database, Web of knowledge, ProQuest, EBSCO, OvidSP, ...
Garros Aurélien A Department of Hepato-Gastroenterology, University Hospital of Rennes, Pontchaillou, - - 2014
Assessment of perianal Crohn's disease remains challenging. European Crohn's and Colitis Organisation (ECCO) recommend magnetic resonance imaging (MRI) as a gold standard, but both accuracy and advantages remain limited compared to systematic clinical assessment. The aim of this study was to define their actual diagnostic value. We performed a retrospective ...
Jiang Xin-Hua XH Department of Radiology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong 510060, PR - - 2014
To characterize the computed tomography (CT) and magnetic resonance imaging (MRI) findings of Castleman disease of the neck. The imaging findings of 21 patients with Castleman disease of the neck were reviewed retrospectively. Of the 21 patients, 16 underwent unenhanced and contrast-enhanced CT scans; 5 underwent unenhanced and contrast-enhanced MRI ...
Suri Sana S Department of Psychiatry, Warneford Hospital, Warneford Lane, University of Oxford, Oxford, OX3 7JX, - - 2014
Dementia is one of the major causes of personal, societal and financial dependence in older people and in today's ageing society there is a pressing need for early and accurate markers of cognitive decline. There are several subtypes of dementia but the four most common are Alzheimer's disease, Lewy body dementia, ...
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