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Suri Sana S Department of Psychiatry, Warneford Hospital, Warneford Lane, University of Oxford, Oxford, OX3 7JX, - - 2014
Dementia is one of the major causes of personal, societal and financial dependence in older people and in today's ageing society there is a pressing need for early and accurate markers of cognitive decline. There are several subtypes of dementia but the four most common are Alzheimer's disease, Lewy body dementia, ...
Cho Jin Mo JM Department of Neurosurgery, International St. Mary's Hospital, Incheon, Korea. ; Department of Medicine, Graduate School, Yonsei University, Seoul, - - 2014
To achieve maximal safe resection during brain tumor surgery, functional image-merged neuronavigation is widely used. We retrospectively reviewed our cases in which diffusion tensor image (DTI)-merged functional neuronavigation was performed during surgery. Between November 2008 and May 2010, 123 patients underwent surgery utilizing DTI-merged neuronavigation. Anatomical magnetic resonance images (MRI) ...
Meyer Philipp T PT aDepartment of Nuclear Medicine bCentre of Geriatrics and Gerontology cDepartment of Neurology dDepartment of Psychiatry and Psychotherapy, University Hospital Freiburg, Freiburg, - - 2014
To give an update on recent biomarker imaging studies using single-photon emission computed tomography (SPECT) and positron emission tomography (PET) on cognitive impairment in Lewy-body diseases (LBD). Imaging studies of regional cerebral glucose metabolism with [F]fluorodeoxyglucose(FDG)-PET support the concept that Parkinson's disease (PD) with mild cognitive impairment represents a prodromal ...
Loebel Franziska - - 2014
Mutations in isocitrate dehydrogenase (IDH)-present in a distinct subset of human gliomas characterized by younger age and improved prognosis- cause a marked elevation of the metabolite 2-hydroxyglutarate (2HG) [1,2]. This excess production of 2HG represents an ideal biomarker for these gliomas and can be measured with in-vivo magnetic resonance spectroscopy ...
Murphy Rory K J - - 2014
Currently, there is no noninvasive method to determine spinal cord integrity after a spinal cord injury (SCI) and, thus, a patient's potential for recovery. This is despite 253 000 people in the United States living with a SCI. Diffusion tensor imaging (DTI) measurement of spinal cord injury is significantly confounded by ...
Padayachy Llewellyn - - 2014
The clinical response of pediatric patients after an ETV remains quite varied. Numerous radiological features correlating with ETV outcome have been described, but there still remains a distinct group of patients in which the outcome of the procedure remains uncertain. We reviewed magnetic resonance imaging (MRI) for all ETVs performed ...
Aarabi Bizhan - - 2014
Evidence presented by the Surgical Timing of Acute Spinal Cord Injury Study (STASCIS) was in favor of early (within 24 hours) spinal cord decompression aimed at improved outcome. The exact definition of decompression and the most favorable surgical technique suitable to offer circumferential release of the subarachnoid space around a ...
Melgar Monica L - - 2014
Incidence of cervical spine injury in cases of childhood non-accidental trauma (NAT) is unknown. To help guide the evaluation of children suspected of NAT, we examined our database to determine the incidence of cervical spine injury in these patients. A single-center Institutional Review Board approved retrospective chart review of patients ...
Leker Ronen R RR Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, - - 2014
Patients presenting with focal neurological symptoms may suffer from ischemic stroke, intracerebral hemorrhage, or stroke mimics. Such patients are usually screened with a noncontrast-enhanced computed tomography to rule out hemorrhage and to detect early signs of ischemia. However, the sensitivity of noncontrast-enhanced computed tomography for acute stroke is far inferior ...
Brinjikji Waleed W 1 Department of Radiology, Mayo Clinic, 200 SW First St, Rochester, MN - - 2014
OBJECTIVE. Previous studies have shown socioeconomic disparities in imaging utilization for both acute and chronic diseases. We studied a nationwide database to determine whether insurance-based disparities exist in the utilization of imaging for acute ischemic stroke. MATERIALS AND METHODS. Inpatients with a primary diagnosis of acute ischemic stroke from November ...
Makino Yohsuke Y 1 Department of Legal Medicine, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, - - 2014
OBJECTIVE. The purpose of this study was to assess the incidence of spinal cord injuries without radiographic abnormalities (SCIWORA) on postmortem MDCT studies and to characterize this entity in detail. MATERIALS AND METHODS. Data from consecutive autopsies from October 2009 through December 2012 were searched, yielding 30 cases of cervical ...
Kim Se Hyung SH From the Department of Radiology, Molecular Imaging Program at Stanford, School of Medicine, Stanford University, 300 Pasteur Dr, Room H1307, Stanford, CA 94305-5621 (S.H.K., A.K., J.K.W.); and Department of Radiology and Institute of Radiation Medicine, Seoul National University Hospital, Seoul, Korea - - 2014
With the introduction of molecularly targeted chemotherapeutics, there is an increasing need for defining new response criteria for therapeutic success because use of morphologic imaging alone may not fully assess tumor response. Computed tomographic (CT) perfusion imaging of the liver provides functional information about the microcirculation of normal parenchyma and ...
Chiavaras Mary M MM Department of Diagnostic Imaging, McMaster University, Hamilton General Hospital, Hamilton, Ontario, Canada (M.M.C., L.B.); and Departments of Radiology (J.A.J.) and Orthopedic Surgery (J.M.L., J.L.), University of Michigan, Ann Arbor, Michigan USA. - - 2014
Abnormalities of the lateral antebrachial cutaneous nerve (LABCN) are associated with antecubital elbow conditions, such as distal biceps brachii tendon tears and traumatic cephalic vein phlebotomy. These can lead to lateral forearm, elbow, and wrist symptoms that can mimic other disease processes. The purpose of this study was to characterize ...
Metser Ur U Joint Department of Medical Imaging, University Health Network, Mount Sinai Hospital and Women's College Hospital, University of Toronto, 610 University Ave., Toronto, ON M5G 2M9, - - 2014
Follicular lymphoma (FL) is the most common indolent lymphoma. Despite the evidence-based utilization of FDG PET/CT in aggressive lymphomas, the utility of PET in FL remains controversial and varies across different jurisdictions. The management of patients with FL differs from aggressive lymphomas and is usually reserved for patients with localized ...
Said Nicholas N Departments of Radiology, Neuroradiology - - 2014
Object The purpose of this study was to investigate whether diffusion tensor imaging (DTI) of the corticospinal tract (CST) is a reliable surrogate for intraoperative macrostimulation through the deep brain stimulation (DBS) leads. The authors hypothesized that the distance on MRI from the DBS lead to the CST as determined ...
Yeh Ren-Hua RH Division of Hematology/Oncology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, - - 2014
Patients with triple-negative breast cancer (TNBC) are at increased risk of brain metastases (BMs). In this retrospective single-institutional study, we assessed the radiographic features from a cohort of breast cancer (BC) patients with confirmed BM. Women diagnosed with BC with BM from January 1, 1996 to May 31, 2012 were ...
McGuire Kandace P KP Department of Surgery, Magee-Womens Hospital, University of Pittsburgh, Pittsburgh, PA, USA, - - 2014
Neoadjuvant chemotherapy (NCT) downstages advanced primary tumors, with magnetic resonance imaging (MRI) being the most sensitive imaging predictor of response. However, the impact of MRI evaluation on surgical treatment decisions in the neoadjuvant setting has not been well described. We report surgical patterns of care across 8 National Cancer Institute ...
Yamaguchi Kyoko K Department of Anesthesiology, Yokohama City University Medical Center, 4-57 Urafune-cho Minami-ku, Yokohama, Kanagawa, 232-0024, Japan, - - 2014
Myxomas are the most common type of cardiac tumor. Mobile or large left atrial (LA) myxomas frequently cause functional mitral stenosis, and can lead to mitral regurgitation (MR). Difficulties have been associated with detecting masked MR jets and evaluating the severity of MR during LA myxoma surgery due to the ...
Jabbarli Ramazan R Department of Neurosurgery, University Hospital of Freiburg, Breisacher Straße 64, D-79106, Freiburg/Breisgau, Germany, - - 2014
CT-angiography gains an increasing role in the initial diagnosis of patients with nontraumatic subarachnoid hemorrhage (SAH). However, the implementation of CT-angiography does not always exclude the necessity of conventional angiography. Our objective was to determine the practical utility and cost-effectiveness of CT-angiography. All patients with nontraumatic subarachnoid hemorrhage admitted to ...
Kuittinen Pekka - - 2014
To evaluate the clinical significance of lateral lumbar spinal canal stenosis (LLSCS), found by magnetic resonance imaging (MRI), through correlating the imaging findings with patient symptoms, walking capacity and electromyography (EMG) measurements. 102 patients with symptoms of LSS referred for operative treatment were studied in this uncontrolled study. Of these ...
Fowler Kathryn J KJ *Department of Radiology, and †Department of Internal Medicine, Gastroenterology Division, Washington University, St Louis, - - 2014
: The assessment of disease location, severity, and complications is critical in guiding the choice of Crohn's disease therapy. Cross-sectional imaging studies have therefore had a paramount role in accurately staging Crohn's disease. Traditionally, computed tomography was the test of choice in confirming/excluding strictures, fistulae, and abscesses. Magnetic resonance imaging ...
Blicher Jakob Udby JU Aarhus University, Aarhus, Denmark Hammel Neurorehabilitation and Research Centre, Aarhus University Hospital, Hammel, Denmark - - 2014
Background and Objective. γ-Aminobutyric acid (GABA) is the dominant inhibitory neurotransmitter in the brain and is important in motor learning. We aimed to measure GABA content in primary motor cortex poststroke (using GABA-edited magnetic resonance spectroscopy [MRS]) and in relation to motor recovery during 2 weeks of constraint-induced movement therapy ...
Mirsky David M DM Children's Hospital Colorado, University of Colorado School of Medicine, Denver, Colo., - - 2014
Fetal magnetic resonance imaging (MRI) is a useful adjunct to ultrasound in the evaluation of neural tube defects. The development of ultrafast imaging techniques has contributed to the increasing clinical use of fetal MRI. This review summarizes the utility, safety and technical aspects of fetal MRI and the role it ...
Anaizi Amjad Nasr AN Department of Neurological Surgery, Georgetown University Hospital, Washington, District of Columbia, United - - 2014
Study Design A retrospective case series evaluating the use of fiducial markers with subsequent computed tomography (CT) or CT myelography for intraoperative localization. Objective To evaluate the safety and utility of preoperative fiducial placement, confirmed with CT myelography, for intraoperative localization of thoracic spinal levels. Summary of Background Data Thoracic spine surgery is ...
Martin M M Department of Radiology, Besançon University Hospital, 3 Boulevard Fleming, 25030, Besançon, - - 2014
The purpose of our study was to analyze the clinical relevance of computerized tomography (CT) in providing the diagnosis of inflammatory appendix mass (IAM) in patients with acute appendicitis. The CT images of 134 patients were reviewed. Two groups of patients were made according to the presence (group 1; n = 21) ...
Ryan Ltc Paul LP Tripler Army Medical Center, Honolulu, HI, USA - - 2014
Latent syndesmotic instability is a common cause of chronic ankle pain. The diagnosis is not readily apparent on static imaging as the fibula remains reduced. The hypothesis of this study was that a previously undescribed novel finding on coronal MRI (lambda sign) is an independent indicator of latent syndesmosis instability. ...
Mohanty Sanjib - - 2014
Understanding the mechanisms underlying the pathophysiology of cerebral malaria in patients with Plasmodium falciparum infection is necessary to implement new curative interventions. While autopsy-based studies shed some light on several pathological events that are believed to be crucial in the development of this neurologic syndrome, their investigative potential is limited ...
Rosado-de-Castro Paulo Henrique PH Paulo Henrique Rosado-de-Castro, Sergio Augusto Lopes de Souza, Lea Mirian Barbosa da Fonseca, Bianca Gutfilen, Departamento de Radiologia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-913, - - 2014
Rheumatoid arthritis (RA) is an autoimmune disease, which is associated with systemic and chronic inflammation of the joints, resulting in synovitis and pannus formation. For several decades, the assessment of RA has been limited to conventional radiography, assisting in the diagnosis and monitoring of disease. Nevertheless, conventional radiography has poor ...
Schieda Nicola N The Ottawa Hospital, Department of Medical Imaging, The University of Ottawa, 1053 Carling Avenue, Ottawa, Ontario, Canada, K1Y 4E9, - - 2014
Segmental enhancement inversion (SEI) is a controversial imaging finding reportedly specific for the diagnosis of renal oncocytoma. The purpose of this study was to re-evaluate SEI using biphasic CT and multiphase MRI. With research ethics board approval, a retrospective analysis of patients with resection or biopsy of oncocytoma or chromophobe ...
Marano Riccardo R Department of Radiological Sciences-Institute of Radiology, Catholic University of Rome, "A. Gemelli" University Hospital, L.go Agostino Gemelli 8, 00168, Rome, Italy, - - 2014
To date, several clinical and multicentre studies have demonstrated the accuracy of perfusion cardiac magnetic resonance to detect ischaemia in comparison with quantitative coronary angiography, other noninvasive diagnostic techniques (single photon emission computed tomography; positron-emission tomography), and invasive haemodynamic measurements (fractional flow reserve). Moreover, the favourable safety profile and increasing ...
Sharma Punit P Department of Nuclear Medicine, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, - - 2014
To determine the prognostic value of (68)Ga-DOTANOC PET/CT in patients with well-differentiated neuroendocrine tumor (NET), and to compare the prognostic value with that of (18)F-FDG PET/CT and other conventional clinicopathological prognostic factors. Data from 37 consecutive patients (age 46.6 ± 13.5 years, 51 % men) with well-differentiated NET who underwent (68)Ga-DOTANOC PET/CT and (18)F-FDG ...
Van Hoyweghen Astrid J L AJ Department of Radiology, Antwerp University Hospital, Wilrijkstraat 10, B-2650, Edegem, Belgium, - - 2014
The aim of this study is to evaluate whether previously reported post-mortem CT findings in drowning can reliably distinguish drowning from asphyxiation by any other manner. Cases (n = 14) were corpses with cause of death determined as drowning by concordant autopsy findings and physical and circumstantial evidence. Controls (n = 11) were corpses ...
Putko Brendan N BN Division of Cardiology, Department of Medicine, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, T6G 2S2, AB, - - 2014
Anderson-Fabry disease (AFD) is a lysosomal storage disease caused by the inappropriate accumulation of globotriaosylceramide in tissues due to a deficiency in the enzyme α-galactosidase A (α-Gal A). Anderson-Fabry cardiomyopathy is characterized by structural, valvular, vascular and conduction abnormalities, and is now the most common cause of mortality in patients ...
Kraguljac Nina Vanessa NV Department of Psychiatry and Behavioral Neurobiology, University of Alabama at - - 2014
Objectives. Abnormalities in resting state connectivity in schizophrenia are now well established, but the biological substrates of these functional alterations remain to be elucidated. Experimental design. We performed a combined functional magnetic resonance imaging (fMRI) and magnetic resonance spectroscopy ((1) H-MRS) study in 22 unmedicated patients with schizophrenia and 22 ...
Kim Harry K W HK Center of Excellence in Hip Disorders (H.K.W.K., K.D.W., V.K., J.B., E.C., C.B., H.I., J.D., A.L., and J.A.H.) and Department of Radiology (M.D.), Texas Scottish Rite Hospital for Children, 2222 Welborn Street, Dallas, TX 75219. E-mail address for H.K.W. Kim: - - 2014
Current radiographic classifications for Legg-Calvé-Perthes disease cannot be applied at the early stages of the disease. The purpose of this study was to quantify the perfusion of the femoral epiphysis in the early stages of Legg-Calvé-Perthes disease with use of perfusion magnetic resonance imaging (MRI) and to determine if the ...
Shiihara Takashi T Department of Neurology, Gunma Children's Medical Center, Gunma 377-8577, Japan. Electronic address: - - 2014
Pelizaeus-Merzbacher disease (PMD), a hypomyelinating leukodystrophy, and the related but less severe allelic spastic paraplegia 2 (SPG2) are caused by mutations in the proteolipid protein 1 (PLP1) gene. Magnetic resonance imaging (MRI) is pivotal for diagnosing these disorders. The severity of PMD/SPG2 varies, and for a milder form of PMD, ...
Bingen Bo B Leiden University Medical Center, Department of Cardiology, Leiden, - - 2014
Termination of atrial fibrillation (AF) by electrical cardioversion (ECV) remains the mainstay of AF treatment in symptomatic patients. Still, energy requirements for successful ECV (the cardioversion threshold [CT]) are well above the pain threshold, and successrate of ECV diminishes during the progression of paroxysmal to chronic AF. Hence, the use ...
Mata-Mbemba Daddy D Tohoku University, Graduate School of Medicine, Diagnostic Radiology, Sendai, Japan ; - - 2014
Intraventricular hemorrhage (IVH) on initial Computed tomography (CT) were reported to predict lesions of diffuse axonal injury (DAI) in the corpus callosum on subsequent magnetic resonance Imaging (MRI). We aimed to examine the relationship between initial CT findings and DAI lesions detected on MRI, and the relationship between the severity ...
Kana Veronika V Institute of Neuropathology, University Hospital of Zurich, Zurich, - - 2014
Children presenting with neuromuscular symptoms are subject to exhaustive investigations. As it is noninvasive, muscle magnetic resonance imaging (MRI) is an important diagnostic tool in children, yet its impact has so far been mainly studied in small groups of genetically defined diseases, where specific MRI patterns are known. To assess ...
Wakasa Satoru S Department of Cardiovascular and Thoracic Surgery, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kita-ku, Sapporo, 060-8638, - - 2014
The surgical strategy for ischemic mitral regurgitation (MR) remains controversial. Ischemic MR is a secondary valve disease caused by left ventricular (LV) remodeling and subsequent papillary muscle displacement, usually without structural valve lesions. Reduction annuloplasty is the standard surgical procedure for this condition, though it cannot clearly provide a survival ...
Antunes Célia C Centro Hospitalar e Universitário de Coimbra, Praceta Prof. Mota Pinto, 3000-075, Coimbra, Portugal, - - 2014
Erdheim-Chester disease (ECD) is a rare, non-Langerhans cell histiocytosis with characteristic radiological and histological features. This entity is defined by a mononuclear infiltrate consisting of lipid-laden, foamy histiocytes that stain positively for CD68 and negatively for CD1a. Osseous involvement is constant and characteristic. Extra-osseous lesions may affect the retroperitoneum, lungs, ...
Möbius Cornelia C From the Departments of Psychiatry, Psychotherapy and Neurology (CM, AK, JK, HHM) and Division of Neuroradiology (TS), Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, - - 2014
We describe a case of intoxication with N-methylamphetamine (Crystal-METH) after withdrawal. Crystal-METH abuse was associated with persisting neurological symptoms and impressive structural white matter alterations. Magnetic resonance imaging should be recommended to document the possible extensive changes in amphetamine abuse, which increases dramatically.
Rockall Andrea G AG Imperial College Healthcare NHS Trust, London, United - - 2014
The role of diffusion weighted MRI (DW-MRI) in ovarian cancer management has been the focus of recent research. In this article, the main research interests and the current and future clinical applications of DW-MRI in ovarian cancer will be discussed. For characterization of complex adnexal masses, the absence of residual ...
Hadid Amir A From the Heller Institute of Medical Research, Sheba Medical Center, Ramat Gan, Israel (A.H., D.S.M., Y.F.); Department of Biomedical Engineering, Tel Aviv University, Tel Aviv, Israel (A.H.); Department of Physiotherapy, Ariel University, Ariel, Israel (D.S.M.); Military Performance Division, U.S. Army Research Institute of Environmental Medicine, Natick, Mass (R.K.E.); Department of Radiology, State University of New York at Stony Brook, Stony Brook, NY (M.E.S.); Department of Imaging, Assaf Harofeh University Medical Center, Israel, Zerifin, Israel (N.S.); and Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pa - - 2014
Purpose To characterize the incidence, location, grade, and patterns of magnetic resonance (MR) imaging findings in the tibia in asymptomatic recruits before and after 4-month basic training and to investigate whether MR imaging parameters correlated with pretraining activity levels or with future symptomatic injury. Materials and Methods This study was ...
Ueda Fumiaki F Department of Radiology, Kanazawa University Hospital, Japan. Electronic address: - - 2014
We present a case of hemihypoplasia of the striatum with ipsilateral cerebral hemispheric atrophy. The head of the caudate nucleus and putamen were hypoplastic, and gray matter cell bridges between them located in the anterior limb of the internal capsule were sparse. Cerebral atrophy was accompanied by ipsilateral mesial temporal ...
Maier-Hein Klaus H KH Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Junior Group Medical Image Computing, German Cancer Research Center, Heidelberg, Germany; Junior Group Quantitative Image-based Disease Characterization, German Cancer Research Center, Heidelberg, Germany. Electronic address: - - 2014
Brain atrophy in subjects with mild cognitive impairment (MCI) introduces partial volume effects, limiting the sensitivity of diffusion tensor imaging to white matter microstructural degeneration. Appropriate correction isolates microstructural effects in MCI that might be precursors of Alzheimer's disease (AD). Forty-eight participants (18 MCI, 15 AD, and 15 healthy controls) ...
Driscoll Dearbhail O DO St. James Hospital, Dublin 8, Dublin, Leinster, Ireland, - - 2014
To assess the clinical benefit of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (18F-FDG-PET/CT) in evaluating pelvic lymph nodes in patients with early stage cervical cancer (FIGO stage 1a-1b1), who have magnetic resonance imaging (MRI)-defined lymph node negative disease, with histopathologic results as the reference standard. We assessed one hundred and seventy ...
De Marchis Gian Marco GM Division of Neurocritical Care, Department of Neurology and Neurosurgery, Columbia University, New York, NY, USA, - - 2014
In subarachnoid hemorrhage (SAH), brain injury visible within 48 h of onset may impact on admission neurological disability and 3-month functional outcome. With volumetric MRI, we measured the volume of brain injury visible after SAH, and assessed the association with admission clinical grade and 3-month functional outcome. Retrospective cohort study conducted ...
Shapiro B B Fischell Department of - - 2014
Magnetic fields have the potential to noninvasively direct and focus therapy to disease targets. External magnets can apply forces on drug-coated magnetic nanoparticles, or on living cells that contain particles, and can be used to manipulate them in vivo. Significant progress has been made in developing and testing safe and ...
Hernandez Leanna M LM 1] Interdepartmental Neuroscience Program [2] Department of Psychiatry and Biobehavioral - - 2014
Neuroimaging investigations of Autism Spectrum Disorders (ASDs) have advanced our understanding of atypical brain function and structure, and have recently converged on a model of altered network-level connectivity. Traditional task-based functional magnetic resonance imaging (MRI) and volume-based structural MRI studies have identified widespread atypicalities in brain regions involved in social ...
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