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O'Connor Stacy D SD 1 Center for Evidence Based Imaging, Brigham and Women's Hospital, Harvard Medical School, 20 Kent St, Second Fl, Brookline, MA - - 2014
OBJECTIVE. The purpose of this study was to determine the impact of requiring clinical justification to override decision support alerts on repeat use of CT. SUBJECTS AND METHODS. This before and after intervention study was conducted at a 793-bed tertiary hospital with computerized physician order entry and clinical decision support ...
Russell David S DS Institute for Neurodegenerative Disorders, New Haven, Connecticut2Molecular NeuroImaging, LLC, New Haven, - - 2014
In Huntington disease (HD) striatal neuron loss precedes and predicts motor signs or symptoms. Current imaging biomarkers lack adequate sensitivity for assessing the early stages of HD. Developing an imaging biomarker for HD spanning the time of onset of motor signs remains a major unmet research need. Intracellular proteins whose ...
Lei Bing-Hsuan BH Interdisciplinary MRI/MRS Lab, Graduate Institute of Electrical Engineering, National Taiwan University; National Taiwan University Molecular Imaging - - 2014
Manganese-enhanced magnetic resonance imaging (MEMRI) has been extensively used in studying the structural and functional features of the central nervous system (CNS). Divalent manganese ion (Mn(2+)) not only enhances MRI contrast, but also enters cells via voltage-gated calcium channels or ionotropic glutamate receptors, which represents an index of neural activities. ...
Lee Yedaun Y From the Department of Radiology and Research Institute of Radiology (Y.L., S.S.L., N.K., E.K., Y.J.K., S.H.P., S.Y.K., M.G.L.) and Department of Clinical Epidemiology and Biostatistics (S.C.Y.), University of Ulsan College of Medicine, Asan Medical Center, 86 Asanbyeongwon-Gil, Songpa-Gu, Seoul 138-736, South Korea; Siemens AG, Healthcare, Oncology Applications Development, Erlangen, Germany (B.K.); and Siemens Healthcare Korea, Seoul, South Korea - - 2014
Purpose To compare the influence of triggering methods for diffusion-weighted imaging (DWI) on apparent diffusion coefficient (ADC) and intravoxel incoherent motion (IVIM) parameters in the liver, as well as regional variability and measurement repeatability. Materials and Methods In this institutional review board-approved prospective study, 12 healthy volunteers (six women, six ...
Cho A R AR Department of Ophthalmology, Ewha Womans University Medical Center, School of Medicine, Seoul, Republic of - - 2014
PurposeTo determine the influence of choroidal thickness (CT) and image setting on repeatability of subfoveal choroidal thickness (SFCT) manual measurement using enhanced depth imaging optical coherence tomography (EDI-OCT).MethodsThis retrospective study included 189 eyes from 189 adults. Two observers (A and B) measured the SFCT from 1 : 1 micron and 1 : 1 pixel ...
O'Sullivan Brian B Department of Pediatrics, University of Massachusetts Medical School, Worcester, - - 2014
Hyperpolarized (HP) gas magnetic resonance imaging (MRI) is an advanced imaging technique that provides high-resolution regional information on lung function without using ionizing radiation. Before this modality can be considered for assessing clinical or investigational interventions, baseline repeatability needs to be established. We assessed repeatability of lung function measurement using ...
Gelfand Michael J MJ Section of Nuclear Medicine, Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA, - - 2014
In Langerhans cell histiocytosis (LCH), FDG PET demonstrates active disease in bone. Other imaging modalities show the effects of bone destruction by LCH. To evaluate a selective CT method for reducing effective dose from FDG PET/CT in LCH, using whole-body modified attenuation correction CT at extremely low exposure settings, with ...
Samarghandi Amin A From the *Division of Nuclear Medicine, Department of Radiology, The Ohio State University Wexner Medical Center; †Department of Radiology, Nationwide Children's Hospital, Columbus, OH; ‡Department of Pathology, Texas Children's Hospital and Baylor College of Medicine, Houston, - - 2014
An 11-year-old girl presented with abnormal weight gain and was found to have hepatomegaly. MRI of the abdomen revealed a 20-cm hepatic mass. F-FDG PET/CT showed a large hypermetabolic calcified hepatic mass and couple of mildly hypermetabolic pulmonary nodules with associated intrathoracic lymphadenopathy. Liver biopsy was consistent with nested stromal ...
Kukuk Guido M GM Department of Radiology, University of Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany, - - 2014
To evaluate hepatobiliary magnetic resonance imaging (MRI) using Gd-EOB-DTPA in relation to various liver function tests in patients with liver disorders. Fifty-one patients with liver disease underwent Gd-EOB-DTPA-enhanced liver MRI. Based on region-of-interest (ROI) analysis, liver signal intensity was calculated using the spleen as reference tissue. Liver-spleen contrast ratio (LSCR) ...
Bhandari Virendra V Department of Radiotherapy, Sri Aurobindo Institute of Medical Sciences, Indore, Madhya Pradesh, - - 2014
Anatomical changes can occur during course of head-and-neck (H and N) radiotherapy like tumor shrinkage, decreased edema and/or weight loss. This can lead to discrepancies in planned and delivered dose increasing the dose to organs at risk. A study was conducted to determine the volumetric and dosimetric changes with the ...
Powerski Maciej Janusz MJ Department of Radiology and Nuclear Medicine, Otto-von-Guericke University, - - 2014
To evaluate the uptake of the liver-specific magnetic resonance imaging (MRI) contrast agent gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) by functional liver parenchyma after radioembolisation (RE) of hepatic malignancies. Uptake of Gd-EOB-DTPA prior to RE versus 60+/-24d and 126+/-32d after RE was compared in a group of 33 patients with ...
Han Kichang K *Department of Radiology and Research Institute of Radiology †Department of Colorectal Surgery ‡Department of Medical Education and Support, University of Ulsan College of Medicine, Asan Medical Center, Seoul, - - 2014
To investigate the impact of liver magnetic resonance imaging (MRI) in staging evaluation of newly diagnosed colorectal cancer patients. No clear guidelines regarding how to use liver MRI in evaluating newly diagnosed colorectal cancer. We included 863 adults who had newly diagnosed colorectal cancer without concomitant malignancies and received portal-phase ...
Nardini Giordano - - 2014
Contrast-enhanced diagnostic imaging techniques are considered useful in veterinary and human medicine to evaluate liver perfusion and focal hepatic lesions. Although hepatic diseases are a common occurrence in reptile medicine, there is no reference to the use of contrast-enhanced ultrasound (CEUS) and contrast-enhanced computed tomography (CECT) to evaluate the liver ...
Revheim Mona-Elisabeth ME Department of Radiology and Nuclear Medicine, Oslo University Hospital, - - 2014
Detection of small liver metastases from colorectal cancer by 18F-FDG PET/CT is hampered by high physiologic uptake in the liver parenchyma and respiratory movements during image acquisition. To investigate whether two tailored 18F-FDG PET liver acquisitions (prolonged liver acquisition time [PL-PET] and repeated breath-hold respiratory gated liver acquisition [RGL-PET]) would ...
Haimerl Michael M Department of Radiology, University Hospital Regensburg, Regensburg, - - 2014
Gd-EOB-DTPA is a hepatocyte-specific MRI contrast agent. Due to its hepatocyte-specific uptake and paramagnetic properties, functioning areas of the liver exhibit shortening of the T1 relaxation time. We report the potential use of T1 relaxometry of the liver with Gd-EOB-DTPA-enhanced magnetic resonance imaging (MRI) for estimating the liver function as ...
Tripuraneni Vinay V Medical Scientist Training Program, Duke University School of Medicine, Duke University Medical Center, Durham, NC, - - 2013
We report the case of a previously healthy 21-year-old woman who presented 6 days post-partum in acute fulminant hepatic failure. A liver ultrasound demonstrated normal echogenicity without discrete nodules while an enhanced computed tomography (CT) demonstrated innumerable 1- to 3-mm hypodense nodules throughout the liver with greater involvement of the ...
Kang Tae Wook - - 2013
Objectives- The purpose of this study was to assess the coverage of transverse subcostal sonography in the supine position by using computed tomography (CT) performed before a sonographic liver examination as a predictor of sonographic coverage. Methods- A total of 124 patients (87 men and 37 women; mean age, 55.55 ...
Roos P - - 2013
The SPG5A subtype of Hereditary Spastic Paraplegia (HSP) is a rare autosomal recessive neurodegenerative disorder caused by mutations in the CYP7B1 gene, which encodes a steroid cytochrome P450 7α-hydroxylase. This enzyme provides the primary metabolic route for neurosteroids. Clinically, SPG5A has been characterized as a pure form of HSP with ...
Cha Dong Ik - - 2013
To determine the added value of 3 Tesla liver MR in patients with hepatocellular carcinoma (HCC) within the liver computed tomography (CT) -based Milan criteria. Liver CT and MR images of 130 patients with HCC within the Milan criteria based on liver CT were retrospectively reviewed. The number of MR-diagnosed ...
Onishi Hiromitsu H Institute for Clinical Radiology, Ludwig Maximilians-University Hospital Munich, Germany; Department of Radiology, Osaka University Graduate School of Medicine, Osaka, - - 2014
To investigate the effect of hepatic steatosis on enhancement of liver parenchyma with gadoxetate disodium-enhanced MR imaging. Gadoxetate disodium-enhanced MR images of 166 patients were analyzed. Liver-spleen contrast and liver-spleen relative enhancement ratio on three-dimensional gradient echo T1-weighted images with fat suppression 20 minutes after injection of gadoxetate disodium were ...
Tam H H HH Department of Radiology, Royal Marsden Hospital, Sutton, UK. - - 2013
To determine the prognostic value of pre-treatment apparent diffusion coefficient (ADC) of colorectal liver metastases in predicting disease response, progression-free survival (PFS) and overall survival (OS). We retrospectively reviewed 102 patients who underwent pre-treatment diffusion-weighted MRI using a breath-hold (b=0, 150, 500) or a free-breathing (b=0, 50, 100, 250, 500, ...
Dohan Anthony - - 2013
To qualitatively and quantitatively compare T2-weighted MR imaging of the liver using volumetric spin-echo with sampling perfection with application-optimized contrast using different flip angle evolutions (SPACE) with conventional turbo spin-echo (TSE) sequence for fat-suppressed T2-weighted MR imaging of the liver. Thirty-three patients with suspected focal liver lesions had SPACE MR ...
Suzuki Kenji - - 2013
Computerized liver volumetry has been studied, because the current "gold-standard" manual volumetry is subjective and very time-consuming. Liver volumetry is done in either CT or MRI. A number of researchers have developed computerized liver segmentation in CT, but there are fewer studies on ones for MRI. Our purpose in this ...
Jeng K-S - - 2013
Early detection of Budd-Chiari syndrome (BCS) to give the appropriate therapy in time is crucial. Angiography remains the golden standard to diagnose BCS. However, to establish the diagnosis of BCS in complicated cirrhotic patients remains a challenge. We used maximum intensity projection (Max IP) and minimum intensity projection (Min IP) ...
Goumard Claire - - 2013
OBJECTIVES: The estimation of liver volume (LV) has been widely studied in normal liver, the density of which is considered to be equivalent to 1 kg/l. In cirrhosis, volumetric evaluation and its correlation to liver mass remain unclear. The aim of this study was to evaluate the accuracy of computed tomography ...
Cavailloles Françoise Annie - - 2013
We report a case of liver amoebic abscesses in a 58-year-old man referred for a FDG PET/CT with an initial diagnosis of secondary hepatic lesions. This patient, coming from Sri Lanka, presented with fever and shivers, pain in the right flank, vomiting, and diarrhea for a month. The FDG PET/CT ...
de Souza Daniel Andrade Tinoco - - 2013
Modern MR imaging evaluation of the liver allows for a comprehensive morphologic and functional assessment of the liver parenchyma, hepatic vessels, and biliary tree, thus aiding in the diagnosis of both focal and diffuse liver diseases.
Nilsson H H Division of Surgery, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Stockholm, Sweden. - - 2013
The aims of this study were to use dynamic hepatocyte-specific contrast-enhanced MRI to evaluate liver volume and function in liver cirrhosis, correlate the results with standard scoring models and explore the inhomogeneous distribution of liver function in cirrhotic livers. 10 patients with liver cirrhosis and 20 healthy volunteers, serving as ...
Idilman Ilkay S - - 2013
Purpose:To determine utility of proton density fat fraction (PDFF) measurements for quantifying the liver fat content in patients with nonalcoholic fatty liver disease (NAFLD), and compare these results with liver biopsy findings.Materials and Methods:This retrospective study was approved by the institutional review board with waivers of informed consent. Between June ...
Parikh Ankur - - 2013
Hepatocellular carcinoma (HCC) is the most common primary hepatic malignancy, and usually develops in the setting of liver cirrhosis. The early diagnosis of HCC is essential as curative treatment (including surgical resection and liver transplantation) improves survival. While screening and surveillance are traditionally performed with ultrasound, reported accuracies of ultrasound ...
Mendonça Paulo R S PR GE Global Research, One Research Circle, Niskayuna, NY 12309, USA. - - 2013
The diagnosis and treatment of fatty liver disease requires accurate quantification of the amount of fat in the liver. Image-based methods for quantification of liver fat are of increasing interest due to the high sampling error and invasiveness associated with liver biopsy, which despite these difficulties remains the gold standard. ...
Tsin Daniel Alberto DA The Mount Sinai Hospital of Queens, Long Island City, NY, USA. - - 2013
A novel technique was used to remove a large liver cyst via culdolaparoscopy. We used laparoscopic instruments, a gastroscope, a laparoscopic rein, and magnets. The magnets consist of an external magnet and a specially modified tethered neodymium internal magnet, safe for use in transvaginal endoscopic surgery. These technologies offer some ...
Motosugi Utaroh - - 2012
The aim of this study was to examine liver stiffness value measured by magnetic resonance elastography (MRE) and laboratory test results to find the best method for predicting insufficient liver enhancement on gadoxetic acid-enhanced hepatocyte-phase images. The institutional ethics committee approved this retrospective study with waiver of informed consent. In ...
Ozaki Masanori - - 2012
PURPOSE: To assess the effect of motion artifact reduction on the diffusion-weighted magnetic resonance imaging (DWI-MRI) of the liver, we compared velocity-compensated DWI (VC-DWI) and VC-DWI combined with tetrahedral gradients (t-VC-DWI) to conventional DWI (c-DWI) in the assessment of apparent diffusion coefficients (ADCs) of the liver. MATERIALS AND METHODS: In ...
Busard Milou P H - - 2012
To evaluate magnetic resonance (MR) imaging morphologic- and signal intensity abnormalities of deep infiltrating endometriosis (DIE) of the bowel wall and to assess its value in predicting depth and extent of bowel wall infiltration. This single-center study was performed in a tertiary referral center for endometriosis. All patients (n = ...
Dang Lei - - 2012
Vertebral hemangioma (VH) is virtually vascular malformation, which is usually asymptomatic. Only 3.7 % of VH may become active and symptomatic, and 1 % may invade the spinal canal and/or paravertebral space. Treatment protocols for active or aggressive VHs are still in controversy. Reported treatments include radiotherapy, vertebroplasty, direct alcohol injection, embolization, ...
Albiin Nils - - 2012
Magnetic resonance imaging, MRI has more advantages than ultrasound, computed tomography, CT, positron emission tomography, PET, or any other imaging modality in diagnosing focal hepatic masses. With a combination of basic T1 and T2 weighted sequences, diffusion weighted imaging, DWI, and hepatobiliary gadolinium contrast agents, that is gadobenate dimeglumine (Gd-BOPTA) ...
Ryou Hong Sun - - 2012
Vessel geometry for numerical analysis is generally obtained by computed tomography (CT) or magnetic resonance imaging (MRI) and intravascular ultrasound (IVUS). Most medical imaging is obtained from patients for hemodynamic analysis due to the properties of vascular disease and the difficulties in angiography. To predict the site where plaque occurs ...
Papadopoulou Stella-Lida - - 2012
AIMS: We evaluated the distribution and composition of atherosclerotic plaques at bifurcations with intravascular ultrasound-virtual histology (IVUS-VH) and multidetector computed tomography (MDCT) in relation to the bifurcation angle (BA). METHODS AND RESULTS: In 33 patients (age 63 ± 11 years, 79% male) imaged with IVUS-VH and MDCT, 33 bifurcations were ...
Amemura-Maekawa Junko - - 2012
Legionella pneumophila serogroup (SG) 1 is the most frequent cause of legionellosis. This study analyzed environmental isolates of L. pneumophila SG 1 in Japan using monoclonal antibody (MAb) typing and sequence-based typing (SBT). Samples were analyzed from bathwater (BW; n = 50), cooling tower water (CT; n = 50), and ...
Stein Lauren - - 2012
A 36-year-old woman presented to her primary care physician with right lower abdominal pain. Her physician subsequently requested a CT to rule out appendicitis. Contrast-enhanced CT was performed and revealed no evidence of appendicitis but showed two subcutaneous ovoid soft-tissue masses anterior to the rectus sheath in the upper pelvis. ...
Tartaglione T - - 2012
PURPOSE: The aim of this paper is to demonstrate that computed tomography (CT) and three-dimensional (3D) CT imaging techniques can be useful tools for evaluating gunshot wounds of the skull in forensic medicine. Three purposes can be achieved: (1) identifying and recognising the bullet entrance wound - and exit wound, ...
Saccardi Carlo - - 2012
Objective: to compare clinical evaluation, transvaginal ultrasound, sonovaginography and magnetic resonance imaging in the diagnosis of posterior deep pelvic endometriosis. Methods: women suspected of having posterior deep pelvic endometriosis on the basis of subjective symptoms and clinical evaluation, underwent clinical evaluation, transvaginal ultrasound, sonovaginography and magnetic resonance imaging. Laparoscopy was ...
Wu Teresa S - - 2012
OBJECTIVE: The primary purpose of this study was to investigate the overall accuracy of bedside extremity tendon ultrasound performed by emergency physicians in the emergency department. We also sought to investigate whether or not bedside tendon ultrasonography can be used to expedite the diagnosis and discharge planning in patients with ...
Kanematsu Masayuki - - 2012
Diffusion-weighted (DWI) magnetic resonance (MR) imaging is useful in diagnosing various pathologic conditions in the liver, such as malignant tumors or hepatic fibrosis, and is now part of routine MR imaging protocols for the liver following the development of a parallel encoding technique that has markedly improved image quality. DWI ...
Saba Luca - - 2011
PURPOSE: To compare the diagnostic accuracy of MRI and "tenderness-guided" transvaginal ultrasonography (tg-TVUS) in the identification of recto-sigmoid endometriosis. MATERIALS AND METHODS: Institutional Review Board approval for this study was obtained, and written informed consent was given by all patients. This study is compliant with the STARD (Standards for Reporting ...
Sano Rie - - 2011
A 53-year-old man was found dead after a fire at his residence had been extinguished. Although a pistol was recovered beside the body, external examination was unable to indicate any gunshot wound because of severe charring of the body. Postmortem computed tomography (CT) scan performed prior to autopsy suggested an ...
Daperno Marco - - 2011
The healing of the intestine is becoming an important objective in the management of inflammatory bowel diseases. It is associated with improved disease outcome. Therefore the assessment of this healing both in clinical studies and routine practice is a key issue. Endoscopy for the colon and terminal ileum and computerized ...
Busard M P H - - 2011
OBJECTIVE: Both the intraperitoneal seeding and the uterine-vesical extension theory have been proposed to explain the pathogenesis of bladder endometriosis. The aim of this study was to describe MR imaging findings of bladder endometriosis and involvement of the anterior uterine wall in a tertiary referral centre for endometriosis in a ...
Chamié Luciana Pardini - - 2011
Endometriosis is a common multifocal gynecologic disease that manifests during the reproductive years, often causing chronic pelvic pain and infertility. It may occur as invasive peritoneal fibrotic nodules and adhesions or as ovarian cysts with hemorrhagic content. Although findings at physical examination may be suggestive, imaging is necessary for definitive ...
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