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Lee Ricky W RW Department of Neurology, Mayo Clinic, Rochester, MN, United - - 2014
We evaluated the outcomes of intracranial electroencephalography (iEEG) recording and subsequent resective surgery in patients with magnetic resonance imaging (MRI)-negative temporal lobe epilepsy (TLE). Thirty-two patients were identified from the Mayo Clinic Epilepsy Surgery Database (Arizona, Florida, and Minnesota). Eight (25.0%) had chronic iEEG monitoring that recorded neocortical temporal seizure ...
Laothamatas Jiraporn J Department of Radiology, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand; Lurie Children's Hospital of Chicago, Chicago, Illinois; Institute of Neurology, University College London, London, United Kingdom; Philips Healthcare, Best, The Netherlands; The Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; Departments of Radiology and Pediatrics and Medicine, Columbia University College of Physicians and Surgeons, New York, New York; Medical University of South Carolina, Charleston, South - - 2014
Patients with acute uncomplicated Plasmodium falciparum malaria have no evident neurologic disorder, vital organ dysfunction, or other severe manifestations of infection. Nonetheless, parasitized erythrocytes cytoadhere to the endothelium throughout their microvasculature, especially within the brain. We aimed to determine if 3 Tesla magnetic resonance imaging studies could detect evidence of ...
Kovac Stjepana S *Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, United Kingdom; †Department of Neurology, University of Muenster, Muenster, Germany; ‡Telemetry Unit, National Hospital for Neurology and Neurosurgery, London, United Kingdom; and §BESA GmbH, Grafelfing/Munich, - - 2014
To investigate the utility of EEG source imaging to lateralize ictal patterns in frontal lobe epilepsy, which were nonlateralized by standard EEG analysis. Prospective analysis of 17 seizures in 8 patients with unilateral frontal lobe epilepsy MRI lesions and nonlateralizing ictal scalp EEG. We applied four EEG source imaging techniques ...
Cherian Ajith A Department of Neurology, Medical College Hospital, Trivandrum, Kerala, - - 2014
Background: Epilepsy with myoclonic absences (EMAs) is a distinct form of childhood epilepsy characterized by a peculiar seizure type that identifies this condition. Purpose: To describe the clinical, electroencephalographic features, treatment strategies and outcome in this first case series of two siblings with normal intelligence presenting with EMAs. Materials and ...
Miyaji Yosuke Y Department of Neurology and Stroke Medicine, Yokohama Sakae Kyosai Hospital, - - 2014
Arterial spin labeling (ASL) is a non-invasive modality of magnetic resonance imaging (MRI) used to evaluate cerebral perfusion without a contrast agent. The usefulness of ASL for diagnosis in the acute phase of late seizure after stroke was evaluated. Twelve consecutive patients diagnosed with late seizure after stroke were enrolled ...
Shah Divyen K DK Royal London Hospital, , London, - - 2014
Seizures are common among newborns with hypoxic-ischaemic encephalopathy (HIE) but the relationship between seizure burden and severity of brain injury among neonates receiving therapeutic hypothermia (TH) for HIE is unclear. We tested the hypothesis that seizure burden is associated with cerebral tissue injury independent of amplitude-integrated EEG (aEEG) background activity. ...
Yang Kang K Department of Neurosurgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116044, P.R. - - 2014
The present study describes the case of a 27-year-old, right-handed female with bilateral mesial temporal lobe epilepsy. Electroencephalogram (EEG) monitoring from implanted electrodes displayed two different and independent onsets on the two sides of the mesial temporal structures, which specifically included clinical generalized tonic clonic seizure (GTCS) discharges originating from ...
Nooraine Javeria J Department of Neurology, Vikram Hospital, Bengaluru, Karnataka, - - 2013
Ictal Pet in presurgical workup of refractory epilepsy is seldom performed and limited due to technical difficulties. In carefully selected patient subset with frequent extratemporal seizures, ictal PET depicts 'seizure onset zone' with high spatial resolution even within a widespread pathology. We here depict a four year old with posterior ...
Bhattacharjee Shakya S Department of Neurology, Mater Misericordaie University Hospital, Dublin - 7, - - 2013
Our present observational study attempted to evaluate the clinical profiles, diagnosis, treatment and follow-up results of 51 pediatric neurocysticercosis patients over a mean duration of five years (from January 2006 to December 2010). Diagnosis was mainly based on clinical features, computed tomography (CT)/magnetic resonance imaging scan and exclusion of other ...
Tepmongkol Supatporn - - 2013
Bilateral temporal lobe hypometabolism (BTH) on (18)F-FDG PET brain scan is frequently seen in unilateral medial temporal lobe epilepsy (mTLE). This study aimed to identify the factors that influence BTH in patients with mTLE in order to minimize the significant factor(s) prior to performing a FDG-PET brain scan. Forty patients ...
Jung Julien J 1 Lyon Neuroscience Research Centre, INSERM U1028, CNRS UMR5292, Brain Dynamics and Cognition Team, Lyon, F-69000, - - 2013
Surgical treatment of epilepsy is a challenge for patients with non-contributive brain magnetic resonance imaging. However, surgery is feasible if the seizure-onset zone is precisely delineated through intracranial electroencephalography recording. We recently described a method, volumetric imaging of epileptic spikes, to delineate the spiking volume of patients with focal epilepsy ...
Ostendorf Adam P - - 2013
To describe the clinical characteristics and outcomes of individuals with neurofibromatosis type 1 (NF1) and seizures in the largest cohort reported to date. A retrospective cross-sectional review of 536 individuals with NF1 was performed, and clinical data from 51 individuals with a history of at least one seizure were analyzed. ...
Chhetri Suresh Kumar - - 2013
Non-convulsive status epilepticus (NCSE) can present with heterogeneous clinical manifestations including prolonged confusion. MRI of the brain may demonstrate enhancing signal abnormalities that can mimic various pathologies including disease progression in patients with brain tumour. These neuroimaging changes are usually reversible and have been attributed to a combination of cytotoxic ...
Cianfoni A - - 2013
Introduction MRI abnormalities in the postictal period might represent the effect of the seizure activity, rather than its structural cause. Material and Methods Retrospective review of clinical and neuroimaging charts of 26 patients diagnosed with seizure-related MR-signal changes. All patients underwent brain-MRI (1.5-Tesla, standard pre- and post-contrast brain imaging, including ...
Alkawadri Rafeed - - 2013
IMPORTANCE The literature on cingulate gyrus epilepsy in the magnetic resonance imaging era is limited to case reports and small case series. To our knowledge, this is the largest study of surgically confirmed epilepsy arising from the anterior or posterior cingulate region. OBJECTIVE To characterize the clinical and electrophysiological findings ...
See Siew-Ju - - 2013
BACKGROUND:: Surgery is an important therapeutic option in patients with medically refractory epilepsy. The combination of an extratemporal epileptic focus and non-lesional MRI was often believed to portend a poor outcome. OBJECTIVE:: To investigate the outcome and analyze potential prognostic predictors in patients without lesions on MRI who underwent extratemporal ...
McTague Amy - - 2013
Migrating partial seizures of infancy, also known as epilepsy of infancy with migrating focal seizures, is a rare early infantile epileptic encephalopathy with poor prognosis, presenting with focal seizures in the first year of life. A national surveillance study was undertaken in conjunction with the British Paediatric Neurology Surveillance Unit ...
Boyle Deborah A - - 2013
BACKGROUND: Complex febrile seizures (CFSs) are a common diagnosis in the pediatric emergency department (PED). Although multiple studies have shown a low likelihood of intracranial infections and abnormal neuroimaging findings among those who present with CFS, the absence of a consensus recommendation and the diversity of CFS presentations (ie, multiple ...
Immonen Riikka - - 2013
The present study tested a hypothesis that early identification of injury severity with quantitative magnetic resonance imaging (MRI) provides biomarkers for predicting increased seizure susceptibility and epileptogenesis after traumatic brain injury (TBI). TBI was induced by lateral fluid-percussion injury in adult rats. Quantitative T2, T1ρ, and diffusion were assessed with ...
Srinivasakumar Preethi - - 2013
OBJECTIVE: To evaluate the electrographic seizure burden in neonates with hypoxic ischemic encephalopathy (HIE) treated with or without therapeutic hypothermia and stratified results by severity of HIE and severity of injury as assessed by magnetic resonance imaging (MRI). STUDY DESIGN: Between 2007 and 2011, video-electroencephalography (EEG) monitoring was initiated in ...
O'Connor Lucy - - 2013
The authors present the rare case of complete image-defined resolution of a hypothalamic hamartoma (HH) following Gamma Knife surgery (GKS). A 9-month-old girl presented with an episode of generalized tonic-clonic seizures. Magnetic resonance imaging revealed a left-sided HH, which remained radiologically stable. By 3 years of age the patient had ...
Mumcuoğlu Erkan U EU Health Informatics Department, Informatics Institute, Middle East Technical University, Ankara, Turkey. - - 2013
Cystic fibrosis (CF) is a life-limiting genetic disease that affects approximately 30,000 Americans. When compared to those of normal children, airways of infants and young children with CF have thicker walls and are more dilated in high-resolution computed tomographic (CT) imaging. In this study, we develop computer-assisted methods for assessment ...
Domachevsky Liran - - 2013
Hyperbaric oxygen-induced seizures are classified as generalized, tonic-clonic seizures. They are believed to cause no residual neurologic damage, although this has not been investigated in depth. We used different MRI sequences to determine whether hyperbaric oxygen-induced seizures in mice caused brain structural changes. Experimental animals were exposed to a pressure ...
Shrestha Balkrishna - - 2013
A rare syndrome, Dyke-Davidoff-Masson Syndrome (DDMS), with a diagnostic conundrum, and the way it was solved is presented. A 13-yearold boy presented with recurrent seizures for the past 10 years. He had been treated with anticonvulsant medication which was satisfactory at first but later the seizures recurred. Recently, the frequency ...
Molla Mohammadi Mohsen M Pediatric Neurology Research Center, Qom University of Medical Sciences, Qom, - - 2013
Seizure is an emergency in pediatrics. It really matters to the parents of the involved child to have information about the causes, management and prognosis. First unprovoked seizures (FUS) are seizures that occur in patients without fever, trauma or infection. Due to the rapid improvement in diagnostic techniques in the ...
Kadom N - - 2012
SUMMARY:Failure to detect FCD and similar lesions encountered in patients with tuberous sclerosis can have significant clinical consequences, such as preventing surgical intervention for medically refractory epilepsy and misguiding prognostic information regarding cognitive development. Here, we show the beneficial effects on detection of FCD and cortical tubers when using a ...
Al-Rumayyan Ahmed R - - 2012
To estimate the prevalence of abnormal neuroimaging in children presenting to the emergency department (ED) with a new-onset seizure, and to identify the significant clinical predictors for an abnormal CT scan. In this cross-sectional study, all children age 12 or younger, admitted to the ED at King Abdulaziz Medical City ...
Kriegel Matthias F - - 2012
: Orbitofrontal and insular epilepsy are difficult to recognize because clinical presentations are variable and surgical approaches remain difficult. : Literature review and review of our own case series including selected cases regarding the clinical manifestation and diagnostic utility of diagnostic tests in orbitofrontal and insular epilepsy. : Orbitofrontal epilepsy ...
Sinha Sanjib - - 2012
The occurrence of epilepsy is higher among elderly patients. The clinical manifestations of seizures, causes of epilepsy, and choice of anti-epileptic drugs (AEDs) are different in elderly people with epilepsy compared to the young. To evaluate the imaging (CT/MRI) observations in elderly patients manifesting with new-onset seizures. Two hundred and ...
Lee Ricky W - - 2012
Dorsolateral frontal lobe seizures often present as a diagnostic challenge. The diverse semiologies may not produce lateralizing or localizing signs and can appear bizarre and suggest psychogenic events. Unfortunately, scalp electroencephalographic (EEG) and magnetic resonance imaging (MRI) are often unsatisfactory. It is not uncommon that these traditional diagnostic studies are ...
Cheng Gang - - 2012
ABSTRACT: A 69-year-old man with a lung mass underwent multiple-time-point FDG PET/CT imaging for diagnostic evaluation. The initial PET imaging (performed at 1 hour after tracer injection) revealed equivocal bone marrow uptake in the right iliac bone and proximal femurs in addition to lung and mediastinal lesions. The 3-hour delayed ...
Al-Shahi Salman Rustam R Division of Clinical Neurosciences, Centre for Clinical Brain Sciences, School of Clinical Sciences, University of Edinburgh, Edinburgh, United Kingdom. - - 2012
Cerebral cavernous malformations (CCMs) and arteriovenous malformations (AVMs) are common: their asymptomatic prevalence on brain magnetic resonance imaging (MRI) is 1 in 625 and 1 in 2,000, respectively. The risk of epileptic seizure(s) for people with AVMs and CCMs affects their domestic, social, and professional lives, and may influence their ...
Brigo Francesco - - 2012
Seizures may frequently occur during tuberculous meningitis. We describe a patient with an apparent generalised tonic-clonic seizure, initially not associated with any magnetic resonance imaging (MRI) abnormality, which was the presenting symptom of tuberculous meningitis. Follow-up MRI, performed after gadolinium administration, showed signs of meningeal involvement. Seizures may be the ...
Costella Stephen - - 2012
SUMMARY AT A GLANCE: We report regional pulmonary functional and micro-structural (3) He magnetic resonance imaging measurements in asthmatic and healthy volunteers before, during and after a methacholine challenge (MCh). Post-MCh, we observed regional alterations in surrogate measurements of bronchoconstriction ((3) He MRI VDP) and gas trapping (ADC). ABSTRACT: Background ...
Aliverti A - - 2012
To study regional lung function by standard CT and characterize regional variations of density and specific gas volume (SVg) between different lung volumes, we studied 10 healthy and 10 severe emphysematous subjects. Correspondent CT images taken at high and low lung volumes were registered by optical flow to obtain 2-D ...
Iguchi Satoshi - - 2012
MRI of hyperpolarized (129) Xe dissolved in pulmonary tissues, and blood has the potential to offer a new tool for regional evaluation of pulmonary gas exchange and perfusion; however, the extremely short T 2* and low magnetization density make it difficult to acquire the image. In this study, an ultrashort echo-time ...
Yu Naichang - - 2013
To propose a new method to estimate lung mean dose (LMD) using technetium-99m labeled macroaggregated albumin ((99m)Tc-MAA) single photon emission CT (SPECT)/CT for (90)Yttrium radioembolization of liver tumors and to compare the LMD estimated using SPECT/CT with clinical estimates of LMD using planar gamma scintigraphy (PS). Images of 71 patients ...
Iwatani Kazuhiro - - 2012
OBJECTIVES: Rubber dams increase the quality and safety of dental treatment. However, the condition of a rubber dam over an open mouth may also obstruct the route for respiration. We tested whether an open mouth with or without a rubber dam would affect upper airway patency and breathing pattern. MATERIALS ...
Caruso Settimo - - 2012
Colonic wall redundancy (CWR) is a condition often seen in adult cystic fibrosis patients, but the imaging features of this condition are poorly described in the literature. Recognizing the radiological presentation of CWR is important because this condition can be confused with acute or acquired colonic diseases that can require ...
Dang Chun-Jiang - - 2012
ABSTRACT: Pulmonary mucormycosis is a life-threatening opportunistic mycosis that is difficult to diagnose early. We report the case of a 56-year-old woman who complained of intermittent fever in the afternoon and productive cough and pain on the right side of the chest. Her clinical condition deteriorated despite antibiotherapy. FDG PET/CT ...
Mets Onno M - - 2012
The purpose of our study was to assess the normal range of CT measures of emphysema and air trapping in young men with normal lung function. A cohort of 70 young men with high-normal spirometry and body plethysmography underwent paired inspiratory and expiratory CT. Visual and quantitative scores of emphysema ...
Greenberg S Bruce - - 2012
Wide-detector CT allows simultaneous imaging of the entire airway and lungs in small children. Images acquired in multiple phases by continuous scanning during respiration are viewed dynamically, allowing more complete airway and pulmonary evaluation than possible with static protocols. The purpose of this study was to evaluate whether low-dose techniques ...
Meng Xin - - 2012
Automated lung volume segmentation is often a preprocessing step in quantitative lung computed tomography (CT) image analysis. The objective of this study is to identify the obstacles in computerized lung volume segmentation and illustrate those explicitly using real examples. Awareness of these "difficult" cases may be helpful for the development ...
Bahl Gautam - - 2012
PURPOSE: To demonstrate a proof of concept that quantitative texture feature analysis of double contrast-enhanced magnetic resonance imaging (MRI) can classify fibrosis noninvasively, using histology as a reference standard. MATERIALS AND METHODS: A Health Insurance Portability and Accountability Act (HIPAA)-compliant Institutional Review Board (IRB)-approved retrospective study of 68 patients with ...
Farrow Catherine E - - 2012
The regional pattern and extent of airway closure measured by three-dimensional ventilation imaging may relate to airway hyperresponsiveness (AHR) and peripheral airways disease in asthmatic subjects. We hypothesized that asthmatic airways are predisposed to closure during bronchoconstriction in the presence of ventilation heterogeneity and AHR. Fourteen asthmatic subjects (6 women) ...
Amin Reshma - - 2012
Purpose:To determine if fluorine 18 fluorodeoxyglucose (FDG) positron emission tomographic (PET)/computed tomographic (CT) imaging can depict a treatment effect from intravenous antibiotics for pulmonary exacerbation in cystic fibrosis (CF).Materials and Methods:The study was approved by the institutional review board of the Hospital for Sick Children and by Health Canada. Consent ...
Butler James P - - 2012
A 33-year-old woman underwent a right-sided pneumonectomy in 1995 for treatment of a lung adenocarcinoma. As expected, there was an abrupt decrease in her vital capacity, but unexpectedly, it increased during the subsequent 15 years. Serial computed tomographic (CT) scans showed progressive enlargement of the remaining left lung and an ...
Nunes Hilario - - 2012
Imaging has a prominent role in the assessment of sarcoidosis diagnosis and outcome, which are extremely variable. Chest radiography staging helps predict the probability of spontaneous remission, and stage IV is associated with higher mortality. However, the reproducibility of reading is poor and changes in radiography and lung function are ...
Takeuchi Mitsuru - - 2012
We present an adult case of segmental multicystic dysplastic kidney (SMCDK). The patient had a 10 × 6 cm oval-shaped mass consisting of a solid and multilocular cystic component at the right upper renal sinus. The solid component showed gradual and mild enhancement on dual-phase enhanced CT. Excretory-phase CT demonstrated the excretion of ...
Kozinszky Zoltan - - 2012
Sonographic scan revealed a homogenously hyperechogenic lesion in the right fetal lung with microcystic pattern by a primigravid women at 22nd weeks of gestation. A large congenital pulmonary airway malformation (CPAM) was suspected with a lesion-to-lung ratio over 90%. The microcystic image of this thoracic anomaly was moderately visible on ...
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