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Jung Seung Min SM Division of Rheumatology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South - - 2014
A 26-year-old female patient was referred to the clinic with an erythematous, indurated plaque on the right temple. The skin lesion developed at the injection site of a therapeutic intervention for alopecia performed 2 years previously. She complained of symptoms that waxed and waned for several months. Visual inspection suggested ...
Mena Esther E From the *Molecular Imaging Program, and †Biometric Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, MD; ‡Brookhaven National Laboratories, Upton, NY; and §SAIC Contractor to NCI, Fort Detrick Frederick, MD; and ¶Lymphoma Therapeutics Section, Center for Cancer Research, National Cancer Institute, Bethesda, - - 2014
Despite its success in diagnosing and staging lymphoma, F-FDG PET/CT can be falsely positive in areas of posttreatment inflammation. 3'-F-fluoro-3'-deoxy-l-thymidine (F-FLT) is a structural analog of the DNA constituent thymidine; its uptake correlates with cellular proliferation. This pilot study evaluates the ability of F-FLT PET/CT to distinguish viable lymphoma from ...
Zhou Wen-Lan WL aNanFang PET Center, Nanfang Hospital, Southern Medical University bMedical Device School, Guangdong Food and Drug Vocational College, Guangzhou, - - 2014
Neurolymphomatosis (NL) is an uncommon complication of lymphoma and leukemia. Few data have been reported regarding the utilization of fluorine-18 fluorodeoxyglucose PET/computed tomography (F-FDG PET/CT) in this disease. The aim of this study was to assess the role of F-FDG PET/CT in the diagnosis of NL. Eight patients who suffered ...
Xia Z Z Department of Orthopaedic Surgery, Singapore General Hospital, Outram Road, Singapore 169608. - - 2014
Fluorodeoxyglucose (FDG) hepatic superscan refers to the diffuse intense uptake of 18F-FDG in the liver on positron emission tomography (PET), with reduced physiological activity in the brain and heart. The common causes include lymphoma and metastasis. In this case report, we describe the imaging features of tuberculosis as a rare ...
Patil Vivek V VV Department of Radiology, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY, - - 2014
We present a 71-year-old female with human herpes virus 8 (HHV8)-unrelated primary effusion lymphoma (PEL)-like lymphoma. Dyspnea and pericardial effusion led to pericardiocentesis, diagnosing diffuse large B-cell lymphoma. She underwent positron emission tomography/computed tomography (PET/CT), which demonstrated hypermetabolic pericardial, pleural, and ascites fluid without lymphadenopathy elsewhere. Malignant fluid in the ...
Xiao Desheng D Department of Pathology, Xiangya School of Medicine, Central South University Hunan, - - 2014
Intravascular large B-cell lymphoma (IVLBCL) is a rare type of extranodal large B-cell lymphoma characterized by the selective growth of lymphoma cells within the lumina of vessels, particularly within capillaries, with exception of larger arteries and veins. The authors reported a case of a 45-year-old woman who was admitted in ...
Kim Hoe Suk - - 2012
OBJECTIVE: This study aims to produce the transgenic mice (TG) engineered for magnetic resonance imaging (MRI) studies based on the ubiquitous expression of ferritin MRI reporter gene in diverse tissues. PROCEDURES: Transgenic mice (TG) expressing myc-tagged human heavy chain ferritin (myc-hFTH) under the control of a ubiquitous CAG promoter were ...
Maas Monique - - 2012
Magnetic resonance imaging (MRI) is not accurate in discriminating T1-2 from borderline T3 rectal tumors. Higher resolution on 3 Tesla-(3T)-MRI could improve diagnostic performance for T-staging. The aim of this study was to determine whether 3T-MRI compared with 1.5 Tesla-(1.5T)-MRI improves the accuracy for the discrimination between T1-2 and borderline ...
Spiro Stephen G SG The Royal Brompton Hospital, London Hospital, London, UK. - - 2012
While low-dose CT scans have been shown to detect greater numbers of early lung cancers than conventional CXR, the first randomized trial of CT versus CXR screening in more than 50 000 subjects has shown a 20% reduction in mortality with CT. There are several other randomized trials in progress. ...
Codreanu Ion - - 2012
The number of diagnostic positron emission tomography/computed tomography (PET/CT) procedures performed in the USA and worldwide is rapidly increasing. Although the benefits of these procedures are obvious, the increasing use of radiopharmaceuticals requires a better understanding of potential adverse affects and their proper management. We present herein the first report ...
Al-Sukhni Eisar - - 2012
Magnetic resonance imaging (MRI) is increasingly being used for rectal cancer staging. The purpose of this study was to determine the accuracy of phased array MRI for T category (T1-2 vs. T3-4), lymph node metastases, and circumferential resection margin (CRM) involvement in primary rectal cancer. Medline, Embase, and Cochrane databases ...
Patel Payal - - 2012
PURPOSE: To investigate the value of whole-body positron emission tomography/computed tomography (PET/CT) as a screening tool for patients with uveal metastasis. DESIGN: Retrospective observational case series. METHODS: Setting: Clinical practice. Study population: Eighteen patients with uveal metastatic tumors were evaluated. Patients had no history of malignancy or a past medical ...
Lawrence Edward M - - 2012
A significant amount of research has focused on the role of diffusion-weighted MRI (DW-MRI) in the management of patients with prostate cancer. Although uncertainties remain, a clearer picture of where this technique fits into clinical practice is now available. A combination of DW-MRI and T2-weighted MRI (T2W-MRI) demonstrates improved accuracy ...
Ozcan Kara Pelin - - 2012
The differential diagnosis at the inguinal region is very important for hypermetabolic foci because of the possibility of metastasis at this level in cancer patients ongoing PET imaging for detection of metastases. It is important to distinguish this activity from other possible malignant and benign conditions such as lymph node ...
Palma Maurizia Dalla - - 2012
Gynecologic cancers represent a major global healthcare problem since they are associated with a significant mortality and morbidity. Over the last decade, considerable efforts have been spent in the development and optimization of novel diagnostic modalities to achieve an early diagnosis, aid in choosing appropriate treatment, improving long term surveillance, ...
van Kruchten Michel - - 2012
16α-(18)F-fluoro-17β-estradiol ((18)F-FES) is an estrogen receptor (ER)-specific PET tracer with various potential interesting applications. The precise contribution of this technique in current clinical practice, however, has yet to be determined. Therefore, the aim of this study was to evaluate the value of (18)F-FES PET in breast cancer patients presenting with ...
Raja J V - - 2012
The aim of this study was to investigate the usefulness of texture analysis in the characterization of oral cancers involving the buccal mucosa and to assess its effectiveness in differentiating between the various grades of the tumour. Contrast enhanced CT examination was carried out in 21 patients with carcinoma of ...
Xu Yingding Y Molecular Imaging Program at Stanford (MIPS), Department of Radiology and Bio-X Program, Canary Center at Stanford for Cancer Early Detection, Stanford University, Stanford, CA, - - 2012
Cerenkov luminescence imaging (CLI) has emerged as a less expensive, easier-to-use, and higher-throughput alternative to other nuclear imaging modalities such as PET. It is expected that CLI will find many applications in biomedical research such as cancer detection, probe development, drug screening, and therapy monitoring. In this study, we explored ...
Nijkamp Jasper - - 2012
PURPOSE: To quantify the inter-fraction shape variation of the CTV in rectal-cancer patients treated with 5×5 (SCRT) and 25×2Gy (LCRT) and derive PTV margins. METHODS AND MATERIALS: Thirty-three SCRT with daily repeat CT scans and 30 LCRT patients with daily scans during the first week followed by weekly scans were ...
Vandecasteele Katrien - - 2012
OBJECTIVE: To report on the value of magnetic resonance imaging (MRI) and 2-deoxy-2-[18] fluoro-D-glucose positron emission tomography computed tomography (FDG PET-CT) in predicting resectability and pathological response of primary locally advanced cervical cancer after neoadjuvant intensity-modulated arc therapy (IMAT) with or without cisplatin (C). METHODS AND MATERIALS: Twenty-seven patients with ...
Salem Shahenda S - - 2012
BACKGROUND: The increase in tumor markers with negative or equivocal conventional imaging modalities represents a serious dilemma in the follow-up of previously treated cancer patients. Positron emission tomography/computed tomography (PET/CT) has emerged as a useful tool in oncological imaging in staging and restaging of most cancers. OBJECTIVE: This study explored ...
Piccardo Arnoldo - - 2012
PURPOSE: So far, no studies comparing (18)F-Fluoride-PET/CT and MDCT for the detection of bone metastases are available. We compared the accuracy of (18)F-Fluoride-PET/CT (MDCT: 3.75mm thickness-image-reconstruction), whole-body Multi-Detector-CT (MDCT: 1.25mm thickness-image-reconstruction) and (18)F-Fluoride-PET/MDCT (MDCT: 1.25mm thickness-image-reconstruction) in identifying bone metastases in breast cancer patients. METHODS: We studied 39 breast cancer ...
Kreeft Anne Marijn - - 2012
Treatment of oral and oropharyngeal cancer may cause dysphagia. Purpose is to examine whether cine magnetic resonance imaging (MRI) yields additional information compared to standard examination in the evaluation of posttreatment dysphagia and mobility of oral and oropharyngeal structures. Thirty-four cine MRIs were made in 23 patients with advanced oral ...
Bäuerle Tobias - - 2012
Bone is among the most common locations of metastasis and therefore represents an important clinical target for diagnostic follow-up in cancer patients. In the pathogenesis of bone metastases, disseminated tumor cells proliferating in bone interact with the local microenvironment stimulating or inhibiting osteoclast and osteoblast activity. Non-invasive imaging methods monitor ...
Franklin J M - - 2012
AIM: To describe the post-chemoradiotherapy magnetic resonance imaging (MRI) features of locally advanced rectal carcinoma (LARC) in which there has been a complete histopathological response to neoadjuvant chemoradiotherapy (CRT). MATERIALS AND METHODS: This retrospective cohort study was performed between January 2005 and November 2009 at a regional cancer centre. Consecutive ...
Aparici Carina Mari - - 2012
(111)In-capromab pendetide is an imaging probe for noninvasive detection of prostate cancer dissemination, and can be difficult to interpret because of low photon statistics resulting in noisy images with limited anatomical precision. We examined if a 16-slice multidetector computed tomography (MDCT) combined with single photon emission computed tomography (SPECT) could ...
Vargas Hebert Alberto - - 2012
Many management options are available to patients with newly diagnosed prostate cancer. Magnetic resonance (MR) imaging plays an important role in initial staging of prostate cancer, but it also aids in tumor detection when there is clinical or biochemical suspicion of residual or recurrent disease after treatment. The purpose of ...
Beddy Peter - - 2012
Endometrial cancer is the most commonly diagnosed gynecologic malignancy in the United States. This pathologic condition is staged with the International Federation of Gynecology and Obstetrics (FIGO) system. The FIGO staging system recently underwent significant revision, which has important implications for radiologists. Key changes incorporated into the 2009 FIGO staging ...
Park Hye Lim - - 2012
A 51-year-old man was diagnosed with small cell lung cancer (SCLC) with brain, left adrenal gland, and pancreas metastases. On evaluation of treatment response after chemotherapy and radiation therapy, F-18 FDG PET/CT showed focal FDG uptake in the periappendiceal area with thickened appendiceal wall and inflammatory change. Laparoscopic appendectomy was ...
Phang P Terry - - 2012
: At present, pelvic phased array-coil MR is used as the validated imaging modality for measurement of the closest predicted radial mesorectal margin for rectal cancer. Endorectal ultrasound is also used to assess the clinical stage of the cancer that will determine the recommendation for neoadjuvant chemoradiation, but it has ...
Kim Eun Young - - 2012
The objective of the study was to evaluate the computed tomographic (CT) features and growth rates of pulmonary metastases from colorectal cancer (CRC) on serial CT scans. The study included 17 patients (28 pulmonary metastases) who underwent metastasectomy from CRC. The characteristic CT features include well-defined round or oval nodules ...
Aydin Hasan - - 2012
The aim of this study was to optimize and predict the most efficient magnetic resonance imaging (MRI) sequences; T1-weighted (T1W), T2-weighted (T2W), dynamic contrast-enhanced (DCE) T1W, diffusion-weighted imaging (DWI) apparent diffusion coefficient (ADC) mapping sequences and proton MR spectroscopy (H-MRS) for the detection of prostate cancer. After institutional review board ...
Lee Jae-Hoon - - 2012
The purposes of this study were to assess the diagnostic accuracy of (18)F-FDG PET (FDG PET) for the detection of metastatic supraclavicular lymph nodes (LNs) and to propose an optimal diagnostic strategy with additional sonography, contrast-enhanced CT (CECT), or both. One hundred supraclavicular LNs initially detected using FDG PET were ...
Kim Tae Jung - - 2012
The purposes of our study were to evaluate (18)F-FDG PET findings of ground-glass opacity (GGO) nodules and to determine the value of FDG PET for the preoperative staging of lung cancer manifesting predominantly as GGO. Eighty-nine patients (46 men and 43 women; mean [± SD] age, 62.4 ± 7.2 years ...
Yakar Derya - - 2012
Multiparametric magnetic resonance imaging (MRI) has the potential of being the ideal prostate cancer (PCa) assessment tool. Information gathered with multiparametric MRI can serve therapy choice, guidance of interventions, and treatments. The purpose of this review is to discuss the potential role of multiparametric MRI in focal therapy with respect ...
Bradford Brittany R - - 2012
A 29-year-old Caucasian married man, Mr. A, is the father of a 1-year-old daughter and is a successful tax attorney who maintains a healthy lifestyle. While performing a testicular self-examination, Mr. A noticed a small, fixed mass in his left scrotum. After medical workup, biopsy, and consultation, a left orchiectomy ...
Yu Mi Kyung - - 2012
Nanomaterials offer new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions including targeting, imaging, therapy, and etc have been intensively studied aiming to overcome limitations associated with conventional cancer diagnosis and therapy. Of various nanoparticles, magnetic iron oxide nanoparticles with superparamagnetic property have shown potential as multifunctional ...
Trivedi Hari - - 2012
To demonstrate the use of a patient-specific magnetic resonance imaging (MRI)-based prostate mold to generate histologic sections that directly correlate to axial MRI slices in a patient with anteriorly located prostate cancer. Anteriorly located prostate cancer has traditionally been difficult to detect on digital rectal examination and transrectal ultrasound-guided biopsy. ...
Hillner Bruce E BE Department of Internal Medicine and the Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia 23298, USA. - - 2012
In July 2001, PET became a covered service for Medicare beneficiaries when used for the diagnosis, staging, and restaging of non-small-cell lung, esophageal, colorectal, and head and neck cancers as well as lymphoma and melanoma. Whether physicians use PET as a replacement for or in addition to CT, MRI, or ...
Morotti Matteo - - 2011
PURPOSE: To evaluate the available information on the preoperative diagnosis of borderline ovarian tumors (BOTs). METHODS: Articles were identified through electronic databases (Medline and EMBASE, MEDLINE, PubMed), no date or language restrictions were placed; relevant citations were hand searched. RESULTS: Women with BOTs are more likely to have no symptom ...
Wells I T - - 2011
AIM: To evaluate the role of 2-[(18)F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography (PET)/ computed tomography (CT) in the current multidisciplinary management of anal cancer, both in initial staging and in follow-up post-treatment. MATERIALS AND METHODS: All patients referred to the region-wide multidisciplinary meeting for anal cancer during the study period received PET/CT ...
Wijnen Jannie P - - 2011
This study presents quantified levels of phosphorylated metabolites in glandular tissue of human breast using (31) P magnetic resonance spectroscopy at 7 T. We used a homebuilt (1) H/(31) P radiofrequency coil to obtain artifact-free (31) P MR spectra of glandular tissue of healthy females by deploying whole breast free ...
Lin Michael - - 2011
To evaluate FDG PET-CT in the detection of unexpected pre-malignancy or second malignancy at the initial staging of patients with histologically proven non-small cell lung cancer (NSCLC) and its impact on management. METHODS: Staging FDG PET-CT scans acquired between February 2006 and July 2010 in 649 patients (M=389; F=260) with ...
Zhao Lin - - 2011
BACKGROUND: We performed a meta-analysis to evaluate the role of (18)F-fluorodeoxyglucos -e positron emission tomography/computed tomography ((18)FDG-PET/CT) in detecting mediastinal nodal metastasis in patients with non-small cell lung cancer (NSCLC). METHODS: Studies about (18)FDG-PET/CT for detecting mediastinal nodal metastasis in patient with NSCLC were systematically searched in the MEDLINE, EMBASE, ...
Sharma Punit - - 2011
The incidence of thrombosis in patients with underlying primary malignancy is high. The thrombus may be the more common venous thromboembolism (VTE) or the rare tumour thrombus. VTE is a common entity in cancer patients and is managed with anticoagulant therapy, while tumour thrombosis requires aggressive multimodality management. Conventional imaging ...
Singer Lisa L Department of Radiology and Biomedical Imaging, University of California, San Francisco, 1600 Divisadero Street, Box 1667, San Francisco, CA 94115-1667, - - 2012
The aim of this study was to evaluate differences in tumor depiction and measured tumor apparent diffusion coefficient (ADC) with the use of a high-resolution diffusion-weighted (DW) magnetic resonance imaging (MRI) sequence, compared to a standard DW MRI sequence, in patients with locally advanced breast cancer. Patients with locally advanced ...
Mortazavi-Jehanno Nina - - 2011
PURPOSE: The purpose of this pilot study was to assess whether outcome in metastatic or recurrent breast cancer patients is related to metabolic response to endocrine therapy determined by (18)F-FDG PET/CT. METHODS: The study group comprised 22 patients with breast cancer (age 58 ± 11 years, mean ± SD) who were scheduled to receive endocrine ...
de Chickera Sonali - - 2011
The clinical application of dendritic cells (DC) as adjuvants in immunotherapies such as the cell-based cancer vaccine continues to gain interest. The overall efficacy of this emerging immunotherapy, however, remains low. Studies suggest the stage of maturation and activation of ex vivo-prepared DC immediately prior to patient administration is critical ...
Wong W L - - 2011
AIMS: To assess the value of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in patients with squamous cell and undifferentiated cancer neck nodes and no primary site on conventional assessment. MATERIALS AND METHODS: Seventy-eight patients with neck nodal metastases from an unknown primary cancer were studied. PET/CT was carried out ...
Peng Zhongmin - - 2011
BACKGROUND: This study compares the diagnostic abilities of integrated (11)C-choline PET/CT imaging and contrast-enhanced helical CT imaging in pulmonary lesions and locoregional lymph node metastases in patients with lung cancer. PATIENTS AND METHODS: One hundred eight patients with proven or suspected lung cancer underwent integrated (11)C-choline PET/CT and contrast-enhanced CT, ...
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