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Tamene Ashenafi M AM Division of Cardiology, University of Minnesota Medical Center, 420 Delaware Street Southeast MMC 508, Minneapolis, MN 55455, - - 2015
Patients with cancer are subject to short-term and long-term adverse cardiovascular outcomes from cancer therapies. It is important to identify patients at risk for cardiotoxicity so that appropriate therapy can be instituted early. Cardiovascular magnetic resonance (MR) imaging is emerging as a promising imaging modality with unique applications beyond standard ...
Liu Yiyan Y Yiyan Liu, Nuclear Medicine Service, Department of Radiology, New Jersey Medical School, Newark, NJ 07103, United - - 2014
Fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) is not indicated or recommended in the initial staging of early breast cancer. Although it is valuable for detecting distant metastasis, providing prognostic information, identifying recurrence and evaluating response to chemotherapy, the role of FDG PET/CT in evaluating locoregional nodal status for initial ...
Verwer Eline E EE Eline E Verwer, Ronald Boellaard, Department of Radiology and Nuclear Medicine, VU University Medical Center, 1007 MB, Amsterdam, The - - 2014
In lung cancer, tumor hypoxia is a characteristic feature, which is associated with a poor prognosis and resistance to both radiation therapy and chemotherapy. As the development of tumor hypoxia is associated with decreased perfusion, perfusion measurements provide more insight into the relation between hypoxia and perfusion in malignant tumors. ...
Kijima Shigeyoshi S Shigeyoshi Kijima, Takahiro Sasaki, Koichi Nagata, Kenichi Utano, Hideharu Sugimoto, Department of Radiology, Jichi Medical University, Tochigi 329-0498, - - 2014
Imaging studies are a major component in the evaluation of patients for the screening, staging and surveillance of colorectal cancer. This review presents commonly encountered findings in the diagnosis and staging of patients with colorectal cancer using computed tomography (CT) colonography, magnetic resonance imaging (MRI), and positron emission tomography (PET)/CT ...
Hou Wei Shu WS Department of Radiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, No. 160 Pujian Rd., Pudong, Shanghai 200127, PR - - 2014
To investigate the value of dual-energy spectral computed tomography (DESCT) in the quantitative differentiation between pulmonary malignant masses and inflammatory masses. This study was an institutional review board-approved study, and written informed consent was obtained from all patients. Sixty patients with 35 lung cancers and 25 inflammatory masses underwent DESCT ...
Li Liang L Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, - - 2014
To investigate tumor aggressiveness in peripheral zone prostate cancer (PCa) by correlating Gleason score (GS) with diffusion tensor imaging (DTI) from multiparametric magnetic resonance imaging (MRI) at 3.0 Tesla (T). Eighty-three patients with pathological proven peripheral zone PCa whose GS in at least one core biopsy met the criteria(GS ≤3+3, ...
Woolf D K DK Breast Cancer Research Unit, Mount Vernon Cancer Centre, Northwood, - - 2014
Bone is the most common site for breast cancer metastases, occurring in up to 70% of those with metastatic disease. In order to effectively manage these patients it is essential to have consistent, reproducible and validated methods of assessing response to therapy. We present current clinical practice of imaging response ...
Bunting David M DM Peninsula Oesophago-gastric Unit, Derriford Hospital, Plymouth, Devon, PL6 8DH, UK, - - 2014
Positron emission tomography-computed tomography (PET-CT) scanning is used routinely in the staging of oesophageal cancer to identify occult metastases not apparent on CT and changes the management in typically 3-18 % patients. The authors aim to re-evaluate its role in the management of oesophageal cancer, investigating whether it is possible to ...
Bu Wenzhe W Department of Surgical Oncology (Interventional Therapy), Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Jinan, Shandong 250117, P.R. - - 2014
Positron emission tomography (PET) using (18)F-fluorodeoxyglucose has been widely used for analyzing cellular metabolism. The present study aimed to evaluate the association between the diagnostic value of PET/computed tomography (CT) in patients with post-operative recurrent and metastatic colorectal cancer (CRC), and the different levels of carcinoembryonic antigen (CEA). A total ...
Haaga John R JR 1 Department of Radiology, University Hospitals of Cleveland, Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH. - - 2014
OBJECTIVE. Traditional vasculogenesis has many contradictions related to treatment and imaging. This occurs because cancer also uses glycolysis, which does not need oxygen or arteries. Glycolytic lactate supports many procancer processes but high levels of it inhibit glycolysis. CONCLUSION. To avoid this, lactate induces vascular growth factors that initiate glycolytic ...
Wibmer Andreas A 1 Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY - - 2014
OBJECTIVE. The purpose of this study was to evaluate the usefulness and diagnostic performance of a 5-point standardized diagnostic certainty lexicon for reporting the likelihood of extracapsular extension (ECE) of prostate cancer on routine staging prostate MRI. MATERIALS AND METHODS. This study was a retrospective analysis of routine clinical prostate ...
van de Schoot Agustinus J A J AJ Department of Radiation Oncology, Academic Medical Center, University of Amsterdam , Amsterdam , The - - 2014
Background. To safely optimize target volumes using magnetic resonance imaging (MRI) for uterine cervical cancer radiation therapy, MRI findings need to be validated. The aim of this study was to correlate pre-operatively acquired MRI and surgical specimen imaging for uterine cervical cancer patients using deformable image registration and quantify gross ...
Short Ryan G RG Department of Internal Medicine, Kettering Medical Center; Kettering, OH, USA - - - 2014
Leptomeningeal metastasis (LM) is a rare but increasingly common condition in which malignant cells migrate to the meninges. The gold standard for diagnosing LM is detection of cancer cells in the cerebrospinal fluid (CSF). Contrast enhanced-magnetic resonance imaging (CE-MRI) is also used to diagnose LM. We describe a case of ...
Lubina Nóra N Department of Diagnostic and Interventional Radiology, University of Würzburg, Oberdürrbacher Strasse 6, 97080, Würzburg, - - 2014
To compare 3.0 Tesla breast magnetic resonance imaging (MRI) with galactography for detection of benign and malignant causes of nipple discharge in patients with negative mammography and ultrasound. We prospectively evaluated 56 breasts of 50 consecutive patients with nipple discharge who had inconspicuous mammography and ultrasound, using 3.0 Tesla breast ...
Billing Andrea A Department of Urology, Ludwig-Maximilians-University, Marchioninistrasse 15, 81377, Munich, Germany, - - 2014
To evaluate the staging accuracy of preoperative multiparametric MRI (mp-MRI), its influence on the technique of radical retropubic prostatectomy (RRP), and its value for daily clinical practice. A total of 106 patients underwent RRP (January 2011-June 2012) and had preoperative MRI staging data available for review. Staging results acquired by ...
Muijs Christina T CT Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: - - 2014
The aim of this prospective study was to determine the proportion of locoregional recurrences (LRRs) that could have been prevented if radiotherapy treatment planning for oesophageal cancer was based on PET/CT instead of CT. Ninety oesophageal cancer patients, eligible for high dose (neo-adjuvant) (chemo)radiotherapy, were included. All patients underwent a ...
Melsaether Amy A From the School of Medicine, New York University, New York, - - 2014
Dynamic contrast-enhanced breast magnetic resonance imaging (MRI) is a well-established, highly sensitive technique for the detection and evaluation of breast cancer. Optimal performance of breast MRI continues to evolve. This article addresses breast MRI applications, covers emerging breast MRI safety concerns; outlines the technical aspects of breast MRI, including equipment ...
Park Ja Young - - 2014
Biomedical imaging is an essential tool for diagnosis and therapy of diseases such as cancers. It is likely true that medicine has developed with biomedical imaging methods. Sensitivity and resolution of biomedical imaging methods can be improved with imaging agents. Furthermore, it will be ideal if imaging agents could be ...
Panagiotaki Eleftheria E From the *Centre for Medical Image Computing, †Centre for Medical Imaging, ‡Research Department of Urology, Division of Surgery and Interventional Sciences, §Department of Medical Physics and Bioengineering, and ∥Department of Histopathology, University College London Hospitals NHS Foundation Trust (UCLH), University College London, London, United - - 2014
The aim of this study was to demonstrate the feasibility of the recently introduced Vascular, Extracellular, and Restricted Diffusion for Cytometry in Tumours (VERDICT) framework for imaging prostate cancer with diffusion-weighted magnetic resonance imaging (DW-MRI) within a clinical setting. The VERDICT framework is a noninvasive microstructure imaging technique that combines ...
Kim Seung Ho SH Department of Radiology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Republic of Korea - - 2014
Because further treatment plans depends on lymph node (LN) status after neoadjuvant chemoradiation therapy (CRT), the accurate characterization of LN is important. To evaluate the diagnostic performance of apparent diffusion coefficient (ADC) for LN characterization after CRT and to compare the performance with that of LN size. Fifty-three patients (36 ...
Omami Galal G Department of Oral Diagnosis and Polyclinics, Faculty of Dentistry, The Hong Kong University, Hong - - 2014
A combination of positron emission tomography (PET) with (18)F-labeled fluoro-2-deoxyglucose ((18)F-FDG) and computed tomography ((18)F-FDG-PET/CT) has increasingly become a widely used imaging modality for the diagnosis and management of head and neck cancer. On the basis of both recent literature and our professional experience, we present a set of principles ...
Burtnyk Mathieu M Profound Medical Inc., Toronto, Ontario, Canada. Electronic address: - - 2014
To determine the safety and feasibility of MRI-guided transurethral ultrasound prostate ablation using active temperature feedback control in a pre-clinical canine model with 28-day follow-up. Following a long period of acclimatization, ultrasound treatment was performed on eight subjects using the MRI-guided TULSA-PRO developed by Profound Medical Inc. Comprehensive exams and ...
Lee Elaine Yuen Phin EY Department of Diagnostic Radiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong, - - 2014
To investigate the relationship between intravoxel incoherent motion (IVIM) diffusion-weighted magnetic resonance imaging (MRI) and dynamic contrast-enhanced MRI (DCE-MRI) in cervical cancer perfusion. Prospective newly diagnosed cervical cancer patients underwent diffusion-weighted MRI (13 b-values: 1-1000 s/mm(2) ) and DCE-MRI. The IVIM perfusion parameters, perfusion fraction (f), pseudodiffusion coefficient (D*), and ...
Bratan Flavie F From the Departments of Urinary and Vascular Radiology (F.B., O.R.), Pathology (F.M.), and Urology (S.C., M.C., A.G.), Hospices Civils de Lyon, Hôpital Edouard Herriot, 5 place d'Arsonval, 69437 Lyon Cedex 03, France; Université de Lyon, Lyon, France (F.B., S.C., M.C., O.R.); Université Lyon 1, Faculté de Médecine Lyon Est, Lyon, France (F.B., S.C., M.C., O.R.); Inserm, U1032, LabTau, Lyon, France (F.B., R.S., A.H.D., S.C., A.G., O.R.); Laboratoire d'Ecologie Alpine, Université Joseph Fourier, Grenoble, France (C.M.); and CNRS, UMR 5553, Grenoble, France - - 2014
Purpose To assess the factors influencing multiparametric ( MP multiparametric ) magnetic resonance (MR) imaging accuracy in estimating prostate cancer histologic volume ( Vh histologic volume ). Materials and Methods A prospective database of 202 patients who underwent MP multiparametric MR imaging before radical prostatectomy was retrospectively used. Institutional review ...
Viswanath Satish S Case Western Reserve University, NJ, - - 2014
Laser interstitial thermal therapy (LITT) is a new therapeutic strategy being explored in prostate cancer (CaP), which involves focal ablation of organlocalized tumor via an interstitial laser fiber. While little is known about treatment-related changes following LITT, studying post-LITT changes via imaging is extremely significant for enabling early image-guided intervention ...
Rasmussen Jakob F JF The Research Unit for General Practice and Section of General Practice, Department of Public Health, University of Copenhagen, Øster Farimagsgade 5, 1014 Copenhagen K, Denmark. Electronic address: - - 2014
To measure the psychosocial consequences in the Danish lung cancer screening trial (DLCST) and compare those between the computed tomography (CT) group and the control group. This study was a single centre randomised controlled trial with five annual screening rounds. Healthy current or former heavy smokers aged 50-70 years (men ...
Farag Adam A Imaging Research Laboratories, Robarts Research Institute, Western University, London, ON, Canada, N6A - - 2014
To develop and optimize radiofrequency (RF) hardware for the detection of endogenous sodium ((23) Na) by 3.0 Tesla (T) MRI in the human prostate. A transmit-only receive-only (TORO) RF system of resonators consisting of an unshielded, asymmetric, quadrature birdcage (transmit), and an endorectal (ER), linear, surface (receive) coil were developed ...
Kim Min Ju MJ Department of Radiology, Korea University Anam Hospital, Korea University College of Medicine, Seoul, - - 2014
Transrectal ultrasonography (TRUS) has been widely accepted as a popular imaging modality for Epub ahead of print evaluating the lower rectum, anal sphincters, and pelvic floor in patients with various anorectal diseases. It provides excellent visualization of the layers of the rectal wall and of the anatomy of the anal ...
So Young Y Department of Nuclear Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of - - 2014
Skeletal muscle metastasis (SMM) in cancer patients has not been sufficiently evaluated regarding prevalence and proper method of detection. To determine the prevalence of SMM and compare the diagnostic competencies for SMM of torso F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) and contrast-enhanced chest or abdomen CT. We investigated ...
Kusk Martin Weber MW Department of Radiology, Hospital of South West Jutland, Esbjerg, Denmark - - 2014
Generation of multiplanar reformation (MPR) images has become automatic on most modern computed tomography (CT) scanners, potentially increasing the workload of the reporting radiologists. It is not always clear if this increases diagnostic performance in all clinical tasks. To assess detection performance using only coronal multiplanar reformations (MPR) when triaging ...
Gao Xuan X Center of PET/CT, The Third Affiliated Hospital of Harbin Medical University, The Affiliated Tumor Hospital of Harbin Medical University, Harbin, - - 2014
In clinical practice, image analysis is dependent on simply visual perception and the diagnostic efficacy of this analysis pattern is limited for mediastinal lymph nodes in patients with lung cancer. In order to improve diagnostic efficacy, we developed a new computer-based algorithm and tested its diagnostic efficacy. 132 consecutive patients ...
Sakamoto Takashi T Department of Radiology, Saiseikai Kumamoto - - 2014
Sufficient colonic dilation is important when using CT colonography (CTC) for colorectal cancer screening. We investigated the effect of antispasmodic agents and the patient body habitus on the degree of colonic dilation in screening CTC. We assessed the effect of clinical characteristics (age, gender, body mass index [BMI], and the ...
Gong Jiaying J Department of Radiology, The Sixth Affiliated Hospital (The Gastrointestinal & Anal Hospital) of Sun Yat-sen University, Guangzhou, China Department of Nuclear Medicine, The Sixth Affiliated Hospital (The Gastrointestinal & Anal Hospital) of Sun Yat-sen University, Guangzhou, China Department of Oncology, The Sixth Affiliated Hospital (The Gastrointestinal & Anal Hospital) of Sun Yat-sen University, Guangzhou, China and Department of Colorectal Surgery, The Sixth Affiliated Hospital (The Gastrointestinal & Anal Hospital) of Sun Yat-sen University, Guangzhou, - - 2014
The primary aim of this study was to assess the efficacy of whole-body diffusion-weighted imaging (WB-DWI) in detecting tumour recurrence and metastasis of gastrointestinal cancers by comparison with 18F-2-fluoro-2-deoxy-D-glucose positron emission tomography or computed tomography ((18)F-FDG-PET/CT). A secondary aim was to evaluate the change of apparent diffusion coefficient (ADC) value ...
Novikov Sergey Nikolaevich SN Department of Radiation Oncology and Nuclear Medicine, N.N. Petrov Institute Oncology, Leningradskaya 68, St Petersburg, 197758, Russia, - - 2014
To determine diagnostic accuracy of SPECT, CT and SPECT-CT in axillary lymph node (LN) staging in breast cancer (BC). Sixty consecutive patients with primary operable T1-3NxM0 BC were included in this study. All patients underwent SPECT-CT examination on Symbia-T16 scanner which consists of dual-head gamma camera combined with 16 slices ...
Garcia J R JR Unidad PET/TC, CETIR, España. Electronic address: - - 2014
To assess the diagnostic usefulness of (11)C-choline PET/CT vs. multi-parametric MRI in the prostate cancer relapse. A retrospective study of 21 patients with prostate cancer treated initially with surgery (n=12), radiotherapy (n=9). PSA levels were increased (post-surgery: .3-3.6ng/ml; post-radiotherapy: 2.4-8.8ng/ml). In an interval of time of 15 days all patients ...
McLoughlin L C LC Department of Urology, Tallaght Hospital, Dublin 24, Ireland, - - 2014
Planar bone scintigraphy (PBS) is a standard radiological technique to detect skeletal metastases from prostate cancer (PC), the addition of SPECT-CT to PBS improves its diagnostic accuracy. The aim of this study was to assess the additional value of targeted SPECT-CT with PBS in detecting skeletal metastasis form prostate cancer, ...
Schmidt-Hansen Mia M National Collaborating Centre for Cancer, 2nd Floor, Park House, Greyfriars Road, Cardiff, UK, CF10 - - 2014
A major determinant of treatment offered to patients with non-small cell lung cancer (NSCLC) is their intrathoracic (mediastinal) nodal status. If the disease has not spread to the ipsilateral mediastinal nodes, subcarinal (N2) nodes, or both, and the patient is otherwise considered fit for surgery, resection is often the treatment ...
Ylänen Kaisa K Tampere University Hospital, Department of Paediatrics, Tampere, Finland; University of Tampere, Tampere, - - 2014
The role that plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) and cardiac troponins T (cTnT) and I (cTnI) play in supplementing imaging to screen for cardiac late effects remains controversial and the impact of high-sensitivity cTnT and troponin specific autoantibodies (cTnAAbs) remains unexplored. We studied the role of cardiac biomarkers as ...
Pinaquy Jean-Baptiste JB Nuclear Medicine Department, Hôpital Pellegrin, Bordeaux, - - 2014
Accurate staging is important before surgical decision in patients with high-risk prostate cancer (PCa). The purpose of this study was to prospectively compare the diagnostic performance of (18) F-FCholine and MRI with diffusion weighted imaging (DWIMRI) for local and regional lymph node (LN) staging before radical prostatectomy (RP) with extended ...
Zielinski Anna A RWTH University Hospital Aachen, Department of Nuclear Medicine, Pauwelsstraße 30, 52074 Aachen, Germany. - - 2014
The aim of this study is to evaluate the impact of a high resolution (HR) image reconstruction with a voxel size of 2mm in comparison to the most routinely used standard reconstruction with 4mm voxels in patients suffering from prostate cancer having undergone (18)F-methylcholine PET/CT. Phantom studies were performed using ...
Pickhardt Perry J PJ Department of Radiology, University of Wisconsin School of Medicine & Public Health, Madison, Wisconsin, - - 2014
The aim of this review is to provide an update on important recent advances in radiologic colorectal imaging, with emphasis on detection, staging, and surveillance of colorectal neoplasia. Colorectal imaging advances with magnetic resonance (MR), computed tomography colonography (CTC), and positron emission tomography (PET) over the past year or so ...
Chen Jie J Department of Ultrasound in Medicine, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai Institute of Ultrasound in Medicine, Shanghai 200233, P.R. - - 2015
The detection rate of prostate cancer (PCa) using traditional biopsy guided by transrectal ultrasound (TRUS) is not satisfactory. The aim of this study was to determine the utility of 3-Tesla (3-T) magnetic resonance imaging (MRI) prior to TRUS-guided prostate biopsy and to investigate which subgroup of patients had the most ...
Delongchamps Nicolas Barry NB Department of Urology, Cochin hospital, Paris Descartes University. Electronic address: - - 2014
MRI-TRUS fusion targeted prostate biopsies (TB) were suggested to detect significant cancer with more accuracy than systematic biopsies. The aim of this study was to evaluate the pathological characteristics of Mp-MRI-detected and undetected tumor foci on radical prostatectomy (RP) specimens. We selected 125 consecutive patients treated with RP for a ...
Sahebjavaher Ramin S RS University of British Columbia, Electrical and Computer Engineering, Vancouver, BC, - - 2014
The purpose of this work was (1) to develop a magnetic resonance elastography (MRE) system for imaging of the ex vivo human prostate and (2) to assess the diagnostic power of mono-frequency and multi-frequency MRE and diffusion weighted imaging (DWI) alone and combined as correlated with histopathology in a patient ...
Li Jingchao J State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai 201620, PR China; College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, PR - - 2015
Development of multifunctional theranostic nanoplatforms for diagnosis and therapy of cancer still remains a great challenge. In this work, we report the use of hyaluronic acid-modified Fe3O4@Au core/shell nanostars (Fe3O4@Au-HA NSs) for tri-mode magnetic resonance (MR), computed tomography (CT), and thermal imaging and photothermal therapy of tumors. In our approach, ...
Völker Michael M Research Center for Magnetic Resonance Bavaria, Würzburg, Germany, - - 2014
To optimize a radial turbo spin-echo sequence for motion-robust morphological lung magnetic resonance imaging (MRI) in free respiration. A versatile multi-shot radial turbo spin-echo (rTSE) sequence is presented, using a modified golden ratio-based reordering designed to prevent coherent streaking due to data inconsistencies from physiological motion and the decaying signal. ...
Lee Leslie K LK Leslie K Lee, Dushyant V Sahani, Division of Abdominal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, United - - 2014
Current understanding of autoimmune pancreatitis (AIP) recognizes a histopathological subtype of the disease to fall within the spectrum of IgG4-related disease. Along with clinical, laboratory, and histopathological data, imaging plays an important role in the diagnosis and management of AIP, and more broadly, within the spectrum of IgG4-related disease. In ...
Karantanis Dimitrios D Ahmanson Translational Imaging Division, Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California Department of Nuclear Medicine, Greek Air Force Hospital, Athens, Greece - - 2014
Because only pathologic examination can confirm the presence or absence of malignant disease in cancer patients, a certain rate of misinterpretation in any kind of imaging study is inevitable. For the accuracy of interpretation to be improved, determination of the nature, causes, and magnitude of this problem is needed. This ...
Chen Cheng C Respiratory Department, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, P.R. - - 2015
Recurrent lung cancer is a common clinical condition. (18)F-fluorodeoxyglucose positron emission tomography (FDG-PET) is currently the predominant non-invasive imaging technique used for the detection of tumor recurrence. In the present study, the case of a 67-year-old male suspected to have postoperative recurrence of primary lung cancer was examined. Chest computed ...
Kousaka Junko J Division of Breast and Endocrine Surgery, Department of Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, - - 2014
With increasing use of computed tomography (CT), incidentally detected breast lesions are being encountered more frequently. The aim of our study was to verify the utility of targeted sonography using an image fusion technique, real-time virtual sonography (RVS) that coordinates real-time sonography images with previously obtained CT images using a ...
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