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Bu Wenzhe W Department of Surgical Oncology (Interventional Therapy), Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Jinan, Shandong 250117, P.R. - - 2014
Positron emission tomography (PET) using (18)F-fluorodeoxyglucose has been widely used for analyzing cellular metabolism. The present study aimed to evaluate the association between the diagnostic value of PET/computed tomography (CT) in patients with post-operative recurrent and metastatic colorectal cancer (CRC), and the different levels of carcinoembryonic antigen (CEA). A total ...
Haaga John R JR 1 Department of Radiology, University Hospitals of Cleveland, Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH. - - 2014
OBJECTIVE. Traditional vasculogenesis has many contradictions related to treatment and imaging. This occurs because cancer also uses glycolysis, which does not need oxygen or arteries. Glycolytic lactate supports many procancer processes but high levels of it inhibit glycolysis. CONCLUSION. To avoid this, lactate induces vascular growth factors that initiate glycolytic ...
Wibmer Andreas A 1 Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY - - 2014
OBJECTIVE. The purpose of this study was to evaluate the usefulness and diagnostic performance of a 5-point standardized diagnostic certainty lexicon for reporting the likelihood of extracapsular extension (ECE) of prostate cancer on routine staging prostate MRI. MATERIALS AND METHODS. This study was a retrospective analysis of routine clinical prostate ...
Lee Elaine Yuen Phin EY Department of Diagnostic Radiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong, - - 2014
To investigate the relationship between intravoxel incoherent motion (IVIM) diffusion-weighted magnetic resonance imaging (MRI) and dynamic contrast-enhanced MRI (DCE-MRI) in cervical cancer perfusion. Prospective newly diagnosed cervical cancer patients underwent diffusion-weighted MRI (13 b-values: 1-1000 s/mm(2) ) and DCE-MRI. The IVIM perfusion parameters, perfusion fraction (f), pseudodiffusion coefficient (D*), and ...
Viswanath Satish S Case Western Reserve University, NJ, - - 2014
Laser interstitial thermal therapy (LITT) is a new therapeutic strategy being explored in prostate cancer (CaP), which involves focal ablation of organlocalized tumor via an interstitial laser fiber. While little is known about treatment-related changes following LITT, studying post-LITT changes via imaging is extremely significant for enabling early image-guided intervention ...
Farag Adam A Imaging Research Laboratories, Robarts Research Institute, Western University, London, ON, Canada, N6A - - 2014
To develop and optimize radiofrequency (RF) hardware for the detection of endogenous sodium ((23) Na) by 3.0 Tesla (T) MRI in the human prostate. A transmit-only receive-only (TORO) RF system of resonators consisting of an unshielded, asymmetric, quadrature birdcage (transmit), and an endorectal (ER), linear, surface (receive) coil were developed ...
So Young Y Department of Nuclear Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of - - 2014
Skeletal muscle metastasis (SMM) in cancer patients has not been sufficiently evaluated regarding prevalence and proper method of detection. To determine the prevalence of SMM and compare the diagnostic competencies for SMM of torso F-18 fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) and contrast-enhanced chest or abdomen CT. We investigated ...
Kusk Martin Weber MW Department of Radiology, Hospital of South West Jutland, Esbjerg, Denmark - - 2014
Generation of multiplanar reformation (MPR) images has become automatic on most modern computed tomography (CT) scanners, potentially increasing the workload of the reporting radiologists. It is not always clear if this increases diagnostic performance in all clinical tasks. To assess detection performance using only coronal multiplanar reformations (MPR) when triaging ...
Sakamoto Takashi T Department of Radiology, Saiseikai Kumamoto - - 2014
Sufficient colonic dilation is important when using CT colonography (CTC) for colorectal cancer screening. We investigated the effect of antispasmodic agents and the patient body habitus on the degree of colonic dilation in screening CTC. We assessed the effect of clinical characteristics (age, gender, body mass index [BMI], and the ...
Gong Jiaying J Department of Radiology, The Sixth Affiliated Hospital (The Gastrointestinal & Anal Hospital) of Sun Yat-sen University, Guangzhou, China Department of Nuclear Medicine, The Sixth Affiliated Hospital (The Gastrointestinal & Anal Hospital) of Sun Yat-sen University, Guangzhou, China Department of Oncology, The Sixth Affiliated Hospital (The Gastrointestinal & Anal Hospital) of Sun Yat-sen University, Guangzhou, China and Department of Colorectal Surgery, The Sixth Affiliated Hospital (The Gastrointestinal & Anal Hospital) of Sun Yat-sen University, Guangzhou, - - 2014
The primary aim of this study was to assess the efficacy of whole-body diffusion-weighted imaging (WB-DWI) in detecting tumour recurrence and metastasis of gastrointestinal cancers by comparison with 18F-2-fluoro-2-deoxy-D-glucose positron emission tomography or computed tomography ((18)F-FDG-PET/CT). A secondary aim was to evaluate the change of apparent diffusion coefficient (ADC) value ...
Novikov Sergey Nikolaevich SN Department of Radiation Oncology and Nuclear Medicine, N.N. Petrov Institute Oncology, Leningradskaya 68, St Petersburg, 197758, Russia, - - 2014
To determine diagnostic accuracy of SPECT, CT and SPECT-CT in axillary lymph node (LN) staging in breast cancer (BC). Sixty consecutive patients with primary operable T1-3NxM0 BC were included in this study. All patients underwent SPECT-CT examination on Symbia-T16 scanner which consists of dual-head gamma camera combined with 16 slices ...
McLoughlin L C LC Department of Urology, Tallaght Hospital, Dublin 24, Ireland, - - 2014
Planar bone scintigraphy (PBS) is a standard radiological technique to detect skeletal metastases from prostate cancer (PC), the addition of SPECT-CT to PBS improves its diagnostic accuracy. The aim of this study was to assess the additional value of targeted SPECT-CT with PBS in detecting skeletal metastasis form prostate cancer, ...
Schmidt-Hansen Mia M National Collaborating Centre for Cancer, 2nd Floor, Park House, Greyfriars Road, Cardiff, UK, CF10 - - 2014
A major determinant of treatment offered to patients with non-small cell lung cancer (NSCLC) is their intrathoracic (mediastinal) nodal status. If the disease has not spread to the ipsilateral mediastinal nodes, subcarinal (N2) nodes, or both, and the patient is otherwise considered fit for surgery, resection is often the treatment ...
Ylänen Kaisa K Tampere University Hospital, Department of Paediatrics, Tampere, Finland; University of Tampere, Tampere, - - 2014
The role that plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) and cardiac troponins T (cTnT) and I (cTnI) play in supplementing imaging to screen for cardiac late effects remains controversial and the impact of high-sensitivity cTnT and troponin specific autoantibodies (cTnAAbs) remains unexplored. We studied the role of cardiac biomarkers as ...
Pinaquy Jean-Baptiste JB Nuclear Medicine Department, Hôpital Pellegrin, Bordeaux, - - 2014
Accurate staging is important before surgical decision in patients with high-risk prostate cancer (PCa). The purpose of this study was to prospectively compare the diagnostic performance of (18) F-FCholine and MRI with diffusion weighted imaging (DWIMRI) for local and regional lymph node (LN) staging before radical prostatectomy (RP) with extended ...
Zielinski Anna A RWTH University Hospital Aachen, Department of Nuclear Medicine, Pauwelsstraße 30, 52074 Aachen, Germany. - - 2014
The aim of this study is to evaluate the impact of a high resolution (HR) image reconstruction with a voxel size of 2mm in comparison to the most routinely used standard reconstruction with 4mm voxels in patients suffering from prostate cancer having undergone (18)F-methylcholine PET/CT. Phantom studies were performed using ...
Pickhardt Perry J PJ Department of Radiology, University of Wisconsin School of Medicine & Public Health, Madison, Wisconsin, - - 2014
The aim of this review is to provide an update on important recent advances in radiologic colorectal imaging, with emphasis on detection, staging, and surveillance of colorectal neoplasia. Colorectal imaging advances with magnetic resonance (MR), computed tomography colonography (CTC), and positron emission tomography (PET) over the past year or so ...
Sahebjavaher Ramin S RS University of British Columbia, Electrical and Computer Engineering, Vancouver, BC, - - 2014
The purpose of this work was (1) to develop a magnetic resonance elastography (MRE) system for imaging of the ex vivo human prostate and (2) to assess the diagnostic power of mono-frequency and multi-frequency MRE and diffusion weighted imaging (DWI) alone and combined as correlated with histopathology in a patient ...
Völker Michael M Research Center for Magnetic Resonance Bavaria, Würzburg, Germany, - - 2014
To optimize a radial turbo spin-echo sequence for motion-robust morphological lung magnetic resonance imaging (MRI) in free respiration. A versatile multi-shot radial turbo spin-echo (rTSE) sequence is presented, using a modified golden ratio-based reordering designed to prevent coherent streaking due to data inconsistencies from physiological motion and the decaying signal. ...
Lee Leslie K LK Leslie K Lee, Dushyant V Sahani, Division of Abdominal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, United - - 2014
Current understanding of autoimmune pancreatitis (AIP) recognizes a histopathological subtype of the disease to fall within the spectrum of IgG4-related disease. Along with clinical, laboratory, and histopathological data, imaging plays an important role in the diagnosis and management of AIP, and more broadly, within the spectrum of IgG4-related disease. In ...
Kousaka Junko J Division of Breast and Endocrine Surgery, Department of Surgery, Aichi Medical University, 1-1 Yazakokarimata, Nagakute, Aichi, 480-1195, - - 2014
With increasing use of computed tomography (CT), incidentally detected breast lesions are being encountered more frequently. The aim of our study was to verify the utility of targeted sonography using an image fusion technique, real-time virtual sonography (RVS) that coordinates real-time sonography images with previously obtained CT images using a ...
Bansal Gaurav J GJ The Breast Centre, University Hospital of Llandough, Penarth. UK, CF64 - - 2014
Objectives: a} To compare radiologists' breast mammographic density readings with Computed tomography (CT) subjective measures. b} To correlate computer derived measurement of CT density with subjective assessments. c} To evaluate density distributions in this cohort of patients with breast cancer. Method: Retrospective review of mammograms and CT scans in 77 ...
Khorsandi Azita S AS Department of Radiology, Mount Sinai Beth Israel; New York, NY, - - 2014
Objectives: To study the MRI and PET/CT imaging of osteoradionecrosis of the sub-axial cervical spine, a serious long-term complication of radiation therapy for head and neck cancers that can lead to pain, vertebral instability, myelopathy, and cord compression. Methods and Materials: This is a single-institution retrospective review of patients diagnosed ...
Park Byung Kwan BK The Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
To retrospectively compare re-biopsy with preceded magnetic resonance imaging (MRI) and re-biopsy without preceded MRI. Between January 2007 and May 2011, 669 patients (mean 64 years; range 38-91 years) underwent a re-biopsy because of previous negative biopsy (median 1; 1-5) and persistently high prostate-specific antigen (PSA 10.6 ng/ml; 2.5-997.1 ng/ml). 3T MRI using a ...
Kim Hyun Su HS Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, - - 2014
Positron emission tomography / computed tomography (PET/CT), with its metabolic data of (18) F-fluorodeoxyglucose (FDG) cellular uptake in addition to morphologic CT data, is an established technique for staging of lung cancer and has higher sensitivity and accuracy for lung nodule characterization than conventional approaches. Its strength extends outside the ...
Wang Yinghui Y State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry (CIAC), Chinese Academy of Sciences (CAS), Changchun, 130022 (P. R. - - 2014
Limited therapeutic efficiency and severe side effects in patients are two major issues existing in current chemotherapy of cancers in clinic. To design a proper theranostic platform seems thus quite needed to target cancer cells accurately by bioimaging and simultaneously release drugs on demand without premature leakage. A novel ZnO-functionalized ...
Sun Yang - - 2014
Superparamagnetic poly (lactic-co-glycolic acid) (PLGA)-coated Fe3O4 microcapsules are receiving increased attention as potential diagnostic and therapeutic modalities in the field of oncology. In this study, PLGA-coated Fe3O4 microcapsules were combined with a magnetic resonance imaging-guided high-intensity focused ultrasound (MR-guided HIFU) platform, with the objective of investigating the effects of these ...
Chung Julius J From the *Samsung Advanced Institute of Health Sciences and Technology, †Department of Radiology and the Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, and ‡Department of Radiology, Seoul Veterans Hospital, Seoul, - - 2014
The aim of this study was to validate a semiautomatic detection method for the arterial input functions (AIFs) using Kendall coefficient of concordance (KCC) for quantitative analysis of dynamic contrast-enhanced magnetic resonance imaging in non-small cell lung cancer patients. We prospectively enrolled 28 patients (17 men, 11 women; mean age, ...
Agarwal Ankit A 1 Boston University School of Medicine, Boston, - - 2014
OBJECTIVE. CT remains the imaging modality of choice in the diagnosis of colorectal cancer (CRC) and anal cancer. However, advances in imaging have expanded the role of MRI and PET/CT. This article focuses on the evolving role of FDG PET/CT in the diagnosis, radiation therapy planning, therapy assessment, and posttherapy ...
Rubin Geoffrey D GD From the Duke Clinical Research Institute and Department of Radiology, Duke University School of Medicine, PO Box 17969, 2400 Pratt St, Durham, NC - - 2014
Computed tomography (CT) has had a profound effect on the practice of medicine. Both the spectrum of clinical applications and the role that CT has played in enhancing the depth of our understanding of disease have been profound. Although almost 90 000 articles on CT have been published in peer-reviewed ...
Moszkowicz David D Department of Surgery, Assistance-Publique-Ho^pitaux de Paris, Hôpital Ambroise Paré, Boulogne, - - 2014
Rectal preservation has been proposed as an alternative to radical resection in patients with presumed complete or major response to chemoradiotherapy (CRT). The aim of this prospective study was to evaluate the accuracy of digital rectal examination (DRE) and magnetic resonance imaging (MRI) to predict major or complete rectal cancer ...
Maeda Yoshiaki Y Department of Gastrointestinal Surgery, Hokkaido Cancer Center, Sapporo, - - 2014
We herein report a case of laparoscopic high anterior resection with D3 lymph node dissection for rectosigmoid colon cancer with a horseshoe kidney. A 65-year-old Japanese man referred to our hospital for rectosigmoid colon cancer was found to have a horseshoe kidney on a CT scan. On 3-D CT angiography, ...
Musto Alessandra A Nuclear Medicine Service, Ospedale Maggiore, Bologna, - - 2014
In the present review we reported the value of 18F-fluorodeoxyglucose (FDG) PET/CT in face of uterine cancer, in terms of sensitivity, specificity and accuracy. Moreover, we made a comparison with the other imaging techniques currently used to evacuate these tumors including contrast-enhanced CT, contrast enhanced-MRI and transvaginal ultrasonography. FDG PET/CT ...
Yang Xiaofeng X Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia - - 2014
The technological advances in real-time ultrasound image guidance for high-dose-rate (HDR) prostate brachytherapy have placed this treatment modality at the forefront of innovation in cancer radiotherapy. Prostate HDR treatment often involves placing the HDR catheters (needles) into the prostate gland under the transrectal ultrasound (TRUS) guidance, then generating a radiation ...
Overduin Christiaan G CG Department of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen 6525GA, The - - 2014
To correlate T1-weighted (T1w) magnetic resonance (MR) image contrast around a cryoablation iceball with temperature in a phantom study and to compare this to its in vivo appearance during MR-guided focal cryoablation of prostate cancer. A MR-compatible cryoneedle was inserted into identical gel phantoms (n = 3) on a 1.5 ...
Schmitt Alain A Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, - - 2014
Transurethral MR-HIFU is a minimally invasive image-guided treatment for localized prostate cancer that enables precise targeting of tissue within the gland. The treatment is performed within a clinical MRI to obtain real-time MR thermometry used as an active feedback to control the spatial heating pattern in the prostate and to ...
Crush Andrew Bryce AB From the Departments of Radiology (A.B.C., B.M.H., R.J.S., K.K.A., C.H.H., G.B.J., R.C.M., R.F.M., P.J.P.) and Immunology (G.B.J.), Mayo Clinic, Mayo Building E2, 200 First St SW, Rochester, MN - - 2014
The clinical and imaging evaluation of peripheral neuropathies in patients with cancer is challenging. It is critically important to differentiate malignant invasion of the peripheral nervous system from nonmalignant causes, such as radiation-induced neuritis, neuropathy associated with chemotherapy, and inflammatory neuropathies. Contrast material-enhanced magnetic resonance (MR) imaging is the initial ...
Tirumani Sree Harsha SH From the Departments of Imaging (S.H.T., K.W.K., M.N., S.A.H., K.M.K., J.P.J., N.H.R., A.B.S.) and Medical Oncology (J.M.C.), Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Ave, Boston, MA 02215; and Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (S.H.T., K.W.K., M.N., S.A.H., K.M.K., J.P.J., N.H.R., - - 2014
Evolution in the treatment of metastatic colorectal cancer (mCRC) has led to significant improvement in the survival of these patients. Surgery is useful in patients with resectable disease. Liver-directed therapies such as hepatic arterial infusion, transarterial radio- and chemoembolization, and percutaneous ablation are sometimes used by oncologists when the liver ...
Bitencourt Almir G V AG Department of Imaging (AGVB, ENPL, RC, EFM, JAS, MDG); and Department of Mastology (WPA), A.C. Camargo Cancer Center, São Paulo, SP, - - 2014
The purpose of this study was to evaluate the diagnostic accuracy of multiparametric evaluation of breast lesions combining information of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), diffusion-weighted imaging (DWI), and F-fluoro-deoxi-glucose (F-FDG) positron emission tomography/computed tomography (PET-CT). After approval of the institutional research ethics committee, 31 patients with suspicious breast ...
Miwa Kenta K Department of Diagnostic Radiology Center, Cancer Institute Hospital of Japanese Foundation for Cancer - - 2014
The present study aimed at determining the quantitative accuracy of phase-based respiratory-gated PET/CT imaging using phantom and clinical studies. The effects of target size, target-to-background ratio (TBR), and respiratory motion on PET images were estimated using a NEMA body phantom comprising six spheres (diameter 10-37mm) in a solution of F-18 ...
Kim Arum A Department of Rehabilitation Medicine, New York Presbyterian Hospital, University Hospital of Columbia and Cornell, HP1-167 180 Ft. Washington Ave., New York, NY, - - 2014
Introduction: Lymphedema has long been considered a risk factor for median nerve compression at the wrist and carpal tunnel syndrome (CTS). This association is based on limited and poor quality data. This study analyzed the association between lymphedema and CTS. Methods: Breast cancer survivors with upper extremity lymphedema and electrophysiologically ...
Li Xia X From the *Institute of Imaging Science, †Department of Radiology and Radiological Sciences, ‡the Vanderbilt-Ingram Cancer Center, Departments of §Biostatistics, ∥Radiation Oncology, ¶Medical Oncology, #Surgical Oncology, **Pathology, ††Physics and Astronomy, ‡‡Cancer Biology, and §§Biomedical Engineering, Vanderbilt University, Nashville, - - 2014
The purpose of this study was to determine whether multiparametric magnetic resonance imaging (MRI) using dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted MRI (DWI), obtained before and after the first cycle of neoadjuvant chemotherapy (NAC), is superior to single-parameter measurements for predicting pathologic complete response (pCR) in patients with breast cancer. ...
Nakajima Isao I Department of Radiology, Gunma Central Hospital, 1-7-13 Kouun, Maebashi, Gunma 371-0025 - - 2014
Objective: To identify CT findings of massive venous invasion (MVI) in colorectal cancer, compare them to pathological findings, and evaluate its clinical implications. Methods: Among 423 patients who received surgical resection of colorectal cancer, preoperative CT of 26 patients (15 men, 11 women; 63.0±12.1 years) with histopathologially proved MVI and ...
Altini Corinna C Nuclear Medicine Unit, D.I.M., University of Bari "Aldo Moro", Bari, - - 2014
The aim of this study was to prospectively investigate the predictive value of (18)F-FDG PET/CT semiquantitative parameters for locally advanced low rectal cancer (LARC) treated by neoadjuvant chemoradiation therapy (nCRT). 68 patients with LARC had (18)F-FDG PET/CT scans twice (baseline and 5-6 weeks post-nCRT). All patients underwent surgery with preservation of ...
Ma Chao C Department of Radiology, Changhai Hospital of Shanghai, the Second Military Medical University, Shanghai, PR - - 2014
Proton magnetic resonance spectroscopic imaging (MRSI) of the prostate has been used with only a combination of external surface coils. The quality of spectral fitting of the (choline + creatine)/citrate ([Cho + Cr]/Cit) ratio at different field strengths and different coils is important for quantitative/semi-quantitative diagnosis of prostate cancer. To evaluate the quality of ...
Boda-Heggemann Judit J Department of Radiation Oncology, University Medical Centre Mannheim, University of Heidelberg, Mannheim, Germany. Electronic address: - - 2014
Target-volume definition for prostate cancer in patients with bilateral metal total hip replacements (THRs) is a challenge because of metal artifacts in the planning computed tomography (CT) scans. Magnetic resonance imaging (MRI) can be used for matching and prostate delineation; however, at a spatial and temporal distance from the planning ...
Ivanov V K VK Federal State Institution Medical Radiological Research Centre of the Russian Ministry of Health, 4 Korolyov Street, Obninsk, Kaluga region, 249036, - - 2014
Multiple CT scans are often done on the same patient resulting in an increased risk of cancer. Prior publications have estimated risks on a population basis and often using an effective dose. Simply adding up the risks from single scans does not correctly account for the survival function. A methodology ...
Vallabhajosula Shankar S New York Presbyterian Hospital and Weill Cornell Medical College, New York, New York - - 2014
Prostate-specific membrane antigen (PSMA) is a well-established target for developing radiopharmaceuticals for imaging and therapy of prostate cancer (PCa). We have recently reported that novel (99m)Tc-labeled small-molecule PSMA inhibitors bind with high affinity to PSMA-positive tumor cells in vitro and localize in PCa xenografts. This study reports the first, to ...
Zein Rami K RK Department of Diagnostic Radiology and Molecular Imaging, William Beaumont School of Medicine and Health System, Oakland University, Royal Oak, - - 2014
Diffuse (99m)Tc-sestimibi uptake in the lungs is a sign of serious pathology and merits further work-up. We present a case in which diffuse lung uptake was incidentally found on a parathyroid scan.
Itatani Ryo R From the *Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University; Departments of †Radiology, ‡Urology, and §Pathology, Kumamoto Chuo Hospital; and ∥Department of Diagnostic Radiology, Amakusa Medical Center, Kumamoto, - - 2014
The objective of this study was to assess whether adding isovoxel 3-dimensional T2-weighted imaging (volume isotropic T2-weighted acquisition [VISTA]) to multiparametric magnetic resonance imaging (mp-MRI) improves the ability to diagnose the extracapsular extension (ECE) of prostate cancer. Two radiologists independently evaluated ECE on images acquired with mp-MRI only (method A) ...
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