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Riederer I I From the Departments of Diagnostic and Interventional Neuroradiology (I.R., C.P., J.S.B., J.F.K., C.Z.) and Diagnostic and Interventional Radiology (D.C.K., M.S.), Neuroimaging Center at the Technische Universität München (C.P., M.M.), and Department of Neurology (M.M.), Klinikum rechts der Isar, Technische Universität München, Munich, Germany. - - 2014
MR imaging plays an important role in diagnosing MS and other related inflammatory diseases; however, imaging of the spinal cord is still challenging. We hypothesized that a 3D double inversion recovery sequence for cervical spinal cord imaging would be more sensitive in detecting inflammatory lesions than a conventional 2D T2-weighted ...
Hodel Jérôme J Department of Neuroradiology, Hôpital Roger Salengro, Rue Emile Laine, 59037, Lille, France, - - 2014
We compared the three-dimensional (3D) double inversion recovery (DIR) magnetic resonance imaging (MRI) sequence with the coronal two-dimensional (2D) short tau inversion recovery (STIR) fluid-attenuated inversion recovery (FLAIR) for the detection of optic nerve signal abnormality in patients with optic neuritis (ON). The study group consisted of 31 patients with ...
Shimizu Hironori H Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine.. Electronic address: - - 2014
To compare and evaluate images of non-contrast enhanced MR portography and hepatic venography acquired with two different fat suppression methods, the chemical shift selective (CHESS) method and short tau inversion recovery (STIR) method. Twenty-two healthy volunteers were examined using respiratory-triggered three-dimensional (3D) true steady-state free-precession (SSFP) with two time-spatial labeling ...
Gulko Edwin E Department of Radiology, Montefiore Medical Center, 111 East 210th Street, Bronx, NY, 10467-2401, USA, - - 2014
In modern times scurvy is a rarely encountered disease caused by ascorbic acid (vitamin C) deficiency. However, sporadic cases of scurvy persist, particularly within the pediatric population. Recent individual case reports highlight an increased incidence of scurvy among patients with autism or developmental delay, with isolated case reports detailing the ...
Michos Erin D ED Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland2Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, - - 2014
IMPORTANCE Vitamin D deficiency has been associated with hypertension, diabetes mellitus, and incident stroke. Little is known about the association between vitamin D and subclinical cerebrovascular disease. OBJECTIVE To examine the relationship of 25-hydroxyvitamin D (25[OH]D) levels with cerebrovascular abnormalities as assessed on brain magnetic resonance imaging (MRI) among participants ...
Jain Krishan K KK Department of Radiodiagnosis, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, UP, - - 2014
Subacute combined degeneration (SACD) of the spinal cord, characterized by degeneration of lateral and posterior columns, is often found in vitamin B12 deficiency. Our aim was to look for sensitivity of imaging in depicting the spinal cord abnormality in vitamin B12 deficient patients and to find any correlation of vitamin ...
Iizuka Y Y Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, - - 2014
Objectives:The purpose of this study was to clarify the prognostic factors for cervical spondylotic amyotrophy (CSA).Methods:The authors retrospectively reviewed the medical records of 47 consecutive patients with CSA in whom the presence/absence of the pyramidal tract sign was noted. We analyzed whether the age, sex, presence of diabetes mellitus, medication ...
Saboul Cécile C 1Department of Pediatrics, CHU Saint-Etienne, Saint-Etienne, - - 2014
Cerebral sinovenous thrombosis is unusual during childhood and requires early and accurate management because of its detrimental consequences. We report on the case of a 2-year-old boy with mild psychomotor delay, who presented with nonfebrile acute ataxia. A brain computed tomographic (CT) scan showed complete thrombosis of the superior sagittal ...
Sun Hye Young HY Department of Radiology, Seoul National University Bundang Hospital, 300 Gumidong, Bundag-Gu, Seong Nam, Gyeongi-Do, 463-707, - - 2014
Subacute combined degeneration (SCD) is a potentially reversible neurological complication of a vitamin B12 deficiency; therefore, timely diagnosis and appropriate treatment are of great importance. The study was to evaluate the spine MR imaging features of SCD in a series of patients. Eight patients diagnosed with SCD from 2008 to ...
Rodrigues Napoleão Ramalho NR From the Divisions of *Nuclear Medicine, and †Rheumatology of the Sirio-Libanes Hospital, São Paulo; Departments of ‡Orthopedic Surgery, and §Pathology, Campinas University, - - 2014
A 32-year-old woman presented with progressive myalgia, bone pain, fatigue, insufficiency hip fractures, high urine phosphate, and low serum phosphate and vitamin D levels. These findings were suggestive of oncogenic osteomalacia. A whole-body Tc-octreotide scintigraphy with SPECT/CT showed uptake on a sclerotic intramedullary lesion in the left medial tibia plateau. ...
Schlosser Rodney J RJ Department of Surgery, Ralph H. Johnson VA Medical Center, Charleston, SC; Division of Rhinology & Sinus Surgery, Department of Otolaryngology, Medical University of South Carolina, Charleston, - - 2014
The objective of this work was to determine if specific chronic rhinosinusitis with nasal polyps (CRSwNP) populations are at risk for vitamin D3 (VD3 ) deficiency and if VD3 levels correlate with radiographic measures of disease severity or eosinophilia. This study was a retrospective review of an academic rhinology practice. ...
Román Gustavo C GC Department of Neurology, Weill Cornell Medical College, Methodist Neurological Institute, Houston, TX, USA. Electronic address: - - 2014
A large number of causal agents produce spinal cord lesions in the tropics. Most etiologies found in temperate regions also occur in the tropics including trauma, herniated discs, tumors, epidural abscess, and congenital malformations. However, infectious and nutritional disorders occur with higher prevalence in tropical regions. Among the most common ...
Gratton Sean M SM Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL, - - 2014
Visual loss due to optic neuropathy is a rare manifestation of thiamine deficiency. We report a case of a 39-year-old woman with a body mass index (BMI) of 29 kg/m(2) who developed visual loss and bilateral optic nerve head swelling after a short, self-limited gastrointestinal illness. She was disoriented and ...
Chakrabarty Biswaroop B 1Child Neurology Division, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, - - 2013
Deficiency of vitamin B12 causes megaloblastic anemia and nervous system demyelination. Structures affected in the nervous system include spinal cord, cranial and peripheral nerves, and brain white matter. A 9-year-old boy presented with knuckle hyperpigmentation and oral ulcers for 3 years, pallor and easy fatigability for 6 months, gait abnormalities ...
Gupta P K - - 2013
BACKGROUND AND PURPOSE:Vitamin B12 deficiency may cause neural injury that results in cognitive deficits. The main purpose of our study was to evaluate morphometric and microstructural changes in the brain and relate them to cognition in subacute combined degeneration of the spinal cord and patients with biochemically deficient vitamin B12.MATERIALS ...
Xu Yao - - 2013
Although it has been observed that a vitamin B12 (VB12) deficiency may lead to defects in the nervous system, there is a lack of studies elucidating whether VB12 has a role in the pathogenesis of cervical spondylotic myelopathy (CSM). The present study describes two cases of CSM observed in the ...
Berg Isaac - - 2013
Vitamin D and vitamin D binding protein (DBP) have been associated with COPD and FEV1. There are limited data regarding emphysema and vitamin D and DBP. This is a pilot study of a portion of the subjects in the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) study ...
Mangialasche F F Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden. - - 2013
The aim of this study was to evaluate the accuracy of combined structural magnetic resonance imaging (MRI) measures and plasma levels of vitamin E forms, including all eight natural vitamin E congeners (four tocopherols and four tocotrienols) and markers of vitamin E oxidative/nitrosative damage, in differentiating individuals with Alzheimer's disease ...
Filippi Massimo - - 2013
Evaluation of: Løken-Amsrud KI, Myhr KM, Bakke SJ et al. Retinol levels are associated with magnetic resonance imaging outcomes in multiple sclerosis. Mult. Scler. doi:10.1177/1352458512457843 (2012) (Epub ahead of print). A combination of genetic and environmental factors probably plays a role in determining an increased susceptibility to multiple sclerosis (MS). Among these ...
Gürsoy Azize Esra - - 2013
Subacute combined degeneration (SCD) is a rare neurological complication of vitamin B12 deficiency, characterized by demyelination of the dorsal and lateral spinal cord. Herein, we describe three cases, who presented with SCD, one related to reduced intake of vitamin B12 because of a vegetarian diet and two related to nitrous ...
de Kubber Marije M - - 2013
Splenic injury is normally associated with trauma, but spontaneous splenic rupture has been described in various systemic diseases. A 56-year-old male on oral anticoagulation presented to the emergency department with epigastric pain, nausea, and left upper quadrant tenderness. There was no history of trauma. Contrast-enhanced CT imaging revealed a large ...
Cavalieri Margherita - - 2012
BACKGROUND AND PURPOSE: Elevated concentrations of homocysteine are associated with cerebral small vessel disease (CSVD). B-vitamin supplementation with folate and vitamins B(12) and B(6) reduces homocysteine concentrations. In a substudy of the VITAmins TO Prevent Stroke (VITATOPS) trial, we assessed the hypothesis that the addition of once-daily supplements of b ...
Rosenbaum David - - 2012
18F-FDG PET is a new noninvasive tool for inflammation functional imaging. Low spatial resolution is now compensated by coregistration with CT or MRI. New mechanistic insights have emerged from animal and histology to explain the obtained signals by hypoxia, macrophage infiltration, and differentiation. Mixed results have been found in biomarkers ...
Medel Ricky R Department of Neurosurgery, University of Virginia Health Sciences Center, University of University, Charlottesville, Virginia 22902, - - 2012
Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is a novel combination of technologies that is actively being realized as a noninvasive therapeutic tool for a myriad of conditions. These applications are reviewed with a focus on neurological use. A combined search of PubMed and MEDLINE was performed to identify the key ...
Bettinardi Valentino - - 2012
Hybrid positron emission tomography (PET)/computed tomography (CT) scanners combine, in a unique gantry, 2 of the most important diagnostic imaging systems, a CT and a PET tomograph, enabling anatomical (CT) and functional (PET) studies to be performed in a single study session. Furthermore, as the 2 scanners use the same ...
Garg Madhur K - - 2012
The introduction of image-guided radiation therapy and intensity-modulated radiation therapy has led to unparalleled advances in achieving precise dose conformality in radiation therapy and ushered in new possibilities in organ preservation. Without the ability to meticulously delineate radiation treatment volumes, these advantages would be clinically irrelevant. Positron emission tomography (PET)/computed ...
Scripes Paola G - - 2012
The usage of functional data in radiation therapy (RT) treatment planning (RTP) process is currently the focus of significant technical, scientific, and clinical development. Positron emission tomography (PET) using ((18)F) fluorodeoxyglucose is being increasingly used in RT planning in recent years. Fluorodeoxyglucose is the most commonly used radiotracer for diagnosis, ...
Hayter Catherine L - - 2012
Overuse and traumatic injuries of the elbow are common, occurring in both athletes and nonathletes. This article will discuss the commonly encountered soft-tissue and osseous pathologic abnormalities around the elbow and their imaging appearance on MRI and ultrasound. The current treatment of tendon disease of the elbow is reviewed, with ...
Jolly K - - 2012
A 58-year-old white woman presented with sudden onset of diplopia, headache and vomiting with a history of tiredness and lethargy over the past four to six months. She had smooth, pale, hairless skin and on examination she was found to have left-sided third and sixth nerve palsy. Laboratory tests confirmed ...
Akita S - - 2012
Effective therapy for chronic radiation injuries, such as ulcers, is prone to infection. Stiffness is expected since the therapeutic radiation often involves wider and deeper tissues and often requires extensive debridement and reconstruction, which are not sometimes appropriate for elderly and compromised hosts. Autologous adipose-derived regenerative cells (ADRCs) are highly ...
Garcia Camilo - - 2012
PURPOSE OF REVIEW: F-fluoro-2-deoxy-D-glucose PET-computed tomography (CT) has a major clinical impact in oncology not only for diagnostics but also for staging, response assessment, and relapse detection. However, several other PET tracers are needed for a more complete molecular characterization of cancers which has great importance in the era of ...
Dennhag Inga - - 2012
Abstract The current study examined the agreement between supervisors' and independent judges' evaluations of therapist adherence and competence in three treatments of cocaine dependence: supportive expressive therapy (SE), cognitive therapy CT), and individual drug counseling (IDC). We used data from The National Institute on Drug Abuse Collaborative Cocaine Treatment Study ...
Vilanova J C - - 2012
Magnetic resonance imaging (MRI) is the technique of choice in the diagnosis, staging, and follow-up of musculoskeletal tumors. Diffusion imaging is a new functional MRI technique that provides information that is complementary to that obtained in conventional MRI sequences. Diffusion imaging has proven useful in different clinical situations like the ...
Tomasi Giampaolo - - 2012
Among the methods based on molecular imaging, the measure of the tracer uptake variation between a baseline and follow-up scan with the SUV and [(18)F]FDG-PET/CT is a very powerful tool for assessing response to treatment in oncology. However, the development of new targeted therapeutics and tissue pharmacokinetic evaluation of existing ...
Shinagare A B - - 2012
AIM: To assess the incidence, appropriateness, and outcomes of recommendations for additional imaging tests (RAI) in oncological combined 2-[(18)F]-fluoro-2-deoxy-d-glucose positron-emission tomography and computed tomography (FDG-PET/CT) reports. MATERIAL AND METHODS: In this retrospective study, conducted with institutional review board approval, the first oncological FDG-PET/CT reports in 2008 for 250 consecutive patients ...
Zamagni Elena - - 2012
Bone disease is the major feature of multiple myeloma (MM). Imaging is required for correct staging, in the follow-up after treatment and, as recently highlighted, is predictor of prognosis. In the near future, whole-body X-Ray may be replaced by more sensitive techniques, such as whole-body low-dose computerized tomography (CT). Magnetic ...
Haney C R - - 2012
Sorafenib is a multi-kinase inhibitor that blocks cell proliferation and angiogenesis. It is currently approved for advanced hepatocellular and renal cell carcinomas in humans, where its major mechanism of action is thought to be through inhibition of vascular endothelial growth factor and platelet-derived growth factor receptors. The purpose of this ...
Jenne Jürgen W - - 2012
In the past two decades, high-intensity focused ultrasound (HIFU) in combination with diagnostic ultrasound (USgFUS) or magnetic resonance imaging (MRgFUS) opened new ways of therapeutic access to a multitude of pathologic conditions. The therapeutic potential of HIFU lies in the fact that it enables the localized deposition of high-energy doses ...
Soga S - - 2012
SUMMARY:Facial allotransplantation replaces missing facial structures with anatomically identical tissues, providing desired functional, esthetic, and psychosocial benefits far superior to those of conventional methods. On the basis of very encouraging initial results, it is likely that more procedures will be performed in the near future. Typical candidates have extremely complex ...
Martinez-Möller Axel - - 2012
Integrated PET/MRI systems open exciting possibilities for clinical and research applications. However, compared with PET/CT, PET/MRI is a complex technique resulting in new problems and challenges, especially regarding workflow, scan protocols, and data analysis. This complexity applies in particular to examinations in oncology with partial- or whole-body coverage extending over ...
Kalemis Antonis A Philips Healthcare, Guildford Business Park, Guildford, Surrey GU2 8XH, UK. - - 2013
PET and MRI are established clinical tools which provide complementary information, but clinical workflow limits widespread clinical application of both modalities in combination. The two modalities are usually situated in different hospital departments and operated and reported independently, and patients are referred for both scans, often consecutively. With the advent ...
Francois Mercier - - 2012
Lesion count observed on brain magnetic resonance imaging scan is a common end point in phase 2 clinical trials evaluating therapeutic treatment in relapsing remitting multiple sclerosis (MS). This paper compares the performances of Poisson, zero-inflated poisson (ZIP), negative binomial (NB), and zero-inflated NB (ZINB) mixed-effects regression models in fitting lesion ...
Cowell Gordon W - - 2012
This review aims to establish the impact on conventional angiography and endovascular intervention of contrast-enhanced magnetic resonance angiography (CE-MRA) and contrast-enhanced computed tomography angiography (CE-CTA) on a background of evolving technology, changing clinical requirements and resulting clinical repercussions. The angiographic and interventional caseload was prospectively recorded between 1997 and 2010, ...
Priola Adriano M - - 2012
INTRODUCTION: To prospectively evaluate the frequency and spectrum of incidental findings (IF) in a 5-year lung cancer screening program with low-dose spiral computed tomography (CT) and to estimate the additional costs of their imaging workup incurred from subsequent radiologic follow-up evaluation. MATERIALS AND METHODS: A total of 519 asymptomatic volunteers ...
Heiss John D - - 2012
: Surgically remediable medically intractable epilepsy usually arises from mesial temporal sclerosis. Standard treatment requires surgical removal of the affected hippocampus, which eliminates seizures in 2/3 patients. Less invasive therapies have been advocated. We are developing therapy using muscimol, a GABA-A agonist, to focally suppress the epileptic focus. : A ...
Koento Trimartani - - 2012
This review summarizes the current advances in sinus preservation techniques with endoscopic sinus surgery for the well tolerated and effective management of frontal sinus fractures. Advances in computed tomography (CT) imaging can now reproduce higher quality reformatted images, creating excellent diagnostic coronal, axial, and sagittal image views that provide a ...
Li Min - - 2012
This article describes a case of a 13-year-old girl with single-level calcified cervical disk herniation. The patient was treated conservatively for a symptomatic intervertebral calcification that caused neurological compression, and the data were reviewed retrospectively. Previous reports have shown that the natural history of the disease is self-limiting with a ...
Herholz Karl - - 2012
PET with the glucose analog FDG as a tracer is a mature and increasingly available clinical imaging technique that can improve the diagnostic accuracy for Alzheimer's disease, which is of particular value at an early stage of the disease when clinical symptoms are still mild and nonspecific. It can also ...
Kircher Moritz F - - 2012
Molecular imaging is expected to have a major impact on the early diagnosis of diseases and disease monitoring in the next decade. Traditionally, nuclear imaging techniques have been the mainstay of molecular imaging in the clinical arena. However, with continued development of molecularly targeted contrast agents for nonnuclear imaging techniques ...
Yap Ki S - - 2012
The emergence of hybrid imaging, combining anatomical computed tomography (CT) and functional single-photon emission computed tomography (SPECT), has greatly expanded the armoury available to image disease. Integrated SPECT-CT is a dual-modality technique, which improves the sensitivity and specificity of existing radionuclide studies and enables characterization of equivocal findings detected by ...
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