Search Results
Results 351 - 400 of 1314
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Ali Syed A - - 2010
OBJECTIVE: The objective of our study was to assess patellofemoral measurements on MRI and to correlate the measurements with different grades of cartilage defect. MATERIALS AND METHODS: Axial and sagittal MR images of 100 patients with various pathologic knee conditions were analyzed. The patients were divided into two age groups: ...
Hunter D J - - 2010
Prior investigations of magnetic resonance imaging (MRI) biomarkers of cartilage loss in knee osteoarthritis (OA) suggest that trials of interventions which affect this biomarker with adequate statistical power would require large clinical studies of 1-2 years duration. We hypothesized that smaller, shorter duration, "Proof of Concept" (PoC) studies might be ...
Vasiliadis Haris S - - 2010
BACKGROUND: Various treatment options are available for articular cartilage lesions, but controversy exists regarding the quality of the repair tissue and the durability of the results posttreatment. Noninvasive techniques are needed for the assessment of the repair tissue. HYPOTHESIS: Magnetic resonance imaging (MRI) with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) ...
Williams A A Cartilage Restoration Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15213, United - - 2010
To examine the sensitivity of ultra-short echo time (UTE) T(2)* mapping to collagen matrix degeneration in human articular cartilage. Magnetic resonance imaging (MRI) UTE-T(2)* maps and standard T(2) maps were acquired on four human tibial plateau explants. Thirty-three osteochondral cores were harvested for polarized light microscopy (PLM), and composition analyses. ...
Friedrich Klaus M - - 2011
To evaluate qualitative and quantitative image quality parameters of isotropic three-dimensional (3D) cartilage-imaging magnetic resonance (MR)-sequences at 3T. The knees of 10 healthy volunteers (mean age, 24.4±5.6 years) were scanned at a 3T MR scanner with water-excited 3D Fast-Low Angle Shot (FLASH), True Fast Imaging with Steady-state Precession (TrueFISP), Sampling ...
Raynauld Jean-Pierre - - 2010
The aim of the study was to evaluate by quantitative magnetic resonance imaging the effect of celecoxib 200 mg daily on cartilage volume loss over 12 months in knee osteoarthritis. The primary outcome of this study was to evaluate cartilage volume loss in the medial compartment of the knee (femoral ...
Potter Hollis G - - 2010
The relatively thin cartilage of the hip joint, as well as its complex geometry, poses challenges for standardized, reproducible assessment of cartilage and the acetabular labrum. With appropriate pulse sequence parameters, however, accurate, reproducible assessment of cartilage and the labrum is feasible. More detailed evaluation of cartilage biochemistry may be ...
Monden Satoshi S Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, Gunma 371-8511, Japan. - - 2010
The progress of diagnostic imaging technology, including CTs, MRIs, and ankle arthroscopy has encouraged more detailed descriptions of osteochondral lesions of the talus. These lesions can vary from chondral fragments separated from the subchondral bone with or without bone sclerosis or cysts in the subchondral layers. Isolated lesions of the ...
Buck Florian M - - 2010
OBJECTIVE: The purpose of this study was to evaluate the physiologic extent and thickness of the cartilage and bare areas of the distal radioulnar joint with gross anatomic examination, MRI, and MR arthrography with the forearm in neutral position, maximal pronation, and maximal supination. MATERIALS AND METHODS: MRI and MR ...
Ogino Shuhei - - 2010
BACKGROUND: Incidental articular cartilage lesions of the far posterior femoral condyle (FPFC) are commonly detected. Whether or not these cartilage lesions are symptomatic or clinically significant is unknown. PURPOSE: To characterize and assess prevalence of articular cartilage abnormalities of the FPFC and associated bone marrow edema (BME) and/or internal derangements ...
Mamisch Tallal C TC Department of Orthopedic Surgery, University of Berne, Berne, - - 2010
To prospectively determine on T2 cartilage maps the effect of unloading during a clinical magnetic resonance (MR) examination in the postoperative follow-up of patients after matrix-associated autologous chondrocyte transplantation (MACT) of the knee joint. Ethical approval for this study was provided by the local ethics commission, and written informed consent ...
Augsburger Sam - - 2010
A magnetic emergency release system was developed for use in halo traction systems. Commercially available rare earth mounting magnets, with selected weight-carrying capacities, along with ferromagnetic receptacles, were used in line between halos and overhead pulleys to both carry the prescribed traction force and provide an emergency release in the ...
von Engelhardt Lars V - - 2010
In patients with osteoarthritis, a detailed assessment of degenerative cartilage disease is important to recommend adequate treatment. Using a representative sample of patients, this study investigated whether MRI is reliable for a detailed cartilage assessment in patients with osteoarthritis of the knee. In a cross sectional-study as a part of ...
Seeuws Sylvie - - 2010
Disease severity in collagen-induced arthritis (CIA) is commonly assessed by clinical scoring of paw swelling and histological examination of joints. Although this is an accurate approach, it is also labour-intensive and the application of less invasive and less time-consuming methods is of great interest. However, it is still unclear which ...
Le Graverand M-P Hellio - - 2010
OBJECTIVE: Cartilage morphology displays sensitivity to change in osteoarthritis (OA) with quantitative MRI (qMRI). However, (sub)regional cartilage thickness change at 3.0 Tesla (T) has not been directly compared with radiographic progression of joint space narrowing in OA participants and non-arthritic controls. METHODS: A total of 145 women were imaged at ...
Andreisek Gustav - - 2010
PURPOSE: To assess the feasibility and accuracy of a synthetic-echo time (TE) magnetic resonance (MR) postprocessing technique for the diagnostic evaluation of abnormalities of menisci and articular cartilage in the knee. MATERIALS AND METHODS: This study was approved by the institutional review board. Twenty-four patients (three women, 21 men; mean ...
von Engelhardt Lars V - - 2010
Lateral dislocation of the patella (LPD) leads to cartilaginous injuries, which have been reported to be associated with retropatellar complaints and the development of patellofemoral osteoarthritis. Therefore, the purpose of this study was to determine the reliability of MRI for cartilage diagnostics after a first and recurrent LPD. After an ...
Zheng Shaokuan S Department of Physics and Center for Biomedical Research, Oakland University, Rochester, Michigan 48309, - - 2010
The relaxivities (R-values) of the gadolinium diethylene triamine pentaacetic acid (Gd(DTPA)2-) ions in a series of skim-milk solutions at 0-40% milk concentrations were measured using NMR spectroscopy. The R-value was found to be approximately linearly proportional to the concentration of the solid component in the milk solution. Using the R-value ...
Goebel Jean-Christophe - - 2010
Due to the actual interest for bioengineering in the osteoarthritis (OA) healing context, researchers need accurate qualitative and quantitative methodologies to evaluate in vivo the integration and functionality of their cartilage-like biomaterials. As in clinical diagnostic strategies, advances in Magnetic Resonance Imaging (MRI) seem promising for non-vulnerant assessments of articular ...
Rafiq Muhammad Khizar - - 2010
An intravenous drug abuser with a retained needle posed a management problem at a neurosurgical unit, having declined magnetic resonance imaging (MRI) on safety grounds. However, later, having been assessed by the senior radiologist, she went though the MRI scan safely.
Stehling Christoph C Musculoskeletal and Quantitative Imaging Group, Department of Radiology, University of California San Francisco, 185 Berry St, Suite 350, San Francisco, CA 94107, USA. - - 2010
To study the interrelationship between patella cartilage T2 relaxation time, other knee abnormalities, and physical activity levels in asymptomatic subjects from the Osteoarthritis Initiative (OAI) incidence cohort. The study had institutional review board approval and was HIPAA compliant. One hundred twenty subjects from the OAI without knee pain (age, 45-55 ...
Dietrich Tobias Johannes - - 2010
OBJECTIVE: To evaluate the diagnostic performance of MR arthrography in the detection of articular cartilage and labral lesions of the glenohumeral joint using a transverse 3D water-excitation true fast imaging with steady-state precession (FISP) sequence. MATERIALS AND METHODS: Seventy-five shoulders were included retrospectively. Shoulder arthroscopy was performed within 6 months ...
Lee Yeom Sik - - 2010
RATIONALE AND OBJECTIVES: This study was designed to demonstrate the feasibility of the use of phase-contrast computed tomographic (CT) imaging for the identification of articular cartilage abnormalities of the knees in a mouse model of collagen-induced arthritis. MATERIALS AND METHODS: Arthritis was induced in nine male DBA/1 J mice by ...
Koo Seungbum S School of Mechanical Engineering, Chung-Ang University, Seoul 156-756, South - - 2009
Cartilage morphology change is an important biomarker for the progression of osteoarthritis. The purpose of this study was to assess the accuracy of in vivo cartilage thickness measurements from MR image-based 3D cartilage models using a laser scanning method and to test if the accuracy changes with cartilage thickness. Three-dimensional ...
Olive J - - 2009
REASONS FOR PERFORMING STUDY: Marginal osteophytes represent a well known component of osteoarthritis in man and animals. Conversely, central subchondral osteophytes (COs), which are commonly present in human knees with osteoarthritis, have not been reported in horses. OBJECTIVES: To describe and compare computed radiography (CR), single-slice computed tomography (CT), 1.5 ...
Bittersohl Bernd - - 2009
The purpose of this study was to assess if delayed gadolinium MRI of cartilage using postcontrast T(1) (T(1Gd)) is sufficient for evaluating cartilage damage in femoroacetabular impingement without using noncontrast values (T(10)). T(1Gd) and DeltaR(1) (1/T(1Gd) - 1/T(10)) that include noncontrast T(1) measurements were studied in two grades of osteoarthritis ...
O'Brien J - - 2011
The purpose of our study was to describe the magnetic resonance imaging (MRI) features of bipartite patella in asymptomatic patients. The study was prospective in type and performed following institutional ethical committees approval. In total, 25 subjects were recruited into the study and informed consent obtained in each case. The ...
Welsch Goetz H - - 2010
OBJECTIVES: To use T2 and T2* mapping in patients after matrix-associated autologous chondrocyte transplantation (MACT) of the knee, and to compare and correlate both methodologies. METHODS: 3.0-Tesla MRI was performed on 30 patients (34.6 +/- 9.9 years) with a follow-up period of 28.1 +/- 18.8 months after MACT. Multi-echo, spin-echo-based ...
Mosher T J TJ Penn State Center for NMR Research, Department of Radiology, The Penn State Milton S. Hershey Medical Center, Hershey, PA 17033, USA. - - 2010
To characterize effects of age and physical activity level on cartilage thickness and T2 response immediately after running. Institutional review board approval was obtained and all subjects provided informed consent prior to study participation. Cartilage thickness and magnetic resonance imaging (MRI) T2 values of 22 marathon runners and 15 sedentary ...
Buck R J - - 2010
OBJECTIVE: To explore whether longitudinal change in cartilage thickness in femorotibial subregions of knees with radiographic osteoarthritis (ROA) differs from that in healthy knees. METHODS: 3T coronal magnetic resonance (MR) images were acquired in 152 women at seven clinical centers at baseline (BL) and 24 months. Knees from 75 women ...
Li Xiao-ming - - 2009
BACKGROUND: There is a strong need for quick noninvasive diagnostic technique that can give a valid estimate of the status of the cartilage reliably, discriminating intact cartilage from various grades of impaired cartilage. The goal of this study was to assess the incidence of knee cartilage injuries and compare the ...
Liu Fang F Bioengineering Laboratory, Department of Orthopaedic Surgery, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, GRJ 1215, Boston, MA 02114, - - 2010
The knowledge of articular cartilage contact biomechanics in the knee joint is important for understanding the joint function and cartilage pathology. However, the in vivo tibiofemoral articular cartilage contact biomechanics during gait remains unknown. The objective of this study was to determine the in vivo tibiofemoral cartilage contact biomechanics during ...
Goodwin Douglas W - - 2009
Magnetic resonance (MR) imaging of the knee is capable of accurately identifying and characterizing cartilage injuries and degeneration. Optimal cartilage imaging requires an understanding of the relationship between cartilage structure and the MR image, acquisition of images with adequate resolution, a purposeful interrogation of the images by a reviewer possessing ...
Kwack Kyu-Sung - - 2009
BACKGROUND: The proximal tibiofibular joint (PTFJ) can be considered the fourth compartment of the knee joint. However, there have been no studies of the T2 values (T2 relaxation time) of PTFJ cartilage. PURPOSE: To assess the T2 values of PTFJ cartilage at 3T magnetic resonance imaging (MRI), and to show ...
Silvast Tuomo S - - 2009
Charged contrast agents have been used both in vitro and in vivo for estimation of the fixed charge density (FCD) in articular cartilage. In the present study, the effects of molecular size and charge on the diffusion and equilibrium distribution of several magnetic resonance imaging (MRI) and computed tomography (CT) ...
Pepin Scott R - - 2009
BACKGROUND: There has recently been increased interest in the use of 7.0-T magnetic resonance imaging for evaluating articular cartilage degeneration and quantifying the progression of osteoarthritis. PURPOSE: The purpose of this study was to evaluate articular cartilage cross-sectional area and maximum thickness in the medial compartment of intact and destabilized ...
Yu Lifeng - - 2009
Despite universal consensus that computed tomography (CT) overwhelmingly benefits patients when used for appropriate indications, concerns have been raised regarding the potential risk of cancer induction from CT due to the exponentially increased use of CT in medicine. Keeping radiation dose as low as reasonably achievable, consistent with the diagnostic ...
Bittersohl Bernd - - 2009
This study defines the feasibility of utilizing three-dimensional (3D) gradient-echo (GRE) MRI at 1.5T for T(2)* mapping to assess hip joint cartilage degenerative changes using standard morphological MR grading while comparing it to delayed gadolinium-enhanced MRI of cartilage (dGEMRIC). MRI was obtained from 10 asymptomatic young adult volunteers and 33 ...
Joshi Neel S - - 2009
The synthesis and evaluation of a new class of cationic iodinated contrast agents for the imaging of cartilage using computed tomography (CT) are described. In direct comparisons with anionic contrast agents, the cationic contrast agents afforded higher equilibrium concentrations in the articular cartilage of ex vivo rabbit femurs and thus ...
Eckstein Felix - - 2009
To determine by magnetic resonance imaging (MRI), whether knees with advanced radiographic disease (medial joint space narrowing [mJSN]) encounter greater longitudinal cartilage loss than contralateral knees with earlier disease (no or less mJSN). Participants were selected from 2,678 cases in the Osteoarthritis Initiative, based on exhibition of bilateral pain, body ...
Roemer F W FW Quantitative Imaging Center (QIC), Department of Radiology, Boston University Medical Center, Boston, MA 02118, USA. - - 2010
To date semiquantitative whole-organ scoring of knee osteoarthritis (OA) relies on 1.5 Tesla (T) Magnetic resonance imaging (MRI) systems. Less costly 1.0 T extremity systems have been introduced that offer superior patient comfort, but may have limitations concerning field-of-view and image quality. The aim of this study was to compare ...
Welsch Goetz H - - 2009
INTRODUCTION: Cartilage defects are common pathologies and surgical cartilage repair shows promising results. In its postoperative evaluation, the magnetic resonance observation of cartilage repair tissue (MOCART) score, using different variables to describe the constitution of the cartilage repair tissue and the surrounding structures, is widely used. High-field magnetic resonance imaging ...
Wang Ligong L Center for Biomedical Imaging, New York University Langone Medical Center, New York, NY, USA. - - 2009
To demonstrate the feasibility of acquiring high-resolution, isotropic 3D-sodium magnetic resonance (MR) images of the whole knee joint in vivo at ultrahigh field strength (7.0T) via a 3D-radial acquisition with ultrashort echo times and clinically acceptable acquisition times. Five healthy controls (four males, one female; mean +/- standard deviation [SD] ...
Gold Garry E GE Department of Radiology, Stanford University, 300 Pasteur Dr., Grant Bldg. S0-68B, Stanford, CA 94305-5105, USA. - - 2009
MRI is the most accurate noninvasive method available to diagnose disorders of articular cartilage. Conventional 2D and 3D approaches show changes in cartilage morphology. Faster 3D imaging methods with isotropic resolution can be reformatted into arbitrary planes for improved detection and visualization of pathology. Unique contrast mechanisms allow us to ...
Streitparth F - - 2009
BACKGROUND: Biodegradable scaffolds have become an important option in the treatment of osteochondral defects. Therefore, accurate and reproducible monitoring of scaffold repair tissue is crucial. PURPOSE: To assess the feasibility of indirect magnetic resonance (MR) arthrography in determining the quality of osteochondral repair after scaffold implantation using an MR imaging ...
Notohamiprodjo Mike - - 2009
PURPOSE: To clinically evaluate MRI of the knee using a highly resolved isotropic fat-saturated (fs) proton-density weighted 3D-TSE-sequence (SPACE) at 3T. MATERIALS AND METHODS: Imaging was performed on a 3T-scanner (Magnetom TRIO). For technical evaluation, sagittally orientated SPACE-datasets (repetition-time [TR], 1200 milliseconds/[TE], 30 milliseconds/voxel-size, 0.5 mm3/acquisition time, 10:35 minutes) were ...
Hunter D J - - 2010
Based on recent analyses, the measures of short-term responsiveness of magnetic resonance imaging (MRI) derived cartilage morphometry may not be as large as earlier studies had suggested. We examined if by selecting regions of interest with denuded cartilage, the remaining cartilage within this region of interest was susceptible to greater ...
Kwack Kyu-Sung - - 2009
Background: The proximal tibiofibular joint (PTFJ) can be considered the fourth compartment of the knee joint. However, there have been no studies of the T2 values (T2 relaxation time) of PTFJ cartilage. Purpose: To assess the T2 values of PTFJ cartilage at 3T magnetic resonance imaging (MRI), and to show ...
Neu C P - - 2009
Non-invasive magnetic resonance imaging (MRI) is a technology that enables the characterization of multiple physical phenomena in living and engineered tissues. The mechanical function of engineered tissues is a primary endpoint for the successful regeneration of many biological tissues, such as articular cartilage, spine and heart. Here we demonstrate the ...
Roemer Frank W - - 2009
Whole organ magnetic resonance imaging (MRI)-based semiquantitative (SQ) assessment of knee osteoarthritis (OA), based on reliable scoring methods and expert reading, has become a powerful research tool in OA. SQ morphologic scoring has been applied to large observational cross-sectional and longitudinal epidemiologic studies as well as interventional clinical trials. SQ ...
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