Heart failure patients often develop cachexia, which is an independent factor for survival reduction. Cachexia can be diagnosed when there is loss of more than 6% of the body weight, in the absence of other diseases. Even though its pathophysiology has not yet been completely clarified, various factors seem to ...

ABSTRACT: It has been well-documented in the literature that resistance training can promote marked increases in skeletal muscle mass. Post-exercise hypertrophic adaptations are mediated by a complex enzymatic cascade whereby mechanical tension is molecularly transduced into anabolic and catabolic signals that ultimately leads to a compensatory response, shifting muscle protein ...

Oxygen (O2) is a vital element. Shortage of O2 results in deranged metabolism and important changes in vascular tone with opposite effects on the systemic and pulmonary circulation. During hypoxemia, oxidative stress exposes the organism to a sort of accelerated senescence as well as to several acute untoward effects. Thus, ...

Physical exercise has been related with both beneficial effects on the gastrointestinal tract as with adverse effects on the latter. Gastrointestinal bleeding is one of these. In general, gastrointestinal bleeding is transient and mild. However, some cases caused by intestinal ischemia can sometimes be more serious due to the amount ...

Voice quality disorders - dysphonias are the significant problem from therapeutic, social and economic point of view. The routine therapy does not always bring spectacular effects. The important role play the innovative methods supporting therapy of voice quality disorders. PURPOSE: The aim of the study is to assess the effects ...

A 50-year-old woman presented with fatigue and shortness of breath. Dyspnea after moderate exertion had developed gradually, along with profound malaise and a nonproductive cough. In the 48 hours before admission, her shortness of breath had worsened.

Traditional approaches to patient-reported outcomes diaries have been largely paper based. However, paper-based approaches have inherent inefficiencies such as an inability to communicate the entries in real time to the healthcare team, issues related to transport and mobility, and no tailored output related to what is entered. Traditional paper-based approaches ...

Hepatic lipase (HL) and lipoprotein lipase (LPL) activities (HLA, LPLA) modify lipoproteins and facilitate their binding to hepatic receptors. Apolipoprotein E (APOE) physically interacts with the lipases, and the three common haplotypes of the APOE gene (ε2, ε3, and ε4) yield protein isoforms (E2, E3, and E4, respectively) that are ...

Sex work research continues to be characterised by debates around decriminalization. Central to these debates are claims about the agency of those involved in the sex trade. Some researchers argue that individuals involved in the sex trade are victims of structural and interpersonal constraint, whilst others depict them as workers ...

Clinical clerkship directors and faculty undertake the challenge of teaching patient-centered communication to students who face the enormous doctor-centered task of learning diagnostic medicine. The authors examined students' written reactions to the narrative exercise, which, drawing from narrative medicine and narrative therapy, challenges students to be more patient-centered by writing ...

Acid/base homeostasis is one of the most difficult subdisciplines of physiology for medical students to master. A different approach, where theory and practice are linked, might help students develop a deeper understanding of acid/base homeostasis. We therefore set out to develop a laboratory exercise in acid/base physiology that would provide ...

In October 2009, the International Atomic Energy Agency (IAEA) sponsored an intercomparison exercise of surface contamination monitoring equipment, which was held at the Laboratório Nacional de Metrologia das Radiações Ionizantes, from the Instituto de Radioproteção e Dosimetria, IRD/CNEN, Rio de Janeiro. This intercomparison was performed to evaluate the calibration accessibility ...

A training course named 'European Radiation Dosimetry Group/International Atomic Energy Agency Advanced Training Course on Internal Dose Assessment' was held in Czech Technical University in Prague from 2 to 6 February 2009. The course, jointly organised by the two organisations, had the aim of providing guidance on the application of ...

Cardiopulmonary exercise testing (CPX) is a relatively old technology, but has sustained relevance for many primary care clinical scenarios in which it is, ironically, rarely considered. Advancing computer technology has made CPX easier to administer and interpret at a time when our aging population is more prone to comorbidities and ...

This paper describes recruitment challenges and lessons learned in conducting a randomized controlled exercise trial in the absence of direct access to a clinical population. One-hundred thirty-five wheelchair users were enrolled in a home and community-based intervention to promote exercise adoption and maintenance. Over 44 months of recruitment, 355 individuals ...

As seen in the spring 2009 A/H1N1 influenza outbreak, influenza pandemics can have profound social, legal and economic effects. This experience has also made the importance of public health preparedness exercises more evident. Universities face unique challenges with respect to pandemic preparedness due to their dense student populations, location within ...

An in vivo intercomparison exercise, organised in the scope of the IAEA Regional Latin American (RLA) Project 9066, was carried out in 2009 aimed to harmonise measurement procedures on the measurement of (131)I in the thyroid among Latin American and Caribbean countries. The exercise consisted in the measurement of an ...

CONTEXT: The anthrax incident of 2001 in the United States prompted the College of American Pathologists (CAP), the Association of Public Health Laboratories, and the Centers for Disease Control and Prevention to develop exercises for Laboratory Response Network (LRN) sentinel laboratories. OBJECTIVE: To provide an overview of the results of ...

Ultimately what we do as doctors is intervene in our patients to alleviate symptoms (palliate), or reduce risk (prevent), or abort (cure) disease processes. Such interventions do not have to be drugs. They can be simple prognostic reassurance, an exercise regimen, counselling, meditation, or any other modality of care.

In this technical report, prepared following the kind invitation of Professor D'Amore, we describe the evolution in the methodology of performing the limb lymphoscintigraphy. In details we described and compared the rest protocol with subcutaneous injection of the radio-colloids vs. the exercise intradermal injection protocol. The latter appears to be ...

PURPOSE: Virtual reality surgical simulation is an emerging technology that may eventually fill the gaps in surgical education created by changes in our medical system. We assessed the construct validity of a commercially available, virtual reality transurethral prostate resection simulator. MATERIALS AND METHODS: Participants performed 2, 5-minute transurethral prostate resection ...

This exploratory study compared the screening ability of a newly introduced radiation detection portal with a traditional Geiger counter for detection of radiation contamination in the setting of a mass casualty training exercise. Following a pretrial evaluation of interobserver reliability for Geiger counter use, 30 volunteers were randomly assigned to ...

In human societies, social behaviour is strongly influenced by threats of punishment, even though the threats themselves rarely need to be exercised. Recent experimental evidence suggests that similar hidden threats can promote cooperation and limit within-group selfishness in some animal systems. In other animals, however, threats appear to be ineffective. ...

The National Center for Food Protection and Defense (NCFPD), which is led by the University of Minnesota, hosted an international food defense exercise on 27 to 29 May 2008. Established in 2004, NCFPD is a Department of Homeland Security Center of Excellence with the mission of defending the food system ...

Exercise programmes for people with haemophilia are usually designed and implemented to help manage the recovery after a haemarthrosis or a muscle bleed, or as a tool to help prevent bleeding episodes from occurring. In this article, we have identified individual components of exercise that are often applied as separate ...

Cardiopulmonary exercise testing is a non-invasive, objective method of assessing integrated response of heart, lungs and musculoskeletal system to incremental exercise. Though it has been in use for a few decades, the recent rise in its use as a preoperative test modality is reviewed. A brief account of cardiopulmonary exercise ...

The educational objectives for this self-assessment module are for the participant to exercise, self-assess, and improve his or her understanding of the imaging spectrum of pediatric foot alignment issues.

Recent global and regional exercises have been undertaken to identify 100 questions of relevance to policy makers that, if answered, would improve decision making and conservation actions. These were intentionally broad, but all included themes and questions of relevance to aquatic and fisheries professionals (e.g. exploitation, habitat alteration, effectiveness of ...

Evidence-based practice (EBP) is a concept that was popularized in the early 1990s by several physicians who recognized that medical practice should be based on the best and most current available evidence. Although this concept seems self-evident, much of medical practice was based on outdated textbooks and oral tradition passed ...

The aim of this study was to investigate muscle activity, kinematic, and handgrip-force pattern generation during handcycling. One able-bodied participant performed a 1-min exercise test on a handcycle at 70 revolutions per minute. This article proposes an original data collection and analysis methodology that gathers synchronized kinematics, kinetics, and electromyography. ...

While the practice of using a smaller number of non-zero standards (typically seven to eight) has not been entertained in routine bioanalytical work, it is important to innovate and be pragmatic about minimizing the number of calibration standards to promote cost-effective and speedy assessment. In this exercise, two important compounds, ...

Hematologists/oncologists would provide essential care for victims of a catastrophic radiation incident, such as the detonation of an improvised nuclear device (IND). The US Radiation Injury Treatment Network (RITN) is a voluntary consortium of 37 academic medical centers, 8 blood donor centers, and 7 umbilical cord banks focused on preparedness ...

A survey by our department revealed that most of the institutions in New England and New York have written protocols for low-volume, high-risk, emergency events but few of these centers formally practice these protocols through simulation. We hypothesized that hands-on experience with medical emergency protocols will significantly improve clinician performance. ...

In recent years several authors have made a beginning in describing therapeutic conversations from a dialogical perspective. Training and supervision, however, have not yet been addressed from a dialogical perspective. In this article, an experiential training exercise is described that is focused on the basic dialogical skills of the trainee: ...

The past years have seen a broadening in the focus of emergency preparedness and first response towards situations involving the malevolent use of radioactive materials in a variety of contexts. Many of these contexts are such that first responders and responsible authorities may be faced with isotopes and activities that ...

Annual fire drills serve a valuable purpose in ensuring familiarity with evacuation procedures. However, the limited duration of these exercises may be far from the reality of a real incident. In this situation, the ability to return back into a building may be restricted for hours or days. As an ...

The response to an avian influenza outbreak, especially highly pathogenic avian influenza (HPAI), should focus on four basic principles: 1) protect humans first, 2) protect animals 3) contain the virus, and 4) ensure that the outbreak remains a single event, by preparing response teams to work together effectively through advance ...

Tabletop exercises are an excellent means for teaching people what a severe pandemic entails and for helping participants realise both the importance of planning and how to relate to an existing plan. Creating a one-page document to describe one's pandemic response plan and delineate trigger points enhances understanding of a ...

BACKGROUND: Infectious mononucleosis (IM) is common among university students. We undertook to analyze the clinical features and sequelae of the disease in a cohort of students at Edinburgh University. METHODS: Consecutive IM case patients were recruited from 2000 through 2002 at the University Health Service after diagnosis of IM. RESULTS: ...

We describe the case of a 32-year-old soldier who presented with acute organic psychosis during an operational tour to Iraq. This was precipitated by excessive consumption of caffeine coupled with additional use of oral nutritional stimulants. Her biochemical profile was compounded by the additional use of exogenous creatine. We present ...

Independent sustainability consultant and BREEAM healthcare assessor James Rainbird explains in detail how he recently helped a large primary care Trust in north-west England with its carbon footprinting. Arguing that PCTs face particular problems in collecting data, he believes there is a need for concise practical pointers to help Trusts ...

Tabletop exercises can be an effective strategy preparing for situations that involve numerous hospital departments, such as a pandemic surge. Here are some highlights of the successful tabletop exercises used by the Minneapolis and St. Paul EDs of Children's Hospitals and Clinics of Minnesota to prepare for last fall's H1N1 ...

Large, functional, disaster exercises are expensive to plan and execute, and often are difficult to evaluate objectively. Command and control in disaster medicine organizations can benefit from objective results from disaster exercises to identify areas that must be improved. The objective of this pilot study was to examine if it ...

The educational objectives for this self-assessment module are for the participant to exercise, self-assess, and improve his or her understanding of evaluation of scoliosis using radiography. The solutions to the questions in this activity review the imaging characteristics of radiologic evaluation of scoliosis.

The educational objectives for this self-assessment module are for the participant to exercise, self-assess, and improve his or her understanding of radiology in pediatric congenital sensorineural hearing loss, posterior plagiocephaly, and midline nasofrontal mass. The activities in these articles guide the participant to understanding the key concepts of radiology in ...

A collaborative exercise on mRNA profiling for the identification of blood was organized by the European DNA Profiling Group (EDNAP). Seven blood samples and one blood dilution series were analyzed by the participating laboratories for the reportedly blood-specific markers HBB, SPTB and PBGD, using different kits, chemistries and instrumentation. The ...

The Civil Contingencies Act (2004) requires UK primary care trusts (PCTs) to plan and respond to major health incidents. We carried out a cross-sectional survey of all PCTs in the north-west region of England using a telephone interview with a structured questionnaire. We assessed: (1) staff members responsible for emergency ...

An international exercise, registered as EUROMET project no. 907, was launched to measure both the activity of a solution of (124)Sb and the photon emission intensities of its decay. The same solution was sent by LNE-LNHB to eight participating laboratories. In order to identify possible biases, the participants were asked ...

OBJECTIVE: The purpose of this study was to examine the impact of the desirability of content on viewers' ratings of subjective video quality. BACKGROUND: Most subjective video quality studies use short-duration clips that are specially designed to exercise the encoding algorithms and do not consider the desirability of the content ...

An international exercise, registered as EUROMET project no. 907, was launched to measure both the activity of a solution of (124)Sb and the photon emission intensities of its decay. The same solution was sent by LNE-LNHB to eight participating laboratories, six of which sent results for photon emission intensities both ...