In earlier clinical studies of a group of children subjected to an intense fluoride treatment programme several salivary properties were related to cariogenic changes in the enamel surface, as assessed by mirror and probe. In this study the relationship between salivary parameters and cariogenic changes was investigated on bitewings taken ...

The activity of hypothalamic monoamines in response spontaneous feeding was investigated using the in vivo technique of brain microdialysis together with the instrumental recording of feeding pattern. The simultaneous variations of dopamine (DA), serotonin (5-HT), and their respective metabolites, DOPAC and 5-HIAA, were measured in the rostromedian hypothalamus, where the ...

Experience with young animals, animals administered certain hepatotoxins and animals with two-thirds hepatectomy suggests that tight junctional permeability is increased in states characterized by architectural remodeling in the liver. In this work we correlate changes in tight junctional morphometry induced by two-thirds hepatectomy with changes in biliary permeability assessed by ...

The introduction of the variable-pitch feature on pulse oximeters in 1983 by the Nellcor Corporation (Hayward, CA) allowed users to rapidly detect changes in oxygen saturation by listening for changes in the pitch of the tones emitted by the pulse oximeter. A few individuals have reported that they have been ...

Changes in biogenic amine levels associated with the morphological and behavioural development of the worker honeybee are examined. A significant increase in amine levels in the head of the honeybee is associated with transition from the larval to pupal stage. Adult emergence is also accompanied by a significant increase in ...

Subjects judged change and proportion when viewing graphs in two experiments. Change was judged more quickly and accurately with line and bar graphs than with pie charts or tiered bar graphs, and this difference was larger when the rate of change was smaller. Without a graduated scale, proportion was judged ...

We have previously demonstrated that administration of antisera against NGF (anti-NGF) can have profound effects on developing primary afferents (Ritter et al., 1991). Chronic administration of anti-NGF to rats beginning on the day of birth results in a severe depletion of cutaneous A delta high-threshold mechanoreceptors (HTMRs) from the sural ...

The changes in substance P concentrations in the hypothalamus of female golden hamsters were studied at the different stages of the estrous cycle. Substance P levels in the hypothalamus of hamsters were highest during estrus and lowest during diestrus I and proestrus. The concentrations of substance P during diestrus II ...

Arterial and venous systems are the main points for the evaluation of vasculogenic impotence. To evaluate both of these systems in the same study we propose a dual radioisotopic study in which 99mtechnetium (99mTc) and 133xenon (133Xe) were used. The changes in 99mTc and 133Xe radioactivities administered intravenously and intracavernously, ...

Carboxypeptidase N (CPN) is an inactivator of anaphylatoxins and kinins, peptides implicated in the pathogenesis of complications in extracorporeal circulation. To investigate whether the level of CPN is altered during cardiopulmonary bypass (CPB) we studied 15 patients undergoing cardiac surgery utilizing CPB. The concentration of CPN decreased to about 48% ...

Facial asymmetry and cosmetic deformity can occur following enucleation. The effect of enucleation on the growth of the orbit can be demonstrated in the rabbit and cat by early enucleation, X-ray study and dry skull measurements. In 42 human patients the anophthalmic orbital changes are determined by roentgenograms. The influencing ...

The concept of changes in emotional arousal during the binge-purge cycle plays a principal role in bulimia theory. Female bulimic patients (n = 29) retrospectively rated the intensity of several emotions during their binge-purge cycle. When collapsed into positive versus negative emotion categories, both categories showed significant changes in emotions ...

Dual-photon absorptiometry (DPA) has recently been applied to the assessment of body composition. To evaluate the accuracy of DPA in detecting small changes in the lean soft tissue mass, we performed DPA with the use of the Norland 2600 Dichromatic densitometer on six healthy adult males before and after a ...

The authors varied urea clearance (K), dialysis time (T), and ultrafiltration (UF) in 294 hemodialyses on 23 patients and studied changes in urea space (V), determined by total dialysate urea removal. As K increased and UF and T decreased, V also decreased. K, T, and V, thus, covariate and dialysis ...

Exercise was found to dilate the pupil area while the exercise took place, while the area showed constriction following the exercise period. Exercise-induced change in the size of the pupil was minimal. Pupillary dilation was greatest under conditions of maximal exercise. In exercise under a consistent load, pupillary dilation increased ...

The morphologic changes in ciliary processes and the associated intraocular pressure (IOP) were observed in owl and squirrel monkeys after intravitreal (IVT) and intravenous (IV) injections of water soluble marijuana-derived material (MDM). The response in monkeys differed from that reported in rabbits wherein IV injection induced severe ciliary swelling and ...

Myopathy represents one of the major features of Marinesco-Sjögren syndrome (MSS). Seven patients with MSS from three different families were studied with morphological and neurophysiological methods. In two patients ragged-red fibres were found after Gomori trichrome staining. Transmission electron microscopy (EM) showed that subsarcolemmal accumulation of abnormal mitochondria regularly occurred ...

Nucleolar changes and their time-course following axotomy and decentralization were investigated using an ultrastructural and stereological analysis of sympathetic neurons in superior cervical ganglion. By comparison with ganglia fixed immediately after removal, incubation for 2 h, 3 h and 5 h in NCTC 109 medium at 37 degrees C was ...

Two cohorts of suicide (and undetermined deaths) in Scotland for the quinquennia 1974-78, 1979-83 were investigated. A national record linkage exercise was carried out relating the deaths to admissions for alcoholism in the preceding 5 years (minimum) to 10 years (maximum). No differences were found between the cohorts in socio-demographic ...

1. Specific resistance to locomotion will remain constant if changes in the amount of force produced or in the cost of force production are directly proportional to changes in gravitational acceleration. 2. If changes in gravitational acceleration result in a disproportionate decrease of the effective mechanical advantage of limbs or ...

This study provides additional radiographic information concerning the long-term effect of ulnar impingement. Films of 198 wrists of 102 patients with vibration disease observed over ten or more years were reviewed. All the wrists showed ulnar plus variance of more than 0 mm except seven. Degenerative changes were found in ...

The vast literature on alcohol's effect on traffic safety does not contain even a moderately satisfactory answer to one of the most basic questions, namely "What is the fraction of all traffic fatalities attributable to alcohol use?" A published estimate of 23.7% based on an erroneous calculation has been widely ...

The inflammatory reactions in the teat and udder of the dry cow were studied by total and differential somatic cell counts (SCC) and by measuring bovine serum albumin, N-acetyl-beta-D-glucosaminidase (NAGase), plasminogen and plasmin. The teat and udder cisterns were surgically separated from each other in two udder quarters of each ...

Stimulation of the vestibular system by cold irritation of the ear was performed in 12 patients during a migraine attack. In eleven of the subjects the headache was changed. The changes varied from completely disappeared to a slight decrease. The duration of the changes was either several minutes, during the ...

Electrodermal activity (EDA) changes in menstrual cycle were studied in two experiments. In both experiments subjects were presented with 16 80-dB tones; 15 tones were 4 s, 1000 Hz, and the last one - change trial - was a 6-s, 3000-Hz tone. In Expt. 1, a within-subjects design was employed, ...

Free and total carbamazepine (CBZ) and carbamazepine-epoxide (CBZ-EP) plasma levels were obtained on 113 patients with epilepsy (18-61 years old) controlled on either monotherapy or coadministration with either phenobarbital (PB), phenytoin (PHT), valproic acid (VPA), or all three. A subset of patients were administered tetradeuterium labeled CBZ to evaluate the ...

Extravascular lung water (EVLW) can be measured using the double indicator dilution technique (DD). However, because this method is highly invasive and complicated, its clinical used has been limited. In theory, changes in thoracic conductivity, or bioimpedance (BI), can reflect changes in EVLW. However, past studies were unable to directly ...

During a cariogenic attack at the enamel surface a white spot can be formed (initiation) or disappear (regression) or remain the same (stabilisation). In the present clinical study it was shown that at least regression and stabilisation depend significantly on the posteruptive age and may be associated therefore with changes ...

In this study initially a precancerous condition, leukoplakia, was develop at 6 weeks treatment of DMBA whereas in the animals treated both DMBA + Vit. A, leukoplakia was seen at 10 weeks followed by papilloma or nodules at 12 weeks. Tumours induced by DMBA were more in number than DMBA ...

We have previously shown that the tilt aftereffect (TAE) appears to respond to changes in central dopaminergic function. In this study, the TAE was investigated during the preovulatory and the premenstrual phases of the menstrual cycle. Results in the preovulatory phase mimicked those previously found associated with increased dopaminergic function, ...

In this work we evaluate the cortical expansion model for amoeboid chemotaxis with regard to new information about molecular events in the cytoskeleton following chemotactic stimulation of Dictyostelium amoebae. A rapid upshift in the concentration of chemoattractant can be used to synchronize the motile behavior of a large population of ...

In an attempt to explain reverse T3 changes during protein supplemented semistarvation, reverse T3 (rT3) and T3 changes have been evaluated in regard of bw changes and changes of nutrient combustion. Significant (p less than 0.001) bw and body mass decrease was characterized by a significant (p less than 0.01) ...

The results of two procedures for measuring the loudness level of tinnitus will be presented. The traditional procedure yielded significantly smaller loudness matches, when expressed in decibel sensation level (i.e., dB SL), than did the Goodwin procedure. The Goodwin procedure is more sensitive to pharmacologically induced changes in tinnitus loudness ...

When turpentine was instilled into the right pleural cavity in rabbits a pleural effusion developed in half of the animals, with a low pH, low glucose concentration, high lactic dehydrogenase activity and the constant presence of rheumatoid arthritis cells in the affected pleural cavity. The biochemical values in the pleural ...

High performance liquid chromatography was utilized to characterize changes in the content of various steroids in adrenal glands with time postpartum. Adrenal glands were obtained from 32 beef cows on either days, 7, 14, 28, 42 or 56 after parturition (n = 6-8/group). Of the major glucocorticoids, only cortisone significantly ...

Frost-bite lesions were produced in five Hanford Miniature Swine exposed to - 75 degrees C air for 1, 3, 5, 10, or 20 min. Biopsies were taken at 0, 3, 6, 12, 24, and 48 h, and 1 and 2 weeks. Two hundred slides were evaluated microscopically: superficial and deep ...

The status of the blood-retinal barrier (BRB) in carriers of choroideremia and X-linked retinitis pigmentosa (XLRP) was determined by vitreous fluorophotometry (VF) and compared with that in female control subjects. Electroretinographic (ERG) amplitudes were measured to determine the overall functional integrity of retinal rods and cones. Comparison of the VF ...

The purpose of this report was to evaluate the magnitude of the regression towards the mean (RTM) relative to the observed changes in probing measurements following periodontal therapy in 2 groups of patients. Regression lines were calculated for observed changes in probing depths and probing attachment levels related to the ...

The effect of different surface areas on cellular, humoral, and hemodynamic changes and on plasma separation performance were investigated. Membrane plasmapheresis, consisting of plasma separation and on-line reinfusion, was carried out on dogs for 3 h with 0.6 and 0.3-m2 polyethylene (PE) and polyvinyl alcohol (PVA) modules. The plasma separation ...

A transient epidermal hyperplasia was induced in guinea pig epidermis by a single application of n-hexadecane. The epidermal response was analysed by light microscopy and by energy dispersive X-ray microanalysis (EDX). The epidermal hyperplasia reached a maximum between 96 and 192 h after the application. The hyperplastic response was associated ...

Exercise at a heart rate corresponding to 30% VO2max for 15 min was associated with an increase in the volume of bleeding time blood from a mean of 133 microliters before exercise to a mean of 218 microliters during and immediately after the exercise. There was similarly an increase in ...

The aim of the present study was to investigate the possible existence of rhythmicity of some morphological structures of the duodenum [correction of jejunum] in man. The height of intestinal villi was found to vary significantly during the 24 h time span, being higher during the day than during the ...

During the first 4 days following infection, early tegumentary changes are confined to the protoscolex soma of Echinococcus granulosus, the thick glycocalyx being lost and the blunt elevations, flattened. The Golgi complexes within the tegumentary cytons produce T2 vesicles that increase in number in the tegument from days 4 to ...

Acute pancreatitis is not the cause but may be a complication of chronic pancreatitis. Different forms of chronic pancreatitis are described. The most frequent type in all climates, chronic calcifying pancreatitis, has different causes but similar pathological changes. It is a lithiasis in which a new family of molecules. PSP, ...

Endometrial biopsy specimens (n = 62) were evaluated by five pathologists to assess the effect of interobserver variation on histologic dating of the endometrium. The potential effect of this variation on the diagnosis of luteal phase defects (LPDs) and resulting clinical management was also determined. Mean (+/- standard error) interobserver ...

We characterized the in vivo mechanical properties of segments of upper descending thoracic aorta (UDTA) in terms of volume distensibility, which was derived from measurements of pulsatile intravascular pressure, inner wall radius, and length changes. Data for this analysis were obtained from six dogs at rest and during moderate treadmill ...

In Bacillus subtilis, addition of chemotactic attractant causes an immediate change in distribution of methyl groups on methyl-accepting chemotaxis proteins (MCPs), whereas in Escherichia coli, it causes changes that occur throughout the adaptation period. Thus, methylation changes in B. subtilis are probably related to excitation, not adaptation. If labeled cells ...

The uptake rate of phenol by washed cells of Pseudomonas putidagrown on phenol in fermenter in an un steady state, caused by the step increase of dilution rate and/or phenol concentration in the feed, was studied. The Monod-Haldane type equation was applied to fit the data and the best kinetic ...

For substances eliminated from blood by the liver, the effect of a change in unbound fraction of drug (fu(b)) on steady state total (Cb) and unbound (Cu(b)) blood concentrations has hitherto only been considered for the two limiting cases, i.e., at the upper and lower extremes of hepatic intrinsic clearance ...

We assessed the mechanical properties of PC-12 neurites by applying a force with calibrated glass needles and measured resulting changes in neurite length and deflection of the needle. We observed a linear relationship between force and length change that was not affected by multiple distensions and were thus able to ...