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Spriet Lawrence L LL Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada, - - 2014
Caffeine is a popular work-enhancing supplement that has been actively researched since the 1970s. The majority of research has examined the effects of moderate to high caffeine doses (5-13 mg/kg body mass) on exercise and sport. These caffeine doses have profound effects on the responses to exercise at the whole-body level ...
Arida Ricardo Mario RM Departamento de Fisiologia, Universidade Federal de São Paulo/Escola Paulista de Medicina (UNIFESP/EPM), São Paulo- SP, Brazil; Hospital Israelita Albert Einstein, Instituto do Cérebro, São Paulo - SP, - - 2014
Physical exercise stimulates the release of endogenous opioid peptides purported to be responsible for changes in mood, anxiety, and performance. Exercise alters sensitivity to these effects that modify the efficacy at the opioid receptor. Although there is evidence that relates exercise to neuropeptide expression in the brain, the effects of ...
Galdino Giovane S GS Departament of Pharmacology, Federal University of Minas Gerais , Belo Horizonte , Brazil - - 2014
Abstract Resistance exercise is characterized to increase strength, tone, mass, and/or muscular endurance and also for produces many beneficial effects, such as blood pressure and osteoporosis reduction, diabetes mellitus control, and analgesia. However, few studies have investigated endogenous mechanisms involved in the resistance exercise-induced analgesia. Thus, the aim of this ...
Pareja-Blanco F F Faculty of Sport, Pablo de Olavide University, Seville, - - 2014
This study aimed to compare the effect on neuromuscular performance of 2 isoinertial resistance training programs that differed only in actual repetition velocity: maximal intended (MaxV) vs. half-maximal (HalfV) concentric velocity. 21 resistance-trained young men were randomly assigned to a MaxV (n=10) or HalfV (n=11) group and trained for 6 ...
Chen Chen-Yueh CY 1 Graduate Institute of International Sport Affairs, National Taiwan Sport - - 2014
Summary.-This study investigated the relationship between parents' passion for sport/exercise and children's self- and task-perceptions in sport and exercise. Paired samples of 312 children, 312 fathers, and 312 mothers were collected using two-stage sampling; parents were classified based on their passion for sport and exercise as high concordance if both ...
Lanzi S S Institute of Sport Sciences University of Lausanne (ISSUL), University of Lausanne, Lausanne, - - 2014
This study aimed to compare oxygen uptake (  V˙O2), hormone and plasma metabolite responses during the 30 min after submaximal incremental exercise (Incr) performed at the same relative/absolute exercise intensity and duration in lean (L) and obese (O) men. Eight L and 8 O men (BMI: 22.9±0.4; 37.2±1.8 kg · m-2) completed Incr and were ...
Di Luigi Luigi L Department of Movement, Human and Health Sciences, University of Rome "Foro Italico", Piazza Lauro de Bosis, 15, 00135, Rome, Italy, - - 2014
Endogenous glucocorticoids (GC) rapidly increase after acute exercise, and the phosphodiesterase's type 5 inhibitor (PDE5i) tadalafil influences this physiological adaptation. No data exist on acute effects of both acute exercise and PDE5i administration on 11β-hydroxysteroid dehydrogenases (11β-HSDs)-related GC metabolites. We aimed to investigate the rapid effects of exercise on serum ...
Pechlivanis Alexandros A Department of Chemistry, Aristotle University of Thessaloniki, 54124, - - 2014
Exhaustive exercise is a generator of free radicals and reactive species in mammals. Allopurinol is a known inhibitor of xanthine oxidase, a source of free radicals during exercise. In this study, the influence of allopurinol on the metabolic profile of blood plasma of rats that had undergone exhaustive swimming was ...
Ferreira Rita - - 2014
Moderate physical activity has traditionally been associated to the improvement of the cardiac function and, consequently, to the extension of the life span. Mitochondria play a key role in the adaptation of heart muscle to exercise-related metabolic demands. In order to disclose the molecular mechanisms underlying the beneficial effect of ...
Pareja-Galeano Helios H Department of Physiology, Faculty of Medicine, University of Valencia, Av. Blasco Ibáñez, 15, Valencia, 46010, Spain, - - 2014
Physical exercise induces several metabolic adaptations to meet increased energy requirements. Promoter DNA methylation, histone post-translational modifications, or microRNA expression are involved in the gene expression changes implicated in metabolic adaptation after exercise. Epigenetic modifications and many epigenetic enzymes are potentially dependent on changes in the levels of metabolites, such ...
Roberts Lee D LD Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, - - 2014
The transcriptional coactivator peroxisome proliferator-activated receptor-gamma coactivator-1α (PGC-1α) regulates metabolic genes in skeletal muscle and contributes to the response of muscle to exercise. Muscle PGC-1α transgenic expression and exercise both increase the expression of thermogenic genes within white adipose. How the PGC-1α-mediated response to exercise in muscle conveys signals to ...
Mukherjee Kamalika K Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, - - 2014
Exercise is beneficial for a variety of age-related disorders. However, the molecular mechanisms mediating the beneficial adaptations to exercise in older adults are not well understood. The aim of the current study was to utilize a dual approach to characterize the genetic and metabolic adaptive pathways altered by exercise in ...
Tuo Fei F Key Laboratory of Radiological Protection and Nuclear Emergency, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, - - 2013
Six comparison exercises on radioactivity measurement by γ-spectrometry have been organized by NIRP in China since 2007. The type of measured nuclides changed from natural to man-made over this period. A total of 188 samples were prepared and distributed to 39 different participating laboratories and 528 radionuclide assays have been ...
Valim Valéria - - 2013
To evaluate the effects of aerobic training and stretching on serum levels of serotonin (5HT) and its main metabolite 5-hydroxindolacetic acid (5HIAA). Twenty-two women with FM were randomized into one of two exercise modalities (aerobic walking exercise or stretching exercise) to be accomplished three times a week for 20 weeks. ...
Happ Mary Beth MB College of Nursing, Ohio State University, Columbus, OH 43210, USA. - - 2013
Despite recognized benefits, many children with cystic fibrosis (CF) do not consistently participate in physical activities. There is little empirical literature regarding the feelings and attitudes of children with CF toward exercise programs, parental roles in exercise, or factors influencing exercise experiences during research participation. The aim of this study ...
Nieman David C - - 2013
This study investigated changes in the human serum metabolome elicited by a 3-day period of intensified training. Runners (N=15, mean±SD age, 35.2±8.7 years) ran for 2.5 h/day on treadmills at ~70% VO2max for 3 days in a row, with blood samples collected pre-exercise, and immediately- and 14 h- post-exercise. Samples ...
Aguiar Aderbal S AS - - 2013
Exercise improves the central nervous system (CNS) functions and is widely recommended for neurological patients with, e.g., Alzheimer's and Parkinson's disease (PD). However, exercise-induced neuroprotection is an open discussion. Here, the intranasal administration of the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP, 65 mg/kg) caused death of dopaminergic neurons in the substantia nigra pars compacta ...
Cannon Daniel T DT Rehabilitation Clinical Trials Center, Division of Respiratory & Critical Care Physiology & Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, - - 2013
The integration of skeletal muscle substrate depletion, metabolite accumulation, and fatigue during large muscle-mass exercise is not well understood. Measurement of intramuscular energy store degradation and metabolite accumulation is confounded by muscle heterogeneity. Therefore, to characterize regional metabolic distribution in the locomotor muscles, we combined 31P magnetic resonance spectroscopy, chemical ...
Sashihara Toshihiro - - 2013
Strenuous exercise reduces immune cell function and increases the risk of respiratory and gastrointestinal infections. In addition, it affects mood state and causes physical fatigue. Athletes require both mental and physical conditioning to execute good performance. In this study, we conducted a randomized, double-blind, placebo-controlled clinical trial to evaluate the ...
Sparks S Andy - - 2013
Aim: To determine the effects of a pre-exercise meal on simulated duathlon time-trial performance. Methods: Nine well trained male participants (age 28.6±5.9 yrs, body mass 77.4±8.2 kg, height 1.81±0.7 m, running VO2peak 4.8±0.5 l·min-1 and cycling VO2peak 4.3±0.6 l·min-1) performed simulated duathlon time trials following three pre-exercise dietary conditions. Participants ...
Zieliński J - - 2013
Purine metabolism reflects the exercise-induced muscle adaptations and training status. This study evaluated the utility of plasma hypoxanthine in the prediction of actual sport performance. We studied male athletes: 28 triathletes (21.4±2.9 years), 12 long-distance runners (23.2±1.9 years), 13 middle-distance runners (22.9±1.8 years) and 18 sprinters (22.0±2.7 years). Season-best race ...
Chidnok Weerapong - - 2013
We tested the hypothesis that muscle high-energy phosphate compounds and metabolites related to the fatigue process would be recovered after exhaustion during recovery exercise performed below but not above critical power (CP) and that these changes would influence the capacity to continue exercise. Eight male subjects completed single-leg knee-extension exercise ...
Peplow Una C - - 2013
ABSTRACT Purpose: The purpose of this study was to explore how parents of children with cerebral palsy, attending mainstream primary schools, perceive the relevance of, and adherence with, exercise programs. Methods: A qualitative research with constructivist approach was used. Semi-structured interviews were conducted with parents. Open-ended questions related to their ...
Shaykhelislamova M V - - 2013
It was found that the response of the adrenal cortex to graded bicycle exercise in children depends on the initial autonomic tonus and is adequate to the background excretion level of hormone metabolites. Seven-year-old sympathotonic girls with increased excretion of 17-hydroxycorticosteroids at rest demonstrated the lowest increase in this parameter ...
Kogan Feliks - - 2013
PURPOSE: To develop a chemical exchange saturation transfer (CEST)-based technique to measure free creatine (Cr) and to validate the technique by measuring the distribution of Cr in muscle with high spatial resolution before and after exercise. METHODS: Phantom studies were performed to determine contributions from other Cr kinase metabolites to ...
Gutierrez-Villanueva J L - - 2013
The last nuclear accident in Fukushima nuclear power plant has increased the necessity for measuring radiation in the environment. Therefore, radiation monitors providing results traceable throughout the country become essential and it is very important to test them under the same environmental conditions. The first intercomparison of natural radioactivity under ...
Pechlivanis Alexandros - - 2012
Metabonomics is an established strategy in the exploration of the effects of various stimuli on the metabolic fingerprint of biofluids. Here we present an application of (1)H NMR-based metabonomics on the field of exercise biochemistry. Fourteen men were assigned to either of two training programs which lasted 8 weeks and ...
Hodgson Adrian B - - 2012
BACKGROUND: Green tea catechins have been hypothesized to increase energy expenditure and fat oxidation by inhibiting catechol-O-methyltransferase (COMT) and thus promoting more sustained adrenergic stimulation. Metabolomics may help to clarify the mechanisms underlying their putative physiological effects. OBJECTIVE: The study investigated the effects of 7-day ingestion of green tea extract ...
Tsay Anthony A Department of Physiology, Monash University, PO Box 13F, Clayton, VIC, 3800, - - 2012
We reported previously that concentric or eccentric exercise can lead to errors in human limb position sense. Our data led us to conclude that the errors, post-exercise, were not due to an altered responsiveness of the proprioceptive afferents, and we proposed that they resulted from central changes in the processing ...
Edge Johann - - 2012
It has been hypothesized that exercise-induced changes in metabolites and ions are crucial in the adaptation of contracting muscle. We tested this hypothesis by comparing adaptations to two different interval-training protocols (differing only in the rest duration between intervals), which provoked different perturbations in muscle metabolites and acid-base status. Prior ...
Crichton Margaret - - 2012
Multi-agency emergency exercises establish and reinforce relationships, and bring people from different areas together to work as a team, realise clear goals, understand roles and responsibilities, and get to know and respect each agency's strengths and weaknesses. However, despite the long-held belief in and respect for exercises in their provision ...
Rathmacher John A - - 2012
Intracellular concentrations of adenosine-5'-triphosphate (ATP) are many times greater than extracellular concentrations (1-10 mM versus 10-100 nM, respectively) and cellular release of ATP is tightly controlled. Transient rises in extracellular ATP and its metabolite adenosine have important signaling roles; and acting through purinergic receptors, can increase blood flow and oxygenation ...
Han Yuan-Yuan - - 2011
Primary thunderclap headache (TCH) is a rare condition, of which the onset can be triggered by coughing, exercise, and sexual activity. Micturition is a recognized trigger of secondary TCH with pheochromocytoma in bladder, but not of primary TCH. We describe a patient with an apparent primary TCH, which repeatedly occurred ...
Thomson R L - - 2011
Polycystic ovary syndrome (PCOS) is characterized by the presence of polycystic ovaries, menstrual dysfunction, infertility and biochemical and clinical hyperandrogenism and is associated with an increased prevalence of cardiometabolic risk factors and psychological problems. Despite the well-established benefits of exercise training and its recommendation as a cornerstone of PCOS management, ...
Lenz Thomas L - - 2011
Transdermal drug delivery systems, such as the transdermal patch, continue to be a popular and convenient way to administer medications. There are currently several medications that use a transdermal patch drug delivery system. This article describes the potential untoward side effects of increased drug absorption through the use of a ...
Maddocks Matthew - - 2011
Objective: Therapeutic exercise may benefit patients with incurable cancer, but there is little data on its practicality. We have explored the acceptability of six exercise programmes based on different types of exercise, the preferred delivery method, location and time relative to anticancer treatments and whether various patient characteristics influence choice ...
Østerås Håvard - - 2010
Exercise therapy is a commonly used conservative therapy for long-term subacromial pain. However, there is no consensus regarding what type of exercises and dosage is most effective. The aim of this study was to compare the effect of two exercise programmes: 1) high-dosage (HD) medical exercise therapy versus 2) low-dosage ...
Keramidas Michail E - - 2011
The purpose of the study was to investigate the effect of 30-min voluntary hyperpnoea on cerebral, respiratory and leg muscle balance between O(2) delivery and utilization during a subsequent constant-power test. Eight males performed a V˙O(2max) test, and two exercise tests at 85% of peak power output: (a) a control ...
Perry Jo - - 2011
Two commonly utilised manual therapy techniques; McKenzie's lumbar extension exercises (EE); and segmental rotational grade V manipulation were investigated to determine their magnitude of neurophysiological effect. Proxy measures of sympathetic nervous system (SNS) activity (skin conductance) were utilised to ascertaining neurophysiological response. This study determined the neurological effects of these ...
Silbernagel Karin Grävare - - 2011
Systematic reviews indicate that exercise has the most evidence of effectiveness in treatment of midportion Achilles tendinopathy. However, there is a lack of long-term follow-ups (>4 years). To evaluate the 5-year outcome of patients treated with exercise alone and to examine if certain characteristics, such as level of kinesiophobia, age, ...
Valkenet Karin - - 2011
To summarize the current evidence on the effects of preoperative exercise therapy in patients awaiting invasive surgery on postoperative complication rate and length of hospital stay. Data sources: A primary search of relevant key terms was conducted in the electronic databases of PubMed, EMBASE, PEDro and CINAHL. Review methods: Studies ...
Zunker Christie - - 2010
OBJECTIVE:: To identify exercise interventions in the empirical literature to help inform clinical decision making in the treatment of underweight individuals with anorexia nervosa (AN) and review any recommended differences in treatment planning for those who excessively exercise and those who do not. METHOD:: Online search engines and cross-referencing articles ...
Mackenzie Catherine - - 2010
Non-speech oro-motor exercises (NSOMExs) are described in speech and language therapy manuals and are thought to be much used in acquired dysarthria intervention, though there is no robust evidence of an influence on speech outcome. Opinions differ as to whether, and for which dysarthria presentations, NSOMExs are appropriate. The investigation ...
Kucyi Aaron - - 2010
Neurocognitive dysfunction associated with bipolar disorder (BD) is pervasive, persistent across illness phases, and is demonstrated to predispose and portend psychosocial impairment. Moreover, no approved therapies for various phases of BD have been shown to reliably improve any dimension of neurocognitive performance. In this article, we emphasize that aerobic physical ...
Wright Jennifer L - - 2010
Adult guardianship is a coercive exercise of the state's power over an innocent individual, justified only by: 1) the ward's incapacity; and 2) the need to protect the ward's well-being. The raison d'être of guardianship is to improve the well-being of the incapacitated ward. Studies of actual guardianship proceedings have ...
Cunali Paulo Afonso - - 2011
Temporomandibular disorder (TMD) has been the most common contraindication for mandibular advancement device (MAD) as a treatment for obstructive sleep apnea syndrome (OSAS). Exercising the mandible is a recommended form of therapy for TMD. To assess the efficacy of mandibular exercises in the control of pain, changes of quality of ...
Krogh Jesper J Psychiatric Center Bispebjerg, Bispebjerg University Hospital, DK-2400, Denmark. - - 2011
To assess the effectiveness of exercise in adults with clinical depression. The databases CINAHL, Embase, Cochrane Database of Systematic reviews, Cochrane Controlled Trials Register, MEDLINE, and PsycINFO were searched (1806-2008) using medical subject headings (MeSH) and text word terms depression, depressive disorder and exercise, aerobic, non-aerobic, physical activity, physical fitness, ...
Hassani Adam A Mitochondrial Research Group, Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, - - 2010
Treatment options for mitochondrial myopathies remain limited despite rapid advances in the understanding of the molecular basis of these conditions. Existing therapies continue to be evaluated and novel treatment strategies are starting to appear on the horizon. Exercise training continues to show promise as a method of improving exercise tolerance ...
Weber Mary - - 2010
This article reviews the use of exercise as a therapeutic and adjunctive intervention in the prevention of weight gain, obesity, and metabolic consequences in multiple populations with psychiatric illnesses. The purpose was to identify the current state of the science for the use of exercise as a psychiatric nursing intervention, ...
Shahidi Mahvash - - 2011
Laughter Yoga founded by M. Kataria is a combination of unconditioned laughter and yogic breathing. Its effect on mental and physical aspects of healthy individuals was shown to be beneficial. The objective of this study was to compare the effectiveness of Kataria's Laughter Yoga and group exercise therapy in decreasing ...
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