Proper treatment for osteoarthritis will help control pain and other symptoms, and let you live a more vigorous, satisfying life. Exercise is a vital part of osteoarthritis treatment: It's a scientifically proven way for you to help yourself. The right kind of exercise will benefit the joints that have been ...

OBJECTIVE: To test the efficacy of a graded aerobic exercise programme in the chronic fatigue syndrome. DESIGN: Randomised controlled trial with control treatment crossover after the first follow up examination. SETTING: Chronic fatigue clinic in a general hospital department of psychiatry. SUBJECTS: 66 patients with the chronic fatigue syndrome who ...

Although patients with chronic illnesses typically refrain from exercise, many of them could benefit significantly from mild, long-term exercise therapy. While factors such as pain or weakness often discourage the chronically ill person from being physically active, lack of motivation and lack of knowledge are the primary obstacles. An effective ...

OBJECTIVE: To assess the efficacy of estrogen antagonist therapy on the function of the hypothalamic-pituitary-testicular axis in a young male runner with significant morbidity attributable to idiopathic hypogonadotropic hypogonadism. DESIGN: An uncontrolled case study. SETTING: The outpatient endocrinology clinic of a university tertiary referral center. PATIENT(S): A 29-year-old male who ...

F-wave amplitudes have been used to demonstrate changes of motor neuron excitability in patients receiving pharmacological antispastic therapy as well as in those having physiotherapy. In this study it is shown that F-wave amplitudes can also be used to document changes of motor neuron excitability as an effect of the ...

Therapeutic mechanisms hypothesized to underlie improvements in tension headache activity achieved with combined relaxation and electromyographic (EMG) biofeedback therapy were examined. These therapeutic mechanisms included (1) changes in EMG activity in frontal and trapezii muscles, (2) changes in central pain modulation as indexed by the duration of the second exteroceptive ...

We conducted a randomized, controlled study in southern Colombia to determine if the addition of allopurinol to stibogluconate was superior to stibogluconate alone in the treatment of cutaneous leishmaniasis. Lesions that healed after a 3-month course of therapy and remained so during a 1-year period of follow-up were considered cured. ...

Substance abuse treatments are increasingly employing standardized formats. This is especially the case for approaches that utilize an individual psychotherapy format but less so for family-based approaches. Network therapy, an approach that involves family members and peers in the patient's relapse prevention efforts, is theoretically and clinically differentiated in this ...

Benign paroxysmal positional vertigo (BPPV) is a common condition that often resolves spontaneously, but can cause significant distress to a patient. Management of this condition includes no intervention, medication, surgery, physical exercises and more recently 'particle repositioning' manoeuvres. Repositioning manoeuvres aim to relocate free-floating particles from the posterior semicircular canal ...

Although a number of experimental investigations into the effects of hemisphere stimulation on the reading performance of individuals with dyslexia are currently available, only a few studies have addressed the effects of treatment in the setting of an outpatient clinic. The present study reports on the reading results after a ...

We reevaluate here the effects of chronic administration of levodopa on its peripheral pharmacokinetics and the contribution of the pharmacokinetics to the pathogenesis of the wearing-off phenomenon. The peak levodopa concentration (Cmax) and the area under the time-concentration curve (AUC) were markedly increased after long-term levodopa therapy, whereas the time ...

We report a short-term double-blind, crossover study of CoQ10 in 8 patients with mitochondrial encephalomyopathies. Four patients had myoclonus epilepsy with ragged-red fibers syndrome, 3 had mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes syndrome, and 1 had chronic progressive external ophthalmoplegia with myopathy. A trend of effectiveness of CoQ10 ...

Twenty-four postgraduate-trained sports physiotherapists were interviewed to investigate their experiences with exercise dependent patients. The respondents identified exercise dependent patients as likely to continue physical activity when injured. They were described in terms such as anxious, obsessive, overachieving and addicted to feelings. The majority of physiotherapists (71 per cent) reported ...

For the cerebral palsy patient undergoing botulinum toxin (BTX) therapy, the physical therapist is involved in each step of treatment, from patient selection to outcome assessment. Prior to treatment, the therapist collects detailed baseline information, including assessment of motor ability, functional activities, current therapies and assistive devices, and the concerns ...

Brief dynamic psychotherapy, carried out by an resident in training, can bring significant improvement to a patient who does not necessarily meet ideal selection criteria. S. had experienced early childhood deprivation resulting in adult psychosomatic manifestations of feeling hypoglycemic under pressure of responsibility or during fear of abandonment. He soothed ...

The objective of this study was to assess, via heart rate, the arousal levels of participants in group trauma reexposure therapy for posttraumatic stress disorder, and so to better understand this common mode of treatment, particularly in regards to its presumed curative factor, extinction. Six Vietnam combat-related PTSD inpatients participated ...

Physical and occupational therapists play important roles in the evaluation and management of patients receiving botulinum toxin injections for spasticity. Baseline evaluation includes areas beyond the muscles being injected, since local spasticity reduction may lead to more widespread functional changes. Because the evaluation itself influences tone, a consistent order of ...

Although regarded as a benign condition, simple hypertrichosis may be very disturbing to a child cosmetically. An abnormality in androgen metabolism has been implied in the etiology of simple hypertrichosis recently. This study was undertaken to investigate the effect of spironolactone therapy for its antiandrogenic property in 12 prepubertal girls ...

Carbon monoxide (CO) poisoning is a common medical emergency and a frequent cause of deliberate or accidental death. It can cause acute and chronic central nervous system damage which may be minimised by prompt treatment with 100% oxygen or hyperbaric oxygen therapy. However, recognition of this intoxication can be difficult. ...

Early intervention and attention to nutritional status are essential in patients with cachexia. Identification of reversible causes of decreased energy intake and/or weight loss is the first step in treatment. When such factors cannot be identified, pharmacologic interventions should be considered. To date, megestrol acetate is the most effective appetite ...

OBJECTIVE: Our purpose was to test whether estrogen replacement therapy could increase exercise tolerance in postmenopausal women. STUDY DESIGN: A randomized, double-blind, placebo-controlled, crossover study in 31 healthy postmenopausal women who received 12 weeks of physiologic estrogen replacement therapy (micronized estradiol, 2 mg/day) and were evaluated with modified Balke exercise ...

Chronic compartment syndrome (CCS) is a possible explanation of leg pain in the exercising patient. This review article provides background information on CCS, focusing on its most frequent site of occurrence, i.e., the lower leg. Clinical history, diagnosis, compartmental tissue pressure measurement, conservative therapy, surgical intervention, postoperative nursing care and ...

As midwives increasingly provide care to women throughout the lifecycle, they need to become familiar with a variety of treatments for perimenopausal and postmenopausal problems and preventive measures for the potentially disabling conditions that can accompany aging. This article reviews various regimens of hormone replacement therapy. It discusses types of ...

The mutation in X-linked bulbospinal muscular atrophy (XBSMA) is an increased CAG triplet repeat coding for a polyglutamine domain in the gene for the androgen receptor. This might impair the effect of testosterone on motor neurons, leading to their progressive degeneration. We report a trial of high-dose oral testosterone therapy ...

Byng (1988) has argued that some aphasic patients who show problems in sentence comprehension are unable to "map" a syntactic analysis of the sentence form onto the thematic roles specified by the verb or preposition in the sentence. In Byng's study, therapy aimed at improving the mapping process as applied ...

The need for a peritoneal dialysis modality capable of providing higher clearances of small solutes at a competitive cost with continuous ambulatory peritoneal dialysis (CAPD) has been identified. A new modality of therapy (PD Plus; Fresenius USA, Walnut Creek, CA), which is based on the principles of optimal dwell time ...

Botulinum toxin (BTX) is the treatment of choice for blepharospasm. To investigate if the locally injected BTX influences the central nervous system and in particular the brain stem, amplitude and latency of compound muscle action potential (CMAP) of orbicularis oculi, blink reflex and brain stem auditory evoked potential were studied ...

Recombinant human DNase I, or dornase alfa, is the first new therapy developed specifically for cystic fibrosis in almost 30 years. It selectively digests extracellular DNA and reduces the viscosity of purulent sputum. In clinical trials dornase alfa modestly improved pulmonary function, slightly decreasing the number of respiratory exacerbations requiring ...

The antihypertensive treatments have resulted in favorable effects in terms of cardiovascular morbidity and mortality in the elderly, but the therapeutic approaches raise problems linked to the pathophysiological aspects of hypertensives and to the reduced homoeostatic capacity of the senile organism. The antihypertensive treatment in elderly must be aimed at ...

The range of complementary therapies available has increased. The treatments offered may improve the 'whole' person but not the 'part' which is diseased. Inquiry into the length and type of training of therapists is needed to ensure ethical practice. Recognition of the usefulness of some complementary therapies by orthodox medical ...

A 25-year-old woman with a specific phobia related to vaginal penetration fears was effectively treated with graduated exposure therapy involving self-conducted and partner-assisted homework exercises. Treatment produced a complete resolution of the problem within 12 sessions. This behavior therapy regimen followed the client having received several periods of psychodynamic therapy ...

This study investigated the effectiveness of oral myofunctional therapy in eliminating a 16 year-old girl's tongue thrust swallowing pattern and mild sibilant distortion. An ABC design was used where Phase A had eight baseline sessions (no treatment), Phase B had 14 oral myofunctional therapy sessions, and Phase C had four ...

There appears to be a pendulum swing toward large epidemiologic studies questioning the role of occlusion in dentistry. This article clearly demonstrates that significant scientific evidence exists on the side of occlusal causative factors. Clinicians need this current information to base practical decisions of treatment relative to both patients and ...

OBJECTIVE: To describe a patient with cyclic vomiting who was treated successfully with sumatriptan, a serotonin, agonist. CASE SUMMARY: A patient with a 4-year history of cyclic vomiting was treated for an episode of nausea, vomiting, and abdominal pain. This patient had been hospitalized numerous times for cyclic vomiting over ...

Although Tianrong acupoint (SI 17) is used for migraine headache, its mechanism of action remains obscure. The effects of Tianrong acupoint therapy on neurogenically-mediated plasma protein extravasation (125I-BSA) in rat dura mater induced by electrical stimulation of the right trigeminal ganglion was studied. When the unilateral trigeminal ganglion was stimulated ...

The aim of the study was to assess the value of quantitative attenuation values (Hounsfield units) and of gallstone pattern by computerized tomography in predicting response to bile acid therapy. We carried out a prospective study in a multicenter setting on 90 consecutive outpatients with radiolucent gallstones. All received bile ...

This article investigated the mechanisms underlying associations between patients' contribution to the alliance and outcome by examining relations between change in the alliance over the course of treatment and improvement in Short-Term Dynamic Psychotherapy (STDP) and Brief Adaptive Psychotherapy (BAP). Findings for STDP were consistent with 1 model about the ...

Following presentation and diagnosis, microprolactinomas usually follow a benign course and rarely progress to macroprolactinomas. However, clinically significant enlargement of prolactinomas during pregnancy, presumably related to estrogen stimulation, has been reported. This report describes a patient with amenorrhea and hyperprolactinemia and a microadenoma by computed tomography scan who developed a ...

The provision of options in the occupational form that encourages meaningful choices and subsequent purposeful occupational performances is a basic premise of occupational therapy. This study examines the preferences of elderly nursing home residents when presented with an occupationally embedded exercise versus a rote exercise and addresses the methodological problems ...

Many patients who are referred for physical therapy take medications that affect either their physiological responses to exercise or their ability to exercise. The purpose of this article is to discuss how medications potentially can affect cardiovascular responses to exercise. The effects of selected medications on heart rate, blood pressure, ...

Recombinant bovine interleukin-2 was tested as adjunct therapy to intramammary infusion of antibiotics at drying off. Cows were assigned randomly within three commercial herds to either recombinant bovine interleukin-2 or PBS treatment groups at drying off. Ninety-five cows received intramammary infusions of 1 mg of recombinant bovine interleukin-2 in each ...

Cost-effectiveness analysis of preventive therapies are reviewed in the following categories: lipid lowering, hypertension, smoking cessation, exercise, and anticoagulation. From review of 8 analyses, cost-effectiveness of primary prevention via cholesterol lowering drugs is generally expensive, whereas that of secondary prevention generally is favorable. However, targeting by age, coexisting risk factors, ...

Eight currently underused therapeutic regimens are reviewed on the basis of their potential to have a major impact on morbidity and mortality in adults. The criteria for the selection of these regimens included their safety, effectiveness and cost-effectiveness, the availability of substantial data to support their efficacy, and the existence ...

The keys to differential diagnoses and anatomical localization for causes of acute respiratory distress are based on history and physical examination findings. The specific factors and therapeutic considerations for conditions associated with acute respiratory distress ranging from laryngeal paralysis to diaphragmatic hernia are examined. Additionally, the general approaches and principles ...

We studied the in vivo effect of long-term doxycycline treatment combined with NSAID on human interstitial collagenases, other matrix metalloproteinases, serine proteinases, tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) and lactoferrin from saliva and serum during the course of acute reactive arthritis (ReA). Collagenase activity and serine proteases (elastase-like, cathepsin G-like ...

Fifteen subjects with upper extremity work-related cumulative trauma disorders were involved in a quality improvement study to determine their self-reported degree of follow-through with reinjury prevention regimens. The effect of cuing was also studied. During occupational therapy, subjects were involved in an educational session that focused on recommendations in ergonomic ...

The objective of this study was to report on a breakthrough of Plasmodium falciparum infection following a military exercise in central Kenya and the treatment regimens used. A series of case reports are presented from the three UK hospitals involved. Among 150 British soldiers who had been on exercises for ...

Noninvasive complex lymphedema therapy (CLT), a technique of manual lymph drainage, compressive bandaging, and specific physical therapy exercises, has been utilized successfully to treat lymphedema in Europe and Australia. This paper reports the results of such therapy in 38 patients (16 females with arm lymphedema secondary to breast surgery, 18 ...

PURPOSE: To review the efficacy of nonmedicinal, noninvasive therapies in hip and knee osteoarthritis. DATA SOURCES: Search of English-language literature from 1966 through 1993 using MEDLINE by cross-referencing "osteoarthritis" (therapy subheadings) with "controlled trial," "comparative study," or "trial(s)." STUDY SELECTION: Fifteen controlled trials of diathermy (deep heat), exercise, acupuncture, transcutaneous ...

Exercise capacity in patients with kidney failure undergoing dialysis is low compared with age-predicted values. The level of exercise tolerance in these patients is such that the energy requirements for activities of daily living and occupational tasks impinge on their capacity to perform these tasks. Therefore, it is not surprising ...