Search Results
Results 501 - 550 of 1219
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Steiger Dominik - - 2008
Myc proteins are powerful proto-oncoproteins and important promoters of growth and proliferation during normal development. They are thought to exercise their effects upon binding to their partner protein Max, and their activities are largely antagonized by complexes of Max with Mnt or an Mxd family protein. Although the biological functions ...
Pinet Bernard M - - 2008
The main purpose of this study was to evaluate the relationship between different methods proposed by the American College of Sports Medicine (ACSM) to prescribe exercise intensity using heart rate (HR) and oxygen uptake (VO2) in obese individuals. Sixty-eight overweight to severely obese adults were divided into three groups (tertile) ...
Murray James A - - 2009
BACKGROUND: Although the cycle ergometer is the traditional mode for exercise testing in patients with respiratory disease, this preference over the treadmill does not consider perceptual responses. Our hypotheses were as follows: (1) the regression slope between breathlessness and oxygen consumption (Vo(2)) is greater on the treadmill than on the ...
Wang Eivind - - 2008
This study examined whether a training intervention likely to elicit adaptations in the leg could result in reduced leg pain and increased whole body physical capacity. Twenty-seven peripheral arterial disease (PAD) patients were randomized to either an individual leg plantar flexion training group (TG) training 4 x 4 min intervals ...
Cintra Fatima - - 2009
BACKGROUND: OSA severity has been associated with self-reported lack of exercise. Most of the research has been done with men recruited from sleep clinics. There is limited data on the exercise performance of women with OSA. Therefore, the aim of this study was to assess exercise performance in a prospective, ...
Honold Joerg - - 2008
BACKGROUND: Detecting heart failure (HF) patients at risk is a relevant clinical problem. Our goal was to define associations of clinical HF-markers and exercise parameters with respect to their prognostic power in HF-patients. METHODS: We performed cardiopulmonary exercise testing (CPET) in 103 ischemic HF-patients. CPET-parameters included peak VO(2), VO(2) at ...
Agostoni Piergiuseppe - - 2008
AIMS: The influence of permanent atrial fibrillation on exercise tolerance and cardio-respiratory function during exercise in heart failure (HF) is unknown. METHODS AND RESULTS: We retrospectively compared the results of 942 cardiopulmonary exercise tests, performed consecutively at seven Italian laboratories, in HF patients with atrial fibrillation (n = 180) and ...
Demura Shinichi - - 2008
This study was done to examine the influence of instructions on the evaluation of rhythmic repeated muscular endurance, that is, the ability to continue muscle-power exertion at a regular interval. 15 healthy young male adults performed maximal repeated rhythmic grips for 6 min. under the following three instruction conditions: (1) ...
Patrick Neary J - - 2008
This study examined the effects of maximal incremental exercise on cerebral oxygenation in chronic fatigue syndrome (CFS) subjects. Furthermore, we tested the hypothesis that CFS subjects have a reduced oxygen delivery to the brain during exercise. Six female CFS and eight control (CON) subjects (similar in height, weight, body mass ...
Kemps Hareld M - - 2008
The purpose of this study was to investigate which patient characteristics may predict training effects on maximal and submaximal exercise performance in patients with heart failure. Together with commonly used clinical and performance-related variables, oxygen uptake kinetics during exercise recovery were included as possible predictors. Fifty patients with heart failure ...
Hoshimoto-Iwamoto Masayo - - 2008
Incremental exercise testing to a symptom-limited maximum has been used to measure the ratio of the increase in ventilation (V.E) to the increase in CO(2) output (V.CO(2)) during exercise (V.E/V.CO(2) slope), a valuable index reflecting the severity of the ventilation-perfusion mismatch in heart failure. Here we studied whether this same ...
De Groot J F - - 2008
The objective of this study is to interpret the outcomes of peak oxygen uptake (VO(2peak)) in children with SB and explore the relationship between VO(2peak) and functional ambulation using retrospective cross-sectional study. Twenty-three ambulating children with SB participated at Wilhelmina's Children's Hospital Utrecht, the Netherlands. VO(2peak) was measured during a ...
Meadows Jeffery - - 2008
OBJECTIVES: The aim of this study was to prospectively examine the effects of elective Fontan fenestration closure upon exercise capacity and ventilatory abnormalities. BACKGROUND: For patients undergoing Fontan procedures as palliation of single ventricle physiology, the addition of a fenestration to the procedure mitigates perioperative morbidity. Although some fenestrations may ...
Paridon Stephen M - - 2008
OBJECTIVES: The aim of this study was to describe exercise performance during the first 2 decades of life in Fontan survivors by a cross-sectional study and to identify factors that influence exercise performance. BACKGROUND: Exercise performance after the Fontan procedure is reduced relative to performance in healthy subjects. Data on ...
Morrison Elizabeth H - - 2008
OBJECTIVE: To compare ratings of perceived exertion (RPEs) during aerobic exercise in people with multiple sclerosis (MS) and control participants. DESIGN: Prospective experimental study. SETTING: An exercise testing laboratory. PARTICIPANTS: Sedentary adults (n=12) with mild MS (Expanded Disability Status Scale score < or = 3) aged 30 to 45 years ...
Smits Jasper A J - - 2009
The present study examined the effects of acute exercise on anxiogenic responding to 65% O(2)/35% CO(2) challenge. Participants (N=92) were 51 female and 41 male volunteers ranging in age from 17 to 24 (M=19.43, SD=1.31). Participants had no history of panic attacks and were randomized to moderate treadmill exercise (i.e., ...
Mays Wayne A - - 2008
This study evaluated the aerobic capacity, exercise capacity, and arterial oxygen saturation (O(2)Sat) in children before and after transcatheter Fontan fenestration closure. Observational study comparing exercise parameters and hemodynamics before and after transcatheter fenestration closure in Fontan patients. Working capacity, exercise duration, oxygen consumption (VO(2)), and arterial O(2)Sat were evaluated ...
Ababneh Zaid Q - - 2008
PURPOSE: To assess the transverse relaxation time T(2) and diffusion coefficient D before and following exercise in the tibialis anterior muscle and determine whether T(2) and D values were correlated. METHODS: Measurements of T(2) and D were performed at 3 T within axial slices through the calf muscles of six ...
Inbar Omri - - 2008
The purpose was to study the effect of endoscopic thoracic sympathectomy (ETS) for palmar and/or axillary hyperhidrosis on physiological responses at rest, and during sub-maximal and maximal exercise in ten healthy patients (7 females and 3 males 18-40 years old) with idiopathic palmar and/or axillary hyperhidrosis. T2-T3 thoracoscopic sympathectomy was ...
Giardini Alessandro - - 2008
AIMS: We sought to assess the effects of sildenafil on exercise capacity and haemodynamic response to exercise in Fontan patients. METHODS AND RESULTS: We prospectively studied 27 patients with Fontan circulation (age 22.8 +/- 4.9 years). All patients underwent a baseline exercise test with non-invasive measurement of cardiac index (CI) ...
Sørensen J B - - 2008
The aim of this study was to compare short- (0-4 months) and long-term (0-10 months) effects of high-intensive Exercise on Prescription (EoP) intervention (counseling and supervised exercise) implemented in primary healthcare in a number of Danish counties with a low-intensive intervention (counseling) using maximal oxygen uptake (VO(2max)) as the primary ...
Conti A - - 2008
AIM: The aim of this study was to assess maximal cardiac and metabolic demand imposed by in place shallow water running (SWR) and to compare such responses with those obtained during treadmill running (TMR). METHODS: Twelve males, 6 trained (T) pentathletes (age: 19+/-1 years) and 6 untrained (UT) controls (age: ...
Segerström Asa B - - 2008
The primary aim of this study was to compare the maximal oxygen uptake as evaluated from a submaximal exercise test (EVO2peak) to direct measurements of VO2peak during a maximal exercise test as means of monitoring the aerobic endurance capacity in women with type 2 diabetes (T2D). Twenty-seven women with T2D ...
Merson Stuart J - - 2008
To investigate how differing moderate sodium chloride concentrations affect rehydration after exercise and subsequent exercise capacity, eight males lost 1.98 +/- 0.1% body mass exercising in the heat, then consumed one of four drinks in a volume equivalent to 150% of mass loss. Drinks were identical except for sodium chloride ...
Neumann J-O - - 2008
To assess the use of hyperventilation and the adherence to Brain Trauma Foundation-Guidelines (BTF-G) after traumatic brain injury (TBI). Twenty-two European centers are participating in the BrainIT initiative. Retrospective analysis of monitoring data. One hundred and fifty-one patients with a known time of trauma and at least one recorded arterial ...
Tahara Yasuaki - - 2008
The relationship between fat-free mass (FFM) and excess post-exercise oxygen consumption (EPOC) has not been well researched because of the relatively small number of subjects studied. This study investigated the effects of FFM on EPOC and EPOC/maximum oxygen consumption. 250 Japanese male athletes between 16 and 21 years old from ...
Mukai Kazutaka - - 2008
OBJECTIVE: To determine whether warm-up exercise at different intensities alters kinetics and total contribution of aerobic power to total metabolic power in subsequent supramaximal exercise in horses. ANIMALS: 11 horses. PROCEDURES: Horses ran at a sprint until fatigued at 115% of maximal oxygen consumption rate (VO(2max)), beginning at 10 minutes ...
Lamprecht Manfred - - 2008
The purpose of this study was to investigate the effect of single bouts of exercise at three different intensities on the redox state of human serum albumin (HSA) and on carbonyl groups on protein (CP) concentrations in plasma. Trained men [n = 44, maximal oxygen consumption (Vo(2max)): 55 +/- 5 ...
Houghton Kristin M - - 2008
OBJECTIVE: To measure aerobic fitness (maximum oxygen consumption [VO(2peak)]), fatigue, quality of life (QOL), and disease activity in young persons with systemic lupus erythematosus (SLE), and to determine an equation for predicting VO(2peak) from the distance walked in 6 minutes (6MW). METHODS: Fifteen young patients ages 12-19 years with SLE ...
Kubozono Takuro - - 2008
BACKGROUND: It is well-known that both B-type natriuretic peptide (BNP) and peak oxygen uptake (VO(2)) are independent predictors of mortality in patients with heart failure. This study investigates the predictive power of BNP and peak VO(2) for survival in cardiac patients. METHODS AND RESULTS: A total of 609 patients with ...
Zoladz J A - - 2009
In this study we have evaluated the effect of maximal incremental cycling exercise (IE) on the systemic release of prostacyclin (PGI(2)), assessed as plasma 6-keto-PGF(1alpha) concentration in young healthy men. Eleven physically active - untrained men (mean +/- S.D.) aged 22.7 +/- 2.1 years; body mass 76.3 +/- 9.1 kg; ...
Chiappa Gaspar R - - 2008
Patients with chronic obstructive pulmonary disease (COPD) have slowed pulmonary O(2) uptake (Vo(2)(p)) kinetics during exercise, which may stem from inadequate muscle O(2) delivery. However, it is currently unknown how COPD impacts the dynamic relationship between systemic and microvascular O(2) delivery to uptake during exercise. We tested the hypothesis that, ...
Kampus Priit - - 2008
Regular aerobic training has beneficial effects on inflammatory pathways and on arterial elasticity, which are both important cardiovascular risk factors. The aim of the present study was to evaluate the effect of extreme physical load on arterial elasticity and inflammatory markers in well-trained healthy men who participated in a high-ranking ...
Guidetti Laura - - 2008
This study evaluated energy cost and energy sources of a ballet exercise (grand adage) in young female dancers with different technical ability, and then related the energy sources to the subject's VO(2max) and anaerobic threshold (IAT). Twenty-five dancers (13-16 years) were divided into two different technical ability groups: low-level (n ...
Goosey-Tolfrey Victoria L - - 2008
The aims of this study were two-fold: (1) to consider the criterion-related validity of the multi-stage fitness test (MSFT) by comparing the predicted maximal oxygen uptake (.VO(2max)) and distance travelled with peak oxygen uptake (VO(2peak)) measured using a wheelchair ergometer (n = 24); and (2) to assess the reliability of ...
Maxwell Mark S - - 2008
BACKGROUND: Cardiorespiratory fitness level is inversely related to the incidence of Metabolic Syndrome (MetS). This study examined the effects of changes in cardiorespiratory fitness level on MetS status. METHODS: Male and female participants in a health enhancement program (n = 212) were clinically examined for changes in their MetS status ...
Giardini Alessandro - - 2008
BACKGROUND: Previous studies have shown that older Fontan patients and those with an underlying morphologically right ventricle have lower exercise capacity. We sought to assess the natural history of exercise capacity after the Fontan operation in individual patients, and to identify the factors influencing the rate of decrease of exercise ...
Davies R C - - 2008
The purpose of this study was to assess whether maximal oxygen uptake (V.O(2 max)) could be predicted from submaximal ratings of perceived exertion (RPE) elicited during the multistage fitness test (MFT). Eleven female volunteers completed three maximal exercise tests in random order; the MFT, a simulated MFT on a motorized ...
Nanas S - - 2009
The purpose of our study was assessment of the relative contribution of the systems involved in blood gas exchange to the limited exercise capacity in patients with beta-thalassemia major (TM) using integrative cardiopulmonary exercise testing (CPET) with estimation of oxygen kinetics. The study consisted of 15 consecutive TM patients and ...
Daussin Frédéric N - - 2008
This study explored mitochondrial capacities to oxidize carbohydrate and fatty acids and functional optimization of mitochondrial respiratory chain complexes in athletes who regularly train at high exercise intensity (ATH, n = 7) compared with sedentary (SED, n = 7). Peak O(2) uptake (Vo(2max)) was measured, and muscle biopsies of vastus ...
Terziyski K - - 2008
1. The impact of ventilatory efficiency on reduced exercise capacity and recovery oxygen kinetics has not been addressed in cirrhotic patients. The aim of the present study was to investigate exercise performance and ventilatory efficiency in patients with mild and moderate liver cirrhosis (LC). 2. Nineteen male non-hypoxic patients with ...
Ingham Stephen A - - 2008
PURPOSE: To identify the optimal aerobic determinants of elite, middle-distance running (MDR) performance, using proportional allometric models. METHODS: Sixty-two national and international male and female 800-m and 1500-m runners undertook an incremental exercise test to volitional exhaustion. Mean submaximal running economy (ECON), speed at lactate threshold (speedLT), maximum oxygen uptake ...
Arena Ross - - 2008
There does not appear to be a relationship between peak oxygen consumption (VO(2)) and body mass index (BMI) in patients with heart failure (HF). We assessed the hypothesis that BMI and the oxygen uptake efficiency slope (OUES) would be related. Three hundred and thirty-seven HF patients (280 male/57 female, mean ...
Harris Ryan A - - 2008
OBJECTIVE: Inflammation has been found to play a role in the etiology of cardiovascular disease as well as provoke endothelial dysfunction. Inflammatory cytokines associated with endothelial function are interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha). IL-6 is exercise intensity dependent and has been shown to inhibit TNF-alpha expression directly. The ...
Barker Alan R - - 2008
To further understand the mechanism(s) explaining the faster pulmonary oxygen uptake (p(VO)(2)) kinetics found in children compared to adults, this study examined whether the phase II p(VO)(2) kinetics in children are mechanistically linked to the dynamics of intramuscular PCr, which is known to play a principal role in controlling mitochondrial ...
Fujii Naoto - - 2008
We tested the hypothesis that, in humans, hyperthermic hyperpnea elicited in resting subjects differs from that elicited during submaximal, moderate-intensity exercise. In the rest trial, hot-water legs-only immersion and a water-perfused suit were used to increase esophageal temperature (T(es)) in 19 healthy male subjects; in the exercise trial, T(es) was ...
Stensrud T - - 2008
INTRODUCTION: Several different exercise protocols are used to assess exercise-induced bronchoconstriction (EIB), and to measure peak oxygen uptake (VO(2 peak)) and peak minute ventilation (VE(peak)). OBJECTIVE: The aim of this study was to evaluate if one single test protocol for assessing EIB can also be used to determine aerobic capacity ...
Bhaumik Gopinath - - 2008
OBJECTIVE: Maximum aerobic capacity decreases at high altitude. This study was conducted to compare the changes in maximum aerobic capacity in men and women mountaineering trainees on induction to high altitude at 4350 m by trekking. METHODS: Eight men and 8 women mountaineering trainees in a mountaineering course were selected ...
Koegelenberg Coenraad F N - - 2008
BACKGROUND: Algorithms for the pre-operative evaluation of lung resection candidates with impaired lung function invariably include maximum oxygen uptake (VO(2)MAX) as a critical parameter of functional reserves, with a VO(2)MAX >or=20 ml/kg/min generally considered sufficient for pneumonectomy. Stair climbing is a low-cost alternative to assess exercise capacity. OBJECTIVES: As stair ...
Robach Paul - - 2008
Treatment with recombinant human erythropoietin (rhEpo) induces a rise in blood oxygen-carrying capacity (CaO(2)) that unequivocally enhances maximal oxygen uptake (VO(2)max) during exercise in normoxia, but not when exercise is carried out in severe acute hypoxia. This implies that there should be a threshold altitude at which VO(2)max is less ...
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