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Results 251 - 300 of 928
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Gamradt Seth C - - 2010
BACKGROUND: There has been limited in-vivo assessment of rotator cuff vascularity following repair. This study aims to characterize the vascularity of the shoulder 3 months following supraspinatus tendon repair. METHODS: Twenty-nine patients (average age, 61.4 years) underwent Perflutren lipid microsphere contrast-enhanced shoulder ultrasound examinations 3 months after arthroscopic rotator cuff ...
Chandra Ananga Mohan - - 2010
Visual and auditory simple reaction times for both right and left hands of young university male students were recorded with a simple reaction timer, before and after an exercise schedule without and with elevated temperatures in a climatic chamber. The results indicated a decrease in both visual and auditory reaction ...
Cotofana S - - 2010
Epidemiological studies show a positive relationship between physical activity and cartilage volume, suggesting that exercise may protect against osteoarthritis. Cross-sectional experimental studies, however, have failed to show significant differences in knee cartilage morphology between athletes and nonathletic controls. The aim of the study was to test the hypothesis that knee ...
O'Konski Marjorie - - 2010
The current study compared exercise performance and participant satisfaction for 2 conditions: Patterned Sensory Enhanced music (PSE) and big band background music. Residents of long-term care facilities in the Midwest (N = 45) attended a minimum of 3 sessions per condition and reported levels of satisfaction after each session. Observers ...
Tranquille Carolyne A - - 2009
OBJECTIVE-To investigate effects of exercise on hyaline cartilage (HC), calcified cartilage (CC), and subchondral bone (SCB) thickness patterns of equine tarsi. SAMPLE POPULATION-30 tarsi from cadavers of horses with known exercise history. PROCEDURES-Tarsi were assigned to 3 groups according to known exercise history as follows: pasture exercise only (PE tarsi), ...
Fontana Karina - - 2010
The effect of mesterolone and intensive treadmill training (6 weeks, 5 days/week, means: 15.82 m/min and 45.8 min/day) in Achilles tendon remodeling was evaluated. Sedentary mice treated with mesterolone (Sed-M) or vehicle (Sed-C, placebo/control) and corresponding exercised (Ex-M and Ex-C) were examined. SDS-polyacrylamide gel electrophoresis was used for determining collagen ...
De Mello Malheiro Olga Cristina - - 2009
Increased activity of matrix metalloproteinases (MMPs) -2 and -9 was found in calcaneal tendon after physical training. However, little attention has been given to the distinct biomechanical and tissue structure of the calcaneal tendon's proximal and distal regions. Herein, we evaluated the effect of two types of physical activities on ...
Henriksen Marius - - 2009
BACKGROUND: Eccentric exercise has been shown to provide good short-term clinical results in the treatment of painful mid-portion chronic Achilles tendinopathies. However, the mechanisms behind the positive effects of eccentric rehabilitation regimes are not known, and research into the biomechanics of the exercise may improve our understanding. METHODS: Sixteen healthy ...
Hawkins David - - 2009
Warm-up exercises are often advocated prior to strenuous exercise, but the warm-up duration and effect on muscle-tendon behavior are not well defined. The gastrocnemius-Achilles tendon complexes of 18 subjects were studied to quantify the dynamic creep response of the Achilles tendon in-vivo and the warm-up dose required for the Achilles ...
Brama Pieter A J - - 2009
We investigated the effects of exercise-induced loading on the collagen network of equine articular cartilage. Collagen fibril architecture at a site (1) subjected to intermittent high-intensity loading was compared with that of an adjacent site (2) sustaining continuous low-level load. From horses exposed to forced exercise (CONDEX group) or not ...
Kjaer M - - 2009
The adaptive response of connective tissue to loading requires increased synthesis and turnover of matrix proteins, with special emphasis on collagen. Collagen formation and degradation in the tendon increases with both acute and chronic loading, and data suggest that a gender difference exists, in that females respond less than males ...
Brama P A J - - 2009
REASONS FOR PERFORMING STUDY: There is ample evidence on topographical heterogeneity of the principal biochemical components of articular cartilage over the surface of the joint and the influence of loading thereon, but no information on depth-related zonal variation in horses. OBJECTIVES: To study depth-related zonal variation in proteoglycan (PG) and ...
Fleenor Bradley S - - 2009
Exercise training (EX) following percutaneous transluminal coronary angiography (PTCA) reduces progression to restenosis and increases event-free survival rates. Our aim was to determine whether EX inhibits lesion development and/or alters the extracellular matrix (ECM) composition of the neointima (NI) in a porcine PTCA model. Miniature Yucatan swine were assigned to ...
Kim Woong - - 2009
OBJECTIVE: To investigate the influence of early conditioning exercise on the development of gross cartilage defects and swelling behavior of cartilage extracellular matrix (ECM) in the midcarpal joint of horses. ANIMALS: 12 Thoroughbreds. PROCEDURES: 6 horses underwent early conditioning exercise from birth to 18 months of age (CONDEX group), and ...
Carmont Michael R - - 2009
INTRODUCTION: Ruptures of the Achilles tendon are common however simultaneous ruptures occur less frequently. Eccentric loading exercise programmes have been used to successfully treat Achilles tendinopathy. CASE REPORT: We report a case of simultaneous bilateral Achilles tendon rupture in a patient predisposed to rupture due to longstanding raised serum lipoprotein ...
Khan K M KM Centre for Hip Health and Mobility and Department of Family Practice, University of British Columbia, Vancouver, Canada. - - 2009
Mechanotransduction is the physiological process where cells sense and respond to mechanical loads. This paper reclaims the term "mechanotherapy" and presents the current scientific knowledge underpinning how load may be used therapeutically to stimulate tissue repair and remodelling in tendon, muscle, cartilage and bone. The purpose of this short article ...
Chung Sangwon - - 2009
Electrospinning has recently received much attention in biomedical applications, and has shown great potential as a novel scaffold fabrication method for tissue engineering. The nano scale diameter of the fibers produced and the structure of the web resemble certain supramolecular features of extracellular matrix which is favorable for cell attachment, ...
Fung David T - - 2009
The mechanical and microstructural bases of tendon fatigue, by which damage accumulates and contributes to degradation, are poorly understood. To investigate the tendon fatigue process, rat flexor digitorum longus tendons were cyclically loaded (1-16 N) until reaching one of three levels of fatigue damage, defined as peak clamp-to-clamp strain magnitudes ...
Kempton Laurence B - - 2009
The early events associated with axonal growth into 10-mm nerve gaps were studied histologically in the rat sciatic nerve model to determine if the outgrowth of blood vessels, Schwann cells, and axons could be enhanced. In the first two experimental groups, collagen nerve guides were filled with either saline or ...
Zhou Jian - - 2009
Physical forces drive the movement of tissues within the early embryo. Classical and modern approaches have been used to infer and, in rare cases, measure mechanical properties and the location and magnitude of forces within embryos. Elongation of the dorsal axis is a crucial event in early vertebrate development, yet ...
Cravero John D - - 2009
The chondrocyte response to insulin-like growth factor 1 (IGF-1) is reduced with aging and in osteoarthritis (OA). IGF-1 signals through the phosphatidylinositol 3-kinase/Akt pathway. TRB3, a tribbles homolog, has been shown to inhibit IGF-1-mediated activation of Akt in HEK 293 cells. This study was undertaken to determine if TRB3 is ...
Shimizu A - - 2009
BACKGROUND: Vaporization around the radiofrequency (RF) electrode after RF application (RFA) limits the RF ablation area. Purpose: To determine whether saturated saline injected into the area of vaporization after initial RFA extends ablation area after further RFA. MATERIAL AND METHODS: RFA was performed in 18 ex vivo porcine livers and ...
Westermeyer Hans D - - 2009
A 4-year-old, castrated male, mixed-breed dog was evaluated because of progressive head swelling, exercise intolerance, and increasing respiratory effort of 1 month's duration. Physical examination and radiographs revealed severe edema of the head and face that was cranial to a circumferential, midcervical constriction caused by scarring related to previous removal ...
Slater Bethany J - - 2009
The tremendous diversity in vertebrate skull formation illustrates the range of forms and functions generated by varying genetic programs. Understanding the molecular basis for this variety may provide us with insights into mechanisms underlying human craniofacial anomalies. In this study, we provide evidence that the anuran Xenopus laevis can be ...
Kubo Keitaro - - 2009
The purpose of this study was to investigate the effects of static and dynamic training on the stiffness and blood volume of the human tendon in vivo. Ten subjects completed 12 wk (4 days/wk) of a unilateral training program for knee extensors. They performed static training on one side [ST; ...
Grigg N L - - 2009
OBJECTIVE: To investigate the acute effects of isolated eccentric and concentric calf muscle exercise on Achilles tendon sagittal thickness. DESIGN: Within-subject, counterbalanced, mixed design. SETTING: Institutional. PARTICIPANTS: 11 healthy, recreationally active male adults. INTERVENTIONS: Participants performed an exercise protocol, which involved isolated eccentric loading of the Achilles tendon of a ...
Jomha Nadr M - - 2009
OBJECTIVE: Osteochondral allografting is an effective method to treat large osteochondral defects but difficulties in tissue preservation have significantly limited the application of this technique. Successful cryopreservation of articular cartilage (AC) could improve the clinical availability of osteochondral tissue and enhance clinical outcomes but cryopreservation of large tissues is hampered ...
Rees J D - - 2009
Eccentric exercises (EE) have proved successful in the management of chronic tendinopathy, particularly of the Achilles and patellar tendons, where they have been shown to be effective in controlled trials. However, numerous questions regarding EE remain. The standard protocols are time-consuming and require very motivated patients. EE are effective in ...
Väänänen Petteri - - 2008
The effect of cyclic loading on the postoperative fixation stability of a biodegradable ankle plate was tested biomechanically during 12 weeks of hydrolytic degradation. Fracture of the lateral malleolus was simulated, and the parameters of cyclic loading were chosen to represent the physiological conditions during the healing period. Additionally, the ...
Lemoine Jennifer K - - 2009
Collagen content and cross-linking are believed to be major determinants of tendon structural integrity and function. Sex and chronic resistance training have been shown to alter tendon function and may also alter the key structural features of tendon. Patellar tendon biopsies were taken from untrained men [n = 8, 1 ...
Hansen Mette - - 2009
The knowledge about the effect of estradiol on tendon connective tissue is limited. Therefore, we studied the influence of estradiol on tendon synthesis, structure, and biomechanical properties in postmenopausal women. Nonusers (control, n = 10) or habitual users of oral estradiol replacement therapy (ERT, n = 10) were studied at ...
Constantinides Georgios - - 2008
A longstanding challenge in accurate mechanical characterization of engineered and biological tissues is maintenance of both stable sample hydration and high instrument signal resolution. Here, we describe the modification of an instrumented indenter to accommodate nanomechanical characterization of biological and synthetic tissues in liquid media, and demonstrate accurate acquisition of ...
Gondret F - - 2009
Pen housing has been proposed in rabbits as an alternative to standard-sized cages. Rabbits reared in pens show greater physical activity. This study investigated whether jump exercise could modify body composition, muscle biochemical and histological characteristics, and some meat quality traits, including the biomechanical properties of tendons. Male weaned rabbits ...
Birch Helen L - - 2008
This study explores the hypothesis that high-intensity exercise induces degenerative changes in the injury-prone equine superficial digital flexor tendon (SDFT), but not in the rarely injured common digital extensor tendon (CDET). The horse represents a large-animal model that is applicable to human tendon and ligament physiology and pathology. Twelve age-matched ...
Etnier S A - - 2008
Late-term fetal bottlenose dolphins (Tursiops truncatus) are bent ventrolaterally en utero, requiring extreme flexibility of the axial skeleton and associated soft tissues. At birth, neonatal dolphins must immediately swim to the surface to breath, yet the dorsoventral oscillations used during locomotion may be compromised by the lateral flexibility evident in ...
Marqueti Rita C - - 2008
Matrix metallopeptidases (MMPs) are responsible for degradation of the extracellular matrix components and tissue remodeling. To achieve a better understanding of AAS effects in rat tendon, MMP-2 activity in the proximal and distal regions of the calcanear tendon (CT) and proximal, intermediate and distal region of superficial (SFT) and deep ...
Lacitignola L - - 2008
To compare cultured bone marrow mesenchymal cells (cBMSC), bone marrow mononucleated cells (BMMNCs), and placebo to repair collagenase-induced tissue damage in an equine model of experimental tendonitis, 6 Standardbred horses with no signs of previous SDF tendon injury have been recruited. Three weeks after collagenase treatment an average of either ...
Schmid Eliane C - - 2008
Current fusionless scoliosis surgical techniques span the intervertebral disc. This alters the spine stiffness, disc pressure equilibrium and possibly may lead to disc degeneration. A new fusionless physeal device was developed that locally modulates vertebral growth by compressing the physeal ring, while maintaining maximum segmental spinal mobility without spanning the ...
Hoffmann G L - - 2008
The clinical and functional results of 46 patients who underwent zone II flexor tendon repair using the Lim/Tsai technique combined with the Kleinert/Duran early active mobilisation regime and place and hold exercises were assessed. The results were compared with 25 patients who were treated by the modified Kessler technique and ...
Urita Yasuhisa - - 2008
Patch closure is necessary to achieve tension-free repair in large congenital diaphragmatic hernia. However, the use of prosthetic material may lead to granulation, allergic reaction, infection, recurrence of hernia, and thoracic deformity. Tissue engineering may become an alternative treatment strategy for diaphragmatic hernia repair, since the regenerated autologous tissue is ...
Adler Ronald S - - 2008
PURPOSE: To test the hypothesis that regional variations in supraspinatus tendon vascularity exist and can be imaged and quantified in asymptomatic individuals by using contrast material-enhanced ultrasonography (US). MATERIALS AND METHODS: After institutional review board approval and informed consent were obtained, 31 volunteers aged 22-65 years (mean age, 41.5 years) ...
Rees J D - - 2008
OBJECTIVE: Degenerative disorders of tendons present an enormous clinical challenge. They are extremely common, prone to recur and existing medical and surgical treatments are generally unsatisfactory. Recently eccentric, but not concentric, exercises have been shown to be highly effective in managing tendinopathy of the Achilles (and other) tendons. The mechanism ...
Dillon Edwin Mark - - 2008
BACKGROUND: Patellar tendinopathy is a common condition affecting the posterior region of the proximal patellar tendon, but the reason for this typical location remains unclear. HYPOTHESIS: The posterior region of the proximal patellar tendon is subjected to greater tendinous forces than is the corresponding anterior region. STUDY DESIGN: Descriptive laboratory ...
Nakamura Kenichi - - 2008
BACKGROUND: Earlier studies have reported positive results from eccentric training in patients with tendon disorders. The reasons for the beneficial clinical effects of eccentric training are not known. Vascularization followed by regression of the vasculature enhances the healing response of injured tendons. Eccentric exercise induces a more beneficial healing response ...
Stecco Carla - - 2008
The aim of this study is to analyse the deep fasciae of limbs in order to evaluate the collagen and elastic fibre arrangement and the types of innervation. Histological and immunohistochemical stains were performed in 72 specimens. The deep fascia of the limbs is a sheath presenting a mean thickness ...
Horiuchi Noriyuki - - 2008
We report the experimental amyloidosis associated with administration of bovine amyloid fibrils in rabbits afflicted by Sore Hock (SH), which is ulcerative pododermatitis. Two groups of SH-afflicted rabbits were subjected to five inflammatory stimulations at intervals of 4 days by intraepithelial injection of a mixture consisting of Freund's complete adjuvant ...
Su Wei-Ren - - 2008
BACKGROUND: Although dynamic stretching is often prescribed before exercise is undertaken, research has rarely been conducted to determine what effects dynamic stretching has on tendon and ligament injury prevention. The hypothesis is that the mechanical properties of tendon and ligament will increase in an ultimate tensile loading test after sinusoid ...
Sunk I-G - - 2008
OBJECTIVE: Dialysis-related amyloidosis (DRA) is a severe complication of maintenance hemodialysis (HD). Given the predominant deposition of beta(2)-microglobulin (beta2m) fibrils on articular cartilage in early DRA, we investigated the significance of beta2m and its relationship to distinct cartilage biomarkers in early DRA diagnosis in HD patients. Furthermore, we assessed the ...
Defontaine Marielle - - 2008
An ultrasound (US) axial transmission technique has been developed to assess in vivo real time tendon biomechanical properties during calibrated exercises. The US propagation velocity changes are indeed related to the tendon visco-elasticity variations. We propose to monitor the propagation velocity changes during a very short period of time corresponding ...
Conrozier T - - 2008
BACKGROUND: Cartilage destruction in osteoarthritis (OA) involves excessive degradation and increased synthesis of cartilage matrix macromolecules including type II collagen and proteoglycans. Cartilage biomarkers exist for the measurement of cartilage matrix turnover and may reveal differences in patients with OA. OBJECTIVE: To determine whether there are detectable differences in and ...
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