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Feldwieser F M - - 2012
Spinal pain can result in unilateral atrophy of spinal muscles. Understanding side-to-side muscle activity during exercises can help clinicians address these deficits. This study determined if variations of bridging exercises specifically activated side-to-side trunk-muscle activity. Using surface electromyography on 20 healthy subjects (16 females), age 25.45 (± 3.57) years, height ...
Burk Andres - - 2012
We examined the effect of heat acclimation (HA) on endurance capacity and blood prolactin (PRL) response to moderate intensity exercise in the heat in young male subjects (n = 21). Three exercise tests (ET) were completed on a treadmill: H1 (walk at 60% VO(2)peak until exhaustion at 42°C), N (walk at 22°C; ...
Sousa Maysa - - 2012
The objective was to determine the effects of carbohydrate (CHO) supplementation on exercise-induced hormone responses and post-training intramyocellular lipid stores (IMCL). Twenty-four elite male athletes (28.0±1.2 years) were randomized to receive CHO (maltodextrin solution) or zero energy placebo solution (control group). The high-intensity running protocol consisted of 10×800 m at 100% ...
González-Agüero Alejandro - - 2012
Aim  To determine whether the bone mass of young people with Down syndrome may increase, following a 21-week conditioning training programme including plyometric jumps. Method  Twenty-eight participants with Down syndrome (13 females, 15 males) aged 10 to 19 years were divided into exercise (DS-E; n=14; eight females, six males mean age ...
Kumae Takashi - - 2012
To clarify the effects of forced or voluntary exercise on autonomic modulation of the cardiovascular system, we monitored changes in autonomic nervous activity in a mature rat by spectral analysis of the heart rate (HR) during a 10-week training period. Male Wistar rats implanted with a radio-telemetry system were divided ...
Kounalakis Stylianos N - - 2012
The potentiated exercise-sweating rate observed during acute hypoxia is diminished after a sleep-high train-low (SH-TL) regimen. We tested the hypothesis that this attenuation of the sweating response after SH-TL is compensated for by an increase in heat loss via vasodilatation. Nine male subjects participated in a 28-day SH-TL regimen. Before ...
Mortensen Stefan P - - 2012
During exercise, contracting muscles can override sympathetic vasoconstrictor activity (functional sympatholysis). ATP and adenosine have been proposed to play a role in skeletal muscle blood flow regulation. However, little is known about the role of muscle training status on functional sympatholysis, ATP and adenosine induced vasodilation. Eight male subjects (22±2 ...
Biensø Rasmus S - - 2012
To elucidate the molecular mechanisms behind physical inactivity-induced insulin resistance in skeletal muscle, 12 young, healthy male subjects completed 7 days of bed rest with vastus lateralis muscle biopsies obtained before and after. In six of the subjects, muscle biopsies were taken from both legs before and after a 3-h ...
Villarroya Francesc - - 2012
Exercise exerts beneficial effects on systemic metabolism. A recent Nature paper (Boström et al., 2012) identifies irisin as an exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin promotes brown adipocyte recruitment in white fat and improves systemic metabolism by increasing energy expenditure.
Oosthuyse Tanja - - 2012
Early animal, menstrual phase and gender comparative studies inconsistently support an oestrogen-induced increase in fat oxidation during exercise. Recent advances from studies of cellular signalling and gene expression provide evidence for inter-tissue and intramuscular mechanisms that demonstrate oestrogen's promotion of skeletal muscle fat oxidative capacity. Oestrogen or oestrogen-analogues act mainly ...
Bianchi Renata Cristiane Gennari - - 2012
To study if the pre-radiotherapy physical activity has radio-protective elements, by measuring the radio-induced activation of pro-inflammatory cytokines as interleukin-6 (il-6), transforming growth factor -β (tgf -β), tumor necrosis factor -α (tnf-α) and protein beta kinase β (ikkβ), through western blotting analysis. A randomized study with 28 Wistar hannover rats, ...
Shavandi Nader - - 2012
Post exercise proteinuria and increased urinary Gamma-Glutamyl transferase (GGT) levels can be indicative of exercise-induced renal damage. The aim of this investigation is to study the effect of one session of intensive training on renal damage markers and compare their values to those 6 hours after training. In this cross-sectional ...
Pelliccia Antonio - - 2012
Remodeling of the aortic root may be expected to occur in athletes as a consequence of hemodynamic overload associated with exercise training; however, there are few data reporting its presence or extent. This review reports the current knowledge regarding the prevalence, upper limits, and clinical significance of aortic remodeling induced ...
Izawa Kazuhiro P - - 2012
Exercise capacity of fewer than 5 metabolic equivalents (METs) has been associated with high risk of death and poor physical functioning in male patients with heart failure (HF). Therefore, we aimed to determine upper and lower extremity muscle strength levels required to attain an exercise capacity of 5 or more ...
Park Sookyoung - - 2012
Exercise training can improve strength and lead to adaptations in the skeletal muscle and nervous systems. Skeletal muscles can develop into two types: fast and slow, depending on the expression pattern of myosin heavy chain (MHC) isoforms. Previous studies reported that exercise altered the distribution of muscle fiber types. It ...
Ogedengbe John Onimisi - - 2012
A study was conducted to determine the effect of exercise on Electrocardiogram (ECG) variables in students of University of Abuja, and gender variation of these variables was compared. Forty medical students were considered (22 males and 18 females), ages 18-30 years. The volunteers were subjected to exercise stress test by ...
Chłopicki Stefan - - 2012
Background: Methylnicotinamide (MNA) displays vasoprotective activity, however, the regulation of the activity of nicotinamide-N-methyltransferase (NNMT), is largely unknown. We analyze a possible involvement of IL-6 in the activation of NNMT-MNA pathway during an endurance exercise. Methods: FVB, C57Bl/6J IL6(+/+) and C57Bl/6J IL-6(-/-) mice were subjected to the single bout of ...
Wise Frances M - - 2012
Chronic heart failure (CHF) is a leading cause of morbidity in the industrialized world; both men and women are affected in significant numbers. However, women are underrepresented in heart failure literature, and there is limited evidence of their cardiac rehabilitation outcomes. The purpose of this study was to examine the ...
Ludlow Andrew T - - 2012
We evaluated the impact of long-term exercise on telomere dynamics in wild-derived short telomere mice (CAST/Ei) over 1 year. We observed significant telomere shortening in liver and cardiac tissues in sedentary 1-year-old mice compared with young (8 weeks) baseline mice that were attenuated in exercised 1-year-old animals. In contrast, skeletal ...
Tendera Michal - - 2012
BACKGROUND: Anti-ischaemic effect of A1 adenosine receptor agonists was shown in animal and preclinical studies. The present proof-of-concept study aimed at evaluation of the efficacy and safety of a new adenosine A1 receptor agonist capadenoson in patients with stable angina. METHODS: This was a randomized, double-blind, placebo-controlled, single dose-escalating, multicenter ...
Xiong Ruohong - - 2012
The female reproductive system is highly sensitive to physiological stress. However, the mechanism(s) involved in dysfunction of the ovaries induced by high intensity exercise training remain unknown. In the present study, we established a rat model of high intensity exercise training, and investigated the morphological and functional changes in ovaries. ...
Carroll Chad C - - 2012
Chronic consumption of acetaminophen (APAP) during exercise training leads to a reduction in tendon stiffness and modulus when compared to a placebo. We explored whether this effect could be due to a reduction in tendon collagen content or cross-linking. Ten-week-old male Wistar rats (n=50) were divided into placebo or APAP ...
Petkus Vytautas - - 2012
BACKGROUND AND OBJECTIVE. A novel noninvasive monitor is presented by demonstrating its capabilities to perform the real-time estimation of dynamics in cerebrovascular autoregulation in athletes during their training. The aim was to explore the characteristics of human cerebrovascular autoregulation by performing the monitoring of cerebrovascular autoregulation responses to resistance exercises ...
Laker Rhianna C - - 2012
We have previously shown that 4 wk of exercise training early in life normalizes the otherwise greatly reduced pancreatic β-cell mass in adult male rats born small. The aim of the current study was to determine whether a similar normalization in adulthood of reduced skeletal muscle mitochondrial biogenesis markers and ...
Bada A A - - 2012
In dogs, manipulation of heart rate has no effect on the exercise-induced increase in cardiac output. Whether these findings apply to humans remain uncertain, because of the large differences in cardiovascular anatomy and regulation. To investigate the role of heart rate and peripheral vasodilatation in the regulation of cardiac output ...
Borgenvik Marcus - - 2012
This investigation was designed to evaluate changes in plasma and muscle levels of free amino acids during an ultra-endurance exercise and following recovery. Nine male ultra-endurance trained athletes participated in a 24-h standardized endurance trial with controlled energy intake. The participants performed 12 sessions of running, kayaking and cycling (4 × each ...
Jamart Cécile - - 2012
In this study, the coordinated activation of ubiquitin-proteasome pathway (UPP), autophagy-lysosomal pathway (ALP), and mitochondrial remodeling including mitophagy was assessed by measuring protein markers during ultra-endurance running exercise in human skeletal muscle. Eleven male, experienced ultra-endurance athletes ran for 24 h on a treadmill. Muscle biopsy samples were taken from ...
Kyriazis Stephanie M - - 2012
PURPOSE: Prevention of the female athlete triad is essential to protect female athletes' health. The aim of this study was to investigate the knowledge, attitudes and behaviours of regularly exercising adult females towards eating patterns, menstrual cycles and bone health. METHODS: A total of 191 female exercisers, aged 18-40 y, ...
Banzet Sébastien - - 2012
The iron regulatory peptide hormone hepcidin has been proposed to participate in training-induced iron deficiency. Plasma and urinary hepcidin increase in response to one bout of prolonged exercise, a condition also known to increase plasma interleukin-6 (Il-6). Because Il-6 activates hepcidin transcription and expression during inflammation, our aim was to ...
Sawyer Brandon J - - 2012
PURPOSE: This study was designed to determine whether VO2 reaches a maximum, equivalent to that attained in an incremental exercise test to exhaustion, during "submaximal" fatigue-inducing constant-power exercise bouts above Critical Power (CP). METHODS: Nine males (age: 24.6 ± 3.6 yr.; ht: 182.8 ± 6.9 cm; wt: 77.8 ± 12.1 ...
Foncea Hermann Zbinden - - 2012
PURPOSE: Toll-like receptors 2 and 4 (TLR2, TLR4) are found in the membrane of skeletal muscle cells. A variety of molecular components can activate TLR2 and TLR4, amongst others long chain fatty acids. The subsequent downstream signalling triggers the MAPK and NF-κB pathways. Therefore, the purpose of this study was ...
Hautala Arto - - 2012
Abstract We hypothesised that habitual physical activity (PA) together with progressive endurance training contributes to the differences in training response (Δ[Vdot]O(2max)) in healthy and physically active male participants. Twenty volunteers (age 30±3 years and [Vdot]O(2max) 54±7 ml·kg(-1)·min(-1)) participated in an eight-week training program which included four to six heart rate-guided ...
Di Luigi Luigi - - 2012
Phosphodiesterase type 5 inhibitors may influence human physiology, health, and performance by also modulating endocrine pathways. We evaluated the effects of a 2-day tadalafil administration on adenohypophyseal and adrenal hormone adaptation to exercise in humans. Fourteen healthy males were included in a double-blind crossover trial. Each volunteer randomly received two ...
Ekstrom Richard A - - 2012
Ekstrom, RA, MS, Osborn, RW, Goehner, HM, Moen, AC, Ommen, BM, Mefferd, MJ, Bergman, TR, Molencamp, TB, and Kelsey, SA. Electromyographic normalization procedures for determining exercise intensity of closed chain exercises for strengthening the quadriceps femoris muscles. J Strength Cond Res 26(3): 766-771, 2012-The purpose of this study was to ...
Caruso John F - - 2012
Caruso, JF, Lutz, BM, Davidson, ME, Wilson, K, Crane, CS, Craig, CE, Nissen, TE, Mason, ML, Coday, MA, Sheaff, RJ, and Potter, WT. Salivary hormonal values from high-speed resistive exercise workouts. J Strength Cond Res 26(3): 625-632, 2012-Our study purpose examined salivary hormonal responses to high-speed resistive exercise. Healthy subjects ...
Zhou Zhichao - - 2012
A significant endothelium-dependent vasodilation persists after inhibition of nitric oxide synthase (NOS) and cyclo-oxygenase (COX) in the coronary vasculature, which has been linked to the activation of cytochrome P450 (CYP) epoxygenases expressed in endothelial cells, and subsequent generation of vasodilator epoxyeicosatrienoic acids (EETs). Here, we investigated the contribution of CYP ...
Li Gebin - - 2012
Continuous high intensity training may induce alterations to enzyme activities related to glucose and lipid metabolism in horses. In our study, five Thoroughbred race horses (3 male and 2 female, avg age = 5 yrs old) were compared against five riding horses (1 male, 1 female, 3 gelding, avg age = 13 yrs old) in terms ...
Oliver Gretchen D - - 2012
The RAZOR curl has been introduced as a hamstring exercise. However, modifications to the exercise have been developed which are proposed to utilize some of the muscles of the lumbo-pelvic-hip complex. Thus, it was the purpose of this study to quantitatively examine the modified RAZOR curl using surface electromyography (sEMG), ...
Li Lu L Department of Pharmacology, Institute of Chinese Integrative Medicine, Hebei Medical University, Shijiazhuang, - - 2012
To investigate the effects of exhaustive swimming exercise on P2X1 receptor- and α1-adrenoceptor-mediated vasoconstriction of different types of arteries in rats. Male Wistar rats were divided into 2 groups: the sedentary control group (SCG) and the exhaustive swimming exercise group (ESEG). The rats in the ESEG were subjected to a ...
Roman-Campos Danilo - - 2012
Hypertension leads to electrophysiological changes in the heart. Chronic exercise induced by a treadmill-running programme (TRP) is considered a potential non-pharmacological treatment for hypertension and may have implications in heart remodelling. However, it is not known whether the TRP is able to improve the electrophysiological properties of the heart in ...
Yan Wen-Wen - - 2012
There is no research, either at home or abroad, focusing on assessing the cardiopulmonary functional reserve and exercise tolerance in patients with pulmonary embolism (PE), but the benefits of early exercise are well recognized. The goals of this study were to assess cardiopulmonary functional reserve in treated PE patients using ...
Radom-Aizik Shlomit S Pediatric Exercise Research Center, Department of Pediatrics, University of California Irvine, - - 2012
MicroRNAs are increasingly seen as targets of drug discovery because they influence gene function acting both to silence and subtly modulate protein translation. Little is known about effects of dynamic physiological states on microRNA regulation in humans. We hypothesized that microRNA expression in peripheral blood mononuclear cells (PBMCs) would be ...
Marqueti R C - - 2012
The indiscriminate use of anabolic-androgenic steroids has been shown to induce left ventricular dysfunctions. The main objective of the present study was to investigate the effects of nandrolone decanoate on matrix metalloprotease (MMP-2) activity and protein level in the left ventricle (LV) of rats after 7 weeks of mechanical load ...
Molmen Harald Edvard - - 2012
Abstract Objectives: To study the effect of aerobic interval training (AIT) on myocardial function in sedentary seniors compared to Master athletes (MA) and young controls. Design: 16 seniors (72 ±1 years, 10 men) performed AIT (4x4minutes) at ∼90% of maximal heart rate 3 times/ week for 12 weeks. Results were ...
Kanarek Robin B - - 2012
Exercise is endorsed for its physiological and psychological benefits, and has been proposed to have positive effects on impression formation. To test this proposal, 62 female and 44 male college students read one of three brief descriptions of either a fictitious male or female "target" student. The descriptions varied only ...
Rowe Glenn C GC Cardiovascular Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of - - 2012
Exercise confers numerous health benefits, many of which are thought to stem from exercise-induced mitochondrial biogenesis (EIMB) in skeletal muscle. The transcriptional coactivator PGC-1α, a potent regulator of metabolism in numerous tissues, is widely believed to be required for EIMB. We show here that this is not the case. Mice ...
Sugama Kaoru - - 2012
The T-cell subset Th17 is induced partly by interleukin (IL)-6 and activated by IL-23, and produces a proinflammatory cytokine IL-17. Since IL-6 increases dramatically following long-lasting endurance exercise, this response may also stimulate the induction of IL-17 and IL-23 after exercise. The aim of this study was to clarify the ...
Vegge Geir - - 2012
The effect on performance of protein ingestion during or after exercise is not clear. This has largely been attributed to the utilization of different scientific protocols and the neglection of accounting for factors such as differences in physical and chemical properties of protein supplements and differences in athletic performance level. ...
Howatson Glyn G School of Life Sciences, Northumbria University, Newcastle upon Tyne, UK ; School of Environmental Sciences and Development, Northwest University, Potchefstroom, South - - 2012
It is well documented that exercise-induced muscle damage (EIMD) decreases muscle function and causes soreness and discomfort. Branched-chain amino acid (BCAA) supplementation has been shown to increase protein synthesis and decrease muscle protein breakdown, however, the effects of BCAAs on recovery from damaging resistance training are unclear. Therefore, the aim ...
Larson-Meyer D Enette - - 2012
Nine female runners and ten walkers completed a 60 min moderate-intensity (70% VO(2)max) run or walk, or 60 min rest in counterbalanced order. Plasma concentrations of the orexogenic peptide ghrelin, anorexogenic peptides peptide YY (PYY), glucagon-like peptide-1 (GLP-1), and appetite ratings were measured at 30 min interval for 120 min, followed by a free-choice ...
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