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Results 201 - 250 of 706
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Dokladny Karol K Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, - - 2013
The eukaryotic cell depends on multitiered homeostatic systems ensuring maintenance of proteostasis, organellar integrity, function and turnover, and overall cellular viability. At the two opposite ends of the homeostatic system spectrum are heat shock response and autophagy. Here, we tested whether there are interactions between these homeostatic systems, one universally ...
Doheny Emer P - - 2013
Aging-related decline in functional mobility is associated with loss of independence. This decline may be mitigated through programs of physical activity. Despite reports of aging-related mobility impairment in middle-aged adults, this age group has been largely overlooked in terms of exercise programs that target functional mobility and the preservation of ...
Taylor Bryan J - - 2013
To determine whether expiratory muscle fatigue (EMF) is involved in regulating operating lung volumes during exercise, nine recreationally-active subjects cycled at 90% of peak work rate to the limit of tolerance with prior induction of EMF (EMF-ex) and for a time equal to that achieved in EMF-ex without prior induction ...
Idorn Lars - - 2013
Background: Patients with a functionally univentricular heart, palliated a.m. Fontan, consequently have non-pulsatile pulmonary blood flow and are known to have a reduced pulmonary diffusing capacity. However, the cause of this reduction remains unclear. We aimed to assess the possible determinants in the aetiology of a reduced diffusing capacity and ...
Selkow Noelle M NM School of Kinesiology and Recreation, Illinois State University, Normal, IL 61761, USA. - - 2013
The purpose of this study was to assess microvascular perfusion immediately after eccentric exercise using contrast-enhanced sonography. An intravenous catheter was placed in the antecubital vein of the arm contralateral to the leg being tested for the delivery of microbubbles to 18 healthy volunteers (mean age ± SD, 22.2 ± ...
Galy Olivier O ACTES Laboratory, Formation and Research of Science and Techniques of Physical and Sport Activities Unit Antilles-Guyane, Pointe à Pitre, - - 2013
Postexercise alveolar-capillary membrane-diffusing capacity (DLco) often decreases in highly trained endurance athletes and seems linked to their training status. To test the hypothesis that training status influences postexercise DLco, 13 male and 2 female triathletes (20.2 ± 4.4 y old, 175.2 ± 6.7 cm tall; weight in a range of ...
Smith Michael M - - 2013
This study examined the relationship between hematocrit, blood viscosity, plasma viscosity, erythrocyte deformability, and fibrinogen concentration during maximal oxygen uptake in aerobically trained (AT) and resistance trained (RT) athletes. Maximal oxygen uptake was assessed using a Bruce graded exercise treadmill test to exhaustion, and blood samples were collected at rest ...
Lahaije Anke J M C - - 2013
BACKGROUND: Physical activity and health status deteriorate early in the course of chronic obstructive pulmonary disease (COPD). This can only partially be explained by the degree of airflow limitation. Changes in (resting and dynamic) lung volumes are known to be associated with functional impairments and thus might influence physical activity ...
Rowland Thomas - - 2013
Understanding cardiac responses to exercise in healthy subjects is important in the evaluation of youth with heart disease. This review article incorporates previously published original research from the authors' laboratory to examine changes in stroke volume during progressive exercise which are consistent with a model in which circulatory responses are ...
Furrow Eva - - 2013
Objective-To identify characteristics of exercise-induced collapse in Labrador Retrievers and compare characteristics for dogs with various dynamin 1 gene (DNM1) mutation statuses. Design-Retrospective cross-sectional study. Animals-109 Labrador Retrievers with a history of recurrent exercise-induced collapse, clinically normal behavior and gait between episodes, and no reason for collapse identified via medical ...
Reddy Sushma S Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA. - - 2013
Pulmonary insufficiency (PI) is a common long-term sequel after repair of tetralogy of Fallot, causing progressive right ventricular (RV) dilation and failure. We describe the physiologic and molecular characteristics of the first murine model of RV volume overload. PI was created by entrapping the pulmonary valve leaflets with sutures. Imaging, ...
Brolo Alexandre G - - 2013
Periodic plasmonic nanostructures are being widely studied, optimized and developed to produce a new generation of low-cost and efficient chemical sensors and biosensors. The wide variety of nanostructures, interrogation approach, and setups makes a direct comparison of the reported performance from different sensing platforms a challenging exercise. In this feature ...
Brun J-F - - 2013
Classic studies on exercise hemorheology evidenced that blood fluidity is impaired during exercise (short term exercise-induced hyperviscosity) and is improved as a result of regular exercise practice (hemorheologic fitness). Extensive description of these events led to the concepts of "the triphasic effects of exercise", "the paradox of hematocrit", and "the ...
Dolmage Thomas E - - 2013
Measuring the severity of dynamic hyperinflation is a useful clinical approach to assess the effect of therapeutic interventions and explain their impact on exercise tolerance. Dynamic hyperinflation is typically quantified by the change in end expiratory lung volume from rest to the end of exercise. The result may be inconsistent ...
Currie Katharine D - - 2013
Purpose: Isocaloric interval exercise training programs have been shown to elicit improvements in numerous physiological indices in patients with coronary artery disease (CAD). Low-volume high-intensity interval exercise training (HIT) is effective in healthy populations; however its effectiveness in cardiac rehabilitation has not been established. This study compared the effects of ...
Pongdee Thanai - - 2013
To review the literature regarding the pathophysiology of exercise-induced bronchoconstriction (EIB). The databases of PubMed, Ovid MEDLINE, and Scopus were searched for articles using the subject headings and/or keywords asthma, exercise-induced/etiology, exercise, mechanism, pathogenesis, and bronchoconstriction. Articles were selected based on their relevance to the focus of this review, with ...
Wasenius Niko N Department of General Practice and Primary Health Care, Institute of Clinical Medicine, Faculty of Medicine, University of Helsinki, Helsinki, Finland. - - 2013
To determine the intensity and volume of therapeutic exercises during a standard 13-day inpatient neck rehabilitation course in relation to overall physical activity in rehabilitation and everyday life. Cross-sectional study. Subjects (n = 19; 16 women and 3 men; mean age 48.6 years, standard deviation (SD) 6.6) with chronic non-specific neck pain ...
Vromen T - - 2013
To assess methods for determination of exercise intensity, and to investigate practice variation with respect to the contents, volume and intensity of exercise training programs in Dutch cardiac rehabilitation (CR) centres. A paper questionnaire was sent to all Dutch CR centres, consisting of 85 questions for patients with an acute ...
Foster Philip P - - 2013
To reduce bubble formation and growth during hypobaric exposures, a denitrogenation or nitrogen "washout" procedure is performed. This procedure consists of prebreathing oxygen fractions as close to one as possible (oxygen prebreathe) prior to depressurization before ascending to the working altitude or low spacesuit pressures. During the NASA prebreathe reduction ...
Fatima Syeda Sadia - - 2013
To assess and compare changes in pulmonary functions before and after exercise in young healthy adults. The case-control study was carried out from January to March 2010 on 292 medical students aged 18-24 years at Bahria University Medical and Dental College, Karachi. Baseline values for forced expiratory volume (FEV1) and ...
Welvaart Willem N - - 2013
OBJECTIVES: Paralysis of the diaphragm is an uncommon condition, which may result in dyspnoea on excertion and in orthopnea. In patients who have symptoms, the paralysed diaphragm is often plicated to prevent its paradoxical movement on inspiration. This procedure brings relief to many patients, but the mechanism for this improvement ...
Tang Kechun K Department of Medicine, University of California, San Diego, La Jolla, California 92093-0623, - - 2013
Pulmonary TNFα has been linked to reduced exercise capacity in a subset of patients with moderate to severe chronic obstructive pulmonary disease (COPD). We hypothesized that prolonged, high expression of pulmonary TNFα impairs cardiac and skeletal muscle function, and both contribute to exercise limitation. Using a surfactant protein C promoter-TNFα ...
Walter Ashley A - - 2013
ABSTRACT: The purpose of this study was to examine the effects of two different types of protein supplementation on thigh muscle cross-sectional area, blood markers, muscular strength, endurance, and body composition after eight weeks of low- or moderate-volume resistance training in healthy, recreationally trained, college-aged men. One hundred and six ...
Cadore Eduardo Lusa - - 2013
ABSTRACT: The purpose of this study was to investigate the effect of different volumes of plyometric exercise (i.e., 100, 200, or 300 hurdle jumps) on acute strength and jump performance as well as on the acute hormonal and lactate responses in rugby players. Eleven young male elite rugby players (age, ...
Fahs C A - - 2013
The relationship between effective arterial elastance (E(A)) and left ventricular end-systolic elastance (E(LV)) is a determinant of cardiac performance, known as arterial-ventricular coupling (AVC). The purpose of this study was to examine the acute effects of high-intensity interval (HI) and low-intensity steady state (SS) exercise on AVC. Twenty-three (13 men, ...
Bechara R G - - 2013
Exercise and environmental enrichment are behavioural interventions that have been shown to improve learning and increase neurogenesis in rodents, possibly via neurotrophin-mediated mechanisms. However, many enrichment protocols incorporate exercise, which can itself be viewed as a source of cognitive stimulation in animals housed in standard laboratory conditions. In this experiment ...
Bovenschen H Jorn HJ Radboud University Nijmegen Medical Centre, The - - 2013
To assess the effect of graduated compression stockings (GCS) on lower leg volume and leg complaints in runners during and after exercise. Cross-sectional study. Radboud University Nijmegen Medical Centre and an outdoor running track in Nijmegen, The Netherlands. Thirteen Dutch trained recreational runners. Participants used a GCS on 1 leg ...
Guenette Jordan A - - 2013
The purpose of this exploratory physiological study was to evaluate the effects of inhaled fluticasone/salmeterol combination (FSC) on sensory and physiological responses to exercise in subjects with mild-to-moderate COPD. In a randomized, double-blind, placebo-controlled, crossover study, subjects underwent 6-week treatments with FSC or placebo (PLA). Detailed pulmonary function and constant-work ...
Pingel Jessica - - 2013
Real-time harmonic contrast-enhanced ultrasound (CEU) is used in several diseases to visualize the microvascularization in various tissues, due to its high sensitivity. The aim of the present study was to investigate whether CEU could be used to detect an increase in the microvascular volume (MV) in healthy tendon tissue in ...
Fontinele Renata Gabriel - - 2013
OBJECTIVE: To check if ovariectomy produces alterations in the articular cartilage structure of the tibial proximal epiphysis and if aerobic physical exercise has any influence on these alterations. METHODS: Six-month-old female Wistar rats were distributed in three groups: Control group (CG), without ovariectomy and physical activity; Oophorectomy and sedentary group ...
Spence Angela L - - 2013
Cardiac adaptation in response to exercise has historically been described using echocardiography. Cardiac magnetic resonance (CMR) however, has evolved as a preferred imaging methodology for cardiac morphological assessment. While direct imaging modality comparisons in athletes suggest that large absolute differences in cardiac dimensions exist, it is currently unknown whether changes ...
Ezeugwu Victor Emeka - - 2013
BACKGROUND AND PURPOSE: Reduced endurance and excessive fatigue in stroke survivors (SS) during exercise may be linked to impairment of lung function and breathing mechanics, but little is known about lung function of SS. The purpose of this study is to determine lung function (forced expiratory volume in 1 second [FEV(1) ...
von Knobelsdorff-Brenkenhoff Florian - - 2013
PURPOSE: To establish a suitable setup for combining isometric handgrip exercise with cardiovascular magnetic resonance (CMR) imaging and to assess cardiovascular effects. MATERIALS AND METHODS: Fifty-three healthy volunteers (31 males, mean age 45 ± 17 years) underwent handgrip exercise in a 3T scanner using a prototype handgrip system and a ...
Romagnoli I - - 2013
We hypothesized that arm training might affect unsupported arm exercise-related perception by decreasing motor output to arm/torso muscles in patients with chronic obstructive pulmonary disease (COPD). Eleven patients were studied at 80% of peak incremental arm exercise, before and after unsupported arm training. Training increased endurance time, decreased respiratory effort ...
Rodrigues Miguel K - - 2013
It is currently unknown whether potential haemodynamic improvements induced by non-invasive ventilation (NIV) would positively impact upon cerebral oxygenation (COx) in patients with moderate-to-severe chronic obstructive pulmonary disease (COPD). To investigate the effects of NIV on exercise COx in COPD patients presenting with exercise-related O2 desaturation. On a double-blind trial, ...
Bloomer Richard J - - 2013
ABSTRACT: When exercise is of long duration or of moderate to high intensity, a decrease in plasma volume can be observed. This has been noted for both aerobic and resistance exercise but few data are available with regards to high intensity sprint exercise. We measured plasma volume before and following ...
Romagnoli Marco - - 2013
Nowadays cardiac and metabolic diseases are a matter of concern. Exercise is a valid treatment and method of prevention for not only adults, but also young subjects. Physical activity causes transient blood rheology impairment in adults. However little is known about the effects of exercise on blood flow characteristics in ...
Cadore E L EL Exercise Research Laboratory, Physical Education School, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, - - 2013
The purpose of the present study was to review the scientific literature that investigated concurrent training adaptations in elderly populations, with the aim of identifying the optimal combination of both training program variables (i.e., strength and endurance) to avoid or minimize the interference effect in the elderly. Scielo, Science Citation ...
Lan Chou-Chin - - 2013
Background:Pulmonary rehabilitation (PR) is beneficial for patients with chronic obstructive pulmonary disease (COPD) with improvement in exercise capacity, healthy-related quality of life (HRQL). Despite these overall benefits, the responses to PR vary significantly among different individuals. It is not clear if PR is beneficial for patients with COPD with normal ...
Huang Chun-Xia - - 2013
Previous studies have shown that running exercise could increase regional cerebral blood flow. There have been previous studies investigating the effects of running exercise on capillary density in brain and showing that running exercise could induce brain angiogenesis. However, there have been no studies investigating the effects of running exercise ...
Zhang Pengyue - - 2013
Early exercise is an effective strategy for stroke treatment, but the underlying mechanism remains poorly understood. Apoptosis plays a critical role after stroke. However, it is unclear whether early exercise inhibits apoptosis after stroke. The present study investigated the effect of early exercise on apoptosis induced by ischemia. Adult SD ...
Tantucci Claudio - - 2013
When expiratory flow is maximal during tidal breathing and cannot be increased unless operative lung volumes move towards total lung capacity, tidal expiratory flow limitation (EFL) is said to occur. EFL represents a severe mechanical constraint caused by different mechanisms and observed in different conditions, but it is more relevant ...
Guerrero Cesar - - 2013
The Kinect sensor has opened the path for developing numerous applications in several different areas. Medical and health applications are benefiting from the Kinect as it allows non-invasive body motion capture that can be used in motor rehabilitation and phobia treatment. A major advantage of the Kinect is that allows ...
Guenette Jordan A - - 2013
Cardiopulmonary exercise testing (CPET) is an established method for evaluating dyspnea and ventilatory abnormalities. Ventilatory reserve is typically assessed as the ratio of peak exercise ventilation to maximal voluntary ventilation. Unfortunately, this crude assessment provides limited data on the factors that limit the normal ventilatory response to exercise. Additional measurements ...
Altamirano-Diaz Luis A - - 2013
Despite improved ventricular function after heart transplantation, the aerobic capacity, as measured by peak oxygen consumption (VO(2peak)) of pediatric heart transplant recipients (HTRs), remains 30% to 50% lower than age-matched healthy individuals. Research in adult HTRs suggests that diastolic dysfunction is a major determinant of exercise intolerance; however, it is ...
Ramos Roberta P - - 2013
The advent of microprocessed "metabolic carts" and rapidly incremental protocols greatly expanded the clinical applications of cardiopulmonary exercise testing (CPET). The response normalcy to CPET is more commonly appreciated at discrete time points, for example, at the estimated lactate threshold and at peak exercise. Analysis of the response profiles of ...
Naclerio Fernando - - 2013
The effects of a 4-week lower body injury prevention program on knee muscle torque-angle relationship were examined in soccer players. Twenty men were randomly allocated to either a control (n = 10) or training group (n = 10). The training group underwent three training sessions per week, comprising 3 sets of 8 repetitions of ...
Walzer Chris - - 2013
The European Alps harbour a unique and species-rich biodiversity, which is increasingly impacted by habitat fragmentation through land-use changes, urbanization and expanding transport infrastructure. In this study, we identified the 50 most important questions relating to the maintenance and restoration of an ecological continuum - the connectedness of ecological processes ...
Fernández-Luna Alvaro - - 2013
Swimming in indoor pools treated with combined chemical treatments (e.g. ozone) may reduce direct exposure to disinfection byproducts and thus have less negative effects on respiratory function compared to chlorinated pools. The aim of this study is to analyze the effects of a short-term training intervention on respiratory function and ...
Gibala Martin J - - 2013
High-intensity interval training (HIIT) refers to exercise that is characterized by relatively short bursts of vigorous activity, interspersed by periods of rest or low-intensity exercise for recovery. In untrained and recreationally active individuals, short-term HIIT is a potent stimulus to induce physiological remodeling similar to traditional endurance training despite a ...
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