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Results 301 - 350 of 450
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Mannix E T - - 1990
Phosphate has been proposed as an ergogenic aid since it may enhance O2 delivery and cardiac work efficiency by increasing plasma phosphate (P Pi), red blood cell phosphate (RBC Pi), 2,3-diphosphoglycerate (DPG), RBC adenosine triphosphate (ATP), and P50. In 10 normal, fasting males we measured cardiac output (Q) by CO2 ...
Bartels P C - - 1990
A longitudinal investigation of changes in red blood cell (RBC) size distribution and zinc protoporphyrin/haemoglobin (ZPP/Hb) ratio was performed. In the course of the first few weeks after birth RBC size distribution histograms show a loss of macrocytic RBCs demonstrated by a rapid decrease of the fraction of macrocytes, whereas ...
Mercy J A - - 1990
A review of police records for the nine-year period from 1974 to 1982 identified 20 men who died following restraint by an upper-body control hold while in the custody of a large, urban police department. Using evidence from autopsy findings and police reports of events immediately preceding death, we concluded ...
Walter S V - - 1990
A negative chronotropic effect of bovine stroma-free hemoglobin was identified in spontaneously contracting myocardiocytes derived from neonatal rats. This model allowed for the evaluation of direct effects of hemoglobin solutions without the influence of hemodynamic reflexes. Significant slowing of myocardiocyte beating rates were observed from 0.8 to 11.6 g.dl-1 stroma-free ...
Ercan M T - - 1990
A new method of labelling human RBCs with 99mTc by the use of Sn-alpha-D-glucose 1-phosphate (GP) is presented. It was tested for spleen imaging in 16 normal volunteers. The labelling was carried out during the heating (30 min at 49.5 degrees C) to damage the cells and cooling (10 min ...
Hendler E D - - 1990
Effects of androgens on red blood cell (RBC) oxygen transport, RBC metabolism and work capacity in chronic hemodialysis patients were evaluated in a prospective controlled study. Compared to control subjects, patients given nandrolone decanoate had a sustained fall in RBC ATP and a transient rise in RBC DPG but P50 ...
Hampl H - - 1990
Renal anemia is the result of reduced erythropoietin (EPO) biosynthesis in the diseased kidney and also in part the result of a reduced life span of red blood cells (RBCs). An increase in density and a decrease in enzyme equipment (aspartate aminotransferase; GOT) of RBCs reflect cell age. In the ...
Nayak N C - - 1989
Synovial fluid samples of goat kids inoculated (ip) with 5 ml of 48 hr log phase culture of Mycoplasma mycoides sub sp. mycoides (large colony type) containing 10(7) cfu/ml were analysed for physical, cytological and biochemical properties. The synovial effusions were exudative in nature with increased volume. Gross appearances were ...
Arafat A M - - 1989
The erythrocytic glutathione reductase activity was studied among 40 normal and G 6 PD-deficient males without or with intestinal parasitic infection. The results showed that the incidence of vitamin B2 deficiency was significantly higher (chi 2 P less than 0.05) among G 6 PD deficient subjects compared to corresponding incidence ...
Mendis S - - 1989
Atomic absorption spectrometry was used in a quantitative study of zinc, magnesium, and manganese on 71 postmortal human aortas. Samples were obtained from accident victims 35-65 years of age. Fibrous plaques had higher levels of all three elements when compared to normal aortic tissue. The difference was significant for zinc ...
Smith J E - - 1989
Five horses were exercised at 10m/sec at a 3 degree incline for 2 mins. Packed cell volume, erythrocyte count, haemoglobin concentration, mean corpuscular volume, plasma protein, total white cell count and lymphocytes increased significantly in blood samples taken after exercise, compared with those taken before exercise; but mean corpuscular haemoglobin ...
Chen H I - - 1989
Twenty-five men and 26 women were studied to investigate the effects of acute strenuous exercise on hemostasis after obtaining their informed consent. After familiarization, they performed exercise on a bicycle ergometer at 75% of their predetermined maximal workload until exhaustion. Bleeding time, measured by the Simplate method, and venous blood ...
Tajima Y - - 1989
We examined the anticoagulant effects of phosphotungstate (PTA). PTA inhibited factors IIa and Xa activity only in the presence of antithrombin III (ATIII). The inhibitory effect of PTA on IIa was much smaller than that on Xa. When PTA was added to heparin (Hep), the inhibitory effect of Hep on ...
Martin T W - - 1989
PURPOSE: The association between sickle cell trait (SCT) and complications related to exercise may be explained if exercise-induced sickling interferes with capillary blood flow and causes tissue ischemia and functional abnormalities. To test this hypothesis, we measured sickling and blood gas values in venous and arterial blood of an exercising ...
Spodaryk K - - 1989
The aim of this study was to determine the changes of the basic parameters of the erythrocyte system and the activity of some red blood cell (RBC) enzymes prior to and after a single physical effort leading to exhaustion. The study was carried out on male Wistar rats subjected to ...
Mottaghy K - - 1989
Application of heparin bonded surfaces (HBS) in the extracorporeal circuit (ECC) might avoid or at least reduce conventional heparin administration and would be of great benefit, especially in long-term perfusion. In this study, six sheep had a veno-venous bypass using membrane oxygenators with either total HBS or, in a control ...
Mukhopadhyay S - - 1989
Uptake of Cd by human RBC in vitro was studied. The uptake was found to be biphasic with a rapid initial phase followed by a slower second phase which was still increasing at the time of the last experiment (60 min). Both the phases were found to be independent of ...
Ohba Y - - 1989
An abnormal profile of cation exchange high performance liquid chromatography for the determination of Hb A1c led to the discovery of a new hemoglobin variant with a His----Tyr substitution at position 97(FG4) of the beta chain. The variant comprised about equal proportion to normal Hb A. It showed an increased ...
Araki R - - 1989
We developed a method for quantitating absolute value of Hb oxygenation and that of redox state of cyt. aa3 on the basis of multiple regression analysis of near-infrared spectrophotometric data. Flattening of the spectrum of Hb in both RBC suspension and the brain in situ was observed. This phenomenon was ...
Bartels P C - - 1988
A method is described for the assessment of the fraction of microcytes from the red blood cell (RBC) size distribution histogram. For quantification of the fraction of microcytes an upper threshold corresponding with a RBC volume of 70 fL is established. The reference interval for the fraction of microcytes covers ...
Goto S - - 1988
NaUCC-2, a choriocarcinoma cell line, was derived from a patient who had a very poor clinical response to combination chemotherapy. Methotrexate (MTX) might have inhibited the antitumor effect of dactinomycin. To investigate this point, in vitro studies were performed to determine the sensitivity and uptake of MTX and dactinomycin (administered ...
Fok A K - - 1988
Digestive vacuole (DV) formation in Paramecium can be separated into four steps: sequestration and recycling of the spent DV membrane, sweeping and concentrating of particles into the nascent DV, vacuole growth, and the release of the nascent DV. How the size, load and surface charge of solid particles affected formation ...
Vandewalle H - - 1988
Ten healthy subjects performed two exercise sessions similar to an endurance training session for average athletes (1 cycling exercise at 85% of the maximal heart rate on a Monark cycle ergometer). In the first session, the subjects were not allowed to drink during exercise. During the second session, the same ...
Shimizu T - - 1988
Levels of erythrocyte glycolytic intermediates after the phosphofructokinase (PFK) step, including 2,3-bisphosphoglycerate (2,3-DPG), were decreased at rest in patients from separate families with type VII glycogenosis. The concentration of 2,3-DPG was about half of the normal control value during a period of unrestricted daily activity but was further decreased to ...
Goretski J - - 1988
A spectrophotometric method has been developed that uses extracellular hemoglobin (Hb) to trap nitric oxide (NO) released during denitrification as nitrosyl hemoglobin (HbNO). The rate of complexation of NO with Hb is about at the diffusion controlled limit for protein molecules and the product, HbNO, is essentially stable. Hb was ...
Hespel P - - 1988
The intracellular concentrations and transmembrane fluxes of Na+ and K+ in erythrocytes, and plasma lipids were investigated in 30 middle-aged volunteers, before and after physical training. During the first 4 months of the study, half of the subjects (group A) were subjected to a training programme (3 h/week), while the ...
Schmidt W - - 1988
The effect of three weeks ergometer training (Tr) 5 times a week for 45 min at 70% VO2max by 6 subjects on erythrocyte turnover and haemoglobin O2 affinity has been studied. Increased reticulocytosis could be observed from the second day after beginning Tr until a few days after its end, ...
Aminoff D - - 1988
Red blood cells (rbcs) have a definite life-span in circulation, 120 days in humans (and 60 days in rat). This involves the turnover of the equivalent of 2 x 10(11) rbcs per day in a normal adult. Many time-dependent physical, chemical, as well as biochemical and immunologic changes are associated ...
Dobashi T - - 1988
We have measured the sedimentation curves of swine erythrocytes in a physiological saline solution in inclined glass tubes. The curves are well fitted to the exponential type equation l = a[1 - exp(-bt)] for the tilt angle theta in the range of theta less than 80 degrees and hematocrits from ...
Lachant N A - - 1987
Red blood cell (RBC) antioxidant defense was investigated in eight individuals with hemoglobin E (Six EE and two E-B(+) thalassemia) and compared to that in six individuals with thalassemia and ten normal subjects. Individuals with hemoglobin E had increased incubated Heinz body formation (68% +/- 18%; p less than 0.001) ...
Milligan C L - - 1987
In vitro, exogenous adrenaline reduced the Bohr and Root shifts caused by elevated PaCO2 and depressed plasma pH in rainbow trout blood, but not in starry flounder blood. In vivo immediately after exercise, plasma adrenaline (Ad) and noradrenaline (NAd) increased about 12-fold in rainbow trout. Associated with this catecholamine mobilization ...
Muza S R - - 1987
We measured the physical exercise capabilities of U.S. Army Special Forces soldiers (male) and determined the subsequent ergogenic influence of autologous blood reinfusion. Twelve subjects (Ss) completed maximal exercise treadmill testing in a comfortable (Ta = 20 degrees C, Tdp = 9 degrees C) environment. Six Ss were later transfused ...
Giger U - - 1987
Seven English Springer Spaniels (6 adult males and 1 female) with chronic hemolysis and sporadic intravascular hemolytic crises were determined to have a deficiency in erythrocyte phosphofructokinase (PFK) activity, a key regulatory enzyme of anaerobic glycolysis. Intermittent severe pigmenturia concomitant with weakness, lethargy, and anorexia were the major clinical signs ...
Jacobson D M - - 1987
We separated 24 patients with biopsy-proved giant cell arteritis into three groups based on erythrocyte sedimentation rates (ESRs) at clinical presentation: low, 1 to 40 mm/h; high, 41 to 80 mm/h; and very high, greater than 80 mm/h. The presence of anemia in the very high ESR group compared with ...
Rand J S - - 1987
An exercise-induced malignant hyperthermia-like syndrome developed in an English Springer Spaniel. Moderate exercise resulted in pronounced hyperlactacidemia, dyspnea, and hyperthermia. Before exercise, the dog had high activities of serum muscle enzymes, mild reticulocytosis, abnormally increased erythrocyte osmotic fragility, and a positive result from the caffeine-halothane contracture test. This report supports ...
Stäubli M - - 1987
125I albumin was used to assess the amount of trapped fluid after microhematocrit centrifugation of erythrocytes suspended in buffers of different osmolality. Surprisingly the total amount of trapped fluid per volume unit of packed erythrocytes decreased with decreasing osmolality of the suspending buffer despite erythrocyte swelling. However, if the contribution ...
Sawka M N - - 1987
Induced erythrocythemia is associated with a variable increase in maximal oxygen uptake. To examine the roles of the magnitude of change in hemoglobin concentration and the individual's initial aerobic fitness in this effect, we combined individual data from our own research and three other studies. In each study freeze-preserved erythrocytes ...
Gimenez M - - 1987
The influence of exercise on hormonal and total white blood cells (WBC), lymphocytes (L). Granulocytes (GR), and platelet (P) count responses was studied in: twenty-five patients with chronic airway obstruction (CAO, 47 +/- 1.8 years, mean +/- SEM) and thirteen normal subjects (N, 36 +/- 2.6 years). They performed a ...
Deuster P A - - 1987
This study was conducted to determine whether short-term, high-intensity anaerobic exercise alters Mg homeostasis. Thirteen men performed intermittent bouts of treadmill running at 90% of their predetermined maximum O2 uptake until exhaustion on one occasion during a week in which all men were consuming a standard diet (115 mg Mg/1,000 ...
Fantozzi R - - 1987
The early diagnosis and evaluation of the biological consequences of alcohol abuse are reviewed in a population of 401 chronic alcoholics admitted to our Toxicological Unit from January 1973 to the end of December 1984; selected cases were treated with disulfiram implantation. The results of the study indicate that anemia ...
Celsing F - - 1987
Increasing the haemoglobin concentration ([Hb]) improves the oxygen transport capacity but it also increases the viscosity of the blood. The influence of changes in [Hb] and viscosity on submaximal exercise capacity and maximal aerobic power was investigated in eight healthy males in varying states of training and with a normal ...
Jensen F B - - 1987
Exercise-stress in tench resulted in severe acidosis in both the red cells and the extracellular fluid in vivo. These coincident pH decreases conformed to the in vitro pHi-pHe relationship for tench blood in the oxygenated state. The extracellular acidosis was primarily respiratory in winter and metabolic in spring and summer. ...
Wegner G - - 1987
The deformability changes of erythrocytes during 35 days of storage in different resuspension media were characterized by a filtration procedure. The filterability of erythrocytes stored in CDS-AG medium decreased drastically, whereas the filterability of erythrocytes stored in SAGM and SAGS medium decreased only slightly. The MCHC change of stored erythrocytes ...
Pawlak A L - - 1987
Effect of physical effort on haemoglobin-oxygen affinity was studied in whole blood of 28 healthy males. In persons showing decrease in pH gradient between plasma and erythrocytes after physical effort, a parallel decrease in apparent, normalized for intraerythrocytic pH (pHe), Hb-oxygen affinity was noted. An increase in pH gradient after ...
Slomiany B L - - 1986
The effect of lysolecithin and lecithin on gastric mucin viscosity, permeability to hydrogen ion, and degradation by pepsin was investigated. Preincubation with lysolecithin produced a marked decrease in the glycoprotein viscosity. This decrease was concentration-dependent and at 10 mM lysolecithin reached a value of 74%. A 25% increase in mucin ...
Kiel J L - - 1986
Red blood cells were collected from Landrace X Duroc pigs in pooled and single batches. The RBC were stored for 24 hours to 20 days and exposed to 1 or more chemical and physical stressors. The chemicals were pyruvate, lactate, inosine, concanavalin A-luminol-bovine serum albumin conjugate, hydrogen peroxide, L-mimosine, and ...
Nguyen Phu D - - 1986
The specific conductance (G) for O2 transfer by red blood cells (RBCs) of chicken and muscovy duck was measured using the experimental (stopped-flow) and analytical techniques (RBC model) previously applied to human RBC (Yamaguchi, Nguyen Phu, Scheid & Piiper, 1985). Avian RBCs behaved similarly to human RBCs: G values were ...
Hespel P - - 1986
The effect of exercise on the intraerythrocyte cationic concentrations and transmembrane fluxes such as the Na+-K+-adenosinetriphosphatase (ATPase) pump, the Na+-K+ cotransport, and the Na+-Li+ countertransport system was studied in 11 normal male volunteers. All subjects performed an uninterrupted incremental exercise test on a bicycle ergometer, starting at an initial work ...
Gordis E - - 1986
We applied the technique of isoelectric focusing (IEF) on immobilized pH gradients (LKB) to determine whether acetaldehyde-modified hemoglobins (Hb) prepared in vitro with unphysiological acetaldehyde concentrations have clinical relevance. This technique separates proteins with pl less than 0.01 and provides detail about hemoglobins not otherwise separable. We performed two kinds ...
Primmett D R - - 1986
Rainbow trout were subjected to burst swimming to exhaustion followed by 4 h aerobic swimming at 80% critical swimming velocity. Severe physiological disturbances, including a marked plasma acidosis caused by the burst swim, were corrected during the 4 h of subsequent aerobic exercise. Erythrocytic pH and arterial oxygen content increased, ...
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