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Durand Matthew J MJ Department of Medicine, Cardiology Division, and Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, - - 2014
Exercise is a powerful therapy for preventing the onset of and slowing the progression of cardiovascular disease. Increased shear stress during exercise improves vascular homeostasis by both decreasing reactive oxygen species and increasing nitric oxide bioavailability in the endothelium. While these observations are well accepted as they apply to individuals ...
Moraes Cristiane C Graduate Program in Cardiovascular Sciences, Fluminense Federal University (UFF), Niterói, RJ, Brazil, - - 2014
Patients undergoing hemodialysis (HD) present persistent inflammation and protein-energy wasting (PEW), which contributes to high rates of mortality. This study aimed to assess the effects of a resistance exercise training program (RETP) on inflammation and PEW in HD patients. Thirty-seven patients (56.7 % men, 45.9 ± 14.1 years, 23.5 ± 3.9 kg/m(2)) performed 6 months of intradialytic RETP. ...
Nussbaumer M M Department of Sport, Exercise and Health, Division of Sports and Exercise Medicine, Medical Faculty, University of Basel, Birsstrasse 320B, 4052, Basel, - - 2014
Alterations of retinal vessel diameters are associated with increased cardiovascular risk. We aimed to investigate changes in retinal vessel diameters in response to acute dynamic exercise of different intensities and whether these changes are age dependent. Seventeen healthy seniors (median (IQR) age 68 (65, 69) years) and 15 healthy young ...
Delussu Anna Sofia - - 2014
Robotic-assisted walking after stroke provides intensive task-oriented training. But, despite the growing diffusion of robotic devices little information is available about cardiorespiratory and metabolic responses during electromechanically-assisted repetitive walking exercise. Aim of the study was to determine whether use of an end-effector gait training (GT) machine with body weight support ...
Ong Peter P Department of Cardiology, Robert Bosch Hospital, Stuttgart, - - 2014
The exercise electrocardiogram (ECG) is a standard examination in patients with suspected coronary artery disease. However, despite a pathologic result, many patients undergoing diagnostic coronary angiography do not have any significant epicardial stenosis. In this study, we assessed the relation between a pathologic exercise ECG and coronary microvascular dysfunction in ...
Kirkman Danielle L DL School of Sport, Health and Exercise Sciences, Bangor University, Bangor, Wales, UK, - - 2014
The anabolic response to progressive resistance exercise training (PRET) in haemodialysis patients is unclear. This pilot efficacy study aimed to determine whether high-intensity intradialytic PRET could reverse atrophy and consequently improve strength and physical function in haemodialysis patients. A second aim was to compare any anabolic response to that of ...
Weissmann Norbert N 1University of Giessen and Marburg Lung Center - - 2014
Pulmonary hypertension (PH) is a disease with a poor prognosis characterized by a vascular remodeling process and an increase in pulmonary vascular resistance. While a variety of reports demonstrated that exercise training exerts beneficial effects on exercise performance and quality of life in PH patients it is not known how ...
Geary Kate K *Anschutz Medical Campus, University of Colorado, 13001 E 17th Place, Aurora, CO 80045, - - 2014
Our translational research group focuses on addressing the problem of exercise defects in diabetes with basic research efforts in cell and rodent models and clinical research efforts in subjects with diabetes mellitus. CREB (cAMP-response-element-binding protein) regulates cellular differentiation of neurons, β-cells, adipocytes and smooth muscle cells; it is also a ...
Zagatina A A Cardiocenter "Medika" St. Petersburg, Russian Federation - - - 2014
Ischemic segments cannot develop a sufficient amount of strength during systole, so theoretically they begin to contract later in comparison with non-ischemic zones. There is a lack of information about methods that can detect dyssynchrony during exercise in patients with QRS not longer 100 ms. The aim of the study ...
Duttaroy Smita S Department of Molecular and Clinical Medicine/Cardiology, University of Gothenburg, - - 2014
In coronary artery disease (CAD), circulating angiogenic factors have been seen to increase, possibly as a response to ischaemia. Regular physical activity (PA) is recommended for prevention and treatment of CAD, but more research is needed to optimise PA regimes. We investigated the effect of home-based high frequency exercise (HFE) ...
Zhu Li-Xia LX School of Nursing, The Hong Kong Polytechnic University, Hong Kong; Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address: - - 2014
To determine whether a transtheoretical model-based exercise stage-matched intervention (ESMI) has positive effects on the exercise behavior of sedentary patients with coronary heart disease (CHD). The study was a randomized controlled trial with a repeated measures design. Participants (N=196) were randomly allocated to either a conventional (C) group, a patient ...
Borland Maria M NärRehab Physiotherapy Unit, Primary Healt Care, , Alings8s, Sweden. - - 2014
Objective: To investigate how group-based exercise affects the levels of physical activity, physical fitness and health- related quality of life (HRQoL) in patients with chronic heart failure and comorbidities. Design: Randomized controlled trial. Patients: A total of 48 patients (10 women, 38 men), mean age 71 years (standard deviation 8 ...
Hirashiki Akihiro A Department of Advanced Medicine in Cardiopulmonary Disease, Nagoya University Graduate School of Medicine, Nagoya 466-8560, - - 2014
The 6-minute walking distance is often used for assessing the exercise capacity under the treatment with an endothelin receptor antagonist (ERA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH). The cardiopulmonary exercise testing (CPX) was reported to be more useful for the patients with pulmonary arterial hypertension (PAH), however, few ...
Dost Gulseren G Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Adiyaman University, Adiyaman, - - 2014
Exercises aiming to strengthen the upper extremities are recommended to increase activities of daily living (ADLs) in patients with spinal cord injury (SCI). The aim of this study was to compare the effects of upper extremity progressive resistance exercises (PRE) and endurance exercises (EE) performed with an arm ergometer in ...
Gunasekera Roshan C RC Centre for Sport and Exercise Science, Sheffield Hallam University, Sheffield, United - - 2014
We sought to describe patient recruitment and experiences in a randomised controlled trial of a 12-week (thrice weekly) supervised exercise program for patients with small abdominal aortic aneurysm (AAA). Potential patients were identified via AAA surveillance lists and vascular clinics and invited to participate in the study. Upon completion of ...
Mahadevan Karunasai K 2Department of Pathology, University of Virginia School of Medicine and Medical Laboratories, University of Virginia Health System, Charlottesville, VA; 3Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA; 1School of Engineering and Applied Science, University of Virginia, Charlottesville, - - 2014
A patient with recurrent pulmonary emboli collected heart rate data during exercise, which provided important premorbid clues to changes in cardiopulmonary exercise tolerance coincident with accrual of thrombus in the central circulation. On both occasions, chronotropic incompetence (CI) preceded the pulmonary emboli events. When patients with programmed exercise goals notice ...
Tahan Fulya - - 2014
Background • Some studies have shown the beneficial effects of yoga for individuals with bronchial hyperreactivity with regard to (1) a reduction in the use of rescue medication, (2) an increase in exercise capacity, and (3) an improvement in lung function. Despite the fact that yoga is promising as a ...
Kim Ki-Jong KJ Department of Physical Therapy, Graduate School of Dongshin University, Republic of - - 2014
[Purpose] The purpose of this study was to implement combined muscle strengthening and proprioceptive exercises to examine the effects of combined exercises on functional ankle instability. [Subjects and Methods] Experiments were conducted with 30 adult males and females. The study subjects were randomly assigned to either a control group (Group ...
Bhatt Digant V DV From the Department of Cardiology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, and the University of Illinois College of Medicine at - - 2014
Gas exchange measurements obtained during submaximal exercise have been shown to provide prognostic and diagnostic information in patients with heart failure (HF) and to differentiate heart versus lung limitations in patients with unexplained dyspnea. The aim of our study was to assess the clinical utility of submaximal cardiopulmonary exercise testing ...
Franklin Nina C NC Department of Physical Therapy, University of Illinois at Chicago, Chicago, IL; Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago, Chicago, - - 2014
To determine if lower extremity exercise-induced muscle injury (EMI) reduces vascular endothelial function of the upper extremity and if massage therapy (MT) improves peripheral vascular function after EMI. Randomized, blinded trial with evaluations at 90 minutes, 24 hours, 48 hours, and 72 hours. Clinical research center at an academic medical ...
Bikov Andras A Department of Pulmonology, Semmelweis University, Budapest, - - 2014
Exercise-induced bronchoconstriction (EIB) is the temporary narrowing of the airways caused by physical exercise. Its exact pathophysiology is unclear; however, acute changes in airways pH may play a role. Exhaled breath condensate (EBC) pH was suggested as a surrogate indicator for airway acid-base status, but its value is also affected ...
Baltgalvis Kristen A KA Rigel Pharmaceuticals, - - 2014
Intermittent claudication is a form of exercise intolerance characterized by muscle pain during walking in patients with peripheral artery disease (PAD). Endothelial cell and muscle dysfunction are thought to be important contributors to the etiology of this disease, but a lack of preclinical models that incorporate these elements and measure ...
Ihsan Mohammed M 1Centre for Sports and Exercise Science Research, School of Exercise and Health Sciences, Edith Cowan University, Perth, Australia; 2School of Human Life Sciences, University Of Tasmania, Launceston, Australia; 3School of Medicine, Deakin University, Melbourne, Australia; 4Liggins Institute, University of Auckland, Auckland, New - - 2014
To investigate the influence of localized muscle cooling on post-exercise vascular, metabolic and mitochondrial-related gene expression. Nine physically active males performed 30 min of continuous running at 70% of their maximal aerobic velocity (Vmax), followed by intermittent running to exhaustion at 100% Vmax. Following exercise, subjects immersed one leg in ...
Duggan Catherine C Public Health Sciences, Fred Hutchinson Cancer Research - - 2014
Background: Increased physical activity is associated with decreased risk of several types of cancer, but underlying mechanisms are poorly understood. Angiogenesis, where new blood vessels are formed, is common to adipose tissue formation/remodelling and tumor vascularization. Methods: We examined effects of a 12-month 45 minutes/day, 5 days/week moderate-intensity aerobic exercise ...
Park Jae Hyo JH Department of Physical Therapy, College of Rehabilitation Science, Daegu University, Republic of - - 2014
[Purpose] The purpose of this study was to examine the effects of trunk stabilization exercise using a saing on the balance ability of patients with hemiplegia. [Subjects] Forty patients with hemiplegia resulting from stroke were divided into a sling exercise group (SEG, n=20) and a mat exercise group (MEG, n=20). ...
Heaps Cristine L CL Institute for Comparative Cardiovascular Science and Biomedical Devices; Department of Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences,Texas A&M University, College Station, TX, - - 2014
Test the hypothesis that exercise training enhances sustained relaxation to persistent endothelium-dependent vasodilator exposure via increased nitric oxide contribution in small coronary arteries of control and ischemic hearts. Yucatan swine were designated to a control group or a group in which an ameroid constrictor was placed around the proximal LCX. ...
Johnson-Warrington Vicki V NIHR CLAHRC-LNR, Pulmonary Rehabilitation Research Group, Glenfield Hospital, University Hospitals Leicester NHS Trust, Leicester, the United Kingdom (Mss Johnson-Warrington and Harrison and Drs Mitchell, Steiner, Morgan, and Singh); and Faculty of Health and Life Sciences, Coventry University, Coventry, the United Kingdom (Dr - - 2014
Patients with chronic obstructive pulmonary disease (COPD) are often classified by Medical Research Council (MRC) dyspnea grade and comparisons thus made to healthy individuals. The MRC grade of a healthy population is assumed to be grade 1, although this may be inaccurate. Physical activity and exercise capacity are not well-defined ...
Moura Carolina Soares CS Department of Food and Nutrition, Faculty of Food Engineering, University of Campinas (UNICAMP), Campinas, São Paulo, - - 2014
Whey protein hydrolysate (WPH) intake has shown to increase HSP70 expression. The aim of the present study was to investigate whether WPH intake would also influences HSP90, HSP60 and HSP25 expression, as well as associated parameters. Forty-eight male Wistar rats were divided into sedentary (unstressed) and exercised (stressed) groups, and ...
Sakamoto Keiko K Research Center of Sports Medicine and Balneology, Wakayama Medical University, Wakayama, - - 2014
Background: Spasticity is a major disabling symptom in stroke patients. Clinically, one of the goals of management of stroke patients should be to reduce spasticity. Recent evidence suggests that motor recovery after stroke comprises a hierarchical, dynamic framework of interacting mechanisms in brain cortex. We hypothesized that unaffected arm exercise ...
Ghio Stefano S Fondazione IRCCS Policlinico San Matteo, - - 2014
Patients with chronic thromboembolic pulmonary hypertension (CTEPH), despite successful pulmonary endarterectomy (PEA), can continue to suffer from a limitation in exercise capacity. The objective of this study was to assess whether pulmonary arterial compliance is a predictor of exercise capacity after PEA.Right heart haemodynamics, treadmill incremental exercise test, spirometry, carbon ...
Bender Shawn B SB University of Missouri-Columbia, United - - 2014
Vascular dysfunction has been associated with familial hypercholesterolaemia (FH), a severe form of hyperlipidaemia. We recently demonstrated that swine with FH exhibit reduced exercise-induced systemic, but not pulmonary, vasodilatation involving reduced nitric oxide (NO) bioavailability. Since NO normally limits endothelin (ET) action, we examined the hypothesis that reduced systemic vasodilatation ...
Zhou Zhichao Z 1Erasmus University Medical Center - - 2014
Both phosphodiesterase 5 (PDE5) inhibition and endothelin (ET) receptor blockade have been shown to induce pulmonary vasodilation. However, little is known about the effect of combined blockade of these two vasoconstrictor pathways. Since nitric oxide (NO) exerts its pulmonary vasodilator influence via production of cyclic guanosine monophosphate (cGMP) as well ...
Isaksen Kjetil K Stavanger University Hospital, Stavanger, - - 2014
Aerobic interval training (AIT) has been shown to be superior to moderate continuous exercise training in improving exercise capacity and endothelial function in patients with both coronary artery disease and heart failure (HF). The objective of this study was to evaluate this training modality in patients with HF and an ...
Pramodhyakul N N 1] School of Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand [2] Improvement of Physical Performance and Quality of Life (IPQ) research group, Khon Kaen University, Khon Kaen, - - 2014
Study design:An experimental, cross-sectional study.Objectives:To investigate effects of using a visuotemporal cue on the walking ability of independent ambulatory subjects with spinal cord injury (SCI) as compared with healthy subjects.Setting:A tertiary rehabilitation center, Thailand.Methods:Forty independent ambulatory subjects with SCI and healthy subjects participated in the study (20 subjects per group). ...
Chung Eunjung E Department of Physical Therapy, Andong Science College, Andong, Republic of - - 2014
Objective: The purpose of this study was to examine the feasibility of core stabilization exercise with real-time feedback on balance and gait function in patients with chronic hemiparetic stroke. Methods: Nineteen stroke subjects were enrolled in this study. The patients were randomly divided into the experimental (n = 10) and ...
Sponder Michael - - 2014
Type 2 diabetes mellitus (T2DM) is often associated with atherosclerotic changes in coronary vessels, most notably plaques. The angiostatic parameter endostatin is able to inhibit angiogenesis in tissue as well as in plaques and therefore plays an important role in physiological and pathological neovascularisation. The aim of the present study ...
Park Han-Ki HK Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul, - - 2014
Exercise-induced bronchoconstriction (EIB) was recently classified into EIB alone and EIB with asthma, based on the presence of concurrent asthma. Differences between EIB alone and EIB with asthma have not been fully described. We retrospectively reviewed who visited an allergy clinic for respiratory symptoms after exercise and underwent exercise bronchial ...
Ross Mark D MD 1Department of Health, Sport and Exercise Science, Waterford Institute of Technology, Waterford, IRELAND; and 2School of Life, Sport and Social Sciences, Edinburgh Napier University, Edinburgh, Scotland, UNITED - - 2014
Bone marrow-derived endothelial progenitor cells (EPC) are involved in vascular growth and repair. They increase in the circulation after a single bout of aerobic exercise, potentially related to muscle ischemia. Muscular endurance resistance exercise (MERE) bouts also have the potential to induce muscle ischemia if appropriately structured. The objective of ...
Miyamoto Naomi N Department of Cardiopulmonary Rehabilitation Science, Nagasaki University Graduate School of Biomedical - - 2014
Air pollution in Japan caused respiratory disease, such as chronic bronchitis and asthma, in many individuals in the 1960s. Although air pollution has decreased, many victims of air pollution-related respiratory disease are limited in their activities of daily living because of respiratory symptoms. The purpose of this study was to ...
Guenette Jordan - - 2014
The classification of mild chronic obstructive pulmonary disease (COPD) requires a postbronchodilator forced expiratory volume in 1 s (FEV1) to forced vital capacity ratio <0.7 and an FEV1 ≥80% predicted. Given their relatively well-preserved spirometry, some have argued that respiratory symptoms in patients with mild COPD are unlikely to be ...
Jung Kyoungsim K Department of Physical Therapy, The Graduate School, Sahmyook - - 2014
Trunk instability is one of main problems in survivors following stroke. We investigated the effects of weight-shift training (WST) on an unstable surface in sitting position on trunk control, proprioception, and balance in individuals with chronic hemiparetic stroke. Eighteen participants with chronic hemiparetic stroke were recruited and were allocated to ...
Fujie Shumpei S Faculty of Sport and Health Science, Ritsumeikan University, Shiga, - - 2014
Aging-induced deterioration of arterial stiffness is decreased by regular exercise, and increased nitric oxide (NO) production participates in this effect. Apelin regulates endothelial NO synthase in endothelial cells, promoting NO production. However, the effect of aerobic exercise training on circulating apelin levels in healthy middle-aged and older adults remains unknown. ...
Currie Katharine D KD Department of Kinesiology, McMaster University, 1280 Main Street West, Hamilton, ON, Canada L8S - - 2014
This study examined the acute endothelial responses to an exercise bout in coronary artery disease (CAD) patients. Nineteen males with CAD (63 ± 8 years) were assessed at rest and 15 minutes following a submaximal exercise bout (recovery). Brachial artery endothelial-dependent function was assessed using flow-mediated dilation (FMD). Brachial artery ...
Wahl Patrick P Institute of Training Science and Sport Informatics, German Sport University, Cologne, Cologne, Germany; Department of Molecular and Cellular Sport Medicine, Institute of Cardiovascular Research and Sport Medicine, German Sport University Cologne, Cologne, Germany; The German Research Centre of Elite Sport, German Sport University Cologne, Cologne, - - 2014
Endothelial microparticles (EMP) are complex vesicular structures shed from activated or apoptotic endothelial cells. As endurance exercise affects the endothelium, the objective of the study was to examine levels of EMP and angiogenic growth factors following different endurance exercise protocols. 12 subjects performed 3 different endurance exercise protocols: 1. High ...
Kettunen Oili O Department of Health and Exercise & Paavo Nurmi Center, University of Turku, 20520 Turku, Finland. - - 2014
Objectives: This study's objective was to assess the effects of a 12-month physical exercise intervention on work ability (WAI) and cardiorespiratory fitness (CRF) in healthy working adults. Methods: The study group had 371 participants, of which 338 (212 women and 126 men) were allocated in the exercise group and 33 ...
Moisseiev Elad E Department of Ophthalmology, Tel Aviv Medical Center, Tel Aviv, - - 2014
We report a 19-year-old patient who developed a central retinal vein occlusion (CRVO) with significant macular edema and visual impairment following intense exercise and dehydration. The patient was treated with 3 intravitreal bevacizumab injections with complete resolution. A review of the literature on the cause and treatment for CRVO in ...
Cameron-Tucker Helen L HL Centre of Research Excellence for Chronic Respiratory Disease and Lung Aging, School of Medicine, University of Tasmania, Hobart, TAS, - - 2014
Both exercise and self-management are advocated in pulmonary rehabilitation for people with chronic obstructive pulmonary disease (COPD). The widely used 6-week, group-based Chronic Disease Self-Management Program (CDSMP) increases self-reported exercise, despite supervised exercise not being a program component. This has been little explored in COPD. Whether adding supervised exercise to ...
Andrzejewski Waldemar W Department of Physiotherapy, University School of Physical Education, 35/p-4 Paderewskiego Street, 51-612 Wroclaw, Poland ; Public Higher Medical Professional School, 68 Katowicka Street, 45-060 Opole, - - 2014
Physical exercise and massage are regarded as key factors in regulating tendon structure. However, information on the mechanism through which massage influences the structure and biology of a tendon is scarce. In this study, we attempted to define the impact of these two activities on rat tendons by using morphological ...
Deepak T H - - 2014
Pulmonary rehabilitation (PR) is an evidence-based intervention in patients with chronic obstructive pulmonary disease (COPD) which improves the exercise capacity and quality of life (QoL). We studied 60 patients after an episode of acute exacerbation of COPD (AECOPD). They were randomised to receive conventional treatment without pulmonary rehabilitation (CTWPR) (n=30) ...
O'Donnell Denis E DE Division of Respiratory and Critical Care Medicine, Respiratory Investigation Unit, Queen's University and Kingston General Hospital, Kingston, ON, - - 2014
Dyspnea, exercise intolerance, and activity restriction are already apparent in mild chronic obstructive pulmonary disease (COPD). However, patients may not seek medical help until their symptoms become troublesome and persistent and significant respiratory impairment is already present; as a consequence, further sustained physical inactivity may contribute to disease progression. Ventilatory ...
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